-
1
-
-
0033543566
-
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene
-
Alam J., Stewart D., Touchard C., Boinapally S., Choi A.M.K., and Cook J.L. Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene. J Biol Chem 274 (1999) 26071-26078
-
(1999)
J Biol Chem
, vol.274
, pp. 26071-26078
-
-
Alam, J.1
Stewart, D.2
Touchard, C.3
Boinapally, S.4
Choi, A.M.K.5
Cook, J.L.6
-
2
-
-
0034623211
-
Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor
-
Alam J., Wicks C., Stewart D., Gong P., Touchard C., Otterbein S., et al. Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor. J Biol Chem 275 (2000) 27694-27702
-
(2000)
J Biol Chem
, vol.275
, pp. 27694-27702
-
-
Alam, J.1
Wicks, C.2
Stewart, D.3
Gong, P.4
Touchard, C.5
Otterbein, S.6
-
3
-
-
0037377144
-
Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2
-
Alam J., Killeen E., Gong P., Naquin R., Hu B., Stewart D., et al. Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2. Am J Physiol Renal Physiol 284 (2003) F743-F752
-
(2003)
Am J Physiol Renal Physiol
, vol.284
-
-
Alam, J.1
Killeen, E.2
Gong, P.3
Naquin, R.4
Hu, B.5
Stewart, D.6
-
4
-
-
0027243681
-
Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein
-
Andrews N.C., Erdjument-Bromage H., Davidson M.B., Tempst P., and Orkin S.H. Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein. Nature 362 (1993) 722-728
-
(1993)
Nature
, vol.362
, pp. 722-728
-
-
Andrews, N.C.1
Erdjument-Bromage, H.2
Davidson, M.B.3
Tempst, P.4
Orkin, S.H.5
-
5
-
-
20444456655
-
Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2
-
Anwar A.A., Li F.Y.L., Leake D.S., Ishii T., Mann G.E., and Siow R.C.M. Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2. Free Radic Biol Med 39 (2005) 227-236
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 227-236
-
-
Anwar, A.A.1
Li, F.Y.L.2
Leake, D.S.3
Ishii, T.4
Mann, G.E.5
Siow, R.C.M.6
-
6
-
-
0035875447
-
Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust
-
Aoki Y., Sato H., Nishimura N., Takahashi S., Itoh K., and Yamamoto M. Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust. Toxicol Appl Pharmacol 173 (2001) 154-160
-
(2001)
Toxicol Appl Pharmacol
, vol.173
, pp. 154-160
-
-
Aoki, Y.1
Sato, H.2
Nishimura, N.3
Takahashi, S.4
Itoh, K.5
Yamamoto, M.6
-
7
-
-
15444363241
-
i2 gene promoter through nuclear factor-κB and antioxidant response elements
-
i2 gene promoter through nuclear factor-κB and antioxidant response elements. J Biol Chem 280 (2005) 9786-9795
-
(2005)
J Biol Chem
, vol.280
, pp. 9786-9795
-
-
Arinze, I.J.1
Kawai, Y.2
-
8
-
-
7444271583
-
BRCA1 induces antioxidant gene expression and resistance to oxidative stress
-
Bae I., Fan S., Meng Q., Rih J.K., Kim H.J., Kang H.J., et al. BRCA1 induces antioxidant gene expression and resistance to oxidative stress. Cancer Res 64 (2004) 7893-7909
-
(2004)
Cancer Res
, vol.64
, pp. 7893-7909
-
-
Bae, I.1
Fan, S.2
Meng, Q.3
Rih, J.K.4
Kim, H.J.5
Kang, H.J.6
-
9
-
-
11344292584
-
Smad3-ATF3 signaling mediates TGF-β suppression of genes encoding Phase II detoxifying proteins
-
Bakin A.V., Stourman N.V., Sekhar K.R., Rinehart C., Yan X., Meredith M.J., et al. Smad3-ATF3 signaling mediates TGF-β suppression of genes encoding Phase II detoxifying proteins. Free Radic Biol Med 38 (2005) 375-387
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 375-387
-
-
Bakin, A.V.1
Stourman, N.V.2
Sekhar, K.R.3
Rinehart, C.4
Yan, X.5
Meredith, M.J.6
-
10
-
-
0037569694
-
Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
-
Balogun E., Hoque M., Gong P., Killeen E., Green C.J., Foresti R., et al. Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element. Biochem J 371 (2003) 887-895
-
(2003)
Biochem J
, vol.371
, pp. 887-895
-
-
Balogun, E.1
Hoque, M.2
Gong, P.3
Killeen, E.4
Green, C.J.5
Foresti, R.6
-
11
-
-
20344405468
-
The GI-GPx gene is a target for Nrf2
-
Banning A., Deubel S., Kluth D., Zhou Z., and Brigelius-Flohé R. The GI-GPx gene is a target for Nrf2. Mol Cell Biol 25 (2005) 4914-4923
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4914-4923
-
-
Banning, A.1
Deubel, S.2
Kluth, D.3
Zhou, Z.4
Brigelius-Flohé, R.5
-
12
-
-
0242666198
-
40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression
-
40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression. J Biol Chem 278 (2003) 44675-44682
-
(2003)
J Biol Chem
, vol.278
, pp. 44675-44682
-
-
Bloom, D.A.1
Jaiswal, A.K.2
-
13
-
-
0037192626
-
Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene
-
Bloom D., Dhakshinamoorthy S., and Jaiswal A.K. Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene. Oncogene 21 (2002) 2191-2200
-
(2002)
Oncogene
, vol.21
, pp. 2191-2200
-
-
Bloom, D.1
Dhakshinamoorthy, S.2
Jaiswal, A.K.3
-
14
-
-
0036318224
-
Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound
-
Braun S., Hanselmann C., Gassmann M.G., auf dem Keller U., Born-Berclaz C., Chan K., et al. Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound. Mol Cell Biol 22 (2002) 5492-5505
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5492-5505
-
-
Braun, S.1
Hanselmann, C.2
Gassmann, M.G.3
auf dem Keller, U.4
Born-Berclaz, C.5
Chan, K.6
-
15
-
-
0037767747
-
Nitric oxide stimulates Nrf2 nuclear translocation in vascular endothelium
-
Buckley B.J., Marshall Z.M., and Whorton A.R. Nitric oxide stimulates Nrf2 nuclear translocation in vascular endothelium. Biochem Biophys Res Commun 307 (2003) 973-979
-
(2003)
Biochem Biophys Res Commun
, vol.307
, pp. 973-979
-
-
Buckley, B.J.1
Marshall, Z.M.2
Whorton, A.R.3
-
16
-
-
11844253848
-
Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription
-
Calkins M.J., Jakel R.J., Johnson D.A., Chan K., Kan Y.W., and Johnson J.A. Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription. Proc Natl Acad Sci USA 102 (2005) 244-249
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 244-249
-
-
Calkins, M.J.1
Jakel, R.J.2
Johnson, D.A.3
Chan, K.4
Kan, Y.W.5
Johnson, J.A.6
-
17
-
-
0028247214
-
Cloning and functional characterization of LCR-F1: a bZIP transcription factor that activates erythroid-specific, human globin gene expression
-
Caterina J.J., Donze D., Sun C.W., Ciavatta D.J., and Townes T.M. Cloning and functional characterization of LCR-F1: a bZIP transcription factor that activates erythroid-specific, human globin gene expression. Nucleic Acids Res 22 (1994) 2383-2391
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 2383-2391
-
-
Caterina, J.J.1
Donze, D.2
Sun, C.W.3
Ciavatta, D.J.4
Townes, T.M.5
-
18
-
-
13044304201
-
Nrf2 is essential for protection against acute pulmonary injury in mice
-
Chan K., and Kan Y.W. Nrf2 is essential for protection against acute pulmonary injury in mice. Proc Natl Acad Sci USA 96 (1999) 12731-12736
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12731-12736
-
-
Chan, K.1
Kan, Y.W.2
-
19
-
-
0034672595
-
Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein
-
Chan J.Y., and Kwong M. Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein. Biochim Biophys Acta 1517 (2000) 19-26
-
(2000)
Biochim Biophys Acta
, vol.1517
, pp. 19-26
-
-
Chan, J.Y.1
Kwong, M.2
-
20
-
-
0027360226
-
Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast
-
Chan J.Y., Han X.L., and Kan Y.W. Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast. Proc Natl Acad Sci USA 90 (1993) 11371-11375
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11371-11375
-
-
Chan, J.Y.1
Han, X.L.2
Kan, Y.W.3
-
21
-
-
0030451213
-
NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development
-
Chan K., Lu R., Chang J.C., and Kan Y.W. NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development. Proc Natl Acad Sci USA 93 (1996) 13943-13948
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13943-13948
-
-
Chan, K.1
Lu, R.2
Chang, J.C.3
Kan, Y.W.4
-
22
-
-
0032536783
-
Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice
-
Chan J.Y., Kwong M., Lu R., Chang J., Wang B., Yen T.S.B., et al. Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice. EMBO J 17 (1998) 1779-1787
-
(1998)
EMBO J
, vol.17
, pp. 1779-1787
-
-
Chan, J.Y.1
Kwong, M.2
Lu, R.3
Chang, J.4
Wang, B.5
Yen, T.S.B.6
-
23
-
-
0035836698
-
An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen
-
Chan K., Han X.D., and Kan Y.W. An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen. Proc Natl Acad Sci USA 98 (2001) 4611-4616
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4611-4616
-
-
Chan, K.1
Han, X.D.2
Kan, Y.W.3
-
24
-
-
0037101768
-
Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice
-
Chanas S.A., Jiang Q., McMahon M., McWalter G.K., McLellan L.I., Elcombe C.R., et al. Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice. Biochem J 365 (2002) 405-416
-
(2002)
Biochem J
, vol.365
, pp. 405-416
-
-
Chanas, S.A.1
Jiang, Q.2
McMahon, M.3
McWalter, G.K.4
McLellan, L.I.5
Elcombe, C.R.6
-
25
-
-
0037428445
-
Laminar flow induction of antioxidant response element-mediated genes in endothelial cells. A novel anti-inflammatory mechanism
-
Chen X.L., Varner S.E., Rao A.S., Grey J.Y., Thomas S., Cook C.K., et al. Laminar flow induction of antioxidant response element-mediated genes in endothelial cells. A novel anti-inflammatory mechanism. J Biol Chem 278 (2003) 703-711
-
(2003)
J Biol Chem
, vol.278
, pp. 703-711
-
-
Chen, X.L.1
Varner, S.E.2
Rao, A.S.3
Grey, J.Y.4
Thomas, S.5
Cook, C.K.6
-
26
-
-
0036007313
-
Role of NRF2 in protection against hyperoxic lung injury in mice
-
Cho H.Y., Jedlicka A.E., Reddy S.P.M., Kensler T.W., Yamamoto M., Zhang L.Y., et al. Role of NRF2 in protection against hyperoxic lung injury in mice. Am J Respir Cell Mol Biol 26 (2002) 175-182
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 175-182
-
-
Cho, H.Y.1
Jedlicka, A.E.2
Reddy, S.P.M.3
Kensler, T.W.4
Yamamoto, M.5
Zhang, L.Y.6
-
27
-
-
0036006792
-
Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene
-
Cho H.Y., Jedlicka A.E., Reddy S.P.M., Zhang L.Y., Kensler T.W., and Kleeberger S.R. Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene. Am J Respir Cell Mol Biol 26 (2002) 42-51
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 42-51
-
-
Cho, H.Y.1
Jedlicka, A.E.2
Reddy, S.P.M.3
Zhang, L.Y.4
Kensler, T.W.5
Kleeberger, S.R.6
-
28
-
-
11444261268
-
Gene expression profiling of NRF2-mediated protection against oxidative injury
