-
1
-
-
1542348477
-
Cancer statistics, 2004
-
A. Jemal, R.C. Tiwari, T. Murray, A. Ghafoor, A. Samuels, E. Ward, E.J. Feuer, M.J. Thun Cancer statistics, 2004 CA Cancer J Clin 54 2004 8 29
-
(2004)
CA Cancer J Clin
, vol.54
, pp. 8-29
-
-
Jemal, A.1
Tiwari, R.C.2
Murray, T.3
Ghafoor, A.4
Samuels, A.5
Ward, E.6
Feuer, E.J.7
Thun, M.J.8
-
2
-
-
0035020633
-
Pancreatic intraepithelial neoplasia: A new nomenclature and classification system for pancreatic duct lesions
-
R.H. Hruban, N.V. Adsay, J. Albores-Saavedra, C. Compton, E.S. Garrett, S.N. Goodman, S.E. Kern, D.S. Klimstra, G. Kloppel, D.S. Longnecker, J. Luttges, G.J. Offerhaus Pancreatic intraepithelial neoplasia a new nomenclature and classification system for pancreatic duct lesions Am J Surg Pathol 25 2001 579 586
-
(2001)
Am J Surg Pathol
, vol.25
, pp. 579-586
-
-
Hruban, R.H.1
Adsay, N.V.2
Albores-Saavedra, J.3
Compton, C.4
Garrett, E.S.5
Goodman, S.N.6
Kern, S.E.7
Klimstra, D.S.8
Kloppel, G.9
Longnecker, D.S.10
Luttges, J.11
Offerhaus, G.J.12
-
4
-
-
0016705111
-
Morphological patterns of primary nonendocrine human pancreas carcinoma
-
A.L. Cubilla, P.J. Fitzgerald Morphological patterns of primary nonendocrine human pancreas carcinoma Cancer Res 35 1975 2234 2248
-
(1975)
Cancer Res
, vol.35
, pp. 2234-2248
-
-
Cubilla, A.L.1
Fitzgerald, P.J.2
-
5
-
-
0017156835
-
Morphological lesions associated with human primary invasive nonendocrine pancreas cancer
-
A.L. Cubilla, P.J. Fitzgerald Morphological lesions associated with human primary invasive nonendocrine pancreas cancer Cancer Res 36 1976 2690 2698
-
(1976)
Cancer Res
, vol.36
, pp. 2690-2698
-
-
Cubilla, A.L.1
Fitzgerald, P.J.2
-
6
-
-
0028081120
-
K-ras mutations in pancreatic ductal proliferative lesions
-
D.S. Klimstra, D.S. Longnecker K-ras mutations in pancreatic ductal proliferative lesions Am J Pathol 145 1994 1547 1550
-
(1994)
Am J Pathol
, vol.145
, pp. 1547-1550
-
-
Klimstra, D.S.1
Longnecker, D.S.2
-
7
-
-
3242744313
-
An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms
-
R.H. Hruban, K. Takaori, D.S. Klimstra, N.V. Adsay, J. Albores-Saavedra, A.V. Biankin, S.A. Biankin, C. Compton, N. Fukushima, T. Furukawa, M. Goggins, Y. Kato, G. Kloppel, D.S. Longnecker, J. Luttges, A. Maitra, G.J. Offerhaus, M. Shimizu, S. Yonezawa An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms Am J Surg Pathol 28 2004 977 987
-
(2004)
Am J Surg Pathol
, vol.28
, pp. 977-987
-
-
Hruban, R.H.1
Takaori, K.2
Klimstra, D.S.3
Adsay, N.V.4
Albores-Saavedra, J.5
Biankin, A.V.6
Biankin, S.A.7
Compton, C.8
Fukushima, N.9
Furukawa, T.10
Goggins, M.11
Kato, Y.12
Kloppel, G.13
Longnecker, D.S.14
Luttges, J.15
Maitra, A.16
Offerhaus, G.J.17
Shimizu, M.18
Yonezawa, S.19
-
9
-
-
0032807116
-
Familial pancreatic cancer
-
R.H. Hruban, G.M. Petersen, M. Goggins, A.C. Tersmette, G.J. Offerhaus, F. Falatko, C.J. Yeo, S.E. Kern Familial pancreatic cancer Ann Oncol 10 Suppl 4 1999 69 73
-
(1999)
Ann Oncol
, vol.10
, Issue.4 SUPPL.
, pp. 69-73
-
-
Hruban, R.H.1
Petersen, G.M.2
Goggins, M.3
Tersmette, A.C.4
Offerhaus, G.J.5
Falatko, F.6
Yeo, C.J.7
Kern, S.E.8
-
10
-
-
0036883940
-
Pancreatic cancer biology and genetics
-
N. Bardeesy, R.A. DePinho Pancreatic cancer biology and genetics Nat Rev Cancer 2 2002 897 909
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 897-909
-
-
Bardeesy, N.1
DePinho, R.A.2
-
13
-
-
0038013875
-
Senescence, apoptosis and therapy--cutting the lifelines of cancer
-
C.A. Schmitt Senescence, apoptosis and therapy--cutting the lifelines of cancer Nat Rev Cancer 3 2003 286 295
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 286-295
-
-
Schmitt, C.A.1
-
14
-
-
9244224723
-
Intrinsic tumour suppression
-
S.W. Lowe, E. Cepero, G. Evan Intrinsic tumour suppression Nature 432 2004 307 315
-
(2004)
Nature
, vol.432
, pp. 307-315
-
-
Lowe, S.W.1
Cepero, E.2
Evan, G.3
-
15
-
-
0024292722
-
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
-
C. Almoguera, D. Shibata, K. Forrester, J. Martin, N. Arnheim, M. Perucho Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes Cell 53 1988 549 554
-
(1988)
Cell
, vol.53
, pp. 549-554
-
-
Almoguera, C.1
Shibata, D.2
Forrester, K.3
Martin, J.4
Arnheim, N.5
Perucho, M.6
-
16
-
-
0029125820
-
K-ras mutation and pancreatic adenocarcinoma
-
C. Caldas, S.E. Kern K-ras mutation and pancreatic adenocarcinoma Int J Pancreatol 18 1995 1 6
-
(1995)
Int J Pancreatol
, vol.18
, pp. 1-6
-
-
Caldas, C.1
Kern, S.E.2
-
18
-
-
0032979931
-
Immunohistochemical evaluation of K-ras, p53, and HER-2/neu expression in hyperplastic, dysplastic, and carcinomatous lesions of the pancreas: Evidence for multistep carcinogenesis
-
S.K. Apple, J.R. Hecht, D.N. Lewin, S.A. Jahromi, W.W. Grody, R.K. Nieberg Immunohistochemical evaluation of K-ras, p53, and HER-2/neu expression in hyperplastic, dysplastic, and carcinomatous lesions of the pancreas evidence for multistep carcinogenesis Hum Pathol 30 1999 123 129
-
(1999)
Hum Pathol
, vol.30
, pp. 123-129
-
-
Apple, S.K.1
Hecht, J.R.2
Lewin, D.N.3
Jahromi, S.A.4
Grody, W.W.5
Nieberg, R.K.6
-
19
-
-
0034175984
-
Understanding Ras: 'it ain't over 'til it's over'
-
J.M. Shields, K. Pruitt, A. McFall, A. Shaub, C.J. Der Understanding Ras 'it ain't over 'til it's over' Trends Cell Biol 10 2000 147 154
-
(2000)
Trends Cell Biol
, vol.10
, pp. 147-154
-
-
Shields, J.M.1
Pruitt, K.2
McFall, A.3
Shaub, A.4
Der, C.J.5
-
20
-
-
0027232296
-
Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma
-
M. Tada, M. Omata, S. Kawai, H. Saisho, M. Ohto, R.K. Saiki, J.J. Sninsky Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma Cancer Res 53 1993 2472 2474
-
(1993)
Cancer Res
, vol.53
, pp. 2472-2474
-
-
Tada, M.1
Omata, M.2
Kawai, S.3
Saisho, H.4
Ohto, M.5
Saiki, R.K.6
Sninsky, J.J.7
-
21
-
-
0027502624
-
Frequent c-Ki-ras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation
-
A. Yanagisawa, K. Ohtake, K. Ohashi, M. Hori, T. Kitagawa, H. Sugano, Y. Kato Frequent c-Ki-ras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation Cancer Res 53 1993 953 956
-
(1993)
Cancer Res
, vol.53
, pp. 953-956
-
-
Yanagisawa, A.1
Ohtake, K.2
Ohashi, K.3
Hori, M.4
Kitagawa, T.5
Sugano, H.6
Kato, Y.7
-
22
-
-
0030050945
-
Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease
-
M. Tada, M. Ohashi, Y. Shiratori, T. Okudaira, Y. Komatsu, T. Kawabe, H. Yoshida, R. Machinami, K. Kishi, M. Omata Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease Gastroenterology 110 1996 227 231
-
(1996)
Gastroenterology
, vol.110
, pp. 227-231
-
-
Tada, M.1
Ohashi, M.2
Shiratori, Y.3
Okudaira, T.4
Komatsu, Y.5
Kawabe, T.6
Yoshida, H.7
Machinami, R.8
Kishi, K.9
Omata, M.10
-
23
-
-
0030988302
-
p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma
-
C.A. Moskaluk, R.H. Hruban, S.E. Kern p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma Cancer Res 57 1997 2140 2143
-
(1997)
Cancer Res
, vol.57
, pp. 2140-2143
-
-
Moskaluk, C.A.1
Hruban, R.H.2
Kern, S.E.3
-
24
-
-
0345099455
-
Cellular senescence, an unpopular yet trustworthy tumor suppressor mechanism
-
F. Ishikawa Cellular senescence, an unpopular yet trustworthy tumor suppressor mechanism Cancer Sci 94 2003 944 947
-
(2003)
Cancer Sci
, vol.94
, pp. 944-947
-
-
Ishikawa, F.1
-
25
-
-
0028361374
-
Regulation of two E2F-related genes in presenescent and senescent human fibroblasts
-
G.P. Dimri, E. Hara, J. Campisi Regulation of two E2F-related genes in presenescent and senescent human fibroblasts J Biol Chem 269 1994 16180 16186
-
(1994)
J Biol Chem
, vol.269
, pp. 16180-16186
-
-
Dimri, G.P.1
Hara, E.2
Campisi, J.3
-
26
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
G.P. Dimri, X. Lee, G. Basile, M. Acosta, G. Scott, C. Roskelley, E.E. Medrano, M. Linskens, I. Rubelj, O. Pereira-Smith A biomarker that identifies senescent human cells in culture and in aging skin in vivo Proc Natl Acad Sci U S A 92 1995 9363 9367
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
-
27
-
-
0029784745
-
Replicative senescence, aging and growth-regulatory transcription factors
-
G.P. Dimri, A. Testori, M. Acosta, J. Campisi Replicative senescence, aging and growth-regulatory transcription factors Biol Signals 5 1996 154 162
-
(1996)
Biol Signals
, vol.5
, pp. 154-162
-
-
Dimri, G.P.1
Testori, A.2
Acosta, M.3
Campisi, J.4
-
28
-
-
0037309326
-
Tumor suppression by Ink4a-Arf: Progress and puzzles
-
S.W. Lowe, C.J. Sherr Tumor suppression by Ink4a-Arf progress and puzzles Curr Opin Genet Dev 13 2003 77 83
-
(2003)
Curr Opin Genet Dev
, vol.13
, pp. 77-83
-
-
Lowe, S.W.1
Sherr, C.J.2
-
29
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
M. Serrano, A.W. Lin, M.E. McCurrach, D. Beach, S.W. Lowe Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a Cell 88 1997 593 602
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
30
-
-
0030728468
-
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
-
T. Kamijo, F. Zindy, M.F. Roussel, D.E. Quelle, J.R. Downing, R.A. Ashmun, G. Grosveld, C.J. Sherr Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF Cell 91 1997 649 659
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
31
-
-
0032504784
-
p19ARF links the tumour suppressor p53 to Ras
-
I. Palmero, C. Pantoja, M. Serrano p19ARF links the tumour suppressor p53 to Ras Nature 395 1998 125 126
-
(1998)
Nature
, vol.395
, pp. 125-126
-
-
Palmero, I.1
Pantoja, C.2
Serrano, M.3
-
32
-
-
0028059330
-
Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
-
C. Caldas, S.A. Hahn, L.T. da Costa, M.S. Redston, M. Schutte, A.B. Seymour, C.L. Weinstein, R.H. Hruban, C.J. Yeo, S.E. Kern Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma Nat Genet 8 1994 27 32
-
(1994)
Nat Genet
, vol.8
, pp. 27-32
-
-
Caldas, C.1
Hahn, S.A.2
Da Costa, L.T.3
Redston, M.S.4
Schutte, M.5
Seymour, A.B.6
Weinstein, C.L.7
Hruban, R.H.8
Yeo, C.J.9
Kern, S.E.10
-
33
-
-
14444284330
-
Tumor-suppressive pathways in pancreatic carcinoma
-
E. Rozenblum, M. Schutte, M. Goggins, S.A. Hahn, S. Panzer, M. Zahurak, S.N. Goodman, T.A. Sohn, R.H. Hruban, C.J. Yeo, S.E. Kern Tumor-suppressive pathways in pancreatic carcinoma Cancer Res 57 1997 1731 1734
