-
1
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Wash. DC
-
Miki Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science (Wash. DC) 1994;266:66-71.
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
-
2
-
-
0037130887
-
Cancer Incidence in BRCA1 mutation carriers
-
Bethesda
-
Thompson D, Easton DF, and the Breast Cancer Linkage Consortium. Cancer Incidence in BRCA1 mutation carriers. J Natl Cancer Inst (Bethesda) 2002;94:1358-65.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1358-1365
-
-
Thompson, D.1
Easton, D.F.2
-
3
-
-
0032953384
-
Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas
-
Wilson CA, Ramos L, Villasenor MR, et al. Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas. Nat Genet 1999;21:236-40.
-
(1999)
Nat Genet
, vol.21
, pp. 236-240
-
-
Wilson, C.A.1
Ramos, L.2
Villasenor, M.R.3
-
4
-
-
0034607234
-
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors
-
Bethesda
-
Esteller M, Silva JM, Dominguez G, et al. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. J Natl Cancer Inst (Bethesda) 2000;92:564-9.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 564-569
-
-
Esteller, M.1
Silva, J.M.2
Dominguez, G.3
-
6
-
-
0030474170
-
Evidence for a transcription activation function of BRCA1 C-terminal region
-
Monteiro AN, August A, Hanafusa H. Evidence for a transcription activation function of BRCA1 C-terminal region. Proc Natl Acad Sci USA 1996;93:13595-9.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13595-13599
-
-
Monteiro, A.N.1
August, A.2
Hanafusa, H.3
-
7
-
-
0031830844
-
BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A
-
Anderson SF, Schlegel BP, Nakajima T, Wolpin ES, Parvin JD. BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A. Nat Genet 1998;19:254-6.
-
(1998)
Nat Genet
, vol.19
, pp. 254-256
-
-
Anderson, S.F.1
Schlegel, B.P.2
Nakajima, T.3
Wolpin, E.S.4
Parvin, J.D.5
-
8
-
-
0033967218
-
CBP/p300 interact with and function as transcriptional coactivators of BRCA1
-
Pao GM, Janknecht R, Ruffner H, Hunter T, Verma IM. CBP/p300 interact with and function as transcriptional coactivators of BRCA1. Proc Natl Acad Sci USA 2000;97:1020-5.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1020-1025
-
-
Pao, G.M.1
Janknecht, R.2
Ruffner, H.3
Hunter, T.4
Verma, I.M.5
-
9
-
-
0033609057
-
BRCA1 interacts with components of the histone deacetylase complex
-
Yarden RI, Brody LC. BRCA1 interacts with components of the histone deacetylase complex. Proc Natl Acad Sci USA 1998;96:4983-8.
-
(1998)
Proc Natl Acad Sci USA
, vol.96
, pp. 4983-4988
-
-
Yarden, R.I.1
Brody, L.C.2
-
10
-
-
0032532543
-
BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells
-
Wang Q, Zhang H, Kajino K, Greene MI. BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells. Oncogene 1998;17:1939-48.
-
(1998)
Oncogene
, vol.17
, pp. 1939-1948
-
-
Wang, Q.1
Zhang, H.2
Kajino, K.3
Greene, M.I.4
-
11
-
-
0032478085
-
BRCA1 regulates p53-dependent gene expression
-
Ouichi T, Monteiro AN, August A, Aaronson SA, Hanafusa H. BRCA1 regulates p53-dependent gene expression. Proc Natl Acad Sci USA 1998;95:2302-6.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2302-2306
-
-
Ouichi, T.1
Monteiro, A.N.2
August, A.3
Aaronson, S.A.4
Hanafusa, H.5
-
12
-
-
0035804228
-
Role of direct interaction in BRCA1 inhibition of estrogen receptor activity
-
Fan S, Wang J-A, Ma YX, et al. Role of direct interaction in BRCA1 inhibition of estrogen receptor activity. Oncogene 2001;20:77-87.
-
(2001)
Oncogene
, vol.20
, pp. 77-87
-
-
Fan, S.1
Wang, J.-A.2
Ma, Y.X.3
-
13
-
-
0035857073
-
Mutant BRCA1 genes antagonize phenotype of wild-type BRCA1
-
Fan S, Yuan R-Q, Ma Y-X, Meng Q, Goldberg ID, Rosen EM. Mutant BRCA1 genes antagonize phenotype of wild-type BRCA1. Oncogene 2001;20:8215-35.