-
Cho H.Y., Reddy S.P., DeBiase A., Yamamoto M., and Kleeberger S.R. Gene expression profiling of NRF2-mediated protection against oxidative injury. Free Radic Biol Med 38 (2005) 325-343
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 325-343
-
-
Cho, H.Y.1
Reddy, S.P.2
DeBiase, A.3
Yamamoto, M.4
Kleeberger, S.R.5
-
29
-
-
0029839794
-
Oxidative stress induces the levels of a MafG homolog in hamster HA-1 cells
-
Crawford D.R., Leahy K.P., Wang Y., Schools G.P., Kochheiser J.C., and Davies K.J.A. Oxidative stress induces the levels of a MafG homolog in hamster HA-1 cells. Free Radic Biol Med 21 (1996) 521-525
-
(1996)
Free Radic Biol Med
, vol.21
, pp. 521-525
-
-
Crawford, D.R.1
Leahy, K.P.2
Wang, Y.3
Schools, G.P.4
Kochheiser, J.C.5
Davies, K.J.A.6
-
30
-
-
2442542312
-
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
-
Cullinan S.B., and Diehl J.A. PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. J Biol Chem 279 (2004) 20108-20117
-
(2004)
J Biol Chem
, vol.279
, pp. 20108-20117
-
-
Cullinan, S.B.1
Diehl, J.A.2
-
31
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
Cullinan S.B., Zhang D., Hannink M., Arvisais E., Kaufman R.J., and Diehl J.A. Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol Cell Biol 23 (2003) 7198-7209
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
32
-
-
4544294365
-
The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase
-
Cullinan S.B., Gordan J.D., Jin J., Harper J.W., and Diehl J.A. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase. Mol Cell Biol 24 (2004) 8477-8486
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8477-8486
-
-
Cullinan, S.B.1
Gordan, J.D.2
Jin, J.3
Harper, J.W.4
Diehl, J.A.5
-
33
-
-
1842453034
-
Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus
-
Derjuga A., Gourley T.S., Holm T.M., Heng H.H.Q., Shivdasani R.A., Ahmed R., et al. Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus. Mol Cell Biol 24 (2004) 3286-3294
-
(2004)
Mol Cell Biol
, vol.24
, pp. 3286-3294
-
-
Derjuga, A.1
Gourley, T.S.2
Holm, T.M.3
Heng, H.H.Q.4
Shivdasani, R.A.5
Ahmed, R.6
-
34
-
-
18844454763
-
Utility of siRNA against Keap1 as a strategy to stimulate a cancer chemopreventive phenotype
-
Devling T.W.P., Lindsay C.D., McLellan L.I., McMahon M., and Hayes J.D. Utility of siRNA against Keap1 as a strategy to stimulate a cancer chemopreventive phenotype. Proc Natl Acad Sci USA 102 (2005) 7280-7285
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 7280-7285
-
-
Devling, T.W.P.1
Lindsay, C.D.2
McLellan, L.I.3
McMahon, M.4
Hayes, J.D.5
-
35
-
-
0034704137
-
Small maf (MafG and MafK) proteins negatively regulate antioxidant response element-mediated expression and antioxidant induction of the NAD(P)H:Quinone oxidoreductase1 gene
-
Dhakshinamoorthy S., and Jaiswal A.K. Small maf (MafG and MafK) proteins negatively regulate antioxidant response element-mediated expression and antioxidant induction of the NAD(P)H:Quinone oxidoreductase1 gene. J Biol Chem 275 (2000) 40134-40141
-
(2000)
J Biol Chem
, vol.275
, pp. 40134-40141
-
-
Dhakshinamoorthy, S.1
Jaiswal, A.K.2
-
36
-
-
0037043822
-
c-Maf negatively regulates ARE-mediated detoxifying enzyme genes expression and anti-oxidant induction
-
Dhakshinamoorthy S., and Jaiswal A.K. c-Maf negatively regulates ARE-mediated detoxifying enzyme genes expression and anti-oxidant induction. Oncogene 21 (2002) 5301-5312
-
(2002)
Oncogene
, vol.21
, pp. 5301-5312
-
-
Dhakshinamoorthy, S.1
Jaiswal, A.K.2
-
37
-
-
2442535969
-
Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells
-
Dhakshinamoorthy S., and Porter A.G. Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells. J Biol Chem 279 (2004) 20096-20107
-
(2004)
J Biol Chem
, vol.279
, pp. 20096-20107
-
-
Dhakshinamoorthy, S.1
Porter, A.G.2
-
38
-
-
0035853101
-
Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups
-
Dinkova-Kostova A.T., Massiah M.A., Bozak R.E., Hicks R.J., and Talalay P. Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups. Proc Natl Acad Sci USA 98 (2001) 3404-3409
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3404-3409
-
-
Dinkova-Kostova, A.T.1
Massiah, M.A.2
Bozak, R.E.3
Hicks, R.J.4
Talalay, P.5
-
39
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
Dinkova-Kostova A.T., Holtzclaw W.D., Cole R.N., Itoh K., Wakabayashi N., Katoh Y., et al. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc Natl Acad Sci USA 99 (2002) 11908-11913
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
-
40
-
-
18244377997
-
Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein
-
Dinkova-Kostova A.T., Holtzclaw W.D., and Wakabayashi N. Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein. Biochemistry 44 (2005) 6889-6899
-
(2005)
Biochemistry
, vol.44
, pp. 6889-6899
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Wakabayashi, N.3
-
41
-
-
20144383831
-
Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress
-
Dinkova-Kostova A.T., Liby K.T., Stephenson K.K., Holtzclaw W.D., Gao X., Suh N., et al. Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress. Proc Natl Acad Sci USA 102 (2005) 4584-4589
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4584-4589
-
-
Dinkova-Kostova, A.T.1
Liby, K.T.2
Stephenson, K.K.3
Holtzclaw, W.D.4
Gao, X.5
Suh, N.6
-
42
-
-
0033549896
-
Ubiquitin pathway: another link in the polyubiquitin chain?
-
Dubiel W., and Gordon C. Ubiquitin pathway: another link in the polyubiquitin chain?. Curr Biol 9 (1999) R554-R557
-
(1999)
Curr Biol
, vol.9
-
-
Dubiel, W.1
Gordon, C.2
-
43
-
-
22544464124
-
Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2
-
Eggler A.L., Liu G., Pezzuto J.M., van Breemen R.B., and Mesecar A.D. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2. Proc Natl Acad Sci USA 102 (2005) 10070-10075
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10070-10075
-
-
Eggler, A.L.1
Liu, G.2
Pezzuto, J.M.3
van Breemen, R.B.4
Mesecar, A.D.5
-
44
-
-
0035153227
-
High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes
-
Enomoto A., Itoh K., Nagayoshi E., Haruta J., Kimura T., O'Connor T., et al. High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes. Toxicol Sci 59 (2001) 169-177
-
(2001)
Toxicol Sci
, vol.59
, pp. 169-177
-
-
Enomoto, A.1
Itoh, K.2
Nagayoshi, E.3
Haruta, J.4
Kimura, T.5
O'Connor, T.6
-
45
-
-
0037163092
-
Identification of a variant antioxidant response element in the promoter of the human glutamate-cysteine ligase modifier subunit gene. Revision of the ARE consensus sequence
-
Erickson A.M., Nevarea Z., Gipp J.J., and Mulcahy R.T. Identification of a variant antioxidant response element in the promoter of the human glutamate-cysteine ligase modifier subunit gene. Revision of the ARE consensus sequence. J Biol Chem 277 (2002) 30730-30737
-
(2002)
J Biol Chem
, vol.277
, pp. 30730-30737
-
-
Erickson, A.M.1
Nevarea, Z.2
Gipp, J.J.3
Mulcahy, R.T.4
-
46
-
-
0037188518
-
Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors
-
Fahey J.W., Haristoy X., Dolan P.M., Kensler T.W., Scholtus I., Stephenson K.K., et al. Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors. Proc Natl Acad Sci USA 99 (2002) 7610-7615
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 7610-7615
-
-
Fahey, J.W.1
Haristoy, X.2
Dolan, P.M.3
Kensler, T.W.4
Scholtus, I.5
Stephenson, K.K.6
-
47
-
-
0030995597
-
The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development
-
Farmer S.C., Sun C.W., Winnier G.E., Hogan B.L.M., and Townes T.M. The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development. Genes Dev 11 (1997) 786-798
-
(1997)
Genes Dev
, vol.11
, pp. 786-798
-
-
Farmer, S.C.1
Sun, C.W.2
Winnier, G.E.3
Hogan, B.L.M.4
Townes, T.M.5
-
48
-
-
0025806510
-
Transcriptional regulation of the rat NAD(P)H:quinone reductase gene. Identification of regulatory elements controlling basal level expression and inducible expression by planar aromatic compounds and phenolic antioxidants
-
Favreau L.V., and Pickett C.B. Transcriptional regulation of the rat NAD(P)H:quinone reductase gene. Identification of regulatory elements controlling basal level expression and inducible expression by planar aromatic compounds and phenolic antioxidants. J Biol Chem 266 (1991) 4556-4561
-
(1991)
J Biol Chem
, vol.266
, pp. 4556-4561
-
-
Favreau, L.V.1
Pickett, C.B.2
-
49
-
-
0025145723
-
Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element
-
Friling R.S., Bensimon A., Tichauer Y., and Daniel V. Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element. Proc Natl Acad Sci USA 87 (1990) 6258-6262
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6258-6262
-
-
Friling, R.S.1
Bensimon, A.2
Tichauer, Y.3
Daniel, V.4
-
50
-
-
0026571238
-
Two adjacent AP-1-like binding sites form the electrophile-responsive element of the murine glutathione S-transferase Ya subunit gene
-
Friling R.S., Bergelson S., and Daniel V. Two adjacent AP-1-like binding sites form the electrophile-responsive element of the murine glutathione S-transferase Ya subunit gene. Proc Natl Acad Sci USA 89 (1992) 668-672
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 668-672
-
-
Friling, R.S.1
Bergelson, S.2
Daniel, V.3
-
51
-
-
12044260178
-
Two new members of the maf oncogene family, mafK and mafF, encode nuclear b-Zip proteins lacking putative trans-activator domain
-
Fujiwara K.T., Kataoka K., and Nishizawa M. Two new members of the maf oncogene family, mafK and mafF, encode nuclear b-Zip proteins lacking putative trans-activator domain. Oncogene 8 (1993) 2371-2380
-
(1993)
Oncogene
, vol.8
, pp. 2371-2380
-
-
Fujiwara, K.T.1
Kataoka, K.2
Nishizawa, M.3
-
52
-
-
11144264663
-
BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the cullin 3-Roc1 ligase
-
Furukawa M., and Xiong Y. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the cullin 3-Roc1 ligase. Mol Cell Biol 25 (2005) 162-171
-
(2005)
Mol Cell Biol
, vol.25
, pp. 162-171
-
-
Furukawa, M.1
Xiong, Y.2
-
53
-
-
3142721782
-
Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage
-
Gao X., and Talalay P. Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage. Proc Natl Acad Sci USA 101 (2004) 10446-10451
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10446-10451
-
-
Gao, X.1
Talalay, P.2
-
54
-
-
