-
1
-
-
0042035602
-
Human neurodegenerative disease modeling using Drosophila
-
Bonini N.M., Fortini M.E. Human neurodegenerative disease modeling using Drosophila. Annu. Rev. Neurosci. 26:2003;627-656.
-
(2003)
Annu. Rev. Neurosci.
, vol.26
, pp. 627-656
-
-
Bonini, N.M.1
Fortini, M.E.2
-
2
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand A.H., Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development. 118:1993;401-415.
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
3
-
-
0034703863
-
Mechanisms of chaperone suppression of polyglutamine disease: Selectivity, synergy and modulation of protein solubility in Drosophila
-
Chan H.Y., Warrick J.M., Gray-Board G.L., Paulson H.L., Bonini N.M. Mechanisms of chaperone suppression of polyglutamine disease. selectivity, synergy and modulation of protein solubility in Drosophila Hum. Mol. Genet. 9:2000;2811-2820.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 2811-2820
-
-
Chan, H.Y.1
Warrick, J.M.2
Gray-Board, G.L.3
Paulson, H.L.4
Bonini, N.M.5
-
4
-
-
0036850456
-
Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila
-
Chan H.Y., Warrick J.M., Andriola I., Merry D., Bonini N.M. Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila. Hum. Mol. Genet. 11:2002;2895-2904.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2895-2904
-
-
Chan, H.Y.1
Warrick, J.M.2
Andriola, I.3
Merry, D.4
Bonini, N.M.5
-
5
-
-
0035394668
-
Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice
-
Cummings C.J., Sun Y., Opal P., Antalffy B., Mestril R., Orr H.T., Dillmann W.H., Zoghbi H.Y. Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice. Hum. Mol. Genet. 10:2001;1511-1518.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1511-1518
-
-
Cummings, C.J.1
Sun, Y.2
Opal, P.3
Antalffy, B.4
Mestril, R.5
Orr, H.T.6
Dillmann, W.H.7
Zoghbi, H.Y.8
-
6
-
-
0032837196
-
Tissue-specific expression of dominant negative mutant Drosophila HSC70 causes developmental defects and lethality
-
Elefant F., Palter K.B. Tissue-specific expression of dominant negative mutant Drosophila HSC70 causes developmental defects and lethality. Mol. Biol. Cell. 10:1999;2101-2117.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 2101-2117
-
-
Elefant, F.1
Palter, K.B.2
-
7
-
-
0027515798
-
Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein
-
Ellis M.C., O'Neill E.M., Rubin G.M. Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein. Development. 119:1993;855-865.
-
(1993)
Development
, vol.119
, pp. 855-865
-
-
Ellis, M.C.1
O'Neill, E.M.2
Rubin, G.M.3
-
8
-
-
0028989063
-
Translational suppression by trinucleotide repeat expansion at FMR1
-
Feng Y., Zhang F., Lokey L.K., Chastain J.L., Lakkis L., Eberhart D., Warren S.T. Translational suppression by trinucleotide repeat expansion at FMR1. Science. 268:1995;731-734.
-
(1995)
Science
, vol.268
, pp. 731-734
-
-
Feng, Y.1
Zhang, F.2
Lokey, L.K.3
Chastain, J.L.4
Lakkis, L.5
Eberhart, D.6
Warren, S.T.7
-
9
-
-
0034597833
-
Identification of genes that modify ataxin-1-induced neurodegeneration
-
Fernandez-Funez P., Nino-Rosales M.L., de Gouyon B., She W.C., Luchak J.M., Martinez P., Turiegano E., Benito J., Capovilla M., Skinner P.J.et al. Identification of genes that modify ataxin-1-induced neurodegeneration. Nature. 408:2000;101-106.
-
(2000)
Nature
, vol.408
, pp. 101-106
-
-
Fernandez-Funez, P.1
Nino-Rosales, M.L.2
De Gouyon, B.3
She, W.C.4
Luchak, J.M.5
Martinez, P.6
Turiegano, E.7
Benito, J.8
Capovilla, M.9
Skinner, P.J.10
-
10
-
-
0030584086
-
Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye
-
Freeman M. Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. Cell. 87:1996;651-660.