-
(2001)
Oncogene
, vol.20
, pp. 8215-8235
-
-
Fan, S.1
Yuan, R.-Q.2
Ma, Y.-X.3
Meng, Q.4
Goldberg, I.D.5
Rosen, E.M.6
-
14
-
-
0032507879
-
BRCA1 as a human prostate tumor suppressor, modulation of proliferation, damage responses, and expression of regulatory proteins
-
Fan S, Wang J-A, Yuan R-Q, et al. BRCA1 as a human prostate tumor suppressor, modulation of proliferation, damage responses, and expression of regulatory proteins. Oncogene 1998;16:3069-83.
-
(1998)
Oncogene
, vol.16
, pp. 3069-3083
-
-
Fan, S.1
Wang, J.-A.2
Yuan, R.-Q.3
-
15
-
-
0242721645
-
BRCA1 inhibition of telomerase activity in cultured cells
-
Xiong J, Fan S, Meng Q, et al. BRCA1 inhibition of telomerase activity in cultured cells. Mol Cell Biol 2003;23:8668-90.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8668-8690
-
-
Xiong, J.1
Fan, S.2
Meng, Q.3
-
16
-
-
0033106326
-
2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells
-
2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells. Mol Cell 1999;3:389-95.
-
(1999)
Mol Cell
, vol.3
, pp. 389-395
-
-
Xu, X.1
Weaver, Z.2
Linke, S.P.3
-
17
-
-
0035503605
-
Altered gene expression pattern in cultured human breast cancer cells treated with hepatocyte growth factor/scatter factor (HGF/SF) in the setting of DNA damage
-
Yuan R-Q, Fan S, Achary M, Stewart DM, Goldberg ID, Rosen EM. Altered gene expression pattern in cultured human breast cancer cells treated with hepatocyte growth factor/scatter factor (HGF/SF) in the setting of DNA damage. Cancer Res 2001;61:8022-31.
-
(2001)
Cancer Res
, vol.61
, pp. 8022-8031
-
-
Yuan, R.-Q.1
Fan, S.2
Achary, M.3
Stewart, D.M.4
Goldberg, I.D.5
Rosen, E.M.6
-
18
-
-
0036845144
-
Diindolylmethane alters gene expression in human keratinocytes in vitro
-
Carter TH, Liu K, Ralph W Jr, et al. Diindolylmethane alters gene expression in human keratinocytes in vitro. J Nutr 2002;132:3314-24.
-
(2002)
J Nutr
, vol.132
, pp. 3314-3324
-
-
Carter, T.H.1
Liu, K.2
Ralph Jr., W.3
-
19
-
-
0037427084
-
Role of BRCA1 in heat shock response
-
Ma YX, Fan S, Xiong J, et al. Role of BRCA1 in heat shock response. Oncogene 2003;22:10-27.
-
(2003)
Oncogene
, vol.22
, pp. 10-27
-
-
Ma, Y.X.1
Fan, S.2
Xiong, J.3
-
20
-
-
0037192626
-
Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to up-regulate antioxidant response element-mediated expression and antioxidant induction of NAD-(P)H:quinone oxidoreductase 1 gene
-
Bloom D, Dhakshinamoorthy S, Jaiswal AK. Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to up-regulate antioxidant response element-mediated expression and antioxidant induction of NAD-(P)H:quinone oxidoreductase 1 gene. Oncogene 2002;21:2191-200.
-
(2002)
Oncogene
, vol.21
, pp. 2191-2200
-
-
Bloom, D.1
Dhakshinamoorthy, S.2
Jaiswal, A.K.3
-
22
-
-
0037268531
-
Cognition impairment in the genetic model of aging klotho gene mutant mice, a role of oxidative stress
-
Nagai T, Yamada K, Kim HC, et al. Cognition impairment in the genetic model of aging klotho gene mutant mice, a role of oxidative stress. FASEB J 2003;17:50-2.
-
(2003)
FASEB J
, vol.17
, pp. 50-52
-
-
Nagai, T.1
Yamada, K.2
Kim, H.C.3
-
23
-
-
0142125350
-
New insights into Parkinson's disease
-
Chung KK, Dawson VL, Dawson TM. New insights into Parkinson's disease. J Neurol 2003;250 Suppl 3:III:15-24.
-
(2003)
J Neurol
, vol.250
, Issue.3 SUPPL. 3
, pp. 15-24
-
-
Chung, K.K.1
Dawson, V.L.2
Dawson, T.M.3
-
24
-
-
0346365372
-
Glutathione S-transferase pi amplification is associated with cisplatin resistance in head and neck squamous cell carcinoma cell lines and primary tumors
-
Cullen KJ, Newkirk KA, Schumaker LM, Aldosari N, Rone JD, Haddad BR. Glutathione S-transferase pi amplification is associated with cisplatin resistance in head and neck squamous cell carcinoma cell lines and primary tumors. Cancer Res 2003;63:8097-102.