-
(1997)
Cancer Res
, vol.57
, pp. 1731-1734
-
-
Rozenblum, E.1
Schutte, M.2
Goggins, M.3
Hahn, S.A.4
Panzer, S.5
Zahurak, M.6
Goodman, S.N.7
Sohn, T.A.8
Hruban, R.H.9
Yeo, C.J.10
Kern, S.E.11
-
34
-
-
16944367477
-
Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas
-
M. Schutte, R.H. Hruban, J. Geradts, R. Maynard, W. Hilgers, S.K. Rabindran, C.A. Moskaluk, S.A. Hahn, I. Schwarte-Waldhoff, W. Schmiegel, S.B. Baylin, S.E. Kern, J.G. Herman Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas Cancer Res 57 1997 3126 3130
-
(1997)
Cancer Res
, vol.57
, pp. 3126-3130
-
-
Schutte, M.1
Hruban, R.H.2
Geradts, J.3
Maynard, R.4
Hilgers, W.5
Rabindran, S.K.6
Moskaluk, C.A.7
Hahn, S.A.8
Schwarte-Waldhoff, I.9
Schmiegel, W.10
Baylin, S.B.11
Kern, S.E.12
Herman, J.G.13
-
35
-
-
0032532379
-
Inactivation of the p16 (INK4A) tumor-suppressor gene in pancreatic duct lesions: Loss of intranuclear expression
-
R.E. Wilentz, J. Geradts, R. Maynard, G.J. Offerhaus, M. Kang, M. Goggins, C.J. Yeo, S.E. Kern, R.H. Hruban Inactivation of the p16 (INK4A) tumor-suppressor gene in pancreatic duct lesions loss of intranuclear expression Cancer Res 58 1998 4740 4744
-
(1998)
Cancer Res
, vol.58
, pp. 4740-4744
-
-
Wilentz, R.E.1
Geradts, J.2
Maynard, R.3
Offerhaus, G.J.4
Kang, M.5
Goggins, M.6
Yeo, C.J.7
Kern, S.E.8
Hruban, R.H.9
-
36
-
-
0032900535
-
Mutation of the CDKN2A 5′ UTR creates an aberrant initiation codon and predisposes to melanoma
-
L. Liu, D. Dilworth, L. Gao, J. Monzon, A. Summers, N. Lassam, D. Hogg Mutation of the CDKN2A 5′ UTR creates an aberrant initiation codon and predisposes to melanoma Nat Genet 21 1999 128 132
-
(1999)
Nat Genet
, vol.21
, pp. 128-132
-
-
Liu, L.1
Dilworth, D.2
Gao, L.3
Monzon, J.4
Summers, A.5
Lassam, N.6
Hogg, D.7
-
37
-
-
0034051469
-
Patients with both pancreatic adenocarcinoma and melanoma may harbor germline CDKN2A mutations
-
G. Lal, L. Liu, D. Hogg, N.J. Lassam, M.S. Redston, S. Gallinger Patients with both pancreatic adenocarcinoma and melanoma may harbor germline CDKN2A mutations Genes Chromosomes Cancer 27 2000 358 361
-
(2000)
Genes Chromosomes Cancer
, vol.27
, pp. 358-361
-
-
Lal, G.1
Liu, L.2
Hogg, D.3
Lassam, N.J.4
Redston, M.S.5
Gallinger, S.6
-
38
-
-
0035170850
-
A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family
-
J.A. Randerson-Moor, M. Harland, S. Williams, D. Cuthbert-Heavens, E. Sheridan, J. Aveyard, K. Sibley, L. Whitaker, M. Knowles, J.N. Bishop, D.T. Bishop A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family Hum Mol Genet 10 2001 55 62
-
(2001)
Hum Mol Genet
, vol.10
, pp. 55-62
-
-
Randerson-Moor, J.A.1
Harland, M.2
Williams, S.3
Cuthbert-Heavens, D.4
Sheridan, E.5
Aveyard, J.6
Sibley, K.7
Whitaker, L.8
Knowles, M.9
Bishop, J.N.10
Bishop, D.T.11
-
39
-
-
0030477686
-
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
-
D.A. Alcorta, Y. Xiong, D. Phelps, G. Hannon, D. Beach, J.C. Barrett Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts Proc Natl Acad Sci U S A 93 1996 13742 13747
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 13742-13747
-
-
Alcorta, D.A.1
Xiong, Y.2
Phelps, D.3
Hannon, G.4
Beach, D.5
Barrett, J.C.6
-
40
-
-
0029670840
-
Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence
-
E. Hara, R. Smith, D. Parry, H. Tahara, S. Stone, G. Peters Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence Mol Cell Biol 16 1996 859 867
-
(1996)
Mol Cell Biol
, vol.16
, pp. 859-867
-
-
Hara, E.1
Smith, R.2
Parry, D.3
Tahara, H.4
Stone, S.5
Peters, G.6
-
41
-
-
0032496373
-
Features of replicative senescence induced by direct addition of antennapedia-p16INK4A fusion protein to human diploid fibroblasts
-
D. Kato, K. Miyazawa, M. Ruas, M. Starborg, I. Wada, T. Oka, T. Sakai, G. Peters, E. Hara Features of replicative senescence induced by direct addition of antennapedia-p16INK4A fusion protein to human diploid fibroblasts FEBS Lett 427 1998 203 208
-
(1998)
FEBS Lett
, vol.427
, pp. 203-208
-
-
Kato, D.1
Miyazawa, K.2
Ruas, M.3
Starborg, M.4
Wada, I.5
Oka, T.6
Sakai, T.7
Peters, G.8
Hara, E.9
-
42
-
-
0032510327
-
Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts
-
B.B. McConnell, M. Starborg, S. Brookes, G. Peters Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts Curr Biol 8 1998 351 354
-
(1998)
Curr Biol
, vol.8
, pp. 351-354
-
-
McConnell, B.B.1
Starborg, M.2
Brookes, S.3
Peters, G.4
-
43
-
-
0032190629
-
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
-
A.W. Lin, M. Barradas, J.C. Stone, L. van Aelst, M. Serrano, S.W. Lowe Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling Genes Dev 12 1998 3008 3019
-
(1998)
Genes Dev
, vol.12
, pp. 3008-3019
-
-
Lin, A.W.1
Barradas, M.2
Stone, J.C.3
Van Aelst, L.4
Serrano, M.5
Lowe, S.W.6
-
44
-
-
0032192153
-
Senescence of human fibroblasts induced by oncogenic Raf
-
J. Zhu, D. Woods, M. McMahon, J.M. Bishop Senescence of human fibroblasts induced by oncogenic Raf Genes Dev 12 1998 2997 3007
-
(1998)
Genes Dev
, vol.12
, pp. 2997-3007
-
-
Zhu, J.1
Woods, D.2
McMahon, M.3
Bishop, J.M.4
-
45
-
-
0036242247
-
Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence
-
W. Wang, J.X. Chen, R. Liao, Q. Deng, J.J. Zhou, S. Huang, P. Sun Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence Mol Cell Biol 22 2002 3389 3403
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3389-3403
-
-
Wang, W.1
Chen, J.X.2
Liao, R.3
Deng, Q.4
Zhou, J.J.5
Huang, S.6
Sun, P.7
-
46
-
-
0035931859
-
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
-
N. Ohtani, Z. Zebedee, T.J. Huot, J.A. Stinson, M. Sugimoto, Y. Ohashi, A.D. Sharrocks, G. Peters, E. Hara Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence Nature 409 2001 1067 1070
-
(2001)
Nature
, vol.409
, pp. 1067-1070
-
-
Ohtani, N.1
Zebedee, Z.2
Huot, T.J.3
Stinson, J.A.4
Sugimoto, M.5
Ohashi, Y.6
Sharrocks, A.D.7
Peters, G.8
Hara, E.9
-
48
-
-
0033635597
-
Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions
-
J.H. Dannenberg, A. van Rossum, L. Schuijff, H. te Riele Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions Genes Dev 14 2000 3051 3064
-
(2000)
Genes Dev
, vol.14
, pp. 3051-3064
-
-
Dannenberg, J.H.1
Van Rossum, A.2
Schuijff, L.3
Te Riele, H.4
-
49
-
-
0033637086
-
Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization
-
J. Sage, G.J. Mulligan, L.D. Attardi, A. Miller, S. Chen, B. Williams, E. Theodorou, T. Jacks Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization Genes Dev 14 2000 3037 3050
-
(2000)
Genes Dev
, vol.14
, pp. 3037-3050
-
-
Sage, J.1
Mulligan, G.J.2
Attardi, L.D.3
Miller, A.4
Chen, S.5
Williams, B.6
Theodorou, E.7
Jacks, T.8
-
50
-
-
0038342441
-
Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry
-
J. Sage, A.L. Miller, P.A. Perez-Mancera, J.M. Wysocki, T. Jacks Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry Nature 424 2003 223 228
-
(2003)
Nature
, vol.424
, pp. 223-228
-
-
Sage, J.1
Miller, A.L.2
Perez-Mancera, P.A.3
Wysocki, J.M.4
Jacks, T.5
-
51
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
M. Narita, S. Nunez, E. Heard, A.W. Lin, S.A. Hearn, D.L. Spector, G.J. Hannon, S.W. Lowe Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence Cell 113 2003 703 716
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
Lin, A.W.4
Hearn, S.A.5
Spector, D.L.6
Hannon, G.J.7
Lowe, S.W.8
-
53
-
-
0026334753
-
Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer
-
C.M. Barton, S.L. Staddon, C.M. Hughes, P.A. Hall, C. O'Sullivan, G. Kloppel, B. Theis, R.C. Russell, J. Neoptolemos, R.C. Williamson Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer Br J Cancer 64 1991 1076 1082
-
(1991)
Br J Cancer
, vol.64
, pp. 1076-1082
-
-
Barton, C.M.1
Staddon, S.L.2
Hughes, C.M.3
Hall, P.A.4
O'Sullivan, C.5
Kloppel, G.6
Theis, B.7
Russell, R.C.8
Neoptolemos, J.9
Williamson, R.C.10
-
54
-
-
0028152702
-
Expression of p53 protein in precursor lesions and adenocarcinoma of human pancreas
-
C.R. Boschman, S. Stryker, J.K. Reddy, M.S. Rao Expression of p53 protein in precursor lesions and adenocarcinoma of human pancreas Am J Pathol 145 1994 1291 1295
-
(1994)
Am J Pathol
, vol.145
, pp. 1291-1295
-
-
Boschman, C.R.1
Stryker, S.2
Reddy, J.K.3
Rao, M.S.4
-
55
-
-
0028305095
-
Overexpression of p53 protein in adenocarcinoma of the pancreas
-
J.A. DiGiuseppe, R.H. Hruban, S.N. Goodman, M. Polak, F.M. van den Berg, D.C. Allison, J.L. Cameron, G.J. Offerhaus Overexpression of p53 protein in adenocarcinoma of the pancreas Am J Clin Pathol 101 1994 684 688
-
(1994)
Am J Clin Pathol
, vol.101
, pp. 684-688
-
-
DiGiuseppe, J.A.1
Hruban, R.H.2
Goodman, S.N.3
Polak, M.4
Van Den Berg, F.M.5
Allison, D.C.6
Cameron, J.L.7
Offerhaus, G.J.8
-
56
-
-
0028308492
-
p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions
-
M.S. Redston, C. Caldas, A.B. Seymour, R.H. Hruban, L. da Costa, C.J. Yeo, S.E. Kern p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions Cancer Res 54 1994 3025 3033
-
(1994)
Cancer Res
, vol.54
, pp. 3025-3033
-
-
Redston, M.S.1
Caldas, C.2
Seymour, A.B.3
Hruban, R.H.4
Da Costa, L.5
Yeo, C.J.6
Kern, S.E.7
-
57
-
-
0033013980
-
Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts
-
G.H. Stein, L.F. Drullinger, A. Soulard, V. Dulic Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts Mol Cell Biol 19 1999 2019 2117
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2019-2117
-
-
Stein, G.H.1
Drullinger, L.F.2
Soulard, A.3
Dulic, V.4
-
58
-
-
0035942177
-
Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation
-
A.W. Lin, S.W. Lowe Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation Proc Natl Acad Sci U S A 98 2001 5025 5030
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5025-5030
-
-
Lin, A.W.1
Lowe, S.W.2
-
59
-
-
0036237039
-
Oncogenic ras and p53 cooperate to induce cellular senescence
-
G. Ferbeyre, E. de Stanchina, A.W. Lin, E. Querido, M.E. McCurrach, G.J. Hannon, S.W. Lowe Oncogenic ras and p53 cooperate to induce cellular senescence Mol Cell Biol 22 2002 3497 3508
