Synaptic structure and function in transgenic APP mice

Annals of the New York Academy of Sciences

Volumn 924, Issue , 2000, Pages 39-41

  Ashe, Karen Hsiao ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Amyloid precursor protein; Synaptic structure (murine); Transgenic APP mice

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; COGNITION; CONFERENCE PAPER; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HIPPOCAMPUS; MAZE TEST; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PROTEIN EXPRESSION; SENILE PLAQUE; SYNAPTIC TRANSMISSION; TRANSGENIC MOUSE;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 0034502319     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb05558.x     Document Type: Conference Paper

References (8)

1. Correlative memory deficits, Aβ elevation, and amyloid placques in transgenic mice
2. APPSw transgenic mice develop age-related Aβ deposits and neuropil abnormalities, but no neuronal loss in CA1
3. Microglial response to amyloid plaques in APPsw transgenic mice
4. Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress
5. Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: A chronic oxidative paradigm for testing antioxidant therapies in vivo
6. Glutamate receptor dysregulation in the hippocampus of transgenic mice carrying mutated human amyloid precursor protein
7. Impaired synaptic plasticity and learning in aged amyloid precursor protein-transgenic mice