-
(2003)
Cancer Res
, vol.63
, pp. 8097-8102
-
-
Cullen, K.J.1
Newkirk, K.A.2
Schumaker, L.M.3
Aldosari, N.4
Rone, J.D.5
Haddad, B.R.6
-
25
-
-
0035018530
-
Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci
-
Huber LJ, Yang TW, Sarkisian CJ, Master SR, Deng CX, Chodosh LA. Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci. Mol Cell Biol 2001;21:4005-15.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4005-4015
-
-
Huber, L.J.1
Yang, T.W.2
Sarkisian, C.J.3
Master, S.R.4
Deng, C.X.5
Chodosh, L.A.6
-
26
-
-
0037188479
-
BRCA1 transcriptionally regulates genes involved in breast tumorigenesis
-
Welcsh PL, Lee MK, Gonzalez-Hernandez RM, et al. BRCA1 transcriptionally regulates genes involved in breast tumorigenesis. Proc Natl Acad Sci USA 2002;28:7560-5.
-
(2002)
Proc Natl Acad Sci USA
, vol.28
, pp. 7560-7565
-
-
Welcsh, P.L.1
Lee, M.K.2
Gonzalez-Hernandez, R.M.3
-
27
-
-
0034723347
-
BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression
-
MacLachlan TK, Somasundaram K, Sgagias M, et al. BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression. J Biol Chem 2000;275:2777-85.
-
(2000)
J Biol Chem
, vol.275
, pp. 2777-2785
-
-
MacLachlan, T.K.1
Somasundaram, K.2
Sgagias, M.3
-
28
-
-
0035854674
-
BRCA1 is a selective coactivator of 14-3-3 sigma gene transcription in mouse embryonic stem cells
-
Aprelikova O, Pace AJ, Fang B, Koller BH, Liu ET. BRCA1 is a selective coactivator of 14-3-3 sigma gene transcription in mouse embryonic stem cells. J Biol Chem 2001;76:25647-50.
-
(2001)
J Biol Chem
, vol.76
, pp. 25647-25650
-
-
Aprelikova, O.1
Pace, A.J.2
Fang, B.3
Koller, B.H.4
Liu, E.T.5
-
29
-
-
0037763721
-
Regulatory mechanisms controlling gene expression mediated by the antioxidant response element
-
Nguyen T, Sherratt PJ, Pickett CB. Regulatory mechanisms controlling gene expression mediated by the antioxidant response element. Annu Rev Pharmacol Toxicol 2003;43:233-60.
-
(2003)
Annu Rev Pharmacol Toxicol
, vol.43
, pp. 233-260
-
-
Nguyen, T.1
Sherratt, P.J.2
Pickett, C.B.3
-
30
-
-
0034724914
-
Structural organization of the microsomal glutathione S-transferase gene (MGST1) on chromosome 12p13.1-13.2. Identification of the correct promoter region and demonstration of transcriptional regulation in response to oxidative stress
-
Kelner MJ, Bagnell RD, Montoya MA, Estes LA, Forsberg L, Morgenstern R. Structural organization of the microsomal glutathione S-transferase gene (MGST1) on chromosome 12p13.1-13.2. Identification of the correct promoter region and demonstration of transcriptional regulation in response to oxidative stress. J Biol Chem 2000;275:13000-6.
-
(2000)
J Biol Chem
, vol.275
, pp. 13000-13006
-
-
Kelner, M.J.1
Bagnell, R.D.2
Montoya, M.A.3
Estes, L.A.4
Forsberg, L.5
Morgenstern, R.6
-
31
-
-
0037106099
-
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
-
Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M, Biswal S. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res 2002;62:5196-203.
-
(2002)
Cancer Res
, vol.62
, pp. 5196-5203
-
-
Thimmulappa, R.K.1
Mai, K.H.2
Srisuma, S.3
Kensler, T.W.4
Yamamoto, M.5
Biswal, S.6
-
32
-
-
18544372595
-
BRCA2 function in DNA binding and recombination from a BRCA2-DSSI-ssDNA structure
-
Wash. DC
-
Yang H, Jeffrey PD, Miller J, et al. BRCA2 function in DNA binding and recombination from a BRCA2-DSSI-ssDNA structure. Science 2002 (Wash. DC);297:1837-48.
-
(2002)
Science
, vol.297
, pp. 1837-1848
-
-
Yang, H.1
Jeffrey, P.D.2
Miller, J.3
-
33
-
-
0033061265
-
The diverse role of selenium within selenoproteins, a review
-
Holben DH, Smith AM. The diverse role of selenium within selenoproteins, a review. J Am Diet Assoc 1999;99:836-43.
-
(1999)
J Am Diet Assoc
, vol.99
, pp. 836-843
-
-
Holben, D.H.1
Smith, A.M.2
-
34
-
-
0036007313
-
Role of NRF2 in protection against hyperoxic lung injury in mice
-
Cho HY, Jedlicka AE, Reddy SP, et al. Role of NRF2 in protection against hyperoxic lung injury in mice. Am J Respir Cell Mol Biol 2002;26:175-82.
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 175-182
-
-
Cho, H.Y.1
Jedlicka, A.E.2
Reddy, S.P.3
-
35
-
-
0035853157
-
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
-
Ramos-Gomez M, Kwak MK, Dolan PM, et al. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc Natl Acad Sci USA 2001;98:3410-5.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3410-3415
-
-
Ramos-Gomez, M.1
Kwak, M.K.2
Dolan, P.M.3
-
36
-
-
0035025124
-
Mechanisms of carcinogenesis, focus on oxidative stress and electron transfer
-
Kovacic P, Jacintho ID. Mechanisms of carcinogenesis, focus on oxidative stress and electron transfer. Curr Med Chem 2001;8:773-96.
-
(2001)
Curr Med Chem
, vol.8
, pp. 773-796
-
-
Kovacic, P.1
Jacintho, I.D.2
-
37
-
-
0345410965
-
Mammalian small stress proteins protect against oxidative stress through their ability to increase glucose-6-phosphate dehydrogenase activity and by maintaining optimal cellular detoxifying machinery
-
Preville X, Salvemini F, Giraud S, et al. Mammalian small stress proteins protect against oxidative stress through their ability to increase glucose-6-phosphate dehydrogenase activity and by maintaining optimal cellular detoxifying machinery. Exp Cell Res 1999;247:61-78.
-
(1999)
Exp Cell Res
, vol.247
, pp. 61-78
-
-
Preville, X.1
Salvemini, F.2
Giraud, S.3
-
38
-
-
0028828673
-
Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice
-
Lane TF, Deng C, Elson A, Lyu MS, Kozak CA, Leder P. Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice. Genes Dev 1995;9:2712-22.
-
(1995)
Genes Dev
, vol.9
, pp. 2712-2722
-
-
Lane, T.F.1
Deng, C.2
Elson, A.3
Lyu, M.S.4
Kozak, C.A.5
Leder, P.6
-
39
-
-
0031569873
-
Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues
-
Rajan JV, Marquis ST, Gardner HP, Chodosh LD. Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues. Devel Biol 1997;184:385-401.
-
(1997)
Devel Biol
, vol.184
, pp. 385-401
-
-
Rajan, J.V.1
Marquis, S.T.2
Gardner, H.P.3
Chodosh, L.D.4
-
40
-
-
0029822055
-
Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammalian epithelial cells
-
Rajan JV, Wang M, Marquis ST, Chodosh LA. Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammalian epithelial cells. Proc Natl Acad Sci USA 1996;93:3078-83.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3078-3083
-
-
Rajan, J.V.1
Wang, M.2
Marquis, S.T.3
Chodosh, L.A.4
-
41
-
-
0037130478
-
Brca1 regulates in vitro differentiation of mammary epithelial cells
-
Kubista M, Rosner M, Kubista E, Bernaschek G, Hengstschlager M. Brca1 regulates in vitro differentiation of mammary epithelial cells. Oncogene 2002;21:4747-56.
-
(2002)
Oncogene
, vol.21
, pp. 4747-4756
-
-
Kubista, M.1
Rosner, M.2
Kubista, E.3
Bernaschek, G.4
Hengstschlager, M.5
-
42
-
-
0029068315
-
Germline BRCA1 mutations and loss of the wild-type allele in tumors from families with early onset breast and ovarian cancer
-
Merajver SD, Frank TS, Xu J, et al. Germline BRCA1 mutations and loss of the wild-type allele in tumors from families with early onset breast and ovarian cancer. Clin Cancer Res 1995;1:539-44.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 539-544
-
-
Merajver, S.D.1
Frank, T.S.2
Xu, J.3
-
43
-
-
1842364973
-
Localization of BRCA1 and a splice variant identifies the nuclear localization signal
-
Thakur S, Zhang HB, Peng Y, et al. Localization of BRCA1 and a splice variant identifies the nuclear localization signal. Mol Cell Biol 1997;17:444-52.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 444-452
-
-
Thakur, S.1
Zhang, H.B.2
Peng, Y.3
-
44
-
-
0042941431
-
Haplo-insufficiency of BRCA1 in sporadic breast cancer
-
Staff S, Isola J, Tanner M. Haplo-insufficiency of BRCA1 in sporadic breast cancer. Cancer Res 2003;63:4978-83.
-
(2003)
Cancer Res
, vol.63
, pp. 4978-4983
-
-
Staff, S.1
Isola, J.2
Tanner, M.3
|