Expression of cyclooxygenase-1 and -2 in normal and glaucomatous human eyes

Investigative Ophthalmology and Visual Science

Volumn 42, Issue 11, 2001, Pages 2616-2624

  Maihofner C ^a   Schlotzer Schrehardt U ^a   Guhring H ^a   Ulrich Zeilhofer, H ^a   Naumann, G O H ^a   Pahl, A ^a   Mardin, C ^a   Tamm, E R ^a   Brune, K ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2;

ARTICLE; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENZYME LOCALIZATION; HUMAN; HUMAN TISSUE; IMMUNOELECTRON MICROSCOPY; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; NUCLEOTIDE SEQUENCE; OPEN ANGLE GLAUCOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION;

ADULT; AGED; AGED, 80 AND OVER; AQUEOUS HUMOR; BLOTTING, WESTERN; CILIARY BODY; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DINOPROSTONE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GLAUCOMA, ANGLE-CLOSURE; GLAUCOMA, OPEN-ANGLE; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; MICROSCOPY, IMMUNOELECTRON; MIDDLE AGED; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER;

EID: 0034793217     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Number of people with glaucoma worldwide
2. Glaucoma
3. Localization of a locus (GLC1B) for adult-onset primary open angle glaucoma to the 2cen-q13 region
4. Identification of a gene that causes primary open angle glaucoma
5. Clinical features associated with mutations in the chromosome 1 open-angle glaucoma gene (GLC1A)
6. Corticosteroid-induced glaucoma
7. Risk of ocular hypertension or open-angle glaucoma in elderly patients on oral glucocorticoids
8. Endogenous glucocorticoids regulate an inducible cyclooxygenase enzyme
9. The ocular hypotensive effects and side effects of prostaglandins on the eyes of experimental animals
10. Aqueous humor dynamics: How PGF2 alpha lowers intraocular pressure
11. Latanoprost: Two years' experience of its use in the United Kingdom
12. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
13. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
14. Cyclooxygenases 1 and 2
15. Up-regulation of cyclooxygenase-2 mRNA in the rat spinal cord following peripheral inflammation
16. Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
17. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction
18. In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis
19. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2
20. Quantitative gene expression analysis in microdissected archival formalin-fixed and paraffin-embedded tumor tissue
21. Optimization of the isolation and amplification of RNA from formalin-fixed, paraffin-embedded tissue: The Armed Forces Institute of Pathology experience and literature review
22. Hydrocortisone-induced DNA endoreplication in human trabecular cells in vitro
23. Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product
24. Gene structure and properties of MYOC, an olfactomedin-related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cells
25. A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: Molecular cloning, tissue expression, and chromosomal mapping
26. Modulation of myocilin/TIGR expression in human trabecular meshwork
27. Clinical measurements of aqueous outflow
28. Further studies on facility of flow through the trabecular meshwork
29. Experimental aqueous perfusion in enucleated human eyes
30. Effect of corticosteroids on intraocular pressure and fluid dynamics
31. Cortisone et tension oculaire
32. Corticosteroid glaucoma
33. Corticosteroids and functions in the anterior segment of the eye
34. Glucocorticoid-induced formation of cross-linked actin networks in cultured human trabecular meshwork cells
35. EP3, but not EP2, FP, or TP prostanoid-receptor stimulation may reduce intraocular pressure
36. Molecular characterization and ocular hypotensive properties of the prostanoid EP2 receptor
37. Effect of 8-iso prostaglandin E2 on aqueous humor dynamics in monkeys
38. Effects on intraocular pressure and side effects of 0.005% latanoprost applied once daily, evening or morning: A comparison with timolol
39. Comparison of latanoprost and timolol in patients with ocular hypertension and glaucoma: A six-month masked, multicenter trial in the United States
40. Studies on the ocular hypotensive effects of prostaglandin F2 alpha ester prodrugs and receptor selective prostaglandin analogs
41. Localisation of prostaglandin F2 alpha and E2 binding sites in the human eye
42. Localization of the prostaglandin F2 alpha receptor messenger RNA and protein in the cynomolgus monkey eye
43. Prostaglandin F2 alpha and its analogs induce release of endogenous prostaglandins in iris and ciliary muscles isolated from cat and other mammalian species
44. Cyclooxygenase-1 and cyclooxygenase-2 in the human optic nerve head
45. Metabolism of arachidonic acid by isolated rabbit ciliary epithelium
46. Molecular mechanisms involved in the regulation of prostaglandin biosynthesis by glucocorticoids
47. Juvenile open angle glaucoma: Fine mapping of the TIGR gene to 1q24.3-q25.2 and mutation analysis
48. Assignment of the human prostaglandin-endoperoxide synthase 2 (PTGS2) gene to 1q25 by fluorescence in situ hybridization
49. The prostaglandin transporter is widely expressed in ocular tissues
50. The effects of intravitreally injected prostaglandin E1 on retinal function and their enhancement by a prostaglandin-transporter inhibitor
51. Effect of latanoprost on the extracellular matrix of the ciliary muscle: A study on cultured cells and tissue sections
52. Prostaglandins increase matrix metalloproteinase release from human ciliary smooth muscle cells
53. Prostaglandins increase proMMP-1 and proMMP-3 secretion by human ciliary smooth muscle cells