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Volumn 57, Issue 2, 2005, Pages 217-252

Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors

Author keywords

[No Author keywords available]

Indexed keywords

4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; 5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; 5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; 6 (2,4 DIFLUOROPHENYLTHIO) 5 METHANESULFONAMIDO 1 INDANONE; ACETYLSALICYLIC ACID; ARL 17477; BICUCULLINE; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; CYCLOSPORIN A; ETODOLAC; GW 273629; INDOMETACIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MELOXICAM; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NIMESULIDE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; ROFECOXIB; S 2474; S [2 (1 IMINOETHYLAMINO)ETHYL]HOMOCYSTEINE; SULINDAC; TACROLIMUS; TILMACOXIB; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALERYL SALICYLATE;

EID: 22944434894     PISSN: 00316997     EISSN: None     Source Type: Journal    
DOI: 10.1124/pr.57.2.1     Document Type: Review
Times cited : (319)

References (466)
  • 1
    • 0035656866 scopus 로고    scopus 로고
    • NO and inflammatory mediators in the perpetuation of osteoarthritis
    • Abramson SB, Attur M, Amin AR, and Clancy R (2001) NO and inflammatory mediators in the perpetuation of osteoarthritis. Curr Rheumatol Rep 3:535-541.
    • (2001) Curr Rheumatol Rep , vol.3 , pp. 535-541
    • Abramson, S.B.1    Attur, M.2    Amin, A.R.3    Clancy, R.4
  • 3
    • 0024440973 scopus 로고
    • L-Arginine availability determines the duration of acetylcholine-induced systemic vasodilation in vivo
    • Aisaka K, Gross SS, Griffith OW, and Levi R (1989) L-Arginine availability determines the duration of acetylcholine-induced systemic vasodilation in vivo. Biochem Biophys Res Commun 163:710-717.
    • (1989) Biochem Biophys Res Commun , vol.163 , pp. 710-717
    • Aisaka, K.1    Gross, S.S.2    Griffith, O.W.3    Levi, R.4
  • 4
    • 33444456484 scopus 로고    scopus 로고
    • GW274150 is a potent, long acting, highly selective inhibitor of inducible NO synthase (NOS-2) with therapeutic potential in post-operative ileus
    • Portland Press, London
    • Alderton W, Angell A, Clayton N, Craig C, Dawson J, Frend A, McGill J, Moncada S, and Rees D (2000) GW274150 is a potent, long acting, highly selective inhibitor of inducible NO synthase (NOS-2) with therapeutic potential in post-operative ileus, in Biology of Nitric Oxide, pp 25-34, vol 7, Portland Press, London.
    • (2000) Biology of Nitric Oxide , vol.7 , pp. 25-34
    • Alderton, W.1    Angell, A.2    Clayton, N.3    Craig, C.4    Dawson, J.5    Frend, A.6    McGill, J.7    Moncada, S.8    Rees, D.9
  • 5
    • 0035425503 scopus 로고    scopus 로고
    • NO synthases: Structure, function and inhibition
    • Alderton WK, Cooper CE, and Knowles RG (2001) NO synthases: structure, function and inhibition. Biochem J 357:593-615.
    • (2001) Biochem J , vol.357 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 7
    • 0033534725 scopus 로고    scopus 로고
    • Kinetics of peroxynitrite reaction with amino acids and human serum albumin
    • Alvarez B, Ferrer-Sueta G, Freeman BA, and Radi R (1999) Kinetics of peroxynitrite reaction with amino acids and human serum albumin. J Biol Chem 274:842-848.
    • (1999) J Biol Chem , vol.274 , pp. 842-848
    • Alvarez, B.1    Ferrer-Sueta, G.2    Freeman, B.A.3    Radi, R.4
  • 9
    • 0029888972 scopus 로고    scopus 로고
    • Selective inhibition of COX (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis
    • Anderson GD, Hauser SD, McGarity KL, Bremer ME, Isakson PC, and Gregory SA (1996) Selective inhibition of COX (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis. J Clin Investig 97:2672-2679.
    • (1996) J Clin Investig , vol.97 , pp. 2672-2679
    • Anderson, G.D.1    Hauser, S.D.2    McGarity, K.L.3    Bremer, M.E.4    Isakson, P.C.5    Gregory, S.A.6
  • 10
    • 0035887744 scopus 로고    scopus 로고
    • Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice
    • Andreasson KI, Savonenko A, Vidensky S, Goellner JJ, and Zhang Y (2001) Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice. J Neurosci 21:8198-8209.
    • (2001) J Neurosci , vol.21 , pp. 8198-8209
    • Andreasson, K.I.1    Savonenko, A.2    Vidensky, S.3    Goellner, J.J.4    Zhang, Y.5
  • 11
    • 0025762709 scopus 로고
    • Endogenous nitrates-implications for treatment and prevention
    • Anggard EE (1991) Endogenous nitrates-implications for treatment and prevention. Eur Heart J 12 (Suppl A):5-8.
    • (1991) Eur Heart J , vol.12 , Issue.SUPPL. A , pp. 5-8
    • Anggard, E.E.1
  • 12
    • 0034799564 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitor NS-398 protects neuronal cultures from lipopolysaccharide-induced neurotoxicity
    • Araki E, Forster C, Dubinsky JM, Ross ME, and Iadecola C (2001) Cyclooxygenase-2 inhibitor NS-398 protects neuronal cultures from lipopolysaccharide-induced neurotoxicity. Stroke 32:2370-2375.
    • (2001) Stroke , vol.32 , pp. 2370-2375
    • Araki, E.1    Forster, C.2    Dubinsky, J.M.3    Ross, M.E.4    Iadecola, C.5
  • 13
    • 0023217399 scopus 로고
    • Non-steroidal anti-inflammatory drugs and life threatening complications of peptic ulceration
    • Armstrong CP and Blower AL (1987) Non-steroidal anti-inflammatory drugs and life threatening complications of peptic ulceration. Gut 28:527-532.
    • (1987) Gut , vol.28 , pp. 527-532
    • Armstrong, C.P.1    Blower, A.L.2
  • 14
    • 0027434610 scopus 로고
    • Anti-nociceptive activity of nitric oxide synthase inhibitors in the mouse: Dissociation between the effect of L-NAME and L-NMMA
    • Babbedge RC, Hart SL, and Moore PK (1993) Anti-nociceptive activity of nitric oxide synthase inhibitors in the mouse: dissociation between the effect of L-NAME and L-NMMA. J Pharm Pharmacol 45:77-79.
    • (1993) J Pharm Pharmacol , vol.45 , pp. 77-79
    • Babbedge, R.C.1    Hart, S.L.2    Moore, P.K.3
  • 15
    • 0032502351 scopus 로고    scopus 로고
    • N5-(1-Imino-3-butenyl)-L-ornithine. A neuronal isoform selective mechanism-based inactivator of NO synthase
    • Babu BR and Griffith OW (1998a) N5-(1-Imino-3-butenyl)-L-ornithine. A neuronal isoform selective mechanism-based inactivator of NO synthase. J Biol Chem 273:8882-8889.
    • (1998) J Biol Chem , vol.273 , pp. 8882-8889
    • Babu, B.R.1    Griffith, O.W.2
  • 16
    • 0032133353 scopus 로고    scopus 로고
    • Design of isoform-selective inhibitors of NO synthase
    • Babu BR and Griffith OW (1998b) Design of isoform-selective inhibitors of NO synthase. Curr Opin Chem Biol 2:491-500.
    • (1998) Curr Opin Chem Biol , vol.2 , pp. 491-500
    • Babu, B.R.1    Griffith, O.W.2
  • 17
    • 0034905269 scopus 로고    scopus 로고
    • Expression of COX-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398
    • Bae SH, Jung ES, Park YM, Kim BS, Kim BK, Kim DG, and Ryu WS (2001) Expression of COX-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398. Clin Cancer Res 7:1410-1418.
    • (2001) Clin Cancer Res , vol.7 , pp. 1410-1418
    • Bae, S.H.1    Jung, E.S.2    Park, Y.M.3    Kim, B.S.4    Kim, B.K.5    Kim, D.G.6    Ryu, W.S.7
  • 19
    • 0021981376 scopus 로고
    • Restoration of prostacyclin synthase in vascular smooth muscle cells after aspirin treatment: Regulation by epidermal growth factor
    • Bailey JM, Muza B, Hla T, and Salata K (1985) Restoration of prostacyclin synthase in vascular smooth muscle cells after aspirin treatment: regulation by epidermal growth factor. J Lipid Res 26:54-61.
    • (1985) J Lipid Res , vol.26 , pp. 54-61
    • Bailey, J.M.1    Muza, B.2    Hla, T.3    Salata, K.4
  • 22
    • 0026667091 scopus 로고
    • Chronic blockade of NO synthesis in the rat produces systemic hypertension and glomerular damage
    • Baylis C, Mitruka B, and Deng A (1992) Chronic blockade of NO synthesis in the rat produces systemic hypertension and glomerular damage. J Clin Investig 90:278-281.
    • (1992) J Clin Investig , vol.90 , pp. 278-281
    • Baylis, C.1    Mitruka, B.2    Deng, A.3
  • 23
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from NO and superoxide
    • Beckman JS, Beckman TW, Chen J, Marshall PA, and Freeman BA (1990) Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from NO and superoxide. Proc Natl Acad Sci USA 87:1620-1624.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 24
    • 0029805172 scopus 로고    scopus 로고
    • NO, superoxide, and peroxynitrite: The good, the bad and ugly
    • Beckman JS and Koppenol WH (1996) NO, superoxide, and peroxynitrite: the good, the bad and ugly. Am J Physiol 271:C1424-C1437.
    • (1996) Am J Physiol , vol.271
    • Beckman, J.S.1    Koppenol, W.H.2
  • 25
    • 0032516793 scopus 로고    scopus 로고
    • Localization of cyclooxygenase-2 and prostaglandin E2 receptor EP3 in the rat lumbar spinal cord
    • Beiche F, Klein T, Nusing R, Neuhuber W, and Goppelt-Struebe M (1998) Localization of cyclooxygenase-2 and prostaglandin E2 receptor EP3 in the rat lumbar spinal cord. J Neuroimmunol 89:26-34.
    • (1998) J Neuroimmunol , vol.89 , pp. 26-34
    • Beiche, F.1    Klein, T.2    Nusing, R.3    Neuhuber, W.4    Goppelt-Struebe, M.5
  • 26
    • 0030597962 scopus 로고    scopus 로고
    • Up-regulation of COX-2 mRNA in the rat spinal cord following peripheral inflammation
    • Beiche F, Scheuerer S, Brune K, Geisslinger G, and Goppelt-Struebe M (1996) Up-regulation of COX-2 mRNA in the rat spinal cord following peripheral inflammation. FEBS Lett 390:165-169.
    • (1996) FEBS Lett , vol.390 , pp. 165-169
    • Beiche, F.1    Scheuerer, S.2    Brune, K.3    Geisslinger, G.4    Goppelt-Struebe, M.5
  • 27
    • 0036082632 scopus 로고    scopus 로고
    • COX-2 products compensate for inhibition of NO regulation of renal perfusion
    • Beierwaltes WH (2002) COX-2 products compensate for inhibition of NO regulation of renal perfusion. Am J Physiol Renal Physiol 283:F68-F72.
    • (2002) Am J Physiol Renal Physiol , vol.283
    • Beierwaltes, W.H.1
  • 28
    • 0025726362 scopus 로고
    • Human vascular smooth muscle cells inhibit platelet aggregation when incubated with glyceryl trinitrate: Evidence for generation of nitric oxide
    • Benjamin N, Dutton JAE, and Ritter JM (1991) Human vascular smooth muscle cells inhibit platelet aggregation when incubated with glyceryl trinitrate: evidence for generation of nitric oxide. Br J Pharmacol 102:847-850.
    • (1991) Br J Pharmacol , vol.102 , pp. 847-850
    • Benjamin, N.1    Dutton, J.A.E.2    Ritter, J.M.3
  • 29
    • 85047677246 scopus 로고
    • Importance of basal NO synthesis in regulation of myocardial blood flow
    • Benyo Z, Kiss G, Szabo C, Csaki C, and Kovach AG (1991) Importance of basal NO synthesis in regulation of myocardial blood flow. Cardiovasc Res 25:700-703.
    • (1991) Cardiovasc Res , vol.25 , pp. 700-703
    • Benyo, Z.1    Kiss, G.2    Szabo, C.3    Csaki, C.4    Kovach, A.G.5
  • 30
  • 33
    • 0028227750 scopus 로고
    • Vasoreactivity of the culprit lesion in unstable angina
    • Bogaty P, Hackett D, Davies G, and Maseri A (1994) Vasoreactivity of the culprit lesion in unstable angina. Circulation 90:5-11.
    • (1994) Circulation , vol.90 , pp. 5-11
    • Bogaty, P.1    Hackett, D.2    Davies, G.3    Maseri, A.4
  • 34
    • 0026576899 scopus 로고
    • Identification of inhibitors of NO synthase that do not interact with the endothelial cell L-arginine transporter
    • Bogle RG, Moncada S, Pearson JD, and Mann GE (1992) Identification of inhibitors of NO synthase that do not interact with the endothelial cell L-arginine transporter. Br J Pharmacol 105:768-770.
    • (1992) Br J Pharmacol , vol.105 , pp. 768-770
    • Bogle, R.G.1    Moncada, S.2    Pearson, J.D.3    Mann, G.E.4
  • 35
    • 0026702955 scopus 로고
    • Microglial-produced NO and reactive nitrogen oxides mediate neuronal cell death
    • Boje KM and Arora PK (1992) Microglial-produced NO and reactive nitrogen oxides mediate neuronal cell death. Brain Res 587:250-256.
    • (1992) Brain Res , vol.587 , pp. 250-256
    • Boje, K.M.1    Arora, P.K.2
  • 36
    • 0030793528 scopus 로고    scopus 로고
    • Activation of nuclear factor-kappa B by beta-amyloid peptides and interferon-gamma in murine microglia
    • Bonaiuto C, McDonald PP, Rossi F, and Cassatella MA (1997) Activation of nuclear factor-kappa B by beta-amyloid peptides and interferon-gamma in murine microglia. J Neuroimmunol 77:51-56.
    • (1997) J Neuroimmunol , vol.77 , pp. 51-56
    • Bonaiuto, C.1    McDonald, P.P.2    Rossi, F.3    Cassatella, M.A.4
  • 39
    • 0028902109 scopus 로고
    • Characterization of inducible cyclooxygenase in rat brain
    • Breder CD, DeWitt D, and Kraig RP (1995) Characterization of inducible cyclooxygenase in rat brain. J Comp Neurol 355:296-315.
    • (1995) J Comp Neurol , vol.355 , pp. 296-315
    • Breder, C.D.1    DeWitt, D.2    Kraig, R.P.3
  • 40
    • 0025941639 scopus 로고
    • NO synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase
    • Bredt DS, Glatt CE, Hwang PM, Fotuhi M, Dawson TM, and Snyder SH (1991) NO synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase. Neuron 7:615-624.
    • (1991) Neuron , vol.7 , pp. 615-624
    • Bredt, D.S.1    Glatt, C.E.2    Hwang, P.M.3    Fotuhi, M.4    Dawson, T.M.5    Snyder, S.H.6
  • 41
    • 0025011298 scopus 로고
    • Localization of NO synthase indicating a neural role for NO
    • Bredt DS, Hwang PM, and Snyder SH (1990) Localization of NO synthase indicating a neural role for NO. Nature (Lond) 347:768-770.
    • (1990) Nature (Lond) , vol.347 , pp. 768-770
    • Bredt, D.S.1    Hwang, P.M.2    Snyder, S.H.3
  • 42
    • 0032877782 scopus 로고    scopus 로고
    • Pharmacological modulation of NO synthesis by mechanism-based inactivators and related inhibitors
    • Bryk R and Wolff DJ (1999) Pharmacological modulation of NO synthesis by mechanism-based inactivators and related inhibitors. Pharmacol Ther 84:157-178.
    • (1999) Pharmacol Ther , vol.84 , pp. 157-178
    • Bryk, R.1    Wolff, D.J.2
  • 45
    • 0041302369 scopus 로고    scopus 로고
    • Assessment of the relative contribution of COX-1 and COX-2 isoforms to ischemia-induced oxidative damage and neurodegeneration following transient global cerebral ischemia
    • Candelario-Jalil E, Gonzalez-Falcon A, Garcia-Cabrera M, Alvarez D, Al-Dalain S, Martinez G, Leon OS, and Springer JE (2003) Assessment of the relative contribution of COX-1 and COX-2 isoforms to ischemia-induced oxidative damage and neurodegeneration following transient global cerebral ischemia. J Neurochem 86:545-555.
    • (2003) J Neurochem , vol.86 , pp. 545-555
    • Candelario-Jalil, E.1    Gonzalez-Falcon, A.2    Garcia-Cabrera, M.3    Alvarez, D.4    Al-Dalain, S.5    Martinez, G.6    Leon, O.S.7    Springer, J.E.8
  • 46
    • 0030590429 scopus 로고    scopus 로고
    • Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: A possible site of prostaglandin synthesis responsible for fever
    • Cao C, Matsumura K, Yamagata K, and Watanabe Y (1996) Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: a possible site of prostaglandin synthesis responsible for fever. Brain Res 733:263-272.
    • (1996) Brain Res , vol.733 , pp. 263-272
    • Cao, C.1    Matsumura, K.2    Yamagata, K.3    Watanabe, Y.4
  • 49
    • 0029033219 scopus 로고
    • Pharmacology of a selective COX-2 inhibitor, L-745,337: A novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate stomach
    • Chan CC, Boyce S, Brideau C, Ford-Hutchinson AW, Gordon R, Guay D, Hill RG, Li CS, Mancini J, and Penneton M (1995) Pharmacology of a selective COX-2 inhibitor, L-745,337: a novel nonsteroidal anti-inflammatory agent with an ulcerogenic sparing effect in rat and nonhuman primate stomach. J Pharmacol Exp Ther 274:1531-1537.
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 1531-1537
    • Chan, C.C.1    Boyce, S.2    Brideau, C.3    Ford-Hutchinson, A.W.4    Gordon, R.5    Guay, D.6    Hill, R.G.7    Li, C.S.8    Mancini, J.9    Penneton, M.10
  • 50
    • 0030391850 scopus 로고    scopus 로고
    • Selective COX-2 inhibitors as potential therapeutic agents for inflammatory diseases
    • Chan CC and Rodger IW (1997) Selective COX-2 inhibitors as potential therapeutic agents for inflammatory diseases. Adv Exp Med Biol 407:157-161.
    • (1997) Adv Exp Med Biol , vol.407 , pp. 157-161
    • Chan, C.C.1    Rodger, I.W.2
  • 51
    • 0033756160 scopus 로고    scopus 로고
    • Cyclooxygenase 2 promotes cell survival by stimulation of dynein light chain expression and inhibition of neuronal nitric oxide synthase activity
    • Chang YW, Jakobi R, McGinty A, Foschi M, Dunn MJ, and Sorokin A (2000) Cyclooxygenase 2 promotes cell survival by stimulation of dynein light chain expression and inhibition of neuronal nitric oxide synthase activity. Mol Cell Biol 20:8571-8579.
    • (2000) Mol Cell Biol , vol.20 , pp. 8571-8579
    • Chang, Y.W.1    Jakobi, R.2    McGinty, A.3    Foschi, M.4    Dunn, M.J.5    Sorokin, A.6
  • 54
    • 0036082805 scopus 로고    scopus 로고
    • Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity
    • Chen C, Magee JC, and Bazan NG (2002) Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity. J Neurophysiol 87: 2851-2857.
    • (2002) J Neurophysiol , vol.87 , pp. 2851-2857
    • Chen, C.1    Magee, J.C.2    Bazan, N.G.3
  • 55
    • 0030005994 scopus 로고    scopus 로고
    • Variable effects of L-arginine analogs on L-arginine-nitric oxide pathway in human neutrophils and platelets may relate to different nitric oxide synthase isoforms
    • Chen LY and Mehta JL (1996) Variable effects of L-arginine analogs on L-arginine-nitric oxide pathway in human neutrophils and platelets may relate to different nitric oxide synthase isoforms. J Pharmacol Exp Ther 276:253-257.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 253-257
    • Chen, L.Y.1    Mehta, J.L.2
  • 56
    • 20644440397 scopus 로고    scopus 로고
    • Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets
    • Chen LY, Salafranca MN, and Mehta JL (1997) Cyclooxygenase inhibition decreases nitric oxide synthase activity in human platelets. Am J Physiol 273:H1854-H1859.
    • (1997) Am J Physiol , vol.273
    • Chen, L.Y.1    Salafranca, M.N.2    Mehta, J.L.3
  • 58
    • 0035045226 scopus 로고    scopus 로고
    • Review: Effects of nitric oxide on eye diseases and their treatment
    • Chiou GC (2001) Review: effects of nitric oxide on eye diseases and their treatment. J Ocul Pharmacol Ther 17:189-198.
    • (2001) J Ocul Pharmacol Ther , vol.17 , pp. 189-198
    • Chiou, G.C.1
  • 59
    • 0025880486 scopus 로고
    • Biochemical and pharmacological interactions between nitroglycerin and thiols. Effects of thiol structure on nitric oxide generation and tolerance reversal
    • Chong S and Fung HL (1991) Biochemical and pharmacological interactions between nitroglycerin and thiols. Effects of thiol structure on nitric oxide generation and tolerance reversal. Biochem J 42:1433-1439.
    • (1991) Biochem J , vol.42 , pp. 1433-1439
    • Chong, S.1    Fung, H.L.2
  • 62
    • 0034013014 scopus 로고    scopus 로고
    • Nitric oxide: An inhibitor of NF-kappaB/Rel system in glial cells
    • Colasanti M and Persichini T (2000) Nitric oxide: an inhibitor of NF-kappaB/Rel system in glial cells. Brain Res Bull 52:155-161.