0141534255
-
Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein 1 in mouse embryo fibroblasts
-
Hayashi A., Suzuki H., Itoh K., Yamamoto M., and Sugiyama Y. Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein 1 in mouse embryo fibroblasts. Biochem Biophys Res Commun 310 (2003) 824-829
-
(2003)
Biochem Biophys Res Commun
, vol.310
, pp. 824-829
-
-
Hayashi, A.1
Suzuki, H.2
Itoh, K.3
Yamamoto, M.4
Sugiyama, Y.5
-
55
-
-
0035877643
-
Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation
-
He C.H., Gong P., Hu B., Stewart D., Choi M.E., Choi A.M.K., et al. Identification of activating transcription factor 4 (ATF4) as an Nrf2-interacting protein. Implication for heme oxygenase-1 gene regulation. J Biol Chem 276 (2001) 20858-20865
-
(2001)
J Biol Chem
, vol.276
, pp. 20858-20865
-
-
He, C.H.1
Gong, P.2
Hu, B.3
Stewart, D.4
Choi, M.E.5
Choi, A.M.K.6
-
56
-
-
0037448015
-
EPR imaging of reducing activity in Nrf2 transcriptional factor-deficient mice
-
Hirayama A., Yoh K., Nagase S., Ueda A., Itoh K., Morito N., et al. EPR imaging of reducing activity in Nrf2 transcriptional factor-deficient mice. Free Radic Biol Med 34 (2003) 1236-1242
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 1236-1242
-
-
Hirayama, A.1
Yoh, K.2
Nagase, S.3
Ueda, A.4
Itoh, K.5
Morito, N.6
-
57
-
-
16844375366
-
Ultraviolet A irradiation induces NF-E2-related factor 2 activation in dermal fibroblasts: protective role in UVA-induced apoptosis
-
Hirota A., Kawachi Y., Itoh K., Nakamura Y., Xu X., Banno T., et al. Ultraviolet A irradiation induces NF-E2-related factor 2 activation in dermal fibroblasts: protective role in UVA-induced apoptosis. J Invest Dermatol 124 (2005) 825-832
-
(2005)
J Invest Dermatol
, vol.124
, pp. 825-832
-
-
Hirota, A.1
Kawachi, Y.2
Itoh, K.3
Nakamura, Y.4
Xu, X.5
Banno, T.6
-
58
-
-
9644272830
-
Protection against electrophile and oxidative stress by induction of phase 2 genes: the quest for the elusive sensor that responds to inducers
-
Holtzclaw W.D., Dinkova-Kostova A.T., and Talalay P. Protection against electrophile and oxidative stress by induction of phase 2 genes: the quest for the elusive sensor that responds to inducers. Adv Enzyme Regul 44 (2004) 335-367
-
(2004)
Adv Enzyme Regul
, vol.44
, pp. 335-367
-
-
Holtzclaw, W.D.1
Dinkova-Kostova, A.T.2
Talalay, P.3
-
59
-
-
24744453945
-
Specific patterns of electrophile adduction trigger keap1 ubiquitination and NRF2 activation
-
Hong F., Sekhar K.R., Freeman M.L., and Liebler D.C. Specific patterns of electrophile adduction trigger keap1 ubiquitination and NRF2 activation. J Biol Chem 280 (2005) 31768-31775
-
(2005)
J Biol Chem
, vol.280
, pp. 31768-31775
-
-
Hong, F.1
Sekhar, K.R.2
Freeman, M.L.3
Liebler, D.C.4
-
60
-
-
22844450096
-
Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells
-
Hosoya T., Maruyama A., Kang M.I., Kawatani Y., Shibata T., Uchida K., et al. Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells. J Biol Chem 280 (2005) 27244-27250
-
(2005)
J Biol Chem
, vol.280
, pp. 27244-27250
-
-
Hosoya, T.1
Maruyama, A.2
Kang, M.I.3
Kawatani, Y.4
Shibata, T.5
Uchida, K.6
-
61
-
-
0033731182
-
Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2
-
Huang H.C., Nguyen T., and Pickett C.B. Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2. Proc Natl Acad Sci USA 97 (2000) 12475-12480
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 12475-12480
-
-
Huang, H.C.1
Nguyen, T.2
Pickett, C.B.3
-
62
-
-
0037044791
-
Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
-
Huang H.C., Nguyen T., and Pickett C.B. Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription. J Biol Chem 277 (2002) 42769-42774
-
(2002)
J Biol Chem
, vol.277
, pp. 42769-42774
-
-
Huang, H.C.1
Nguyen, T.2
Pickett, C.B.3
-
63
-
-
0034710173
-
Cloning and characterization of the proximal promoter region of the mouse glutamate-l-cysteine ligase regulatory subunit gene
-
Hudson F.N., and Kavanagh T.J. Cloning and characterization of the proximal promoter region of the mouse glutamate-l-cysteine ligase regulatory subunit gene. Biochim Biophys Acta 1492 (2000) 447-451
-
(2000)
Biochim Biophys Acta
, vol.1492
, pp. 447-451
-
-
Hudson, F.N.1
Kavanagh, T.J.2
-
64
-
-
0028118492
-
Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins
-
Igarashi K., Kataoka K., Itoh K., Hayashi N., Nishizawa M., and Yamamoto M. Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins. Nature 367 (1994) 568-572
-
(1994)
Nature
, vol.367
, pp. 568-572
-
-
Igarashi, K.1
Kataoka, K.2
Itoh, K.3
Hayashi, N.4
Nishizawa, M.5
Yamamoto, M.6
-
65
-
-
0028937626
-
Activity and expression of murine small Maf family protein MafK
-
Igarashi K., Itoh K., Motohashi H., Hayashi N., Matuzaki Y., Nakauchi H., et al. Activity and expression of murine small Maf family protein MafK. J Biol Chem 270 (1995) 7615-7624
-
(1995)
J Biol Chem
, vol.270
, pp. 7615-7624
-
-
Igarashi, K.1
Itoh, K.2
Motohashi, H.3
Hayashi, N.4
Matuzaki, Y.5
Nakauchi, H.6
-
66
-
-
0032496139
-
Multivalent DNA binding complex generated by small Maf and Bach1 as a possible biochemical basis for β-globin locus control region complex
-
Igarashi K., Hoshino H., Muto A., Suwabe N., Nishikawa S., Nakauchi H., et al. Multivalent DNA binding complex generated by small Maf and Bach1 as a possible biochemical basis for β-globin locus control region complex. J Biol Chem 273 (1998) 11783-11790
-
(1998)
J Biol Chem
, vol.273
, pp. 11783-11790
-
-
Igarashi, K.1
Hoshino, H.2
Muto, A.3
Suwabe, N.4
Nishikawa, S.5
Nakauchi, H.6
-
67
-
-
4644328941
-
Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis
-
Iida K., Itoh K., Kumagai Y., Oyasu R., Hattori K., Kawai K., et al. Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis. Cancer Res 64 (2004) 6424-6431
-
(2004)
Cancer Res
, vol.64
, pp. 6424-6431
-
-
Iida, K.1
Itoh, K.2
Kumagai, Y.3
Oyasu, R.4
Hattori, K.5
Kawai, K.6
-
68
-
-
29244473882
-
Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema
-
Iizuka T., Ishii Y., Itoh K., Kiwamoto T., Kimura T., Matsuno Y., et al. Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema. Genes Cells 10 (2005) 1113-1125
-
(2005)
Genes Cells
, vol.10
, pp. 1113-1125
-
-
Iizuka, T.1
Ishii, Y.2
Itoh, K.3
Kiwamoto, T.4
Kimura, T.5
Matsuno, Y.6
-
69
-
-
0034693219
-
Suppression of rat thromboxane synthase gene transcription by peroxisome proliferator-activated receptor γ in macrophages via an interaction with NRF2
-
Ikeda Y., Sugawara A., Taniyama Y., Uruno A., Igarashi K., Arima S., et al. Suppression of rat thromboxane synthase gene transcription by peroxisome proliferator-activated receptor γ in macrophages via an interaction with NRF2. J Biol Chem 275 (2000) 33142-33150
-
(2000)
J Biol Chem
, vol.275
, pp. 33142-33150
-
-
Ikeda, Y.1
Sugawara, A.2
Taniyama, Y.3
Uruno, A.4
Igarashi, K.5
Arima, S.6
-
70
-
-
0034717329
-
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
-
Ishii T., Itoh K., Takahashi S., Sato H., Yanagawa T., Katoh Y., et al. Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J Biol Chem 275 (2000) 16023-16029
-
(2000)
J Biol Chem
, vol.275
, pp. 16023-16029
-
-
Ishii, T.1
Itoh, K.2
Takahashi, S.3
Sato, H.4
Yanagawa, T.5
Katoh, Y.6
-
71
-
-
1642396537
-
Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal
-
Ishii T., Itoh K., Ruiz E., Leake D.S., Unoki H., Yamamoto M., et al. Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal. Circ Res 94 (2004) 609-616
-
(2004)
Circ Res
, vol.94
, pp. 609-616
-
-
Ishii, T.1
Itoh, K.2
Ruiz, E.3
Leake, D.S.4
Unoki, H.5
Yamamoto, M.6
-
72
-
-
27744450995
-
Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema
-
Ishii Y., Itoh K., Morishima Y., Kimura T., Kiwamoto T., Iizuka T., et al. Transcription factor Nrf2 plays a pivotal role in protection against elastase-induced pulmonary inflammation and emphysema. J Immunol 175 (2005) 6968-6975
-
(2005)
J Immunol
, vol.175
, pp. 6968-6975
-
-
Ishii, Y.1
Itoh, K.2
Morishima, Y.3
Kimura, T.4
Kiwamoto, T.5
Iizuka, T.6
-
73
-
-
0029043995
-
Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins
-
Itoh K., Igarashi K., Hayashi N., Nishizawa M., and Yamamoto M. Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins. Mol Cell Biol 15 (1995) 4184-4193
-
(1995)
Mol Cell Biol
, vol.15
, pp. 4184-4193
-
-
Itoh, K.1
Igarashi, K.2
Hayashi, N.3
Nishizawa, M.4
Yamamoto, M.5
-
74
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh K., Chiba T., Takahashi S., Ishii T., Igarashi K., Katoh Y., et al. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun 236 (1997) 313-322
-
(1997)
Biochem Biophys Res Commun
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
-
75
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J.D., et al. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 13 (1999) 76-86
-
(1999)
Genes Dev
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
-
76
-
-
12444257799
-
Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles
-
Itoh K., Wakabayashi N., Katoh Y., Ishii T., O'Connor T., and Yamamoto M. Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles. Genes Cells 8 (2003) 379-391
-
(2003)
Genes Cells
, vol.8
, pp. 379-391
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
O'Connor, T.5
Yamamoto, M.6
-
78
-
-
23844475091
-
Nuclear import and export signals in control of Nrf2
-
Jain A.K., Bloom D.A., and Jaiswal A.K. Nuclear import and export signals in control of Nrf2. J Biol Chem 280 (2005) 29158-29168
-
(2005)
J Biol Chem
, vol.280
, pp. 29158-29168
-
-
Jain, A.K.1
Bloom, D.A.2
Jaiswal, A.K.3
-
79
-
-
0037077204
-
1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1
-
1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1. J Biol Chem 277 (2002) 21158-21166
-
(2002)
J Biol Chem
, vol.277
, pp. 21158-21166
-
-
Jardine, H.1
MacNee, W.2
Donaldson, K.3
Rahman, I.4
-
80
-
-
0036436025
-
Peroxynitrite activates NF-E2-related factor 2/antioxidant response element through the pathway of phosphatidylinositol 3-kinase: the role of nitric oxide synthase in rat glutathione S-transferase A2 induction
-
Kang K.W., Choi S.H., and Kim S.G. Peroxynitrite activates NF-E2-related factor 2/antioxidant response element through the pathway of phosphatidylinositol 3-kinase: the role of nitric oxide synthase in rat glutathione S-transferase A2 induction. Nitric Oxide 7 (2002) 244-253
