Gene expression profiling of NRF2-mediated protection against oxidative injury

Free Radical Biology and Medicine

Volumn 38, Issue 3, 2005, Pages 325-343

  Cho, Hye Youn ^a,b   Reddy, Sekhar P ^a   DeBiase, Andrea ^c   Yamamoto, Masayuki ^d   Kleeberger, Steven R ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c GEORGE WASHINGTON UNIVERSITY   (United States)

^d UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Antioxidant; Free radicals; Hyperoxia; Lung; Microarray; Transcription factor

Indexed keywords

ANTIOXIDANT; CELL RECEPTOR; CYTOSKELETON PROTEIN; GENE PRODUCT; HEAT SHOCK PROTEIN; TRANSCRIPTION FACTOR NRF2;

AIR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE STRUCTURE; HYPEROXIA; IMMUNOCOMPETENT CELL; LUNG INJURY; MALE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; OXYGEN TOXICITY; PRIORITY JOURNAL; UNINDEXED SEQUENCE; UPREGULATION; WILD TYPE;

ANIMALS; ANTIOXIDANTS; ATMOSPHERE EXPOSURE CHAMBERS; DNA-BINDING PROTEINS; GENE EXPRESSION PROFILING; HYPEROXIA; IMMUNOHISTOCHEMISTRY; LUNG; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; MODELS, BIOLOGICAL; NF-E2-RELATED FACTOR 2; NUCLEAR PROTEINS; OXYGEN; RNA, MESSENGER; TIME FACTORS; TRANS-ACTIVATORS;

EID: 11444261268     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.10.013     Document Type: Article

References (46)

