ARL 17477, a selective nitric oxide synthase inhibitor, with neuroprotective effects in animal models of global and focal cerebral ischaemia

Brain Research

Volumn 871, Issue 2, 2000, Pages 234-244

  O'Neill, Michael J ^a   Murray, Tracey K ^a   McCarty, Deborah R ^a   Hicks, Caroline A ^a   Dell, Colin P ^a   Patrick, Kelly E ^a   Ward, Mark A ^a   Osborne, David J ^a   Wiernicki, Todd R ^a   Roman, Carlos R ^a   Lodge, David ^a   Fleisch, Jerome H ^a   Singh, JaiPal ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

ARL 17477; Cerebral ischemia; Mongolian gerbil; Neuroprotection; Nitric oxide; Rat

Indexed keywords

ENDOTHELIN 1; N [4 [2 [[(3 CHLOROPHENYL)METHYL]AMINO]ETHYL]PHENYL] 2 THIOPHENECARBOXIMIDAMIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN ISCHEMIA; CONTROLLED STUDY; ENZYME INHIBITION; GERBIL; HUMAN; IN VITRO STUDY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

AMIDINES; ANIMALS; BRAIN ISCHEMIA; CELL LINE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENDOTHELIN-1; ENZYME INHIBITORS; GERBILLINAE; HUMANS; MALE; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE; RATS; REPERFUSION INJURY; TIME FACTORS;

EID: 0034698332     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02471-9     Document Type: Article

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