-
1
-
-
0029089172
-
When more is less: Pathogenesis of glutamine repeat neurodegenerative diseases
-
Ross, C.A. When more is less: Pathogenesis of glutamine repeat neurodegenerative diseases. Neuron 15, 493-496 (1995).
-
(1995)
Neuron
, vol.15
, pp. 493-496
-
-
Ross, C.A.1
-
2
-
-
0030294445
-
The expanding world of ataxins
-
Zoghbi, H.Y. The expanding world of ataxins. Nature Genet. 14, 237-239 (1996).
-
(1996)
Nature Genet.
, vol.14
, pp. 237-239
-
-
Zoghbi, H.Y.1
-
3
-
-
0004075694
-
-
Springer-Verlag, London, Berlin
-
Hayden, M.R. Huntington's chorea. 59-75, (Springer-Verlag, London, Berlin, 1981).
-
(1981)
Huntington's Chorea
, pp. 59-75
-
-
Hayden, M.R.1
-
5
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
Huntington's Disease Collaborative Research Group, A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72, 971-983 (1993).
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
6
-
-
0028316870
-
A worldwide study of the Huntington's disease mutation: The sensitivity and specificity of measuring CAG repeats
-
Kremer, H.P.H et al. A worldwide study of the Huntington's disease mutation: The sensitivity and specificity of measuring CAG repeats. New. Engl. J. Med. 330, 1401-1406 (1994).
-
(1994)
New. Engl. J. Med.
, vol.330
, pp. 1401-1406
-
-
Kremer, H.P.H.1
-
7
-
-
0027176364
-
The relationship between trinucleotide repeat (CAG) length and clinical features of Huntington disease
-
Andrew, S.E. et al. The relationship between trinucleotide repeat (CAG) length and clinical features of Huntington disease. Nature Genet. 4, 398-403 (1993).
-
(1993)
Nature Genet.
, vol.4
, pp. 398-403
-
-
Andrew, S.E.1
-
8
-
-
0027240431
-
Trinucleotide repeat length instability in Huntington disease
-
Duyao, M. et al. Trinucleotide repeat length instability in Huntington disease. Nature Genet. 4, 387-392 (1993).
-
(1993)
Nature Genet.
, vol.4
, pp. 387-392
-
-
Duyao, M.1
-
9
-
-
0027261537
-
Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease
-
Snell, R.G. et al. Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease. Nature Genet. 4, 393-397 (1993).
-
(1993)
Nature Genet.
, vol.4
, pp. 393-397
-
-
Snell, R.G.1
-
10
-
-
0027370252
-
Differential 3′ polyadenylation of the Huntington disease gene results in two mRNA species with variable tissue expression
-
Lin, B.-Y. et al. Differential 3′ polyadenylation of the Huntington disease gene results in two mRNA species with variable tissue expression. Hum. Mol. Genet. 2, 1541-1545 (1993).
-
(1993)
Hum. Mol. Genet.
, vol.2
, pp. 1541-1545
-
-
Lin, B.-Y.1
-
11
-
-
0029092340
-
Expression of the Huntington's disease (IT15) protein product in HD patients
-
Schilling, G. et al. Expression of the Huntington's disease (IT15) protein product in HD patients. Hum. Mol. Genet. 5, 1365-1371 (1995).
-
(1995)
Hum. Mol. Genet.
, vol.5
, pp. 1365-1371
-
-
Schilling, G.1
-
12
-
-
0029034511
-
Widespread expression of Huntington's disease gene (IT-15) protein product
-
Sharp, A. et al. Widespread expression of Huntington's disease gene (IT-15) protein product. Neuron 14, 1065-1074 (1995).
-
(1995)
Neuron
, vol.14
, pp. 1065-1074
-
-
Sharp, A.1
-
13
-
-
0028829596
-
CAG Expansion affects the expression of mutant huntingtin in the huntington's disease brain
-
Aronin, N. et al. CAG Expansion affects the expression of mutant huntingtin in the huntington's disease brain. Neuron 15, 1193-1201 (1995).
-
(1995)
Neuron
, vol.15
, pp. 1193-1201
-
-
Aronin, N.1
-
14
-
-
0022395922
-
Neuropathological classification of Huntington's disease
-
Vonsattel, J.P et al. Neuropathological classification of Huntington's disease. J. Neuropathol. Exp. Neurol. 44, 559-577 (1985).