-
(2002)
Nitric Oxide
, vol.7
, pp. 244-253
-
-
Kang, K.W.1
Choi, S.H.2
Kim, S.G.3
-
81
-
-
0036840585
-
Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress
-
Kang K.W., Lee S.J., Park J.W., and Kim S.G. Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress. Mol Pharmacol 62 (2002) 1001-1010
-
(2002)
Mol Pharmacol
, vol.62
, pp. 1001-1010
-
-
Kang, K.W.1
Lee, S.J.2
Park, J.W.3
Kim, S.G.4
-
82
-
-
0037245333
-
Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/enhancer binding protein β activation in the induction of glutathione S-transferase by oltipraz
-
Kang K.W., Cho I.J., Lee C.H., and Kim S.G. Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/enhancer binding protein β activation in the induction of glutathione S-transferase by oltipraz. J Natl Cancer Inst 95 (2003) 53-66
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 53-66
-
-
Kang, K.W.1
Cho, I.J.2
Lee, C.H.3
Kim, S.G.4
-
83
-
-
0037357385
-
Activation of CCAAT/enhancer-binding protein β by 2′-amino-3′-methoxyflavone (PD98059) leads to the induction of glutathione S-transferase A2
-
Kang K.W., Park E.Y., and Kim S.G. Activation of CCAAT/enhancer-binding protein β by 2′-amino-3′-methoxyflavone (PD98059) leads to the induction of glutathione S-transferase A2. Carcinogenesis 24 (2003) 475-482
-
(2003)
Carcinogenesis
, vol.24
, pp. 475-482
-
-
Kang, K.W.1
Park, E.Y.2
Kim, S.G.3
-
84
-
-
1242274394
-
Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes
-
Kang M.I., Kobayashi A., Wakabayashi N., Kim S.G., and Yamamoto M. Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes. Proc Natl Acad Sci USA 101 (2004) 2046-2051
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2046-2051
-
-
Kang, M.I.1
Kobayashi, A.2
Wakabayashi, N.3
Kim, S.G.4
Yamamoto, M.5
-
85
-
-
19944430116
-
Nuclear oncoprotein prothymosin α is a partner of Keap1: implications for expression of oxidative stress-protecting genes
-
Karapetian R.N., Evstafieva A.G., Abaeva I.S., Chichkova N.V., Filonov G.S., Rubtsov Y.P., et al. Nuclear oncoprotein prothymosin α is a partner of Keap1: implications for expression of oxidative stress-protecting genes. Mol Cell Biol 25 (2005) 1089-1099
-
(2005)
Mol Cell Biol
, vol.25
, pp. 1089-1099
-
-
Karapetian, R.N.1
Evstafieva, A.G.2
Abaeva, I.S.3
Chichkova, N.V.4
Filonov, G.S.5
Rubtsov, Y.P.6
-
86
-
-
0028986047
-
Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor
-
Kataoka K., Igarashi K., Itoh K., Fujiwara K.T., Noda M., Yamamoto M., et al. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Mol Cell Biol 15 (1995) 2180-2190
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2180-2190
-
-
Kataoka, K.1
Igarashi, K.2
Itoh, K.3
Fujiwara, K.T.4
Noda, M.5
Yamamoto, M.6
-
87
-
-
0035823540
-
Induction of cellular antioxidative stress genes through heterodimeric transcription factor Nrf2/small maf by antirheumatic gold(I) compounds
-
Kataoka K., Handa H., and Nishizawa M. Induction of cellular antioxidative stress genes through heterodimeric transcription factor Nrf2/small maf by antirheumatic gold(I) compounds. J Biol Chem 276 (2001) 34074-34081
-
(2001)
J Biol Chem
, vol.276
, pp. 34074-34081
-
-
Kataoka, K.1
Handa, H.2
Nishizawa, M.3
-
88
-
-
0034752461
-
Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
-
Katoh Y., Itoh K., Yoshida E., Miyagishi M., Fukamizu A., and Yamamoto M. Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription. Genes Cells 6 (2001) 857-868
-
(2001)
Genes Cells
, vol.6
, pp. 857-868
-
-
Katoh, Y.1
Itoh, K.2
Yoshida, E.3
Miyagishi, M.4
Fukamizu, A.5
Yamamoto, M.6
-
89
-
-
9944255781
-
Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome
-
Katoh Y., Iida K., Kang M.I., Kobayashi A., Mizukami M., Tong K.I., et al. Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome. Arch Biochem Biophys 433 (2005) 342-350
-
(2005)
Arch Biochem Biophys
, vol.433
, pp. 342-350
-
-
Katoh, Y.1
Iida, K.2
Kang, M.I.3
Kobayashi, A.4
Mizukami, M.5
Tong, K.I.6
-
90
-
-
0037313210
-
Small Maf compound mutants display central nervous system neuronal degeneration, aberrant transcription, and Bach protein mislocalization coincident with myoclonus and abnormal startle response
-
Katsuoka F., Motohashi H., Tamagawa Y., Kure S., Igarashi K., Engel J.D., et al. Small Maf compound mutants display central nervous system neuronal degeneration, aberrant transcription, and Bach protein mislocalization coincident with myoclonus and abnormal startle response. Mol Cell Biol 23 (2003) 1163-1174
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1163-1174
-
-
Katsuoka, F.1
Motohashi, H.2
Tamagawa, Y.3
Kure, S.4
Igarashi, K.5
Engel, J.D.6
-
91
-
-
14244256648
-
Nrf2 transcriptionally activates the mafG gene through an antioxidant response element
-
Katsuoka F., Motohashi H., Engel J.D., and Yamamoto M. Nrf2 transcriptionally activates the mafG gene through an antioxidant response element. J Biol Chem 280 (2005) 4483-4490
-
(2005)
J Biol Chem
, vol.280
, pp. 4483-4490
-
-
Katsuoka, F.1
Motohashi, H.2
Engel, J.D.3
Yamamoto, M.4
-
92
-
-
24344479164
-
Genetic evidence that small Maf proteins are essential for the activation of antioxidant response element-dependent genes
-
Katsuoka F., Motohashi H., Ishii T., Aburatani H., Engel J.D., and Yamamoto M. Genetic evidence that small Maf proteins are essential for the activation of antioxidant response element-dependent genes. Mol Cell Biol 25 (2005) 8044-8051
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8044-8051
-
-
Katsuoka, F.1
Motohashi, H.2
Ishii, T.3
Aburatani, H.4
Engel, J.D.5
Yamamoto, M.6
-
93
-
-
18144417838
-
Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPβ TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression
-
Ki S.H., Cho I.J., Choi D.W., and Kim S.G. Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPβ TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression. Mol Cell Biol 25 (2005) 4150-4165
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4150-4165
-
-
Ki, S.H.1
Cho, I.J.2
Choi, D.W.3
Kim, S.G.4
-
94
-
-
0035947654
-
Hemin-induced activation of the thioredoxin gene by Nrf2. a differential regulation of the antioxidant responsive element by a switch of its binding factors
-
Kim Y.C., Masutani H., Yamaguchi Y., Itoh K., Yamamoto M., and Yodoi J. Hemin-induced activation of the thioredoxin gene by Nrf2. a differential regulation of the antioxidant responsive element by a switch of its binding factors. J Biol Chem 276 (2001) 18399-18406
-
(2001)
J Biol Chem
, vol.276
, pp. 18399-18406
-
-
Kim, Y.C.1
Masutani, H.2
Yamaguchi, Y.3
Itoh, K.4
Yamamoto, M.5
Yodoi, J.6
-
95
-
-
0033525730
-
Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3
-
Kobayashi A., Ito E., Toki T., Kogame K., Takahashi S., Igarashi K., et al. Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3. J Biol Chem 274 (1999) 6443-6452
-
(1999)
J Biol Chem
, vol.274
, pp. 6443-6452
-
-
Kobayashi, A.1
Ito, E.2
Toki, T.3
Kogame, K.4
Takahashi, S.5
Igarashi, K.6
-
96
-
-
0036668466
-
Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system
-
Kobayashi M., Itoh K., Suzuki T., Osanai H., Nishikawa K., Katoh Y., et al. Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system. Genes Cells 7 (2002) 807-820
-
(2002)
Genes Cells
, vol.7
, pp. 807-820
-
-
Kobayashi, M.1
Itoh, K.2
Suzuki, T.3
Osanai, H.4
Nishikawa, K.5
Katoh, Y.6
-
97
-
-
3543008924
-
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
-
Kobayashi A., Kang M.I., Okawa H., Ohtsuji M., Zenke Y., Chiba T., et al. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol Cell Biol 24 (2004) 7130-7139
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7130-7139
-
-
Kobayashi, A.1
Kang, M.I.2
Okawa, H.3
Ohtsuji, M.4
Zenke, Y.5
Chiba, T.6
-
98
-
-
3042794972
-
Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes
-
Kobayashi A., Ohta T., and Yamamoto M. Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes. Methods Enzymol 378 (2004) 273-286
-
(2004)
Methods Enzymol
, vol.378
, pp. 273-286
-
-
Kobayashi, A.1
Ohta, T.2
Yamamoto, M.3
-
99
-
-
0029867054
-
Complexity of the erythroid transcription factor NF-E2 as revealed by gene targeting of the mouse p18 NF-E2 locus
-
Kotkow K.J., and Orkin S.H. Complexity of the erythroid transcription factor NF-E2 as revealed by gene targeting of the mouse p18 NF-E2 locus. Proc Natl Acad Sci USA 93 (1996) 3514-3518
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3514-3518
-
-
Kotkow, K.J.1
Orkin, S.H.2
-
100
-
-
0037434737
-
Nrf2 is an inhibitor of the Fas pathway as identified by Achilles' Heel Method, a new function-based approach to gene identification in human cells
-
Kotlo K.U., Yehiely F., Efimova E., Harasty H., Hesabi B., Shchors K., et al. Nrf2 is an inhibitor of the Fas pathway as identified by Achilles' Heel Method, a new function-based approach to gene identification in human cells. Oncogene 22 (2003) 797-806
-
(2003)
Oncogene
, vol.22
, pp. 797-806
-
-
Kotlo, K.U.1
Yehiely, F.2
Efimova, E.3
Harasty, H.4
Hesabi, B.5
Shchors, K.6
-
101
-
-
0842304134
-
Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult
-
Kraft A.D., Johnson D.A., and Johnson J.A. Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult. J Neurosci 24 (2004) 1101-1112
-
(2004)
J Neurosci
, vol.24
, pp. 1101-1112
-
-
Kraft, A.D.1
Johnson, D.A.2
Johnson, J.A.3
-
102
-
-
0031914328
-
Ablation of Nrf2 function does not increase the erythroid or megakaryocytic cell lineage dysfunction caused by p45 NF-E2 gene disruption
-
Kuroha T., Takahashi S., Komeno T., Itoh K., Nagasawa T., and Yamamoto M. Ablation of Nrf2 function does not increase the erythroid or megakaryocytic cell lineage dysfunction caused by p45 NF-E2 gene disruption. J Biochem 123 (1998) 376-379
-
(1998)
J Biochem
, vol.123
, pp. 376-379
-
-
Kuroha, T.1
Takahashi, S.2
Komeno, T.3
Itoh, K.4
Nagasawa, T.5
Yamamoto, M.6
-
103
-
-
0036213691
-
Solution structure of the DNA-binding domain of MafG
-
Kusunoki H., Motohashi H., Katsuoka F., Morohashi A., Yamamoto M., and Tanaka T. Solution structure of the DNA-binding domain of MafG. Nat Struct Biol 9 (2002) 252-256
-
(2002)
Nat Struct Biol
, vol.9
, pp. 252-256
-
-
Kusunoki, H.1
Motohashi, H.2
Katsuoka, F.3
Morohashi, A.4
Yamamoto, M.5
Tanaka, T.6
-
104
-
-