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3497-3508
-
-
Ferbeyre, G.1
De Stanchina, E.2
Lin, A.W.3
Querido, E.4
McCurrach, M.E.5
Hannon, G.J.6
Lowe, S.W.7
-
60
-
-
0041966056
-
Reversal of human cellular senescence: Roles of the p53 and p16 pathways
-
C.M. Beausejour, A. Krtolica, F. Galimi, M. Narita, S.W. Lowe, P. Yaswen, J. Campisi Reversal of human cellular senescence roles of the p53 and p16 pathways EMBO J 22 2003 4212 4222
-
(2003)
EMBO J
, vol.22
, pp. 4212-4222
-
-
Beausejour, C.M.1
Krtolica, A.2
Galimi, F.3
Narita, M.4
Lowe, S.W.5
Yaswen, P.6
Campisi, J.7
-
61
-
-
0028342664
-
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
-
A. Noda, Y. Ning, S.F. Venable, O.M. Pereira-Smith, J.R. Smith Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen Exp Cell Res 211 1994 90 98
-
(1994)
Exp Cell Res
, vol.211
, pp. 90-98
-
-
Noda, A.1
Ning, Y.2
Venable, S.F.3
Pereira-Smith, O.M.4
Smith, J.R.5
-
62
-
-
0035893388
-
Overexpression of p21(WAF1/CIP1) is an early event in the development of pancreatic intraepithelial neoplasia
-
A.V. Biankin, J.G. Kench, A.L. Morey, C.S. Lee, S.A. Biankin, D.R. Head, T.B. Hugh, S.M. Henshall, R.L. Sutherland Overexpression of p21(WAF1/CIP1) is an early event in the development of pancreatic intraepithelial neoplasia Cancer Res 61 2001 8830 8837
-
(2001)
Cancer Res
, vol.61
, pp. 8830-8837
-
-
Biankin, A.V.1
Kench, J.G.2
Morey, A.L.3
Lee, C.S.4
Biankin, S.A.5
Head, D.R.6
Hugh, T.B.7
Henshall, S.M.8
Sutherland, R.L.9
-
63
-
-
0035487104
-
The INK4a/ARF network in tumour suppression
-
C.J. Sherr The INK4a/ARF network in tumour suppression Nat Rev Mol Cell Biol 2 2001 731 737
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 731-737
-
-
Sherr, C.J.1
-
64
-
-
0036841802
-
Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia
-
N.T. van Heek, A.K. Meeker, S.E. Kern, C.J. Yeo, K.D. Lillemoe, J.L. Cameron, G.J. Offerhaus, J.L. Hicks, R.E. Wilentz, M.G. Goggins, A.M. De Marzo, R.H. Hruban, A. Maitra Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia Am J Pathol 161 2002 1541 1547
-
(2002)
Am J Pathol
, vol.161
, pp. 1541-1547
-
-
Van Heek, N.T.1
Meeker, A.K.2
Kern, S.E.3
Yeo, C.J.4
Lillemoe, K.D.5
Cameron, J.L.6
Offerhaus, G.J.7
Hicks, J.L.8
Wilentz, R.E.9
Goggins, M.G.10
De Marzo, A.M.11
Hruban, R.H.12
Maitra, A.13
-
65
-
-
0026054961
-
A role for both RB and p53 in the regulation of human cellular senescence
-
J.W. Shay, O.M. Pereira-Smith, W.E. Wright A role for both RB and p53 in the regulation of human cellular senescence Exp Cell Res 196 1991 33 39
-
(1991)
Exp Cell Res
, vol.196
, pp. 33-39
-
-
Shay, J.W.1
Pereira-Smith, O.M.2
Wright, W.E.3
-
66
-
-
0037102234
-
Different telomere damage signaling pathways in human and mouse cells
-
A. Smogorzewska, T. de Lange Different telomere damage signaling pathways in human and mouse cells EMBO J 21 2002 4338 4348
-
(2002)
EMBO J
, vol.21
, pp. 4338-4348
-
-
Smogorzewska, A.1
De Lange, T.2
-
67
-
-
0035953550
-
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
-
L. Johnson, K. Mercer, D. Greenbaum, R.T. Bronson, D. Crowley, D.A. Tuveson, T. Jacks Somatic activation of the K-ras oncogene causes early onset lung cancer in mice Nature 410 2001 1111 1116
-
(2001)
Nature
, vol.410
, pp. 1111-1116
-
-
Johnson, L.1
Mercer, K.2
Greenbaum, D.3
Bronson, R.T.4
Crowley, D.5
Tuveson, D.A.6
Jacks, T.7
-
68
-
-
0041883654
-
Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context
-
C. Guerra, N. Mijimolle, A. Dhawahir, P. Dubus, M. Barradas, M. Serrano, V. Campuzano, M. Barbacid Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context Cancer Cell 4 2003 111 120
-
(2003)
Cancer Cell
, vol.4
, pp. 111-120
-
-
Guerra, C.1
Mijimolle, N.2
Dhawahir, A.3
Dubus, P.4
Barradas, M.5
Serrano, M.6
Campuzano, V.7
Barbacid, M.8
-
69
-
-
1642355129
-
Normal human fibroblasts are resistant to RAS-induced senescence
-
J.A. Benanti, D.A. Galloway Normal human fibroblasts are resistant to RAS-induced senescence Mol Cell Biol 24 2004 2842 2852
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2842-2852
-
-
Benanti, J.A.1
Galloway, D.A.2
-
70
-
-
11144356354
-
Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects
-
D.A. Tuveson, A.T. Shaw, N.A. Willis, D.P. Silver, E.L. Jackson, S. Chang, K.L. Mercer, R. Grochow, H. Hock, D. Crowley, S.R. Hingorani, T. Zaks, C. King, M.A. Jacobetz, L. Wang, R.T. Bronson, S.H. Orkin, R.A. DePinho, T. Jacks Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects Cancer Cell 5 2004 375 387
-
(2004)
Cancer Cell
, vol.5
, pp. 375-387
-
-
Tuveson, D.A.1
Shaw, A.T.2
Willis, N.A.3
Silver, D.P.4
Jackson, E.L.5
Chang, S.6
Mercer, K.L.7
Grochow, R.8
Hock, H.9
Crowley, D.10
Hingorani, S.R.11
Zaks, T.12
King, C.13
Jacobetz, M.A.14
Wang, L.15
Bronson, R.T.16
Orkin, S.H.17
DePinho, R.A.18
Jacks, T.19
-
71
-
-
85047694328
-
Cellular senescence in cancer treatment: Friend or foe?
-
P. Kahlem, B. Dorken, C.A. Schmitt Cellular senescence in cancer treatment friend or foe? J Clin Invest 113 2004 169 174
-
(2004)
J Clin Invest
, vol.113
, pp. 169-174
-
-
Kahlem, P.1
Dorken, B.2
Schmitt, C.A.3
-
72
-
-
0026642195
-
Induction of apoptosis in fibroblasts by c-myc protein
-
G.I. Evan, A.H. Wyllie, C.S. Gilbert, T.D. Littlewood, H. Land, M. Brooks, C.M. Waters, L.Z. Penn, D.C. Hancock Induction of apoptosis in fibroblasts by c-myc protein Cell 69 1992 119 128
-
(1992)
Cell
, vol.69
, pp. 119-128
-
-
Evan, G.I.1
Wyllie, A.H.2
Gilbert, C.S.3
Littlewood, T.D.4
Land, H.5
Brooks, M.6
Waters, C.M.7
Penn, L.Z.8
Hancock, D.C.9
-
73
-
-
0036547417
-
Death and anti-death: Tumour resistance to apoptosis
-
F.H. Igney, P.H. Krammer Death and anti-death tumour resistance to apoptosis Nat Rev Cancer 2 2002 277 288
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 277-288
-
-
Igney, F.H.1
Krammer, P.H.2
-
74
-
-
0034663829
-
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c
-
M.C. Wei, T. Lindsten, V.K. Mootha, S. Weiler, A. Gross, M. Ashiya, C.B. Thompson, S.J. Korsmeyer tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c Genes Dev 14 2000 2060 2071
-
(2000)
Genes Dev
, vol.14
, pp. 2060-2071
-
-
Wei, M.C.1
Lindsten, T.2
Mootha, V.K.3
Weiler, S.4
Gross, A.5
Ashiya, M.6
Thompson, C.B.7
Korsmeyer, S.J.8
-
75
-
-
0035229427
-
The mitochondrion in apoptosis: How Pandora's box opens
-
N. Zamzami, G. Kroemer The mitochondrion in apoptosis how Pandora's box opens Nat Rev Mol Cell Biol 2 2001 67 71
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 67-71
-
-
Zamzami, N.1
Kroemer, G.2
-
76
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
X. Luo, I. Budihardjo, H. Zou, C. Slaughter, X. Wang Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors Cell 94 1998 481 490
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
77
-
-
0034676268
-
Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis
-
S. Hinz, A. Trauzold, L. Boenicke, C. Sandberg, S. Beckmann, E. Bayer, H. Walczak, H. Kalthoff, H. Ungefroren Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis Oncogene 19 2000 5477 5486
-
(2000)
Oncogene
, vol.19
, pp. 5477-5486
-
-
Hinz, S.1
Trauzold, A.2
Boenicke, L.3
Sandberg, C.4
Beckmann, S.5
Bayer, E.6
Walczak, H.7
Kalthoff, H.8
Ungefroren, H.9
-
78
-
-
17944379442
-
CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells
-
A. Trauzold, H. Wermann, A. Arlt, S. Schutze, H. Schafer, S. Oestern, C. Roder, H. Ungefroren, E. Lampe, M. Heinrich, H. Walczak, H. Kalthoff CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells Oncogene 20 2001 4258 4269
-
(2001)
Oncogene
, vol.20
, pp. 4258-4269
-
-
Trauzold, A.1
Wermann, H.2
Arlt, A.3
Schutze, S.4
Schafer, H.5
Oestern, S.6
Roder, C.7
Ungefroren, H.8
Lampe, E.9
Heinrich, M.10
Walczak, H.11
Kalthoff, H.12
-
79
-
-
1142274315
-
Apoptosis in cancer--implications for therapy
-
H. Schulze-Bergkamen, P.H. Krammer Apoptosis in cancer--implications for therapy Semin Oncol 31 2004 90 119
-
(2004)
Semin Oncol
, vol.31
, pp. 90-119
-
-
Schulze-Bergkamen, H.1
Krammer, P.H.2
-
80
-
-
0037128667
-
Analysis of the cytochrome c-dependent apoptosis apparatus in cells from human pancreatic carcinoma
-
M.C. Gerhard, R.M. Schmid, G. Hacker Analysis of the cytochrome c-dependent apoptosis apparatus in cells from human pancreatic carcinoma Br J Cancer 86 2002 893 898
-
(2002)
Br J Cancer
, vol.86
, pp. 893-898
-
-
Gerhard, M.C.1
Schmid, R.M.2
Hacker, G.3
-
81
-
-
11844301338
-
Cell death pathways in pancreatitis and pancreatic cancer
-
A.S. Gukovskaya, S.J. Pandol Cell death pathways in pancreatitis and pancreatic cancer Pancreatology 4 2004 567 586
-
(2004)
Pancreatology
, vol.4
, pp. 567-586
-
-
Gukovskaya, A.S.1
Pandol, S.J.2
-
82
-
-
0034012799
-
Fas and Fas-ligand expression in human pancreatic cancer
-
M. Kornmann, T. Ishiwata, J. Kleeff, H.G. Beger, M. Korc Fas and Fas-ligand expression in human pancreatic cancer Ann Surg 231 2000 368 379
-
(2000)
Ann Surg
, vol.231
, pp. 368-379
-
-
Kornmann, M.1
Ishiwata, T.2
Kleeff, J.3
Beger, H.G.4
Korc, M.5
-
83
-
-
0034956807
-
Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death
-
S.M. Ibrahim, J. Ringel, C. Schmidt, B. Ringel, P. Muller, D. Koczan, H.J. Thiesen, M. Lohr Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death Pancreas 23 2001 72 79
-
(2001)
Pancreas
, vol.23
, pp. 72-79
-
-
Ibrahim, S.M.1
Ringel, J.2
Schmidt, C.3
Ringel, B.4
Muller, P.5
Koczan, D.6
Thiesen, H.J.7
Lohr, M.8
-
84
-
-
0038545700
-
Endogenous decoy receptor 3 blocks the growth inhibition signals mediated by Fas ligand in human pancreatic adenocarcinoma
-
S. Tsuji, R. Hosotani, S. Yonehara, T. Masui, S.S. Tulachan, S. Nakajima, H. Kobayashi, M. Koizumi, E. Toyoda, D. Ito, K. Kami, T. Mori, K. Fujimoto, R. Doi, M. Imamura Endogenous decoy receptor 3 blocks the growth inhibition signals mediated by Fas ligand in human pancreatic adenocarcinoma Int J Cancer 106 2003 17 25
-
(2003)
Int J Cancer
, vol.106
, pp. 17-25
-
-
Tsuji, S.1
Hosotani, R.2
Yonehara, S.3
Masui, T.4
Tulachan, S.S.5
Nakajima, S.6
Kobayashi, H.7
Koizumi, M.8
Toyoda, E.9
Ito, D.10
Kami, K.11
Mori, T.12
Fujimoto, K.13
