-
1
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr JF, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26:239-257.
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
2
-
-
0142027948
-
Ways of dying: Multiple pathways to apoptosis
-
Adams JM: Ways of dying: Multiple pathways to apoptosis. Genes Dev 2003;17:2481-2495.
-
(2003)
Genes Dev
, vol.17
, pp. 2481-2495
-
-
Adams, J.M.1
-
4
-
-
0033576675
-
More than one way to die: Apoptosis, necrosis and reactive oxygen damage
-
Fiers W, Beyaert R, Declercq W, Vandenabeele P: More than one way to die: Apoptosis, necrosis and reactive oxygen damage. Oncogene 1999;18:7719-7730.
-
(1999)
Oncogene
, vol.18
, pp. 7719-7730
-
-
Fiers, W.1
Beyaert, R.2
Declercq, W.3
Vandenabeele, P.4
-
5
-
-
0038731167
-
Caspase-independent cell death in T lymphocytes
-
Jaattela M, Tschopp J: Caspase-independent cell death in T lymphocytes. Nat Immunol 2003;4:416-423.
-
(2003)
Nat Immunol
, vol.4
, pp. 416-423
-
-
Jaattela, M.1
Tschopp, J.2
-
6
-
-
0033280669
-
Biochemical pathways of caspase activation during apoptosis
-
Budihardjo I, Oliver H, Lutter M, Luo X, Wang X: Biochemical pathways of caspase activation during apoptosis. Annu Rev Cell Dev Biol 1999;15:269-290.
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 269-290
-
-
Budihardjo, I.1
Oliver, H.2
Lutter, M.3
Luo, X.4
Wang, X.5
-
7
-
-
0344389027
-
Caspases: The proteases of the apoptotic pathway
-
Nunez G, Benedict MA, Hu Y, Inohara N: Caspases: The proteases of the apoptotic pathway. Oncogene 1998;17:3237-3245.
-
(1998)
Oncogene
, vol.17
, pp. 3237-3245
-
-
Nunez, G.1
Benedict, M.A.2
Hu, Y.3
Inohara, N.4
-
8
-
-
0034630161
-
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems
-
Walczak H, Krammer PH: The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp Cell Res 2000;256:58-66.
-
(2000)
Exp Cell Res
, vol.256
, pp. 58-66
-
-
Walczak, H.1
Krammer, P.H.2
-
9
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi C, Fulda S, Srinivasan A, Friesen C, Li F, Tomaselli KJ, Debatin KM, Krammer PH, Peter ME: Two CD95 (APO-1/Fas) signaling pathways. EMBO J 1998;17:1675-1687.
-
(1998)
EMBO J
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
Debatin, K.M.7
Krammer, P.H.8
Peter, M.E.9
-
11
-
-
0037427412
-
Mechanisms of cytochrome c release by proapoptotic BCL-2 family members
-
Scorrano L, Korsmeyer SJ: Mechanisms of cytochrome c release by proapoptotic BCL-2 family members. Biochem Biophys Res Commun 2003;304:437-444.
-
(2003)
Biochem Biophys Res Commun
, vol.304
, pp. 437-444
-
-
Scorrano, L.1
Korsmeyer, S.J.2
-
12
-
-
0034117177
-
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis
-
Daugas E, Susin SA, Zamzami N, Ferri KF, Irinopoulou T, Larochette N, Prevost MC, Leber B, Andrews D, Penninger J, Kroemer G: Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. FASEB J 2000;14:729-739.
-
(2000)
FASEB J
, vol.14
, pp. 729-739
-
-
Daugas, E.1
Susin, S.A.2
Zamzami, N.3
Ferri, K.F.4
Irinopoulou, T.5
Larochette, N.6
Prevost, M.C.7
Leber, B.8
Andrews, D.9
Penninger, J.10
Kroemer, G.11
-
13
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X: Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
16
-
-
0033400223
-
Pathophysiology of mitochondrial cell death control
-
Vieira HL, Kroemer G: Pathophysiology of mitochondrial cell death control. Cell Mol Life Sci 1999;56:971-976.
-
(1999)
Cell Mol Life Sci
, vol.56
, pp. 971-976
-
-
Vieira, H.L.1
Kroemer, G.2
-
17
-
-
0037427443
-
Mitochondrial membrane permeabilisation by Bax/Bak
-
Degli EM, Dive C: Mitochondrial membrane permeabilisation by Bax/Bak. Biochem Biophys Res Commun 2003;304:455-461.
-
(2003)
Biochem Biophys Res Commun
, vol.304
, pp. 455-461
-
-
Degli, E.M.1
Dive, C.2
-
18
-
-
0032422488
-
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
-
Narita M, Shimizu S, Ito T, Chittenden T, Lutz RJ, Matsuda H, Tsujimoto Y: Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proc Natl Acad Sci USA 1998;95:14681-14686.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 14681-14686
-
-
Narita, M.1
Shimizu, S.2
Ito, T.3
Chittenden, T.4
Lutz, R.J.5
Matsuda, H.6
Tsujimoto, Y.7
-
19
-
-
0034523818
-
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
-
Korsmeyer SJ, Wei MC, Saito M, Weiler S, Oh KJ, Schlesinger PH: Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ 2000;7:1166-1173.
