-
1
-
-
0030022346
-
EGF or PDGF receptors activate atypical PKCλ through phosphatidylinositol 3-kinase
-
Akimoto K, Takahashi R, Moriya S, Nishioka N, Takayanagi J, Kimura K, Fukui Y, Osada S, Mizuno K, Hirai S, Kazlauskas A, and Ohno S. EGF or PDGF receptors activate atypical PKCλ through phosphatidylinositol 3-kinase. EMBO J 15: 788-798, 1996.
-
(1996)
EMBO J
, vol.15
, pp. 788-798
-
-
Akimoto, K.1
Takahashi, R.2
Moriya, S.3
Nishioka, N.4
Takayanagi, J.5
Kimura, K.6
Fukui, Y.7
Osada, S.8
Mizuno, K.9
Hirai, S.10
Kazlauskas, A.11
Ohno, S.12
-
2
-
-
0037377144
-
Heme activates the heme oxygenase- 1 gene in renal epithelial cells by stabilizing Nrf2
-
Alam J, Killeen E, Gong P, Naquin R, Hu B, Stewart D, Ingelfinger JR, and Nath KA. Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2. Am J Physiol Renal Physiol 284: F546-F554, 2003.
-
(2003)
Am J Physiol Renal Physiol
, vol.284
-
-
Alam, J.1
Killeen, E.2
Gong, P.3
Naquin, R.4
Hu, B.5
Stewart, D.6
Ingelfinger, J.R.7
Nath, K.A.8
-
3
-
-
0033543566
-
Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase- 1 gene
-
Alam J, Stewart D, Touchard C, Boinapally S, Choi AM, and Cook JL. Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene. J Biol Chem 274: 26071-26078, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 26071-26078
-
-
Alam, J.1
Stewart, D.2
Touchard, C.3
Boinapally, S.4
Choi, A.M.5
Cook, J.L.6
-
4
-
-
0034623211
-
Mechanism of heme oxygenase-1 gene activation by cadmium in MCF- 7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor
-
Alam J, Wicks C, Stewart D, Gong P, Touchard C, Otterbein S, Choi AM, Burow ME, and Tou J. Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor. J Biol Chem 275: 27694-27702, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 27694-27702
-
-
Alam, J.1
Wicks, C.2
Stewart, D.3
Gong, P.4
Touchard, C.5
Otterbein, S.6
Choi, A.M.7
Burow, M.E.8
Tou, J.9
-
5
-
-
0034617281
-
A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Cζ (PKCζ) and PKC-related kinase 2 by PDK1
-
Balendran A, Biondi RM, Cheung PC, Casamayor A, Deak M, and Alessi DR. A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Cζ (PKCζ) and PKC-related kinase 2 by PDK1. J Biol Chem 275: 20806-20813, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 20806-20813
-
-
Balendran, A.1
Biondi, R.M.2
Cheung, P.C.3
Casamayor, A.4
Deak, M.5
Alessi, D.R.6
-
6
-
-
0343446113
-
Lipid metabolite involvement in the activation of the human heme oxygenase-1 gene
-
Basu-Modak S, Luscher P, and Tyrrell RM. Lipid metabolite involvement in the activation of the human heme oxygenase-1 gene. Free Radic Biol Med 20: 887-897, 1996.
-
(1996)
Free Radic Biol Med
, vol.20
, pp. 887-897
-
-
Basu-Modak, S.1
Luscher, P.2
Tyrrell, R.M.3
-
7
-
-
0027178812
-
Protein kinase C ζ isoform is critical for mitogenic signal transduction
-
Berra E, Diaz-Meco MT, Dominguez I, Municio MM, Sanz L, Lozano J, Chapkin RS, and Moseat J. Protein kinase C ζ isoform is critical for mitogenic signal transduction. Cell 74: 555-563, 1993
-
(1993)
Cell
, vol.74
, pp. 555-563
-
-
Berra, E.1
Diaz-Meco, M.T.2
Dominguez, I.3
Municio, M.M.4
Sanz, L.5
Lozano, J.6
Chapkin, R.S.7
Moseat, J.8
-
8
-
-
0033579464
-
Sequence and structure-based prediction of eukaryotic protein phosphorylation sites
-
Blom N, Gammeltoft S, and Brunak S. Sequence and structure-based prediction of eukaryotic protein phosphorylation sites. J Mol Biol 294: 1351-1362, 1999.
-
(1999)
J Mol Biol
, vol.294
, pp. 1351-1362
-
-
Blom, N.1
Gammeltoft, S.2
Brunak, S.3
-
9
-
-
0037192626
-
Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H: Quinone oxidoreductase 1 gene
-
Bloom D, Dhakshinamoorthy S, and Jaiswal AK. Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene. Oncogene 21: 2191-2200, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 2191-2200
-
-
Bloom, D.1
Dhakshinamoorthy, S.2
Jaiswal, A.K.3
-
10
-
-
0034672595
-
Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein
-
Chan JY and Kwong M. Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein. Biochim Biophys Acta 1517: 19-26, 2000.
-
(2000)
Biochim Biophys Acta
, vol.1517
, pp. 19-26
-
-
Chan, J.Y.1
Kwong, M.2
-
11
-
-
13044304201
-
Nrf2 is essential for protection against acute pulmonary injury in mice
-
Chan K and Kan YW. Nrf2 is essential for protection against acute pulmonary injury in mice. Proc Natl Acad Sci USA 96: 12731-12736, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12731-12736
-
-
Chan, K.1
Kan, Y.W.2
-
12
-
-
0035836698
-
An important function of Nrf2 in combating oxidative stress: Detoxification of acetaminophen
-
Chan K, Han XD, and Kan YW. An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen. Proc Natl Acad Sci USA 98: 4611-4616, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4611-4616
-
-
Chan, K.1
Han, X.D.2
Kan, Y.W.3
-
13
-
-
0035963293
-
Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H: Quinone oxidoreductase 1 gene
-
Dhakshinamoorthy S and Jaiswal AK. Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H: quinone oxidoreductase1 gene. Oncogene 20: 3906-3917, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 3906-3917
-
-
Dhakshinamoorthy, S.1
Jaiswal, A.K.2
-
14
-
-
0030572696
-
The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C
-
Diaz-Meco MT, Municio MM, Frutos S, Sanchez P, Lozano J, Sanz L, and Moseat J. The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C. Cell 86: 777-786, 1996.
-
(1996)
Cell
, vol.86
, pp. 777-786
-
-
Diaz-Meco, M.T.1
Municio, M.M.2
Frutos, S.3
Sanchez, P.4
Lozano, J.5
Sanz, L.6
Moseat, J.7
-
15
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap 1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K, Wakabayashi N, Katoh Y, Yamamoto M, and Talalay P. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc Natl Acad Sci USA 99: 11908-11913, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
Yamamoto, M.7
Talalay, P.8
-
16
-
-
0030846622
-
Ceramide-induced translocation of protein kinase Cζ in primary cultures of astrocytes
-
Galve-Roperh I, Haro A, and Diaz-Laviada I. Ceramide-induced translocation of protein kinase Cζ in primary cultures of astrocytes. FEBS Lett 415: 271-274, 1997.
