Epidermal growth factor and its receptor as prognostic indicators in Chinese patients with pancreatic cancer

Anticancer Research

Volumn 18, Issue 6 B, 1998, Pages 4613-4619

  Dong, Ming ^a,b   Nio, Yoshinori ^a   Guo, Ke Jian ^b   Tamura, Katsuhiro ^a   Tian, Yu Lin ^b   Dong, Yu Ting ^b  

^a SHIMANE UNIVERSITY   (Japan)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

EGF; EGFR; Epidemiology; Immunohistochemistry; Pancreatic cancer

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR;

ADULT; AGED; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CHINESE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PANCREAS CANCER; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION;

ADULT; AGED; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CHINA; EPIDERMAL GROWTH FACTOR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PANCREATIC NEOPLASMS; PROGNOSIS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SURVIVAL ANALYSIS; TIME FACTORS;

EID: 0032423809     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Lieberman MD, Paty P, Li XK, Naama H, Evoy D, Daly JM: Elevation of intracellular cyclic adenosine monophosphate inhibits the epidermal growth factor signal transduction pathway and cellular growth in pancreatic adenocarcinoma cell lines. Surg 120: 354-9, 1996.
2. Suwa H, Yoshimura T, Yamaguchi N, Kanehira K, Manabe T, Imamura M, Hiai H, Fukumoto M: K-ras and p53 alterations in genomic DNA and transcripts of human pancreatic adenocarcinoma cell lines. Jpn J Cancer Res 85: 1005-14, 1994.
3. Li LD, Zhang SW, Lu FZ: The spectrum of death and classified constitution of malignant tumors in China (Chinese). Chinese J Oncol 19:323-8, 1997.
4. Friess H, Berberat P, Schilling M, Kunz J, Korc M, Buchler MW: Pancreatic cancer: the potential clinical relevance of alterations in growth factors and their receptors. J Mol Med 74:35-42, 1996.
5. Brown KD: The epidermal growth factor/transforming growth factor alpha family and their receptors. Eur J Gastroen Hepat 7: 914-22, 1995.
6. Sporn MB, Roberts AB: Autocrine growth factors and cancer. Nature 313: 745-7, 1985.
7. Stoscheck CM, King LE: Role of epidermal growth factor in carcinogenesis. Cancer Res 46: 1030-7, 1986.
8. Yamanaka Y, Friess H, Kobrin MS, Buchler M, Beger HG, Korc M: Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced, tumor aggressiveness. Anticancer Res 13: 565-70, 1993.
9. Lemoine NR, Hughes CM, Barton CM, Poulsom R, Jeffery RE, Kloppel G, Hall PA, Gullick WJ: The epidermal growth factor receptor in human pancreatic cancer. J Pathol 166: 7-12, 1992.
10. Uegaki K, Nio Y, Inoue Y, Minari Y, Sato Y, Song MM, Dong M, Tamura K: Clinicopathological significance of epidermal growth factor and its receptor in human pancreatic cancer. Anticancer Res 17: 3841-7, 1997.
11. Dong M, Nio Y, Sato Y, Tamura K, Song MM, Tian YL, Dong YT: Comparative study of p53 expression in primary invasive ductal carcinoma of the pancreas between Chinese and Japanese. Pancreas 17: 1998. in Press.
12. Sobin LH, Wittekind Ch: TNM Classification of Malignant Tumours, 5th edition. New York, John Wiley and Sons, Inc., pp 87-90, 1997.
13. Carpenter G: Receptors for epidermal growth factor and other polypeptide mitogens. Annu Rev Biochem 56: 881-914, 1987.
14. Gullick WJ, Downward J, Parker PJ, Whittle N, Kris R, Schlessinger J, Ullrich A, Waterfield MD: The structure and function of the epidermal growth factor receptor studied by using antisynthetic peptide antibodies. Proc. R. Soc. London 226: 127-34, 1985.
15. Korc M, Chandrasekar B, Yamanaka Y, Friess H, Buchler M, Beger HG: Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha. J Clin Invest 90: 1352-60, 1992.
16. Frebourg T, Friend SH: The importance of p53 gene alterations in human cancer: Is there more than circumstantial evidence? J Natl Cancer Inst 85: 1554-7, 1993.
17. Watanabe M, Nobuta A, Tanaka J, Asaka M: An effect of K-ras gene mutation on epidermal growth factor receptor signal transduction in PANC-1 pancreatic carcinoma cells. Int J Cancer 67: 264-8, 1996.
18. Ohmura E, Okada M, Onoda N, Kamiya Y, Murakami H, Tsushima T, Shizume K: Insulin- like growth factor I and transforming growth factor alpha as autocrine growth factors in human pancreatic cancer cell growth. Cancer Res 50: 103-7, 1990.
19. Torregrosa D, Bolufer P, Lluch A, López JA, Barragán E, Ruiz A, Guillem V, Munarriz B, Garcia-Conde J: Prognostic significance of cerb B-2/neu amplification and epidermal growth factor receptor (EGFR) in primary breast cancer and their relation to estradiol receptor (ER) status. Clin Chim Acta 202: 99-119, 1997.
20. Mukaida H, Hirai T, Toi M, Nakamura T, Yamashita Y, Kawano K, Toge T, Niimoto M, Hattori T: Expression of the epidermal growth factor receptor in esophageal cancer (Japanese). Jpn J Cancer Clin 35: 1399-406, 1989.