    • (2000) Brain Res Bull , vol.52 , pp. 155-161
    • Colasanti, M.1    Persichini, T.2
  • 65
    • 0027788115 scopus 로고
    • IL-1 beta induces the coexpression of both NO synthase and COX by islets of Langerhans: Activation of COX by NO
    • Corbett JA, Kwon G, Turk J, and McDaniel ML (1993) IL-1 beta induces the coexpression of both NO synthase and COX by islets of Langerhans: activation of COX by NO. Biochemistry 32:13767-13770.
    • (1993) Biochemistry , vol.32 , pp. 13767-13770
    • Corbett, J.A.1    Kwon, G.2    Turk, J.3    McDaniel, M.L.4
  • 68
    • 0034043548 scopus 로고    scopus 로고
    • Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion
    • Cuzzocrea S, Misko TP, Costantino G, Mazzon E, Micali A, Caputi AP, Macarthur H, and Salvemini D (2000) Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion. FASEB J 14:1061-1072.
    • (2000) FASEB J , vol.14 , pp. 1061-1072
    • Cuzzocrea, S.1    Misko, T.P.2    Costantino, G.3    Mazzon, E.4    Micali, A.5    Caputi, A.P.6    Macarthur, H.7    Salvemini, D.8
  • 69
    • 0031975261 scopus 로고    scopus 로고
    • Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of NO synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation
    • Cuzzocrea S, Zingarelli B, Hake P, Salzman AL, and Szabo C (1998) Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of NO synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation. Free Radic Biol Med 24:450-459.
    • (1998) Free Radic Biol Med , vol.24 , pp. 450-459
    • Cuzzocrea, S.1    Zingarelli, B.2    Hake, P.3    Salzman, A.L.4    Szabo, C.5
  • 71
    • 0029146579 scopus 로고
    • Nitric oxide produced by endothelial cells increases production of eicosanoids through activation of prostaglandin H synthase
    • Davidge ST, Baker PN, Laughlin MK, and Roberts JM (1995) Nitric oxide produced by endothelial cells increases production of eicosanoids through activation of prostaglandin H synthase. Circ Res 77:274-283.
    • (1995) Circ Res , vol.77 , pp. 274-283
    • Davidge, S.T.1    Baker, P.N.2    Laughlin, M.K.3    Roberts, J.M.4
  • 73
  • 75
    • 0029159779 scopus 로고
    • NO decreases cytokine-induced endothelial activation. NO selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines
    • De Caterina R, Libby P, Peng HB, Thannickal VJ, Rajavashisth TB, Gimbrone MA Jr, Shin WS, and Liao JK (1995) NO decreases cytokine-induced endothelial activation. NO selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Investig 96:60-68.
    • (1995) J Clin Investig , vol.96 , pp. 60-68
    • De Caterina, R.1    Libby, P.2    Peng, H.B.3    Thannickal, V.J.4    Rajavashisth, T.B.5    Gimbrone Jr., M.A.6    Shin, W.S.7    Liao, J.K.8
  • 76
    • 0025338045 scopus 로고
    • Inhibition of platelet function during in vivo infusion of isosorbide mononitrates: Relationship between plasma drug concentration and hemodynamic effects
    • De Caterina R, Lombardi M, Bernini W, Giannessi D, Gazzetti P, and L'Abbate A (1990) Inhibition of platelet function during in vivo infusion of isosorbide mononitrates: relationship between plasma drug concentration and hemodynamic effects. Am Heart J 119:855-862.
    • (1990) Am Heart J , vol.119 , pp. 855-862
    • De Caterina, R.1    Lombardi, M.2    Bernini, W.3    Giannessi, D.4    Gazzetti, P.5    L'Abbate, A.6
  • 77
    • 0033103672 scopus 로고    scopus 로고
    • Cyclooxygenases-1 and -2 are differentially localized to microglia and endothelium in rat EAE and glioma
    • Deininger MH and Schluesener HJ (1999) Cyclooxygenases-1 and -2 are differentially localized to microglia and endothelium in rat EAE and glioma. J Neuroimmunol 95:202-208.
    • (1999) J Neuroimmunol , vol.95 , pp. 202-208
    • Deininger, M.H.1    Schluesener, H.J.2
  • 78
    • 0031829139 scopus 로고    scopus 로고
    • Differential effects of nitric oxide-mediated S-nitrosylation on p50 and c-jun DNA binding
    • DelaTorre A, Schroeder RA, Bartlett ST, and Kuo PC (1998) Differential effects of nitric oxide-mediated S-nitrosylation on p50 and c-jun DNA binding. Surgery 124:137-141.
    • (1998) Surgery , vol.124 , pp. 137-141
    • DelaTorre, A.1    Schroeder, R.A.2    Bartlett, S.T.3    Kuo, P.C.4
  • 79
    • 0031590264 scopus 로고    scopus 로고
    • Alteration of NF-kappa B p50 DNA binding kinetics by S-nitrosylation
    • DelaTorre A, Schroeder RA, and Kuo PC (1997) Alteration of NF-kappa B p50 DNA binding kinetics by S-nitrosylation. Biochem Biophys Res Commun 238:703-706.
    • (1997) Biochem Biophys Res Commun , vol.238 , pp. 703-706
    • DelaTorre, A.1    Schroeder, R.A.2    Kuo, P.C.3
  • 80
    • 0032802682 scopus 로고    scopus 로고
    • NO-aspirins, a class of new anti-inflammatory and anti-thrombotic agents
    • del Soldato P, Sorrentino R, and Pinto A (1999) NO-aspirins, a class of new anti-inflammatory and anti-thrombotic agents. Trends Pharmacol Sci 20:319-323.
    • (1999) Trends Pharmacol Sci , vol.20 , pp. 319-323
    • Del Soldato, P.1    Sorrentino, R.2    Pinto, A.3
  • 81
    • 0023968630 scopus 로고
    • Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence
    • DeWitt DL and Smith WL (1988) Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence. Proc Natl Acad Sci USA 85:1412-1416.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1412-1416
    • DeWitt, D.L.1    Smith, W.L.2
  • 82
    • 0344052682 scopus 로고    scopus 로고
    • Dual effect of nitric oxide donors on cyclooxygenase-2 expression in human mesangial cells
    • Diaz-Cazorla M, Perez-Sala D, and Lamas S (1999) Dual effect of nitric oxide donors on cyclooxygenase-2 expression in human mesangial cells. J Am Soc Nephrol 10:943-952.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 943-952
    • Diaz-Cazorla, M.1    Perez-Sala, D.2    Lamas, S.3
  • 83
    • 0028326424 scopus 로고
    • Endothelial NO synthase localized to hippocampal pyramidal cells: Implications for synaptic plasticity
    • Dinerman JL, Dawson TM, Schell MJ, Snowman A, and Snyder SH (1994) Endothelial NO synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity. Proc Natl Acad Sci USA 91:4214-4218.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4214-4218
    • Dinerman, J.L.1    Dawson, T.M.2    Schell, M.J.3    Snowman, A.4    Snyder, S.H.5
  • 84
    • 0027202456 scopus 로고
    • Molecular mechanisms of NO regulation. Potential relevance to cardiovascular disease
    • Dinerman JL, Lowenstein CJ, and Snyder SH (1993) Molecular mechanisms of NO regulation. Potential relevance to cardiovascular disease. Circ Res 73:217-222.
    • (1993) Circ Res , vol.73 , pp. 217-222
    • Dinerman, J.L.1    Lowenstein, C.J.2    Snyder, S.H.3
  • 86
    • 0035930486 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitor NS398 preserves neuronal function after hypoxia/ischemia in piglets
    • Domoki F, Perciaccante JV, Puskar M, Bari F, and Busija DW (2001) Cyclooxygenase-2 inhibitor NS398 preserves neuronal function after hypoxia/ischemia in piglets. Neuroreport 12:4065-4068.
    • (2001) Neuroreport , vol.12 , pp. 4065-4068
    • Domoki, F.1    Perciaccante, J.V.2    Puskar, M.3    Bari, F.4    Busija, D.W.5
  • 87
    • 0023898677 scopus 로고
    • Actions of nitric oxide on the release of prostacyclin from bovine endothelial cells in culture
    • Doni MG, Whittle BJ, Palmer RM, and Moncada S (1988) Actions of nitric oxide on the release of prostacyclin from bovine endothelial cells in culture. Eur J Pharmacol 151:19-25.
    • (1988) Eur J Pharmacol , vol.151 , pp. 19-25
    • Doni, M.G.1    Whittle, B.J.2    Palmer, R.M.3    Moncada, S.4
  • 89
    • 0017091041 scopus 로고
    • Mechanism for irreversible self-deactivation of PG synthetase
    • Egan RW, Paxton J, and Kuehl FA Jr (1976) Mechanism for irreversible self-deactivation of PG synthetase. J Biol Chem 251:7329-7335.
    • (1976) J Biol Chem , vol.251 , pp. 7329-7335
    • Egan, R.W.1    Paxton, J.2    Kuehl Jr., F.A.3
  • 90
    • 0030914284 scopus 로고    scopus 로고
    • Neuronal NO synthase alternatively spliced forms: Prominent functional localizations in the brain
    • Eliasson MJ, Blackshaw S, Schell MJ, and Snyder SH (1997) Neuronal NO synthase alternatively spliced forms: prominent functional localizations in the brain. Proc Natl Acad Sci USA 94:3396-3401.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3396-3401
    • Eliasson, M.J.1    Blackshaw, S.2    Schell, M.J.3    Snyder, S.H.4
  • 91
    • 0027289707 scopus 로고
    • Reactive astrocytes express NADPH diaphorase in vivo after transient ischemia
    • Endoh M, Maiese K, Pulsinelli WA, and Wagner JA (1993) Reactive astrocytes express NADPH diaphorase in vivo after transient ischemia. Neurosci Lett 154: 125-128.
    • (1993) Neurosci Lett , vol.154 , pp. 125-128
    • Endoh, M.1    Maiese, K.2    Pulsinelli, W.A.3    Wagner, J.A.4
  • 92
    • 0036196417 scopus 로고    scopus 로고
    • NO as a signaling molecule in the nervous system
    • Esplugues JV (2002) NO as a signaling molecule in the nervous system. Br J Pharmacol 135:1079-1095.
    • (2002) Br J Pharmacol , vol.135 , pp. 1079-1095
    • Esplugues, J.V.1
  • 93
    • 0036208533 scopus 로고    scopus 로고
    • The MDR phenotype is associated with the expression of COX-2 and iNOS in a human hepatocellular carcinoma cell line
    • Fantappiè O, Masini E, Sardi I, Raimondi L, Bani D, Solazzo M, Vannacci A, and Mazzanti R (2002) The MDR phenotype is associated with the expression of COX-2 and iNOS in a human hepatocellular carcinoma cell line. Hepatology 35:843-852.
    • (2002) Hepatology , vol.35 , pp. 843-852
    • Fantappiè, O.1    Masini, E.2    Sardi, I.3    Raimondi, L.4    Bani, D.5    Solazzo, M.6    Vannacci, A.7    Mazzanti, R.8
  • 94
    • 0025817680 scopus 로고
    • The biochemical pathways of nitric oxide formation from nitrovasodilators: Appropriate choice of exogenous NO donors and aspects of preparation and handling of aqueous NO solutions
    • Feelisch M (1991) The biochemical pathways of nitric oxide formation from nitrovasodilators: appropriate choice of exogenous NO donors and aspects of preparation and handling of aqueous NO solutions. J Cardiovasc Pharmacol 17:S25-S33.
    • (1991) J Cardiovasc Pharmacol , vol.17
    • Feelisch, M.1
  • 95
    • 0026009586 scopus 로고
    • Biotransformation of organic nitrates to nitric oxide by vascular smooth muscle and endothelial cells
    • Feelisch M and Kelm M (1991) Biotransformation of organic nitrates to nitric oxide by vascular smooth muscle and endothelial cells. Biochem Biophys Res Commun 180:286-293.
    • (1991) Biochem Biophys Res Commun , vol.180 , pp. 286-293
    • Feelisch, M.1    Kelm, M.2
  • 96
    • 0023277458 scopus 로고
    • Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase
    • Feelisch M and Noack E (1987) Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase. Eur J Pharmacol 139:19-30.
    • (1987) Eur J Pharmacol , vol.139 , pp. 19-30
    • Feelisch, M.1    Noack, E.2
  • 97
    • 0027458692 scopus 로고
    • Irreversible inactivation of macrophage and brain NO synthase by L-NG-methylarginine requires NADPH-dependent hydroxylation
    • Feldman PL, Griffith OW, Hong H, and Stuehr DJ (1993) Irreversible inactivation of macrophage and brain NO synthase by L-NG-methylarginine requires NADPH-dependent hydroxylation. J Med Chem 36:491-496.
    • (1993) J Med Chem , vol.36 , pp. 491-496
    • Feldman, P.L.1    Griffith, O.W.2    Hong, H.3    Stuehr, D.J.4
  • 98
    • 0029787241 scopus 로고    scopus 로고
    • Endothelial NO synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells
    • Feron O, Belhassen L, Kobzik L, Smith TW, Kelly RA, and Michel T (1996) Endothelial NO synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells. J Biol Chem 271:22810-22814.
    • (1996) J Biol Chem , vol.271 , pp. 22810-22814
    • Feron, O.1    Belhassen, L.2    Kobzik, L.3    Smith, T.W.4    Kelly, R.A.5    Michel, T.6
  • 99
    • 0015511847 scopus 로고
    • Inhibition of PG synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol)
    • Flower RJ and Vane JR (1972) Inhibition of PG synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol). Nature (Lond) 240:410-411.
    • (1972) Nature (Lond) , vol.240 , pp. 410-411
    • Flower, R.J.1    Vane, J.R.2
  • 100
    • 0035917849 scopus 로고    scopus 로고
    • Nitroaspirin (NCX 4016) reduces brain damage induced by focal cerebral ischemia in rat
    • Fredduzzi S, Mariucci G, Tantucci M, Del Soldato P, and Ambrosini MV (2001) Nitroaspirin (NCX 4016) reduces brain damage induced by focal cerebral ischemia in rat. Neurosci Lett 302:121-124.
    • (2001) Neurosci Lett , vol.302 , pp. 121-124
    • Fredduzzi, S.1    Mariucci, G.2    Tantucci, M.3    Del Soldato, P.4    Ambrosini, M.V.5
  • 101
    • 0032514666 scopus 로고    scopus 로고
    • Impaired platelet production of nitric oxide predicts presence of acute coronary syndromes
    • Freedman JE, Ting B, Hankin B, Loscalzo J, Keaney JF Jr, and Vita JA (1998) Impaired platelet production of nitric oxide predicts presence of acute coronary syndromes. Circulation 98:1481-1486.
    • (1998) Circulation , vol.98 , pp. 1481-1486
    • Freedman, J.E.1    Ting, B.2    Hankin, B.3    Loscalzo, J.4    Keaney Jr., J.F.5    Vita, J.A.6
  • 102
    • 0032579898 scopus 로고    scopus 로고
    • Quality-of-life considerations with respect to arthritis and nonsteroidal anti-inflammatory drugs
    • Fries JF (1998) Quality-of-life considerations with respect to arthritis and nonsteroidal anti-inflammatory drugs. Am J Med 104:14S-20S; discussion 21S-22S.
    • (1998) Am J Med , vol.104
    • Fries, J.F.1
  • 103
    • 0027422994 scopus 로고
    • Peracid oxidation of an N-hydroxyguanidine compound: A chemical model for the oxidation of N omega-hydroxyl-L-arginine by NO synthase
    • Fukuto JM, Stuehr DJ, Feldman PL, Bova MP, and Wong P (1993) Peracid oxidation of an N-hydroxyguanidine compound: a chemical model for the oxidation of N omega-hydroxyl-L-arginine by NO synthase. J Med Chem 36:2666-2670.
    • (1993) J Med Chem , vol.36 , pp. 2666-2670
    • Fukuto, J.M.1    Stuehr, D.J.2    Feldman, P.L.3    Bova, M.P.4    Wong, P.5
  • 104
    • 0026512737 scopus 로고
    • Chemical oxidation of N-hydroxyguanidine compounds. Release of NO, nitroxyl and possible relationship to the mechanism of biological NO generation
    • Fukuto JM, Wallace GC, Hszieh R, and Chaudhuri G (1992) Chemical oxidation of N-hydroxyguanidine compounds. Release of NO, nitroxyl and possible relationship to the mechanism of biological NO generation. Biochem Pharmacol 43:607-613.
    • (1992) Biochem Pharmacol , vol.43 , pp. 607-613
    • Fukuto, J.M.1    Wallace, G.C.2    Hszieh, R.3    Chaudhuri, G.4
  • 105
    • 0035192750 scopus 로고    scopus 로고
    • Post-translational control of endothelial NO synthase: Why isn't calcium/calmodulin enough?
    • Fulton D, Gratton JP, and Sessa WC (2001) Post-translational control of endothelial NO synthase: why isn't calcium/calmodulin enough? J Pharmacol Exp Ther 299:818-824.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 818-824
    • Fulton, D.1    Gratton, J.P.2    Sessa, W.C.3
  • 106
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott RF and Zawadzki JV (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature (Lond) 288:373-376.
    • (1980) Nature (Lond) , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 107
    • 0027967765 scopus 로고
    • Potent and selective inhibition of human NO synthases. Selective inhibition of neuronal NO synthase by S-methyl-L- thiocitrulline and S-ethyl-L-thiocitrulline
    • Furfine ES, Harmon MF, Paith JE, Knowles RG, Salter M, Kiff RJ, Duffy C, Hazelwood R, Oplinger JA, and Garvey EP (1994) Potent and selective inhibition of human NO synthases. Selective inhibition of neuronal NO synthase by S-methyl-L- thiocitrulline and S-ethyl-L-thiocitrulline. J Biol Chem 269:26677-26683.
    • (1994) J Biol Chem , vol.269 , pp. 26677-26683
    • Furfine, E.S.1    Harmon, M.F.2    Paith, J.E.3    Knowles, R.G.4    Salter, M.5    Kiff, R.J.6    Duffy, C.7    Hazelwood, R.8    Oplinger, J.A.9    Garvey, E.P.10
  • 108
    • 0027516402 scopus 로고
    • NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions
    • Futaki N, Yoshikawa K, Hamasaka Y, Arai I, Higuchi S, Iizuka H, and Otomo S (1993) NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. Gen Pharmacol 24:105-110.
    • (1993) Gen Pharmacol , vol.24 , pp. 105-110
    • Futaki, N.1    Yoshikawa, K.2    Hamasaka, Y.3    Arai, I.4    Higuchi, S.5    Iizuka, H.6    Otomo, S.7
  • 110
    • 0034099703 scopus 로고    scopus 로고
    • Treatment of the contralateral negative neck in supraglottic cancer patients with unilateral node metastases (N1-3)
    • Gallo O, Fini-Storchi I, and Napolitano L (2000) Treatment of the contralateral negative neck in supraglottic cancer patients with unilateral node metastases (N1-3). Head Neck 22:386-392.
    • (2000) Head Neck , vol.22 , pp. 386-392
    • Gallo, O.1    Fini-Storchi, I.2    Napolitano, L.3
  • 113
    • 0024553336 scopus 로고
    • NO-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
    • Garg UC and Hassid A (1989) NO-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Investig 83:1774-1777.
    • (1989) J Clin Investig , vol.83 , pp. 1774-1777
    • Garg, U.C.1    Hassid, A.2
  • 114
    • 0026077959 scopus 로고
    • Glutamate, NO and cell-cell signalling in the nervous system
    • Garthwaite J (1991) Glutamate, NO and cell-cell signalling in the nervous system. Trends Neurosci 14:60-67.
    • (1991) Trends Neurosci , vol.14 , pp. 60-67
    • Garthwaite, J.1
  • 115
    • 0028917372 scopus 로고
    • NO signaling in the central nervous system
    • Garthwaite J and Boulton CL (1995) NO signaling in the central nervous system. Annu Rev Physiol 57:683-706.
    • (1995) Annu Rev Physiol , vol.57 , pp. 683-706
    • Garthwaite, J.1    Boulton, C.L.2
  • 116
    • 0031040613 scopus 로고    scopus 로고
    • 1400W is a slow, tight binding and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo
    • Garvey EP, Oplinger JA, Furfine ES, Kiff RJ, Laszlo F, Whittle BJ, and Knowles RG (1997) 1400W is a slow, tight binding and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo. J Biol Chem 272:4959-4963.
    • (1997) J Biol Chem , vol.272 , pp. 4959-4963
    • Garvey, E.P.1    Oplinger, J.A.2    Furfine, E.S.3    Kiff, R.J.4    Laszlo, F.5    Whittle, B.J.6    Knowles, R.G.7
  • 118
    • 0032613064 scopus 로고    scopus 로고
    • Update on clinical developments with celecoxib, a new specific COX-2 inhibitor: What can we expect?
    • Geis GS (1999) Update on clinical developments with celecoxib, a new specific COX-2 inhibitor: what can we expect? J Rheumatol 26 (Suppl 56):31-36.
    • (1999) J Rheumatol , vol.26 , Issue.56 SUPPL. , pp. 31-36
    • Geis, G.S.1
  • 119
    • 0026440742 scopus 로고
    • Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: Implications for the neuropathogenesis of HIV disease
    • Genis P, Jett M, Bernton EW, Boyle T, Gelbard HA, Dzenko K, Keane RW, Resnick L, Mizrachi Y, Volsky DJ, et al. (1992) Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophageastroglia interactions: implications for the neuropathogenesis of HIV disease. J Exp Med 176:1703-1718.