-
(1997)
FEBS Lett
, vol.415
, pp. 271-274
-
-
Galve-Roperh, I.1
Haro, A.2
Diaz-Laviada, I.3
-
17
-
-
0037044791
-
Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription
-
Huang HC, Nguyen T, and Pickett CB. Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription. J Biol Chem 277: 42769-42774, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 42769-42774
-
-
Huang, H.C.1
Nguyen, T.2
Pickett, C.B.3
-
18
-
-
0033731182
-
Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2
-
Huang HC, Nguyen T, and Pickett CB. Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2. Proc Natl Acad Sci USA 97: 12475-12480, 2000.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 12475-12480
-
-
Huang, H.C.1
Nguyen, T.2
Pickett, C.B.3
-
19
-
-
0034717329
-
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
-
Ishii T, Itoh K, Takahashi S, Sato H, Yanagawa T, Katoh Y, Bannai S, and Yamamoto M. Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J Biol Chem 275: 16023-16029, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 16023-16029
-
-
Ishii, T.1
Itoh, K.2
Takahashi, S.3
Sato, H.4
Yanagawa, T.5
Katoh, Y.6
Bannai, S.7
Yamamoto, M.8
-
20
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, Oyake T, Hayashi N, Satoh K, Hatayama I, Yamamoto M, and Nabeshima Y. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun 236: 313-322, 1997.
-
(1997)
Biochem Biophys Res Commun
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
Satoh, K.9
Hatayama, I.10
Yamamoto, M.11
Nabeshima, Y.12
-
21
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh 2 domain
-
Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, and Yamamoto M. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 13: 76-86, 1999.
-
(1999)
Genes Dev
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
22
-
-
0032487494
-
An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3
-
Izumi Y, Hirose T, Tamai Y, Hirai S, Nagashima Y, Fujimoto T, Tabuse Y, Kemphues KJ, and Ohno S. An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3. J Cell Biol 143: 95-106, 1998.
-
(1998)
J Cell Biol
, vol.143
, pp. 95-106
-
-
Izumi, Y.1
Hirose, T.2
Tamai, Y.3
Hirai, S.4
Nagashima, Y.5
Fujimoto, T.6
Tabuse, Y.7
Kemphues, K.J.8
Ohno, S.9
-
23
-
-
0033800922
-
Regulation of genes encoding NAD(P)H: Quinone oxidoreductases
-
Jaiswal AK. Regulation of genes encoding NAD(P)H:quinone oxidoreductases. Free Radic Biol Med 29: 254-262, 2000.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 254-262
-
-
Jaiswal, A.K.1
-
24
-
-
0034253536
-
The cell-polarity protein Par 6 links Par3 and atypical protein kinase C to Cdc42
-
Joberty G, Petersen C, Gao L, and Macara IG. The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat Cell Biol 2: 531-539, 2000.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 531-539
-
-
Joberty, G.1
Petersen, C.2
Gao, L.3
Macara, I.G.4
-
25
-
-
0036319473
-
Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice
-
Johnson DA, Andrews GK, Xu W, and Johnson JA. Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice. J Neurochem 81: 1233-1241, 2002.
-
(2002)
J Neurochem
, vol.81
, pp. 1233-1241
-
-
Johnson, D.A.1
Andrews, G.K.2
Xu, W.3
Johnson, J.A.4
-
26
-
-
0032528288
-
Transcriptional activation of c-fos by oncogenic Ha-Ras in mouse mammary epithelial cells requires the combined activities of PKC-λ, ε and ζ
-
Kampfer S, Hellbert K, Villunger A, Doppler W, Baier G, Grunicke HH, and Uberall F. Transcriptional activation of c-fos by oncogenic Ha-Ras in mouse mammary epithelial cells requires the combined activities of PKC-λ, ε and ζ. EMBO J 17: 4046-4055, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 4046-4055
-
-
Kampfer, S.1
Hellbert, K.2
Villunger, A.3
Doppler, W.4
Baier, G.5
Grunicke, H.H.6
Uberall, F.7
-
27
-
-
0035827505
-
Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR- 32 human neuroblastoma cells
-
Lee JM, Hanson JM, Chu WA, and Johnson JA. Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells. J Biol Chem 276: 20011-20016, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 20011-20016
-
-
Lee, J.M.1
Hanson, J.M.2
Chu, W.A.3
Johnson, J.A.4
-
28
-
-
0000202186
-
A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac 1 and aPKC signalling and cell polarity
-
Lin D, Edwards AS, Fawcett JP, Mbamalu G, Scott JD, and Pawson T. A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity. Nat Cell Biol 2: 540-547, 2000.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 540-547
-
-
Lin, D.1
Edwards, A.S.2
Fawcett, J.P.3
Mbamalu, G.4
Scott, J.D.5
Pawson, T.6
-
29
-
-
0031735363
-
γ-glutamylcysteine synthetase: mRNA stabilization and independent subunit transcription by 4-hydroxy-2-nonenal
-
Liu RM, Gao L, Choi J, and Forman HJ. γ-Glutamylcysteine synthetase: mRNA stabilization and independent subunit transcription by 4-hydroxy-2-nonenal. Am J Physiol Lung Cell Mol Physiol 275: L861-L869, 1998.
-
(1998)
Am J Physiol Lung Cell Mol Physiol
, vol.275
-
-
Liu, R.M.1
Gao, L.2
Choi, J.3
Forman, H.J.4
-
30
-
-
0022401902
-
1.5 kb mRNA abundantly expressed in rat tumors encodes a 37 kilodalton protein in vitro
-
Maehara Y, Fujiyoshi T, Takahashi K, Yamamoto M, and Endo H. 1.5 kb mRNA abundantly expressed in rat tumors encodes a 37 kilodalton protein in vitro. Biochem Biophys Res Commun 131: 800-805, 1985.
-
(1985)
Biochem Biophys Res Commun
, vol.131
, pp. 800-805
-
-
Maehara, Y.1
Fujiyoshi, T.2
Takahashi, K.3
Yamamoto, M.4
Endo, H.5
-
31
-
-
0023731036
-
Hemeoxygenase: Function, multiplicity, regulatory mechanisms, and clinical applications
-
Maines MD. Hemeoxygenase: function, multiplicity, regulatory mechanisms, and clinical applications. FASEB J 2: 2557-2568, 1988.
-
(1988)
FASEB J
, vol.2
, pp. 2557-2568
-
-
Maines, M.D.1
-
32
-
-
0034533061
-
Inhibition of growth-factor-induced phosphorylation and activation of protein kinase B/Akt by atypical protein kinase C in breast cancer cells
-
Mao M, Fang X, Lu Y, Lapushin R, Bast RC Jr, and Mills GB. Inhibition of growth-factor-induced phosphorylation and activation of protein kinase B/Akt by atypical protein kinase C in breast cancer cells. Biochem J 352: 475-482, 2000.
-
(2000)
Biochem J
, vol.352
, pp. 475-482
-
-
Mao, M.1
Fang, X.2
Lu, Y.3
Lapushin, R.4
Bast R.C., Jr.5
Mills, G.B.6
-
33
-
-
0030974478
-
hMAF, a small human transcription factor that heterodimerizes specifically with Nrf 1 and Nrf2
-
Marini MG, Chan K, Casula L, Kan YW, Cao A, and Moi P. hMAF, a small human transcription factor that heterodimerizes specifically with Nrf1 and Nrf2. J Biol Chem 272: 16490-16497, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 16490-16497
-
-
Marini, M.G.1
Chan, K.2
Casula, L.3
Kan, Y.W.4
Cao, A.5
Moi, P.6
-
34
-
-
27644504484
-
Modulating protein kinase C signal transduction
-
Mochly-Rosen D and Kauvar LM. Modulating protein kinase C signal transduction. Adv Pharmacol 44: 91-145, 1998.
-
(1998)
Adv Pharmacol
, vol.44
, pp. 91-145
-
-
Mochly-Rosen, D.1
Kauvar, L.M.2
-
35
-
-
0028061444
-
Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the β-globin locus control region
-
Moi P, Chan K, Asunis I, Cao A, and Kan YW. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the β-globin locus control region. Proc Natl Acad Sci USA 91: 9926-9930, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9926-9930
-
-
Moi, P.1
Chan, K.2
Asunis, I.3
Cao, A.4
Kan, Y.W.5
-
36
-
-
0030836301
-
Atypical protein kinase Cι protects human leukemia cells against drug-induced apoptosis
-
Murray NR and Fields AP. Atypical protein kinase Cι protects human leukemia cells against drug-induced apoptosis. J Biol Chem 272: 27521-27524, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 27521-27524
-
-
Murray, N.R.1
Fields, A.P.2
-
37
-
-
0035476981
-
Regulation of phospholipase D isoenzymes by transforming Ras and atypical protein kinase C-ι
-
Mwanjewe J, Spitaler M, Ebner M, Windegger M, Geiger M, Kampfer S, Hofmann J, Uberall F, and Grunicke HH. Regulation of phospholipase D isoenzymes by transforming Ras and atypical protein kinase C-ι. Biochem J 359: 211-217, 2001.
-
(2001)
Biochem J
, vol.359
, pp. 211-217
-
-
Mwanjewe, J.1
Spitaler, M.2
Ebner, M.3
Windegger, M.4
Geiger, M.5
Kampfer, S.6
Hofmann, J.7
Uberall, F.8
Grunicke, H.H.9
-
38
-
-
0027535742
-
Activation of the ζ isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate
-
Nakanishi H, Brewer KA, and Exton JH. Activation of the ζ isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 268: 13-16, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 13-16
-
-
Nakanishi, H.1
Brewer, K.A.2
Exton, J.H.3
-
39
-
-
0013282861
-
Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element: Degradation of Nrf 2 by the 26S proteasome
-
Nguyen T, Sherratt PJ, Huang HC, Yang CS, and Pickett CB. Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element: degradation of Nrf2 by the 26S proteasome. J Biol Chem 278: 4536-4541, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 4536-4541
-
-
Nguyen, T.1
Sherratt, P.J.2
Huang, H.C.3
Yang, C.S.4
Pickett, C.B.5
-
40
-
-
0029060391
-
Protein kinase C and lipid signaling for sustained cellular responses
-
Nishizuka Y. Protein kinase C and lipid signaling for sustained cellular responses. FASEB J 9: 484-496, 1995.
-
(1995)
FASEB J
, vol.9
, pp. 484-496
-
-
Nishizuka, Y.1
-
41
-
-
0023764824
-
The molecular heterogeneity of protein kinase C and its implications for cellular regulation
-
Nishizuka Y. The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334: 661-665, 1988.
-
(1988)
Nature
, vol.334
, pp. 661-665
-
-
Nishizuka, Y.1
-
42
-
-
0021227676
-
The role of protein kinase C in cell surface signal transduction and tumour promotion
-
Nishizuka Y. The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature 308: 693-698, 1984.
-
(1984)
Nature
, vol.308
, pp. 693-698
-
-
Nishizuka, Y.1
-
43
-
-
0031574305
-
Cooperative induction of c-fos and heme oxygenase gene products under oxidative stress in human fibroblastic cells
-
Numazawa S, Yamada H, Furusho A, Nakahara T, Oguro T, and Yoshida T. Cooperative induction of c-fos and heme oxygenase gene products under oxidative stress in human fibroblastic cells. Exp Cell Res 237: 434-444, 1997.
-
(1997)
Exp Cell Res
, vol.237
, pp. 434-444
-
-
Numazawa, S.1
Yamada, H.2
Furusho, A.3
Nakahara, T.4
Oguro, T.5
Yoshida, T.6
-
44
-
-
0032463530
-
The expression of heme oxygenase-1 gene responded to oxidative stress produced by phorone, a glutathione depletor, in the rat liver; the relevance to activation of c-Jun N-terminal kinase
-
Oguro T, Hayashi M, Nakajo S, Numazawa S, and Yoshida T. The expression of heme oxygenase-1 gene responded to oxidative stress produced by phorone, a glutathione depletor, in the rat liver; the relevance to activation of c-Jun N-terminal kinase. J Pharmacol Exp Ther 287: 773-778, 1998.