0035260034
-
Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3thione
-
Kwak M.K., Itoh K., Yamamoto M., Sutter T.R., and Kensler T.W. Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3thione. Mol Med 7 (2001) 135-145
-
(2001)
Mol Med
, vol.7
, pp. 135-145
-
-
Kwak, M.K.1
Itoh, K.2
Yamamoto, M.3
Sutter, T.R.4
Kensler, T.W.5
-
105
-
-
0036240610
-
Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter
-
Kwak M.K., Itoh K., Yamamoto M., and Kensler T.W. Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter. Mol Cell Biol 22 (2002) 2883-2892
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2883-2892
-
-
Kwak, M.K.1
Itoh, K.2
Yamamoto, M.3
Kensler, T.W.4
-
106
-
-
0242721624
-
Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway
-
Kwak M.K., Wakabayashi N., Greenlaw J.L., Yamamoto M., and Kensler T.W. Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway. Mol Cell Biol 23 (2003) 8786-8794
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8786-8794
-
-
Kwak, M.K.1
Wakabayashi, N.2
Greenlaw, J.L.3
Yamamoto, M.4
Kensler, T.W.5
-
107
-
-
0037424262
-
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival
-
Kwak M.K., Wakabayashi N., Itoh K., Motohashi H., Yamamoto M., and Kensler T.W. Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival. J Biol Chem 278 (2003) 8135-8145
-
(2003)
J Biol Chem
, vol.278
, pp. 8135-8145
-
-
Kwak, M.K.1
Wakabayashi, N.2
Itoh, K.3
Motohashi, H.4
Yamamoto, M.5
Kensler, T.W.6
-
108
-
-
0039726828
-
L and gss expression in mouse fibroblasts
-
L and gss expression in mouse fibroblasts. J Biol Chem 274 (1999) 37491-37498
-
(1999)
J Biol Chem
, vol.274
, pp. 37491-37498
-
-
Kwong, M.1
Kan, Y.W.2
Chan, J.Y.3
-
109
-
-
0038146898
-
Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis
-
Lee J.M., Calkins M.J., Chan K., Kan Y.W., and Johnson J.A. Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis. J Biol Chem 278 (2003) 12029-12038
-
(2003)
J Biol Chem
, vol.278
, pp. 12029-12038
-
-
Lee, J.M.1
Calkins, M.J.2
Chan, K.3
Kan, Y.W.4
Johnson, J.A.5
-
110
-
-
0141621061
-
NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons
-
Lee J.M., Shih A.Y., Murphy T.H., and Johnson J.A. NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons. J Biol Chem 278 (2003) 37948-37956
-
(2003)
J Biol Chem
, vol.278
, pp. 37948-37956
-
-
Lee, J.M.1
Shih, A.Y.2
Murphy, T.H.3
Johnson, J.A.4
-
111
-
-
3042716482
-
Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia
-
Lee J.M., Chan K., Kan Y.W., and Johnson J.A. Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia. Proc Natl Acad Sci USA 101 (2004) 9751-9756
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9751-9756
-
-
Lee, J.M.1
Chan, K.2
Kan, Y.W.3
Johnson, J.A.4
-
112
-
-
0347481377
-
Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress
-
Leung L., Kwong M., Hou S., Lee C., and Chan J.Y. Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress. J Biol Chem 278 (2003) 48021-48029
-
(2003)
J Biol Chem
, vol.278
, pp. 48021-48029
-
-
Leung, L.1
Kwong, M.2
Hou, S.3
Lee, C.4
Chan, J.Y.5
-
113
-
-
1642282736
-
Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products
-
Levonen A.L., Landar A., Ramachandran A., Ceaser E.K., Dickinson D.A., Zanoni G., et al. Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products. Biochem J 378 (2004) 373-382
-
(2004)
Biochem J
, vol.378
, pp. 373-382
-
-
Levonen, A.L.1
Landar, A.2
Ramachandran, A.3
Ceaser, E.K.4
Dickinson, D.A.5
Zanoni, G.6
-
114
-
-
0026755187
-
Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element
-
Li Y., and Jaiswal A.K. Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element. J Biol Chem 267 (1992) 15097-15104
-
(1992)
J Biol Chem
, vol.267
, pp. 15097-15104
-
-
Li, Y.1
Jaiswal, A.K.2
-
115
-
-
0037016759
-
Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells
-
Li J., Lee J.M., and Johnson J.A. Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells. J Biol Chem 277 (2002) 388-394
-
(2002)
J Biol Chem
, vol.277
, pp. 388-394
-
-
Li, J.1
Lee, J.M.2
Johnson, J.A.3
-
116
-
-
3543084994
-
Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C δ
-
Li B., Wang X., Rasheed N., Hu Y., Boast S., Ishii T., et al. Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C δ. Genes Dev 18 (2004) 1824-1837
-
(2004)
Genes Dev
, vol.18
, pp. 1824-1837
-
-
Li, B.1
Wang, X.2
Rasheed, N.3
Hu, Y.4
Boast, S.5
Ishii, T.6
-
117
-
-
4844225631
-
Genetic dissection of systemic autoimmune disease in Nrf2-deficient mice
-
Li J., Stein T.D., and Johnson J.A. Genetic dissection of systemic autoimmune disease in Nrf2-deficient mice. Physiol Genomics 18 (2004) 261-272
-
(2004)
Physiol Genomics
, vol.18
, pp. 261-272
-
-
Li, J.1
Stein, T.D.2
Johnson, J.A.3
-
118
-
-
11144244006
-
Crystal structure of the Kelch domain of human Keap1
-
Li X., Zhang D., Hannink M., and Beamer L.J. Crystal structure of the Kelch domain of human Keap1. J Biol Chem 279 (2004) 54750-54758
-
(2004)
J Biol Chem
, vol.279
, pp. 54750-54758
-
-
Li, X.1
Zhang, D.2
Hannink, M.3
Beamer, L.J.4
-
119
-
-
23344452360
-
Nrf2 Possesses a redox-insensitive nuclear export signal overlapping with the leucine zipper motif
-
Li W., Jain M.R., Chen C., Yue X., Hebbar V., Zhou R., et al. Nrf2 Possesses a redox-insensitive nuclear export signal overlapping with the leucine zipper motif. J Biol Chem 280 (2005) 28430-28438
-
(2005)
J Biol Chem
, vol.280
, pp. 28430-28438
-
-
Li, W.1
Jain, M.R.2
Chen, C.3
Yue, X.4
Hebbar, V.5
Zhou, R.6
-
120
-
-
0030974478
-
hMAF, a small human transcription factor that heterodimerizes specifically with Nrf1 and Nrf2
-
Marini M.G., Chan K., Casula L., Kan Y.W., Cao A., and Moi P. hMAF, a small human transcription factor that heterodimerizes specifically with Nrf1 and Nrf2. J Biol Chem 272 (1997) 16490-16497
-
(1997)
J Biol Chem
, vol.272
, pp. 16490-16497
-
-
Marini, M.G.1
Chan, K.2
Casula, L.3
Kan, Y.W.4
Cao, A.5
Moi, P.6
-
121
-
-
0032080193
-
Erythroid maturation and globin gene expression in mice with combined deficiency of NF-E2 and Nrf-2
-
Martin F., van Deursen J.M., Shivdasani R.A., Jackson C.W., Troutman A.G., and Ney P.A. Erythroid maturation and globin gene expression in mice with combined deficiency of NF-E2 and Nrf-2. Blood 91 (1998) 3459-3466
-
(1998)
Blood
, vol.91
, pp. 3459-3466
-
-
Martin, F.1
van Deursen, J.M.2
Shivdasani, R.A.3
Jackson, C.W.4
Troutman, A.G.5
Ney, P.A.6
-
122
-
-
1542335553
-
Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol
-
Martin D., Rojo A.I., Salinas M., Diaz R., Gallardo G., Alam J., et al. Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol. J Biol Chem 279 (2004) 8919-8929
-
(2004)
J Biol Chem
, vol.279
, pp. 8919-8929
-
-
Martin, D.1
Rojo, A.I.2
Salinas, M.3
Diaz, R.4
Gallardo, G.5
Alam, J.6
-
123
-
-
0035870298
-
The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes
-
McMahon M., Itoh K., Yamamoto M., Chanas S.A., Henderson C.J., McLellan L.I., et al. The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes. Cancer Res 61 (2001) 3299-3307
-
(2001)
Cancer Res
, vol.61
, pp. 3299-3307
-
-
McMahon, M.1
Itoh, K.2
Yamamoto, M.3
Chanas, S.A.4
Henderson, C.J.5
McLellan, L.I.6
-
124
-
-
0037821802
-
Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
-
McMahon M., Itoh K., Yamamoto M., and Hayes J.D. Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression. J Biol Chem 278 (2003) 21592-21600
-
(2003)
J Biol Chem
, vol.278
, pp. 21592-21600
-
-
McMahon, M.1
Itoh, K.2
Yamamoto, M.3
Hayes, J.D.4
-
125
-
-
3843104763
-
Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron
-
McMahon M., Thomas N., Itoh K., Yamamoto M., and Hayes J.D. Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron. J Biol Chem 279 (2004) 31556-31567
-
(2004)
J Biol Chem
, vol.279
, pp. 31556-31567
-
-
McMahon, M.1
Thomas, N.2
Itoh, K.3
Yamamoto, M.4
Hayes, J.D.5
-
126
-
-
0024534370
-
Two tissue-specific factors bind the erythroid promoter of the human porphobilinogen deaminase gene
-
Mignotte V., Wall L., deBoer E., Grosveld F., and Romeo P.H. Two tissue-specific factors bind the erythroid promoter of the human porphobilinogen deaminase gene. Nucleic Acids Res 17 (1989) 37-54
-
(1989)
Nucleic Acids Res
, vol.17
, pp. 37-54
-
-
Mignotte, V.1
Wall, L.2
deBoer, E.3
Grosveld, F.4
Romeo, P.H.5
-
127
-
-
0037450429
-
Functional role of AhR in the expression of toxic effects by TCDD
-
Mimura J., and Fujii-Kuriyama Y. Functional role of AhR in the expression of toxic effects by TCDD. Biochim Biophys Acta 1619 (2003) 263-268
-
(2003)
Biochim Biophys Acta
, vol.1619
, pp. 263-268
-
-
Mimura, J.1
Fujii-Kuriyama, Y.2
-
128
-
-
0025868833
-
Segmentally restricted, cephalic expression of a leucine zipper gene during Drosophila embryogenesis
-
Mohler J., Vani K., Leung S., and Epstein A. Segmentally restricted, cephalic expression of a leucine zipper gene during Drosophila embryogenesis. Mech Dev 34 (1991) 3-9
-
(1991)
Mech Dev
, vol.34
, pp. 3-9
-
-
Mohler, J.1
Vani, K.2
Leung, S.3
Epstein, A.4
-
129
-
-
0028061444
-
Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the β-globin locus control region
-
Moi P., Chan K., Asunis I., Cao A., and Kan Y.W. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the β-globin locus control region. Proc Natl Acad Sci USA 91 (1994) 9926-9930
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9926-9930
-
-
Moi, P.1
Chan, K.2
Asunis, I.3
Cao, A.4
Kan, Y.W.5
-
130
-
-
0037081778
-
Differential induction of mafF, mafG and mafK expression by electrophile-response-element activators
-
Moran J.A., Dahl E.L., and Mulcahy R.T. Differential induction of mafF, mafG and mafK expression by electrophile-response-element activators. Biochem J 361 (2002) 371-377
-
(2002)
Biochem J
, vol.361
, pp. 371-377
-
-
Moran, J.A.1
Dahl, E.L.2
Mulcahy, R.T.3
-
131
-
-
0036479330
-
A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway
-
Morimitsu Y., Nakagawa Y., Hayashi K., Fujii H., Kumagai T., Nakamura Y., et al. A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway. J Biol Chem 277 (2002) 3456-3463
-
(2002)
J Biol Chem
, vol.277
, pp. 3456-3463
-
-
Morimitsu, Y.1
Nakagawa, Y.2
Hayashi, K.3
Fujii, H.4
Kumagai, T.5
Nakamura, Y.6
-
132
-
-
1642540092
-
Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels
-