    • (1992) J Exp Med , vol.176 , pp. 1703-1718
    • Genis, P.1    Jett, M.2    Bernton, E.W.3    Boyle, T.4    Gelbard, H.A.5    Dzenko, K.6    Keane, R.W.7    Resnick, L.8    Mizrachi, Y.9    Volsky, D.J.10
  • 121
    • 0031748727 scopus 로고    scopus 로고
    • Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation and oxidant-induced apoptosis
    • Giardino I, Fard AK, Hatchell DL, and Brownlee M (1998) Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation and oxidant-induced apoptosis. Diabetes 47:1114-1120.
    • (1998) Diabetes , vol.47 , pp. 1114-1120
    • Giardino, I.1    Fard, A.K.2    Hatchell, D.L.3    Brownlee, M.4
  • 122
    • 0029740064 scopus 로고    scopus 로고
    • Localization of prostaglandin H synthase type 2 protein and mRNA in term human fetal membranes and decidua
    • Gibb W and Sun M (1996) Localization of prostaglandin H synthase type 2 protein and mRNA in term human fetal membranes and decidua. J Endocrinol 150:497-503.
    • (1996) J Endocrinol , vol.150 , pp. 497-503
    • Gibb, W.1    Sun, M.2
  • 124
    • 0036968944 scopus 로고    scopus 로고
    • Beta-amyloid-induced inflammation and cholinergic hypofunction in the rat brain in vivo: Involvement of the p38 MAPK pathway
    • Giovannini MG, Scali C, Prosperi C, Bellucci A, Vannucchi MG, Rosi S, Pepeu G, and Casamenti F (2002) Beta-amyloid-induced inflammation and cholinergic hypofunction in the rat brain in vivo: involvement of the p38 MAPK pathway. Neurobiol Dis 11:257-274.
    • (2002) Neurobiol Dis , vol.11 , pp. 257-274
    • Giovannini, M.G.1    Scali, C.2    Prosperi, C.3    Bellucci, A.4    Vannucchi, M.G.5    Rosi, S.6    Pepeu, G.7    Casamenti, F.8
  • 127
    • 0034485450 scopus 로고    scopus 로고
    • Neuronal NO synthase inhibitor has a neuroprotective effect in a rat model of brain injury
    • Gorlach C, Hortobagyi T, Hortobagyi S, and Benyo Z (2000) Neuronal NO synthase inhibitor has a neuroprotective effect in a rat model of brain injury. Restor Neurol Neurosci 17:71-76.
    • (2000) Restor Neurol Neurosci , vol.17 , pp. 71-76
    • Gorlach, C.1    Hortobagyi, T.2    Hortobagyi, S.3    Benyo, Z.4
  • 129
    • 0027511113 scopus 로고
    • Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from L-arginine and protection against Francisella tularensis infection in Mycobacterium bovis BCG-treated mice
    • Green SJ, Nacy CA, Schreiber RD, Granger DL, Crawford RM, Meltzer MS, and Fortier AH (1993) Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from L-arginine and protection against Francisella tularensis infection in Mycobacterium bovis BCG-treated mice. Infect Immun 61:689-698.
    • (1993) Infect Immun , vol.61 , pp. 689-698
    • Green, S.J.1    Nacy, C.A.2    Schreiber, R.D.3    Granger, D.L.4    Crawford, R.M.5    Meltzer, M.S.6    Fortier, A.H.7
  • 130
  • 131
    • 0029912242 scopus 로고    scopus 로고
    • Inhibitors of the proteasome pathway interfere with induction of NO synthase in macrophages by blocking activation of transcription factor NF-kappa B
    • Griscavage JM, Wilk S, and Ignarro LJ (1996) Inhibitors of the proteasome pathway interfere with induction of NO synthase in macrophages by blocking activation of transcription factor NF-kappa B. Proc Natl Acad Sci USA 93:3308-3312.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3308-3312
    • Griscavage, J.M.1    Wilk, S.2    Ignarro, L.J.3
  • 132
    • 0032910873 scopus 로고    scopus 로고
    • NO. I. Physiological chemistry of NO and its metabolites: Implications in inflammation
    • Grisham MB, Jourd'heuil D, and Wink DA (1999) NO. I. Physiological chemistry of NO and its metabolites: implications in inflammation. Am J Physiol 276:G315-G321.
    • (1999) Am J Physiol , vol.276
    • Grisham, M.B.1    Jourd'heuil, D.2    Wink, D.A.3
  • 134
    • 0022640297 scopus 로고
    • Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
    • Gryglewski RJ, Palmer RM, and Moncada S (1986) Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature (Lond) 320:454-456.
    • (1986) Nature (Lond) , vol.320 , pp. 454-456
    • Gryglewski, R.J.1    Palmer, R.M.2    Moncada, S.3
  • 135
    • 0030610936 scopus 로고    scopus 로고
    • Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells
    • Guastadisegni C, Minghetti L, Nicolini A, Polazzi E, Ade P, Balduzzi M, and Levi G (1997) Prostaglandin E2 synthesis is differentially affected by reactive nitrogen intermediates in cultured rat microglia and RAW 264.7 cells. FEBS Lett 413:314-318.
    • (1997) FEBS Lett , vol.413 , pp. 314-318
    • Guastadisegni, C.1    Minghetti, L.2    Nicolini, A.3    Polazzi, E.4    Ade, P.5    Balduzzi, M.6    Levi, G.7
  • 136
    • 0029666486 scopus 로고    scopus 로고
    • Role of Val509 in timedependent inhibition of human prostaglandin H synthase-2 cyclooxygenase activity by isoform-selective agents
    • Guo Q, Wang LH, Ruan KH, and Kulmacz RJ (1996) Role of Val509 in timedependent inhibition of human prostaglandin H synthase-2 cyclooxygenase activity by isoform-selective agents. J Biol Chem 271:19134-19139.
    • (1996) J Biol Chem , vol.271 , pp. 19134-19139
    • Guo, Q.1    Wang, L.H.2    Ruan, K.H.3    Kulmacz, R.J.4
  • 138
    • 0029163992 scopus 로고
    • NO enhances prostaglandin-H synthase activity by a heme-independent mechanism: Evidence implicating nitrosothiols
    • Hajjar D, Lander H, Pearce F, Upmacis R, and Pomerantz K (1995) NO enhances prostaglandin-H synthase activity by a heme-independent mechanism: evidence implicating nitrosothiols. J Am Chem Soc 117:3340-3346.
    • (1995) J Am Chem Soc , vol.117 , pp. 3340-3346
    • Hajjar, D.1    Lander, H.2    Pearce, F.3    Upmacis, R.4    Pomerantz, K.5
  • 141
    • 0028034970 scopus 로고
    • Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction
    • Harris RC, McKanna JA, Akai Y, Jacobson HR, Dubois RN, and Breyer MD (1994) Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J Clin Investig 94:2504-2510.
    • (1994) J Clin Investig , vol.94 , pp. 2504-2510
    • Harris, R.C.1    McKanna, J.A.2    Akai, Y.3    Jacobson, H.R.4    Dubois, R.N.5    Breyer, M.D.6
  • 142
    • 0033169233 scopus 로고    scopus 로고
    • Interleukin-1beta, inducible nitric oxide synthase and nuclear factor-kappaB are induced in morphologically distinct microglia after rat hippocampal lipopolysaccharide/interferon-gamma injection
    • Hartlage-Rubsamen M, Lemke R, and Schliebs R (1999) Interleukin-1beta, inducible nitric oxide synthase and nuclear factor-kappaB are induced in morphologically distinct microglia after rat hippocampal lipopolysaccharide/ interferon-gamma injection. J Neurosci Res 57:388-398.
    • (1999) J Neurosci Res , vol.57 , pp. 388-398
    • Hartlage-Rubsamen, M.1    Lemke, R.2    Schliebs, R.3
  • 143
    • 0030338041 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drug gastropathy: Causes and treatment
    • Hawkey CJ (1996) Non-steroidal anti-inflammatory drug gastropathy: causes and treatment. Scand J Gastroenterol Suppl 220:124-127.
    • (1996) Scand J Gastroenterol Suppl , vol.220 , pp. 124-127
    • Hawkey, C.J.1
  • 144
    • 0032477593 scopus 로고    scopus 로고
    • Helicobacter pylori, NSAIDs and peptic ulcers
    • Hawkey CJ, Yeomans ND, and Gillon K (1998) Helicobacter pylori, NSAIDs and peptic ulcers. Lancet 351:61-62.
    • (1998) Lancet , vol.351 , pp. 61-62
    • Hawkey, C.J.1    Yeomans, N.D.2    Gillon, K.3
  • 145
    • 0017094438 scopus 로고
    • Purification of the COX that forms prostaglandins. Demonstration of two forms of iron in the holoenzyme
    • Hemler M and Lands WE (1976) Purification of the COX that forms prostaglandins. Demonstration of two forms of iron in the holoenzyme. J Biol Chem 251:5575-5579.
    • (1976) J Biol Chem , vol.251 , pp. 5575-5579
    • Hemler, M.1    Lands, W.E.2
  • 146
    • 8944227048 scopus 로고    scopus 로고
    • Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: Results of a collaborative meta-analysis
    • Henry D, Lim LL, Garcia Rodriguez LA, Perez GS, Carson JL, Griffin M, Savage R, Logan R, Moride Y, Hawkey C, et al. (1996) Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysis. Br Med J 312:1563-1566.
    • (1996) Br Med J , vol.312 , pp. 1563-1566
    • Henry, D.1    Lim, L.L.2    Garcia Rodriguez, L.A.3    Perez, G.S.4    Carson, J.L.5    Griffin, M.6    Savage, R.7    Logan, R.8    Moride, Y.9    Hawkey, C.10
  • 148
    • 0033081642 scopus 로고    scopus 로고
    • Interferon-gamma reduces cyclooxygenase-2-mediated prostaglandin E2 production from primary mouse astrocytes independent of nitric oxide formation
    • Hewett SJ (1999) Interferon-gamma reduces cyclooxygenase-2-mediated prostaglandin E2 production from primary mouse astrocytes independent of nitric oxide formation. J Neuroimmunol 94:134-143.
    • (1999) J Neuroimmunol , vol.94 , pp. 134-143
    • Hewett, S.J.1
  • 150
    • 0035044457 scopus 로고    scopus 로고
    • The potential of selective COX-2 inhibitors in inflammatory and other diseases
    • Ho L and Pasinetti GM (2001) The potential of selective COX-2 inhibitors in inflammatory and other diseases. Drugs Today (Barc) 37:181-185.
    • (2001) Drugs Today (Barc) , vol.37 , pp. 181-185
    • Ho, L.1    Pasinetti, G.M.2
  • 151
    • 0027948425 scopus 로고
    • Formation of free NO from L-arginine by NO synthase: Direct enhancement of generation by superoxide dismutase
    • Hobbs AJ, Fukuto JM, and Ignarro LJ (1994) Formation of free NO from L-arginine by NO synthase: direct enhancement of generation by superoxide dismutase. Proc Natl Acad Sci USA 91:10992-10996.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10992-10996
    • Hobbs, A.J.1    Fukuto, J.M.2    Ignarro, L.J.3
  • 152
    • 0032948112 scopus 로고    scopus 로고
    • Inhibition of NO synthase as a potential therapeutic target
    • Hobbs AJ, Higgs A, and Moncada S (1999) Inhibition of NO synthase as a potential therapeutic target. Annu Rev Pharmacol Toxicol 39:191-220.
    • (1999) Annu Rev Pharmacol Toxicol , vol.39 , pp. 191-220
    • Hobbs, A.J.1    Higgs, A.2    Moncada, S.3
  • 153
    • 0026478029 scopus 로고
    • An inhibitor of NO synthesis prevents memory formation in the chick
    • Holscher C and Rose SP (1992) An inhibitor of NO synthesis prevents memory formation in the chick. Neurosci Lett 145:165-167.
    • (1992) Neurosci Lett , vol.145 , pp. 165-167
    • Holscher, C.1    Rose, S.P.2
  • 154
    • 0032483514 scopus 로고    scopus 로고
    • Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells
    • Hood J and Granger HJ (1998) Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells. J Biol Chem 273:23504-23508.
    • (1998) J Biol Chem , vol.273 , pp. 23504-23508
    • Hood, J.1    Granger, H.J.2
  • 155
    • 0034745370 scopus 로고    scopus 로고
    • Interleukin-1beta induced cyclooxygenase 2 expression and prostaglandin E2 secretion by human neuroblastoma cells: Implications for Alzheimer's disease
    • Hoozemans JJ, Veerhuis R, Janssen I, Rozemuller AJ, and Eikelenboom P (2001) Interleukin-1beta induced cyclooxygenase 2 expression and prostaglandin E2 secretion by human neuroblastoma cells: implications for Alzheimer's disease. Exp Gerontol 36:559-570.
    • (2001) Exp Gerontol , vol.36 , pp. 559-570
    • Hoozemans, J.J.1    Veerhuis, R.2    Janssen, I.3    Rozemuller, A.J.4    Eikelenboom, P.5
  • 157
    • 0033556017 scopus 로고    scopus 로고
    • Cytokine-induced prostaglandin E2 synthesis and COX-2 activity are regulated both by a NO-dependent and -independent mechanism in rat osteoblasts in vitro
    • Hughes FJ, Buttery LD, Hukkanen MV, O'Donnell A, Maclouf J, and Polak JM (1999) Cytokine-induced prostaglandin E2 synthesis and COX-2 activity are regulated both by a NO-dependent and -independent mechanism in rat osteoblasts in vitro. J Biol Chem 274:1776-1782.
    • (1999) J Biol Chem , vol.274 , pp. 1776-1782
    • Hughes, F.J.1    Buttery, L.D.2    Hukkanen, M.V.3    O'Donnell, A.4    Maclouf, J.5    Polak, J.M.6
  • 158
    • 0036230270 scopus 로고    scopus 로고
    • Pathways of inflammatory activation in Alzheimer's disease: Potential targets for disease modifying drugs
    • Hull M, Lieb K, and Fiebich BL (2002) Pathways of inflammatory activation in Alzheimer's disease: potential targets for disease modifying drugs. Curr Med Chem 9:83-88.
    • (2002) Curr Med Chem , vol.9 , pp. 83-88
    • Hull, M.1    Lieb, K.2    Fiebich, B.L.3
  • 159
    • 0036163960 scopus 로고    scopus 로고
    • Cyclooxygenase inhibition as a strategy to ameliorate brain injury
    • Hurley SD, Olschowka JA, and O'Banion MK (2002) Cyclooxygenase inhibition as a strategy to ameliorate brain injury. J Neurotrauma 19:1-15.
    • (2002) J Neurotrauma , vol.19 , pp. 1-15
    • Hurley, S.D.1    Olschowka, J.A.2    O'Banion, M.K.3
  • 160
    • 0030664096 scopus 로고    scopus 로고
    • Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible NO synthase gene
    • Iadecola C, Zhang F, Casey R, Nagayama M, and Ross ME (1997) Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible NO synthase gene. J Neurosci 17:9157-9164.
    • (1997) J Neurosci , vol.17 , pp. 9157-9164
    • Iadecola, C.1    Zhang, F.2    Casey, R.3    Nagayama, M.4    Ross, M.E.5
  • 161
    • 0027481355 scopus 로고
    • Role of NO synthase-containing vascular nerves in cerebrovasodilation elicited from cerebellum
    • Iadecola C, Zhang F, and Xu X (1993) Role of NO synthase-containing vascular nerves in cerebrovasodilation elicited from cerebellum. Am J Physiol 264:R738-R746.
    • (1993) Am J Physiol , vol.264
    • Iadecola, C.1    Zhang, F.2    Xu, X.3
  • 162
    • 0035957368 scopus 로고    scopus 로고
    • Role of the arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation
    • Ignarro LJ, Buga GM, Wei LH, Bauer PM, Wu G, and del Soldato P (2001) Role of the arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferation. Proc Natl Acad Sci USA 98:4202-4208.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4202-4208
    • Ignarro, L.J.1    Buga, G.M.2    Wei, L.H.3    Bauer, P.M.4    Wu, G.5    Del Soldato, P.6
  • 163
    • 0023505509 scopus 로고
    • Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
    • Ignarro LJ, Buga GM, Wood KS, Byrns RE, and Chaudhuri G (1987) Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA 84:9265-9269.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 9265-9269
    • Ignarro, L.J.1    Buga, G.M.2    Wood, K.S.3    Byrns, R.E.4    Chaudhuri, G.5
  • 164
    • 0027184205 scopus 로고
    • Oxidation of NO in aqueous solution to nitrite but not nitrate: Comparison with enzymatically formed NO from L-arginine
    • Ignarro LJ, Fukuto JM, Griscavage JM, Rogers NE, and Byrns RE (1993) Oxidation of NO in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed NO from L-arginine. Proc Natl Acad Sci USA 90:8103-8107.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8103-8107
    • Ignarro, L.J.1    Fukuto, J.M.2    Griscavage, J.M.3    Rogers, N.E.4    Byrns, R.E.5
  • 165
    • 0037059510 scopus 로고    scopus 로고
    • Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: An overview
    • Ignarro LJ, Napoli C, and Loscalzo J (2002) Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview. Circ Res 90:21-28.
    • (2002) Circ Res , vol.90 , pp. 21-28
    • Ignarro, L.J.1    Napoli, C.2    Loscalzo, J.3
  • 166
    • 0027292458 scopus 로고
    • NO mediates interleukin-1-induced prostaglandin E2 production by vascular smooth muscle cells
    • Inoue T, Fukuo K, Morimoto S, Koh E, and Ogihara T (1993) NO mediates interleukin-1-induced prostaglandin E2 production by vascular smooth muscle cells. Biochem Biophys Res Commun 194:420-424.
    • (1993) Biochem Biophys Res Commun , vol.194 , pp. 420-424
    • Inoue, T.1    Fukuo, K.2    Morimoto, S.3    Koh, E.4    Ogihara, T.5
  • 168
    • 0030239695 scopus 로고    scopus 로고
    • Endogenous nitric oxide activates prostaglandin F2 alpha production in human microglial cells but not in astrocytes: A study of interactions between eicosanoids, nitric oxide and superoxide anion (O2-) regulatory pathways
    • Janabi N, Chabrier S, and Tardieu M (1996) Endogenous nitric oxide activates prostaglandin F2 alpha production in human microglial cells but not in astrocytes: a study of interactions between eicosanoids, nitric oxide and superoxide anion (O2-) regulatory pathways. J Immunol 157:2129-2135.
    • (1996) J Immunol , vol.157 , pp. 2129-2135
    • Janabi, N.1    Chabrier, S.2    Tardieu, M.3
  • 169
    • 0027048906 scopus 로고
    • Treatment of nonsteroidal anti-inflammatory drug-induced gastric ulcers with misoprostol. A double-blind multicenter study
    • Jaszewski R, Graham DY, and Stromatt SC (1992) Treatment of nonsteroidal anti-inflammatory drug-induced gastric ulcers with misoprostol. A double-blind multicenter study. Dig Dis Sci 37:1820-1824.
    • (1992) Dig Dis Sci , vol.37 , pp. 1820-1824
    • Jaszewski, R.1    Graham, D.Y.2    Stromatt, S.C.3
  • 170
  • 173
    • 0021837333 scopus 로고
    • Dose requirements and hemodynamic effects of transdermal nitroglycerin compared to placebo
    • Jordan RA, Seth L, Henri DA, Wilen MM, and Franciosa JA (1985) Dose requirements and hemodynamic effects of transdermal nitroglycerin compared to placebo. Circulation 71:980-985.
    • (1985) Circulation , vol.71 , pp. 980-985
    • Jordan, R.A.1    Seth, L.2    Henri, D.A.3    Wilen, M.M.4    Franciosa, J.A.5
  • 174
    • 0034803271 scopus 로고    scopus 로고
    • Cyclooxygenase-2 stimulates production of amyloid beta-peptide in neuroblastoma x glioma hybrid NG108-15 cells
    • Kadoyama K, Takahashi Y, Higashida H, Tanabe T, and Yoshimoto T (2001) Cyclooxygenase-2 stimulates production of amyloid beta-peptide in neuroblastoma x glioma hybrid NG108-15 cells. Biochem Biophys Res Commun 281:483-490.
    • (2001) Biochem Biophys Res Commun , vol.281 , pp. 483-490
    • Kadoyama, K.1    Takahashi, Y.2    Higashida, H.3    Tanabe, T.4    Yoshimoto, T.5
  • 175
    • 0028920842 scopus 로고
    • Potential involvement of IL-10 in suppressing tumor-associated macrophages. Colon-26-derived prostaglandin E2 inhibits TNF-alpha release via a mechanism involving IL-10
    • Kambayashi T, Alexander HR, Fong M, and Strassmann G (1995) Potential involvement of IL-10 in suppressing tumor-associated macrophages. Colon-26-derived prostaglandin E2 inhibits TNF-alpha release via a mechanism involving IL-10. J Immunol 154:3383-3390.
    • (1995) J Immunol , vol.154 , pp. 3383-3390
    • Kambayashi, T.1    Alexander, H.R.2    Fong, M.3    Strassmann, G.4
  • 176
    • 0029785026 scopus 로고    scopus 로고
    • Expression of COX-2 in human and an animal model of rheumatoid arthritis
    • Kang RY, Freire-Moar J, Sigal E, and Chu CQ (1996) Expression of COX-2 in human and an animal model of rheumatoid arthritis. Br J Rheumatol 35:711-718.
    • (1996) Br J Rheumatol , vol.35 , pp. 711-718
    • Kang, R.Y.1    Freire-Moar, J.2    Sigal, E.3    Chu, C.Q.4
  • 177
    • 0037299903 scopus 로고    scopus 로고
    • Suppression of pro-inflammatory cytokine release by selective inhibition of inducible NO synthase in mucosal explants from patients with ulcerative colitis
    • Kankuri E, Hamalainen M, Hukkanen M, Salmenpera P, Kivilaakso E, Vapaatalo H, and Moilanen E (2003) Suppression of pro-inflammatory cytokine release by selective inhibition of inducible NO synthase in mucosal explants from patients with ulcerative colitis. Scand J Gastroenterol 38:186-192.
