Analysis of the effects of cyclooxygenase (COX)-1 and COX-2 in spinal nociceptive transmission using indomethacin, a non-selective COX inhibitor, and NS-398, a COX-2 selective inhibitor

Brain Research

Volumn 739, Issue 1-2, 1996, Pages 104-110

  Yamamoto, Tatsuo ^a   Nozaki Taguchi, Natsuko ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

cyclooxygenase 1; cyclooxygenase 2; formalin test; hot plate test; prostaglandin

Indexed keywords

INDOMETACIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN SYNTHASE;

ANALGESIA; ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CONTROLLED STUDY; HOT PLATE TEST; INTRAPERITONEAL DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; MALE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; INDOMETHACIN; INJECTIONS, SPINAL; ISOENZYMES; MALE; MEMBRANE PROTEINS; NITROBENZENES; PAIN; PAIN MEASUREMENT; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; SULFONAMIDES;

EID: 0030580417     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)00817-7     Document Type: Article

References (31)

1. [1] Breder, C.D., Smith, W.L., Raz, A., Masferrer, J., Seibert, K., Needleman, P. and Saper, C.B., Distribution and characterization of cyclooxygenase immunoreactivity in the ovine brain, J. Comp. Neurol., 322 (1992) 409-438.
2. [2] Catania, M.V., Hollingsworth, Z., Penney, J.B. and Young, A.B., Phospholipase A2 modulates different subtypes of excitatory amino acid receptors: autoradiographic evidence, J. Neurochem., 60 (1993) 236-245.
3. [3] Chapman, V. and Dickenson, A.H., The spinal and peripheral roles of bradykinin and prostaglandins in nociceptive processing in the rat, Eur. J. Pharmacol., 219 (1992) 427-433.
4. [4] Chen, J., Marsh, T., Zhang, J.S. and Graham, S.H., Expression of cyclooxygenase 2 in rat brain following kainate treatment, NeuroReport, 6 (1995) 245-248.
5. [5] Coderre, T.J. and Van Empel, I., The utility of excitatory amino acid (EAA) antagonists as analgesic agents. I. Comparison of the antinociceptive activity of various classes of EAA antagonists in mechanical, thermal and chemical nociceptive tests, Pain, 59 (1994) 345-352.
6. [6] Evans, M.S., Reid, K.H. and Sharp Jr., J.B., Dimethylsulfoxide (DMSO) blocks conduction in peripheral nerve C fibers: a possible mechanism of analgesia, Neurosci. Lett., 150 (1993) 145-148.
7. [7] Feng, L., Sun, W., Xia, Y., Tang, W.W., Chanmugam, P., Soyoola, E., Wilson, C.B. and Hwang, D., Cloning two isoforms of rat cyclooxygenase: differential regulation of their expression, Arch. Biochem. Biophys., 307 (1993) 361-368.
8. [8] Futaki, N., Arai, I., Hamasaka, Y., Takahashi, S., Higuchi, S. and Otomo, S., Selective inhibition of NS-398 on prostanoid production in inflamed tissue in rat carageenan-air-pouch inflammation, J. Pharm. Pharmacol., 45 (1993) 753-755.
9. [9] Futaki, N., Takahashi, S., Yokoyama, M., Arai, I., Higuchi, S. and Otomo, S., NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro, Prostaglandins, 47 (1994) 55-59.
10. [10] Futaki, N., Yoshikawa, K., Hamasaka, Y., Arai, I., Higuchi, S., Iizuka, H. and Otomo, S., NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions, Gen. Pharmac., 24 (1993) 105-110.
11. [11] Kantor, H.S. and Hampton, M., Indomethacin in submicromolar concentration inhibits cyclic AMP-dependent ptotein kinase, Nature, 276 (1978) 841-842.
