T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis

Molecular and Cellular Biology

Volumn 17, Issue 6, 1997, Pages 3005-3012

  Jayaraman, Thottala ^a   Marks, Andrew R ^a  

^a The New York Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; DEXAMETHASONE; INOSITOL 1,4,5 TRISPHOSPHATE; T LYMPHOCYTE RECEPTOR;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; DIAGNOSIS; HUMAN; HUMAN CELL; IONIZING RADIATION; LEUKEMIA CELL LINE; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; RECEPTOR BINDING; T LYMPHOCYTE RECEPTOR GENE;

EID: 0030973158     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.6.3005     Document Type: Article

References (60)

1. Amasaki, Y., S. Kobayashi, T. Takeda, N. Ogura, S. Jodo, T. Nakabayashi, A. Tsutsumi, A. Fujisaku, and T. Koike. 1995. Up-regulated expression of Fas antigen (CD95) by peripheral naive and memory T cell subsets in patients with systemic lupus erythematosus (SLE): a possible mechanism for lymphopenia. Clin. Exp. Immunol. 99:245-250.
2. Bierer, B. E., S. L. Schreiber, and S. J. Burakoff. 1991. The effect of the immunosuppressant FK506 on alternate pathways of T cell activation. Eur. J. Immunol. 21:439-445.
3. Caelles, C., A. Helmberg, and M. Karin. 1994. p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 370: 220-223.
4. Cohen, J. J., and R. C. Duke. 1984. Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death. J. Immunol. 132:38-42.
5. Coligan, J. E., A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober (ed.). 1990. Current protocols in immunology, vol. 1. Wiley Interscience, New York, N.Y.
6. Debbas, M., and E. White. 1993. Wild-type p53 mediates apoptosis by E1QA, which is inhibited by E1B. Genes Dev. 7:546-554.
7. Duke, R. C., and J. J. Cohen. 1986. IL-2 addition: withdrawal of growth factor activates a suicide program in dependent T cells. Lymphokine Res. 5:289-299.
8. Dyson, N., K. Buchkovich, P. Whyte, and E. Harlow. 1989. The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus. Cell 58:249-255.
9. Dyson, N., P. M. Howley, K. Munger, and E. Harlow. 1989. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 243:934-937.
10. Evan G. I., A. H. Wyllie, C. S. Gilbert, T. D. Littlewood, H. Land, M. Brooks, C. M. Waters, L. Z. Penn, and D. C. Hancock. 1992. Induction of apoptosis in fibroblasts by c-myc protein. Cell 69:119-128.
11. Fanger, C. M., M. Hoth, G. R. Crabtree, and R. S. Lewis. 1995. Characterization of T cell mutants with defects in capacitative calcium entry: genetic evidence for physiological roles of CRAC channels. J. Biol. Chem. 131:655-667.
12. Griffith, T. S., T. Brunner, S. M. Fletcher, D. R. Green, and T. A. Ferguson. 1995. Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 270:1189-1192.
13. Groux H., D. Monte, B. Plouvier, A. Capron, and J.-C. Ameisen. 1993. CD3 mediated apoptosis of human medullary thymocytes and activated peripheral T cells: respective roles of interleukin-1, interleukin-2, interferon γ, and accessary cells. Eur. J. Immunol. 23:1623-1629.
14. Harnick, D. H., T. Jayaraman, L. Go, Y. Ma, P. Mulieri, and A. R. Marks. 1995. The human type 1 inositol 1,4,5-trisphosphate receptor from T lymphocytes: structure, localization and phosphorylation. J. Biol. Chem. 270: 2833-2840.
15. 2+ mobilization. Biochem. J. 247:695-700.
16. Jayaraman, T., and A. R. Marks. 1993. Rapamycin-FKBP12 blocks proliferation, induces differentiation, and inhibits cdc2 kinase activity in a myogenic cell line. J. Biol. Chem. 268:25385-25388.