-
(2000)
Cell Death Differ
, vol.7
, pp. 1166-1173
-
-
Korsmeyer, S.J.1
Wei, M.C.2
Saito, M.3
Weiler, S.4
Oh, K.J.5
Schlesinger, P.H.6
-
20
-
-
0037115740
-
Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein
-
Roucou X, Montessuit S, Antonsson B, Martinou JC: Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein. Biochem J 2002;368:915-921.
-
(2002)
Biochem J
, vol.368
, pp. 915-921
-
-
Roucou, X.1
Montessuit, S.2
Antonsson, B.3
Martinou, J.C.4
-
21
-
-
0035433420
-
Four deaths and a funeral: From caspases to alternative mechanisms
-
Leist M, Jaattela M: Four deaths and a funeral: From caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2001;2:589-598.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 589-598
-
-
Leist, M.1
Jaattela, M.2
-
22
-
-
0035947776
-
Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor
-
Foghsgaard L, Wissing D, Mauch D, Lademann U, Bastholm L, Boes M, Elling F, Leist M, Jaattela M: Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. J Cell Biol 2001;153:999-1010.
-
(2001)
J Cell Biol
, vol.153
, pp. 999-1010
-
-
Foghsgaard, L.1
Wissing, D.2
Mauch, D.3
Lademann, U.4
Bastholm, L.5
Boes, M.6
Elling, F.7
Leist, M.8
Jaattela, M.9
-
23
-
-
0033756474
-
Cathepsin B contributes to TNF-α-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
-
Guicciardi ME, Deussing J, Miyoshi H, Bronk SF, Svingen PA, Peters C, Kaufmann SH, Gores GJ: Cathepsin B contributes to TNF-α-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J Clin Invest 2000;106:1127-1137.
-
(2000)
J Clin Invest
, vol.106
, pp. 1127-1137
-
-
Guicciardi, M.E.1
Deussing, J.2
Miyoshi, H.3
Bronk, S.F.4
Svingen, P.A.5
Peters, C.6
Kaufmann, S.H.7
Gores, G.J.8
-
24
-
-
0043234207
-
Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor relocation in T lymphocytes entering the early commitment phase to apoptosis
-
Bidere N, Lorenzo HK, Carmona S, Laforge M, Harper F, Dumont C, Senik A: Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor relocation in T lymphocytes entering the early commitment phase to apoptosis. J Biol Chem 2003;278:31401-31411.
-
(2003)
J Biol Chem
, vol.278
, pp. 31401-31411
-
-
Bidere, N.1
Lorenzo, H.K.2
Carmona, S.3
Laforge, M.4
Harper, F.5
Dumont, C.6
Senik, A.7
-
25
-
-
0035793580
-
Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route
-
Stoka V, Turk B, Schendel SL, Kim TH, Cirman T, Snipas SJ, Ellerby LM, Bredesen D, Freeze H, Abrahamson M, Bromme D, Krajewski S, Reed JC, Yin XM, Turk V, Salvesen GS: Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route. J Biol Chem 2001;276:3149-3157.
-
(2001)
J Biol Chem
, vol.276
, pp. 3149-3157
-
-
Stoka, V.1
Turk, B.2
Schendel, S.L.3
Kim, T.H.4
Cirman, T.5
Snipas, S.J.6
Ellerby, L.M.7
Bredesen, D.8
Freeze, H.9
Abrahamson, M.10
Bromme, D.11
Krajewski, S.12
Reed, J.C.13
Yin, X.M.14
Turk, V.15
Salvesen, G.S.16
-
26
-
-
0032898002
-
Calpain mediates ischemic injury of the liver through modulation of apoptosis and necrosis
-
Kohli V, Madden JF, Bentley RC, Clavien PA: Calpain mediates ischemic injury of the liver through modulation of apoptosis and necrosis. Gastroenterology 1999;116:168-178.
-
(1999)
Gastroenterology
, vol.116
, pp. 168-178
-
-
Kohli, V.1
Madden, J.F.2
Bentley, R.C.3
Clavien, P.A.4
-
27
-
-
0033956278
-
Calpain and caspase: Can you tell the difference?
-
Wang KK: Calpain and caspase: Can you tell the difference? Trends Neurosci 2000;23:20-26.
-
(2000)
Trends Neurosci
, vol.23
, pp. 20-26
-
-
Wang, K.K.1
-
28
-
-
1242316976
-
Calpain-1 regulates Bax and subsequent Smac-dependent caspase-3 activation in neutrophil apoptosis
-
Altznauer F, Conus S, Cavalli A, Folkers G, Simon HU: Calpain-1 regulates Bax and subsequent Smac-dependent caspase-3 activation in neutrophil apoptosis. J Biol Chem 2004;279:5947-5957.
-
(2004)
J Biol Chem
, vol.279
, pp. 5947-5957
-
-
Altznauer, F.1
Conus, S.2
Cavalli, A.3
Folkers, G.4
Simon, H.U.5
-
30
-
-
0030915587
-
Intracellular ATP levels determine cell death fate by apoptosis or necrosis
-
Eguchi Y, Shimizu S, Tsujimoto Y: Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res 1997;57:1835-1840.