12. [12] Kuraishi, Y., Hirota, N., Sato, Y., Hanashima, N., Takagi, H. and Satoh, M., Stimulus specificity of peripherally evoked substance P release from the rabbit dorsal horn in situ, Neuroscience, 30 (1989) 241-250.
13. [13] Kuraishi, Y., Hirota, N., Sato, Y., Hino, Y., Satoh, M. and Takagi, H., Evidence that substance P and somatostatin transmit separate information related to pain in the spinal dorsal horn, Brain Res., 325 (1985) 294-298.
14. [14] Malmberg, A.B. and Yaksh, T.L., Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the rat, J. Pharmacol. Exp. Ther., 263 (1992) 136-146.
15. 2 release in spinal cord slices: relative effect of cyclooxygenase inhibitors, Eur. J. Pharmacol., 271 (1994) 293-299.
16. 2 and amino acids evoked by paw formalin injection: a microdialysis study in unanesthetized rats, J. Neurosci., 15 (1995) 2768-2776.
17. [17] Malmberg, A.B. and Yaksh, T.L., The effect of morphine on formalin-evoked behaviour and spinal release of excitatory amino acids and prostaglandin E2 using microdialysis in conscious rats, Br. J. Pharmacol., 114 (1995) 1069-1075.
18. [18] Masferrer, J.L., Zweifel, B.S., Manning, P.T., Hauser, S.D., Leahy, K.M., Smith, W.G., Isakson, P.C. and Seibert, K., Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic, Proc. Natl. Acad. Sci. USA, 91 (1994) 3228-3232.
19. [19] McCormack, K., Non-steroidal anti-inflammatory drugs and spinal nociceptive processing, Pain, 59 (1994) 9-43.
20. 2α to conscious mice, Pain, 50 (1992) 223-229.
21. [21] Nishihara, I., Minami, T., Watanabe, Y., Ito, S. and Hayashi, O., Prostaglandin E2 stimulates glutamate release from synaptosomes of rat spinal cord, Neurosci. Lett., 196 (1995) 57-60.
22. [22] Planas, A.M., Soriano, M.A., Rodríguez-Farré, E. and Ferrer, I., Induction of cyclooxygenase-2 mRNA and protein following transient focal ischemia in the rat brain, Neurosci. Lett., 200 (1995) 187-190.
23. [23] Seibert, K., Zhang, Y., Leahy, K., Hauser, S., Masferrer, J., Perkins, W., Lee, L. and Isakson, P., Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain, Proc. Natl. Acad. Sci. USA, 91 (1994) 12013-12017.
24. [24] Smith, W.L., Marnett, L.J. and Dewitt, D.C., Prostaglandin and thromboxane biosynthesis, Pharmacol. Ther., 49 (1991) 153-179.
25. [25] Tiseo, P.J. and Inturrisi, C.E., Attenuation and reversal of morphine tolerance by the competitive N-methyl-D-aspartate receptor antagonist, LY274614, J. Pharmacol. Exp. Ther., 264 (1993) 1090-1096.
26. 2α to conscious mice, Brain Res., 510 (1990) 26-32.
27. [27] Wheeler-Aceto, H., Porreca, F. and Cowan A., The rat paw formalin test: comparison of noxious agents, Pain, 40 (1990) 229-238.
28. [28] White, D.M., Mechanism of prostaglandin E2-induced substance P release from cultured sensory neurons, Neuroscience, 70 (1996) 561-565.
29. [29] Yaksh, T.L. and Rudy, T.A., Chronic catheterization of the spinal subarachnoid space, Physiol. Behav., 17 (1976) 1031-1036.
30. [30] Yamamoto, T. and Nozaki-Taguchi, N., Zinc protoporphyrin IX, an inhibitor of the enzyme that produces carbon monoxide, blocks spinal nociceptive transmission evoked by formalin injection in the rat, Brain Res., 704 (1995) 256-262.
31. [31] Yamamoto, T., Shimoyama, N., Asano, H. and Mizuguchi, T., Analysis of the role of endothelin-A and endothelin-B receptors on nociceptive information transmission in the spinal cord with FR139317, an endothelin-A receptor antagonist, and Sarafotoxin S6c, an endothelin-B receptor agonist, J. Pharmacol. Exp. Ther., 271 (1994) 156-163.