DJ-1 (PARK7), a novel gene for autosomal recessive, early onset parkinsonism

Neurological Sciences

Volumn 24, Issue 3, 2003, Pages 159-160

  Bonifati, V ^a,b   Rizzu, P ^a   Squitieri, F ^c   Krieger, E ^d   Vanacore, N ^e   van Swieten, J C ^a   Brice, A ^f   van Duijn, C M ^a   Oostra, B ^a   Meco, G ^b   Heutink, P ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c IRCCS NEUROMED   (Italy)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^e ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE;

ANTIOXIDANT ACTIVITY; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CHROMOSOME 1P; COMPARATIVE GENE MAPPING; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; GENETIC LINKAGE; HUMAN; ITALY; LINKAGE ANALYSIS; MOLECULAR CLONING; NETHERLANDS; NONHUMAN; ONSET AGE; PARKINSON DISEASE; PARKINSONISM; PATHOGENESIS; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN FUNCTION;

CHROMOSOMES, HUMAN, PAIR 1; DNA MUTATIONAL ANALYSIS; FAMILY HEALTH; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUTATION; ONCOGENE PROTEINS; PARKINSONIAN DISORDERS;

EID: 0142217556     PISSN: 15901874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10072-003-0108-0     Document Type: Article

References (8)

1. van Duijn CM, Dekker MC, Bonifati V et al (2001) Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36. Am J Hum Genet 69:629-634
2. Bonifati V, Breedveld GJ, Squitieri F et al (2002) Localization of autosomal recessive early-onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset. Ann Neurol 51:253-256
3. Dekker M, Bonifati V, van Swieten J et al (2003) Clinical features and neuroimaging of PARK7-linked parkinsonism. Mov Disord (in press)
4. Bonifati V, Rizzu P, van Baren MJ et al (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299:256-259
5. Mitsumoto A, Nakagawa Y, Takeuchi A et al (2001) Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat. Free Radic Res 35:301-310
6. de Nobel H, Lawrie L, Brul S et al (2001) Parallel and comparative analysis of the proteome and transcriptome of sorbic acid-stressed Saccharomyces cerevisiae. Yeast 18:1413-1428
7. Trotter EW, Kao, CM, Berenfeld L et al (2002) Misfolded proteins are competent to mediate a subset of the responses to heat shock in Saccharomyces cerevisiae. J Biol Chem 277:44817-44825
8. Dawson TM, Dawson VL (2003) Rare genetic mutations shed light on the pathogenesis of Parkinson disease. J Clin Invest 111:145-151