Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

Molecular and Cellular Biology

Volumn 23, Issue 22, 2003, Pages 8137-8151

  Zhang, Donna D ^a   Hannink, Mark ^a  

^a University of Missouri   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYSTEINE; CYTOPLASM PROTEIN; PROTEASOME; PROTEIN KEAP1; SULFORAPHANE; TERT BUTYL HYDROXYQUINONE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NRF2; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CANCER PREVENTION; CELL NUCLEUS; CELL STRAIN 3T3; CELL STRAIN COS1; CHEMOPROPHYLAXIS; CONTROLLED STUDY; CYTOPLASM; GENE REPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PROCESSING; REPORTER GENE; UBIQUITINATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTICARCINOGENIC AGENTS; CARRIER PROTEINS; CELL LINE; COS CELLS; CYSTEINE; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; MICE; MUTAGENESIS; NF-E2-RELATED FACTOR 2; NIH 3T3 CELLS; OXIDATIVE STRESS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE DELETION; THIOCYANATES; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; UBIQUITIN;

ANIMALIA;

EID: 0242580049     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.22.8137-8151.2003     Document Type: Article

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