-
(1998)
J Pharmacol Exp Ther
, vol.287
, pp. 773-778
-
-
Oguro, T.1
Hayashi, M.2
Nakajo, S.3
Numazawa, S.4
Yoshida, T.5
-
45
-
-
0032422051
-
HNE interacts directly with JNK isoforms in human hepatic stellate cells
-
Parola M, Robino G, Marra F, Pinzani M, Bellomo G, Leonarduzzi G, Chiarugi P, Camandola S, Poli G, Waeg G, Gentilini P, and Dianzani MU. HNE interacts directly with JNK isoforms in human hepatic stellate cells. J Clin Invest 102: 1942-1950, 1998.
-
(1998)
J Clin Invest
, vol.102
, pp. 1942-1950
-
-
Parola, M.1
Robino, G.2
Marra, F.3
Pinzani, M.4
Bellomo, G.5
Leonarduzzi, G.6
Chiarugi, P.7
Camandola, S.8
Poli, G.9
Waeg, G.10
Gentilini, P.11
Dianzani, M.U.12
-
46
-
-
0033605582
-
Role of protein kinase C in the translational regulation of lipoprotein lipase in adipocytes
-
Ranganathan G, Kaakaji R, and Kern PA. Role of protein kinase C in the translational regulation of lipoprotein lipase in adipocytes. J Biol Chem 274: 9122-9127, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 9122-9127
-
-
Ranganathan, G.1
Kaakaji, R.2
Kern, P.A.3
-
47
-
-
0030463783
-
Expression and phorbol ester-induced down-regulation of protein kinase C isozymes in osteoblasts
-
Sanders JL and Stern PH. Expression and phorbol ester-induced down-regulation of protein kinase C isozymes in osteoblasts. J Bone Miner Res 11: 1862-1872, 1996.
-
(1996)
J Bone Miner Res
, vol.11
, pp. 1862-1872
-
-
Sanders, J.L.1
Stern, P.H.2
-
48
-
-
0037160092
-
Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression
-
Sasaki H, Sato H, Kuriyama-Matsumura K, Sato K, Maebara K, Wang H, Tamba M, Itoh K, Yamamoto M, and Bannai S. Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression. J Biol Chem 277: 44765-44771, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 44765-44771
-
-
Sasaki, H.1
Sato, H.2
Kuriyama-Matsumura, K.3
Sato, K.4
Maebara, K.5
Wang, H.6
Tamba, M.7
Itoh, K.8
Yamamoto, M.9
Bannai, S.10
-
49
-
-
0037015682
-
Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA 0132, the human homolog to INrf2
-
Sekhar KR, Yan XX, and Freeman ML. Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2. Oncogene 21: 6829-6834, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 6829-6834
-
-
Sekhar, K.R.1
Yan, X.X.2
Freeman, M.L.3
-
50
-
-
0035830320
-
Insulin and PIP3 activate PKC-ζ by mechanisms that are both dependent and independent of phosphorylation of activation loop (T410) and autophosphorylation (T560) sites
-
Standaert ML, Bandyopadhyay G, Kanoh Y, Sajan MP, and Farese RV. Insulin and PIP3 activate PKC-ζ by mechanisms that are both dependent and independent of phosphorylation of activation loop (T410) and autophosphorylation (T560) sites. Biochemistry 40: 249-255, 2001.