-
(1985)
J. Neuropathol. Exp. Neurol.
, vol.44
, pp. 559-577
-
-
Vonsattel, J.P.1
-
15
-
-
0029014180
-
Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals
-
Servadio, A. et al. Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals. Nature Genet. 10, 94-98 (1995).
-
(1995)
Nature Genet.
, vol.10
, pp. 94-98
-
-
Servadio, A.1
-
16
-
-
0028989602
-
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
-
DiFiglia, M. et al. Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons. Neuron 14, 1075-1141 (1995).
-
(1995)
Neuron
, vol.14
, pp. 1075-1141
-
-
DiFiglia, M.1
-
17
-
-
0027381482
-
n repeat length is the sex of the affected parent
-
n repeat length is the sex of the affected parent. Hum. Mol. Genet. 2, 1535-1540 (1993).
-
(1993)
Hum. Mol. Genet.
, vol.2
, pp. 1535-1540
-
-
Telenius, H.1
-
18
-
-
0025940629
-
The two-hybrid system: A method to identify and clone genes for proteins that interact with a protein of interest
-
Chien, C.-T., Bartel, P.L., Sternglanz, R. & Fields, S. The two-hybrid system: A method to identify and clone genes for proteins that interact with a protein of interest. Proc. Natl. Acad. Sci. USA 88, 9578-9582 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 9578-9582
-
-
Chien, C.-T.1
Bartel, P.L.2
Sternglanz, R.3
Fields, S.4
-
19
-
-
0024406857
-
A novel genetic system to detect protein-protein interacts
-
Fields, S. & Song, O-K. A novel genetic system to detect protein-protein interacts. Nature 340, 245-246 (1993).
-
(1993)
Nature
, vol.340
, pp. 245-246
-
-
Fields, S.1
Song, O.-K.2
-
20
-
-
0027244817
-
Synthetic-lethal interactions identify two novel geries, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae
-
Holtzman, D.A., Yang, S. & Drubin, D.G. Synthetic-lethal interactions identify two novel geries, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae. J. Cell Biol. 122, 635-644 (1993).
-
(1993)
J. Cell Biol.
, vol.122
, pp. 635-644
-
-
Holtzman, D.A.1
Yang, S.2
Drubin, D.G.3
-
21
-
-
9444239187
-
Huntingtin is ubiquitinated and interacts with a specific ubiquitin conjugated enzyme
-
Kalchman, M.A. et al. Huntingtin is ubiquitinated and interacts with a specific ubiquitin conjugated enzyme. J. Biol. Chem. 271, 19385-19394 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19385-19394
-
-
Kalchman, M.A.1
-
22
-
-
0028803757
-
A huntingtin-associated protein enriched in brain with implications for pathology
-
Li, X.-J. et al. A huntingtin-associated protein enriched in brain with implications for pathology. Nature 378, 398-402 (1995).
-
(1995)
Nature
, vol.378
, pp. 398-402
-
-
Li, X.-J.1
-
24
-
-
0027455339
-
end3 and end4: Two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cervisiae
-
Raths, S., Rohrer, J., Crausaz, F. & Riezman, H. end3 and end4: Two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cervisiae. J. Cell Biol. 120, 55-65 (1993).
-
(1993)
J. Cell Biol.
, vol.120
, pp. 55-65
-
-
Raths, S.1
Rohrer, J.2
Crausaz, F.3
Riezman, H.4
-
25
-
-
0028077885
-
Troponin T is capable of binding dystrophin via a leucine zipper
-
Pearlman, J.A., Powaser, P.A., Elledge, S.J. & Caskey, C.T. Troponin T is capable of binding dystrophin via a leucine zipper. FEBS Letters 354, 183-186 (1994).
-
(1994)
FEBS Letters
, vol.354
, pp. 183-186
-
-
Pearlman, J.A.1
Powaser, P.A.2
Elledge, S.J.3
Caskey, C.T.4
-
26
-
-
0028362643
-
Two pairs of oppositely charged amino acids from Jun and Fos confer heterodimerization to GCN4 leucine zipper
-
John, M., Briand, J.P., Granger-Schnarr, M. & Schnarr, M. Two pairs of oppositely charged amino acids from Jun and Fos confer heterodimerization to GCN4 leucine zipper. J. Biol. Chem. 269, 16247-16253 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 16247-16253
-
-
John, M.1
Briand, J.P.2
Granger-Schnarr, M.3
Schnarr, M.4
-
27
-
-
0024990759
-
Sequence and domain structure of talin
-
Rees, D.J., Ades, S.E., Singer, S.J. & Hynes, R.O. Sequence and domain structure of talin. Nature 347, 18-63 (1990).