-
(1996)
Cell
, vol.87
, pp. 651-660
-
-
Freeman, M.1
-
11
-
-
0030746053
-
Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance
-
Gabai V.L., Meriin A.B., Mosser D.D., Caron A.W., Rits S., Shifrin V.I., Sherman M.Y. Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance. J. Biol. Chem. 272:1997;18033-18037.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18033-18037
-
-
Gabai, V.L.1
Meriin, A.B.2
Mosser, D.D.3
Caron, A.W.4
Rits, S.5
Shifrin, V.I.6
Sherman, M.Y.7
-
12
-
-
0036345801
-
Neuronal intranuclear inclusions in a new cerebellar tremor/ataxia syndrome among fragile X carriers
-
Greco C.M., Hagerman R.J., Tassone F., Chudley A.E., Del Bigio M.R., Jacquemont S., Leehey M., Hagerman P.J. Neuronal intranuclear inclusions in a new cerebellar tremor/ataxia syndrome among fragile X carriers. Brain. 125:2002;1760-1771.
-
(2002)
Brain
, vol.125
, pp. 1760-1771
-
-
Greco, C.M.1
Hagerman, R.J.2
Tassone, F.3
Chudley, A.E.4
Del Bigio, M.R.5
Jacquemont, S.6
Leehey, M.7
Hagerman, P.J.8
-
13
-
-
0036591683
-
The fragile X premutation: Into the phenotypic fold
-
Hagerman R.J., Hagerman P.J. The fragile X premutation. into the phenotypic fold Curr. Opin. Genet. Dev. 12:2002;278-283.
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 278-283
-
-
Hagerman, R.J.1
Hagerman, P.J.2
-
14
-
-
0035838379
-
Intention tremor, parkinsonism, and generalized brain atrophy in male carriers of fragile X
-
Hagerman R.J., Leehey M., Heinrichs W., Tassone F., Wilson R., Hills J., Grigsby J., Gage B., Hagerman P.J. Intention tremor, parkinsonism, and generalized brain atrophy in male carriers of fragile X. Neurology. 57:2001;127-130.
-
(2001)
Neurology
, vol.57
, pp. 127-130
-
-
Hagerman, R.J.1
Leehey, M.2
Heinrichs, W.3
Tassone, F.4
Wilson, R.5
Hills, J.6
Grigsby, J.7
Gage, B.8
Hagerman, P.J.9
-
15
-
-
0037092598
-
Retinal development in Drosophila: Specifying the first neuron
-
Hsiung F., Moses K. Retinal development in Drosophila. specifying the first neuron Hum. Mol. Genet. 11:2002;1207-1214.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1207-1214
-
-
Hsiung, F.1
Moses, K.2
-
16
-
-
0031030360
-
The Drosophila mushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells
-
Ito K., Awano W., Suzuki K., Hiromi Y., Yamamoto D. The Drosophila mushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells. Development. 124:1997;761-771.
-
(1997)
Development
, vol.124
, pp. 761-771
-
-
Ito, K.1
Awano, W.2
Suzuki, K.3
Hiromi, Y.4
Yamamoto, D.5
-
17
-
-
0037384643
-
Fragile X premutation tremor/ataxia syndrome: Molecular, clinical, and neuroimaging correlates
-
Jacquemont S., Hagerman R.J., Leehey M., Grigsby J., Zhang L., Brunberg J.A., Greco C., Des Portes V., Jardini T., Levine R.et al. Fragile X premutation tremor/ataxia syndrome. molecular, clinical, and neuroimaging correlates Am. J. Hum. Genet. 72:2003;869-878.
-
(2003)
Am. J. Hum. Genet.
, vol.72
, pp. 869-878
-
-
Jacquemont, S.1
Hagerman, R.J.2
Leehey, M.3
Grigsby, J.4
Zhang, L.5
Brunberg, J.A.6
Greco, C.7
Des Portes, V.8
Jardini, T.9
Levine, R.10
-
18
-
-
0034629073
-
Genetic suppression of polyglutamine toxicity in Drosophila
-
Kazemi-Esfarjani P., Benzer S. Genetic suppression of polyglutamine toxicity in Drosophila. Science. 287:2000;1837-1840.