    • (2003) Scand J Gastroenterol , vol.38 , pp. 186-192
    • Kankuri, E.1    Hamalainen, M.2    Hukkanen, M.3    Salmenpera, P.4    Kivilaakso, E.5    Vapaatalo, H.6    Moilanen, E.7
  • 178
    • 0034893711 scopus 로고    scopus 로고
    • Suppression of acute experimental colitis by a highly selective inducible nitric-oxide synthase inhibitor, N-[3- (aminomethyl)benzyl]acetamidine
    • Kankuri E, Vaali K, Knowles RG, Lahde M, Korpela R, Vapaatalo H, and Moilanen E (2001) Suppression of acute experimental colitis by a highly selective inducible nitric-oxide synthase inhibitor, N-[3- (aminomethyl)benzyl] acetamidine. J Pharmacol Exp Ther 298:1128-1132.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 1128-1132
    • Kankuri, E.1    Vaali, K.2    Knowles, R.G.3    Lahde, M.4    Korpela, R.5    Vapaatalo, H.6    Moilanen, E.7
  • 179
    • 0029995029 scopus 로고    scopus 로고
    • COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex
    • Kaufmann WE, Worley PF, Pegg J, Bremer M, and Isakson P (1996) COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex. Proc Natl Acad Sci USA 93:2317-2321.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2317-2321
    • Kaufmann, W.E.1    Worley, P.F.2    Pegg, J.3    Bremer, M.4    Isakson, P.5
  • 180
    • 0038547802 scopus 로고    scopus 로고
    • Sepsis alters vessel contraction by adrenoceptor-induced NO and prostanoid
    • Kawabe T, Harris PD, Zakaria EL, and Garrison RN (2003) Sepsis alters vessel contraction by adrenoceptor-induced NO and prostanoid. J Surg Res 110:352-359.
    • (2003) J Surg Res , vol.110 , pp. 352-359
    • Kawabe, T.1    Harris, P.D.2    Zakaria, E.L.3    Garrison, R.N.4
  • 183
    • 0035838273 scopus 로고    scopus 로고
    • Differential roles of cyclooxygenase isoforms after kainic acid-induced prostaglandin E(2) production and neurodegeneration in cortical and hippocampal cell cultures
    • Kim EJ, Lee JE, Kwon KJ, Lee SH, Moon CH, and Baik EJ (2001) Differential roles of cyclooxygenase isoforms after kainic acid-induced prostaglandin E(2) production and neurodegeneration in cortical and hippocampal cell cultures. Brain Res 908: 1-9.
    • (2001) Brain Res , vol.908 , pp. 1-9
    • Kim, E.J.1    Lee, J.E.2    Kwon, K.J.3    Lee, S.H.4    Moon, C.H.5    Baik, E.J.6
  • 184
    • 0035060066 scopus 로고    scopus 로고
    • Expression of c-fos, heat shock protein 70, neurotrophins and cyclooxygenase-2 mRNA in response to focal cerebral ischemia/reperfusion in rats and their modification by magnesium sulfate
    • Kinoshita Y, Ueyama T, Senba E, Terada T, Nakai K, and Itakura T (2001) Expression of c-fos, heat shock protein 70, neurotrophins and cyclooxygenase-2 mRNA in response to focal cerebral ischemia/reperfusion in rats and their modification by magnesium sulfate. J Neurotrauma 18:435-445.
    • (2001) J Neurotrauma , vol.18 , pp. 435-445
    • Kinoshita, Y.1    Ueyama, T.2    Senba, E.3    Terada, T.4    Nakai, K.5    Itakura, T.6
  • 185
    • 0032525118 scopus 로고    scopus 로고
    • Selective expression of inducible NO synthase in human prostate carcinoma
    • Klotz T, Bloch W, Volberg C, Engelmann U, and Addicks K (1998) Selective expression of inducible NO synthase in human prostate carcinoma. Cancer 82:1897-1903.
    • (1998) Cancer , vol.82 , pp. 1897-1903
    • Klotz, T.1    Bloch, W.2    Volberg, C.3    Engelmann, U.4    Addicks, K.5
  • 186
    • 0004452597 scopus 로고    scopus 로고
    • GW273629 is a highly selective, short-acting iNOS (NOS-2) inhibitor both in vitro and in vivo: Beneficial effects in endotoxin shock
    • Portland Press, London
    • Knowles R, Dawson J, Waslidge N, Russell R, Angell A, Craig C, Schwartz S, Evans S, Whittle B, and Garvey E (2000) GW273629 is a highly selective, short-acting iNOS (NOS-2) inhibitor both in vitro and in vivo: beneficial effects in endotoxin shock, in Biology of Nitric Oxide, pp 48-55, vol 7, Portland Press, London.
    • (2000) Biology of Nitric Oxide , vol.7 , pp. 48-55
    • Knowles, R.1    Dawson, J.2    Waslidge, N.3    Russell, R.4    Angell, A.5    Craig, C.6    Schwartz, S.7    Evans, S.8    Whittle, B.9    Garvey, E.10
  • 187
    • 0028349156 scopus 로고
    • NO synthases in mammals
    • Knowles RG and Moncada S (1994) NO synthases in mammals. Biochem J 298:249-258.
    • (1994) Biochem J , vol.298 , pp. 249-258
    • Knowles, R.G.1    Moncada, S.2
  • 188
    • 0037338063 scopus 로고    scopus 로고
    • Effect of the neuronal NO synthase inhibitor 7-nitroindazole on the righting reflex ED50 and minimum alveolar concentration during sevoflurane anaesthesia in rats
    • Kobayashi S, Katoh T, Iwamoto T, Bito H, and Sato S (2003) Effect of the neuronal NO synthase inhibitor 7-nitroindazole on the righting reflex ED50 and minimum alveolar concentration during sevoflurane anaesthesia in rats. Eur J Anaesthesiol 20:212-219.
    • (2003) Eur J Anaesthesiol , vol.20 , pp. 212-219
    • Kobayashi, S.1    Katoh, T.2    Iwamoto, T.3    Bito, H.4    Sato, S.5
  • 190
    • 0028110435 scopus 로고
    • Inhibition of purified NO synthase from rat cerebellum and macrophage by L-arginine analogs
    • Komori Y, Wallace GC, and Fukuto JM (1994) Inhibition of purified NO synthase from rat cerebellum and macrophage by L-arginine analogs. Arch Biochem Biophys 315:213-218.
    • (1994) Arch Biochem Biophys , vol.315 , pp. 213-218
    • Komori, Y.1    Wallace, G.C.2    Fukuto, J.M.3
  • 191
    • 0025357396 scopus 로고
    • Prolongation of fibrinolytic activity of tissue plasminogen activator by nitrovasodilators
    • Korbut R, Lidbury PS, and Vane JR (1990) Prolongation of fibrinolytic activity of tissue plasminogen activator by nitrovasodilators. Lancet 335:669-671.
    • (1990) Lancet , vol.335 , pp. 669-671
    • Korbut, R.1    Lidbury, P.S.2    Vane, J.R.3
  • 192
    • 0026518370 scopus 로고
    • Role of NO in reactive hyperemia of the guinea pig heart
    • Kostic MM and Schrader J (1992) Role of NO in reactive hyperemia of the guinea pig heart. Circ Res 70:208-212.
    • (1992) Circ Res , vol.70 , pp. 208-212
    • Kostic, M.M.1    Schrader, J.2
  • 193
    • 0026612638 scopus 로고
    • Effects of NG-nitro-L-arginine and L-arginine on regional cerebral blood flow in the cat
    • Kovach AG, Szabo C, Benyo Z, Csaki C, Greenberg JH, and Reivich M (1992) Effects of NG-nitro-L-arginine and L-arginine on regional cerebral blood flow in the cat. J Physiol 449:183-196.
    • (1992) J Physiol , vol.449 , pp. 183-196
    • Kovach, A.G.1    Szabo, C.2    Benyo, Z.3    Csaki, C.4    Greenberg, J.H.5    Reivich, M.6
  • 194
    • 0025731835 scopus 로고
    • NO: An endogenous modulator of leukocyte adhesion
    • Kubes P, Suzuki M, and Granger DN (1991) NO: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 88:4651-4655.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4651-4655
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 195
    • 0035133996 scopus 로고    scopus 로고
    • The selective cyclooxygenase-2 inhibitor rofecoxib reduces kainate-induced cell death in the rat hippocampus
    • Kunz T and Oliw EH (2001) The selective cyclooxygenase-2 inhibitor rofecoxib reduces kainate-induced cell death in the rat hippocampus. Eur J Neurosci 13: 569-575.
    • (2001) Eur J Neurosci , vol.13 , pp. 569-575
    • Kunz, T.1    Oliw, E.H.2
  • 197
    • 0025143221 scopus 로고
    • L-Citrulline production from L-arginine by macrophage NO synthase. The ureido oxygen derives from dioxygen
    • Kwon NS, Nathan CF, Gilker C, Griffith OW, Matthews DE, and Stuehr DJ (1990) L-Citrulline production from L-arginine by macrophage NO synthase. The ureido oxygen derives from dioxygen. J Biol Chem 265:13442-13445.
    • (1990) J Biol Chem , vol.265 , pp. 13442-13445
    • Kwon, N.S.1    Nathan, C.F.2    Gilker, C.3    Griffith, O.W.4    Matthews, D.E.5    Stuehr, D.J.6
  • 199
    • 0025117611 scopus 로고
    • EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages
    • Lancaster JR Jr and Hibbs JB Jr (1990) EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages. Proc Natl Acad Sci USA 87:1223-1227.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1223-1227
    • Lancaster Jr., J.R.1    Hibbs Jr., J.B.2
  • 200
    • 0030475604 scopus 로고    scopus 로고
    • Peroxynitrite, the coupling product of NO and superoxide, activates prostaglandin biosynthesis
    • Landino LM, Crews BC, Timmons MD, Morrow JD, and Marnett LJ (1996) Peroxynitrite, the coupling product of NO and superoxide, activates prostaglandin biosynthesis. Proc Natl Acad Sci USA 93:15069-15074.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 15069-15074
    • Landino, L.M.1    Crews, B.C.2    Timmons, M.D.3    Morrow, J.D.4    Marnett, L.J.5
  • 202
    • 0034857232 scopus 로고    scopus 로고
    • Neuroprotection by the selective cyclooxygenase-2 inhibitor SC-236 results in improvements in behavioral deficits induced by reversible spinal cord ischemia
    • Lapchak PA, Araujo DM, Song D, and Zivin JA (2001) Neuroprotection by the selective cyclooxygenase-2 inhibitor SC-236 results in improvements in behavioral deficits induced by reversible spinal cord ischemia. Stroke 32:1220-1225.
    • (2001) Stroke , vol.32 , pp. 1220-1225
    • Lapchak, P.A.1    Araujo, D.M.2    Song, D.3    Zivin, J.A.4
  • 203
    • 0342378148 scopus 로고    scopus 로고
    • Actions of isoform-selective and non-selective NO synthase inhibitors on endotoxin-induced vascular leakage in rat colon
    • Laszlo F and Whittle BJ (1997) Actions of isoform-selective and non-selective NO synthase inhibitors on endotoxin-induced vascular leakage in rat colon. Eur J Pharmacol 334:99-102.
    • (1997) Eur J Pharmacol , vol.334 , pp. 99-102
    • Laszlo, F.1    Whittle, B.J.2
  • 205
    • 0026024563 scopus 로고
    • Captopril-induced reversal of nitroglycerin tolerance: Role of sulfhydryl group vs. ACE-inhibitory activity
    • Lawson DL, Nichols WW, Metha P, and Metha JL (1991) Captopril-induced reversal of nitroglycerin tolerance: role of sulfhydryl group vs. ACE-inhibitory activity. J Cardiovasc Pharmacol 17:411-418.
    • (1991) J Cardiovasc Pharmacol , vol.17 , pp. 411-418
    • Lawson, D.L.1    Nichols, W.W.2    Metha, P.3    Metha, J.L.4
  • 206
    • 10544234611 scopus 로고    scopus 로고
    • The antiplatelet effects of a new nitroderivative of acetylsalicylic acid: An in vitro study of inhibition on early phase of platelet activation and on TXA2 production
    • Lechi C, Andrioli G, Gaino S, Tommasoli R, Zuliani V, Ortolani R, Degan M, Benoni G, Bellavite P, Lechi A, and Minuz P (1996a) The antiplatelet effects of a new nitroderivative of acetylsalicylic acid: an in vitro study of inhibition on early phase of platelet activation and on TXA2 production. Thromb Haemostasis 7:791-798.
    • (1996) Thromb Haemostasis , vol.7 , pp. 791-798
    • Lechi, C.1    Andrioli, G.2    Gaino, S.3    Tommasoli, R.4    Zuliani, V.5    Ortolani, R.6    Degan, M.7    Benoni, G.8    Bellavite, P.9    Lechi, A.10    Minuz, P.11
  • 208
    • 0037446868 scopus 로고    scopus 로고
    • Translational control of inducible NO synthase expression by arginine can explain the arginine paradox
    • Lee J, Ryu H, Ferrante RJ, Morris SM Jr, and Ratan RR (2003) Translational control of inducible NO synthase expression by arginine can explain the arginine paradox. Proc Natl Acad Sci USA 100:4843-4848.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4843-4848
    • Lee, J.1    Ryu, H.2    Ferrante, R.J.3    Morris Jr., S.M.4    Ratan, R.R.5
  • 210
    • 0034528414 scopus 로고    scopus 로고
    • Regulation of APP synthesis and secretion by neuroimmunophilin ligands and cyclooxygenase inhibitors
    • Lee RK and Wurtman RJ (2000) Regulation of APP synthesis and secretion by neuroimmunophilin ligands and cyclooxygenase inhibitors. Ann NY Acad Sci 920:261-268.
    • (2000) Ann NY Acad Sci , vol.920 , pp. 261-268
    • Lee, R.K.1    Wurtman, R.J.2
  • 211
    • 0025045286 scopus 로고
    • Alterations of ribonucleotide reductase activity following induction of the nitrite-generating pathway in adenocarcinoma cells
    • Lepoivre M, Chenais B, Yapo A, Lemaire G, Thelander L, and Tenu JP (1990) Alterations of ribonucleotide reductase activity following induction of the nitrite-generating pathway in adenocarcinoma cells. J Biol Chem 265:14143-14149.
    • (1990) J Biol Chem , vol.265 , pp. 14143-14149
    • Lepoivre, M.1    Chenais, B.2    Yapo, A.3    Lemaire, G.4    Thelander, L.5    Tenu, J.P.6
  • 212
    • 0019499237 scopus 로고
    • Nitroglycerin stimulates synthesis of prostacyclin by cultured human endothelial cells
    • Levine RE, Jaffe EA, Weksler BB, and Tack-Goldman K (1981) Nitroglycerin stimulates synthesis of prostacyclin by cultured human endothelial cells. J Clin Investig 67:762-769.
    • (1981) J Clin Investig , vol.67 , pp. 762-769
    • Levine, R.E.1    Jaffe, E.A.2    Weksler, B.B.3    Tack-Goldman, K.4
  • 213
    • 0028985080 scopus 로고
    • 2 and PGF2 alpha receptors and receptor-coupled second messengers by cyclooxygenase inhibition in newborn pigs
    • 2 and PGF2 alpha receptors and receptor-coupled second messengers by cyclooxygenase inhibition in newborn pigs. J Pharmacol Exp Ther 272:15-19.
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 15-19
    • Li, D.Y.1    Varma, D.R.2    Chemtob, S.3
  • 215
    • 0024313709 scopus 로고
    • Regulation of prostaglandin H synthase mRNA levels and PG biosynthesis by platelet-derived growth factor
    • Lin AH, Bienkowski MJ, and Gorman RR (1989) Regulation of prostaglandin H synthase mRNA levels and PG biosynthesis by platelet-derived growth factor. J Biol Chem 264:17379-17383.
    • (1989) J Biol Chem , vol.264 , pp. 17379-17383
    • Lin, A.H.1    Bienkowski, M.J.2    Gorman, R.R.3
  • 217
    • 33444476617 scopus 로고
    • N-Acetylcysteine potentiates inhibition of platelet aggregation by nitroglycerin
    • Loscalzo J (1981) N-Acetylcysteine potentiates inhibition of platelet aggregation by nitroglycerin. J Clin Investig 67:762-769.
    • (1981) J Clin Investig , vol.67 , pp. 762-769
    • Loscalzo, J.1
  • 218
    • 0025368480 scopus 로고
    • Endothelium-derived vasoactive factors and regulation of vascular tone in human blood vessels
    • Luscher TF (1990) Endothelium-derived vasoactive factors and regulation of vascular tone in human blood vessels. Lung 168 (Suppl):27-34.
    • (1990) Lung , vol.168 , Issue.SUPPL. , pp. 27-34
    • Luscher, T.F.1
  • 220
    • 0028216849 scopus 로고
    • Formation of noncyclooxygenase-derived prostanoids (F2-isoprostanes) in plasma and low density lipoprotein exposed to oxidative stress in vitro
    • Lynch SM, Morrow JD, Roberts LJ 2nd, and Frei B (1994) Formation of noncyclooxygenase-derived prostanoids (F2-isoprostanes) in plasma and low density lipoprotein exposed to oxidative stress in vitro. J Clin Investig 93:998-1004.
    • (1994) J Clin Investig , vol.93 , pp. 998-1004
    • Lynch, S.M.1    Morrow, J.D.2    Roberts II, L.J.3    Frei, B.4
  • 222
    • 0023644747 scopus 로고
    • Quantitative studies of hydroperoxide reduction by prostaglandin H synthase. Reducing substrate specificity and the relationship of peroxidase to COX activities
    • Markey CM, Alward A, Weller PE, and Marnett LJ (1987) Quantitative studies of hydroperoxide reduction by prostaglandin H synthase. Reducing substrate specificity and the relationship of peroxidase to COX activities. J Biol Chem 262:6266-6279.
    • (1987) J Biol Chem , vol.262 , pp. 6266-6279
    • Markey, C.M.1    Alward, A.2    Weller, P.E.3    Marnett, L.J.4
  • 224
    • 0031904583 scopus 로고    scopus 로고
    • Increased inducible activation of NF-kappaB and responsive genes in astrocytes deficient in the protein tyrosine phosphatase SHP-1
    • Massa PT and Wu C (1998) Increased inducible activation of NF-kappaB and responsive genes in astrocytes deficient in the protein tyrosine phosphatase SHP-1. J Interferon Cytokine Res 18:499-507.
    • (1998) J Interferon Cytokine Res , vol.18 , pp. 499-507
    • Massa, P.T.1    Wu, C.2
  • 226
    • 0035693924 scopus 로고    scopus 로고
    • Inflammation, autotoxicity and Alzheimer disease
    • McGeer PL and McGeer EG (2001) Inflammation, autotoxicity and Alzheimer disease. Neurobiol Aging 22:799-809.
    • (2001) Neurobiol Aging , vol.22 , pp. 799-809
    • McGeer, P.L.1    McGeer, E.G.2
  • 228
    • 0028931726 scopus 로고
    • Prokaryotic expression of the heme- and flavin-binding domains of rat neuronal NO synthase as distinct polypeptides: Identification of the heme-binding proximal thiolate ligand as cysteine-415
    • McMillan K and Masters BS (1995) Prokaryotic expression of the heme- and flavin-binding domains of rat neuronal NO synthase as distinct polypeptides: identification of the heme-binding proximal thiolate ligand as cysteine-415. Biochemistry 34:3686-3693.
    • (1995) Biochemistry , vol.34 , pp. 3686-3693
    • McMillan, K.1    Masters, B.S.2
  • 230
    • 0029257415 scopus 로고
    • Identification of constitutive and inducible forms of nitric oxide synthase in human platelets
    • Mehta J, Chen LY, Kone BC, Mehta P, and Turner P (1995) Identification of constitutive and inducible forms of nitric oxide synthase in human platelets. J Lab Clin Med 125:370-377.
    • (1995) J Lab Clin Med , vol.125 , pp. 370-377
    • Mehta, J.1    Chen, L.Y.2    Kone, B.C.3    Mehta, P.4    Turner, P.5
  • 231
    • 0020532125 scopus 로고
    • Effects of nitroglycerin on human vascular prostacyclin and thromboxane A2 generation
    • Mehta J, Mehta P, and Ostrowski N (1993) Effects of nitroglycerin on human vascular prostacyclin and thromboxane A2 generation. J Lab Clin Med 102:116-125.
    • (1993) J Lab Clin Med , vol.102 , pp. 116-125
    • Mehta, J.1    Mehta, P.2    Ostrowski, N.3
  • 232
    • 0020524609 scopus 로고
    • Comparative effects of nitroglycerin and nitroprusside on prostacyclin generation in adult human vessel wall
    • Mehta J, Mehta P, Roberts A, Faro R, Ostrowski N, and Brigmon L (1983) Comparative effects of nitroglycerin and nitroprusside on prostacyclin generation in adult human vessel wall. J Am Coll Cardiol 2:625-630.
    • (1983) J Am Coll Cardiol , vol.2 , pp. 625-630
    • Mehta, J.1    Mehta, P.2    Roberts, A.3    Faro, R.4    Ostrowski, N.5    Brigmon, L.6
  • 233
    • 0023855416 scopus 로고
    • Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (COX)
    • Merlie JP, Fagan D, Mudd J, and Needleman P (1988) Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (COX). J Biol Chem 263:3550-3553.
