I. Physiological chemistry of nitric oxide and its metabolites: Implications in inflammation

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 276, Issue 2 39-2, 1999, Pages

  Grisham, Matthew B ^a   Jourd'heuil, David ^a   Wink, David A ^b  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Arthritis; Cancer; Colitis; Free radicals; Leukocytes; Superoxide

Indexed keywords

NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; METAL; OXYGEN;

ARTHRITIS; CANCER; COLITIS; INFLAMMATION; INFLAMMATORY CELL; LEUKOCYTE; LIPID PEROXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; TISSUE INJURY; CHEMISTRY; HUMAN; METABOLISM; PHYSICAL CHEMISTRY; PHYSIOLOGY;

CHEMISTRY, PHYSICAL; HUMANS; METALS; NITRIC OXIDE; OXIDATIVE STRESS; OXYGEN;

EID: 0032910873     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1999.276.2.g315     Document Type: Review

References (27)

1. Beckman, J. S., W. H. Koppenol. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am. J. Physiol. 271 (Cell Physiol. 40): C1424-C1437, 1996.
2. Eiserich, J. P., M. Hristova, C. E. Cross, A. D. Jones, B. A. Freeman, B. Halliwell, and A. van der Vliet. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 391: 393-397, 1998.
3. Gow, A. J., and J. S. Stamler. Reactions between nitric oxide and haemoglobin under physiological conditions. Nature 391: 169-173, 1998.
4. Granger, D. N., and P. Kubes. Nitric oxide as anti-inflammatory agent. Methods Enzymol. 369: 434-442, 1996.
5. Grisham, M. B., D. N. Granger, D. Neil, and D. J. Lefer. Modulation of leukocyte-endothelial interactions by reactive metabolites of oxygen and nitrogen: relevance to ischemic heart disease. Free Radic. Biol. Med. 25: 404-433, 1998.
6. Hierholzer, C., B. Harbrecht, J. M. Menezes, J. Kane, J. MacMicking, C. F. Nathan, A. B. Peitzman, T. R. Billiar, and D. J. Tweardy. Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock. J. Exp. Med. 187: 917-928, 1998.
7. Ignarro, L. J. Biosynthesis and metabolism of endotheliumderived nitric oxide. Annu. Rev. Pharmacol. Toxicol. 30: 535-560, 1990.
8. Jourd'heuil, D., L. Mills, A. M. Miles, and M. B. Grisham. Effect of nitric oxide on hemoprotein-catalyzed oxidative reactions. Nitric Oxide 2: 37-44, 1998.
9. Kanner, J., S. Harel, and R. Granit. Nitric oxide as an antioxidant. Arch. Biochem. Biophys. 289: 130-136, 1991.
10. Lander, H. M., A. J. Milbank, J. M. Tauras, D. P. Hajjar, B. L. Hempstead, G. D. Schwartz, R. T. Kraemer, U. A. Mirza, B. T. Chait, S. C. Burk, and C. Quillia. Redox regulation of cell signaling. Nature 381: 380-381, 1996.
11. 2 within the hydrophobic interior of biological membranes. Proc. Natl. Acad. Sci. USA 95: 2175-2179, 1998.
12. Loscalzo, J., and G. Welch. Nitric oxide and its role in the cardiovascular system. Prog. Cardiovasc. Dis. 38: 87-104, 1995.
13. Miles, A. M., D. S. Bohle, P. A. Glassbrenner, B. Hansert, D. A. Wink, and M. B. Grisham. Modulation of superoxide-dependent oxidation and hydroxylation reactions by nitric oxide. J. Biol. Chem. 271: 40-47, 1996.
14. Moncada, S., R. M. J. Palmer, and E. A. Higgs. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43: 109-142, 1991.
15. Nathan, C. Inducible nitric oxide synthase: what difference does it make? J. Clin. Invest. 100: 2417-2423, 1997.
16. Padmaja, S., and R. E. Huie. The reaction of nitric oxide with organic peroxyl radicals. Biochem. Biophys. Res. Commun. 195: 539-544, 1993.
17. Palombella, V. J., E. M. Conner, J. W. Fuseler, A. Destree, J. M. Davis, F. S. Laroux, R. E. Wolf, J. Huang, S. Brand, P. J. Elliott, D. Lazarus, T. McCormack, L. Parent, R. Stein, J. Adams, and M. B. Grisham. Role of the proteasome and NF-κB in streptococcal cell wall-induced polyarthritis. Proc Natl Acad Sci. USA In press.
18. Pfeiffer, S., A. C. F. Gorren, K. Schmidt, E. R. Werner, B. Hansert, D. S. Bohle, and B. Mayer. Metabolic fate of peroxynitrite in aqueous solution. Reaction with nitric oxide and pH-dependent decomposition to nitrite and oxygen in a 2:1 stoichiometry. J. Biol. Chem. 272: 3465-3470, 1997.
19. Pfeiffer, S., and B. Mayer. Lack of tyrosine nitration by peroxynitrite generated at physiological pH. J Biol Chem. 273: 27280-27285, 1998.
20. Pryor, W. A., and G. L. Squadrito. The chemistry of peroxynitrite and peroxynitrous acid: products from the reaction of nitric oxide with superoxide. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L699-L721, 1995.
21. Rubbo, H., R. Radi, M. Trujillo, R. Telleri, B. Kalyanaraman, S. Barnes, M. Kirk, and A. Freeman. Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. J. Biol. Chem. 269: 26066-26075, 1994.
22. Salvemini, D., T. P. Misko, J. L. Masferrer, K. Seibert, M. G. Currie, and P. Needleman. Nitric oxide activates cyclooxygenase enzymes. Proc. Natl. Acad. Sci. USA 90: 7240-7244, 1993.
23. Stamler, J. S. Redox signaling: nitrosylation and related target interactions of nitric oxide. Cell 78: 931-936, 1994.
24. Stamler, J. S., L. Jia, J. P. Eu, T. J. McMahon, I. T. Demchenko, J. Bonaventura, K. Gernert, and C. A. Piantadosi. Blood flow regulation by S-nitrosohemoglobin in the physiological oxygen gradient. Science 276: 2034-2037, 1997.
25. Tamir, S., and S. R. Tannenbaum. The role of nitric oxide in the carcinogenic process. Biochim. Biophys. Acta 1288: F31-F36, 1996.
26. Wink, D. A., J. A. Cook, S. Kim, Y. Vodovotz, R. Pacelli, M. C. Kirshna, A. Russo, J. B. Mitchell, D. Jourd'heuil, A. M. Miles, and M. B. Grisham. Superoxide modulates the oxidation and nitrosation of thiols by nitric oxide derived reactive intermediates. J. Biol. Chem. 272: 11147-11151, 1997.
27. Wink, D. A., and J. B. Mitchell. The chemical biology of nitric oxide: insights into regulatory, cytotoxic and cytoprotective mechanisms of nitric oxide. Free Radic. Biol. Med. 25: 434-456, 1998.