Doi, R.14
Imamura, M.15
-
85
-
-
0035192884
-
FLICE-inhibitory proteins: Regulators of death receptor-mediated apoptosis
-
A. Krueger, S. Baumann, P.H. Krammer, S. Kirchhoff FLICE-inhibitory proteins regulators of death receptor-mediated apoptosis Mol Cell Biol 21 2001 8247 8254
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8247-8254
-
-
Krueger, A.1
Baumann, S.2
Krammer, P.H.3
Kirchhoff, S.4
-
86
-
-
0035258678
-
Human pancreatic cancer cells disable function of Fas receptors at several levels in Fas signal transduction pathway
-
A. Elnemr, T. Ohta, A. Yachie, M. Kayahara, H. Kitagawa, T. Fujimura, I. Ninomiya, S. Fushida, G.I. Nishimura, K. Shimizu, K. Miwa Human pancreatic cancer cells disable function of Fas receptors at several levels in Fas signal transduction pathway Int J Oncol 18 2001 311 316
-
(2001)
Int J Oncol
, vol.18
, pp. 311-316
-
-
Elnemr, A.1
Ohta, T.2
Yachie, A.3
Kayahara, M.4
Kitagawa, H.5
Fujimura, T.6
Ninomiya, I.7
Fushida, S.8
Nishimura, G.I.9
Shimizu, K.10
Miwa, K.11
-
87
-
-
0344440978
-
Multiple and synergistic deregulations of apoptosis-controlling genes in pancreatic carcinoma cells
-
A. Trauzold, S. Schmiedel, C. Roder, C. Tams, M. Christgen, S. Oestern, A. Arlt, S. Westphal, M. Kapischke, H. Ungefroren, H. Kalthoff Multiple and synergistic deregulations of apoptosis-controlling genes in pancreatic carcinoma cells Br J Cancer 89 2003 1714 1721
-
(2003)
Br J Cancer
, vol.89
, pp. 1714-1721
-
-
Trauzold, A.1
Schmiedel, S.2
Roder, C.3
Tams, C.4
Christgen, M.5
Oestern, S.6
Arlt, A.7
Westphal, S.8
Kapischke, M.9
Ungefroren, H.10
Kalthoff, H.11
-
88
-
-
0034858398
-
FAP-1 in pancreatic cancer cells: Functional and mechanistic studies on its inhibitory role in CD95-mediated apoptosis
-
H. Ungefroren, M.L. Kruse, A. Trauzold, S. Roeschmann, C. Roeder, A. Arlt, D. Henne-Bruns, H. Kalthoff FAP-1 in pancreatic cancer cells functional and mechanistic studies on its inhibitory role in CD95-mediated apoptosis J Cell Sci 114 2001 2735 2746
-
(2001)
J Cell Sci
, vol.114
, pp. 2735-2746
-
-
Ungefroren, H.1
Kruse, M.L.2
Trauzold, A.3
Roeschmann, S.4
Roeder, C.5
Arlt, A.6
Henne-Bruns, D.7
Kalthoff, H.8
-
89
-
-
20144387486
-
CD95 and TRAF2 promote invasiveness of pancreatic cancer cells
-
A. Trauzold, C. Roder, B. Sipos, K. Karsten, A. Arlt, P. Jiang, J.I. Martin-Subero, D. Siegmund, S. Muerkoster, L. Pagerols Raluy, R. Siebert, H. Wajant, H. Kalthoff CD95 and TRAF2 promote invasiveness of pancreatic cancer cells FASEB J 19 2005 620 622
-
(2005)
FASEB J
, vol.19
, pp. 620-622
-
-
Trauzold, A.1
Roder, C.2
Sipos, B.3
Karsten, K.4
Arlt, A.5
Jiang, P.6
Martin-Subero, J.I.7
Siegmund, D.8
Muerkoster, S.9
Pagerols Raluy, L.10
Siebert, R.11
Wajant, H.12
Kalthoff, H.13
-
90
-
-
0034869384
-
Bcl-2 expression in pancreas development and pancreatic cancer progression
-
D. Campani, I. Esposito, U. Boggi, D. Cecchetti, M. Menicagli, F. De Negri, L. Colizzi, M. Del Chiaro, F. Mosca, G. Fornaciari, G. Bevilacqua Bcl-2 expression in pancreas development and pancreatic cancer progression J Pathol 194 2001 444 450
-
(2001)
J Pathol
, vol.194
, pp. 444-450
-
-
Campani, D.1
Esposito, I.2
Boggi, U.3
Cecchetti, D.4
Menicagli, M.5
De Negri, F.6
Colizzi, L.7
Del Chiaro, M.8
Mosca, F.9
Fornaciari, G.10
Bevilacqua, G.11
-
91
-
-
0035554145
-
Detailed tissue expression of bcl-2, bax, bak and bcl-x in the normal human pancreas and in chronic pancreatitis, ampullary and pancreatic ductal adenocarcinomas
-
J.D. Evans, P.A. Cornford, A. Dodson, W. Greenhalf, C.S. Foster, J.P. Neoptolemos Detailed tissue expression of bcl-2, bax, bak and bcl-x in the normal human pancreas and in chronic pancreatitis, ampullary and pancreatic ductal adenocarcinomas Pancreatology 1 2001 254 262
-
(2001)
Pancreatology
, vol.1
, pp. 254-262
-
-
Evans, J.D.1
Cornford, P.A.2
Dodson, A.3
Greenhalf, W.4
Foster, C.S.5
Neoptolemos, J.P.6
-
92
-
-
0033082995
-
IAP family proteins--suppressors of apoptosis
-
Q.L. Deveraux, J.C. Reed IAP family proteins--suppressors of apoptosis Genes Dev 13 1999 239 252
-
(1999)
Genes Dev
, vol.13
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
93
-
-
0035878930
-
Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumors
-
K. Satoh, K. Kaneko, M. Hirota, A. Masamune, A. Satoh, T. Shimosegawa Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumors Cancer 92 2001 271 278
-
(2001)
Cancer
, vol.92
, pp. 271-278
-
-
Satoh, K.1
Kaneko, K.2
Hirota, M.3
Masamune, A.4
Satoh, A.5
Shimosegawa, T.6
-
94
-
-
0037128687
-
Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma
-
A.I. Sarela, C.S. Verbeke, J. Ramsdale, C.L. Davies, A.F. Markham, P.J. Guillou Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma Br J Cancer 86 2002 886 892
-
(2002)
Br J Cancer
, vol.86
, pp. 886-892
-
-
Sarela, A.I.1
Verbeke, C.S.2
Ramsdale, J.3
Davies, C.L.4
Markham, A.F.5
Guillou, P.J.6
-
95
-
-
0036546501
-
NF-kappaB in cancer: From innocent bystander to major culprit
-
M. Karin, Y. Cao, F.R. Greten, Z.W. Li NF-kappaB in cancer from innocent bystander to major culprit Nat Rev Cancer 2 2002 301 310
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 301-310
-
-
Karin, M.1
Cao, Y.2
Greten, F.R.3
Li, Z.W.4
-
96
-
-
0032943591
-
The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells
-
W. Wang, J.L. Abbruzzese, D.B. Evans, L. Larry, K.R. Cleary, P.J. Chiao The nuclear factor-kappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells Clin Cancer Res 5 1999 119 127
-
(1999)
Clin Cancer Res
, vol.5
, pp. 119-127
-
-
Wang, W.1
Abbruzzese, J.L.2
Evans, D.B.3
Larry, L.4
Cleary, K.R.5
Chiao, P.J.6
-
97
-
-
0037780982
-
Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer
-
S. Liptay, C.K. Weber, L. Ludwig, M. Wagner, G. Adler, R.M. Schmid Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer Int J Cancer 105 2003 735 746
-
(2003)
Int J Cancer
, vol.105
, pp. 735-746
-
-
Liptay, S.1
Weber, C.K.2
Ludwig, L.3
Wagner, M.4
Adler, G.5
Schmid, R.M.6
-
98
-
-
0035864344
-
Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin
-
A. Arlt, J. Vorndamm, M. Breitenbroich, U.R. Folsch, H. Kalthoff, W.E. Schmidt, H. Schafer Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin Oncogene 20 2001 859 868
-
(2001)
Oncogene
, vol.20
, pp. 859-868
-
-
Arlt, A.1
Vorndamm, J.2
Breitenbroich, M.3
Folsch, U.R.4
Kalthoff, H.5
Schmidt, W.E.6
Schafer, H.7
-
99
-
-
0036672868
-
Selective targeting of the nuclear factor-kappaB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death
-
R.P. Thomas, B.J. Farrow, S. Kim, M.J. May, M.R. Hellmich, B.M. Evers Selective targeting of the nuclear factor-kappaB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death Surgery 132 2002 127 134
-
(2002)
Surgery
, vol.132
, pp. 127-134
-
-
Thomas, R.P.1
Farrow, B.J.2
Kim, S.3
May, M.J.4
Hellmich, M.R.5
Evers, B.M.6
-
100
-
-
0037457422
-
Usage of the NF-kappaB inhibitor sulfasalazine as sensitizing agent in combined chemotherapy of pancreatic cancer
-
S. Muerkoster, A. Arlt, M. Witt, A. Gehrz, S. Haye, C. March, F. Grohmann, K. Wegehenkel, H. Kalthoff, U.R. Folsch, H. Schafer Usage of the NF-kappaB inhibitor sulfasalazine as sensitizing agent in combined chemotherapy of pancreatic cancer Int J Cancer 104 2003 469 476
-
(2003)
Int J Cancer
, vol.104
, pp. 469-476
-
-
Muerkoster, S.1
Arlt, A.2
Witt, M.3
Gehrz, A.4
Haye, S.5
March, C.6
Grohmann, F.7
Wegehenkel, K.8
Kalthoff, H.9
Folsch, U.R.10
Schafer, H.11
-
101
-
-
0037743875
-
Chemosensitivity of human pancreatic carcinoma cells is enhanced by IkappaBalpha super-repressor
-
T. Sato, H. Odagiri, S.K. Ikenaga, M. Maruyama, M. Sasaki Chemosensitivity of human pancreatic carcinoma cells is enhanced by IkappaBalpha super-repressor Cancer Sci 94 2003 467 472
-
(2003)
Cancer Sci
, vol.94
, pp. 467-472
-
-
Sato, T.1
Odagiri, H.2
Ikenaga, S.K.3
Maruyama, M.4
Sasaki, M.5
-
102
-
-
0037422205
-
Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis
-
S. Fujioka, G.M. Sclabas, C. Schmidt, J. Niu, W.A. Frederick, Q.G. Dong, J.L. Abbruzzese, D.B. Evans, C. Baker, P.J. Chiao Inhibition of constitutive NF-kappa B activity by I kappa B alpha M suppresses tumorigenesis Oncogene 22 2003 1365 1370
-
(2003)
Oncogene
, vol.22
, pp. 1365-1370
-
-
Fujioka, S.1
Sclabas, G.M.2
Schmidt, C.3
Niu, J.4
Frederick, W.A.5
Dong, Q.G.6
Abbruzzese, J.L.7
Evans, D.B.8
Baker, C.9
Chiao, P.J.10
-
103
-
-
0037242595
-
Function of nuclear factor kappaB in pancreatic cancer metastasis
-
S. Fujioka, G.M. Sclabas, C. Schmidt, W.A. Frederick, Q.G. Dong, J.L. Abbruzzese, D.B. Evans, C. Baker, P.J. Chiao Function of nuclear factor kappaB in pancreatic cancer metastasis Clin Cancer Res 9 2003 346 354
-
(2003)
Clin Cancer Res
, vol.9
, pp. 346-354
-
-
Fujioka, S.1
Sclabas, G.M.2
Schmidt, C.3
Frederick, W.A.4
Dong, Q.G.5
Abbruzzese, J.L.6
Evans, D.B.7
Baker, C.8
Chiao, P.J.9
-
104
-
-
1542353401
-
Control of apoptosis by p53
-
J.S. Fridman, S.W. Lowe Control of apoptosis by p53 Oncogene 22 2003 9030 9040
-
(2003)
Oncogene
, vol.22
, pp. 9030-9040
-
-
Fridman, J.S.1
Lowe, S.W.2
-
105
-
-
0034977277
-
Apaf-1 is a transcriptional target for E2F and p53
-
M.C. Moroni, E.S. Hickman, E.L. Denchi, G. Caprara, E. Colli, F. Cecconi, H. Muller, K. Helin Apaf-1 is a transcriptional target for E2F and p53 Nat Cell Biol 3 2001 552 558
-
(2001)
Nat Cell Biol
, vol.3
, pp. 552-558
-
-
Moroni, M.C.1
Hickman, E.S.2
Denchi, E.L.3
Caprara, G.4
Colli, E.5
Cecconi, F.6
Muller, H.7
Helin, K.8
-
106
-
-
85006277004
-
Direct coupling of the cell cycle and cell death machinery by E2F
-
Z. Nahle, J. Polakoff, R.V. Davuluri, M.E. McCurrach, M.D. Jacobson, M. Narita, M.Q. Zhang, Y. Lazebnik, D. Bar-Sagi, S.W. Lowe Direct coupling of the cell cycle and cell death machinery by E2F Nat Cell Biol 4 2002 859 864
-
(2002)
Nat Cell Biol
, vol.4
, pp. 859-864
-
-
Nahle, Z.1
Polakoff, J.2
Davuluri, R.V.3
McCurrach, M.E.4
Jacobson, M.D.5
Narita, M.6
Zhang, M.Q.7
Lazebnik, Y.8
Bar-Sagi, D.9
Lowe, S.W.10
-
107
-
-
1542305653
-
Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis
-