-
(1997)
Cancer Res
, vol.57
, pp. 1835-1840
-
-
Eguchi, Y.1
Shimizu, S.2
Tsujimoto, Y.3
-
31
-
-
0032437405
-
Intracellular ATP, a switch in the decision between apoptosis and necrosis
-
Nicotera P, Leist M, Ferrando-May E: Intracellular ATP, a switch in the decision between apoptosis and necrosis. Toxicol Lett 1998;102-103:139-142.
-
(1998)
Toxicol Lett
, vol.102-103
, pp. 139-142
-
-
Nicotera, P.1
Leist, M.2
Ferrando-May, E.3
-
32
-
-
0033964762
-
Mitochondrial role in life and death of the cell
-
Lee HC, Wei YH: Mitochondrial role in life and death of the cell. J Biomed Sci 2000;7:2-15.
-
(2000)
J Biomed Sci
, vol.7
, pp. 2-15
-
-
Lee, H.C.1
Wei, Y.H.2
-
33
-
-
0030826778
-
Cyclosporin a binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury
-
Halestrap AP, Connern CP, Griffiths EJ, Kerr PM: Cyclosporin A binding to mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury. Mol Cell Biochem 1997;174:167-172.
-
(1997)
Mol Cell Biochem
, vol.174
, pp. 167-172
-
-
Halestrap, A.P.1
Connern, C.P.2
Griffiths, E.J.3
Kerr, P.M.4
-
34
-
-
0033400542
-
Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death
-
Lemasters JJ, Qian T, Bradham CA, Brenner DA, Cascio WE, Trost LC, Nishimura Y, Nieminen AL, Herman B: Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death. J Bioenerg Biomembr 1999;31:305-319.
-
(1999)
J Bioenerg Biomembr
, vol.31
, pp. 305-319
-
-
Lemasters, J.J.1
Qian, T.2
Bradham, C.A.3
Brenner, D.A.4
Cascio, W.E.5
Trost, L.C.6
Nishimura, Y.7
Nieminen, A.L.8
Herman, B.9
-
35
-
-
0021112635
-
Poly(ADP-ribose) polymerase inhibitors preserve nicotinamide adenine dinucleotide and adenosine 5′-triphosphate pools in DNA-damaged cells: Mechanism of stimulation of unscheduled DNA synthesis
-
Sims JL, Berger SJ, Berger NA: Poly(ADP-ribose) polymerase inhibitors preserve nicotinamide adenine dinucleotide and adenosine 5′-triphosphate pools in DNA-damaged cells: Mechanism of stimulation of unscheduled DNA synthesis. Biochemistry 1983;22:5188-5194.
-
(1983)
Biochemistry
, vol.22
, pp. 5188-5194
-
-
Sims, J.L.1
Berger, S.J.2
Berger, N.A.3
-
36
-
-
0022492499
-
DNA strand breaks, NAD metabolism, and programmed cell death
-
Carson DA, Seto S, Wasson DB, Carrera CJ: DNA strand breaks, NAD metabolism, and programmed cell death. Exp Cell Res 1986;164:273-281.
-
(1986)
Exp Cell Res
, vol.164
, pp. 273-281
-
-
Carson, D.A.1
Seto, S.2
Wasson, D.B.3
Carrera, C.J.4
-
37
-
-
0033598713
-
Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
-
Ha HC, Snyder SH: Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc Natl Acad Sci USA 1999;96:13978-13982.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13978-13982
-
-
Ha, H.C.1
Snyder, S.H.2
-
38
-
-
0032999788
-
Poly(ADP-ribose) polymerase, nitric oxide and cell death
-
Pieper AA, Verma A, Zhang J, Snyder SH: Poly(ADP-ribose) polymerase, nitric oxide and cell death. Trends Pharmacol Sci 1999;20:171-181.
-
(1999)
Trends Pharmacol Sci
, vol.20
, pp. 171-181
-
-
Pieper, A.A.1
Verma, A.2
Zhang, J.3
Snyder, S.H.4
-
39
-
-
0035063766
-
Pharmacologic inhibition of poly( ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats
-
LaPlaca MC, Zhang J, Raghupathi R, Li JH, Smith F, Bareyre FM, Snyder SH, Graham DI, McIntosh TK: Pharmacologic inhibition of poly( ADP-ribose) polymerase is neuroprotective following traumatic brain injury in rats. J Neurotrauma 2001;18:369-376.
-
(2001)
J Neurotrauma
, vol.18
, pp. 369-376
-
-
LaPlaca, M.C.1
Zhang, J.2
Raghupathi, R.3
Li, J.H.4
Smith, F.5
Bareyre, F.M.6
Snyder, S.H.7
Graham, D.I.8
McIntosh, T.K.9
-
41
-
-
0034730142
-
Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase
-
Liaudet L, Soriano FG, Szabo E, Virag L, Mabley JG, Salzman AL, Szabo C: Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase. Proc Natl Acad Sci USA 2000;97:10203-10208.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10203-10208
-
-
Liaudet, L.1
Soriano, F.G.2
Szabo, E.3
Virag, L.4
Mabley, J.G.5
Salzman, A.L.6
Szabo, C.7
-
42
-
-
0033003004
-
Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis
-
Herceg Z, Wang ZQ: Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis. Mol Cell Biol 1999;19:5124-5133.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5124-5133
-
-
Herceg, Z.1
Wang, Z.Q.2
-
43
-
-
0031822063
-
Peroxynitrite-induced thymocyte apoptosis: The role of caspases and poly(ADP-ribose) synthetase activation
-
Virag L, Scott GS, Cuzzocrea S, Marmer D, Salzman AL, Szabo C: Peroxynitrite-induced thymocyte apoptosis: The role of caspases and poly(ADP-ribose) synthetase activation. Immunology 1998;94:345-355.
-
(1998)
Immunology
, vol.94
, pp. 345-355
-
-
Virag, L.1
Scott, G.S.2
Cuzzocrea, S.3
Marmer, D.4
Salzman, A.L.5
Szabo, C.6
-
44
-
-
0030615201
-
Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes PJ, Karin M: Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 1997;336:1066-1071.
-
(1997)
N Engl J Med
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
45
-
-
0034668151
-
Apoptosis and nuclear factor-κB: A tale of association and dissociation
-
Aggarwal BB: Apoptosis and nuclear factor-κB: A tale of association and dissociation. Biochem Pharmacol 2000;60:1033-1039.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1033-1039
-
-
Aggarwal, B.B.1
-
46
-
-
0036009115
-
NF-κB at the crossroads of life and death
-
Karin M, Lin A: NF-κB at the crossroads of life and death. Nat Immunol 2002;3:221-227.
-
(2002)
Nat Immunol
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
47
-
-
1642553460
-
To be, or not to be: NF-κB is the answer - Role of Rel/NF-κB in the regulation of apoptosis
-
Kucharczak J, Simmons MJ, Fan Y, Gelinas C: To be, or not to be: NF-κB is the answer - Role of Rel/NF-κB in the regulation of apoptosis. Oncogene 2003;22:8961-8982.
-
(2003)
Oncogene
, vol.22
, pp. 8961-8982
-
-
Kucharczak, J.1
Simmons, M.J.2
Fan, Y.3
Gelinas, C.4
-
48
-
-
0033082995
-
IAP family proteins - Suppressors of apoptosis
-
Deveraux QL, Reed JC: IAP family proteins - Suppressors of apoptosis. Genes Dev 1999;13:239-252.
-
(1999)
Genes Dev
, vol.13
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
50
-
-
0030907987
-
PI3K: Downstream AKTion blocks apoptosis
-
Franke TF, Kaplan DR, Cantley LC: PI3K: downstream AKTion blocks apoptosis. Cell 1997;88:435-437.
-
(1997)
Cell
, vol.88
, pp. 435-437
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
-
51
-
-
0036629251
-
Cell cycle and death control: Long live forkheads
-
Burgering BM, Kops GJ: Cell cycle and death control: Long live forkheads. Trends Biochem Sci 2002;27:352-360.
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 352-360
-
-
Burgering, B.M.1
Kops, G.J.2
-
53
-
-
0030584088
-
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
-
Zha J, Harada H, Yang E, Jockel J, Korsmeyer SJ: Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L). Cell 1996;87:619-628.
-
(1996)
Cell
, vol.87
, pp. 619-628
-
-
Zha, J.1
Harada, H.2
Yang, E.3
Jockel, J.4
Korsmeyer, S.J.5
-
54
-
-
0038668000
-
Escaping cell death: Survival proteins in cancer
-
Jaattela M: Escaping cell death: Survival proteins in cancer. Exp Cell Res 1999;248:30-43.
-
(1999)
Exp Cell Res
, vol.248
, pp. 30-43
-
-
Jaattela, M.1
-
55
-
-
0034605446
-
Role of the heat shock response and molecular chaperones in oncogenesis and cell death
-
Jolly C, Morimoto RI: Role of the heat shock response and molecular chaperones in oncogenesis and cell death. J Natl Cancer Inst 2000;92:1564-1572.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1564-1572
-
-
Jolly, C.1
Morimoto, R.I.2
-
56
-
-
0028905823
-
Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery
-
Plumier JC, Ross BM, Currie RW, Angelidis CE, Kazlaris H, Kollias G, Pagoulatos GN: Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recovery. J Clin Invest 1995;95:1854-1860.
-
(1995)
J Clin Invest
, vol.95
, pp. 1854-1860
-
-
Plumier, J.C.1
Ross, B.M.2
Currie, R.W.3
Angelidis, C.E.4
Kazlaris, H.5
Kollias, G.6
Pagoulatos, G.N.7
-
57
-
-
0028932259
-
Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury
-
Marber MS, Mestril R, Chi SH, Sayen MR, Yellon DM, Dillmann WH: Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J Clin Invest 1995;95:1446-1456.