-
(1990)
Nature
, vol.347
, pp. 18-63
-
-
Rees, D.J.1
Ades, S.E.2
Singer, S.J.3
Hynes, R.O.4
-
28
-
-
0029055717
-
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes
-
Nasir, J. et al. Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes. Cell 81, 811-823 (1995).
-
(1995)
Cell
, vol.81
, pp. 811-823
-
-
Nasir, J.1
-
29
-
-
10544222019
-
Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype
-
Hodgson, J.G. et al. Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype. Hum. Mol. Genet. 5, 1875-1885 (1996).
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1875-1885
-
-
Hodgson, J.G.1
-
30
-
-
0028915976
-
Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: Studies in yeast and neural cells
-
Rabizadeh, S. et al. Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells. Proc. Natl. Acad. Sci. USA 92, 3024-3028 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3024-3028
-
-
Rabizadeh, S.1
-
31
-
-
0029150855
-
TEL1, an S. cerevisiae homologue of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1
-
Morrow, D.M., Tagle, D.A., Shiloh, Y., Collins, F.S. & Hieter, P. TEL1, an S. cerevisiae homologue of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell 82, 831-840 (1995).
-
(1995)
Cell
, vol.82
, pp. 831-840
-
-
Morrow, D.M.1
Tagle, D.A.2
Shiloh, Y.3
Collins, F.S.4
Hieter, P.5
-
32
-
-
0009482260
-
Electrophoretic transfer of proteins form polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
-
Towbin, H., Staehelin, T. & Gordon, J. Electrophoretic transfer of proteins form polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Natl. Acad. Sci. USA 76, 100-104 (1979).
-
(1979)
Proc. Natl. Acad. Sci. USA
, vol.76
, pp. 100-104
-
-
Towbin, H.1
Staehelin, T.2
Gordon, J.3
-
34
-
-
0023074953
-
Calcium ATPases: Contribution of molecular genetics to our understanding of structure and function
-
MacLennan, D.H., Brandl, C.J., Korczak, B. & Green, N.M. Calcium ATPases: contribution of molecular genetics to our understanding of structure and function. Soc. Gen. Phys. Ser. 41, 287-300 (1987).
-
(1987)
Soc. Gen. Phys. Ser.
, vol.41
, pp. 287-300
-
-
MacLennan, D.H.1
Brandl, C.J.2
Korczak, B.3
Green, N.M.4
-
35
-
-
0022558845
-
2+ ATPase genes: Homologies and mechanistic implications of deduced amino acid sequences
-
2+ ATPase genes: homologies and mechanistic implications of deduced amino acid sequences. Cell 44, 597-607 (1986).
-
(1986)
Cell
, vol.44
, pp. 597-607
-
-
Brandl, C.J.1
Green, N.M.2
Korczak, B.3
MacLennan, D.H.4
-
36
-
-
0345679151
-
Characteristics of cytosolic and membrane bound forms of huntingtin
-
Wood, J.D., Harper, P.S. & Jones, A.L. Characteristics of cytosolic and membrane bound forms of huntingtin. Am. J. Hum. Genet. 59, A295 (1996).
-
(1996)
Am. J. Hum. Genet.
, vol.59
-
-
Wood, J.D.1
Harper, P.S.2
Jones, A.L.3
-
37
-
-
0029947276
-
Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain
-
Wood, J.D., MacMillan, J.C., Harper, P.S., Lowenstein, P.R. & Jones, A.L. Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain. Hum. Mol. Genet. 5, 418-487 (1996).
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 418-487
-
-
Wood, J.D.1
MacMillan, J.C.2
Harper, P.S.3
Lowenstein, P.R.4
Jones, A.L.5
-
38
-
-
9444286388
-
Expression of normal and mutant huntingtin in the developing brain
-
Bhide P.G. et al. Expression of normal and mutant huntingtin in the developing brain. J. Neurosci. 16, 5523-5535 (1996).
-
(1996)
J. Neurosci.
, vol.16
, pp. 5523-5535
-
-
Bhide, P.G.1
-
39
-
-
0029664992
-
Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH
-
Burke, J.R. et al. Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH. Nature Med. 2, 347-350 (1996).
-
(1996)
Nature Med.
