Nitric oxide and angiogenesis

Journal of Neuro-Oncology

Volumn 50, Issue 1-2, 2000, Pages 139-148

  Ziche, M ^a   Morbidelli, L ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

Angiogenesis; Cyclic GMP; Nitric oxide; Nitric oxide synthase; Tumor angiogenesis; Vascular endothelial growth factor

Indexed keywords

CYCLIC GMP; FIBROBLAST GROWTH FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; BRAIN EDEMA; BRAIN TUMOR; CAPILLARY ENDOTHELIUM; CELL DAMAGE; CELL DIFFERENTIATION; CELL GROWTH; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; INFLAMMATORY DISEASE; NONHUMAN; PROTEIN EXPRESSION; REVIEW; TUMOR GROWTH; VASCULAR DISEASE; VASODILATATION;

ANGIOGENESIS INHIBITORS; ANIMALS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HUMANS; ISOENZYMES; MAP KINASE SIGNALING SYSTEM; MICE; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RABBITS; RATS; SIGNAL TRANSDUCTION; STROMAL CELLS; TUMOR STEM CELLS; VASODILATION;

EID: 0034473913     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006431309841     Document Type: Review

References (69)

1. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
2. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
3. Nitric oxide synthases in mammals
4. New insights into the regulation of inducible nitric oxide synthesis
5. Molecular biological analysis of nitric oxide synthases
6. Cloning and characterization of murine endothelial constitutive nitric oxide synthase
7. Hypertension in mice lacking the gene for endothelial nitric oxide synthase
8. Impaired wound healing and angiogenesis in eNOS-deficient mice
9. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
10. Targeted disruption of the neuronal nitric oxide synthase gene
11. Nitric oxide: Physiology, pathophysiology, and pharmacology
12. Nitric oxide protects against the cytotoxic effects of reactive oxygen species
13. Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cells
14. Bi receptor involvement in the effect of bradykinin on venular endothelial cell proliferation and potentiation of FGF-2 effects
15. Nitric oxide is involved in the regulation of angiogenesis
16. Production of angiogenic activity by human monocytes requires an L-arginine/nitric oxide-synthase-dependent effector mechanism
17. Nitric oxide mediates angiogenesis induced in vivo by platelet-activating factor and tumor necrosis factor
18. Healing of chronic gastric ulcerations by L-arginine
19. Nitric oxide promotes DNA synthesis and cyclic GMP formation in endothelial cells from postcapillary venules
20. Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P
21. Substance P increases cyclic GMP levels on coronary postcapillary venular endothelial cells
22. Nitric oxide-synthase lies downstream of vascular endothelial growth factor but not basic fibroblast growth factor induced angiogenesis
23. Nitric oxide promotes proliferation and plasminogen activator production by coronary venular endothelium through endogenous bFGF
24. The biology of vascular endothelial growth factor
25. Vascular endothelial growth factor induces EDRF-dependent relaxation in coronary arteries
26. VEGF induces NO-dependent hyperpermeability in coronary venules
27. Nitric oxide mediates the mitogenic effect of VEGF on coronary venular endothelium
28. VEGE upregulates ecNOS message, protein, and NO production
29. Protein kinase C mediates vascular endothelial growth factor-induced raf-1 activation and proliferation in human endothelial cells
30. Nitric oxide is an upstream signal for vascular endothelial growth factor-induced extracellular signal-regulated kinases 1/2 activation in postcapillary endothelium
31. Reduction of infarct size by the NO donors sodium nitroprusside and spermine/NO after transient focal cerebral ischemia in rats
32. Expression of nitric oxide synthase in human central nervous system tumors
33. Nitric oxide synthase activity in human gynecological cancer
34. Nitric oxide synthase activity in human breast cancer
35. Role of nitric oxide in angiogenesis and tumor progression in head and neck cancer
36. Immunolocalization of inducible and constitutive nitric oxide synthases in human bladder cancer
37. Selective expression of inducible nitric oxide synthase in human prostate carcinoma
38. Role of nitric oxide in tumor progression: Lessons from human tumors
39. Selective inhibition of inducible nitric oxide synthase inhibits tumor growth in vivo. Studies with 1400 W, a novel inhibitor
40. Role of nitric oxide in angiogenesis and microcirculation in tumors
41. Role of nitric oxide in tumor angiogenesis
42. Middle T antigen-transformed endothelial cells exhibit an increased activity of nitric oxide synthase
43. NG-nitroL-arginine methyl ester, an inhibitor of nitric oxide synthesis, ameliorates interleukin 2-induced capillary leakage and reduces tumor growth in adenocarcinoma-bearing mice
44. Excessive production of NO in rat solid tumor and its implication in rapid tumor growth
45. Dexamethasone reduces vascular density and plasminogen activator activity in 9L rat brain tumors
46. Enhancement of tumor growth and vascular density by transfection of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells
47. Nitric oxide synthase inhibition by N(G)-nitro-L-arginine methyl ester inhibits tumor induced angiogenesis in mammary tumors
48. Nitric oxide production by mammary adenocarcinoma cells promotes tumor-cell invasiveness
49. Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells
50. Role of nitric oxide in mediation of macrophage cytotoxicity and apoptosis
51. Transfection with inducible nitric oxide synthase gene suppresses tumorgenicity and abrogates metastasis in K-1735 murine melanoma cells
52. Therapy of cancer metastasis by activation of the inducible nitric oxide synthase
53. Destruction of bystander cells by tumor cells transfected with inducible nitric oxide (NO) synthase gene
54. Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression
55. p53 and vascular endothelial growth factor regulate tumor growth of NOS-2 expressing human carcinoma cells
56. DNA deaminating ability and genotoxicity of nitric oxide and its progenitors
57. Nitric oxide (NO), a signaling molecule with a killer soul
58. Nitric oxide, superoxide and peroxynitrite: The good, the bad and the ugly
59. Differential expression of inducible nitric oxide synthase in human brain tumors
60. Inducible nitric oxide synthase in a human glioblastoma cell line
61. Expression of heme oxygenase and inducible nitric oxide synthase mRNA in human brain tumors
62. The expression of nitric oxide in human brain tumors and peritumoral areas
63. Endothelial nitric oxide synthase expression in tumor vasculature is correlated with malignancy in human supratentorial astrocytic tumors
64. Involvement of nitric oxide on the cytokine induced growth of glial cell
65. Selective sparing of a class of striatal neurons in Huntington's disease
66. Inflammation and glial responses in ischemic brain lesions
67. Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows
68. Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with L-arginine
69. Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions