Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

Nature Cell Biology

Volumn 4, Issue 2, 2002, Pages 95-105

  Gervais, Francois G ^a   Singaraja, Roshni ^b   Xanthoudakis, Steven ^a   Gutekunst, Claire Ann ^c   Leavitt, Blair R ^b   Metzler, Martina ^b   Hackam, Abigail S ^b,d   Tam, John ^a   Vaillancourt, John P ^a   Houtzager, Vicky ^a   Rasper, Dita M ^a   Roy, Sophie ^a   Hayden, Michael R ^b   Nicholson, Donald W ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CASPASE 8; HUNTINGTIN; HUNTINGTIN INTERACTING PROTEIN 1; POLYGLUTAMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL LOSS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE ASSOCIATION; ENZYME ACTIVATION; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; MOUSE; NERVE CELL; NERVE DEGENERATION; NONHUMAN; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CARRIER PROTEINS; CASPASE 8; CASPASE 9; CASPASES; CELLS, CULTURED; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; HUNTINGTON DISEASE; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; PROTEIN STRUCTURE, TERTIARY; RATS; SEQUENCE ALIGNMENT; TISSUE DISTRIBUTION; TWO-HYBRID SYSTEM TECHNIQUES;

ANIMALIA;

EID: 0036173770     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb735     Document Type: Article

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