, vol.2
, pp. 347-350
-
-
Burke, J.R.1
-
40
-
-
0029691198
-
Emerging new functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells
-
Sirover, M.A. Emerging new functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells. Life Sci. 58, 2271-2277 (1996).
-
(1996)
Life Sci.
, vol.58
, pp. 2271-2277
-
-
Sirover, M.A.1
-
41
-
-
0029833062
-
Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase
-
Koshy, B. et al. Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase. Hum. Mol. Genet. 5, 1311-1318 (1996).
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1311-1318
-
-
Koshy, B.1
-
42
-
-
0029791355
-
Huntington disease: New insights into the relationship between CAG expansion and disease
-
Nasir, J., Goldberg, Y.P. & Hayden, M.R. Huntington disease: new insights into the relationship between CAG expansion and disease. Hum. Mol. Genet 5, 1431-1435 (1996).
-
(1996)
Hum. Mol. Genet
, vol.5
, pp. 1431-1435
-
-
Nasir, J.1
Goldberg, Y.P.2
Hayden, M.R.3
-
43
-
-
9344227302
-
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease is modulated by the polyglutamine tract
-
Goldberg, Y.P. et al. Cleavage of huntingtin by apopain, a proapoptotic cysteine protease is modulated by the polyglutamine tract. Nature Genet. 13, 442-449 (1996).
-
(1996)
Nature Genet.
, vol.13
, pp. 442-449
-
-
Goldberg, Y.P.1
-
44
-
-
9044229711
-
Absence of disease phenotype and intergenerational stability of the CAG repeat in transgenic mice expressing the human Huntington disease transcript
-
Goldberg, Y. et al. Absence of disease phenotype and intergenerational stability of the CAG repeat in transgenic mice expressing the human Huntington disease transcript. Hum. Mol. Genet. 5, 177-185 (1996).
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 177-185
-
-
Goldberg, Y.1
-
45
-
-
0027251721
-
The retinoblastoma protein associates with the protein phosphatase type 1 catalystic subunit
-
Durfee, T. et al. The retinoblastoma protein associates with the protein phosphatase type 1 catalystic subunit. Genes & Develop. 7, 555-569 (1993).
-
(1993)
Genes & Develop.
, vol.7
, pp. 555-569
-
-
Durfee, T.1
-
46
-
-
1842298317
-
Yeast growth and yeast transformation
-
eds Spector, D., Goldman, R. & Leinwand, L. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, In press
-
Gietz, R.D., Woods, R.A., Manivasakam, P. & Schiestl, R.H. Yeast growth and yeast transformation. in Cell Biology: A Laboratory Manual (eds Spector, D., Goldman, R. & Leinwand, L.) (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 1996). In press.
-
(1996)
Cell Biology: A Laboratory Manual
-
-
Gietz, R.D.1
Woods, R.A.2
Manivasakam, P.3
Schiestl, R.H.4
-
47
-
-
0029670218
-
Regional and cellular presenilin 1 gene expression in human and rat tissues
-
Suzuki, T. et al. Regional and cellular presenilin 1 gene expression in human and rat tissues. Biochem. Biophys. Res. Comm. 219, 708-713 (1996).
-
(1996)
Biochem. Biophys. Res. Comm.
, vol.219
, pp. 708-713
-
-
Suzuki, T.1
-
48
-
-
0027370252
-
Differential 3′ polyadenylation of the Huntington disease gene results in two mRNA species with variable tissue expression
-
Lin, B. et al. Differential 3′ polyadenylation of the Huntington disease gene results in two mRNA species with variable tissue expression. Hum. Mol. Genet. 2, 1541-1545 (1993).
-
(1993)
Hum. Mol. Genet.
, vol.2
, pp. 1541-1545
-
-
Lin, B.1
-
49
-
-
0028246621
-
Subcellular localization of the F5 protein to the neuronal membrane-associated cytoskeleton
-
Arai, M. & Cohen, J.A. Subcellular localization of the F5 protein to the neuronal membrane-associated cytoskeleton. J. Neurosc. Res. 38, 348-357 (1994).
-
(1994)
J. Neurosc. Res.
, vol.38
, pp. 348-357
-
-
Arai, M.1
Cohen, J.A.2
-
50
-
-
0031056478
-
HIP-1: A huntingtin interacting protein isolated by the yeast two-hybrid system
-
Wanker, E. et al. HIP-1: A huntingtin interacting protein isolated by the yeast two-hybrid system. Hum. Mol. Genet. 6, 487-495 (1997).
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 487-495
-
-
Wanker, E.1
|