Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl- 2

Journal of Cell Biology

Volumn 138, Issue 6, 1997, Pages 1219-1228

  He, Huiling ^a   Lam, Minh ^a   McCormick, Thomas S ^a   Distelhorst, Clark W ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN D; THAPSIGARGIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; ENDOPLASMIC RETICULUM; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; REGULATORY MECHANISM;

ANIMALS; APOPTOSIS; CALCIUM; CALCIUM-TRANSPORTING ATPASES; CELL DIVISION; CELL SURVIVAL; CYTOPLASM; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; HOMEOSTASIS; LYMPHOMA; MICE; PROTO-ONCOGENE PROTEINS C-BCL-2; THAPSIGARGIN; TIME FACTORS; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0030824575     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.138.6.1219     Document Type: Article

References (50)

1. Baffy, G., T. Miyashita, J.R. Williamson, and J.C. Reed. 1993. Apoplosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production. J. Biol. Chem. 268:6511-6519.
2. 2+ stores in induction and suppression of apoptosis in S49 cells. Am. J. Physiol. 272:C1241-C1249.
3. Booth, C., and G.L.E. Koch. 1989. Perturbation of cellular calcium induces secretion of luminal ER proteins. Cell. 59:729-737.
4. Brostrom, C.O., and M.A. Brostrom. 1990. Calcium-dependent regulation of protein synthesis in intact mammalian cells. Annu. Rev. Physiol. 52: 577-590.
5. Casciola-Rosen, L.A., G. Anhalt, and A. Rosen. 1994. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. J. Exp. Med. 179:1317-1330.
6. Chueh, S.-H., J.M. Mullaney, T.K. Ghosh, A.L. Zachary, and D.L. Gill. 1987. GTP- and inositol 1,4,5-trisphosphate-activated intracellular calcium movements in neuronal and smooth muscle cell lines. J. Biol. Chem. 262:13857-13864.
7. Clapham, D.E. 1995. Calcium signaling. Cell. 80:259-268.
8. Cory, S. 1995. Regulation of lymphocyte survival by the Bcl-2 gene family. Annu. Rev. Immunol. 13:513-543.
9. Deiss, L.P., H. Galinka, H. Berissi, O. Cohen, and A. Kimchi. 1996. Cathepsin D protease mediates programmed cell death induced by interferon-γ, Fas/APO-1 and TNF-α. EMBO (Eur. Mol. Biol. Organ.) J. 15:3861-3870.
10. Distelhorst, C.W., and T.S. McCormick. 1996. Bcl-2 acts subsequent to and independent of calcium fluxes to inhibit apoptosis in thapsigargin- and glucocorticoid-treated mouse lymphoma cells. Cell Calcium. 19:473-483.
11. 2+ pool depletion. Oncogene. 12:2051-2055.
12. Dowd, D.R., P.N. MacDonald, B.S. Komm, M.R. Haussler, and R.L. Miesfeld. 1992. Stable expression of the calbindin-D28K complementary DNA interferes with the apoptotic pathway in lymphocytes. Mol. Endocrinol. 6:1843-1848.
13. Faust, P.L., D.A. Wall, E. Perara, V.R. Lingappa, and S. Kornfeld. 1987. Expression of human cathepsin D in Xenopns oocytes: phosphorylation and intracellular targeting. J. Cell Biol. 105:1937-1945.
14. Furuya, Y., P. Lundmo, A.D. Short, D.L. Gill, and J.T. Isaacs. 1994. The role of calcium, pH, and cell proliferation in the programmed (apoptotic) death of androgen-independent prostatic cancer cells induced by thapsigargin. Cancer Res. 54:6167-6175.
15. Gething, M.-J., and J. Sambrook. 1992. Protein folding in the cell. Nature (Lond.). 355:33-45.
16. Hockenbery, D.M., Z.N. Oltvai, X.-M. Yin, C.L. Milliman, and S.J. Korsmeyer. 1993. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell. 75:241-251.
17. Jacobson, M.D., and M.C. Raff. 1995. Programmed cell death and Bcl-2 protection in very low oxygen. Nature (Lond.). 374:814-816.
18. 2+-ATPase inhibitor thapsigargin. Exp. Cell Res. 212:84-92.
19. Kane, D.J., T.A. Sarafian, R. Anton, H. Hahn, E.B. Gralla, J.S. Valentine, T. Örd, and D.E. Bredesen. 1993. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science (Wash. DC). 262: 1274-1277.
20. 2+ fluxes. Proc. Natl. Acad. Sci. USA. 91: 6569-6573.
21. Lam, M., L.J. Vimmerstedt, L.K. Schlatter, J.O. Hensold, and C.W. Distelhorst. 1992. Preferential synthesis of the 78-Kd glucose-regulated protein in glucocorticoid-treated S49 mouse lymphoma cells. Blood. 79:3285-3292.
22. 2+-ATPase inhibitor thapsigargin. J. Biol. Chem. 268:12003-12009.
23. Li, X., and A.S. Lee. 1991. Competitive inhibition of a set of endoplasmic reticulum protein genes (GRP78, GRP94, and ERp72) retards cell growth and lowers viability after ionophore treatment. Mol. Cell Biol. 11: 3446-3453.