T. Hershko, D. Ginsberg Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis J Biol Chem 279 2004 8627 8634
-
(2004)
J Biol Chem
, vol.279
, pp. 8627-8634
-
-
Hershko, T.1
Ginsberg, D.2
-
108
-
-
0036275624
-
E2F-1 gene therapy induces apoptosis and increases chemosensitivity in human pancreatic carcinoma cells
-
M.J. Elliott, M.R. Farmer, C. Atienza Jr, A. Stilwell, Y.B. Dong, H.L. Yang, S.L. Wong, K.M. McMasters E2F-1 gene therapy induces apoptosis and increases chemosensitivity in human pancreatic carcinoma cells Tumour Biol 23 2002 76 86
-
(2002)
Tumour Biol
, vol.23
, pp. 76-86
-
-
Elliott, M.J.1
Farmer, M.R.2
Atienza Jr., C.3
Stilwell, A.4
Dong, Y.B.5
Yang, H.L.6
Wong, S.L.7
McMasters, K.M.8
-
109
-
-
0037116623
-
Overexpression of pRB in human pancreatic carcinoma cells: Function in chemotherapy-induced apoptosis
-
T. Plath, M. Peters, K. Detjen, M. Welzel, Z. von Marschall, C. Radke, B. Wiedenmann, S. Rosewicz Overexpression of pRB in human pancreatic carcinoma cells function in chemotherapy-induced apoptosis J Natl Cancer Inst 94 2002 129 142
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 129-142
-
-
Plath, T.1
Peters, M.2
Detjen, K.3
Welzel, M.4
Von Marschall, Z.5
Radke, C.6
Wiedenmann, B.7
Rosewicz, S.8
-
110
-
-
3543092021
-
Pathways of apoptotic and non-apoptotic death in tumour cells
-
H. Okada, T.W. Mak Pathways of apoptotic and non-apoptotic death in tumour cells Nat Rev Cancer 4 2004 592 603
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 592-603
-
-
Okada, H.1
Mak, T.W.2
-
111
-
-
0023247255
-
Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice
-
D.M. Ornitz, R.E. Hammer, A. Messing, R.D. Palmiter, R.L. Brinster Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice Science 238 1987 188 193
-
(1987)
Science
, vol.238
, pp. 188-193
-
-
Ornitz, D.M.1
Hammer, R.E.2
Messing, A.3
Palmiter, R.D.4
Brinster, R.L.5
-
112
-
-
0023666146
-
Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice
-
C.J. Quaife, C.A. Pinkert, D.M. Ornitz, R.D. Palmiter, R.L. Brinster Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice Cell 48 1987 1023 1034
-
(1987)
Cell
, vol.48
, pp. 1023-1034
-
-
Quaife, C.J.1
Pinkert, C.A.2
Ornitz, D.M.3
Palmiter, R.D.4
Brinster, R.L.5
-
113
-
-
0025297086
-
Overexpression of TGF alpha in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
-
E.P. Sandgren, N.C. Luetteke, R.D. Palmiter, R.L. Brinster, D.C. Lee Overexpression of TGF alpha in transgenic mice induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast Cell 61 1990 1121 1135
-
(1990)
Cell
, vol.61
, pp. 1121-1135
-
-
Sandgren, E.P.1
Luetteke, N.C.2
Palmiter, R.D.3
Brinster, R.L.4
Lee, D.C.5
-
114
-
-
0026056967
-
Pancreatic tumor pathogenesis reflects the causative genetic lesion
-
E.P. Sandgren, C.J. Quaife, A.G. Paulovich, R.D. Palmiter, R.L. Brinster Pancreatic tumor pathogenesis reflects the causative genetic lesion Proc Natl Acad Sci U S A 88 1991 93 97
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 93-97
-
-
Sandgren, E.P.1
Quaife, C.J.2
Paulovich, A.G.3
Palmiter, R.D.4
Brinster, R.L.5
-
115
-
-
0031787342
-
Malignant transformation of duct-like cells originating from acini in transforming growth factor transgenic mice
-
M. Wagner, H. Luhrs, G. Kloppel, G. Adler, R.M. Schmid Malignant transformation of duct-like cells originating from acini in transforming growth factor transgenic mice Gastroenterology 115 1998 1254 1262
-
(1998)
Gastroenterology
, vol.115
, pp. 1254-1262
-
-
Wagner, M.1
Luhrs, H.2
Kloppel, G.3
Adler, G.4
Schmid, R.M.5
-
116
-
-
0035252589
-
A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease
-
M. Wagner, F.R. Greten, C.K. Weber, S. Koschnick, T. Mattfeldt, W. Deppert, H. Kern, G. Adler, R.M. Schmid A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease Genes Dev 15 2001 286 293
-
(2001)
Genes Dev
, vol.15
, pp. 286-293
-
-
Wagner, M.1
Greten, F.R.2
Weber, C.K.3
Koschnick, S.4
Mattfeldt, T.5
Deppert, W.6
Kern, H.7
Adler, G.8
Schmid, R.M.9
-
117
-
-
0036134968
-
Obligate roles for p16(Ink4a) and p19(Arf)-p53 in the suppression of murine pancreatic neoplasia
-
N. Bardeesy, J. Morgan, M. Sinha, S. Signoretti, S. Srivastava, M. Loda, G. Merlino, R.A. DePinho Obligate roles for p16(Ink4a) and p19(Arf)-p53 in the suppression of murine pancreatic neoplasia Mol Cell Biol 22 2002 635 643
-
(2002)
Mol Cell Biol
, vol.22
, pp. 635-643
-
-
Bardeesy, N.1
Morgan, J.2
Sinha, M.3
Signoretti, S.4
Srivastava, S.5
Loda, M.6
Merlino, G.7
DePinho, R.A.8
-
118
-
-
0038743167
-
The mutant K-ras oncogene causes pancreatic periductal lymphocytic infiltration and gastric mucous neck cell hyperplasia in transgenic mice
-
F.H. Brembeck, F.S. Schreiber, T.B. Deramaudt, L. Craig, B. Rhoades, G. Swain, P. Grippo, D.A. Stoffers, D.G. Silberg, A.K. Rustgi The mutant K-ras oncogene causes pancreatic periductal lymphocytic infiltration and gastric mucous neck cell hyperplasia in transgenic mice Cancer Res 63 2003 2005 2009
-
(2003)
Cancer Res
, vol.63
, pp. 2005-2009
-
-
Brembeck, F.H.1
Schreiber, F.S.2
Deramaudt, T.B.3
Craig, L.4
Rhoades, B.5
Swain, G.6
Grippo, P.7
Stoffers, D.A.8
Silberg, D.G.9
Rustgi, A.K.10
-
119
-
-
0038405066
-
Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant Kras in transgenic mice
-
P.J. Grippo, P.S. Nowlin, M.J. Demeure, D.S. Longnecker, E.P. Sandgren Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant Kras in transgenic mice Cancer Res 63 2003 2016 2019
-
(2003)
Cancer Res
, vol.63
, pp. 2016-2019
-
-
Grippo, P.J.1
Nowlin, P.S.2
Demeure, M.J.3
Longnecker, D.S.4
Sandgren, E.P.5
-
120
-
-
0345687862
-
Genes, signals, and lineages in pancreas development
-
L.C. Murtaugh, D.A. Melton Genes, signals, and lineages in pancreas development Annu Rev Cell Dev Biol 19 2003 71 89
-
(2003)
Annu Rev Cell Dev Biol
, vol.19
, pp. 71-89
-
-
Murtaugh, L.C.1
Melton, D.A.2
-
121
-
-
0036301577
-
Pancreatic organogenesis--developmental mechanisms and implications for therapy
-
H. Edlund Pancreatic organogenesis--developmental mechanisms and implications for therapy Nat Rev Genet 3 2002 524 532
-
(2002)
Nat Rev Genet
, vol.3
, pp. 524-532
-
-
Edlund, H.1
-
122
-
-
0035863135
-
Intercellular signals regulating pancreas development and function
-
S.K. Kim, M. Hebrok Intercellular signals regulating pancreas development and function Genes Dev 15 2001 111 127
-
(2001)
Genes Dev
, vol.15
, pp. 111-127
-
-
Kim, S.K.1
Hebrok, M.2
-
123
-
-
0029950724
-
The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice
-
U. Ahlgren, J. Jonsson, H. Edlund The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice Development 122 1996 1409 1416
-
(1996)
Development
, vol.122
, pp. 1409-1416
-
-
Ahlgren, U.1
Jonsson, J.2
Edlund, H.3
-
124
-
-
0029868156
-
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
-
M.F. Offield, T.L. Jetton, P.A. Labosky, M. Ray, R.W. Stein, M.A. Magnuson, B.L. Hogan, C.V. Wright PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum Development 122 1996 983 995
-
(1996)
Development
, vol.122
, pp. 983-995
-
-
Offield, M.F.1
Jetton, T.L.2
Labosky, P.A.3
Ray, M.4
Stein, R.W.5
Magnuson, M.A.6
Hogan, B.L.7
Wright, C.V.8
-
125
-
-
0037125977
-
Experimental control of pancreatic development and maintenance
-
A.M. Holland, M.A. Hale, H. Kagami, R.E. Hammer, R.J. MacDonald Experimental control of pancreatic development and maintenance Proc Natl Acad Sci U S A 99 2002 12236 12241
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12236-12241
-
-
Holland, A.M.1
Hale, M.A.2
Kagami, H.3
Hammer, R.E.4
MacDonald, R.J.5
-
126
-
-
0032734761
-
Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha
-
S.Y. Song, M. Gannon, M.K. Washington, C.R. Scoggins, I.M. Meszoely, J.R. Goldenring, C.R. Marino, E.P. Sandgren, R.J. Coffey Jr, C.V. Wright, S.D. Leach Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha Gastroenterology 117 1999 1416 1426
-
(1999)
Gastroenterology
, vol.117
, pp. 1416-1426
-
-
Song, S.Y.1
Gannon, M.2
Washington, M.K.3
Scoggins, C.R.4
Meszoely, I.M.5
Goldenring, J.R.6
Marino, C.R.7
Sandgren, E.P.8
Coffey Jr., R.J.9
Wright, C.V.10
Leach, S.D.11
-
127
-
-
0036730427
-
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
-
Y. Kawaguchi, B. Cooper, M. Gannon, M. Ray, R.J. MacDonald, C.V. Wright The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors Nat Genet 32 2002 128 134
-
(2002)
Nat Genet
, vol.32
, pp. 128-134
-
-
Kawaguchi, Y.1
Cooper, B.2
Gannon, M.3
Ray, M.4
MacDonald, R.J.5
Wright, C.V.6
-
128
-
-
16844367242
-
Aberrant localization of intracellular organelles, Ca2+ signaling and exocytosis in Mist1 null mice
-
X. Luo, D.M. Shin, X. Wang, S.F. Konieczny, S. Muallem Aberrant localization of intracellular organelles, Ca2+ signaling and exocytosis in Mist1 null mice J Biol Chem 280 2005 12668 12675
-
(2005)
J Biol Chem
, vol.280
, pp. 12668-12675
-
-
Luo, X.1
Shin, D.M.2
Wang, X.3
Konieczny, S.F.4
Muallem, S.5
-
129
-
-
1642335543
-
Inhibition of Mist1 homodimer formation induces pancreatic acinar-to-ductal metaplasia
-
L. Zhu, T. Tran, J.M. Rukstalis, P. Sun, B. Damsz, S.F. Konieczny Inhibition of Mist1 homodimer formation induces pancreatic acinar-to-ductal metaplasia Mol Cell Biol 24 2004 2673 2681
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2673-2681
-
-
Zhu, L.1
Tran, T.2
Rukstalis, J.M.3
Sun, P.4
Damsz, B.5
Konieczny, S.F.6
-
130
-
-
9144266295
-
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
-
S.R. Hingorani, E.F. Petricoin, A. Maitra, V. Rajapakse, C. King, M.A. Jacobetz, S. Ross, T.P. Conrads, T.D. Veenstra, B.A. Hitt, Y. Kawaguchi, D. Johann, L.A. Liotta, H.C. Crawford, M.E. Putt, T. Jacks, C.V. Wright, R.H. Hruban, A.M. Lowy, D.A. Tuveson Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse Cancer Cell 4 2003 437 450
-
(2003)
Cancer Cell
, vol.4
, pp. 437-450
-
-
Hingorani, S.R.1
Petricoin, E.F.2
Maitra, A.3
Rajapakse, V.4
King, C.5
Jacobetz, M.A.6
Ross, S.7
Conrads, T.P.8
Veenstra, T.D.9
Hitt, B.A.10
Kawaguchi, Y.11
Johann, D.12
Liotta, L.A.13
Crawford, H.C.14
Putt, M.E.15
Jacks, T.16
Wright, C.V.17
Hruban, R.H.18
Lowy, A.M.19
Tuveson, D.A.20
more..