Morito N., Yoh K., Itoh K., Hirayama A., Koyama A., Yamamoto M., et al. Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels. Oncogene 22 (2003) 9275-9281
-
(2003)
Oncogene
, vol.22
, pp. 9275-9281
-
-
Morito, N.1
Yoh, K.2
Itoh, K.3
Hirayama, A.4
Koyama, A.5
Yamamoto, M.6
-
133
-
-
0033637756
-
Positive or negative MARE-dependent transcriptional regulation is determined by the abundance of small Maf proteins
-
Motohashi H., Katsuoka F., Shavit J.A., Engel J.D., and Yamamoto M. Positive or negative MARE-dependent transcriptional regulation is determined by the abundance of small Maf proteins. Cell 103 (2000) 865-875
-
(2000)
Cell
, vol.103
, pp. 865-875
-
-
Motohashi, H.1
Katsuoka, F.2
Shavit, J.A.3
Engel, J.D.4
Yamamoto, M.5
-
134
-
-
2342511435
-
Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway
-
Motohashi H., Katsuoka F., Engel J.D., and Yamamoto M. Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway. Proc Natl Acad Sci USA 101 (2004) 6379-6384
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6379-6384
-
-
Motohashi, H.1
Katsuoka, F.2
Engel, J.D.3
Yamamoto, M.4
-
135
-
-
0030072562
-
Mesodermal- vs
-
Motohashi H., Igarashi K., Onodera K., Takahashi S., Ohtani H., Nakafuku M., et al. Mesodermal- vs. neuronal-specific expression of MafK is elicited by different promoters. Genes Cells 1 (1996) 223-238
-
(1996)
neuronal-specific expression of MafK is elicited by different promoters. Genes Cells
, vol.1
, pp. 223-238
-
-
Motohashi, H.1
Igarashi, K.2
Onodera, K.3
Takahashi, S.4
Ohtani, H.5
Nakafuku, M.6
-
136
-
-
0028914295
-
Identification of a putative antioxidant response element in the 5′-flanking region of the human γ-glutamylcysteine synthetase heavy subunit gene
-
Mulcahy R.T., and Gipp J.J. Identification of a putative antioxidant response element in the 5′-flanking region of the human γ-glutamylcysteine synthetase heavy subunit gene. Biochem Biophys Res Commun 209 (1995) 227-233
-
(1995)
Biochem Biophys Res Commun
, vol.209
, pp. 227-233
-
-
Mulcahy, R.T.1
Gipp, J.J.2
-
137
-
-
0032189224
-
Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3′ enhancer
-
Muto A., Hoshino H., Madisen L., Yanai N., Obinata M., Karasuyama H., et al. Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3′ enhancer. EMBO J 17 (1998) 5734-5743
-
(1998)
EMBO J
, vol.17
, pp. 5734-5743
-
-
Muto, A.1
Hoshino, H.2
Madisen, L.3
Yanai, N.4
Obinata, M.5
Karasuyama, H.6
-
138
-
-
0037036377
-
Activation of Maf/AP-1 repressor Bach2 by oxidative stress promotes apoptosis and its interaction with promyelocytic leukemia nuclear bodies
-
Muto A., Tashiro S., Tsuchiya H., Kume A., Kanno M., Ito E., et al. Activation of Maf/AP-1 repressor Bach2 by oxidative stress promotes apoptosis and its interaction with promyelocytic leukemia nuclear bodies. J Biol Chem 277 (2002) 20724-20733
-
(2002)
J Biol Chem
, vol.277
, pp. 20724-20733
-
-
Muto, A.1
Tashiro, S.2
Tsuchiya, H.3
Kume, A.4
Kanno, M.5
Ito, E.6
-
139
-
-
2942537762
-
The transcriptional programme of antibody class switching involves the repressor Bach2
-
Muto A., Tashiro S., Nakajima O., Hoshino H., Takahashi S., Sakoda E., et al. The transcriptional programme of antibody class switching involves the repressor Bach2. Nature 429 (2004) 566-571
-
(2004)
Nature
, vol.429
, pp. 566-571
-
-
Muto, A.1
Tashiro, S.2
Nakajima, O.3
Hoshino, H.4
Takahashi, S.5
Sakoda, E.6
-
140
-
-
0038537298
-
PI3 K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells
-
Nakaso K., Yano H., Fukuhara Y., Takeshima T., Wada-Isoe K., and Nakashima K. PI3 K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells. FEBS Lett 546 (2003) 181-184
-
(2003)
FEBS Lett
, vol.546
, pp. 181-184
-
-
Nakaso, K.1
Yano, H.2
Fukuhara, Y.3
Takeshima, T.4
Wada-Isoe, K.5
Nakashima, K.6
-
141
-
-
0025080566
-
Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein
-
Ney P.A., Sorrentino B.P., Lowrey C.H., and Nienhuis A.W. Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein. Nucleic Acids Res 18 (1990) 6011-6017
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 6011-6017
-
-
Ney, P.A.1
Sorrentino, B.P.2
Lowrey, C.H.3
Nienhuis, A.W.4
-
142
-
-
0027295567
-
Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner
-
Ney P.A., Andrews N.C., Jane S.M., Safer B., Purucker M.E., Weremowicz S., et al. Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner. Mol Cell Biol 13 (1993) 5604-5612
-
(1993)
Mol Cell Biol
, vol.13
, pp. 5604-5612
-
-
Ney, P.A.1
Andrews, N.C.2
Jane, S.M.3
Safer, B.4
Purucker, M.E.5
Weremowicz, S.6
-
143
-
-
0034685897
-
Transcriptional regulation of the antioxidant response element. Activation by Nrf2 and repression by MafK
-
Nguyen T., Huang H.C., and Pickett C.B. Transcriptional regulation of the antioxidant response element. Activation by Nrf2 and repression by MafK. J Biol Chem 275 (2000) 15466-15473
-
(2000)
J Biol Chem
, vol.275
, pp. 15466-15473
-
-
Nguyen, T.1
Huang, H.C.2
Pickett, C.B.3
-
144
-
-
0013282861
-
Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome
-
Nguyen T., Sherratt P.J., Huang H.C., Yang C.S., and Pickett C.B. Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome. J Biol Chem 278 (2003) 4536-4541
-
(2003)
J Biol Chem
, vol.278
, pp. 4536-4541
-
-
Nguyen, T.1
Sherratt, P.J.2
Huang, H.C.3
Yang, C.S.4
Pickett, C.B.5
-
145
-
-
25444449520
-
Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1
-
Nguyen T., Sherratt P.J., Nioi P., Yang C.S., and Pickett C.B. Nrf2 controls constitutive and inducible expression of ARE-driven genes through a dynamic pathway involving nucleocytoplasmic shuttling by Keap1. J Biol Chem 280 (2005) 32485-32492
-
(2005)
J Biol Chem
, vol.280
, pp. 32485-32492
-
-
Nguyen, T.1
Sherratt, P.J.2
Nioi, P.3
Yang, C.S.4
Pickett, C.B.5
-
146
-
-
14644397287
-
Transcription factor Nrf2 regulates promoter activity of mouse aldose reductase (AKR1B3) gene
-
Nishinaka T., and Yabe-Nishimura C. Transcription factor Nrf2 regulates promoter activity of mouse aldose reductase (AKR1B3) gene. J Pharmacol Sci 97 (2005) 43-51
-
(2005)
J Pharmacol Sci
, vol.97
, pp. 43-51
-
-
Nishinaka, T.1
Yabe-Nishimura, C.2
-
147
-
-
0041742490
-
Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress
-
Numazawa S., Ishikawa M., Yoshida A., Tanaka S., and Yoshida T. Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress. Am J Physiol Cell Physiol 285 (2003) C334-C342
-
(2003)
Am J Physiol Cell Physiol
, vol.285
-
-
Numazawa, S.1
Ishikawa, M.2
Yoshida, A.3
Tanaka, S.4
Yoshida, T.5
-
148
-
-
0024463596
-
Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in the rat glutathione transferase P gene
-
Okuda A., Imagawa M., Maeda Y., Sakai M., and Muramatsu M. Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in the rat glutathione transferase P gene. J Biol Chem 264 (1989) 16919-16926
-
(1989)
J Biol Chem
, vol.264
, pp. 16919-16926
-
-
Okuda, A.1
Imagawa, M.2
Maeda, Y.3
Sakai, M.4
Muramatsu, M.5
-
149
-
-
0033597860
-
Characterization of the murine mafF gene
-
Onodera K., Shavit J.A., Motohashi H., Katsuoka F., Akasaka J.E., Engel J.D., et al. Characterization of the murine mafF gene. J Biol Chem 274 (1999) 21162-21169
-
(1999)
J Biol Chem
, vol.274
, pp. 21162-21169
-
-
Onodera, K.1
Shavit, J.A.2
Motohashi, H.3
Katsuoka, F.4
Akasaka, J.E.5
Engel, J.D.6
-
150
-
-
0034653880
-
Perinatal synthetic lethality and hematopoietic defects in compound mafG:mafK mutant mice
-
Onodera K., Shavit J.A., Motohashi H., Yamamoto M., and Engel J.D. Perinatal synthetic lethality and hematopoietic defects in compound mafG:mafK mutant mice. EMBO J 19 (2000) 1335-1345
-
(2000)
EMBO J
, vol.19
, pp. 1335-1345
-
-
Onodera, K.1
Shavit, J.A.2
Motohashi, H.3
Yamamoto, M.4
Engel, J.D.5
-
151
-
-
0029805130
-
Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site
-
Oyake T., Itoh K., Motohashi H., Hayashi N., Hoshino H., Nishizawa M., et al. Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol Cell Biol 16 (1996) 6083-6095
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6083-6095
-
-
Oyake, T.1
Itoh, K.2
Motohashi, H.3
Hayashi, N.4
Hoshino, H.5
Nishizawa, M.6
-
152
-
-
33344456501
-
Structural basis for defects of Keapl activity provoked by its point mutations in lung cancer
-
Padmanabhan B., Tong K.I., Ohta T., Nakamura Y., Scharlock M., Ohtsuji M., et al. Structural basis for defects of Keapl activity provoked by its point mutations in lung cancer. Mol Cell 21 (2006) 689-700
-
(2006)
Mol Cell
, vol.21
, pp. 689-700
-
-
Padmanabhan, B.1
Tong, K.I.2
Ohta, T.3
Nakamura, Y.4
Scharlock, M.5
Ohtsuji, M.6
-
153
-
-
4744360664
-
NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells
-
Papaiahgari S., Kleeberger S.R., Cho H.Y., Kalvakolanu D.V., and Reddy S.P. NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells. J Biol Chem 279 (2004) 42302-42312
-
(2004)
J Biol Chem
, vol.279
, pp. 42302-42312
-
-
Papaiahgari, S.1
Kleeberger, S.R.2
Cho, H.Y.3
Kalvakolanu, D.V.4
Reddy, S.P.5
-
154
-
-
2442658079
-
Transactivation of the PPAR-responsive enhancer module in chemopreventive glutathione S-transferase gene by the peroxisome proliferator-activated receptor-gamma and retinoid X receptor heterodimer
-
Park E.Y., Cho I.J., and Kim S.G. Transactivation of the PPAR-responsive enhancer module in chemopreventive glutathione S-transferase gene by the peroxisome proliferator-activated receptor-gamma and retinoid X receptor heterodimer. Cancer Res 64 (2004) 3701-3713
-
(2004)
Cancer Res
, vol.64
, pp. 3701-3713
-
-
Park, E.Y.1
Cho, I.J.2
Kim, S.G.3
-
155
-
-
0037462675
-
Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones
-
Pietsch E.C., Chan J.Y., Torti F.M., and Torti S.V. Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones. J Biol Chem 278 (2003) 2361-2369
-
(2003)
J Biol Chem
, vol.278
, pp. 2361-2369
-
-
Pietsch, E.C.1
Chan, J.Y.2
Torti, F.M.3
Torti, S.V.4
-
156
-
-
0035283587
-
Redox-operated genetic switches: the SoxR and OxyR transcription factors
-
Pomposiello P.J., and Demple B. Redox-operated genetic switches: the SoxR and OxyR transcription factors. Trends Biotechnol 19 (2001) 109-114
-
(2001)
Trends Biotechnol
, vol.19
, pp. 109-114
-
-
Pomposiello, P.J.1
Demple, B.2
-
157
-
-
2942606074
-
Molecular phylogeny of the kelch-repeat superfamily reveals an expansion of BTB/kelch proteins in animals
-