    • (1988) J Biol Chem , vol.263 , pp. 3550-3553
    • Merlie, J.P.1    Fagan, D.2    Mudd, J.3    Needleman, P.4
  • 234
    • 0041519221 scopus 로고    scopus 로고
    • Inhibitors of the NOS enzymes: A patent review
    • Mete A and Connolly S (2003) Inhibitors of the NOS enzymes: a patent review. Drugs 6:57-65.
    • (2003) Drugs , vol.6 , pp. 57-65
    • Mete, A.1    Connolly, S.2
  • 235
    • 0031985513 scopus 로고    scopus 로고
    • Microglia as effector cells in brain damage and repair: Focus on prostanoids and nitric oxide
    • Minghetti L and Levi G (1998) Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide. Prog Neurobiol 54:99-125.
    • (1998) Prog Neurobiol , vol.54 , pp. 99-125
    • Minghetti, L.1    Levi, G.2
  • 236
    • 0031283513 scopus 로고    scopus 로고
    • Prostaglandin E2 downregulates inducible nitric oxide synthase expression in microglia by increasing cAMP levels
    • Minghetti L, Nicolini A, Polazzi E, Creminon C, Maclouf J, and Levi G (1997a) Prostaglandin E2 downregulates inducible nitric oxide synthase expression in microglia by increasing cAMP levels. Adv Exp Med Biol 433:181-184.
    • (1997) Adv Exp Med Biol , vol.433 , pp. 181-184
    • Minghetti, L.1    Nicolini, A.2    Polazzi, E.3    Creminon, C.4    Maclouf, J.5    Levi, G.6
  • 237
    • 0029961125 scopus 로고    scopus 로고
    • Interferon-gamma and nitric oxide down-regulate lipopolysaccharide- induced prostanoid production in cultured rat microglial cells by inhibiting cyclooxygenase-2 expression
    • Minghetti L, Polazzi E, Nicolini A, Creminon C, and Levi G (1996) Interferon-gamma and nitric oxide down-regulate lipopolysaccharide-induced prostanoid production in cultured rat microglial cells by inhibiting cyclooxygenase-2 expression. J Neurochem 66:1963-1970.
    • (1996) J Neurochem , vol.66 , pp. 1963-1970
    • Minghetti, L.1    Polazzi, E.2    Nicolini, A.3    Creminon, C.4    Levi, G.5
  • 238
    • 0030994412 scopus 로고    scopus 로고
    • Up-regulation of cyclooxygenase-2 expression in cultured microglia by prostaglandin E2, cyclic AMP and non-steroidal anti-inflammatory drugs
    • Minghetti L, Polazzi E, Nicolini A, Creminon C, and Levi G (1997b) Up-regulation of cyclooxygenase-2 expression in cultured microglia by prostaglandin E2, cyclic AMP and non-steroidal anti-inflammatory drugs. Eur J Neurosci 9:934-940.
    • (1997) Eur J Neurosci , vol.9 , pp. 934-940
    • Minghetti, L.1    Polazzi, E.2    Nicolini, A.3    Creminon, C.4    Levi, G.5
  • 240
    • 0031874813 scopus 로고    scopus 로고
    • NO aspirins: Antithrombotic activity of derivatives of acetylsalicylic acid releasing nitric oxide
    • Minuz P, Lechi C, and Zuliani V (1998) NO aspirins: antithrombotic activity of derivatives of acetylsalicylic acid releasing nitric oxide. Cardiovasc Drug Rev 16:31-47.
    • (1998) Cardiovasc Drug Rev , vol.16 , pp. 31-47
    • Minuz, P.1    Lechi, C.2    Zuliani, V.3
  • 242
    • 0028792386 scopus 로고
    • Mediation of inflammation by encephalitogenic cells: Interferon gamma induction of NO synthase and COX 2
    • Misko TP, Trotter JL, and Cross AH (1995) Mediation of inflammation by encephalitogenic cells: interferon gamma induction of NO synthase and COX 2. J Neuroimmunol 61:195-204.
    • (1995) J Neuroimmunol , vol.61 , pp. 195-204
    • Misko, T.P.1    Trotter, J.L.2    Cross, A.H.3
  • 244
  • 245
    • 0032737556 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2: Pharmacology, physiology, biochemistry and relevance to NSAID therapy
    • Mitchell JA and Warner TD (1999) Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy. Br J Pharmacol 128:1121-1132.
    • (1999) Br J Pharmacol , vol.128 , pp. 1121-1132
    • Mitchell, J.A.1    Warner, T.D.2
  • 246
    • 0018134378 scopus 로고
    • Plasma prostaglandin levels during early neonatal life following term and pre-term delivery
    • Mitchell MD, Lucas A, Etches PC, Brunt JD, and Turnbull AC (1978) Plasma prostaglandin levels during early neonatal life following term and pre-term delivery. Prostaglandins 16:319-326.
    • (1978) Prostaglandins , vol.16 , pp. 319-326
    • Mitchell, M.D.1    Lucas, A.2    Etches, P.C.3    Brunt, J.D.4    Turnbull, A.C.5
  • 247
    • 0017070560 scopus 로고
    • Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes
    • Miyamoto T, Ogino N, Yamamoto S, and Hayaishi O (1976) Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes. J Biol Chem 251:2629-2636.
    • (1976) J Biol Chem , vol.251 , pp. 2629-2636
    • Miyamoto, T.1    Ogino, N.2    Yamamoto, S.3    Hayaishi, O.4
  • 248
    • 0031052116 scopus 로고    scopus 로고
    • Induction of COX 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice
    • Mizuno H, Sakamoto C, Matsuda K, Wada K, Uchida T, Noguchi H, Akamatsu T, and Kasuga M (1997) Induction of COX 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice. Gastroenterology 112:387-397.
    • (1997) Gastroenterology , vol.112 , pp. 387-397
    • Mizuno, H.1    Sakamoto, C.2    Matsuda, K.3    Wada, K.4    Uchida, T.5    Noguchi, H.6    Akamatsu, T.7    Kasuga, M.8
  • 251
    • 0028167677 scopus 로고
    • HIV coating gp 120 glycoprotein-dependent prostaglandin E2 release by human cultured astrocytoma cells is regulated by nitric oxide formation
    • Mollace V, Colasanti M, Rodino P, Lauro GM, and Nistico G (1994) HIV coating gp 120 glycoprotein-dependent prostaglandin E2 release by human cultured astrocytoma cells is regulated by nitric oxide formation. Biochem Biophys Res Commun 203:87-92.
    • (1994) Biochem Biophys Res Commun , vol.203 , pp. 87-92
    • Mollace, V.1    Colasanti, M.2    Rodino, P.3    Lauro, G.M.4    Nistico, G.5
  • 253
    • 0031590261 scopus 로고    scopus 로고
    • Spontaneous induction of nitric oxide- and prostaglandin E2-release by hypoxic astroglial cells is modulated by interleukin 1 beta
    • Mollace V, Muscoli C, Rotiroti D, and Nistico G (1997) Spontaneous induction of nitric oxide- and prostaglandin E2-release by hypoxic astroglial cells is modulated by interleukin 1 beta. Biochem Biophys Res Commun 238:916-919.
    • (1997) Biochem Biophys Res Commun , vol.238 , pp. 916-919
    • Mollace, V.1    Muscoli, C.2    Rotiroti, D.3    Nistico, G.4
  • 254
    • 0026341692 scopus 로고
    • Studies on the importance of the proposed L-arginine to nitric oxide pathway in platelets
    • Mollace V, Salvemini D, and Vane JR (1991) Studies on the importance of the proposed L-arginine to nitric oxide pathway in platelets. Thromb Res 64:533-542.
    • (1991) Thromb Res , vol.64 , pp. 533-542
    • Mollace, V.1    Salvemini, D.2    Vane, J.R.3
  • 255
    • 0017094798 scopus 로고
    • An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
    • Moncada S, Gryglewski R, Bunting S, and Vane JR (1976) An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation. Nature (Lond) 263:663-665.
    • (1976) Nature (Lond) , vol.263 , pp. 663-665
    • Moncada, S.1    Gryglewski, R.2    Bunting, S.3    Vane, J.R.4
  • 256
    • 0028863627 scopus 로고
    • Molecular mechanisms and therapeutic strategies related to NO
    • Moncada S and Higgs EA (1995) Molecular mechanisms and therapeutic strategies related to NO. FASEB J 9:1319-1330.
    • (1995) FASEB J , vol.9 , pp. 1319-1330
    • Moncada, S.1    Higgs, E.A.2
  • 257
    • 0026022371 scopus 로고
    • Inhibition of the induction of NO synthase by glucocorticoids: Yet another explanation for their anti-inflammatory effects?
    • Moncada S and Palmer RM (1991) Inhibition of the induction of NO synthase by glucocorticoids: yet another explanation for their anti-inflammatory effects? Trends Pharmacol Sci 12:130-131.
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 130-131
    • Moncada, S.1    Palmer, R.M.2
  • 258
    • 0028990886 scopus 로고
    • Formation of F2-isoprostanes during oxidation of human low-density lipoprotein and plasma by peroxynitrite
    • Moore KP, Darley-Usmar V, Morrow J, and Roberts LJ 2nd (1995) Formation of F2-isoprostanes during oxidation of human low-density lipoprotein and plasma by peroxynitrite. Circ Res 77:335-341.
    • (1995) Circ Res , vol.77 , pp. 335-341
    • Moore, K.P.1    Darley-Usmar, V.2    Morrow, J.3    Roberts II, L.J.4
  • 261
    • 0018223989 scopus 로고
    • Mechanism of enhanced renal PG biosynthesis in ureter obstruction. Role of de novo protein synthesis
    • Morrison AR, Moritz H, and Needleman P (1978) Mechanism of enhanced renal PG biosynthesis in ureter obstruction. Role of de novo protein synthesis. J Biol Chem 253:8210-8212.
    • (1978) J Biol Chem , vol.253 , pp. 8210-8212
    • Morrison, A.R.1    Moritz, H.2    Needleman, P.3
  • 262
    • 0032795598 scopus 로고    scopus 로고
    • Analgesic efficacy of the COX-2-specific inhibitor rofecoxib in post-dental surgery pain: A randomized, controlled trial
    • Morrison BW, Christensen S, Yuan W, Brown J, Amlani S, and Seidenberg B (1999) Analgesic efficacy of the COX-2-specific inhibitor rofecoxib in post-dental surgery pain: a randomized, controlled trial. Clin Ther 21:943-953.
    • (1999) Clin Ther , vol.21 , pp. 943-953
    • Morrison, B.W.1    Christensen, S.2    Yuan, W.3    Brown, J.4    Amlani, S.5    Seidenberg, B.6
  • 264
    • 0035383764 scopus 로고    scopus 로고
    • In vivo and in vitro apoptosis of human thymocytes are associated with nitrotyrosine formation
    • Moulian N, Truffault F, Gaudry-Talarmain YM, Serraf A, and Berrih-Aknin S (2001) In vivo and in vitro apoptosis of human thymocytes are associated with nitrotyrosine formation. Blood 97:3521-3530.
    • (2001) Blood , vol.97 , pp. 3521-3530
    • Moulian, N.1    Truffault, F.2    Gaudry-Talarmain, Y.M.3    Serraf, A.4    Berrih-Aknin, S.5
  • 268
    • 0034573493 scopus 로고    scopus 로고
    • Molecular aspects of the expression and regulation of endothelial NO synthase
    • Nadaud S, Laumonnier Y, and Soubrier F (2000) Molecular aspects of the expression and regulation of endothelial NO synthase. J Soc Biol 194:131-135.
    • (2000) J Soc Biol , vol.194 , pp. 131-135
    • Nadaud, S.1    Laumonnier, Y.2    Soubrier, F.3
  • 269
    • 0031714239 scopus 로고    scopus 로고
    • Delayed treatment with aminoguanidine decreases focal cerebral ischemic damage and enhances neurologic recovery in rats
    • Nagayama M, Zhang F, and Iadecola C (1998) Delayed treatment with aminoguanidine decreases focal cerebral ischemic damage and enhances neurologic recovery in rats. J Cereb Blood Flow Metab 18:1107-1113.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 1107-1113
    • Nagayama, M.1    Zhang, F.2    Iadecola, C.3
  • 271
    • 0027473029 scopus 로고
    • Cloned human brain NO synthase is highly expressed in skeletal muscle
    • Nakane M, Schmidt HH, Pollock JS, Forstermann U, and Murad F (1993) Cloned human brain NO synthase is highly expressed in skeletal muscle. FEBS Lett 316:175-180.
    • (1993) FEBS Lett , vol.316 , pp. 175-180
    • Nakane, M.1    Schmidt, H.H.2    Pollock, J.S.3    Forstermann, U.4    Murad, F.5
  • 272
    • 0030457643 scopus 로고    scopus 로고
    • Effects of nimesulide, a preferential COX-2 inhibitor, on carrageenan-induced pleurisy and stress-induced gastric lesions in rats
    • Nakatsugi S, Terada N, Yoshimura T, Horie Y, and Furukawa M (1996) Effects of nimesulide, a preferential COX-2 inhibitor, on carrageenan-induced pleurisy and stress-induced gastric lesions in rats. Prostaglandins Leukotrienes Essent Fatty Acids 55:395-402.
    • (1996) Prostaglandins Leukotrienes Essent Fatty Acids , vol.55 , pp. 395-402
    • Nakatsugi, S.1    Terada, N.2    Yoshimura, T.3    Horie, Y.4    Furukawa, M.5
  • 276
    • 0026629902 scopus 로고
    • NO as a secretory product of mammalian cells
    • Nathan C (1992) NO as a secretory product of mammalian cells. FASEB J 6:3051-3064.
    • (1992) FASEB J , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 277
    • 0028092958 scopus 로고
    • NO synthases: Roles, tolls and controls
    • Nathan C and Xie QW (1994) NO synthases: roles, tolls and controls. Cell 78:915-918.
    • (1994) Cell , vol.78 , pp. 915-918
    • Nathan, C.1    Xie, Q.W.2
  • 278
    • 0015595425 scopus 로고
    • Mechanism of tolerance development to organic nitrates
    • Needleman P and Johnson EM (1973) Mechanism of tolerance development to organic nitrates. J Pharmacol Exp Ther 184:709-715.
    • (1973) J Pharmacol Exp Ther , vol.184 , pp. 709-715
    • Needleman, P.1    Johnson, E.M.2
  • 279
    • 0033166188 scopus 로고    scopus 로고
    • Interactions between the inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) pathways: Implications for therapeutic intervention in osteoarthritis
    • Needleman P and Manning PT (1999) Interactions between the inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) pathways: implications for therapeutic intervention in osteoarthritis. Osteoarthritis Cartilage 7:367-370.
    • (1999) Osteoarthritis Cartilage , vol.7 , pp. 367-370
    • Needleman, P.1    Manning, P.T.2
  • 281
    • 0032780043 scopus 로고    scopus 로고
    • COX-2-dependent arachidonic acid metabolites are essential modulators of the intestinal immune response to dietary antigen
    • Newberry RD, Stenson WF, and Lorenz RG (1999) COX-2-dependent arachidonic acid metabolites are essential modulators of the intestinal immune response to dietary antigen. Nat Med 5:900-906.
    • (1999) Nat Med , vol.5 , pp. 900-906
    • Newberry, R.D.1    Stenson, W.F.2    Lorenz, R.G.3
  • 282
    • 0029826422 scopus 로고    scopus 로고
    • Inhibition of diamine oxidase promotes uptake of putrescine from rat small intestine
    • Nilsson BO, Kockum I, and Rosengren E (1996) Inhibition of diamine oxidase promotes uptake of putrescine from rat small intestine. Inflamm Res 45:513-518.
    • (1996) Inflamm Res , vol.45 , pp. 513-518
    • Nilsson, B.O.1    Kockum, I.2    Rosengren, E.3
  • 284
    • 0030909616 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage
    • Nogawa S, Zhang F, Ross ME, and Iadecola C (1997) Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage. J Neurosci 17:2746-2755.
    • (1997) J Neurosci , vol.17 , pp. 2746-2755
    • Nogawa, S.1    Zhang, F.2    Ross, M.E.3    Iadecola, C.4
  • 285
    • 0034665322 scopus 로고    scopus 로고
    • The induction of cell death in human osteoarthritis chondrocytes by NO is related to the production of prostaglandin E2 via the induction of COX-2
    • Notoya K, Jovanovic DV, Reboul P, Martel-Pelletier J, Mineau F, and Pelletier JP (2000) The induction of cell death in human osteoarthritis chondrocytes by NO is related to the production of prostaglandin E2 via the induction of COX-2. J Immunol 165:3402-3410.
    • (2000) J Immunol , vol.165 , pp. 3402-3410
    • Notoya, K.1    Jovanovic, D.V.2    Reboul, P.3    Martel-Pelletier, J.4    Mineau, F.5    Pelletier, J.P.6
  • 286
    • 0027244724 scopus 로고
    • Inflammation, immunoregulation and inducible NO synthase
    • Nussler AK and Billiar TR (1993) Inflammation, immunoregulation and inducible NO synthase. J Leukoc Biol 54:171-178.
    • (1993) J Leukoc Biol , vol.54 , pp. 171-178
    • Nussler, A.K.1    Billiar, T.R.2
  • 287
    • 0029953089 scopus 로고    scopus 로고
    • Interleukin-1 beta induces prostaglandin G/H synthase-2 (cyclooxygenase-2) in primary murine astrocyte cultures
    • O'Banion MK, Miller JC, Chang JW, Kaplan MD, and Coleman PD (1996) Interleukin-1 beta induces prostaglandin G/H synthase-2 (cyclooxygenase-2) in primary murine astrocyte cultures. J Neurochem 66:2532-2540.
    • (1996) J Neurochem , vol.66 , pp. 2532-2540
    • O'Banion, M.K.1    Miller, J.C.2    Chang, J.W.3    Kaplan, M.D.4    Coleman, P.D.5
  • 288
    • 0026322957 scopus 로고
    • A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a COX-related protein
    • O'Banion MK, Sadowski HB, Winn V, and Young DA (1991) A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a COX-related protein. J Biol Chem 266:23261-23267.
    • (1991) J Biol Chem , vol.266 , pp. 23261-23267
    • O'Banion, M.K.1    Sadowski, H.B.2    Winn, V.3    Young, D.A.4
  • 289
    • 0028784784 scopus 로고
    • In situ hybridization studies of prostacyclin receptor mRNA expression in various mouse organs
    • Oida H, Namba T, Sugimoto Y, Ushikubi F, Ohishi H, Ichikawa A, and Narumiya S (1995) In situ hybridization studies of prostacyclin receptor mRNA expression in various mouse organs. Br J Pharmacol 116:2828-2837.
    • (1995) Br J Pharmacol , vol.116 , pp. 2828-2837
    • Oida, H.1    Namba, T.2    Sugimoto, Y.3    Ushikubi, F.4    Ohishi, H.5    Ichikawa, A.6    Narumiya, S.7
  • 290
    • 0026575878 scopus 로고
    • Effect of acetylcholine on the highly stenotic coronary artery: Difference between the constrictor response of the infarct-related coronary artery and that of the noninfarct-related artery
    • Okumura K, Yasue H, Matsuyama K, Ogawa H, Morikami Y, Obata K, and Sakaino N (1992) Effect of acetylcholine on the highly stenotic coronary artery: difference between the constrictor response of the infarct-related coronary artery and that of the noninfarct-related artery. J Am Coll Cardiol 19:753-758.
    • (1992) J Am Coll Cardiol , vol.19 , pp. 753-758
    • Okumura, K.1    Yasue, H.2    Matsuyama, K.3    Ogawa, H.4    Morikami, Y.5    Obata, K.6    Sakaino, N.7
  • 292
    • 0028842742 scopus 로고
    • Prostaglandin endoperoxide synthases-1 and -2
    • Otto JC and Smith WL (1995) Prostaglandin endoperoxide synthases-1 and -2. J Lipid Mediat Cell Signal 12:139-156.
    • (1995) J Lipid Mediat Cell Signal , vol.12 , pp. 139-156
    • Otto, J.C.1    Smith, W.L.2
  • 293
    • 0027517899 scopus 로고
    • Aminoguanidine: A drug proposed for prophylaxis in diabetes inhibits catalase and generates hydrogen peroxide in vitro
    • Ou P and Wolff SP (1993) Aminoguanidine: a drug proposed for prophylaxis in diabetes inhibits catalase and generates hydrogen peroxide in vitro. Biochem Pharmacol 46:1139-1144.
    • (1993) Biochem Pharmacol , vol.46 , pp. 1139-1144
    • Ou, P.1    Wolff, S.P.2
  • 294
    • 0023198721 scopus 로고
    • NO release accounts for the biological activity of endothelium-derived relaxing factor
    • Palmer RM, Ferrige AG, and Moncada S (1987) NO release accounts for the biological activity of endothelium-derived relaxing factor. Nature (Lond) 327:524-526.
    • (1987) Nature (Lond) , vol.327 , pp. 524-526
    • Palmer, R.M.1    Ferrige, A.G.2    Moncada, S.3
  • 295
    • 0032512822 scopus 로고    scopus 로고
    • Nitric oxide is an upstream signal of vascular endothelial growth factor-induced extracellular signal-regulated kinase1/2 activation in postcapillary endothelium
    • Parenti A, Morbidelli L, Cui XL, Douglas JG, Hood JD, Granger HJ, Ledda F, and Ziche M (1998) Nitric oxide is an upstream signal of vascular endothelial growth factor-induced extracellular signal-regulated kinase1/2 activation in postcapillary endothelium. J Biol Chem 273:4220-4226.