-
131
-
-
0346455774
-
Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma
-
A.J. Aguirre, N. Bardeesy, M. Sinha, L. Lopez, D.A. Tuveson, J. Horner, M.S. Redston, R.A. DePinho Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma Genes Dev 17 2003 3112 3126
-
(2003)
Genes Dev
, vol.17
, pp. 3112-3126
-
-
Aguirre, A.J.1
Bardeesy, N.2
Sinha, M.3
Lopez, L.4
Tuveson, D.A.5
Horner, J.6
Redston, M.S.7
DePinho, R.A.8
-
132
-
-
10744223624
-
Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis
-
Y. Miyamoto, A. Maitra, B. Ghosh, U. Zechner, P. Argani, C.A. Iacobuzio-Donahue, V. Sriuranpong, T. Iso, I.M. Meszoely, M.S. Wolfe, R.H. Hruban, D.W. Ball, R.M. Schmid, S.D. Leach Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis Cancer Cell 3 2003 565 576
-
(2003)
Cancer Cell
, vol.3
, pp. 565-576
-
-
Miyamoto, Y.1
Maitra, A.2
Ghosh, B.3
Zechner, U.4
Argani, P.5
Iacobuzio-Donahue, C.A.6
Sriuranpong, V.7
Iso, T.8
Meszoely, I.M.9
Wolfe, M.S.10
Hruban, R.H.11
Ball, D.W.12
Schmid, R.M.13
Leach, S.D.14
-
133
-
-
5444256238
-
Self-renewal and solid tumor stem cells
-
M. Al-Hajj, M.F. Clarke Self-renewal and solid tumor stem cells Oncogene 23 2004 7274 7282
-
(2004)
Oncogene
, vol.23
, pp. 7274-7282
-
-
Al-Hajj, M.1
Clarke, M.F.2
-
134
-
-
0345059767
-
Applying the principles of stem-cell biology to cancer
-
R. Pardal, M.F. Clarke, S.J. Morrison Applying the principles of stem-cell biology to cancer Nat Rev Cancer 3 2003 895 902
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 895-902
-
-
Pardal, R.1
Clarke, M.F.2
Morrison, S.J.3
-
135
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
S.P. Thayer, M.P. di Magliano, P.W. Heiser, C.M. Nielsen, D.J. Roberts, G.Y. Lauwers, Y.P. Qi, S. Gysin, C. Fernandez-del Castillo, V. Yajnik, B. Antoniu, M. McMahon, A.L. Warshaw, M. Hebrok Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis Nature 425 2003 851 856
-
(2003)
Nature
, vol.425
, pp. 851-856
-
-
Thayer, S.P.1
Di Magliano, M.P.2
Heiser, P.W.3
Nielsen, C.M.4
Roberts, D.J.5
Lauwers, G.Y.6
Qi, Y.P.7
Gysin, S.8
Fernandez-del Castillo, C.9
Yajnik, V.10
Antoniu, B.11
McMahon, M.12
Warshaw, A.L.13
Hebrok, M.14
-
136
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
D.M. Berman, S.S. Karhadkar, A. Maitra, R. Montes De Oca, M.R. Gerstenblith, K. Briggs, A.R. Parker, Y. Shimada, J.R. Eshleman, D.N. Watkins, P.A. Beachy Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours Nature 425 2003 846 851
-
(2003)
Nature
, vol.425
, pp. 846-851
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
Montes De Oca, R.4
Gerstenblith, M.R.5
Briggs, K.6
Parker, A.R.7
Shimada, Y.8
Eshleman, J.R.9
Watkins, D.N.10
Beachy, P.A.11
-
137
-
-
0346731132
-
The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer
-
B.C. Lewis, D.S. Klimstra, H.E. Varmus The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer Genes Dev 17 2003 3127 3138
-
(2003)
Genes Dev
, vol.17
, pp. 3127-3138
-
-
Lewis, B.C.1
Klimstra, D.S.2
Varmus, H.E.3
-
138
-
-
0032985541
-
Pancreatic cancer: A report of treatment and survival trends for 100,313 patients diagnosed from 1985-1995, using the National Cancer Database
-
S.F. Sener, A. Fremgen, H.R. Menck, D.P. Winchester Pancreatic cancer a report of treatment and survival trends for 100,313 patients diagnosed from 1985-1995, using the National Cancer Database J Am Coll Surg 189 1999 1 7
-
(1999)
J Am Coll Surg
, vol.189
, pp. 1-7
-
-
Sener, S.F.1
Fremgen, A.2
Menck, H.R.3
Winchester, D.P.4
-
139
-
-
0038644769
-
Long-term results of partial pancreaticoduodenectomy for ductal adenocarcinoma of the pancreatic head: 25-Year experience
-
A. Richter, M. Niedergethmann, J.W. Sturm, D. Lorenz, S. Post, M. Trede Long-term results of partial pancreaticoduodenectomy for ductal adenocarcinoma of the pancreatic head 25-year experience World J Surg 27 2003 324 329
-
(2003)
World J Surg
, vol.27
, pp. 324-329
-
-
Richter, A.1
Niedergethmann, M.2
Sturm, J.W.3
Lorenz, D.4
Post, S.5
Trede, M.6
-
140
-
-
2442490662
-
Curative resection is the single most important factor determining outcome in patients with pancreatic adenocarcinoma
-
M. Wagner, C. Redaelli, M. Lietz, C.A. Seiler, H. Friess, M.W. Buchler Curative resection is the single most important factor determining outcome in patients with pancreatic adenocarcinoma Br J Surg 91 2004 586 594
-
(2004)
Br J Surg
, vol.91
, pp. 586-594
-
-
Wagner, M.1
Redaelli, C.2
Lietz, M.3
Seiler, C.A.4
Friess, H.5
Buchler, M.W.6
-
141
-
-
0035212974
-
Influence of resection margins on survival for patients with pancreatic cancer treated by adjuvant chemoradiation and/or chemotherapy in the ESPAC-1 randomized controlled trial
-
J.P. Neoptolemos, D.D. Stocken, J.A. Dunn, J. Almond, H.G. Beger, P. Pederzoli, C. Bassi, C. Dervenis, L. Fernandez-Cruz, F. Lacaine, J. Buckels, M. Deakin, F.A. Adab, R. Sutton, C. Imrie, I. Ihse, T. Tihanyi, A. Olah, S. Pedrazzoli, D. Spooner, D.J. Kerr, H. Friess, M.W. Buchler Influence of resection margins on survival for patients with pancreatic cancer treated by adjuvant chemoradiation and/or chemotherapy in the ESPAC-1 randomized controlled trial Ann Surg 234 2001 758 768
-
(2001)
Ann Surg
, vol.234
, pp. 758-768
-
-
Neoptolemos, J.P.1
Stocken, D.D.2
Dunn, J.A.3
Almond, J.4
Beger, H.G.5
Pederzoli, P.6
Bassi, C.7
Dervenis, C.8
Fernandez-Cruz, L.9
Lacaine, F.10
Buckels, J.11
Deakin, M.12
Adab, F.A.13
Sutton, R.14
Imrie, C.15
Ihse, I.16
Tihanyi, T.17
Olah, A.18
Pedrazzoli, S.19
Spooner, D.20
Kerr, D.J.21
Friess, H.22
Buchler, M.W.23
more..
-
142
-
-
12144287320
-
A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer
-
J.P. Neoptolemos, D.D. Stocken, H. Friess, C. Bassi, J.A. Dunn, H. Hickey, H. Beger, L. Fernandez-Cruz, C. Dervenis, F. Lacaine, M. Falconi, P. Pederzoli, A. Pap, D. Spooner, D.J. Kerr, M.W. Buchler A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer N Engl J Med 350 2004 1200 1210
-
(2004)
N Engl J Med
, vol.350
, pp. 1200-1210
-
-
Neoptolemos, J.P.1
Stocken, D.D.2
Friess, H.3
Bassi, C.4
Dunn, J.A.5
Hickey, H.6
Beger, H.7
Fernandez-Cruz, L.8
Dervenis, C.9
Lacaine, F.10
Falconi, M.11
Pederzoli, P.12
Pap, A.13
Spooner, D.14
Kerr, D.J.15
Buchler, M.W.16
-
143
-
-
0037406666
-
Interferon-based adjuvant chemoradiation therapy after pancreaticoduodenectomy for pancreatic adenocarcinoma
-
V.J. Picozzi, R.A. Kozarek, L.W. Traverso Interferon-based adjuvant chemoradiation therapy after pancreaticoduodenectomy for pancreatic adenocarcinoma Am J Surg 185 2003 476 480
-
(2003)
Am J Surg
, vol.185
, pp. 476-480
-
-
Picozzi, V.J.1
Kozarek, R.A.2
Traverso, L.W.3
-
144
-
-
0031972708
-
Phase II trial of preoperative radiation therapy and chemotherapy for patients with localized, resectable adenocarcinoma of the pancreas: An Eastern Cooperative Oncology Group Study
-
J.P. Hoffman, S. Lipsitz, T. Pisansky, J.L. Weese, L. Solin, A.B. Benson III Phase II trial of preoperative radiation therapy and chemotherapy for patients with localized, resectable adenocarcinoma of the pancreas an Eastern Cooperative Oncology Group Study J Clin Oncol 16 1998 317 323
-
(1998)
J Clin Oncol
, vol.16
, pp. 317-323
-
-
Hoffman, J.P.1
Lipsitz, S.2
Pisansky, T.3
Weese, J.L.4
Solin, L.5
Benson III, A.B.6
-
145
-
-
4444325559
-
Neoadjuvant therapy for resectable pancreatic cancer
-
C.P. Raut, D.B. Evans, C.H. Crane, P.W. Pisters, R.A. Wolff Neoadjuvant therapy for resectable pancreatic cancer Surg Oncol Clin North Am 13 2004 639 661 ix
-
(2004)
Surg Oncol Clin North Am
, vol.13
, pp. 639-661
-
-
Raut, C.P.1
Evans, D.B.2
Crane, C.H.3
Pisters, P.W.4
Wolff, R.A.5
-
146
-
-
0023722682
-
Treatment of locally unresectable carcinoma of the pancreas. Comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone
-
Gastrointestinal Tumor Study Group
-
Gastrointestinal Tumor Study Group Treatment of locally unresectable carcinoma of the pancreas. comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone J Natl Cancer Inst 80 1988 751 755
-
(1988)
J Natl Cancer Inst
, vol.80
, pp. 751-755
-
-
-
147
-
-
0021918519
-
Treatment of locally unresectable cancer of the stomach and pancreas: A randomized comparison of 5-fluorouracil alone with radiation plus concurrent and maintenance 5-fluorouracil--an Eastern Cooperative Oncology Group study
-
D.J. Klaassen, J.M. MacIntyre, G.E. Catton, P.F. Engstrom, C.G. Moertel Treatment of locally unresectable cancer of the stomach and pancreas a randomized comparison of 5-fluorouracil alone with radiation plus concurrent and maintenance 5-fluorouracil--an Eastern Cooperative Oncology Group study J Clin Oncol 3 1985 373 378
-
(1985)
J Clin Oncol
, vol.3
, pp. 373-378
-
-
Klaassen, D.J.1
MacIntyre, J.M.2
Catton, G.E.3
Engstrom, P.F.4
Moertel, C.G.5
-
148
-
-
0019811740
-
Multi-drug chemotherapy with and without radiation for carcinoma of the stomach and pancreas: A prospective randomized trial
-
J.J. Hazel, M.P. Thirlwell, M. Huggins, A. Maksymiuk, J.K. MacFarlane Multi-drug chemotherapy with and without radiation for carcinoma of the stomach and pancreas a prospective randomized trial J Can Assoc Radiol 32 1981 164 165
-
(1981)
J Can Assoc Radiol
, vol.32
, pp. 164-165
-
-
Hazel, J.J.1
Thirlwell, M.P.2
Huggins, M.3
Maksymiuk, A.4
MacFarlane, J.K.5
-
149
-
-
0035034896
-
Radiologic diagnosis and staging of pancreatic ductal adenocarcinoma
-
N.C. Balci, R.C. Semelka Radiologic diagnosis and staging of pancreatic ductal adenocarcinoma Eur J Radiol 38 2001 105 112
-
(2001)
Eur J Radiol
, vol.38
, pp. 105-112
-
-
Balci, N.C.1
Semelka, R.C.2
-
151
-
-
84944367593
-
A comparison of three chemotherapeutic regimens in the treatment of advanced pancreatic and gastric carcinoma. Fluorouracil vs fluorouracil and doxorubicin vs fluorouracil, doxorubicin, and mitomycin
-
S.A. Cullinan, C.G. Moertel, T.R. Fleming, J.R. Rubin, J.E. Krook, L.K. Everson, H.E. Windschitl, D.I. Twito, R.F. Marschke, J.F. Foley A comparison of three chemotherapeutic regimens in the treatment of advanced pancreatic and gastric carcinoma. Fluorouracil vs fluorouracil and doxorubicin vs fluorouracil, doxorubicin, and mitomycin JAMA 253 1985 2061 2067
-
(1985)
JAMA
, vol.253
, pp. 2061-2067
-
-
Cullinan, S.A.1
Moertel, C.G.2
Fleming, T.R.3
Rubin, J.R.4
Krook, J.E.5
Everson, L.K.6
Windschitl, H.E.7
Twito, D.I.8
Marschke, R.F.9
Foley, J.F.10
-
152
-
-
0030049697
-
Phase II study of gemcitabine in patients with advanced pancreatic cancer
-
J. Carmichael, U. Fink, R.C. Russell, M.F. Spittle, A.L. Harris, G. Spiessi, J. Blatter Phase II study of gemcitabine in patients with advanced pancreatic cancer Br J Cancer 73 1996 101 105
-
(1996)
Br J Cancer
, vol.73
, pp. 101-105
-
-
Carmichael, J.1
Fink, U.2
Russell, R.C.3
Spittle, M.F.4
Harris, A.L.5
Spiessi, G.6
Blatter, J.7
-
153
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
-
H.A. Burris III, M.J. Moore, J. Andersen, M.R. Green, M.L. Rothenberg, M.R. Modiano, M.C. Cripps, R.K. Portenoy, A.M. Storniolo, P. Tarassoff, R. Nelson, F.A. Dorr, C.D. Stephens, D.D. Von Hoff Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer a randomized trial J Clin Oncol 15 1997 2403 2413
-
(1997)
J Clin Oncol
, vol.15
, pp. 2403-2413
-
-
Burris III, H.A.1
Moore, M.J.2
Andersen, J.3
Green, M.R.4
Rothenberg, M.L.5
Modiano, M.R.6
Cripps, M.C.7
Portenoy, R.K.8
Storniolo, A.M.9
Tarassoff, P.10
Nelson, R.11
Dorr, F.A.12
Stephens, C.D.13
Von Hoff, D.D.14
-
154
-
-
0025987989
-
A phase III comparison trial of streptozotocin, mitomycin, and 5-fluorouracil with cisplatin, cytosine arabinoside, and caffeine in patients with advanced pancreatic carcinoma
-
D. Kelsen, C. Hudis, D. Niedzwiecki, J. Dougherty, E. Casper, J. Botet, V. Vinciguerra, R. Rosenbluth A phase III comparison trial of streptozotocin, mitomycin, and 5-fluorouracil with cisplatin, cytosine arabinoside, and caffeine in patients with advanced pancreatic carcinoma Cancer 68 1991 965 969
-
(1991)
Cancer
, vol.68
, pp. 965-969
-
-
Kelsen, D.1
Hudis, C.2
Niedzwiecki, D.3
Dougherty, J.4
Casper, E.5
Botet, J.6
Vinciguerra, V.7
Rosenbluth, R.8
-
155
-
-
0037099604
-
Multicenter randomized phase III trial comparing protracted venous infusion (PVI) fluorouracil (5-FU) with PVI 5-FU plus mitomycin in inoperable pancreatic cancer
-
N. Maisey, I. Chau, D. Cunningham, A. Norman, M. Seymour, T. Hickish, T. Iveson, M. O'Brien, N. Tebbutt, A. Harrington, M. Hill Multicenter randomized phase III trial comparing protracted venous infusion (PVI) fluorouracil (5-FU) with PVI 5-FU plus mitomycin in inoperable pancreatic cancer J Clin Oncol 20 2002 3130 3136
-
(2002)
J Clin Oncol
, vol.20
, pp. 3130-3136
-
-
Maisey, N.1
Chau, I.2
Cunningham, D.3
Norman, A.4
Seymour, M.5
Hickish, T.6
Iveson, T.7
O'Brien, M.8
Tebbutt, N.9
Harrington, A.10
Hill, M.11
-
156
-
-
0034815137
-
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of gemcitabine for the treatment of pancreatic cancer
-
S. Ward, E. Morris, N. Bansback, N. Calvert, A. Crellin, D. Forman, M. Larvin, D. Radstone A rapid and systematic review of the clinical effectiveness and cost-effectiveness of gemcitabine for the treatment of pancreatic cancer Health Technol Assess 5 2001 1 70
-
(2001)
Health Technol Assess
, vol.5
, pp. 1-70
-
-
Ward, S.1
Morris, E.2
Bansback, N.3
Calvert, N.4
Crellin, A.5
Forman, D.6
Larvin, M.7
Radstone, D.8
-
157
-
-
0036682041
-
Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297
-
J.D. Berlin, P. Catalano, J.P. Thomas, J.W. Kugler, D.G. Haller, A.B. Benson III Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma Eastern Cooperative Oncology Group Trial E2297 J Clin Oncol 20 2002 3270 3275
-
(2002)
J Clin Oncol
, vol.20
, pp. 3270-3275
-
-
Berlin, J.D.1
Catalano, P.2
Thomas, J.P.3
Kugler, J.W.4
Haller, D.G.5
Benson III, A.B.6
-
158
-
-
0037208590
-
Combining capecitabine and gemcitabine in patients with advanced pancreatic carcinoma: A phase I/II trial
-
V. Hess, M. Salzberg, M. Borner, R. Morant, A.D. Roth, C. Ludwig, R. Herrmann Combining capecitabine and gemcitabine in patients with advanced pancreatic carcinoma a phase I/II trial J Clin Oncol 21 2003 66 68
-
(2003)
J Clin Oncol
, vol.21
, pp. 66-68
-
-
Hess, V.1
Salzberg, M.2
Borner, M.3
Morant, R.4
Roth, A.D.5
Ludwig, C.6
Herrmann, R.7
-
159
-
-
0032902066
-
Phase II study of docetaxel in patients with metastatic pancreatic cancer: A Japanese cooperative study
-
Cooperative Group of Docetaxel for Pancreatic Cancer in Japan T.