Prag S., and Adams J.C. Molecular phylogeny of the kelch-repeat superfamily reveals an expansion of BTB/kelch proteins in animals. BMC Bioinformatics 4 (2003) 42
-
(2003)
BMC Bioinformatics
, vol.4
, pp. 42
-
-
Prag, S.1
Adams, J.C.2
-
158
-
-
0029411321
-
Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE)
-
Prestera T., Talalay P., Alam J., Ahn Y.I., Lee P.J., and Choi A.M. Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE). Mol Med 1 (1995) 827-837
-
(1995)
Mol Med
, vol.1
, pp. 827-837
-
-
Prestera, T.1
Talalay, P.2
Alam, J.3
Ahn, Y.I.4
Lee, P.J.5
Choi, A.M.6
-
160
-
-
0035853157
-
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
-
Ramos-Gomez M., Kwak M.K., Dolan P.M., Itoh K., Yamamoto M., Talalay P., et al. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc Natl Acad Sci USA 98 (2001) 3410-3415
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3410-3415
-
-
Ramos-Gomez, M.1
Kwak, M.K.2
Dolan, P.M.3
Itoh, K.4
Yamamoto, M.5
Talalay, P.6
-
161
-
-
0037356451
-
Interactive effects of nrf2 genotype and oltipraz on benzo[a]pyrene-DNA adducts and tumor yield in mice
-
Ramos-Gomez M., Dolan P.M., Itoh K., Yamamoto M., and Kensler T.W. Interactive effects of nrf2 genotype and oltipraz on benzo[a]pyrene-DNA adducts and tumor yield in mice. Carcinogenesis 24 (2003) 461-467
-
(2003)
Carcinogenesis
, vol.24
, pp. 461-467
-
-
Ramos-Gomez, M.1
Dolan, P.M.2
Itoh, K.3
Yamamoto, M.4
Kensler, T.W.5
-
162
-
-
15244356847
-
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
-
Rangasamy T., Cho C.Y., Thimmulappa R.K., Zhen L., Srisuma S.S., Kensler T.W., et al. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest 114 (2004) 1248-1259
-
(2004)
J Clin Invest
, vol.114
, pp. 1248-1259
-
-
Rangasamy, T.1
Cho, C.Y.2
Thimmulappa, R.K.3
Zhen, L.4
Srisuma, S.S.5
Kensler, T.W.6
-
163
-
-
22344438250
-
Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice
-
Rangasamy T., Guo J., Mitzner W.A., Roman J., Singh A., Fryer A.D., et al. Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice. J Exp Med 202 (2005) 47-59
-
(2005)
J Exp Med
, vol.202
, pp. 47-59
-
-
Rangasamy, T.1
Guo, J.2
Mitzner, W.A.3
Roman, J.4
Singh, A.5
Fryer, A.D.6
-
164
-
-
0027231631
-
The structure of two murine class-mu glutathione transferase genes coordinately induced by butylated hydroxyanisole
-
Reinhart J., and Pearson W.R. The structure of two murine class-mu glutathione transferase genes coordinately induced by butylated hydroxyanisole. Arch Biochem Biophys 303 (1993) 383-393
-
(1993)
Arch Biochem Biophys
, vol.303
, pp. 383-393
-
-
Reinhart, J.1
Pearson, W.R.2
-
165
-
-
0006349025
-
Mutational analysis of the chicken β-globin enhancer reveals two positive-acting domains
-
Reitman M., and Felsenfeld G. Mutational analysis of the chicken β-globin enhancer reveals two positive-acting domains. Proc Natl Acad Sci USA 85 (1988) 6267-6271
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 6267-6271
-
-
Reitman, M.1
Felsenfeld, G.2
-
166
-
-
0024997241
-
Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants
-
Rushmore T.H., and Pickett C.B. Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants. J Biol Chem 265 (1990) 14648-14653
-
(1990)
J Biol Chem
, vol.265
, pp. 14648-14653
-
-
Rushmore, T.H.1
Pickett, C.B.2
-
167
-
-
0025368036
-
Regulation of glutathione S-transferase Ya subunit gene expression: identification of a unique xenobiotic-responsive element controlling inducible expression by planar aromatic compounds
-
Rushmore T.H., King R.G., Paulson K.E., and Pickett C.B. Regulation of glutathione S-transferase Ya subunit gene expression: identification of a unique xenobiotic-responsive element controlling inducible expression by planar aromatic compounds. Proc Natl Acad Sci USA 87 (1990) 3826-3830
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 3826-3830
-
-
Rushmore, T.H.1
King, R.G.2
Paulson, K.E.3
Pickett, C.B.4
-
168
-
-
0025948113
-
The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
-
Rushmore T.H., Morton M.R., and Pickett C.B. The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J Biol Chem 266 (1991) 11632-11639
-
(1991)
J Biol Chem
, vol.266
, pp. 11632-11639
-
-
Rushmore, T.H.1
Morton, M.R.2
Pickett, C.B.3
-
169
-
-
10944235410
-
Nrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene
-
Sankaranarayanan K., and Jaiswal A.K. Nrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene. J Biol Chem 279 (2004) 50810-50817
-
(2004)
J Biol Chem
, vol.279
, pp. 50810-50817
-
-
Sankaranarayanan, K.1
Jaiswal, A.K.2
-
170
-
-
0037160092
-
Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression
-
Sasaki H., Sato H., Kuriyama-Matsumura K., Sato K., Maebara K., Wang H., et al. Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression. J Biol Chem 277 (2002) 44765-44771
-
(2002)
J Biol Chem
, vol.277
, pp. 44765-44771
-
-
Sasaki, H.1
Sato, H.2
Kuriyama-Matsumura, K.3
Sato, K.4
Maebara, K.5
Wang, H.6
-
171
-
-
18344387893
-
Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of γ-glutamylcysteine synthetase
-
Sekhar K.R., Spitz D.R., Harris S., Nguyen T.T., Meredith M.J., Holt J.T., et al. Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of γ-glutamylcysteine synthetase. Free Radic Biol Med 32 (2002) 650-662
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 650-662
-
-
Sekhar, K.R.1
Spitz, D.R.2
Harris, S.3
Nguyen, T.T.4
Meredith, M.J.5
Holt, J.T.6
-
172
-
-
0037015682
-
Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2
-
Sekhar K.R., Yan X.X., and Freeman M.L. Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2. Oncogene 21 (2002) 6829-6834
-
(2002)
Oncogene
, vol.21
, pp. 6829-6834
-
-
Sekhar, K.R.1
Yan, X.X.2
Freeman, M.L.3
-
173
-
-
0032527757
-
Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice
-
Shavit J.A., Motohashi H., Onodera K., Akasaka J., Yamamoto M., and Engel J.D. Impaired megakaryopoiesis and behavioral defects in mafG-null mutant mice. Genes Dev 12 (1998) 2164-2174
-
(1998)
Genes Dev
, vol.12
, pp. 2164-2174
-
-
Shavit, J.A.1
Motohashi, H.2
Onodera, K.3
Akasaka, J.4
Yamamoto, M.5
Engel, J.D.6
-
174
-
-
2542418930
-
Regulation of Nrf2 transactivation domain activity. The differential effects of mitogen-activated protein kinase cascades and synergistic stimulatory effect of Raf and CREB-binding protein
-
Shen G., Hebbar V., Nair S., Xu C., Li W., Lin W., et al. Regulation of Nrf2 transactivation domain activity. The differential effects of mitogen-activated protein kinase cascades and synergistic stimulatory effect of Raf and CREB-binding protein. J Biol Chem 279 (2004) 23052-23060
-
(2004)
J Biol Chem
, vol.279
, pp. 23052-23060
-
-
Shen, G.1
Hebbar, V.2
Nair, S.3
Xu, C.4
Li, W.5
Lin, W.6
-
175
-
-
20744440945
-
Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo
-
Shih A.Y., Imbeault S., Barakauskas V., Erb H., Jiang L., Li P., et al. Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo. J Biol Chem 280 (2005) 22925-22936
-
(2005)
J Biol Chem
, vol.280
, pp. 22925-22936
-
-
Shih, A.Y.1
Imbeault, S.2
Barakauskas, V.3
Erb, H.4
Jiang, L.5
Li, P.6
-
176
-
-
0029050860
-
Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2
-
Shivdasani R.A., and Orkin S.H. Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2. Proc Natl Acad Sci USA 92 (1995) 8690-8694
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8690-8694
-
-
Shivdasani, R.A.1
Orkin, S.H.2
-
177
-
-
0029051295
-
Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development
-
Shivdasani R.A., Rosenblatt M.F., Zucker-Franklin D., Jackson C.W., Hunt P., Saris C.J.M., et al. Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/MGDF in megakaryocyte development. Cell 81 (1995) 695-704
-
(1995)
Cell
, vol.81
, pp. 695-704
-
-
Shivdasani, R.A.1
Rosenblatt, M.F.2
Zucker-Franklin, D.3
Jackson, C.W.4
Hunt, P.5
Saris, C.J.M.6
-
178
-
-
0036570346
-
Glutamate-cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress
-
Solis W.A., Dalton T.P., Dieter M.Z., Freshwater S., Harrer J.M., He L., et al. Glutamate-cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress. Biochem Pharmacol 63 (2002) 1739-1754
-
(2002)
Biochem Pharmacol
, vol.63
, pp. 1739-1754
-
-
Solis, W.A.1
Dalton, T.P.2
Dieter, M.Z.3
Freshwater, S.4
Harrer, J.M.5
He, L.6
-
179
-
-
0037462651
-
Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium
-
Stewart D., Killeen E., Naquin R., Alam S., and Alam J. Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium. J Biol Chem 278 (2003) 2396-2402
-
(2003)
J Biol Chem
, vol.278
, pp. 2396-2402
-
-
Stewart, D.1
Killeen, E.2
Naquin, R.3
Alam, S.4
Alam, J.5
-
180
-
-
4644293440
-
Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein
-
Strachan G.D., Morgan K.L., Otis L.L., Caltagarone J., Gittis A., Bowser R., et al. Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein. Biochemistry 43 (2004) 12113-12122
-
(2004)
Biochemistry
, vol.43
, pp. 12113-12122
-
-
Strachan, G.D.1
Morgan, K.L.2
Otis, L.L.3
Caltagarone, J.4
Gittis, A.5
Bowser, R.6
-
181
-
-
0026725369
-
In vivo footprinting of the human α-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction
-
Strauss E.C., Andrews N.C., Higgs D.R., and Orkin S.H. In vivo footprinting of the human α-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction. Mol Cell Biol 12 (1992) 2135-2142
-
(1992)
Mol Cell Biol
, vol.12
, pp. 2135-2142
-
-
Strauss, E.C.1
Andrews, N.C.2
Higgs, D.R.3
Orkin, S.H.4
-
182
-
-
1542723493
-
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
-
Suh J.H., Shenvi S.V., Dixon B.M., Liu H., Jaiswal A.K., Liu R.M., et al. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc Natl Acad Sci USA 101 (2004) 3381-3386
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3381-3386
-
-
Suh, J.H.1
Shenvi, S.V.2
Dixon, B.M.3
Liu, H.4
Jaiswal, A.K.5
Liu, R.M.6
-
183
-
-
18644378321
-
Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene
-
Sun J., Hoshino H., Takaku K., Nakajima O., Muto A., Suzuki H., et al. Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene. EMBO J 21 (2002) 5216-5224
-
(2002)
EMBO J
, vol.21
, pp. 5216-5224
-
-
Sun, J.1
Hoshino, H.2
Takaku, K.3
Nakajima, O.4
Muto, A.5
Suzuki, H.6
-
185
-
-
19544372581
-
Pi-class glutathione S-transferase genes are regulated by Nrf2 through an evolutionarily conserved regulatory element in zebrafish