    • (1998) J Biol Chem , vol.273 , pp. 4220-4226
    • Parenti, A.1    Morbidelli, L.2    Cui, X.L.3    Douglas, J.G.4    Hood, J.D.5    Granger, H.J.6    Ledda, F.7    Ziche, M.8
  • 296
    • 0034117970 scopus 로고    scopus 로고
    • Developmental changes in endothelium-derived vasorelaxant factors in cerebral circulation
    • Parfenova H, Massie V, and Leffler CW (2000) Developmental changes in endothelium-derived vasorelaxant factors in cerebral circulation. Am J Physiol Heart Circ Physiol 278:H780-H788.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Parfenova, H.1    Massie, V.2    Leffler, C.W.3
  • 297
    • 0023664555 scopus 로고
    • Nitrate therapy in stable angina pectoris
    • Parker JO (1987) Nitrate therapy in stable angina pectoris. N Engl J Med 316:1635-1642.
    • (1987) N Engl J Med , vol.316 , pp. 1635-1642
    • Parker, J.O.1
  • 298
    • 0023250954 scopus 로고
    • Determinants of drug response in severe chronic heart failure. Activation of vasoconstrictor forced during vasodilator therapy
    • Parker JO, Farrell B, Lahey KA, and Rose BF (1987) Determinants of drug response in severe chronic heart failure. Activation of vasoconstrictor forced during vasodilator therapy. Circulation 76:572-576.
    • (1987) Circulation , vol.76 , pp. 572-576
    • Parker, J.O.1    Farrell, B.2    Lahey, K.A.3    Rose, B.F.4
  • 299
    • 0021235248 scopus 로고
    • Transdermal nitroglycerin in angina pectoris
    • Parker JO and Fung HL (1984) Transdermal nitroglycerin in angina pectoris. Am J Cardiol 54:471-476.
    • (1984) Am J Cardiol , vol.54 , pp. 471-476
    • Parker, J.O.1    Fung, H.L.2
  • 300
    • 0034924557 scopus 로고    scopus 로고
    • Cyclooxygenase and Alzheimer's disease: Implications for preventive initiatives to slow the progression of clinical dementia
    • Pasinetti GM (2001) Cyclooxygenase and Alzheimer's disease: implications for preventive initiatives to slow the progression of clinical dementia. Arch Gerontol Geriatr 33:13-28.
    • (2001) Arch Gerontol Geriatr , vol.33 , pp. 13-28
    • Pasinetti, G.M.1
  • 302
    • 0029011129 scopus 로고
    • Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B
    • Peng HB, Libby P, and Liao JK (1995) Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B. J Biol Chem 270:14214-14219.
    • (1995) J Biol Chem , vol.270 , pp. 14214-14219
    • Peng, H.B.1    Libby, P.2    Liao, J.K.3
  • 303
    • 0033637536 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 expression during HIV-1-infected monocyte-derived macrophage and human brain microvascular endothelial cell interactions
    • Pereira CF, Boven LA, Middel J, Verhoef J, and Nottet HS (2000) Induction of cyclooxygenase-2 expression during HIV-1-infected monocyte-derived macrophage and human brain microvascular endothelial cell interactions. J Leukoc Biol 68:423-428.
    • (2000) J Leukoc Biol , vol.68 , pp. 423-428
    • Pereira, C.F.1    Boven, L.A.2    Middel, J.3    Verhoef, J.4    Nottet, H.S.5
  • 304
    • 0028822708 scopus 로고
    • Prostaglandin G/H synthase-2 is a major contributor of brain prostaglandins in the newborn
    • Peri KG, Hardy P, Li DY, Varma DR, and Chemtob S (1995) Prostaglandin G/H synthase-2 is a major contributor of brain prostaglandins in the newborn. J Biol Chem 270:24615-24620.
    • (1995) J Biol Chem , vol.270 , pp. 24615-24620
    • Peri, K.G.1    Hardy, P.2    Li, D.Y.3    Varma, D.R.4    Chemtob, S.5
  • 306
    • 0029888810 scopus 로고    scopus 로고
    • Inhibition of NO synthesis by NG-nitro-L-arginine methyl ester (L-NAME): Requirement for bioactivation to the free acid, NG-nitro-L-arginine
    • Pfeiffer S, Leopold E, Schmidt K, Brunner F, and Mayer B (1996) Inhibition of NO synthesis by NG-nitro-L-arginine methyl ester (L-NAME): requirement for bioactivation to the free acid, NG-nitro-L-arginine. Br J Pharmacol 118:1433-1440.
    • (1996) Br J Pharmacol , vol.118 , pp. 1433-1440
    • Pfeiffer, S.1    Leopold, E.2    Schmidt, K.3    Brunner, F.4    Mayer, B.5
  • 307
    • 0028009093 scopus 로고
    • The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
    • Picot D, Loll PJ, and Garavito RM (1994) The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1. Nature (Lond) 367:243-249.
    • (1994) Nature (Lond) , vol.367 , pp. 243-249
    • Picot, D.1    Loll, P.J.2    Garavito, R.M.3
  • 308
    • 0028234842 scopus 로고
    • Nitroblue tetrazolium inhibits the metabolism of glyceryl trinitrate to nitric oxide in bovine aortic smooth muscle cells
    • Pistelli A, Mollace V, Anggard E, Salvemini D, and Vane J (1994) Nitroblue tetrazolium inhibits the metabolism of glyceryl trinitrate to nitric oxide in bovine aortic smooth muscle cells. Biochem Pharmacol 47:1737-1742.
    • (1994) Biochem Pharmacol , vol.47 , pp. 1737-1742
    • Pistelli, A.1    Mollace, V.2    Anggard, E.3    Salvemini, D.4    Vane, J.5
  • 309
    • 0036460608 scopus 로고    scopus 로고
    • Second phase of formalin-induced excitation of spinal dorsal horn neurons in spinalized rats is reversed by sciatic nerve block
    • Pitcher GM and Henry JL (2002) Second phase of formalin-induced excitation of spinal dorsal horn neurons in spinalized rats is reversed by sciatic nerve block. Eur J Neurosci 15:1509-1515.
    • (2002) Eur J Neurosci , vol.15 , pp. 1509-1515
    • Pitcher, G.M.1    Henry, J.L.2
  • 310
    • 0022590909 scopus 로고
    • Crucial role of endothelium in the vasodilator response to increased flow in vivo
    • Pohl U, Holtz J, Busse R, and Bassenge E (1986) Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension 8:37-44.
    • (1986) Hypertension , vol.8 , pp. 37-44
    • Pohl, U.1    Holtz, J.2    Busse, R.3    Bassenge, E.4
  • 311
    • 0023960283 scopus 로고
    • Cytochrome P450: Molecular architecture, mechanism and prospects for rational inhibitor design
    • Poulos TL (1988) Cytochrome P450: molecular architecture, mechanism and prospects for rational inhibitor design (Review). Pharm Res (NY) 5:67-75.
    • (1988) Pharm Res (NY) , vol.5 , pp. 67-75
    • Poulos, T.L.1
  • 312
    • 0025874048 scopus 로고
    • Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and NO
    • Radi R, Beckman JS, Bush KM, and Freeman BA (1991) Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and NO. Arch Biochem Biophys 288:481-487.
    • (1991) Arch Biochem Biophys , vol.288 , pp. 481-487
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3    Freeman, B.A.4
  • 313
    • 0023446425 scopus 로고
    • The anti-aggregating properties of vascular endothelium: Interactions between prostacyclin and NO
    • Radomski MW, Palmer RM, and Moncada S (1987) The anti-aggregating properties of vascular endothelium: interactions between prostacyclin and NO. Br J Pharmacol 92:639-646.
    • (1987) Br J Pharmacol , vol.92 , pp. 639-646
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 314
    • 0024528921 scopus 로고
    • A specific inhibitor of NO formation from L-arginine attenuates endothelium-dependent relaxation
    • Rees DD, Palmer RM, Hodson HF, and Moncada S (1989a) A specific inhibitor of NO formation from L-arginine attenuates endothelium-dependent relaxation. Br J Pharmacol 96:418-424.
    • (1989) Br J Pharmacol , vol.96 , pp. 418-424
    • Rees, D.D.1    Palmer, R.M.2    Hodson, H.F.3    Moncada, S.4
  • 315
    • 0001599370 scopus 로고
    • Role of endothelium-derived NO in the regulation of blood pressure
    • Rees DD, Palmer RM, and Moncada S (1989b) Role of endothelium-derived NO in the regulation of blood pressure. Proc Natl Acad Sci USA 86:3375-3378.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3375-3378
    • Rees, D.D.1    Palmer, R.M.2    Moncada, S.3
  • 316
    • 0025011716 scopus 로고
    • Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo
    • Rees DD, Palmer RM, Schulz R, Hodson HF, and Moncada S (1990) Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br J Pharmacol 101:746-752.
    • (1990) Br J Pharmacol , vol.101 , pp. 746-752
    • Rees, D.D.1    Palmer, R.M.2    Schulz, R.3    Hodson, H.F.4    Moncada, S.5
  • 317
    • 0026782496 scopus 로고
    • Chronic inhibition of NO synthesis. A new model of arterial hypertension
    • Ribeiro MO, Antunes E, De Nucci G, Lovisolo SM, and Zatz R (1992) Chronic inhibition of NO synthesis. A new model of arterial hypertension. Hypertension 20:298-303.
    • (1992) Hypertension , vol.20 , pp. 298-303
    • Ribeiro, M.O.1    Antunes, E.2    De Nucci, G.3    Lovisolo, S.M.4    Zatz, R.5
  • 322
    • 0034992403 scopus 로고    scopus 로고
    • Regulation of prostacyclin and prostaglandin E(2) receptor mediated responses in adult rat dorsal root ganglion cells, in vitro
    • Rowlands DK, Kao C, and Wise H (2001) Regulation of prostacyclin and prostaglandin E(2) receptor mediated responses in adult rat dorsal root ganglion cells, in vitro. Br J Pharmacol 133:13-22.
    • (2001) Br J Pharmacol , vol.133 , pp. 13-22
    • Rowlands, D.K.1    Kao, C.2    Wise, H.3
  • 323
    • 0022516979 scopus 로고
    • Flow-induced release of endothelium-derived relaxing factor
    • Rubanyi GM, Romero JC, and Vanhoutte PM (1986) Flow-induced release of endothelium-derived relaxing factor. Am J Physiol 250:H1145-H1149.
    • (1986) Am J Physiol , vol.250
    • Rubanyi, G.M.1    Romero, J.C.2    Vanhoutte, P.M.3
  • 324
    • 0037401028 scopus 로고    scopus 로고
    • Different tumors in bone each give rise to a distinct pattern of skeletal destruction, bone cancer-related pain behaviors and neurochemical changes in the central nervous system
    • Sabino MA, Luger NM, Mach DB, Rogers SD, Schwei MJ, and Mantyh PW (2003) Different tumors in bone each give rise to a distinct pattern of skeletal destruction, bone cancer-related pain behaviors and neurochemical changes in the central nervous system. Int J Cancer 104:550-558.
    • (2003) Int J Cancer , vol.104 , pp. 550-558
    • Sabino, M.A.1    Luger, N.M.2    Mach, D.B.3    Rogers, S.D.4    Schwei, M.J.5    Mantyh, P.W.6
  • 325
    • 0029894331 scopus 로고    scopus 로고
    • Nitric oxide-mediated cyclooxygenase activation. A key event in the antiplatelet effects of nitrovasodilators
    • Salvemini D, Currie MG, and Mollace V (1996) Nitric oxide-mediated cyclooxygenase activation. A key event in the antiplatelet effects of nitrovasodilators. J Clin Investig 97:2562-2568.
    • (1996) J Clin Investig , vol.97 , pp. 2562-2568
    • Salvemini, D.1    Currie, M.G.2    Mollace, V.3
  • 326
    • 0025275075 scopus 로고
    • Immediate release of a NO-like factor from bovine aortic endothelial cells by Escherichia coli lipopolysaccharide
    • Salvemini D, Korbut R, Anggard E, and Vane J (1990a) Immediate release of a NO-like factor from bovine aortic endothelial cells by Escherichia coli lipopolysaccharide. Proc Natl Acad Sci USA 87:2593-2597.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2593-2597
    • Salvemini, D.1    Korbut, R.2    Anggard, E.3    Vane, J.4
  • 327
    • 0024404929 scopus 로고
    • Lipopolysaccharide increases release of a NO-like factor from endothelial cells
    • Salvemini D, Korbut R, Anggard E, and Vane JR (1989) Lipopolysaccharide increases release of a NO-like factor from endothelial cells. Eur J Pharmacol 171:135-136.
    • (1989) Eur J Pharmacol , vol.171 , pp. 135-136
    • Salvemini, D.1    Korbut, R.2    Anggard, E.3    Vane, J.R.4
  • 328
    • 0029160559 scopus 로고
    • Dual inhibition of nitric oxide and prostaglandin contribute to the anti-inflammatory properties of nitric oxide synthase inhibitors
    • Salvemini D, Manning PT, Zweifel B, Seibert K, Currie MG, Needleman P, and Masferrer JL (1995a) Dual inhibition of nitric oxide and prostaglandin contribute to the anti-inflammatory properties of nitric oxide synthase inhibitors. J Clin Investig 96:301-308.
    • (1995) J Clin Investig , vol.96 , pp. 301-308
    • Salvemini, D.1    Manning, P.T.2    Zweifel, B.3    Seibert, K.4    Currie, M.G.5    Needleman, P.6    Masferrer, J.L.7
  • 329
    • 0029793809 scopus 로고    scopus 로고
    • Interactions of nitric oxide with cyclooxygenase: In vitro, ex vivo and in vivo studies
    • Salvemini D and Masferrer JL (1996) Interactions of nitric oxide with cyclooxygenase: in vitro, ex vivo and in vivo studies. Methods Enzymol 269:12-25.
    • (1996) Methods Enzymol , vol.269 , pp. 12-25
    • Salvemini, D.1    Masferrer, J.L.2
  • 331
    • 0026573574 scopus 로고
    • Metabolism of glyceryl trinitrate to nitric oxide by endothelial cells and smooth muscle cells and its induction by E. coli lipopolysaccharide
    • Salvemini D, Mollace V, Pistelli A, Angard E, and Vane J (1992a) Metabolism of glyceryl trinitrate to nitric oxide by endothelial cells and smooth muscle cells and its induction by E. coli lipopolysaccharide. Proc Natl Acad Sci USA 89:982-986.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 982-986
    • Salvemini, D.1    Mollace, V.2    Pistelli, A.3    Angard, E.4    Vane, J.5
  • 332
    • 0027131834 scopus 로고
    • Vascular anti-platelet action of 1,2- and 1,3-glyceryl dinitrate
    • Salvemini D, Pistelli A, and Anggard E (1993b) Vascular anti-platelet action of 1,2-and 1,3-glyceryl dinitrate. Br J Pharmacol 110:937-942.
    • (1993) Br J Pharmacol , vol.110 , pp. 937-942
    • Salvemini, D.1    Pistelli, A.2    Anggard, E.3
  • 333
    • 0026752673 scopus 로고
    • The metabolism of glyceryl trinitrate to nitric oxide in the macrophage
    • Salvemini D, Pistelli A, Mollace V, Angard E, and Vane J (1992b) The metabolism of glyceryl trinitrate to nitric oxide in the macrophage cell line J774 and its induction by E. coli lipopolysaccharide. Biochem Pharmacol 44:17-24.
    • (1992) Biochem Pharmacol , vol.44 , pp. 17-24
    • Salvemini, D.1    Pistelli, A.2    Mollace, V.3    Angard, E.4    Vane, J.5
  • 334
    • 0027455003 scopus 로고
    • Conversion of glyceryl trinitrate to nitric oxide in tolerant smooth muscle cells and endothelial cells
    • Salvemini D, Pistelli A, and Vane J (1993c) Conversion of glyceryl trinitrate to nitric oxide in tolerant smooth muscle cells and endothelial cells. Br J Pharmacol 108:162-169.
    • (1993) Br J Pharmacol , vol.108 , pp. 162-169
    • Salvemini, D.1    Pistelli, A.2    Vane, J.3
  • 335
    • 0025202072 scopus 로고
    • The use of oxyhaemoglobin to explore the events underlying inhibition of platelet aggregation induced by NO or NO-donors
    • Salvemini D, Radziszewski W, Korbut R, and Vane J (1990b) The use of oxyhaemoglobin to explore the events underlying inhibition of platelet aggregation induced by NO or NO-donors. Br J Pharmacol 101:991-995.
    • (1990) Br J Pharmacol , vol.101 , pp. 991-995
    • Salvemini, D.1    Radziszewski, W.2    Korbut, R.3    Vane, J.4
  • 341
    • 0026531534 scopus 로고
    • In vivo COX expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis
    • Sano H, Hla T, Maier JA, Crofford LJ, Case JP, Maciag T, and Wilder RL (1992) In vivo COX expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis. J Clin Investig 89:97-108.
    • (1992) J Clin Investig , vol.89 , pp. 97-108
    • Sano, H.1    Hla, T.2    Maier, J.A.3    Crofford, L.J.4    Case, J.P.5    Maciag, T.6    Wilder, R.L.7
  • 344
    • 0018874138 scopus 로고
    • Inhibition of platelet function by organic nitrate vasodilators
    • Schafer AI, Alexander RW, and Handin RI (1980) Inhibition of platelet function by organic nitrate vasodilators. Blood 55:649-654.
    • (1980) Blood , vol.55 , pp. 649-654
    • Schafer, A.I.1    Alexander, R.W.2    Handin, R.I.3
  • 346
    • 0005856976 scopus 로고
    • Cytochrome P450 mediates bioactivation of glyceryl trinitrate in cultured cells
    • Portland Press, London
    • Schroder H and Schror K (1992) Cytochrome P450 mediates bioactivation of glyceryl trinitrate in cultured cells, in Biology of Nitric Oxide, pp 65-73, vol 7, Portland Press, London.
    • (1992) Biology of Nitric Oxide , vol.7 , pp. 65-73
    • Schroder, H.1    Schror, K.2
  • 349
    • 0034332975 scopus 로고    scopus 로고
    • Persistent accumulation of cyclooxygenase-1 (COX-1)-expressing microglia/macrophages and upregulation by endothelium following spinal cord injury
    • Schwab JM, Brechtel K, Nguyen TD, and Schluesener HJ (2000a) Persistent accumulation of cyclooxygenase-1 (COX-1)-expressing microglia/macrophages and upregulation by endothelium following spinal cord injury. J Neuroimmunol 111:122-130.
    • (2000) J Neuroimmunol , vol.111 , pp. 122-130
    • Schwab, J.M.1    Brechtel, K.2    Nguyen, T.D.3    Schluesener, H.J.4
  • 350
    • 0034107377 scopus 로고    scopus 로고
    • Selective accumulation of cyclooxygenase-1-expressing microglial cells/macrophages in lesions of human focal cerebral ischemia
    • Schwab JM, Nguyen TD, Postler E, Meyermann R, and Schluesener HJ (2000b) Selective accumulation of cyclooxygenase-1-expressing microglial cells/macrophages in lesions of human focal cerebral ischemia. Acta Neuropathol 99: 609-614.
    • (2000) Acta Neuropathol , vol.99 , pp. 609-614
    • Schwab, J.M.1    Nguyen, T.D.2    Postler, E.3    Meyermann, R.4    Schluesener, H.J.5
  • 353
    • 0024407598 scopus 로고
    • Nitric oxide formation during microsomal hepatic denitration of glyceryl trinitrate: Involvement of cytochrome P450
    • Servent D, Delaforge M, Ducrocq C, Mansuy D, and Lenfant M (1989) Nitric oxide formation during microsomal hepatic denitration of glyceryl trinitrate: involvement of cytochrome P450. Biochem Biophys Res Commun 163:1210-1216.
    • (1989) Biochem Biophys Res Commun , vol.163 , pp. 1210-1216
    • Servent, D.1    Delaforge, M.2    Ducrocq, C.3    Mansuy, D.4    Lenfant, M.5
  • 355
    • 0030979486 scopus 로고    scopus 로고
    • Substituted N-phenylisothioureas: Potent inhibitors of human nitric oxide synthase with neuronal isoform selectivity
    • Shearer BG, Lee S, Oplinger JA, Frick LW, Garvey EP, and Furfine ES (1997) Substituted N-phenylisothioureas: potent inhibitors of human nitric oxide synthase with neuronal isoform selectivity. J Med Chem 40:1901-1905.
    • (1997) J Med Chem , vol.40 , pp. 1901-1905
    • Shearer, B.G.1    Lee, S.2    Oplinger, J.A.3    Frick, L.W.4    Garvey, E.P.5    Furfine, E.S.6
  • 356
    • 0029050903 scopus 로고
    • Nitric oxide production and NO synthase gene expression contribute to vascular regulation during exercise
    • Shen W, Zhang X, Zhao G, Wolin MS, Sessa W, and Hintze TH (1995) Nitric oxide production and NO synthase gene expression contribute to vascular regulation during exercise. Med Sci Sports Exerc 27:1125-1134.
    • (1995) Med Sci Sports Exerc , vol.27 , pp. 1125-1134
    • Shen, W.1    Zhang, X.2    Zhao, G.3    Wolin, M.S.4    Sessa, W.5    Hintze, T.H.6
  • 357
    • 0031984810 scopus 로고    scopus 로고
    • Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells
    • Sheng H, Shao J, Morrow JD, Beauchamp RD, and Dubois RN (1998) Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res 58:362-366.
    • (1998) Cancer Res , vol.58 , pp. 362-366
    • Sheng, H.1    Shao, J.2    Morrow, J.D.3    Beauchamp, R.D.4    Dubois, R.N.5
  • 358
    • 0027372580 scopus 로고
    • Purification and cDNA sequence of an inducible NO synthase from a human tumor cell line
    • Sherman PA, Laubach VE, Reep BR, and Wood ER (1993) Purification and cDNA sequence of an inducible NO synthase from a human tumor cell line. Biochemistry 32:11600-11605.
