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Volumn 277, Issue 5, 2002, Pages 3456-3463

A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway

(12) Morimitsu, Yasujiro a Nakagawa, Yoko a Hayashi, Kazuhiro a Fujii, Hiroyuki b Kumagai, Takeshi b Nakamura, Yoshimasa a,b Osawa, Toshihiko a Horio, Fumihiko a Itoh, Ken a Iida, Katsuyuki a,b Yamamoto, Masayuki a,b Uchida, Koji a,b

a NAGOYA UNIVERSITY (Japan)

b UNIVERSITY OF TSUKUBA (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; BIOLOGICAL ORGANS; CELL CULTURE; DETOXIFICATION; ENZYMES; GENES;

NUCLEAR LOCALIZATION;

BIOCHEMISTRY;

ANTIOXIDANT; GLUTATHIONE TRANSFERASE; ISOTHIOCYANIC ACID DERIVATIVE; PHENOL DERIVATIVE; PLANT EXTRACT; SULFORAPHANE; SULFORAPHANE DERIVATIVE; UNCLASSIFIED DRUG; WASABIA JAPONICA EXTRACT;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BROCCOLI; CANCER RESISTANCE; CONTROLLED STUDY; DETOXIFICATION; DNA RESPONSIVE ELEMENT; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; ENZYME INDUCTION; ISOLATION PROCEDURE; NONHUMAN; PLANT; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; TRANSCRIPTION REGULATION; WASABI;

ANIMALS; ANTICARCINOGENIC AGENTS; CARCINOGENS; CLONING, MOLECULAR; DNA-BINDING PROTEINS; ENZYME INDUCTION; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE TRANSFERASE; JAPAN; KINETICS; LEUCINE ZIPPERS; METABOLIC DETOXICATION, DRUG; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; PLANT EXTRACTS; PLANT ROOTS; RECOMBINANT PROTEINS; THIOCYANATES; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED;

ANIMALIA; ARMORACIA RUSTICANA; BRASSICA OLERACEA VAR. BOTRYTIS; EUTREMA; EUTREMA WASABI; JAPONICA;

EID: 0036479330 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M110244200 Document Type: Article

Times cited : (243)

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