-
S. Okada, Y. Sakata, S. Matsuno, M. Kurihara, Y. Sasaki, Y. Ohashi, T. Taguchi Cooperative Group of Docetaxel for Pancreatic Cancer in Japan Phase II study of docetaxel in patients with metastatic pancreatic cancer a Japanese cooperative study Br J Cancer 80 1999 438 443
-
(1999)
Br J Cancer
, vol.80
, pp. 438-443
-
-
Okada, S.1
Sakata, Y.2
Matsuno, S.3
Kurihara, M.4
Sasaki, Y.5
Ohashi, Y.6
Taguchi7
-
160
-
-
0036294677
-
Phase II study of docetaxel in patients with pancreatic cancer previously untreated with cytotoxic chemotherapy
-
R. Lenzi, S. Yalcin, D.B. Evans, J.L. Abbruzzese Phase II study of docetaxel in patients with pancreatic cancer previously untreated with cytotoxic chemotherapy Cancer Invest 20 2002 464 472
-
(2002)
Cancer Invest
, vol.20
, pp. 464-472
-
-
Lenzi, R.1
Yalcin, S.2
Evans, D.B.3
Abbruzzese, J.L.4
-
161
-
-
0033002404
-
Treatment of pancreatic cancer with docetaxel and granulocyte colony-stimulating factor: A multicenter phase II study
-
N. Androulakis, C. Kourousis, M.A. Dimopoulos, G. Samelis, S. Kakolyris, N. Tsavaris, K. Genatas, G. Aravantinos, C. Papadimitriou, S. Karabekios, G.P. Stathopoulos, V. Georgoulias Treatment of pancreatic cancer with docetaxel and granulocyte colony-stimulating factor a multicenter phase II study J Clin Oncol 17 1999 1779 1785
-
(1999)
J Clin Oncol
, vol.17
, pp. 1779-1785
-
-
Androulakis, N.1
Kourousis, C.2
Dimopoulos, M.A.3
Samelis, G.4
Kakolyris, S.5
Tsavaris, N.6
Genatas, K.7
Aravantinos, G.8
Papadimitriou, C.9
Karabekios, S.10
Stathopoulos, G.P.11
Georgoulias, V.12
-
162
-
-
0034122470
-
A phase II study: Docetaxel as first-line chemotherapy for advanced pancreatic adenocarcinoma
-
P. Rougier, A. Adenis, M. Ducreux, M. de Forni, J. Bonneterre, M. Dembak, P. Clouet, A. Lebecq, P. Baille, F. Lefresne-Soulas, C. Blanc, J.P. Armand A phase II study docetaxel as first-line chemotherapy for advanced pancreatic adenocarcinoma Eur J Cancer 36 2000 1016 1025
-
(2000)
Eur J Cancer
, vol.36
, pp. 1016-1025
-
-
Rougier, P.1
Adenis, A.2
Ducreux, M.3
De Forni, M.4
Bonneterre, J.5
Dembak, M.6
Clouet, P.7
Lebecq, A.8
Baille, P.9
Lefresne-Soulas, F.10
Blanc, C.11
Armand, J.P.12
-
163
-
-
0031662273
-
Tau expression in model adenocarcinomas correlates with docetaxel sensitivity in tumour-bearing mice
-
R. Veitia, M.C. Bissery, C. Martinez, A. Fellous Tau expression in model adenocarcinomas correlates with docetaxel sensitivity in tumour-bearing mice Br J Cancer 78 1998 871 877
-
(1998)
Br J Cancer
, vol.78
, pp. 871-877
-
-
Veitia, R.1
Bissery, M.C.2
Martinez, C.3
Fellous, A.4
-
164
-
-
4544269347
-
The evolution of adjuvant and neoadjuvant chemotherapy and radiation for advanced pancreatic cancer: From 5-fluorouracil to GTX
-
D.R. Fogelman, J. Chen, J.A. Chabot, J.D. Allendorf, B.A. Schrope, R.D. Ennis, S.M. Schreibman, R.L. Fine The evolution of adjuvant and neoadjuvant chemotherapy and radiation for advanced pancreatic cancer from 5-fluorouracil to GTX Surg Oncol Clin North Am 13 2004 711 735 x
-
(2004)
Surg Oncol Clin North Am
, vol.13
, pp. 711-735
-
-
Fogelman, D.R.1
Chen, J.2
Chabot, J.A.3
Allendorf, J.D.4
Schrope, B.A.5
Ennis, R.D.6
Schreibman, S.M.7
Fine, R.L.8
-
165
-
-
4644327989
-
Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate
-
C.M. Rocha Lima, M.R. Green, R. Rotche, W.H. Miller Jr, G.M. Jeffrey, L.A. Cisar, A. Morganti, N. Orlando, G. Gruia, L.L. Miller Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate J Clin Oncol 22 2004 3776 3783
-
(2004)
J Clin Oncol
, vol.22
, pp. 3776-3783
-
-
Rocha Lima, C.M.1
Green, M.R.2
Rotche, R.3
Miller Jr., W.H.4
Jeffrey, G.M.5
Cisar, L.A.6
Morganti, A.7
Orlando, N.8
Gruia, G.9
Miller, L.L.10
-
166
-
-
16444384413
-
A randomized phase III trial of DX-8951f (exatecan mesylate; DX) and gemcitabine (GEM) vs. gemcitabine alone in advanced pancreatic cancer (APC)
-
E.M. O'Reilly, G.K. Abou-Alfa, R. Letourneau, W.G. Harker, M. Modiano, H. Hurwitz, N.S. Tchekmedyian, J. Ackerman, R.L. De Jager, S.G. Eckardt A randomized phase III trial of DX-8951f (exatecan mesylate; DX) and gemcitabine (GEM) vs. gemcitabine alone in advanced pancreatic cancer (APC) (abstr 4006) Proc Am Soc Clin Oncol 23 2004
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
-
-
O'Reilly, E.M.1
Abou-Alfa, G.K.2
Letourneau, R.3
Harker, W.G.4
Modiano, M.5
Hurwitz, H.6
Tchekmedyian, N.S.7
Ackerman, J.8
De Jager, R.L.9
Eckardt, S.G.10
-
167
-
-
18744367197
-
Phase III results of exatecan (DX-8951f) versus gemcitabine (Gem) in chemotherapy-naïve patients with advanced pancreatic cancer (APC)
-
P. Cheverton, H. Friess, C. Andras, T. Salek, C. Geddes, G. Bodoky, J. Valle, Y. Humblet Phase III results of exatecan (DX-8951f) versus gemcitabine (Gem) in chemotherapy-naïve patients with advanced pancreatic cancer (APC) (abstr 4005) Proc Am Soc Clin Oncol 23 2004
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
-
-
Cheverton, P.1
Friess, H.2
Andras, C.3
Salek, T.4
Geddes, C.5
Bodoky, G.6
Valle, J.7
Humblet, Y.8
-
168
-
-
0028889426
-
Schedule-dependent antitumor effect of gemcitabine in in vivo model system
-
B.J. Braakhuis, V.W. Ruiz van Haperen, E. Boven, G. Veerman, G.J. Peters Schedule-dependent antitumor effect of gemcitabine in in vivo model system Semin Oncol 22 1995 42 46
-
(1995)
Semin Oncol
, vol.22
, pp. 42-46
-
-
Braakhuis, B.J.1
Ruiz Van Haperen, V.W.2
Boven, E.3
Veerman, G.4
Peters, G.J.5
-
169
-
-
0142121290
-
Randomized phase II comparison of dose-intense gemcitabine: Thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma
-
M. Tempero, W. Plunkett, V. Ruiz Van Haperen, J. Hainsworth, H. Hochster, R. Lenzi, J. Abbruzzese Randomized phase II comparison of dose-intense gemcitabine thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma J Clin Oncol 21 2003 3402 3408
-
(2003)
J Clin Oncol
, vol.21
, pp. 3402-3408
-
-
Tempero, M.1
Plunkett, W.2
Ruiz Van Haperen, V.3
Hainsworth, J.4
Hochster, H.5
Lenzi, R.6
Abbruzzese, J.7
-
170
-
-
0037083621
-
Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma: A prospective, randomized phase III study of the Gruppo Oncologia dell'Italia Meridionale
-
G. Colucci, F. Giuliani, V. Gebbia, M. Biglietto, P. Rabitti, G. Uomo, S. Cigolari, A. Testa, E. Maiello, M. Lopez Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma a prospective, randomized phase III study of the Gruppo Oncologia dell'Italia Meridionale Cancer 94 2002 902 910
-
(2002)
Cancer
, vol.94
, pp. 902-910
-
-
Colucci, G.1
Giuliani, F.2
Gebbia, V.3
Biglietto, M.4
Rabitti, P.5
Uomo, G.6
Cigolari, S.7
Testa, A.8
Maiello, E.9
Lopez, M.10
-
171
-
-
1542358227
-
A phase III trial comparing gemcitabine plus cisplatin vs. gemcitabine alone in advanced pancreatic carcinoma
-
V. Heinemann, D. Quietzsch, F. Gieseler, M. Gonnermann, H. Schonekas, A. Rost, H. Neuhaus, C. Haag, C. Stoffregen, M. Clemens A phase III trial comparing gemcitabine plus cisplatin vs. gemcitabine alone in advanced pancreatic carcinoma (abstr 1003) Proc Am Soc Clin Oncol 22 2003
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
-
-
Heinemann, V.1
Quietzsch, D.2
Gieseler, F.3
Gonnermann, M.4
Schonekas, H.5
Rost, A.6
Neuhaus, H.7
Haag, C.8
Stoffregen, C.9
Clemens, M.10
-
172
-
-
16444383237
-
GemOx (gemcitabine + oxaliplatin) versus Gem (gemcitabine) in non resectable pancreatic adenocarcinoma: Final results of the GERCOR/GISCAD Intergroup phase III
-
C. Louvet, R. Labianca, P. Hammel, G. Lledo, Braud F. de, T. Andre, M. Cantore, M. Ducreux, A. Zaniboni, Gramont A. De GemOx (gemcitabine + oxaliplatin) versus Gem (gemcitabine) in non resectable pancreatic adenocarcinoma final results of the GERCOR/GISCAD Intergroup phase III (abstr 4008) Proc Am Soc Clin Oncol 23 2004
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
-
-
Louvet, C.1
Labianca, R.2
Hammel, P.3
Lledo, G.4
De Braud, F.5
Andre, T.6
Cantore, M.7
Ducreux, M.8
Zaniboni, A.9
De Gramont, A.10
-
173
-
-
0032423809
-
Epidermal growth factor and its receptor as prognostic indicators in Chinese patients with pancreatic cancer
-
M. Dong, Y. Nio, K.J. Guo, K. Tamura, Y.L. Tian, Y.T. Dong Epidermal growth factor and its receptor as prognostic indicators in Chinese patients with pancreatic cancer Anticancer Res 18 1998 4613 4619
-
(1998)
Anticancer Res
, vol.18
, pp. 4613-4619
-
-
Dong, M.1
Nio, Y.2
Guo, K.J.3
Tamura, K.4
Tian, Y.L.5
Dong, Y.T.6
-
174
-
-
4344590997
-
Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer: A multicenter phase II trial
-
H.Q. Xiong, A. Rosenberg, A. LoBuglio, W. Schmidt, R.A. Wolff, J. Deutsch, M. Needle, J.L. Abbruzzese Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor, in combination with gemcitabine for advanced pancreatic cancer a multicenter phase II trial J Clin Oncol 22 2004 2610 2616
-
(2004)
J Clin Oncol
, vol.22
, pp. 2610-2616
-
-
Xiong, H.Q.1
Rosenberg, A.2
LoBuglio, A.3
Schmidt, W.4
Wolff, R.A.5
Deutsch, J.6
Needle, M.7
Abbruzzese, J.L.8
-
175
-
-
33745651691
-
Erlotinib + gemcitabine in patients with unresectable pancreatic carcinoma: Results from a phase IB trial
-
B.W. Porterfield, T. Dragovich, A. Patnaik, E. Rowinsky, M. Huberman, T. Clinebell, M. Hamilton, A. Zitelli, P. Nadler, D. Wood Erlotinib + gemcitabine in patients with unresectable pancreatic carcinoma results from a phase IB trial (abstr 4110) Proc Am Soc Clin Oncol 23 2004 339
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
, pp. 339
-
-
Porterfield, B.W.1
Dragovich, T.2
Patnaik, A.3
Rowinsky, E.4
Huberman, M.5
Clinebell, T.6
Hamilton, M.7
Zitelli, A.8
Nadler, P.9
Wood, D.10
-
176
-
-
29044439943
-
Erlotinib improves survival when added to gemcitabine in patients with advanced pancreatic cancer. A phase III trial of the National Cancer Institute of Canada Clinical Trials Group [NCIC-CTG]
-
Hollywood, FL
-
Moore MJ, Goldstein D, Hamm J, Kotecha J, Gallinger S, Au HJ, Nomikos D, Ding K, Ptaszynski M, Parulekar W. Erlotinib improves survival when added to gemcitabine in patients with advanced pancreatic cancer. A phase III trial of the National Cancer Institute of Canada Clinical Trials Group [NCIC-CTG] (abstr 77). American Society of Clinical Oncology Gastrointestinal Cancers Symposium, Hollywood, FL, 2005.