-
(1995)
J Clin Invest
, vol.95
, pp. 1446-1456
-
-
Marber, M.S.1
Mestril, R.2
Chi, S.H.3
Sayen, M.R.4
Yellon, D.M.5
Dillmann, W.H.6
-
58
-
-
0029794271
-
Overexpression of heat shock protein 72 in transgenic mice decreases infarct size in vivo
-
Hutter JJ, Mestril R, Tam EK, Sievers RE, Dillmann WH, Wolfe CL: Overexpression of heat shock protein 72 in transgenic mice decreases infarct size in vivo. Circulation 1996;94:1408-1411.
-
(1996)
Circulation
, vol.94
, pp. 1408-1411
-
-
Hutter, J.J.1
Mestril, R.2
Tam, E.K.3
Sievers, R.E.4
Dillmann, W.H.5
Wolfe, C.L.6
-
59
-
-
9244263563
-
Cardioprotective effects of 70-kDa heat shock protein in transgenic mice
-
Radford NB, Fina M, Benjamin IJ, Moreadith RW, Graves KH, Zhao P, Gavva S, Wiethoff A, Sherry AD, Malloy CR, Williams RS: Cardioprotective effects of 70-kDa heat shock protein in transgenic mice. Proc Natl Acad Sci USA 1996;93:2339-2342.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2339-2342
-
-
Radford, N.B.1
Fina, M.2
Benjamin, I.J.3
Moreadith, R.W.4
Graves, K.H.5
Zhao, P.6
Gavva, S.7
Wiethoff, A.8
Sherry, A.D.9
Malloy, C.R.10
Williams, R.S.11
-
60
-
-
0035211413
-
Targeted Hsp70.1 disruption increases infarction volume after focal cerebral ischemia in mice
-
Lee SH, Kim M, Yoon BW, Kim YJ, Ma SJ, Roh JK, Lee JS, Seo JS: Targeted Hsp70.1 disruption increases infarction volume after focal cerebral ischemia in mice. Stroke 2001;32:2905-2912.
-
(2001)
Stroke
, vol.32
, pp. 2905-2912
-
-
Lee, S.H.1
Kim, M.2
Yoon, B.W.3
Kim, Y.J.4
Ma, S.J.5
Roh, J.K.6
Lee, J.S.7
Seo, J.S.8
-
61
-
-
0037427476
-
Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways
-
Parcellier A, Gurbuxani S, Schmitt E, Solary E, Garrido C: Heat shock proteins, cellular chaperones that modulate mitochondrial cell death pathways. Biochem Biophys Res Commun 2003;304:505-512.
-
(2003)
Biochem Biophys Res Commun
, vol.304
, pp. 505-512
-
-
Parcellier, A.1
Gurbuxani, S.2
Schmitt, E.3
Solary, E.4
Garrido, C.5
-
63
-
-
0037418861
-
Cell biology. Apoptosis - The calcium connection
-
Demaurex N, Distelhorst C: Cell biology. Apoptosis - The calcium connection. Science 2003;300:65-67.
-
(2003)
Science
, vol.300
, pp. 65-67
-
-
Demaurex, N.1
Distelhorst, C.2
-
65
-
-
0036877142
-
The endoplasmic reticulum: A multifunctional signaling organelle
-
Berridge MJ: The endoplasmic reticulum: A multifunctional signaling organelle. Cell Calcium 2002;32:235-249.
-
(2002)
Cell Calcium
, vol.32
, pp. 235-249
-
-
Berridge, M.J.1
-
66
-
-
0344825875
-
Cytochrome c binds to inositol-1,4,5-trisphosphate receptors, amplifying calcium-dependent apoptosis
-
Boehning D, Patterson RL, Sedaghat L, Glebova NO, Kurosaki T, Snyder SH: Cytochrome c binds to inositol-1,4,5-trisphosphate receptors, amplifying calcium-dependent apoptosis. Nat Cell Biol 2003;5:1051-1061.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 1051-1061
-
-
Boehning, D.1
Patterson, R.L.2
Sedaghat, L.3
Glebova, N.O.4
Kurosaki, T.5
Snyder, S.H.6
-
67
-
-
0035282926
-
Ceramide-induced cell death in the prostate cancer cell line LNCaP has both necrotic and apoptotic features
-
Engedal N, Saatcioglu F: Ceramide-induced cell death in the prostate cancer cell line LNCaP has both necrotic and apoptotic features. Prostate 2001;46:289-297.
-
(2001)
Prostate
, vol.46
, pp. 289-297
-
-
Engedal, N.1
Saatcioglu, F.2
-
68
-
-
0032995916
-
Ceramide induces caspase-independent apoptosis in rat hepatocytes sensitized by inhibition of RNA synthesis
-
Jones BE, Lo CR, Srinivasan A, Valentino KL, Czaja MJ: Ceramide induces caspase-independent apoptosis in rat hepatocytes sensitized by inhibition of RNA synthesis. Hepatology 1999;30:215-222.
-
(1999)
Hepatology
, vol.30
, pp. 215-222
-
-
Jones, B.E.1
Lo, C.R.2
Srinivasan, A.3
Valentino, K.L.4
Czaja, M.J.5
-
70
-
-
0037312820
-
Ceramide increases mitochondrial free calcium levels via caspase 8 and Bid: Role in initiation of cell death
-
Darios F, Lambeng N, Troadec JD, Michel PP, Ruberg M: Ceramide increases mitochondrial free calcium levels via caspase 8 and Bid: Role in initiation of cell death. J Neurochem 2003;84:643-654.
-
(2003)
J Neurochem
, vol.84
, pp. 643-654
-
-
Darios, F.1
Lambeng, N.2
Troadec, J.D.3
Michel, P.P.4
Ruberg, M.5
-
71
-
-
18344394549
-
Bcl-2 overexpression prevents apoptosis induced by ceramidase inhibitors in malignant melanoma and HaCaT keratinocytes
-
Raisova M, Goltz G, Bektas M, Bielawska A, Riebeling C, Hossini AM, Eberle J, Hannun YA, Orfanos CE, Geilen CC: Bcl-2 overexpression prevents apoptosis induced by ceramidase inhibitors in malignant melanoma and HaCaT keratinocytes. FEBS Lett 2002;516:47-52.
-
(2002)
FEBS Lett
, vol.516
, pp. 47-52
-
-
Raisova, M.1
Goltz, G.2
Bektas, M.3
Bielawska, A.4
Riebeling, C.5
Hossini, A.M.6
Eberle, J.7
Hannun, Y.A.8
Orfanos, C.E.9
Geilen, C.C.10
-
72
-
-
0036260697
-
Cellular response to oxidative stress: Signaling for suicide and survival
-
Martindale JL, Holbrook NJ: Cellular response to oxidative stress: Signaling for suicide and survival. J Cell Physiol 2002;192:1-15.
-
(2002)
J Cell Physiol
, vol.192
, pp. 1-15
-
-
Martindale, J.L.1
Holbrook, N.J.2
-
73
-
-
0033538451
-
Oxidative stress inhibits apoptosis in human lymphoma cells
-
Lee YJ, Shacter E: Oxidative stress inhibits apoptosis in human lymphoma cells. J Biol Chem 1999;274:19792-19798.
-
(1999)
J Biol Chem
, vol.274
, pp. 19792-19798
-
-
Lee, Y.J.1
Shacter, E.2
-
74
-
-
0033807445
-
Hydrogen peroxide inhibits activation, not activity, of cellular caspase-3 in vivo
-
Lee YJ, Shacter E: Hydrogen peroxide inhibits activation, not activity, of cellular caspase-3 in vivo. Free Radic Biol Med 2000;29:684-692.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 684-692
-
-
Lee, Y.J.1
Shacter, E.2
-
75
-
-
0002068962
-
Acute pancreatitis
-
Yamada T, Alpers DH, Laine L, Owyang C, Powell DW (eds): Philadelphia, Lippincott Williams & Wilkins
-
Topanzian M, Gorelick FS: Acute pancreatitis; in Yamada T, Alpers DH, Laine L, Owyang C, Powell DW (eds): Textbook of Gastroenterology. Philadelphia, Lippincott Williams & Wilkins, 1999, pp 2121-2150.
-
(1999)
Textbook of Gastroenterology
, pp. 2121-2150
-
-
Topanzian, M.1
Gorelick, F.S.2
-
76
-
-
0034077468
-
Early trypsinogen activation in acute pancreatitis
-
Lerch MM, Gorelick FS: Early trypsinogen activation in acute pancreatitis. Med Clin North Am 2000;84:549-563, viii.
-
(2000)
Med Clin North Am
, vol.84
, pp. 549-563
-
-
Lerch, M.M.1
Gorelick, F.S.2
-
78
-
-
30444432737
-
Apoptosis in acute pancreatitis
-
He ZJ, Podkletnova I, Alho H, Sand J, Nordback I: Apoptosis in acute pancreatitis. Ann Chir Gynaecol 2000;89:65-67.
-
(2000)
Ann Chir Gynaecol
, vol.89
, pp. 65-67
-
-
He, Z.J.1
Podkletnova, I.2
Alho, H.3
Sand, J.4
Nordback, I.5
-
79
-
-
0023151584
-
Ultrastructure of the rat pancreas after experimental duct ligation. I. The role of apoptosis and intraepithelial macrophages in acinar cell deletion
-
Walker NI: Ultrastructure of the rat pancreas after experimental duct ligation. I. The role of apoptosis and intraepithelial macrophages in acinar cell deletion. Am J Pathol 1987;126:439-451.
-
(1987)
Am J Pathol
, vol.126
, pp. 439-451
-
-
Walker, N.I.1
-
80
-
-
0026693159
-
Ultrastructure of the rat pancreas after experimental duct ligation. II. Duct and stromal cell proliferation, differentiation, and deletion
-
Walker NI, Winterford CM, Kerr JF: Ultrastructure of the rat pancreas after experimental duct ligation. II. Duct and stromal cell proliferation, differentiation, and deletion. Pancreas 1992;7:420-434.
-
(1992)
Pancreas
, vol.7
, pp. 420-434
-
-
Walker, N.I.1
Winterford, C.M.2
Kerr, J.F.3
-
81
-
-
0030025675
-
Mechanisms of cell death after pancreatic duct obstruction in the opossum and the rat
-
Gukovskaya AS, Perkins P, Zaninovic V, Sandoval D, Rutherford R, Fitzsimmons T, Pandol SJ, Poucell-Hatton S: Mechanisms of cell death after pancreatic duct obstruction in the opossum and the rat. Gastroenterology 1996;110:875-884.