-
(2000)
Science
, vol.287
, pp. 1837-1840
-
-
Kazemi-Esfarjani, P.1
Benzer, S.2
-
19
-
-
0035394437
-
Reduced FMRP and increased FMR1 transcription is proportionally associated with CGG repeat number in intermediate-length and premutation carriers
-
Kenneson A., Zhang F., Hagedorn C.H., Warren S.T. Reduced FMRP and increased FMR1 transcription is proportionally associated with CGG repeat number in intermediate-length and premutation carriers. Hum. Mol. Genet. 10:2001;1449-1454.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1449-1454
-
-
Kenneson, A.1
Zhang, F.2
Hagedorn, C.H.3
Warren, S.T.4
-
20
-
-
0028360849
-
Cryptic and polar variation of the fragile X repeat could result in predisposing normal alleles
-
Kunst C.B., Warren S.T. Cryptic and polar variation of the fragile X repeat could result in predisposing normal alleles. Cell. 77:1994;853-861.
-
(1994)
Cell
, vol.77
, pp. 853-861
-
-
Kunst, C.B.1
Warren, S.T.2
-
21
-
-
0034426013
-
Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity
-
Li H., Li S.H., Johnston H., Shelbourne P.F., Li X.J. Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity. Nat. Genet. 25:2000;385-389.
-
(2000)
Nat. Genet.
, vol.25
, pp. 385-389
-
-
Li, H.1
Li, S.H.2
Johnston, H.3
Shelbourne, P.F.4
Li, X.J.5
-
22
-
-
0028147879
-
Ectopic and increased expression of Fasciclin II alters motoneuron growth cone guidance
-
Lin D.M., Goodman C.S. Ectopic and increased expression of Fasciclin II alters motoneuron growth cone guidance. Neuron. 13:1994;507-523.
-
(1994)
Neuron
, vol.13
, pp. 507-523
-
-
Lin, D.M.1
Goodman, C.S.2
-
23
-
-
0033830374
-
The chaperone function of hsp70 is required for protection against stress-induced apoptosis
-
Mosser D.D., Caron A.W., Bourget L., Meriin A.B., Sherman M.Y., Morimoto R.I., Massie B. The chaperone function of hsp70 is required for protection against stress-induced apoptosis. Mol. Cell. Biol. 20:2000;7146-7159.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7146-7159
-
-
Mosser, D.D.1
Caron, A.W.2
Bourget, L.3
Meriin, A.B.4
Sherman, M.Y.5
Morimoto, R.I.6
Massie, B.7
-
24
-
-
0036514504
-
Modelling neurodegenerative diseases in Drosophila: A fruitful approach?
-
Muqit M.M., Feany M.B. Modelling neurodegenerative diseases in Drosophila. a fruitful approach? Nat. Rev. Neurosci. 3:2002;237-243.
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 237-243
-
-
Muqit, M.M.1
Feany, M.B.2
-
25
-
-
0036301947
-
A decade of molecular studies of fragile X syndrome
-
O'Donnell W.T., Warren S.T. A decade of molecular studies of fragile X syndrome. Annu. Rev. Neurosci. 25:2002;315-338.
-
(2002)
Annu. Rev. Neurosci.
, vol.25
, pp. 315-338
-
-
O'Donnell, W.T.1
Warren, S.T.2
-
26
-
-
0036918690
-
Reduced FMR1 mRNA translation efficiency in fragile X patients with premutations
-
Primerano B., Tassone F., Hagerman R.J., Hagerman P., Amaldi F., Bagni C. Reduced FMR1 mRNA translation efficiency in fragile X patients with premutations. RNA. 8:2002;1482-1488.
-
(2002)
RNA
, vol.8
, pp. 1482-1488
-
-
Primerano, B.1
Tassone, F.2
Hagerman, R.J.3
Hagerman, P.4
Amaldi, F.5
Bagni, C.6
-
27
-
-
0036591663
-
Dominantly inherited, non-coding microsatellite expansion disorders
-
Ranum L.P., Day J.W. Dominantly inherited, non-coding microsatellite expansion disorders. Curr. Opin. Genet. Dev. 12:2002;266-271.
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 266-271
-
-
Ranum, L.P.1
Day, J.W.2
-
29
-
-
0005968048
-
Epidemiology
-
R.J. Treatment and Research, P.J. Hagerman and, & Hagerman. Baltimore, MD: The Johns Hopkins University Press. 136-168.pp
-
Sherman S.L. Epidemiology. Treatment and Research R.J., Hagerman and P.J., Hagerman Fragile X Syndrome. Diagnosis:2002;The Johns Hopkins University Press, Baltimore, MD. 136-168.pp.
-
(2002)
Fragile X Syndrome: Diagnosis
-
-
Sherman, S.L.1
-
30
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
Soto C. Unfolding the role of protein misfolding in neurodegenerative diseases. Nat. Rev. Neurosci. 4:2003;49-60.
-
(2003)
Nat. Rev. Neurosci.
, vol.4
, pp. 49-60
-
-
Soto, C.1
-
31
-
-
0033940157
-
Elevated levels of FMR1 mRNA in carrier males: A new mechanism of involvement in the fragile-X syndrome
-
Tassone F., Hagerman R.J., Taylor A.K., Gane L.W., Godfrey T.E., Hagerman P.J. Elevated levels of FMR1 mRNA in carrier males. a new mechanism of involvement in the fragile-X syndrome Am. J. Hum. Genet. 66:2000;6-15.
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 6-15
-
-
Tassone, F.1
Hagerman, R.J.2
Taylor, A.K.3
Gane, L.W.4
Godfrey, T.E.5
Hagerman, P.J.6
-
32
-
-
0032727617
-
Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70
-
Warrick J.M., Chan H.Y., Gray-Board G.L., Chai Y., Paulson H.L., Bonini N.M. Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70. Nat. Genet. 23:1999;425-428.
-
(1999)
Nat. Genet.
, vol.23
, pp. 425-428
-
-
Warrick, J.M.1
Chan, H.Y.2
Gray-Board, G.L.3
Chai, Y.4
Paulson, H.L.5
Bonini, N.M.6
-
33
-
-
18544392423
-
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila
-
Warrick J.M., Paulson H.L., Gray-Board G.L., Bui Q.T., Fischbeck K.H., Pittman R.N., Bonini N.M. Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila. Cell. 93:1998;939-949.
-
(1998)
Cell
, vol.93
, pp. 939-949
-
-
Warrick, J.M.1
Paulson, H.L.2
Gray-Board, G.L.3
Bui, Q.T.4
Fischbeck, K.H.5
Pittman, R.N.6
Bonini, N.M.7
-
34
-
-
0038025990
-
The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; Implications for the cerebellar tremor/ataxia syndrome
-
Willemsen R., Hoogeveen-Westerveld M., Reis S., Holstege J., Severijnen L.A., Nieuwenhuizen I.M., Schrier M., Van Unen L., Tassone F., Hoogeveen A.T.et al. The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome. Hum. Mol. Genet. 12:2003;949-959.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 949-959
-
-
Willemsen, R.1
Hoogeveen-Westerveld, M.2
Reis, S.3
Holstege, J.4
Severijnen, L.A.5
Nieuwenhuizen, I.M.6
Schrier, M.7
Van Unen, L.8
Tassone, F.9
Hoogeveen, A.T.10
-
35
-
-
0035930598
-
Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation
-
Zhou H., Li S.H., Li X.J. Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation. J. Biol. Chem. 276:2001;48417-48424.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48417-48424
-
-
Zhou, H.1
Li, S.H.2
Li, X.J.3
-
36
-
-
0036720019
-
Mouse and fly models of neurodegeneration
-
Zoghbi H.Y., Botas J. Mouse and fly models of neurodegeneration. Trends Genet. 18:2002;463-471.
-
(2002)
Trends Genet.
, vol.18
, pp. 463-471
-
-
Zoghbi, H.Y.1
Botas, J.2
|