-
(2005)
American Society of Clinical Oncology Gastrointestinal Cancers Symposium
-
-
Moore, M.J.1
Goldstein, D.2
Hamm, J.3
Kotecha, J.4
Gallinger, S.5
Au, H.J.6
Nomikos, D.7
Ding, K.8
Ptaszynski, M.9
Parulekar, W.10
-
177
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
H. Hurwitz, L. Fehrenbacher, W. Novotny, T. Cartwright, J. Hainsworth, W. Heim, J. Berlin, A. Baron, S. Griffing, E. Holmgren, N. Ferrara, G. Fyfe, B. Rogers, R. Ross, F. Kabbinavar Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer N Engl J Med 350 2004 2335 2342
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
178
-
-
8344258509
-
Bevacizumab (B) plus gemcitabine (G) in patient (pts) with advanced pancreatic cancer (PC): Updated results of a multi-center phase II trial
-
H.L. Kindler, G. Friberg, W.M. Stadler, D.A. Singh, G. Locker, S. Nattam, M. Kozloff, K. Kasza, E.E. Vokes Bevacizumab (B) plus gemcitabine (G) in patient (pts) with advanced pancreatic cancer (PC) updated results of a multi-center phase II trial (abstr 4009) Proc Am Soc Clin Oncol 23 2004 314
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
, pp. 314
-
-
Kindler, H.L.1
Friberg, G.2
Stadler, W.M.3
Singh, D.A.4
Locker, G.5
Nattam, S.6
Kozloff, M.7
Kasza, K.8
Vokes, E.E.9
-
179
-
-
1542615084
-
Celecoxib inhibits vascular endothelial growth factor expression in and reduces angiogenesis and metastasis of human pancreatic cancer via suppression of Sp1 transcription factor activity
-
D. Wei, L. Wang, Y. He, H.Q. Xiong, J.L. Abbruzzese, K. Xie Celecoxib inhibits vascular endothelial growth factor expression in and reduces angiogenesis and metastasis of human pancreatic cancer via suppression of Sp1 transcription factor activity Cancer Res 64 2004 2030 2038
-
(2004)
Cancer Res
, vol.64
, pp. 2030-2038
-
-
Wei, D.1
Wang, L.2
He, Y.3
Xiong, H.Q.4
Abbruzzese, J.L.5
Xie, K.6
-
180
-
-
0032519608
-
Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma
-
T. Koshiba, R. Hosotani, M. Wada, Y. Miyamoto, K. Fujimoto, J.U. Lee, R. Doi, S. Arii, M. Imamura Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma Cancer 82 1998 642 650
-
(1998)
Cancer
, vol.82
, pp. 642-650
-
-
Koshiba, T.1
Hosotani, R.2
Wada, M.3
Miyamoto, Y.4
Fujimoto, K.5
Lee, J.U.6
Doi, R.7
Arii, S.8
Imamura, M.9
-
181
-
-
0035424135
-
Marimastat as first-line therapy for patients with unresectable pancreatic cancer: A randomized trial
-
S.R. Bramhall, A. Rosemurgy, P.D. Brown, C. Bowry, J.A. Buckels Marimastat as first-line therapy for patients with unresectable pancreatic cancer a randomized trial J Clin Oncol 19 2001 3447 3455
-
(2001)
J Clin Oncol
, vol.19
, pp. 3447-3455
-
-
Bramhall, S.R.1
Rosemurgy, A.2
Brown, P.D.3
Bowry, C.4
Buckels, J.A.5
-
182
-
-
0037100983
-
A double-blind placebo-controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer
-
S.R. Bramhall, J. Schulz, J. Nemunaitis, P.D. Brown, M. Baillet, J.A. Buckels A double-blind placebo-controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer Br J Cancer 87 2002 161 167
-
(2002)
Br J Cancer
, vol.87
, pp. 161-167
-
-
Bramhall, S.R.1
Schulz, J.2
Nemunaitis, J.3
Brown, P.D.4
Baillet, M.5
Buckels, J.A.6
-
183
-
-
0141688333
-
Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
-
M.J. Moore, J. Hamm, J. Dancey, P.D. Eisenberg, M. Dagenais, A. Fields, K. Hagan, B. Greenberg, B. Colwell, B. Zee, D. Tu, J. Ottaway, R. Humphrey, L. Seymour Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas a phase III trial of the National Cancer Institute of Canada Clinical Trials Group J Clin Oncol 21 2003 3296 3302
-
(2003)
J Clin Oncol
, vol.21
, pp. 3296-3302
-
-
Moore, M.J.1
Hamm, J.2
Dancey, J.3
Eisenberg, P.D.4
Dagenais, M.5
Fields, A.6
Hagan, K.7
Greenberg, B.8
Colwell, B.9
Zee, B.10
Tu, D.11
Ottaway, J.12
Humphrey, R.13
Seymour, L.14
-
184
-
-
16444372799
-
A randomized phase III study comparing gemcitabine + pemetrexed versus gemcitabine in patients with locally advanced and metastatic pancreas cancer
-
D.A. Richards, H.L. Kindler, H. Oettle, R. Ramanathan, Laethem J.L. Van, M. Peeters, M. Fuchs, W. John, M. Arning, Hoff D. Von A randomized phase III study comparing gemcitabine + pemetrexed versus gemcitabine in patients with locally advanced and metastatic pancreas cancer (abstr 4007) Proc Am Soc Clin Oncol 23 2004
-
(2004)
Proc Am Soc Clin Oncol
, vol.23
-
-
Richards, D.A.1
Kindler, H.L.2
Oettle, H.3
Ramanathan, R.4
Van Laethem, J.L.5
Peeters, M.6
Fuchs, M.7
John, W.8
Arning, M.9
Von Hoff, D.10
-
185
-
-
0034668174
-
Inhibitors of prenylation of Ras and other G-proteins and their application as therapeutics
-
L.H. Cohen, E. Pieterman, R.E. van Leeuwen, M. Overhand, B.E. Burm, G.A. van der Marel, J.H. van Boom Inhibitors of prenylation of Ras and other G-proteins and their application as therapeutics Biochem Pharmacol 60 2000 1061 1068
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1061-1068
-
-
Cohen, L.H.1
Pieterman, E.2
Van Leeuwen, R.E.3
Overhand, M.4
Burm, B.E.5
Van Der Marel, G.A.6
Van Boom, J.H.7
-
186
-
-
2342645506
-
Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer
-
E. Van Cutsem, H. van de Velde, P. Karasek, H. Oettle, W.L. Vervenne, A. Szawlowski, P. Schoffski, S. Post, C. Verslype, H. Neumann, H. Safran, Y. Humblet, J. Perez Ruixo, Y. Ma, D.D. Von Hoff Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancer J Clin Oncol 22 2004 1430 1438
-
(2004)
J Clin Oncol
, vol.22
, pp. 1430-1438
-
-
Van Cutsem, E.1
Van De Velde, H.2
Karasek, P.3
Oettle, H.4
Vervenne, W.L.5
Szawlowski, A.6
Schoffski, P.7
Post, S.8
Verslype, C.9
Neumann, H.10
Safran, H.11
Humblet, Y.12
Perez Ruixo, J.13
Ma, Y.14
Von Hoff, D.D.15
-
187
-
-
0019350060
-
Randomized study of 5-FU and CCNU in pancreatic cancer: Report of the Veterans Administration Surgical Adjuvant Cancer Chemotherapy Study Group
-
C. Frey, P. Twomey, R. Keehn, D. Elliott, G. Higgins Randomized study of 5-FU and CCNU in pancreatic cancer report of the Veterans Administration Surgical Adjuvant Cancer Chemotherapy Study Group Cancer 47 1981 27 31
-
(1981)
Cancer
, vol.47
, pp. 27-31
-
-
Frey, C.1
Twomey, P.2
Keehn, R.3
Elliott, D.4
Higgins, G.5
-
188
-
-
0029816590
-
Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer
-
B. Glimelius, K. Hoffman, P.O. Sjoden, G. Jacobsson, H. Sellstrom, L.K. Enander, T. Linne, C. Svensson Chemotherapy improves survival and quality of life in advanced pancreatic and biliary cancer Ann Oncol 7 1996 593 600
-
(1996)
Ann Oncol
, vol.7
, pp. 593-600
-
-
Glimelius, B.1
Hoffman, K.2
Sjoden, P.O.3
Jacobsson, G.4
Sellstrom, H.5
Enander, L.K.6
Linne, T.7
Svensson, C.8
-
189
-
-
0028291349
-
Chemotherapy prolongs survival in inoperable pancreatic carcinoma
-
K.R. Palmer, M. Kerr, G. Knowles, A. Cull, D.C. Carter, R.C. Leonard Chemotherapy prolongs survival in inoperable pancreatic carcinoma Br J Surg 81 1994 882 885
-
(1994)
Br J Surg
, vol.81
, pp. 882-885
-
-
Palmer, K.R.1
Kerr, M.2
Knowles, G.3
Cull, A.4
Carter, D.C.5
Leonard, R.C.6
-
190
-
-
0242388144
-
Survival benefit of chemotherapy treatment in advanced pancreatic cancer: A meta-analysis
-
M.C. Fung, H. Ishiguro, S. Takayama, T. Morizane, S. Adachi, T. Sakata Survival benefit of chemotherapy treatment in advanced pancreatic cancer a meta-analysis (abstr 1155) Proc Am Soc Clin Oncol 22 2003
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
-
-
Fung, M.C.1
Ishiguro, H.2
Takayama, S.3
Morizane, T.4
Adachi, S.5
Sakata, T.6
-
191
-
-
0027191317
-
Chemical splanchnicectomy in patients with unresectable pancreatic cancer. A prospective randomized trial
-
K.D. Lillemoe, J.L. Cameron, H.S. Kaufman, C.J. Yeo, H.A. Pitt, P.K. Sauter Chemical splanchnicectomy in patients with unresectable pancreatic cancer. A prospective randomized trial Ann Surg 217 1993 447 455 discussion 456-457
-
(1993)
Ann Surg
, vol.217
, pp. 447-455
-
-
Lillemoe, K.D.1
Cameron, J.L.2
Kaufman, H.S.3
Yeo, C.J.4
Pitt, H.A.5
Sauter, P.K.6
-
192
-
-
1442353066
-
Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer: A randomized controlled trial
-
G.Y. Wong, D.R. Schroeder, P.E. Carns, J.L. Wilson, D.P. Martin, M.O. Kinney, C.B. Mantilla, D.O. Warner Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer a randomized controlled trial JAMA 291 2004 1092 1099
-
(2004)
JAMA
, vol.291
, pp. 1092-1099
-
-
Wong, G.Y.1
Schroeder, D.R.2
Carns, P.E.3
Wilson, J.L.4
Martin, D.P.5
Kinney, M.O.6
Mantilla, C.B.7
Warner, D.O.8
-
193
-
-
13944260238
-
Pancreatic cancer and thromboembolic disease
-
A.A. Khorana, R.L. Fine Pancreatic cancer and thromboembolic disease Lancet Oncol 5 2004 655 663
-
(2004)
Lancet Oncol
, vol.5
, pp. 655-663
-
-
Khorana, A.A.1
Fine, R.L.2
-
194
-
-
1642540356
-
Low molecular weight heparin (LMWH) increases the efficacy of cisplatinum plus gemcitabine combination in advanced pancreatic cancer
-
F. Icli, H. Akbulut, G. Utkan, D. Dincol, A. Isikdogan, A. Demirkazik, H. Onur, F. Cay, A. Buyukcelik, B. Yalcin Low molecular weight heparin (LMWH) increases the efficacy of cisplatinum plus gemcitabine combination in advanced pancreatic cancer (abstr 1149) Proc Am Soc Clin Oncol 22 2003
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
-
-
Icli, F.1
Akbulut, H.2
Utkan, G.3
Dincol, D.4
Isikdogan, A.5
Demirkazik, A.6
Onur, H.7
Cay, F.8
Buyukcelik, A.9
Yalcin, B.10
|