    • (1993) Biochemistry , vol.32 , pp. 11600-11605
    • Sherman, P.A.1    Laubach, V.E.2    Reep, B.R.3    Wood, E.R.4
  • 359
    • 0026078822 scopus 로고
    • Endogenous NO release required for long-term synaptic depression in the cerebellum
    • Shibuki K and Okada D (1991) Endogenous NO release required for long-term synaptic depression in the cerebellum. Nature (Lond) 349:326-328.
    • (1991) Nature (Lond) , vol.349 , pp. 326-328
    • Shibuki, K.1    Okada, D.2
  • 360
    • 0037155779 scopus 로고    scopus 로고
    • Inducible NO synthase modulates COX-2 activity in the heart of conscious rabbits during the late phase of ischemic preconditioning
    • Shinmura K, Xuan YT, Tang XL, Kodani E, Han H, Zhu Y, and Bolli R (2002) Inducible NO synthase modulates COX-2 activity in the heart of conscious rabbits during the late phase of ischemic preconditioning. Circ Res 90:602-608.
    • (2002) Circ Res , vol.90 , pp. 602-608
    • Shinmura, K.1    Xuan, Y.T.2    Tang, X.L.3    Kodani, E.4    Han, H.5    Zhu, Y.6    Bolli, R.7
  • 361
    • 0029933799 scopus 로고    scopus 로고
    • Neuronal NO synthase-mu, an alternatively spliced isoform expressed in differentiated skeletal muscle
    • Silvagno F, Xia H, and Bredt DS (1996) Neuronal NO synthase-mu, an alternatively spliced isoform expressed in differentiated skeletal muscle. J Biol Chem 19:11204-11208.
    • (1996) J Biol Chem , vol.19 , pp. 11204-11208
    • Silvagno, F.1    Xia, H.2    Bredt, D.S.3
  • 363
    • 0026744831 scopus 로고
    • Purification and characterization of a novel, distinct isoform of prostaglandin endoperoxide synthase induced by human chorionic gonadotropin in granulosa cells of rat preovulatory follicles
    • Sirois J and Richards JS (1992) Purification and characterization of a novel, distinct isoform of prostaglandin endoperoxide synthase induced by human chorionic gonadotropin in granulosa cells of rat preovulatory follicles. J Biol Chem 267:6382-6388.
    • (1992) J Biol Chem , vol.267 , pp. 6382-6388
    • Sirois, J.1    Richards, J.S.2
  • 364
    • 0030106245 scopus 로고    scopus 로고
    • Progressive activation of adult microglial cells in vitro
    • Slepko N and Levi G (1996) Progressive activation of adult microglial cells in vitro. Glia 16:241-246.
    • (1996) Glia , vol.16 , pp. 241-246
    • Slepko, N.1    Levi, G.2
  • 365
    • 0038730715 scopus 로고    scopus 로고
    • Platelet-activating factor modulates gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide
    • Slomiany BL and Slomiany A (2003) Platelet-activating factor modulates gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide. Biochem Biophys Res Commun 306:261-266.
    • (2003) Biochem Biophys Res Commun , vol.306 , pp. 261-266
    • Slomiany, B.L.1    Slomiany, A.2
  • 366
    • 0030628655 scopus 로고    scopus 로고
    • Colorectal cancer and nonsteroidal antiinflammatory drugs
    • Smalley WE and Dubois RN (1997) Colorectal cancer and nonsteroidal antiinflammatory drugs. Adv Pharmacol 39:1-20.
    • (1997) Adv Pharmacol , vol.39 , pp. 1-20
    • Smalley, W.E.1    Dubois, R.N.2
  • 367
    • 0015510101 scopus 로고
    • Oxygenation of polyunsaturated fatty acids during prostaglandin biosynthesis by sheep vesicular gland
    • Smith WL and Lands WE (1972) Oxygenation of polyunsaturated fatty acids during prostaglandin biosynthesis by sheep vesicular gland. Biochemistry 11:3276-3285.
    • (1972) Biochemistry , vol.11 , pp. 3276-3285
    • Smith, W.L.1    Lands, W.E.2
  • 368
  • 369
    • 0031420473 scopus 로고    scopus 로고
    • Interaction of PGH synthase isozymes-1 and -2 with nonsteroidal anti-inflammatory drugs
    • Smith WL, Meade EA, and Dewitt DL (1997) Interaction of PGH synthase isozymes-1 and -2 with nonsteroidal anti-inflammatory drugs. Adv Exp Med Biol 400A:189-196.
    • (1997) Adv Exp Med Biol , vol.400 A , pp. 189-196
    • Smith, W.L.1    Meade, E.A.2    Dewitt, D.L.3
  • 370
    • 0004916124 scopus 로고
    • Endothelium-derived relaxing factor reduces platelet adhesion to bovine endothelial cells
    • Sneddon JM and Vane JR (1988) Endothelium-derived relaxing factor reduces platelet adhesion to bovine endothelial cells. Proc Natl Acad Sci USA 85:2800-2804.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 2800-2804
    • Sneddon, J.M.1    Vane, J.R.2
  • 371
    • 0026531834 scopus 로고
    • Biological roles of NO
    • Snyder SH and Bredt DS (1992) Biological roles of NO. Sci Am 266:68-71.
    • (1992) Sci Am , vol.266 , pp. 68-71
    • Snyder, S.H.1    Bredt, D.S.2
  • 372
    • 0028847367 scopus 로고
    • Amidines are potent inhibitors of nitric oxide synthases: Preferential inhibition of the inducible isoform
    • Southan GJ, Szabo C, Connor MP, Salzman AL, and Thiemermann C (1995) Amidines are potent inhibitors of nitric oxide synthases: preferential inhibition of the inducible isoform. Eur J Pharmacol 291:311-318.
    • (1995) Eur J Pharmacol , vol.291 , pp. 311-318
    • Southan, G.J.1    Szabo, C.2    Connor, M.P.3    Salzman, A.L.4    Thiemermann, C.5
  • 373
    • 33444461442 scopus 로고
    • Biotransformation of organic nitrates to NO by cytosolic and microsomal glutathione-S-transferase
    • Portland Press, London
    • Spahr R, Knuttel A, Tholen A, and Feelisch M (1994) Biotransformation of organic nitrates to NO by cytosolic and microsomal glutathione-S-transferase, in Biology of Nitric Oxide, pp 15-24, Portland Press, London.
    • (1994) Biology of Nitric Oxide , pp. 15-24
    • Spahr, R.1    Knuttel, A.2    Tholen, A.3    Feelisch, M.4
  • 374
    • 0036943957 scopus 로고    scopus 로고
    • Induction of the complement component C1qB in brain of transgenic mice with neuronal overexpression of human cyclooxygenase-2
    • Spielman L, Winger D, Ho L, Aisen PS, Shohami E, and Pasinetti GM (2002) Induction of the complement component C1qB in brain of transgenic mice with neuronal overexpression of human cyclooxygenase-2. Acta Neuropathol (Berl) 103:157-162.
    • (2002) Acta Neuropathol (Berl) , vol.103 , pp. 157-162
    • Spielman, L.1    Winger, D.2    Ho, L.3    Aisen, P.S.4    Shohami, E.5    Pasinetti, G.M.6
  • 376
    • 0025907694 scopus 로고
    • Diclofenac delays healing of gastroduodenal mucosal lesions. Double-blind, placebo-controlled endoscopic study in healthy volunteers
    • Stadler P, Armstrong D, Margalith D, Saraga E, Stolte M, Lualdi P, Mautone G, and Blum AL (1991) Diclofenac delays healing of gastroduodenal mucosal lesions. Double-blind, placebo-controlled endoscopic study in healthy volunteers. Dig Dis Sci 36:594-600.
    • (1991) Dig Dis Sci , vol.36 , pp. 594-600
    • Stadler, P.1    Armstrong, D.2    Margalith, D.3    Saraga, E.4    Stolte, M.5    Lualdi, P.6    Mautone, G.7    Blum, A.L.8
  • 378
    • 0025993387 scopus 로고
    • The antiplatelet effects of organic nitrates and related nitroso compounds in vitro and in vivo and their relevance to cardiovascular disorders
    • Stamler JS and Loscalzo J (1991) The antiplatelet effects of organic nitrates and related nitroso compounds in vitro and in vivo and their relevance to cardiovascular disorders. J Am Coll Cardiol 18:1529-1536.
    • (1991) J Am Coll Cardiol , vol.18 , pp. 1529-1536
    • Stamler, J.S.1    Loscalzo, J.2
  • 379
    • 0035139227 scopus 로고    scopus 로고
    • Physiology of nitric oxide in skeletal muscle
    • Stamler JS and Meissner G (2001) Physiology of nitric oxide in skeletal muscle. Physiol Rev 81:209-237.
    • (2001) Physiol Rev , vol.81 , pp. 209-237
    • Stamler, J.S.1    Meissner, G.2
  • 380
    • 0026660191 scopus 로고
    • Spectral characterization of brain and macrophage NO synthases. Cytochrome P-450-like hemeproteins that contain a flavin semiquinone radical
    • Stuehr DJ and Ikeda-Saito M (1992) Spectral characterization of brain and macrophage NO synthases. Cytochrome P-450-like hemeproteins that contain a flavin semiquinone radical. J Biol Chem 267:20547-20550.
    • (1992) J Biol Chem , vol.267 , pp. 20547-20550
    • Stuehr, D.J.1    Ikeda-Saito, M.2
  • 381
    • 0028942559 scopus 로고
    • Coinduction of nitric oxide synthase and cyclo-oxygenase: Interactions between nitric oxide and prostanoids
    • Swierkosz TA, Mitchell JA, Warner TD, Botting RM, and Vane JR (1995) Coinduction of nitric oxide synthase and cyclo-oxygenase: interactions between nitric oxide and prostanoids. Br J Pharmacol 114:1335-1342.
    • (1995) Br J Pharmacol , vol.114 , pp. 1335-1342
    • Swierkosz, T.A.1    Mitchell, J.A.2    Warner, T.D.3    Botting, R.M.4    Vane, J.R.5
  • 382
    • 0029790939 scopus 로고    scopus 로고
    • Physiological and pathophysiological roles of NO in the central nervous system
    • Szabo C (1996) Physiological and pathophysiological roles of NO in the central nervous system. Brain Res Bull 41:131-141.
    • (1996) Brain Res Bull , vol.41 , pp. 131-141
    • Szabo, C.1
  • 383
    • 0037432615 scopus 로고    scopus 로고
    • Multiple pathways of peroxynitrite cytotoxicity
    • Szabo C (2003) Multiple pathways of peroxynitrite cytotoxicity. Toxicol Lett 140-141:105-112.
    • (2003) Toxicol Lett , vol.140-141 , pp. 105-112
    • Szabo, C.1
  • 384
    • 0029444877 scopus 로고
    • Regulation of the expression of the inducible isoform of nitric oxide synthase
    • Szabò C and Thiemermann C (1995) Regulation of the expression of the inducible isoform of nitric oxide synthase. Adv Pharmacol 34:113-153.
    • (1995) Adv Pharmacol , vol.34 , pp. 113-153
    • Szabò, C.1    Thiemermann, C.2
  • 386
    • 0037059399 scopus 로고    scopus 로고
    • Prostaglandin E(2) induces caspase-dependent apoptosis in rat cortical cells
    • Takadera T, Yumoto H, Tozuka Y, and Ohyashiki T (2002) Prostaglandin E(2) induces caspase-dependent apoptosis in rat cortical cells. Neurosci Lett 317:61-64.
    • (2002) Neurosci Lett , vol.317 , pp. 61-64
    • Takadera, T.1    Yumoto, H.2    Tozuka, Y.3    Ohyashiki, T.4
  • 387
    • 0036714284 scopus 로고    scopus 로고
    • COX and NOS isoforms involved in acid-induced duodenal bicarbonate secretion in rats
    • Takeuchi K, Kagawa S, Mimaki H, Aoi M, and Kawauchi S (2002) COX and NOS isoforms involved in acid-induced duodenal bicarbonate secretion in rats. Dig Dis Sci 47:2116-2124.
    • (2002) Dig Dis Sci , vol.47 , pp. 2116-2124
    • Takeuchi, K.1    Kagawa, S.2    Mimaki, H.3    Aoi, M.4    Kawauchi, S.5
  • 388
    • 0024388901 scopus 로고
    • Macrophage oxidation of L-arginine to NO, nitrite and nitrate. Tetrahydrobiopterin is required as a cofactor
    • Tayeh MA and Marletta MA (1989) Macrophage oxidation of L-arginine to NO, nitrite and nitrate. Tetrahydrobiopterin is required as a cofactor. J Biol Chem 264:19654-19658.
    • (1989) J Biol Chem , vol.264 , pp. 19654-19658
    • Tayeh, M.A.1    Marletta, M.A.2
  • 389
    • 0035177677 scopus 로고    scopus 로고
    • Effects of selective COX-1 and -2 inhibition on formalin-evoked nociceptive behaviour and prostaglandin E(2) release in the spinal cord
    • Tegeder I, Niederberger E, Vetter G, Brautigam L, and Geisslinger G (2001) Effects of selective COX-1 and -2 inhibition on formalin-evoked nociceptive behaviour and prostaglandin E(2) release in the spinal cord. J Neurochem 79:777-786.
    • (2001) J Neurochem , vol.79 , pp. 777-786
    • Tegeder, I.1    Niederberger, E.2    Vetter, G.3    Brautigam, L.4    Geisslinger, G.5
  • 391
    • 0035968743 scopus 로고    scopus 로고
    • Aspirin and non-steroidal antiinflammatory drugs inhibit amyloid-beta aggregation
    • Thomas T, Nadackal TG, and Thomas K (2001) Aspirin and non-steroidal antiinflammatory drugs inhibit amyloid-beta aggregation. Neuroreport 12:3263-3267.
    • (2001) Neuroreport , vol.12 , pp. 3263-3267
    • Thomas, T.1    Nadackal, T.G.2    Thomas, K.3
  • 392
    • 0031740961 scopus 로고    scopus 로고
    • NO synthase activity in fresh cells from ovarian tumour tissue: Relationship of enzyme activity with clinical parameters of patients with ovarian cancer
    • Thomsen LL, Sargent JM, Williamson CJ, and Elgie AW (1998) NO synthase activity in fresh cells from ovarian tumour tissue: relationship of enzyme activity with clinical parameters of patients with ovarian cancer. Biochem Pharmacol 56:1365-1370.
    • (1998) Biochem Pharmacol , vol.56 , pp. 1365-1370
    • Thomsen, L.L.1    Sargent, J.M.2    Williamson, C.J.3    Elgie, A.W.4
  • 393
    • 0030877443 scopus 로고    scopus 로고
    • Selective inhibition of inducible NO synthase inhibits tumor growth in vivo: Studies with 1400W, a novel inhibitor
    • Thomsen LL, Scott JM, Topley P, Knowles RG, Keerie AJ, and Frend AJ (1997) Selective inhibition of inducible NO synthase inhibits tumor growth in vivo: studies with 1400W, a novel inhibitor. Cancer Res 57:3300-3304.
    • (1997) Cancer Res , vol.57 , pp. 3300-3304
    • Thomsen, L.L.1    Scott, J.M.2    Topley, P.3    Knowles, R.G.4    Keerie, A.J.5    Frend, A.J.6
  • 394
    • 0025998557 scopus 로고
    • Aspirin use and reduced risk of fatal colon cancer
    • Thun MJ, Namboodiri MM, and Heath CW Jr (1991) Aspirin use and reduced risk of fatal colon cancer. N Engl J Med 325:1593-1596.
    • (1991) N Engl J Med , vol.325 , pp. 1593-1596
    • Thun, M.J.1    Namboodiri, M.M.2    Heath Jr., C.W.3
  • 395
    • 0030938587 scopus 로고    scopus 로고
    • Neuronal (type I) nitric oxide synthase regulates nuclear factor kappaB activity and immunologic (type II) nitric oxide synthase expression
    • Togashi H, Sasaki M, Frohman E, Taira E, Ratan RR, Dawson TM, and Dawson VL (1997) Neuronal (type I) nitric oxide synthase regulates nuclear factor kappaB activity and immunologic (type II) nitric oxide synthase expression. Proc Natl Acad Sci USA 94:2676-2680.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2676-2680
    • Togashi, H.1    Sasaki, M.2    Frohman, E.3    Taira, E.4    Ratan, R.R.5    Dawson, T.M.6    Dawson, V.L.7
  • 396
    • 0036938594 scopus 로고    scopus 로고
    • A comparative study on the expression of cyclooxygenase and 5-lipoxygenase during cerebral ischemia in humans
    • Tomimoto H, Shibata M, Ihara M, Akiguchi I, Ohtani R, and Budka H (2002) A comparative study on the expression of cyclooxygenase and 5-lipoxygenase during cerebral ischemia in humans. Acta Neuropathol (Berl) 104:601-607.
    • (2002) Acta Neuropathol (Berl) , vol.104 , pp. 601-607
    • Tomimoto, H.1    Shibata, M.2    Ihara, M.3    Akiguchi, I.4    Ohtani, R.5    Budka, H.6
  • 398
    • 0028048310 scopus 로고
    • Interaction between nitric oxide and prostaglandin H synthase
    • Tsai AL, Wei C, and Kulmacz RJ (1994) Interaction between nitric oxide and prostaglandin H synthase. Arch Biochem Biophys 313:367-372.
    • (1994) Arch Biochem Biophys , vol.313 , pp. 367-372
    • Tsai, A.L.1    Wei, C.2    Kulmacz, R.J.3
  • 399
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii M and Dubois RN (1995) Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 83:493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    Dubois, R.N.2
  • 402
    • 0033592251 scopus 로고    scopus 로고
    • Regulation of PGH2 synthase activity by nitrogen oxides
    • Upmacis RK, Deeb RS, and Hajjar DP (1999) Regulation of PGH2 synthase activity by nitrogen oxides. Biochemistry 38:12505-12513.
    • (1999) Biochemistry , vol.38 , pp. 12505-12513
    • Upmacis, R.K.1    Deeb, R.S.2    Hajjar, D.P.3
  • 403
    • 85047678425 scopus 로고
    • NO synthesised from L-arginine mediates endothelium dependent dilatation in human veins in vivo
    • Vallance P, Collier J, and Moncada S (1989) NO synthesised from L-arginine mediates endothelium dependent dilatation in human veins in vivo. Cardiovasc Res 23:1053-1057.
    • (1989) Cardiovasc Res , vol.23 , pp. 1053-1057
    • Vallance, P.1    Collier, J.2    Moncada, S.3
  • 404
    • 0026548912 scopus 로고
    • Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
    • Vallance P, Leone A, Calver A, Collier J, and Moncada S (1992) Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 339:572-575.
    • (1992) Lancet , vol.339 , pp. 572-575
    • Vallance, P.1    Leone, A.2    Calver, A.3    Collier, J.4    Moncada, S.5
  • 405
    • 0017335606 scopus 로고
    • Purification and characterisation of PG endoperoxide synthetase from sheep vesicular glands
    • Van der Ouderaa FJ, Buytenhek M, Nugteren DH, and Van Dorp DA (1977) Purification and characterisation of PG endoperoxide synthetase from sheep vesicular glands. Biochim Biophys Acta 487:315-331.
    • (1977) Biochim Biophys Acta , vol.487 , pp. 315-331
    • Van Der Ouderaa, F.J.1    Buytenhek, M.2    Nugteren, D.H.3    Van Dorp, D.A.4
  • 406
    • 0015237292 scopus 로고
    • Inhibition of PG synthesis as a mechanism of action for aspirin-like drugs
    • Vane JR (1971) Inhibition of PG synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol 231:232-235.
    • (1971) Nat New Biol , vol.231 , pp. 232-235
    • Vane, J.R.1
  • 407
    • 0025334367 scopus 로고
    • Regulatory functions of the vascular endothelium
    • Vane JR, Anggard EE, and Botting RM (1990) Regulatory functions of the vascular endothelium. N Engl J Med 323:27-36.
    • (1990) N Engl J Med , vol.323 , pp. 27-36
    • Vane, J.R.1    Anggard, E.E.2    Botting, R.M.3
  • 408
    • 0029928405 scopus 로고    scopus 로고
    • Mechanism of action of anti-inflammatory drugs
    • Vane JR and Botting RM (1996) Mechanism of action of anti-inflammatory drugs. Scand J Rheumatol Suppl 102:9-21.
    • (1996) Scand J Rheumatol Suppl , vol.102 , pp. 9-21
    • Vane, J.R.1    Botting, R.M.2
  • 410
    • 0035081365 scopus 로고    scopus 로고
    • Prostaglandins and cyclooxygenases [correction of cycloxygenases] in the spinal cord
    • Vanegas H and Schaible HG (2001) Prostaglandins and cyclooxygenases [correction of cycloxygenases] in the spinal cord. Prog Neurobiol 64:327-363.
    • (2001) Prog Neurobiol , vol.64 , pp. 327-363
    • Vanegas, H.1    Schaible, H.G.2
  • 411
    • 0036069555 scopus 로고    scopus 로고
    • Aspirin provides cyclin-dependent kinase 5-dependent protection against subsequent hypoxia/reoxygenation damage in culture
    • Vartiainen N, Keksa-Goldsteine V, Goldsteins G, and Koistinaho J (2002) Aspirin provides cyclin-dependent kinase 5-dependent protection against subsequent hypoxia/reoxygenation damage in culture. J Neurochem 82:329-335.
    • (2002) J Neurochem , vol.82 , pp. 329-335
    • Vartiainen, N.1    Keksa-Goldsteine, V.2    Goldsteins, G.3    Koistinaho, J.4
  • 412
    • 0037189121 scopus 로고    scopus 로고
    • Involvement of COX and NOS induction in the sympatho-activation during sepsis
    • Vayssettes-Courchay C, Bouysset F, and Verbeuren TJ (2002) Involvement of COX and NOS induction in the sympatho-activation during sepsis. Auton Neurosci 98:33-36.