-
(2001)
Biochemistry
, vol.40
, pp. 249-255
-
-
Standaert, M.L.1
Bandyopadhyay, G.2
Kanoh, Y.3
Sajan, M.P.4
Farese, R.V.5
-
51
-
-
0030810216
-
Protein kinase C-ζ as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport
-
Standaert ML, Galloway L, Karnam P, Bandyopadhyay G, Moscat J, and Farese RV. Protein kinase C-ζ as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport. J Biol Chem 272: 30075-30082, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 30075-30082
-
-
Standaert, M.L.1
Galloway, L.2
Karnam, P.3
Bandyopadhyay, G.4
Moscat, J.5
Farese, R.V.6
-
52
-
-
0037462651
-
Degradation of transcription factor Nrf2 via the ubiquitin-proteosome pathway and stabilization by cadmium
-
Stewart D, Killeen E, Naquin R, Alam S, and Alam J. Degradation of transcription factor Nrf2 via the ubiquitin-proteosome pathway and stabilization by cadmium. J Biol Chem 278: 2396-2402, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 2396-2402
-
-
Stewart, D.1
Killeen, E.2
Naquin, R.3
Alam, S.4
Alam, J.5
-
53
-
-
0029906134
-
Nrf1 and Nrf2 positively and c-Fos and Fral negatively regulate the human antioxidant response element-mediated expression of NAD(P)H: Quinone oxidoreductase 1 gene
-
Venugopal R and Jaiswal AK. Nrf1 and Nrf2 positively and c-Fos and Fral negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene. Proc Natl Acad Sci USA 93: 14960-14965, 1996.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14960-14965
-
-
Venugopal, R.1
Jaiswal, A.K.2
-
54
-
-
0032542213
-
Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes
-
Venugopal R and Jaiswal AK. Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes. Oncogene 17: 3145-3156, 1998.
-
(1998)
Oncogene
, vol.17
, pp. 3145-3156
-
-
Venugopal, R.1
Jaiswal, A.K.2
-
55
-
-
0033584867
-
Regulation of γ-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf 2
-
Wild AC, Moinova HR, and Mulcahy RT. Regulation of γ-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2. J Biol Chem 274: 33627-33636, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 33627-33636
-
-
Wild, A.C.1
Moinova, H.R.2
Mulcahy, R.T.3
-
56
-
-
0027248964
-
Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C
-
Wilkinson SE, Parker PJ, and Nixon JS. Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. Biochem J 294: 335-337, 1993.
-
(1993)
Biochem J
, vol.294
, pp. 335-337
-
-
Wilkinson, S.E.1
Parker, P.J.2
Nixon, J.S.3
-
57
-
-
0034130117
-
Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: Relationship to differentiation and survival of PC12 cells
-
Wooten MW, Seibenhener ML, Neidigh KB, and Vandenplas ML. Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: relationship to differentiation and survival of PC12 cells. Mol Cell Biol 20: 4494-4504, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4494-4504
-
-
Wooten, M.W.1
Seibenhener, M.L.2
Neidigh, K.B.3
Vandenplas, M.L.4
-
58
-
-
0035193041
-
Nerve growth factor stimulates multisite tyrosine phosphorylation and activation of the atypical protein kinase C's via a src kinase pathway
-
Wooten MW, Vandenplas ML, Seibenhener ML, Geetha T, and Diaz-Meco MT. Nerve growth factor stimulates multisite tyrosine phosphorylation and activation of the atypical protein kinase C's via a src kinase pathway. Mol Cell Biol 21: 8414-8427, 2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8414-8427
-
-
Wooten, M.W.1
Vandenplas, M.L.2
Seibenhener, M.L.3
Geetha, T.4
Diaz-Meco, M.T.5
-
59
-
-
0023928278
-
Human heme oxygenase cDNA and induction of its mRNA by hemin
-
Yoshida T, Biro P, Cohen T, Muller RM, and Shibahara S. Human heme oxygenase cDNA and induction of its mRNA by hemin. Eur J Biochem 171: 457-461, 1988.
-
(1988)
Eur J Biochem
, vol.171
, pp. 457-461
-
-
Yoshida, T.1
Biro, P.2
Cohen, T.3
Muller, R.M.4
Shibahara, S.5
-
60
-
-
0037183998
-
The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm
-
Zipper LM and Mulcahy RT. The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm. J Biol Chem 277: 36544-36552, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 36544-36552
-
-
Zipper, L.M.1
Mulcahy, R.T.2
|