17. Jayaraman, T., E. Ondriasova, K. Ondrias, D. Harnick, and A. R. Marks. 1995. The inositol 1,4,5-trisphosphate receptor is essential for T cell receptor signaling. Proc. Natl. Acad. Sci. USA 92:6007-6011.
18. 2+-ATPase inhibitor thapsigargin. Exp. Cell Res. 212:84-92.
19. Kaiser, N., and I. S. Edelman. 1977. Calcium dependence of glucocorticoid-induced lymphocytolysis. Proc. Natl. Acad. Sci. USA 74:638-642.
20. Kaiser, N., and I. S. Edelman. 1978. Further studies on the role of calcium in glucocorticoid-induced lymphocytolysis. Endocrinology 103:936-942.
21. Kao, J. P. Y., A. T. Harootunian, and R. Y. Tsien. 1989. Photochemically generated cytosolic calcium pulses and their detection by Fluo-3. J. Biol. Chem. 264:8179-8184.
22. Katsikis, P. D., E. S. Wunderlich, C. A. Smith, L. A. Herzenberg, and L. A. Herzenberg. 1995. Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J. Exp. Med. 181:2029-2036.
23. Khan, A. A., M. J. Soloski, A. H. Sharp, G. Schilling, D. M. Sabatini, S.-H. Li, C. A. Ross, and S. H. Snyder. 1996. Lymphocyte apoptosis: mediation by increased type 3 inositol 1,4,5-trisphosphate receptor. Science 273:503-507.
24. Klas, C., K. M. Debatin, R. R. Jonker, and P. H. Krammer. 1993. Activation interferes with the APO-1 pathway in mature T cells. Int. Immunol. 5:625-630.
25. Kuida, K., J. A. Lippke, G. Ku, M. W. Harding, D. J. Livingston, M. S. Su, and R. A. Flavell. 1995. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 267:2000-2003.
26. 2+ fluxes. Proc. Natl. Acad. Sci. USA 91: 6569-6573.
27. Lenardo, M. J. 1991. Interleukin 2 programs mouse T lymphocytes for apoptosis. Nature 353:858-861.
28. Li, P., H. Allen, S. Banerjee, S. Franklin, L. Herzog, C. Johnston, J. McDowell, M. Paskind, L. Rodman, and J. Salfeld. 1995. Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell 80:401-411.
29. Los, M., M. Van de Craen, L. C. Penning, H. Schenk, M. Westendorp, P. A. Baeuerle, W. Droge, P. H. Krammer, W. Fiers, and K. Schulze-Osthoff. 1995. Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature 375:81-83.
30. Lowe, S. W., E. M. Schmitt, S. W. Smith, B. A. Osborne, and T. Jacks. 1993. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362:847-849.
31. kip1. Mol. Cell. Biol. 16:6744-6751.
32. 2+ concentration. Arch. Biochem. Biophys. 269:365-370.
33. McConkey, D. J., P. Hartzell, J. F. Amador-Perez, S. Orrenius, and M. Jondal. 1989. Calcium-dependent killing of immature thymocytes by stimulation via the CD3/T cell receptor complex. J. Immunol. 143:1801-1806.
34. Nicolleti, I., G. Migliorati, M. C. Pagliacci, F. Grignani, and C. Riccardi. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods 139: 271-279.
35. Nieto, M. A., and A. Lopez-Rivas. 1989. IL2 protects T lymphocytes from glucocorticoid induced DNA fragmentation and cell death. J. Immunol. 143:4166-4170.
36. Owen-Schaub, L. B., S. Yonehara, W. L. Crump, and E. Grimm. 1992. DNA fragmentation and cell death is selectively triggered in activated human T lymphocytes by fas antigen engagement. Cell. Immunol. 140:197-205.
37. Perandones, C. E., V. A. Illera, D. Peckham, L. L. Stunz, and R. F. Ashman. 1993. Regulation of apoptosis in vitro in mature murine spleen T cells. J. Immunol. 151:3521-3529.
38. Putney, J. W. 1986. A model for receptor-regulated calcium entry. Cell Calcium 7:1-12.
39. Putney, J. W., and G. S. J. Bird. 1993. The signal for capacitative calcium entry. Cell 75:199-201.
40. Qin, X., D. Livingston, W. Kaelin, and P. Adams. 1994. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA 91:10918-10922.