24. Little, E., and A.S. Lee. 1995. Generation of a mammalian cell line deficient in glucose-regulated protein stress induction through targeted ribozyme driven by a stress-inducible promoter. J. Biol. Chem. 270:9526-9534.
25. Lodish, H.F., N. Kong, and L. Wikstrom. 1992. Calcium is required for folding of newly made subunits of the asialoglycoprotein receptor within the endoplasmic reticulum. J. Biol. Chem. 267:12753-12760.
26. London, E. 1992. Diptheria toxin: membrane interaction and membrane translocation. Biochim. Biophys. Acta. 1113:25-51.
27. Lytton, J., M. Westlin, and M.R. Hanley. 1991. Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. J. Biol. Chem. 266:17067-17071.
28. Magnelli, L., M. Cinelli, A. Turchetti, and V.P. Chiarugi. 1994. Bcl-2 over-expression abolishes early calcium waving preceding apoptosis in NIH-3T3 murine fibroblasts. Biochem. Biophys. Res. Commun. 204:84-90.
29. 2+. Oncogene. 12:2259-2266.
30. 45Ca autoradiography on nitrocellulose membrane after sodium dodecyl sulfate gel electrophoresis. J. Biochem. 95:511-519.
31. McCormick, T.S., K.S. McColl, and C.W. Distelhorst. 1997. Mouse lymphoma cells destined to undergo apoptosis in response to thapsigargin treatment fail to generate a calcium mediated grp78/grp94 stress response. J. Biol. Chem. 272:6087-6092.
32. Minn, A.J., P. Velez, S.L. Schendel, H. Liang, S.W. Muchmore, S.W. Fesik, M. Fill, and C.B. Thompson. 1997. Bcl-xL forms an ion channel in synthetic lipid membranes. Nature (Lond.). 385:353.
33. Muchmore, S.W., M. Sattler, H. Liang, R.P. Meadows, J.E. Harlan, H.S. Yoon, D. Nettesheim, B.S. Chang, C.B. Thompson, S.-L. Wong, S.-C. Ng, and S. W. Fesik. 1996. X-ray and NMR structure of human Bel-XL, an inhibitor of programmed cell death. Nature (Lond.). 381:335-341.
34. Murphy, A.N., D.E. Bredesen, G. Cortopassi, E. Wang, and G. Fiskum. 1996. Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. Proc. Natl. Acad. Sci. USA. 93:9893-9898.
35. Muschel, R.J., E.J. Bernhard, L. Garza, W.G. McKenna, and C.J. Koch. 1995. Induction of apoptosis at different oxygen tensions: evidence that oxygen radicals do not mediate apoptotic signaling. Cancer Res. 55:995-998.
36. Orrenius, S., M.J. Burkitt, G.E.N. Kass, J.M. Dypbukt, and P. Nicotera. 1992. Calcium ions and oxidative cell injury. Ann. Neurol. 32:S33-S42.
37. Peitsch, M.C., B. Polzar, H. Stephan, T. Crompton, H.R. MacDonald, H.G. Mannherz, and J. Tschopp. 1993. Characterization of the endogenous deoxyribonuclease involved in nuclear DNA degradation during apoptosis (programmed cell death). EMBO (Eur. Mol. Biol. Organ.) J. 12:371-377.
38. 2+ stores. Science (Wash. DC). 273:1875-1877.
39. Putney, J.W. 1990. Capacitative calcium entry revisited. Cell Calcium. 11: 611-624.
40. Putney, J.W., and G.S.J. Bird. 1993. The signal for capacitative calcium entry. Cell. 75:199-201.
41. Reynolds, J.E., and A. Eastman. 1996. Intracellular calcium stores are not required for Bcl-2-mediated protection from apoptosis. J. Biol. Chem. 271:27739-27743.
42. Sambrook, J.F. 1990. The involvement of calcium in transport of secretory proteins from the endoplasmic reticulum. Cell. 61:197-199.
43. Shimizu, S., Y. Eguchi, H. Kosaka, W. Kamiike, H. Matsuda, and Y. Tsujimoto. 1995. Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL. Nature (Lond.). 374:811-813.
44. 2+ pool content is linked to control of cell growth. Proc. Natl. Acad. Sci. USA. 90:4986-4990.
45. 2+-ATPase. Proc. Natl. Acad. Sci. USA. 87:2466-2470.
46. 2+ with Quin2. Methods Enzymol. 172:230-262.
47. Waldron, R.T., A.D. Short, and D.L. Gill. 1995. Thapsigargin-resistant intracellular calcium pumps: role in calcium pool function and growth of thapsigargin-resistant cells. J. Biol. Chem. 270:11955-11961.
48. Yang, E., and S.J. Korsmeyer. 1996. Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood. 88:386-401.
49. Zamzami, N., P. Marchetti, M. Castedo, D. Decaudin, A. Macho, T. Hirsch, S.A. Susin, P.X. Petit, B. Migotte, and G. Kroemer. 1995. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J. Exp. Med. 182: 367-377.
50. Zhu, W., A. Cowie, G.W. Wasfy, L.Z. Penn, B. Leber, and D.W. Andrews. 1996. Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types. EMBO (Eur. Mol. Biol. Organ.) J. 15:4130-4141.