-
(1996)
Gastroenterology
, vol.110
, pp. 875-884
-
-
Gukovskaya, A.S.1
Perkins, P.2
Zaninovic, V.3
Sandoval, D.4
Rutherford, R.5
Fitzsimmons, T.6
Pandol, S.J.7
Poucell-Hatton, S.8
-
82
-
-
0028783295
-
Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis
-
Kaiser AM, Saluja AK, Sengupta A, Saluja M, Steer ML: Relationship between severity, necrosis, and apoptosis in five models of experimental acute pancreatitis. Am J Physiol 1995;269:C1295-C1304.
-
(1995)
Am J Physiol
, vol.269
-
-
Kaiser, A.M.1
Saluja, A.K.2
Sengupta, A.3
Saluja, M.4
Steer, M.L.5
-
83
-
-
0032803557
-
Cytokine expression and induction of acinar cell apoptosis after pancreatic duct ligation in mice
-
Yasuda H, Kataoka K, Ichimura H, Mitsuyoshi M, Iida T, Kita M, Imanishi J: Cytokine expression and induction of acinar cell apoptosis after pancreatic duct ligation in mice. J Interferon Cytokine Res 1999;19:637-644.
-
(1999)
J Interferon Cytokine Res
, vol.19
, pp. 637-644
-
-
Yasuda, H.1
Kataoka, K.2
Ichimura, H.3
Mitsuyoshi, M.4
Iida, T.5
Kita, M.6
Imanishi, J.7
-
84
-
-
0034939465
-
Differential effects of caspase-1/interleukin-1β-converting enzyme on acinar cell necrosis and apoptosis in severe acute experimental pancreatitis
-
Rau B, Paszkowski A, Lillich S, Baumgart K, Moller P, Beger HG: Differential effects of caspase-1/interleukin-1β-converting enzyme on acinar cell necrosis and apoptosis in severe acute experimental pancreatitis. Lab Invest 2001;81:1001-1013.
-
(2001)
Lab Invest
, vol.81
, pp. 1001-1013
-
-
Rau, B.1
Paszkowski, A.2
Lillich, S.3
Baumgart, K.4
Moller, P.5
Beger, H.G.6
-
85
-
-
0030800825
-
Ischemia-reperfusion injury on the pancreas in rats: Identification of acinar cell apoptosis
-
Fujimoto K, Hosotani R, Wada M, Lee J, Koshiba T, Miyamoto Y, Doi R, Imamura M: Ischemia-reperfusion injury on the pancreas in rats: Identification of acinar cell apoptosis. J Surg Res 1997;71:127-136.
-
(1997)
J Surg Res
, vol.71
, pp. 127-136
-
-
Fujimoto, K.1
Hosotani, R.2
Wada, M.3
Lee, J.4
Koshiba, T.5
Miyamoto, Y.6
Doi, R.7
Imamura, M.8
-
86
-
-
0037309879
-
Severe acute pancreatitis and reduced acinar cell apoptosis in the exocrine pancreas of mice deficient for the Cx32 gene
-
Frossard JL, Rubbia-Brandt L, Wallig MA, Benathan M, Ott T, Morel P, Hadengue A, Suter S, Willecke K, Chanson M: Severe acute pancreatitis and reduced acinar cell apoptosis in the exocrine pancreas of mice deficient for the Cx32 gene. Gastroenterology 2003;124:481-493.
-
(2003)
Gastroenterology
, vol.124
, pp. 481-493
-
-
Frossard, J.L.1
Rubbia-Brandt, L.2
Wallig, M.A.3
Benathan, M.4
Ott, T.5
Morel, P.6
Hadengue, A.7
Suter, S.8
Willecke, K.9
Chanson, M.10
-
87
-
-
0033710733
-
P53-dependent acinar cell apoptosis triggers epithelial proliferation in duct-ligated murine pancreas
-
Scoggins CR, Meszoely IM, Wada M, Means AL, Yang L, Leach SD: p53-dependent acinar cell apoptosis triggers epithelial proliferation in duct-ligated murine pancreas. Am J Physiol 2000;279:G827-G836.
-
(2000)
Am J Physiol
, vol.279
-
-
Scoggins, C.R.1
Meszoely, I.M.2
Wada, M.3
Means, A.L.4
Yang, L.5
Leach, S.D.6
-
88
-
-
0034942714
-
Acute pancreatitis signals activation of apoptosis-associated and survival genes in mice
-
Gomez G, Lee HM, He Q, Englander EW, Uchida T, Greeley GH Jr: Acute pancreatitis signals activation of apoptosis-associated and survival genes in mice. Exp Biol Med 2001;226:692-700.
-
(2001)
Exp Biol Med
, vol.226
, pp. 692-700
-
-
Gomez, G.1
Lee, H.M.2
He, Q.3
Englander, E.W.4
Uchida, T.5
Greeley Jr., G.H.6
-
89
-
-
0035554145
-
Detailed tissue expression of bcl-2, bax, bak and bcl-x in the normal human pancreas and in chronic pancreatitis, ampullary and pancreatic ductal adenocarcinomas
-
Evans JD, Cornford PA, Dodson A, Greenhalf W, Foster CS, Neoptolemos JP: Detailed tissue expression of bcl-2, bax, bak and bcl-x in the normal human pancreas and in chronic pancreatitis, ampullary and pancreatic ductal adenocarcinomas. Pancreatology 2001;1:254-262.