1. B. Halliwell, J.M. Gutteridge, and C.E. Cross Free radicals, antioxidants, and human disease: where are we now? J. Lab. Clin. Med. 119 1992 598 620
2. J.W. Fahey, and P. Talalay Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia Food Chem. Toxicol. 37 1999 973 979
3. K. Itoh, T. Ishii, N. Wakabayashi, and M. Yamamoto Regulatory mechanisms of cellular response to oxidative stress Free Radic. Res. 31 1999 319 324
4. L.B. Clerch Post-transcriptional regulation of lung antioxidant enzyme gene expression Ann. N. Y. Acad. Sci. 899 2000 103 111
5. Y.S. Ho, M.S. Dey, and J.D. Crapo Antioxidant enzyme expression in rat lungs during hyperoxia Am. J. Physiol. 270 5 Pt 1 1996 L810 L818
6. J.D. Crapo Morphologic changes in pulmonary oxygen toxicity Annu. Rev. Physiol. 48 1986 721 731
7. R.J. Folz, A.M. Abushamaa, and H.B. Suliman Extracellular superoxide dismutase in the airways of transgenic mice reduces inflammation and attenuates lung toxicity following hyperoxia J. Clin. Invest. 103 1999 1055 1066
8. Y.S. Ho, R. Vincent, M.S. Dey, J.W. Slot, and J.D. Crapo Transgenic models for the study of lung antioxidant defense: enhanced manganese-containing superoxide dismutase activity gives partial protection to B6C3 hybrid mice exposed to hyperoxia Am. J. Respir. Cell Mol. Biol. 18 1998 538 547
9. M.F. Tsan, J.E. White, B. Caska, C.J. Epstein, and C.Y. Lee Susceptibility of heterozygous MnSOD gene-knockout mice to oxygen toxicity Am. J. Respir. Cell Mol. Biol. 19 1998 114 120
10. R. Barrios, Z.Z. Shi, S.V. Kala, A.L. Wiseman, S.E. Welty, G. Kala, A.A. Bahler, and M.W. Lieberman Oxygen-induced pulmonary injury in gamma-glutamyl transpeptidase-deficient mice Lung 179 2001 319 330
11. J.C. Jean, Y. Liu, L.A. Brown, R.E. Marc, E. Klings, and M. Joyce-Brady Gamma-glutamyl transpeptidase deficiency results in lung oxidant stress in normoxia Am. J. Physiol. Lung Cell Mol. Physiol. 283 2002 L766 776
12. L.E. Otterbein, J.K. Kolls, L.L. Mantell, J.L. Cook, J. Alam, and A.M. Choi Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury J. Clin. Invest. 103 1999 1047 1054
13. H.Y. Cho, A.E. Jedlicka, S.P. Reddy, L.Y. Zhang, T.W. Kensler, and S.R. Kleeberger Linkage analysis of susceptibility to hyperoxia: Nrf2 is a candidate gene Am. J. Respir. Cell Mol. Biol. 26 2002 42 51
14. K. Itoh, T. Chiba, S. Takahashi, T. Ishii, K. Igarashi, Y. Katoh, T. Oyake, N. Hayashi, K. Satoh, I. Hatayama, M. Yamamoto, and Y. Nabeshima An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements Biochem. Biophys. Res. Commun. 236 1997 313 322
15. K. Chan, and Y.W. Kan Nrf2 is essential for protection against acute pulmonary injury in mice Proc. Natl. Acad. Sci. USA 96 1999 12731 12736
16. H.Y. Cho, S.P.M. Reddy, M. Yamamoto, and S.R. Kleeberger The transcription factor NRF2 protects against pulmonary fibrosis FASEB J. 18 2004 1258 1260
17. T. Ishii, K. Itoh, S. Takahashi, H. Sato, T. Yanagawa, Y. Katoh, S. Bannai, and M. Yamamoto Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages J. Biol. Chem. 275 2000 16023 16029
18. A.Y. Shih, D.A. Johnson, G. Wong, A.D. Kraft, L. Jiang, H. Erb, J.A. Johnson, and T.H. Murphy Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress J. Neurosci. 23 2003 3394 3406
19. R. Venugopal, and A.K. Jaiswal Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes Oncogene 17 1998 3145 3156
20. H.Y. Cho, A.E. Jedlicka, S.P. Reddy, T.W. Kensler, M. Yamamoto, L.Y. Zhang, and S.R. Kleeberger Role of NRF2 in protection against hyperoxic lung injury in mice Am. J. Respir. Cell Mol. Biol. 26 2002 175 182
21. S. Buckley, B. Driscoll, L. Barsky, K. Weinberg, K. Anderson, and D. Warburton ERK activation protects against DNA damage and apoptosis in hyperoxic rat AEC2 Am. J. Physiol. Lung Cell Mol. Physiol. 277 1999 L159 L166
22. V.J. Thannickal, and B.L. Fanburg Reactive oxygen species in cell signaling Am. J. Physiol. Lung Cell Mol. Physiol. 279 2000 L1005 L1028
23. H.S. Kim, J.H. Pak, L.W. Gonzales, S.I. Feinstein, and A.B. Fisher Regulation of 1-cys peroxiredoxin expression in lung epithelial cells Am. J. Respir. Cell Mol. Biol. 27 2002 227 233
24. J.D. Hayes, E.M. Ellis, G.E. Neal, D.J. Harrison, and M.M. Manson Cellular response to cancer chemopreventive agents: contribution of the antioxidant responsive element to the adaptive response to oxidative and chemical stress Biochem. Soc. Symp. 64 1999 141 168
