Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis

Journal of Cell Biology

Volumn 150, Issue 4, 2000, Pages 731-740

  Nakamura, Kimitoshi ^a   Bossy Wetzel, Ella ^b   Burns, Kimberly ^a   Fadel, Marc P ^c   Lozyk, Mira ^c   Goping, Ing Swie ^a   Opas, Michal ^c   Chris Bleackley, R ^a   Green, Douglas R ^b   Michalak, Marek ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Apoptosis; Calcium binding protein; Calreticulin; Endoplasmic reticulum

Indexed keywords

CALCIUM; CALNEXIN; CALRETICULIN; CASPASE 3; CYTOCHROME C OXIDASE; MEMBRANE PROTEIN; STAUROSPORINE; THAPSIGARGIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CHEMOSENSITIVITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME RELEASE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; CALCIUM; CALCIUM-BINDING PROTEINS; CALNEXIN; CALRETICULIN; CELL LINE; CLONING, MOLECULAR; CYTOCHROME C GROUP; DOGS; ENDOPLASMIC RETICULUM; ETOPOSIDE; HELA CELLS; HUMANS; MEMBRANE PROTEINS; MICE; MITOCHONDRIA; MOLECULAR CHAPERONES; RABBITS; RIBONUCLEOPROTEINS; STAUROSPORINE; T-LYMPHOCYTES; THAPSIGARGIN; ULTRAVIOLET RAYS;

ANIMALIA;

EID: 0034698838     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.150.4.731     Document Type: Article

References (66)

1. Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production
2. Cell death and control of cell survival in the oligodendrocyte lineage
3. 2+ stores and reveals aspects of their luminal microenvironment and function
4. Calnexin: A membrane-bound chaperone of the endoplasmic reticulum
5. Induction of a common pathway of apoptosis by staurosporine
6. Caspases induce cytochrome c release from mitochondria by activating cytosolic factors
7. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
8. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
9. 2+ waves
10. The three transforming regions of SV40 T antigen are required for immortalization of primary mouse embryo fibroblasts
11. Calreticulin is essential for integrin-mediated calcium signalling and cell adhesion
12. 2- pool depletion
13. Delayed activation of the store-operated calcium current induced by calreticulin overexpression in RBL-I cells
14. 2+ concentration within the endoplasmic reticulum
15. Role of TGF beta s and BMPs as signals controlling the position of the digits and the areas of interdigital cell death in the developing chick limb autopod
16. Quality control in the secretory pathway
17. Calnexin, calreticulin and the folding of glycoproteins
18. Inositol 1,4,5-trisphosphate receptor type 1 is a substrate for caspase-3 and is cleaved during apoptosis in a caspase-3-dependent manner
19. Calnexin discriminates between protein conformational states and functions as a molecular chaperone in vitro
20. Programmed cell death and Bcl-2 protection in the absence of a nucleus
21. Programmed cell death and animal development
22. T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis
23. Differential modulation of SERCA2 isoforms by calreticulin
24. Calreticulin
25. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
26. Effect of glucocorticosteroid treatment on intracellular calcium homeostasis in mouse lymphoma cells
27. 2+ fluxes
28. The protein product of the oncogene bcl-2 is a component of the nuclear envelope, the endoplasmic reticulum, and the outer mitochondrial membrane
29. 2+ response to bradykinin and increases sensitivity to ionomycin in NG-108-15 cells
30. 2+ store and inhibition of N-linked glycosylation
31. 2+
32. Apoptosis - Molecular mechanisms and biomedical implications
33. 2+ store: A view from the lumen
34. 2+ influx
35. Calreticulin is essential for cardiac development
36. Endoplasmic reticulum form of calreticulin modulates glucocorticoid-sensitive gene expression
37. Calreticulin: One protein, one gene, many functions
38. Calreticulin, and not calsequestrin, is the major calcium binding protein of smooth muscle sarcoplasmic reticulum and liver endoplasmic reticulum
39. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
40. Apoptosis by death factor
41. Excess copper and ceruloplasmin biosynthesis in long-term cultured hepatocytes from Long-Evans Cinnamon (LEC) rats, a model of Wilson disease
42. Bc1-XL cooperatively associates with the Bap31 complex in the endoplasmic reticulum, dependent on procaspase-8 and Ced-4 adaptor
43. p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum
44. Calreticulin is transcriptionally upregulated by heat shock, calcium and heavy metals
45. Regulation of expression and intracellular distribution of calreticulin, a major calcium binding protein of nonmuscle cells
46. Cell death during development of the nervous system
47. 2+ influx in Bcl-2-overexpressing cells
48. Molecular and cellular physiology of intracellular calcium stores
49. An intracellular calcium store regulates protein synthesis in HeLa cells, but it is not the hormone-sensitive store
50. Programmed cell death and the control of cell survival: Lessons from the nervous system
51. Intracellular calcium stores are not required for Bcl-2-mediated protection from apoptosis
52. 2+ responses
53. Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins
54. Definition of the lectin-like properties of the molecular chaperone, calreticulin, and demonstration of its copurification with endomannosidase from rat liver Golgi
55. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
56. 3-linked mitochondrial calcium signals
57. 2+-ATPase
58. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
59. Oligosaccharide binding characteristics of the molecular chaperones calnexin and calreticulin
60. Regulation of calreticulin gene expression by calcium
61. BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases
62. Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis
63. Enhanced catalysis of ribonuclease B folding by the interaction of calnexin or calreticulin with ERp57
64. Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types
65. Requirement for BMP signaling in interdigital apoptosis and scale formation