    • (2002) Auton Neurosci , vol.98 , pp. 33-36
    • Vayssettes-Courchay, C.1    Bouysset, F.2    Verbeuren, T.J.3
  • 414
    • 0026650126 scopus 로고
    • A role for the arachidonic acid cascade in fast synaptic modulation: Ion channels and transmitter uptake systems as target proteins
    • Volterra A, Trotti D, Cassutti P, Tromba C, Galimberti R, Lecchi P, and Racagni G (1992) A role for the arachidonic acid cascade in fast synaptic modulation: ion channels and transmitter uptake systems as target proteins. Adv Exp Med Biol 318:147-158.
    • (1992) Adv Exp Med Biol , vol.318 , pp. 147-158
    • Volterra, A.1    Trotti, D.2    Cassutti, P.3    Tromba, C.4    Galimberti, R.5    Lecchi, P.6    Racagni, G.7
  • 415
    • 0027944554 scopus 로고
    • Glutamate uptake is inhibited by arachidonic acid and oxygen radicals via two distinct and additive mechanisms
    • Volterra A, Trotti D, and Racagni G (1994) Glutamate uptake is inhibited by arachidonic acid and oxygen radicals via two distinct and additive mechanisms. Mol Pharmacol 46:986-992.
    • (1994) Mol Pharmacol , vol.46 , pp. 986-992
    • Volterra, A.1    Trotti, D.2    Racagni, G.3
  • 416
    • 1842332149 scopus 로고    scopus 로고
    • COX-2: An essential regulator of NO-mediated apoptosis
    • Von Knethen A and Brune B (1997) COX-2: an essential regulator of NO-mediated apoptosis. FASEB J 11:887-895.
    • (1997) FASEB J , vol.11 , pp. 887-895
    • Von Knethen, A.1    Brune, B.2
  • 417
    • 0020957238 scopus 로고
    • Mammalian nitrate biosynthesis: Incorporation of 15NH3 into nitrate is enhanced by endotoxin treatment
    • Wagner DA, Young VR, and Tannenbaum SR (1983) Mammalian nitrate biosynthesis: incorporation of 15NH3 into nitrate is enhanced by endotoxin treatment. Proc Natl Acad Sci USA 80:4518-4521.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 4518-4521
    • Wagner, D.A.1    Young, V.R.2    Tannenbaum, S.R.3
  • 419
    • 0025803673 scopus 로고
    • The involvement of endothelium-derived relaxing factor in the regulation of renal cortical blood flow in the rat
    • Walder CE, Thiemermann C, and Vane JR (1991) The involvement of endothelium-derived relaxing factor in the regulation of renal cortical blood flow in the rat. Br J Pharmacol 102:967-973.
    • (1991) Br J Pharmacol , vol.102 , pp. 967-973
    • Walder, C.E.1    Thiemermann, C.2    Vane, J.R.3
  • 420
    • 0242586340 scopus 로고    scopus 로고
    • Effects of free radicals on coronary artery
    • Walia M, Kwan CY, and Grover AK (2003) Effects of free radicals on coronary artery. Med Princ Pract 12:1-9.
    • (2003) Med Princ Pract , vol.12 , pp. 1-9
    • Walia, M.1    Kwan, C.Y.2    Grover, A.K.3
  • 421
    • 0032973694 scopus 로고    scopus 로고
    • Selective COX-2 inhibitors: Is the water becoming muddy?
    • Wallace JL (1999) Selective COX-2 inhibitors: is the water becoming muddy? Trends Pharmacol Sci 20:4-6.
    • (1999) Trends Pharmacol Sci , vol.20 , pp. 4-6
    • Wallace, J.L.1
  • 422
    • 0031749806 scopus 로고    scopus 로고
    • COX 1 contributes to inflammatory responses in rats and mice: Implications for gastrointestinal toxicity
    • Wallace JL, Bak A, McKnight W, Asfaha S, Sharkey KA, and MacNaughton WK (1998) COX 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity. Gastroenterology 115:101-109.
    • (1998) Gastroenterology , vol.115 , pp. 101-109
    • Wallace, J.L.1    Bak, A.2    McKnight, W.3    Asfaha, S.4    Sharkey, K.A.5    MacNaughton, W.K.6
  • 423
    • 0028035254 scopus 로고
    • The development of gastrointestinal-sparing nonsteroidal anti-inflammatory drugs
    • Wallace JL and Cirino G (1994) The development of gastrointestinal- sparing nonsteroidal anti-inflammatory drugs. Trends Pharmacol Sci 15:405-406.
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 405-406
    • Wallace, J.L.1    Cirino, G.2
  • 425
    • 0031408178 scopus 로고    scopus 로고
    • Reduction of shock-induced gastric damage by a nitric oxide-releasing aspirin derivative: Role of neutrophils
    • Wallace JL, McKnight W, Wilson TL, Del Soldato P, and Cirino G (1997) Reduction of shock-induced gastric damage by a nitric oxide-releasing aspirin derivative: role of neutrophils. Am J Physiol 273:G1246-G1251.
    • (1997) Am J Physiol , vol.273
    • Wallace, J.L.1    McKnight, W.2    Wilson, T.L.3    Del Soldato, P.4    Cirino, G.5
  • 426
  • 427
    • 0033594911 scopus 로고    scopus 로고
    • Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis
    • Warner TD, Giuliano F, Vojnovic I, Bukasa A, Mitchell JA, and Vane JR (1999) Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci USA 96:7563-7568.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7563-7568
    • Warner, T.D.1    Giuliano, F.2    Vojnovic, I.3    Bukasa, A.4    Mitchell, J.A.5    Vane, J.R.6
  • 428
    • 0037108781 scopus 로고    scopus 로고
    • Cyclooxygenase-3 (COX-3): Filling in the gaps toward a COX continuum?
    • Warner TD and Mitchell JA (2002) Cyclooxygenase-3 (COX-3): filling in the gaps toward a COX continuum? Proc Natl Acad Sci USA 99:13371-13373.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13371-13373
    • Warner, T.D.1    Mitchell, J.A.2
  • 429
    • 0030751783 scopus 로고    scopus 로고
    • Regulation of the inducible cyclo-oxygenase pathway in human cultured airway epithelial (A549) cells by NO
    • Watkins DN, Garlepp MJ, and Thompson PJ (1997) Regulation of the inducible cyclo-oxygenase pathway in human cultured airway epithelial (A549) cells by NO. Br J Pharmacol 121:1482-1488.
    • (1997) Br J Pharmacol , vol.121 , pp. 1482-1488
    • Watkins, D.N.1    Garlepp, M.J.2    Thompson, P.J.3
  • 431
    • 0029133539 scopus 로고
    • Human mononuclear phagocyte inducible NO synthase (iNOS): Analysis of iNOS mRNA, iNOS protein, biopterin and NO production by blood monocyte and peritoneal macrophages
    • Weinberg JB, Misukonis MA, Shami PJ, Mason SN, Sauls DL, Dittman WA, Wood ER, Smith GK, McDonald B, and Bachus KE (1995) Human mononuclear phagocyte inducible NO synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin and NO production by blood monocyte and peritoneal macrophages. Blood 86:1184-1195.
    • (1995) Blood , vol.86 , pp. 1184-1195
    • Weinberg, J.B.1    Misukonis, M.A.2    Shami, P.J.3    Mason, S.N.4    Sauls, D.L.5    Dittman, W.A.6    Wood, E.R.7    Smith, G.K.8    McDonald, B.9    Bachus, K.E.10
  • 432
    • 0035811229 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibition and renal function
    • Whelton A (2001) Cyclooxygenase-2 inhibition and renal function. Ann Intern Med 134:1077-1078.
    • (2001) Ann Intern Med , vol.134 , pp. 1077-1078
    • Whelton, A.1
  • 433
    • 0035286901 scopus 로고    scopus 로고
    • COX-2-specific inhibitors and cardiorenal function: A randomized, controlled trial of celecoxib and rofecoxib in older hypertensive osteoarthritis patients
    • Whelton A, Fort JG, Puma JA, Normandin D, Bello AE, and Verburg KM (2001) COX-2-specific inhibitors and cardiorenal function: a randomized, controlled trial of celecoxib and rofecoxib in older hypertensive osteoarthritis patients. Am J Ther 8:85-95.
    • (2001) Am J Ther , vol.8 , pp. 85-95
    • Whelton, A.1    Fort, J.G.2    Puma, J.A.3    Normandin, D.4    Bello, A.E.5    Verburg, K.M.6
  • 434
    • 0026735580 scopus 로고
    • NO synthase is a cytochrome P-450 type hemoprotein
    • White KA and Marletta MA (1992) NO synthase is a cytochrome P-450 type hemoprotein. Biochemistry 31:6627-6631.
    • (1992) Biochemistry , vol.31 , pp. 6627-6631
    • White, K.A.1    Marletta, M.A.2
  • 435
    • 0024428650 scopus 로고
    • Modulation of the vasodepressor actions of acetylcholine, bradykinin, substance P and endothelin in the rat by a specific inhibitor of NO formation
    • Whittle BJ, Lopez-Belmonte J, and Rees DD (1989) Modulation of the vasodepressor actions of acetylcholine, bradykinin, substance P and endothelin in the rat by a specific inhibitor of NO formation. Br J Pharmacol 98:646-652.
    • (1989) Br J Pharmacol , vol.98 , pp. 646-652
    • Whittle, B.J.1    Lopez-Belmonte, J.2    Rees, D.D.3
  • 436
    • 0018197723 scopus 로고
    • Some actions of prostacyclin (PGI2) on the cardiovascular system and the gastric microcirculation
    • Whittle BJ, Moncada S, and Vane JR (1978) Some actions of prostacyclin (PGI2) on the cardiovascular system and the gastric microcirculation. Acta Biol Med Ger 37:725-728.
    • (1978) Acta Biol Med Ger , vol.37 , pp. 725-728
    • Whittle, B.J.1    Moncada, S.2    Vane, J.R.3
  • 437
    • 0030770386 scopus 로고    scopus 로고
    • Aspirin use and potential mechanisms for colorectal cancer prevention
    • Williams CS, Smalley W, and Dubois RN (1997) Aspirin use and potential mechanisms for colorectal cancer prevention. J Clin Investig 100:1325-1329.
    • (1997) J Clin Investig , vol.100 , pp. 1325-1329
    • Williams, C.S.1    Smalley, W.2    Dubois, R.N.3
  • 438
    • 0017770145 scopus 로고
    • Role of PG-mediated vasodilatation in inflammation
    • Williams TJ and Peck MJ (1977) Role of PG-mediated vasodilatation in inflammation. Nature (Lond) 270:530-532.
    • (1977) Nature (Lond) , vol.270 , pp. 530-532
    • Williams, T.J.1    Peck, M.J.2
  • 440
    • 0032171420 scopus 로고    scopus 로고
    • Chemical biology of NO: Insights into regulatory, cytotoxic and cytoprotective mechanisms of NO
    • Wink DA and Mitchell JB (1998) Chemical biology of NO: insights into regulatory, cytotoxic and cytoprotective mechanisms of NO. Free Radic Biol Med 25:434-456.
    • (1998) Free Radic Biol Med , vol.25 , pp. 434-456
    • Wink, D.A.1    Mitchell, J.B.2
  • 441
    • 0031034605 scopus 로고    scopus 로고
    • NO and NO synthase: Biology, pathology, localization
    • Wolf G (1997) NO and NO synthase: biology, pathology, localization. Histol Histopathol 12:251-261.
    • (1997) Histol Histopathol , vol.12 , pp. 251-261
    • Wolf, G.1
  • 442
    • 0033577982 scopus 로고    scopus 로고
    • Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs
    • Wolfe MM, Lichtenstein DR, and Singh G (1999) Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs. N Engl J Med 340:1888-1899.
    • (1999) N Engl J Med , vol.340 , pp. 1888-1899
    • Wolfe, M.M.1    Lichtenstein, D.R.2    Singh, G.3
  • 443
    • 0028077685 scopus 로고
    • The inhibition of the constitutive bovine endothelial nitric oxide synthase by imidazole and indazole agents
    • Wolff DJ, Lubeskie A, and Umansky S (1994) The inhibition of the constitutive bovine endothelial nitric oxide synthase by imidazole and indazole agents. Arch Biochem Biophys 314:360-366.
    • (1994) Arch Biochem Biophys , vol.314 , pp. 360-366
    • Wolff, D.J.1    Lubeskie, A.2    Umansky, S.3
  • 444
    • 0029443008 scopus 로고
    • Inducible COX and NO synthase
    • Wu KK (1995) Inducible COX and NO synthase. Adv Pharmacol 33:179-207.
    • (1995) Adv Pharmacol , vol.33 , pp. 179-207
    • Wu, K.K.1
  • 446
    • 0025754779 scopus 로고
    • Expression of a mitogen-responsive gene encoding PG synthase is regulated by mRNA splicing
    • Xie W, Chipman JG, Robertson DL, Erikson RL, and Simmons DL (1991) Expression of a mitogen-responsive gene encoding PG synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 88:2692-2696.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 2692-2696
    • Xie, W.1    Chipman, J.G.2    Robertson, D.L.3    Erikson, R.L.4    Simmons, D.L.5
  • 448
    • 0034769601 scopus 로고    scopus 로고
    • Effects of S-2474, a novel nonsteroidal anti-inflammatory drug, on amyloid beta protein-induced neuronal cell death
    • Yagami T, Ueda K, Asakura K, Sakaeda T, Kuroda T, Hata S, Kambayashi Y, and Fujimoto M (2001) Effects of S-2474, a novel nonsteroidal anti-inflammatory drug, on amyloid beta protein-induced neuronal cell death. Br J Pharmacol 134:673-681.
    • (2001) Br J Pharmacol , vol.134 , pp. 673-681
    • Yagami, T.1    Ueda, K.2    Asakura, K.3    Sakaeda, T.4    Kuroda, T.5    Hata, S.6    Kambayashi, Y.7    Fujimoto, M.8
  • 449
    • 0027290813 scopus 로고
    • Expression of a mitogen-inducible COX in brain neurons: Regulation by synaptic activity and glucocorticoids
    • Yamagata K, Andreasson KI, Kaufmann WE, Barnes CA, and Worley PF (1993) Expression of a mitogen-inducible COX in brain neurons: regulation by synaptic activity and glucocorticoids. Neuron 11:371-386.
    • (1993) Neuron , vol.11 , pp. 371-386
    • Yamagata, K.1    Andreasson, K.I.2    Kaufmann, W.E.3    Barnes, C.A.4    Worley, P.F.5
  • 450
    • 0030580417 scopus 로고    scopus 로고
    • Analysis of the effects of cyclooxygenase (COX)-1 and COX-2 in spinal nociceptive transmission using indomethacin, a non-selective COX inhibitor and NS-398, a COX-2 selective inhibitor
    • Yamamoto T and Nozaki-Taguchi N (1996) Analysis of the effects of cyclooxygenase (COX)-1 and COX-2 in spinal nociceptive transmission using indomethacin, a non-selective COX inhibitor and NS-398, a COX-2 selective inhibitor. Brain Res 739:104-110.
    • (1996) Brain Res , vol.739 , pp. 104-110
    • Yamamoto, T.1    Nozaki-Taguchi, N.2
  • 451
    • 0033694033 scopus 로고    scopus 로고
    • Cyclooxygenases in the central nervous system: Implications for treatment of neurological disorders
    • Yermakova A and O'Banion MK (2000) Cyclooxygenases in the central nervous system: implications for treatment of neurological disorders. Curr Pharm Des 6:1755-1776.
    • (2000) Curr Pharm des , vol.6 , pp. 1755-1776
    • Yermakova, A.1    O'Banion, M.K.2
  • 452
    • 0035693794 scopus 로고    scopus 로고
    • Downregulation of neuronal cyclooxygenase-2 expression in end stage Alzheimer's disease
    • Yermakova AV and O'Banion MK (2001) Downregulation of neuronal cyclooxygenase-2 expression in end stage Alzheimer's disease. Neurobiol Aging 22:823-836.
    • (2001) Neurobiol Aging , vol.22 , pp. 823-836
    • Yermakova, A.V.1    O'Banion, M.K.2
  • 453
    • 0032725481 scopus 로고    scopus 로고
    • Cyclooxygenase-1 in human Alzheimer and control brain: Quantitative analysis of expression by microglia and CA3 hippocampal neurons
    • Yermakova AV, Rollins J, Callahan LM, Rogers J, and O'Banion MK (1999) Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons. J Neuropathol Exp Neurol 58:1135-1146.
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 1135-1146
    • Yermakova, A.V.1    Rollins, J.2    Callahan, L.M.3    Rogers, J.4    O'Banion, M.K.5
  • 454
    • 0031863370 scopus 로고    scopus 로고
    • Comparison of antioxidant activities of aminoguanidine, methylguanidine and guanidine by luminol-enhanced chemiluminescence
    • Yildiz G, Demiryurek AT, Sahin-Erdemli I, and Kanzik I (1998) Comparison of antioxidant activities of aminoguanidine, methylguanidine and guanidine by luminol-enhanced chemiluminescence. Br J Pharmacol 124:905-910.
    • (1998) Br J Pharmacol , vol.124 , pp. 905-910
    • Yildiz, G.1    Demiryurek, A.T.2    Sahin-Erdemli, I.3    Kanzik, I.4
  • 455
    • 0028170047 scopus 로고
    • Alpha-guanidinoglutaric acid, an endogenous convulsant, as a novel nitric oxide synthase inhibitor
    • Yokoi I, Kabuto H, Habu H, and Mori A (1994) Alpha-guanidinoglutaric acid, an endogenous convulsant, as a novel nitric oxide synthase inhibitor. J Neurochem 63:1565-1567.
    • (1994) J Neurochem , vol.63 , pp. 1565-1567
    • Yokoi, I.1    Kabuto, H.2    Habu, H.3    Mori, A.4
  • 456
    • 0027233868 scopus 로고
    • Tumor necrosis factor downregulates an endothelial NO synthase mRNA by shortening its half-life
    • Yoshizumi M, Perrella MA, Burnett JC Jr, and Lee ME (1993) Tumor necrosis factor downregulates an endothelial NO synthase mRNA by shortening its half-life. Circ Res 73:205-209.
    • (1993) Circ Res , vol.73 , pp. 205-209
    • Yoshizumi, M.1    Perrella, M.A.2    Burnett Jr., J.C.3    Lee, M.E.4
  • 458
    • 0028219077 scopus 로고
    • Increase of an endogenous inhibitor of NO synthesis in serum of high cholesterol fed rabbits
    • Yu XJ, Li YJ, and Xiong Y (1994) Increase of an endogenous inhibitor of NO synthesis in serum of high cholesterol fed rabbits. Life Sci 54:753-758.
    • (1994) Life Sci , vol.54 , pp. 753-758
    • Yu, X.J.1    Li, Y.J.2    Xiong, Y.3
  • 459
    • 0029047323 scopus 로고
    • NO modulates the expression of monocyte chemoattractant protein 1 in cultured human endothelial cells
    • Zeiher AM, Fisslthaler B, Schray-Utz B, and Busse R (1995) NO modulates the expression of monocyte chemoattractant protein 1 in cultured human endothelial cells. Circ Res 76:980-986.
    • (1995) Circ Res , vol.76 , pp. 980-986
    • Zeiher, A.M.1    Fisslthaler, B.2    Schray-Utz, B.3    Busse, R.4
  • 460
    • 0030832496 scopus 로고    scopus 로고
    • Timing of administration of dexamethasone or the nitric oxide synthase inhibitor, nitro-L-arginine methyl ester, is critical for effective treatment of ischaemia-reperfusion injury to rat skeletal muscle
    • Zhang B, Knight KR, Dowsing B, Guida E, Phan LH, Hickey MJ, Morrison WA, and Stewart AG (1997) Timing of administration of dexamethasone or the nitric oxide synthase inhibitor, nitro-L-arginine methyl ester, is critical for effective treatment of ischaemia-reperfusion injury to rat skeletal muscle. Clin Sci (Lond) 93:167-174.
    • (1997) Clin Sci (Lond) , vol.93 , pp. 167-174
    • Zhang, B.1    Knight, K.R.2    Dowsing, B.3    Guida, E.4    Phan, L.H.5    Hickey, M.J.6    Morrison, W.A.7    Stewart, A.G.8
  • 461
    • 0028294246 scopus 로고
    • NO activation of poly(ADP-ribose) synthetase in neurotoxicity
    • Zhang J, Dawson VL, Dawson TM, and Snyder SH (1994) NO activation of poly(ADP-ribose) synthetase in neurotoxicity. Science (Wash DC) 263:687-689.
    • (1994) Science (Wash DC) , vol.263 , pp. 687-689
    • Zhang, J.1    Dawson, V.L.2    Dawson, T.M.3    Snyder, S.H.4
  • 463
    • 0034473913 scopus 로고    scopus 로고
    • Nitric oxide and angiogenesis
    • Ziche M and Morbidelli L (2000) Nitric oxide and angiogenesis. J Neurooncol 50: 139-148.
    • (2000) J Neurooncol , vol.50 , pp. 139-148
    • Ziche, M.1    Morbidelli, L.2
  • 466
    • 0029879266 scopus 로고    scopus 로고
    • Peroxynitrite formed by simultaneous generation of nitric oxide and superoxide selectively inhibits bovine aortic prostacyclin synthase
    • Zou MH and Ullrich V (1996) Peroxynitrite formed by simultaneous generation of nitric oxide and superoxide selectively inhibits bovine aortic prostacyclin synthase. FEBS Lett 382:101-104.
    • (1996) FEBS Lett , vol.382 , pp. 101-104
    • Zou, M.H.1    Ullrich, V.2


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