25. B. Moorthy, K.M. Parker, C.V. Smith, J.R. Bend, and S.E. Welty Potentiation of oxygen-induced lung injury in rats by the mechanism-based cytochrome P-450 inhibitor, 1-aminobenzotriazole J. Pharmacol. Exp. Ther. 292 2000 553 560
26. L. Sreerama, and N.E. Sladek Three different stable human breast adenocarcinoma sublines that overexpress ALDH3A1 and certain other enzymes, apparently as a consequence of constitutively upregulated gene transcription mediated by transactivated EpREs (electrophile responsive elements) present in the 5′-upstream regions of these genes Chem.-Biol. Interact. 130-132 2001 247 260
27. Y. Tsuji, H. Ayaki, S.P. Whitman, C.S. Morrow, S.V. Torti, and F.M. Torti Coordinate transcriptional and translational regulation of ferritin in response to oxidative stress Mol. Cell Biol. 16 2000 5818 5827
28. F. Yang, J.J. Coalson, H.H. Bobb, J.D. Carter, J. Banu, and A.J. Ghio Resistance of hypotransferrinemic mice to hyperoxia-induced lung injury Am. J. Physiol. Lung Cell Mol. Biol. 277 6 Pt 1 1999 L1214 L1223
29. W. Zhu, L. Song, H. Zhang, L. Matoney, E. LeCluyse, and B. Yan Dexamethasone differentially regulates expression of carboxylesterase genes in humans and rats Drug Metab. Dispos. 28 2000 186 191
30. M.K. Kwak, N. Wakabayashi, K. Itoh, H. Motohashi, M. Yamamoto, and T.W. Kensler Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway: identification of novel gene clusters for cell survival J. Biol. Chem. 278 2003 8135 8145
31. R.K. Thimmulappa, K.H. Mai, S. Srisuma, T.W. Kensler, M. Yamamoto, and S. Biswal Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray Cancer Res. 62 2002 5196 5203
32. L.D. Dwyer-Nield, B. Paigen, S.E. Porter, and A.M. Malkinson Quantitative trait locus mapping of genes regulating pulmonary PKC activity and PKC-alpha content Am. J. Physiol. Lung Cell Mol. Physiol. 279 2000 L326 L332
33. H.C. Huang, T. Nguyen, and C.B. Pickett Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription J. Biol. Chem. 277 2002 42769 42774
34. A. Hess, N. Wijayanti, A. Pathe Neuschafer-Rube, N. Katz, T. Kietzmann, and S. Immenschuh Phorbol ester-dependent activation of peroxiredoxin I gene expression via a protein kinase C, Ras, p38 mitogen-activated protein kinase signaling pathway J. Biol. Chem. 278 2003 45419 45434
35. L. Jornot, and A.F. Junod Hyperoxia, unlike phorbol ester, induces glutathione peroxidase through a protein kinase C-independent mechanism Biochem. J. 329 1997 117 123
36. S. Perkowski, J. Sun, S. Singhal, J. Santiago, G.D. Leikauf, and S.M. Albelda Gene expression profiling of the early pulmonary response to hyperoxia in mice Am. J. Respir. Cell Mol. Biol. 28 2003 682 696
37. J. Rosenbloom, W.R. Abrams, and R. Mecham Extracellular matrix 4: the elastic fiber FASEB J. 7 1993 1208 1218
38. W. Malorni, F. Iosi, F. Mirabelli, and G. Bellomo Cytoskeleton as a target in menadione-induced oxidative stress in cultured mammalian cells: alterations underlying surface bleb formation Chem.-Biol. Interact. 80 1991 217 236
39. C. Legrand, C. Gilles, J.M. Zahm, M. Polette, A.C. Buisson, H. Kaplan, P. Birembaut, and J.M. Tournier Airway epithelial cell migration dynamics; MMP-9 role in cell-extracellular matrix remodeling J. Cell Biol. 146 1999 517 529
40. T.H. Vu, and Z. Werb Matrix metalloproteinases: effectors of development and normal physiology Genes Dev. 14 2000 2123 2133
41. H.R. Lijnen Elements of the fibrinolytic system Ann. N.Y. Acad. Sci. 936 2001 226 236
42. M.A. O'Reilly, R.J. Staversky, R.H. Watkins, W.M. Maniscalco, and P.C. Keng p53-independent induction of GADD45 and GADD153 in mouse lungs exposed to hyperoxia Am. J. Physiol. Lung Cell Mol. Physiol. 278 2000 L552 L559
43. K.M. Tchou-Wong, Y. Jiang, H. Yee, J. LaRosa, T.C. Lee, A. Pellicer, J. Jagirdar, T. Gordon, J.D. Goldberg, and W.N. Rom Lung-specific expression of dominant-negative mutant p53 in transgenic mice increases spontaneous and benzo(a)pyrene-induced lung cancer Am. J. Respir. Cell Mol. Biol. 27 2002 186 193
44. M.P. Hernandez, W.P. Sullivan, and D.O. Toft The assembly and intermolecular properties of the hsp70-Hop-hsp90 molecular chaperone complex J. Biol. Chem. 277 2002 38294 38304
45. H.R. Wong, I.Y. Menendez, M.A. Ryan, A.G. Denenberg, and J.R. Wispe Increased expression of heat shock protein-70 protects A549 cells against hyperoxia Am. J. Physiol. Lung Cell. Biol. 275 4 Pt 1 1998 L836 L841
46. V.Y. Gorbacheva, D. Lindner, G.C. Sen, and D.J. Vestal The interferon (IFN)-induced GTPase, mGBP-2: role in IFN-gamma-induced murine fibroblast proliferation J. Biol. Chem. 277 2002 6080 6087