-
Suzuki T., Takagi Y., Osanai H., Li L., Takeuchi M., Katoh Y., et al. Pi-class glutathione S-transferase genes are regulated by Nrf2 through an evolutionarily conserved regulatory element in zebrafish. Biochem J (2005)
-
(2005)
Biochem J
-
-
Suzuki, T.1
Takagi, Y.2
Osanai, H.3
Li, L.4
Takeuchi, M.5
Katoh, Y.6
-
186
-
-
2942689213
-
MafT, a new member of the small Maf protein family in zebrafish
-
Takagi Y., Kobayashi M., Li L., Suzuki T., Nishikawa K., and Yamamoto M. MafT, a new member of the small Maf protein family in zebrafish. Biochem Biophys Res Commun 320 (2004) 62-69
-
(2004)
Biochem Biophys Res Commun
, vol.320
, pp. 62-69
-
-
Takagi, Y.1
Kobayashi, M.2
Li, L.3
Suzuki, T.4
Nishikawa, K.5
Yamamoto, M.6
-
187
-
-
0038378322
-
Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis
-
Talalay P., Dinkova-Kostova A.T., and Holtzclaw W.D. Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis. Adv Enzyme Regul 43 (2003) 121-134
-
(2003)
Adv Enzyme Regul
, vol.43
, pp. 121-134
-
-
Talalay, P.1
Dinkova-Kostova, A.T.2
Holtzclaw, W.D.3
-
188
-
-
0037106099
-
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
-
Thimmulappa R.K., Mai K.H., Srisuma S., Kensler T.W., Yamamoto M., and Biswal S. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res 62 (2002) 5196-5203
-
(2002)
Cancer Res
, vol.62
, pp. 5196-5203
-
-
Thimmulappa, R.K.1
Mai, K.H.2
Srisuma, S.3
Kensler, T.W.4
Yamamoto, M.5
Biswal, S.6
-
189
-
-
8244250764
-
Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif
-
Toki T., Itoh J., Kitazawa J., Arai K., Hatakeyama K., Akasaka J., et al. Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif. Oncogene 14 (1997) 1901-1910
-
(1997)
Oncogene
, vol.14
, pp. 1901-1910
-
-
Toki, T.1
Itoh, J.2
Kitazawa, J.3
Arai, K.4
Hatakeyama, K.5
Akasaka, J.6
-
190
-
-
33344463325
-
Keapl recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model
-
Tong K.I., Katoh Y., Kusunoki H., Itoh K., Tanaka T., and Yamamoto M. Keapl recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model. Mol Cell Biol 26 (2006) 2887-2900
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2887-2900
-
-
Tong, K.I.1
Katoh, Y.2
Kusunoki, H.3
Itoh, K.4
Tanaka, T.5
Yamamoto, M.6
-
191
-
-
21844474290
-
Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival
-
Vargas M.R., Pehar M., Cassina P., Martinez-Palma L., Thompson J.A., Beckman J.S., et al. Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival. J Biol Chem 280 (2005) 25571-25579
-
(2005)
J Biol Chem
, vol.280
, pp. 25571-25579
-
-
Vargas, M.R.1
Pehar, M.2
Cassina, P.3
Martinez-Palma, L.4
Thompson, J.A.5
Beckman, J.S.6
-
192
-
-
18944373186
-
Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism
-
Velichkova M., and Hasson T. Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism. Mol Cell Biol 25 (2005) 4501-4513
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4501-4513
-
-
Velichkova, M.1
Hasson, T.2
-
193
-
-
0029906134
-
Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene
-
Venugopal R., and Jaiswal A.K. Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene. Proc Natl Acad Sci USA 93 (1996) 14960-14965
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14960-14965
-
-
Venugopal, R.1
Jaiswal, A.K.2
-
194
-
-
0032542213
-
Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes
-
Venugopal R., and Jaiswal A.K. Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes. Oncogene 17 (1998) 3145-3156
-
(1998)
Oncogene
, vol.17
, pp. 3145-3156
-
-
Venugopal, R.1
Jaiswal, A.K.2
-
195
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
-
Wakabayashi N., Itoh K., Wakabayashi J., Motohashi H., Noda S., Takahashi S., et al. Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation. Nat Genet 35 (2003) 238-245
-
(2003)
Nat Genet
, vol.35
, pp. 238-245
-
-
Wakabayashi, N.1
Itoh, K.2
Wakabayashi, J.3
Motohashi, H.4
Noda, S.5
Takahashi, S.6
-
196
-
-
1242296811
-
Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers
-
Wakabayashi N., Dinkova-Kostova A.T., Holtzclaw W.D., Kang M.I., Kobayashi A., Yamamoto M., et al. Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers. Proc Natl Acad Sci USA 101 (2004) 2040-2045
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2040-2045
-
-
Wakabayashi, N.1
Dinkova-Kostova, A.T.2
Holtzclaw, W.D.3
Kang, M.I.4
Kobayashi, A.5
Yamamoto, M.6
-
197
-
-
0031000208
-
Functional antioxidant responsive elements
-
Wasserman W.W., and Fahl W.E. Functional antioxidant responsive elements. Proc Natl Acad Sci USA 94 (1997) 5361-5366
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5361-5366
-
-
Wasserman, W.W.1
Fahl, W.E.2
-
198
-
-
0033584867
-
Regulation of γ-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2
-
Wild A.C., Moinova H.R., and Mulcahy R.T. Regulation of γ-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2. J Biol Chem 274 (1999) 33627-33636
-
(1999)
J Biol Chem
, vol.274
, pp. 33627-33636
-
-
Wild, A.C.1
Moinova, H.R.2
Mulcahy, R.T.3
-
199
-
-
0032583548
-
Disruption of c-Fos leads to increased expression of NAD(P)H:quinone oxidoreductase1 and glutathione S-transferase
-
Wilkinson J., Radjendirane V., Pfeiffer G.R., Jaiswal A.K., and Clapper M.L. Disruption of c-Fos leads to increased expression of NAD(P)H:quinone oxidoreductase1 and glutathione S-transferase. Biochem Biophys Res Commun 253 (1998) 855-858
-
(1998)
Biochem Biophys Res Commun
, vol.253
, pp. 855-858
-
-
Wilkinson, J.1
Radjendirane, V.2
Pfeiffer, G.R.3
Jaiswal, A.K.4
Clapper, M.L.5
-
200
-
-
15244359632
-
Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia
-
Xu Z., Chen L., Leung L., Yen T.S.B., Lee C., and Chan J.Y. Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia. Proc Natl Acad Sci USA 102 (2005) 4120-4125
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4120-4125
-
-
Xu, Z.1
Chen, L.2
Leung, L.3
Yen, T.S.B.4
Lee, C.5
Chan, J.Y.6
-
201
-
-
7444251509
-
Identification of polymorphisms in the promoter region of the human NRF2 gene
-
Yamamoto T., Yoh K., Kobayashi A., Ishii Y., Kure S., Koyama A., et al. Identification of polymorphisms in the promoter region of the human NRF2 gene. Biochem Biophys Res Commun 321 (2004) 72-79
-
(2004)
Biochem Biophys Res Commun
, vol.321
, pp. 72-79
-
-
Yamamoto, T.1
Yoh, K.2
Kobayashi, A.3
Ishii, Y.4
Kure, S.5
Koyama, A.6
-
202
-
-
0034785941
-
Nrf2-deficient female mice develop lupus-like autoimmune nephritis
-
Yoh K., Itoh K., Enomoto A., Hirayama A., Yamaguchi N., Kobayashi M., et al. Nrf2-deficient female mice develop lupus-like autoimmune nephritis. Kidney Int 60 (2001) 1343-1353
-
(2001)
Kidney Int
, vol.60
, pp. 1343-1353
-
-
Yoh, K.1
Itoh, K.2
Enomoto, A.3
Hirayama, A.4
Yamaguchi, N.5
Kobayashi, M.6
-
203
-
-
0035213298
-
Transgenic over-expression of MafK suppresses T cell proliferation and function in vivo
-
Yoh K., Sugawara T., Motohashi H., Takahama Y., Koyama A., Yamamoto M., et al. Transgenic over-expression of MafK suppresses T cell proliferation and function in vivo. Genes Cells 6 (2001) 1055-1066
-
(2001)
Genes Cells
, vol.6
, pp. 1055-1066
-
-
Yoh, K.1
Sugawara, T.2
Motohashi, H.3
Takahama, Y.4
Koyama, A.5
Yamamoto, M.6
-
204
-
-
6744219613
-
Long range interaction of cis-DNA elements mediated by architectural transcription factor Bach1
-
Yoshida C., Tokumasu F., Hohmura K.I., Bungert J., Hayashi N., Nagasawa T., et al. Long range interaction of cis-DNA elements mediated by architectural transcription factor Bach1. Genes Cells 4 (1999) 643-655
-
(1999)
Genes Cells
, vol.4
, pp. 643-655
-
-
Yoshida, C.1
Tokumasu, F.2
Hohmura, K.I.3
Bungert, J.4
Hayashi, N.5
Nagasawa, T.6
-
205
-
-
0034704079
-
Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism
-
Yu R., Chen C., Mo Y.Y., Hebbar V., Owuor E.D., Tan T.H., et al. Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism. J Biol Chem 275 (2000) 39907-39913
-
(2000)
J Biol Chem
, vol.275
, pp. 39907-39913
-
-
Yu, R.1
Chen, C.2
Mo, Y.Y.3
Hebbar, V.4
Owuor, E.D.5
Tan, T.H.6
-
206
-
-
0242580049
-
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
-
Zhang D.D., and Hannink M. Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress. Mol Cell Biol 23 (2003) 8137-8151
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8137-8151
-
-
Zhang, D.D.1
Hannink, M.2
-
207
-
-
10044228504
-
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
-
Zhang D.D., Lo S.C., Cross J.V., Templeton D.J., and Hannink M. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Mol Cell Biol 24 (2004) 10941-10953
-
(2004)
Mol Cell Biol
, vol.24
, pp. 10941-10953
-
-
Zhang, D.D.1
Lo, S.C.2
Cross, J.V.3
Templeton, D.J.4
Hannink, M.5
-
209
-
-
24044466764
-
Ubiquitination of keap1, a BTB-kelch substrate adaptor protein for Cul3, targets keap1 for degradation by a proteasome-independent pathway
-
Zhang D.D., Lo S.C., Sun Z., Habib G.M., Lieberman M.W., and Hannink M. Ubiquitination of keap1, a BTB-kelch substrate adaptor protein for Cul3, targets keap1 for degradation by a proteasome-independent pathway. J Biol Chem 280 (2005) 30091-30099
-
(2005)
J Biol Chem
, vol.280
, pp. 30091-30099
-
-
Zhang, D.D.1
Lo, S.C.2
Sun, Z.3
Habib, G.M.4
Lieberman, M.W.5
Hannink, M.6
-
210
-
-
0034687543
-
Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes
-
Zipper L.M., and Mulcahy R.T. Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes. Biochem Biophys Res Commun 278 (2000) 484-492
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 484-492
-
-
Zipper, L.M.1
Mulcahy, R.T.2
-
211
-
-
0037183998
-
The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm
-
Zipper L.M., and Mulcahy R.T. The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm. J Biol Chem 277 (2002) 36544-36552
-
(2002)
J Biol Chem
, vol.277
, pp. 36544-36552
-
-
Zipper, L.M.1
Mulcahy, R.T.2
-
212
-
-
0038663090
-
Erk activation is required for Nrf2 nuclear localization during pyrrolidine dithiocarbamate induction of glutamate cysteine ligase modulatory gene expression in HepG2 cells
-
Zipper L.M., and Mulcahy R.T. Erk activation is required for Nrf2 nuclear localization during pyrrolidine dithiocarbamate induction of glutamate cysteine ligase modulatory gene expression in HepG2 cells. Toxicol Sci 73 (2003) 124-134
-
(2003)
Toxicol Sci
, vol.73
, pp. 124-134
-
-
Zipper, L.M.1
Mulcahy, R.T.2
|