The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm

Journal of Biological Chemistry

Volumn 277, Issue 39, 2002, Pages 36544-36552

  Zipper, Laurie M ^a,b   Timothy Mulcahy, R ^a  

^a UNIVERSITY OF WISCONSIN   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; DETOXIFICATION; DIMERIZATION; ENZYMES;

TRANSCRIPTION FACTORS;

BIOCHEMISTRY;

ACTIN BINDING PROTEIN; PROTEIN; PROTEIN KEAP1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DIMERIZATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN TRANSPORT; TRANSACTIVATION; TRANSCRIPTION REGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL LINE; CELL NUCLEUS; CYTOPLASM; CYTOSKELETAL PROTEINS; DIMERIZATION; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; LUCIFERASES; LUMINESCENT PROTEINS; MICE; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NF-E2-RELATED FACTOR 2; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PRECIPITIN TESTS; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

PROKARYOTA;

EID: 0037183998     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206530200     Document Type: Article

References (56)

1. Favreau, L. V., and Pickett, C. B. (1995) J. Biol. Chem. 270, 24468-24474
2. Mulcahy, R. T., Wartman, M. A., Bailey, H. H., and Gipp, J. J. (1997) J. Biol. Chem. 272, 7445-7454
3. Nguyen, T., Rushmore, T. H., and Pickett, C. B. (1994) J. Biol. Chem. 269, 13656-13662
4. Wild, A. C., Gipp, J. J., and Mulcahy, T. (1998) Biochem. J. 332, 373-381
5. Talalay, P., Fahey, J. W., Holtzclaw, W. D., Prestera, T., and Zhang, Y. (1995) Toxicol. Lett. (Shannon) 82-83, 173-179
6. Igarashi, K., Kataoka, K., Itoh, K., Hayashi, N., Nishizawa, M., and Yamamoto, M. (1994) Nature 367, 568-572
7. Kotkow, K. J., and Orkin, S. H. (1995) Mol. Cell. Biol. 15, 4640-4647
8. Alam, J., Stewart, D., Touchard, C., Boinapally, S., Choi, A. M., and Cook, J. L. (1999) J. Biol. Chem. 274, 26071-26078
9. Alam, J., Wicks, C., Stewart, D., Gong, P., Touchard, C., Otterbein, S., Choi, A. M., Burow, M. E., and Tou, J. (2000) J. Biol. Chem. 275, 27694-27702
10. Itoh, K., Chiba, T., Takahashi, S., Ishii, T., Igarashi, K., Katoh, Y., Oyake, T., Hayashi, N., Satoh, K., Hatayama, I., Yamamoto, M., and Nabeshima, Y. (1997) Biochem. Biophys. Res. Commun. 236, 313-322
11. Jeyapaul, J., and Jaiswal, A. K. (2000) Biochem. Pharmacol. 59, 1433-1439
12. Kim, Y. C., Masutani, H., Yamaguchi, Y., Itoh, K., Yamamoto, M., and Yodoi, J. (2001) J. Biol. Chem. 276, 18399-18406
13. Lee, J. M., Moehlenkamp, J. D., Hanson, J. M., and Johnson, J. A. (2001) Biochem. Biophys. Res. Commun. 280, 286-292
14. Moinova, H. R., and Mulcahy, R. T. (1999) Biochem. Biophys. Res. Commun. 261, 661-668
15. Myhrstad, M. C., Husberg, C., Murphy, P., Nordstrom, O., Blomhoff, R., Moskaug, J. O., and Kolsto, A. B. (2001) Biochim. Biophys. Acta 1517, 212-219
16. Venugopal, R., and Jaiswal, A. K. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 14960-14965
17. Venugopal, R., and Jaiswal, A. K. (1998) Oncogene 17, 3145-3156
18. Wild, A. C., Moinova, H. R, and Mulcahy, R. T. (1999) J. Biol. Chem. 274, 33627-33636
19. Blank, V., Kim, M. J., and Andrews, N. C. (1997) Blood 89, 3925-3935
20. Dhakshinamoorthy, S., and Jaiswal, A. K. (2000) J. Biol. Chem. 275, 40134-40141
21. Toki, T., Itoh, J., Kitazawa, J., Arai, K., Hatakeyama, K., Akasaka, J., Igarashi, K., Nomura, N., Yokoyama, M., Yamamoto, M., and Ito, E. (1997) Oncogene 14, 1901-1910
22. Aoki, Y., Sato, H., Nishimura, N., Takahashi, S., Itoh, K., and Yamamoto, M. (2001) Toxicol. Appl. Pharmacol. 173, 154-160
23. Chan, K., and Kan, Y. W. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 12731-12736
24. Chan, J. Y., and Kwong, M. (2000) Biochim. Biophys. Acta 1517, 19-26
25. Chan, K., Han, X. D., and Kan, Y. W. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 4611-4616
26. Cho, H. Y., Jedlicka, A. E., Reddy, S. P., Kensler, T. W., Yamamoto, M., Zhang, L. Y., and Kleeberger, S. R. (2002) Am. J. Respir. Cell Mol. Biol. 26, 175-182
27. Enomoto, A., Itoh, K., Nagayoshi, E., Haruta, J., Kimura, T., O'Connor, T., Harada, T., and Yamamoto, M. (2001) Toxicol. Sci. 59, 169-177
28. Hayes, J. D., Chanas, S. A., Henderson, C. J., McMahon, M., Sun, C., Moffat, G. J., Wolf, C. R., and Yamamoto, M. (2000) Biochem. Soc. Trans. 28, 33-41
29. McMahon, M., Itoh, K., Yamamoto, M., Chanas, S. A., Henderson, C. J., McLellan, L. I., Wolf, C. R., Cavin, C., and Hayes, J. D. (2001) Cancer Res. 61, 3299-3307
30. Ramos-Gomez, M., Kwak, M. K., Dolan, P. M., Itoh, K., Yamamoto, M., Talalay, P., and Kensler, T. W. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 3410-3415
31. Kwak, M. K., Egner, P. A., Dolan, P. M., Ramos-Gomez, M., Groopman, J. D., Itoh, K., Yamamoto, M., and Kensler, T. W. (2001) Mutat. Res. 480-481, 305-315
32. Kensler, T. W., Curphey, T. J., Maxiutenko, Y., and Roebuck, B. D. (2000) Drug Metabol. Drug Interact. 17, 3-22
33. Itoh, K., Wakabayashi, N., Katoh, Y., Ishii, T., Igarashi, K., Engel, J. D., and Yamamoto, M. (1999) Genes Dev. 13, 76-86
34. Albagli, O., Dhordain, P., Deweindt, C., Lecocq, G., and Leprince, D. (1995) Cell Growth Differ. 6, 1193-1198
35. Soltysik-Espanola, M., Rogers, R. A., Jiang, S., Kim, T. A., Gaedigk, R., White, R. A., Avraham, H., and Avraham, S. (1999) Mol. Biol. Cell 10, 2361-2375
36. Xue, F., and Cooley, L. (1993) Cell 72, 681-693
37. Kim, I. F., Mohammadi, E., and Huang, R. C. (1999) Gene (Amst.) 228, 73-83
38. Robinson, D. N., and Cooley, L. (1997) J. Cell Biol. 138, 799-810
39. Hernandez, M. C., Andres-Barquin, P. J., Martinez, S., Bulfone, A., Rubenstein, J. L., and Israel, M. A. (1997) J. Neurosci. 17, 3038-3051
40. Bardwell, V. J., and Treisman, R. (1994) Genes Dev. 8, 1664-1677
41. Ahmad, K. F., Engel, C. K., and Prive, G. G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 12123-12128
42. Moinova, H. R., and Mulcahy, R. T. (1998) J. Biol. Chem. 273, 14683-14689
43. Melnick, A., Ahmad, K. F., Arai, S., Polinger, A., Ball, H., Borden, K. L., Carlile, G. W., Prive, G. G., and Licht, J. D. (2000) Mol. Cell. Biol. 20, 6550-6567
44. Li, X., Peng, H., Schultz, D. C., Lopez-Guisa, J. M., Rauscher, F. J., III, and Marmorstein, R. (1999) Cancer Res. 59, 5275-5282
45. Zipper, L. M., and Mulcahy, R. T. (2000) Biochem. Biophys. Res. Commun. 278, 484-492
46. Kwak, M. K., Itoh, K., Yamamoto, M., Sutter, T. R., and Kensler, T. W. (2001) Mol. Med. 7, 135-145
47. Adams, J., Kelso, R., and Cooley, L. (2000) Trends Cell Biol. 10, 17-24
48. Lecuyer, C., Dacheux, J. L., Hermand, E, Mazeman, E., Rousseaux, J., and Rousseaux-Prevost, R. (2000) Biol Reprod 63, 1801-1810
49. Espinas, M. L., Jimenez-Garcia, E., Vaquero, A., Canudas, S., Bernues, J., and Azorin, F. (1999) J. Biol. Chem. 274, 16461-16469
50. Velichkova, M., Guttman, J., Warren, C., Eng, L., Kline, K., Vogl, A. W., and Hasson, T. (2002) Cell Motil. Cytoskeleton 51, 147-164
51. Collins, T., Stone, J. R., and Williams, A. J. (2001) Mol. Cell. Biol. 21, 3609-3615
52. Kong, A. N., Owuor, E., Yu, R., Hebbar, V., Chen, C., Hu, R., and Mandlekar, S. (2001) Drug Metab. Rev. 33, 255-271
53. Huang, H. C., Nguyen, T., and Pickett, C. B. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 12475-12480
54. Lee, J. M., Hanson, J. M., Chu, W. A., and Johnson, J. A. (2001) J. Biol. Chem. 276, 20011-20016
55. Kang, K. W., Ryu, J. H., and Kim, S. G. (2000) Mol. Pharmacol. 58, 1017-1025
56. Dinkova-Kostova, A. T., Massiah, M. A., Bozak, R. E., Hicks, R. J., and Talalay, P. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 3404-3409