Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of γ-glutamylcysteine synthetase

Free Radical Biology and Medicine

Volumn 32, Issue 7, 2002, Pages 650-662

  Sekhar, Konjeti R ^a   Spitz, Douglas R ^b   Harris, Stephanie ^a   Nguyen, Trung T ^a   Meredith, Michael J ^c   Holt, Jeffrey T ^d   Guis, David ^e   Marnett, Lawrence J ^d   Summar, Marshall L ^a   Freeman, Michael L ^a,d  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ARE; Free radicals; GCLC; GCLM; Glutathione; Glutathione disulfide; Indomethacin; KIAA0132; N acetylcysteine; Nrf2; NSAIDs; Resveratrol

Indexed keywords

ACETYLCYSTEINE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE DISULFIDE; IBUPROFEN; INDOMETACIN; MALEIC ACID DIETHYL ESTER; MESSENGER RNA; NONSTEROID ANTIINFLAMMATORY AGENT; RESVERATROL; TRANSCRIPTION FACTOR;

ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOTOXICITY; DEPLETION; GENE ACTIVITY; GENE EXPRESSION; GENE TRANSLOCATION; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; INCUBATION TIME; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; STEADY STATE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOTTING, NORTHERN; CARCINOMA, HEPATOCELLULAR; CARRIER PROTEINS; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DNA-BINDING PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HUMANS; IBUPROFEN; INDOMETHACIN; LEUCINE ZIPPERS; LIVER NEOPLASMS; MAP KINASE KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; TRANS-ACTIVATORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 18344387893     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)00755-4     Document Type: Article

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