Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

Journal of Biological Chemistry

Volumn 278, Issue 24, 2003, Pages 21592-21600

  McMahon, Michael ^b   Itoh, Ken ^a   Yamamoto, Masayuki ^a   Hayes, John D ^c  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANTS; BIOCHEMISTRY; CELLS; GENETIC ENGINEERING;

OXIDATIVE STRESSES;

PROTEINS;

ANTIOXIDANT; PROTEASOME; PROTEIN; PROTEIN KEAP1; SULFORAPHANE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CELL LINE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE EXPRESSION; HOMEOSTASIS; LIVER CELL; MOUSE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT; REDUCTION;

ANIMALS; ANTIOXIDANTS; BINDING SITES; CARRIER PROTEINS; CELL LINE; CELL NUCLEUS; COS CELLS; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; EPITOPES; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENES, REPORTER; IMMUNOBLOTTING; MULTIENZYME COMPLEXES; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; OXIDATIVE STRESS; PLASMIDS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RESPONSE ELEMENTS; RNA, MESSENGER; SUBCELLULAR FRACTIONS; THIOCYANATES; TIME FACTORS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFECTION; UBIQUITIN;

ANIMALIA;

EID: 0037821802     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300931200     Document Type: Article

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