Induction of cyclooxygenase-2 expression during HIV-1-infected monocyte-derived macrophage and human brain microvascular endothelial cell interactions

Journal of Leukocyte Biology

Volumn 68, Issue 3, 2000, Pages 423-428

  Pereira, C F ^a   Boven, L A ^a   Middel, J ^a   Verhoef, J ^a   Nottet, H S L M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Cytokines; Eicosanoids; HIV 1 associated dementia; In vitro cocultures; Reverse transcriptase polymerase chain reaction; Western blot

Indexed keywords

CYCLOOXYGENASE 2; CYTOKINE; ICOSANOID; INTERLEUKIN 1BETA; MESSENGER RNA;

ARTICLE; CELL INTERACTION; DEMENTIA; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOBLOTTING; MACROPHAGE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS INFECTION;

AIDS DEMENTIA COMPLEX; BRAIN; CELL COMMUNICATION; COCULTURE TECHNIQUES; CYCLOOXYGENASE 2; ENDOTHELIUM, VASCULAR; HIV-1; HUMANS; INTERLEUKIN-1; ISOENZYMES; MACROPHAGES; MEMBRANE PROTEINS; MONOCYTES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RNA, MESSENGER; UP-REGULATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0033637536     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Unraveling the neuroimmune mechanisms for the HIV-1-associated cognitive/motor complex
2. The effects of human immunodeficiency virus in the central nervous system
3. Cellular aspects of HIV-1 infection of macrophages leading to neuronal dysfunction in in vitro models for HIV-1 encephalitis
4. Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain
5. Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: Implications for recruitment of leukocytes into brain and lymph nodes
6. Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia
7. Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia
8. Cytokine expression in the brain during the acquired immunodeficiency syndrome
9. Induction of nitric oxide synthase activity in human astrocytes by interleukin-1 beta and interferon-gamma
10. -) regulatory pathways
11. Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide
12. Proinflammatory cytokines regulate cyclooxygenase-2 mRNA expression in human macrophages
13. Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: A possible site of prostaglandin synthesis responsible for fever
14. Lipid mediators of hypersensitivity and inflammation
15. HIV-1 gp120-induced apoptosis in the rat neocortex involves enhanced expression of cyclo-oxygenase type 2 (COX-2)
16. Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage
17. Expression of a mitogen-inducible cyclooxygenase in brain neurons: Regulation by synaptic activity and glucocorticoids
18. Cyclooxygenase-2 induction in cerebral cortex: An intracellular response to synaptic excitation
19. Involvement of cyclooxygenase-2 in LPS-induced fever and regulation of its mRNA by LPS in the rat brain
20. Cyclooxygenases-1 and -2 are differentially localized to microglia and endothelium in rat EAE and glioma
21. Cyclooxygenase 2 RNA message abundance, stability, and hypervariability in sporadic Alzheimer neocortex
22. Effect of acute systemic inflammatory response and cytokines on the transcription of the genes encoding cyclooxygenase enzymes (COX-1 and COX-2) in the rat brain
23. Cyclooxygenase-2 is induced globally in infarcted human brain
24. Elevated central nervous system prostaglandins in human immunodeficiency virus-associated dementia
25. Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: Implications for the neuropathogenesis of HIV disease
26. Interactions between macrophages and brain microvascular endothelial cells: Role in pathogenesis of HIV-1 infection and blood-brain barrier function
27. Increased peroxynitrite activity in AIDS dementia complex: Implications for the neuropathogenesis of HIV-1 infection
28. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
29. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
30. Prostacyclin synthesis induced in vascular cells by interleukin-1
31. Human cyclooxygenase-2 cDNA
32. Human immunodeficiency virus glycoprotein (gp120) induction of monocyte arachidonic acid metabolites and interleukin 1
33. Leukotrienes increase blood-brain barrier permeability following intraparenchymal injections in rats
34. Paf-acether (platelet-activating factor) increases microvascular permeability and affects endothelium-granulocyte interaction in microvascular beds
35. Nitric oxide and prostaglandin E2 formation parallels blood-brain barrier disruption in an experimental rat model of bacterial meningitis
36. cAMP mediates IL-1-induced lymphocyte penetration through endothelial monolayers
37. Activation of protein kinases A and C increase lymphocyte penetration through endothelial monolayers
38. Recombinant human interleukin-1 induces meningitis and blood-brain barrier injury in the rat. Characterization and comparison with tumor necrosis factor
39. Mediation of inflammation by encephalitogenic cells: Interferon gamma induction of nitric oxide synthase and cyclooxygenase 2
40. Interferon-gamma reduces cyclooxygenase-2-mediated prostaglandin E2 production from primary mouse astrocytes independent of nitric oxide formation
41. Dissociation of IL-1 beta synthesis and secretion in human blood monocytes stimulated with bacterial cell wall products
42. Inflammatory agonists induce cyclooxygenase type 2 expression by human neutrophils
43. Specific NF-kappaB blockade selectively inhibits tumour necrosis factor-alpha-induced COX-2 but not constitutive COX-1 gene expression in HT-29 cells
44. CD40 engagement up-regulates cyclooxygenase-2 expression and prostaglandin E2 production in human lung fibroblasts