Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

Nature Cell Biology

Volumn 1, Issue 8, 1999, Pages 479-485

  Katayama, Taiichi ^a,b,c   Imaizumi, Kazunori ^a,b,c   Sato, Naoya ^a,b,c   Miyoshi, Ko ^a,c   Kudo, Takashi ^a   Hitomi, Junichi ^a,c   Morihara, Takashi ^a,c   Yoneda, Takunari ^a,c   Gomi, Fumi ^a,c   Mori, Yasutake ^a,c   Nakano, Yuka ^a   Takeda, Junji ^a   Tsuda, Takehide ^d   Itoyama, Yasuto ^d   Murayama, Ohoshi ^e   Takashima, Akihiko ^e   St George Hyslop, Peter ^f   Takeda, Masatoshi ^a   Tohyama, Masaya ^a,c  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^f UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIMYCIN; CARRIER PROTEIN; CHAPERONE; ERN2 PROTEIN, HUMAN; ERN2 PROTEIN, MOUSE; GLUCOSE REGULATED PROTEINS; GLUCOSE-REGULATED PROTEINS; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; MEMBRANE PROTEIN; MESSENGER RNA; MOLECULAR CHAPERONE GRP78; PRESENILIN 1; PROTEIN SERINE THREONINE KINASE; PSEN1 PROTEIN, HUMAN; RIBONUCLEASE; TUNICAMYCIN;

ALZHEIMER DISEASE; ANIMAL; ARTICLE; BRAIN; CELL DEATH; CELL LINE; DRUG EFFECT; ENDOPLASMIC RETICULUM; GENETIC TRANSFECTION; GENETICS; HUMAN; INTRACELLULAR MEMBRANE; METABOLISM; MOUSE; MUTATION; NERVE CELL; NEUROBLASTOMA; PATHOLOGY; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN FOLDING; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; ANIMALS; BRAIN; CALCIMYCIN; CARRIER PROTEINS; CELL DEATH; CELL LINE; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INTRACELLULAR MEMBRANES; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MOLECULAR CHAPERONES; MUTATION; NEUROBLASTOMA; NEURONS; PHOSPHORYLATION; PRESENILIN-1; PROTEIN BINDING; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION; TUNICAMYCIN;

EID: 0033258544     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/70265     Document Type: Article

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