41. Rodriguez-Tarduchy, G., P. Malde, A. Lopez-Rivas, and M. Collins. 1992. Inhibition of apoptosis by calcium ionophores in IL-3-dependent bone marrow cells is dependent on production of IL-4. J. Immunol. 148:1416-1422.
42. Russal, J. H., C. L. White, D. Y. Loh, and P. Meleedy-Rey. 1991. Receptor stimulated death pathway is opened by antigen in mature T cells. Proc. Natl. Acad. Sci. USA 88:2151-2155.
43. Sellins, K. S., and J. J. Cohen. 1987. Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes. J. Immunol. 139:3199-3206.
44. Shan, B., and W. H. Lee. 1994. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell. Biol. 14:8166-8173.
45. Shi, Y., R. P. Bissonnette, N. Parfrey, M. Szaley, R. T. Kubo, and D. R. Green. 1991. In vivo administration of monoclonal antibodies to the CD3 T cell receptor complex induces cell death in immature thymocytes. J. Immunol. 146:3340-3346.
46. Smith, C. A., G. T. Williams, R. Kingston, E. J. Jenkininson, and J. J. Owen. 1989. Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures. Nature 337:181-184.
47. Story, M. D., L. C. Stephens, S. P. Tomasovic, and R. E. Meyn. 1992. A role for calcium in regulating apoptosis in rat thymocytes irradiated in vitro. Int. J. Radiat. Biol. 61:243-251.
48. Takahashi, S., H. T. Maecker, and R. Levy. 1989. DNA fragmentation and cell death mediated by T cell antigen receptor/CD3 complex on a leukemia T cell line. Eur. J. Immunol. 19:1911-1919.
49. Trauth, B. C, C. Klas, A. M. J. Peters, S. Matzku, P. Moller, W. Falk, K.-M. Debatin, and P. Krammer. 1989. Monoclonal antibody-mediated tumor regression by inducers of apoptosis. Science 245:301-305.
50. Tsuda, H., R. W. Huang, and K. Takatsuki. 1993. Interleukin 2 prevents programmed cell death in adult T cell leukemia cells. Jpn. J. Cancer Res. 84:431-437.
51. Tucek-Szabo, C. L., S. Andjelic, E. Lacy, K. B. Elkon, and J. Nikolic-Zugic. 1996 Surface T cell Fas receptor/CD95 regulation, in vivo activation, and apoptosis. Activation-induced death can occur without Fas receptor. J. Immunol. 156:192-200.
52. 2+-binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science 271:521-525.
53. Weiss, A., and D. R. Littman. 1994. Signal transduction by lymphocyte antigen receptors. Cell 76:263-274.
54. Wojcikiewicz, R. J. H. 1995. Type I, II, and III inositol 1,4,5-trisphosphate receptors are equally susceptible to down-regulation and are expressed in markedly different proportions in different cell types. J. Biol. Chem. 270: 11678-11683.
55. Wu, X., and A. J. Levine. 1994. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA 91:3602-3606.
56. Wyllie, A. H. 1980. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284:555-556.
57. Yamamoto-Hino, M., T. Sugiyama, K. Hikichi, M. Mattel, K. Hasegawa, S. Sekine, K. Sakurada, A. Miyakawa, T. Furuichi, M. Hasegawa, and K. Mikoshiba. 1994. Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors. Recept. Channels 2:9-22.
58. Yonehara, S., A. Ishii, and M. Yonehara. 1989. A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-down regulated with the receptor of tumor necrosis factor. J. Exp. Med. 169:1747-1756.
59. Zauli, G., D. Gibellini, A. Caputo, A. Bassini, M. Negrini, M. Monne, M. Mazzoni, and S. Capitani. 1995. The human immunodeficiency virus type-1 Tat protein upregulates Bcl-2 gene expression in Jurkat T-cell lines and primary peripheral blood mononuclear cells. Blood 86:3823-3834.
60. 2+ entry. Cell 85:661-671.