Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 7, 2004, Pages 2040-2045

  Wakabayashi, Nobunao ^a,b,c   Dinkova Kostova, Albena T ^a   Holtzclaw, W David ^a   Kang, Moon Il ^c   Kobayashi, Akira ^c   Yamamoto, Masayuki ^c   Kensler, Thomas W ^a,b   Talalay, Paul ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b The Johns Hopkins University   (United States)

^c UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ALANINE; ANTIOXIDANT; CARRIER PROTEIN; CYSTEINE; DEXAMETHASONE; DISULFIDE; DNA BINDING PROTEIN; KEAP1 PROTEIN; KELCH LIKE ECH ASSOCIATED PROTEIN 1; OXIDIZING AGENT; PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCING AGENT; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL; ANIMAL CELL; ARTICLE; BIOLOGICAL MODEL; CHEMISTRY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSKELETON; DNA RESPONSIVE ELEMENT; EMBRYO; FIBROBLAST; GENE DELETION; GENE SILENCING; GENETIC CODE; GENETICS; HUMAN; HUMAN CELL; METABOLISM; MOLECULAR GENETICS; MOUSE; MULTIGENE FAMILY; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SENSOR; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; ANTIOXIDANTS; CARRIER PROTEINS; CYSTEINE; CYTOSKELETAL PROTEINS; DISULFIDES; DNA-BINDING PROTEINS; FIBROBLASTS; GENE DELETION; GENE SILENCING; MICE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN BINDING; REDUCING AGENTS; RESPONSE ELEMENTS; TRANS-ACTIVATORS; UP-REGULATION;

ANIMALIA;

EID: 1242296811     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0307301101     Document Type: Article

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