-
(2001)
Pancreatology
, vol.1
, pp. 254-262
-
-
Evans, J.D.1
Cornford, P.A.2
Dodson, A.3
Greenhalf, W.4
Foster, C.S.5
Neoptolemos, J.P.6
-
90
-
-
0037151017
-
Cholecystokinin induces caspase activation and mitochondrial dysfunction in pancreatic acinar cells. Roles in cell injury processes of pancreatitis
-
Gukovskaya AS, Gukovsky I, Jung Y, Mouria M, Pandol SJ: Cholecystokinin induces caspase activation and mitochondrial dysfunction in pancreatic acinar cells. Roles in cell injury processes of pancreatitis. J Biol Chem 2002;277:22595-22604.
-
(2002)
J Biol Chem
, vol.277
, pp. 22595-22604
-
-
Gukovskaya, A.S.1
Gukovsky, I.2
Jung, Y.3
Mouria, M.4
Pandol, S.J.5
-
91
-
-
0030923560
-
Pancreatic acinar cells produce, release, and respond to tumor necrosis factor-a. Role in regulating cell death and pancreatitis
-
Gukovskaya AS, Gukovsky I, Zaninovic V, Song M, Sandoval D, Gukovsky S, Pandol SJ: Pancreatic acinar cells produce, release, and respond to tumor necrosis factor-a. Role in regulating cell death and pancreatitis. J Clin Invest 1997;100:1853-1862.
-
(1997)
J Clin Invest
, vol.100
, pp. 1853-1862
-
-
Gukovskaya, A.S.1
Gukovsky, I.2
Zaninovic, V.3
Song, M.4
Sandoval, D.5
Gukovsky, S.6
Pandol, S.J.7
-
92
-
-
0029993964
-
Lipopolysaccharide induced apoptosis of rat pancreatic acinar cells
-
Laine VJ, Nyman KM, Peuravuori HJ, Henriksen K, Parvinen M, Nevalainen TJ: Lipopolysaccharide induced apoptosis of rat pancreatic acinar cells. Gut 1996;38:747-752.
-
(1996)
Gut
, vol.38
, pp. 747-752
-
-
Laine, V.J.1
Nyman, K.M.2
Peuravuori, H.J.3
Henriksen, K.4
Parvinen, M.5
Nevalainen, T.J.6
-
93
-
-
0031817371
-
Low doses of lipopolysaccharide upregulate acinar cell apoptosis in cerulein pancreatitis
-
Kimura K, Shimosegawa T, Abe R, Masamune A, Satoh A, Takasu A, Koizumi M, Toyota T: Low doses of lipopolysaccharide upregulate acinar cell apoptosis in cerulein pancreatitis. Pancreas 1998;17:120-126.
-
(1998)
Pancreas
, vol.17
, pp. 120-126
-
-
Kimura, K.1
Shimosegawa, T.2
Abe, R.3
Masamune, A.4
Satoh, A.5
Takasu, A.6
Koizumi, M.7
Toyota, T.8
-
94
-
-
0037225477
-
Curcumin ameliorates ethanol and nonethanol experimental pancreatitis
-
Gukovsky I, Reyes CN, Vaquero EC, Gukovskaya AS, Pandol SJ: Curcumin ameliorates ethanol and nonethanol experimental pancreatitis. Am J Physiol 2003;284:G85-G95.
-
(2003)
Am J Physiol
, vol.284
-
-
Gukovsky, I.1
Reyes, C.N.2
Vaquero, E.C.3
Gukovskaya, A.S.4
Pandol, S.J.5
-
95
-
-
11844289329
-
Caspases and poly(ADP-ribose) polymerase regulate the balance between apoptosis and necrosis in experimental pancreatitis
-
Gukovsky I, Nam K, Cheng J, Pandol S, Gukovskaya A: Caspases and poly(ADP-ribose) polymerase regulate the balance between apoptosis and necrosis in experimental pancreatitis. Gastroenterology 2003;124:A502.
-
(2003)
Gastroenterology
, vol.124
-
-
Gukovsky, I.1
Nam, K.2
Cheng, J.3
Pandol, S.4
Gukovskaya, A.5
-
96
-
-
0036086547
-
Caspase 8-mediated cleavage of plectin precedes F-actin breakdown in acinar cells during pancreatitis
-
Beil M, Leser J, Lutz MP, Gukovskaya A, Seufferlein T, Lynch G, Pandol SJ, Adler G: Caspase 8-mediated cleavage of plectin precedes F-actin breakdown in acinar cells during pancreatitis. Am J Physiol 2002;282:G450-G460.
-
(2002)
Am J Physiol
, vol.282
-
-
Beil, M.1
Leser, J.2
Lutz, M.P.3
Gukovskaya, A.4
Seufferlein, T.5
Lynch, G.6
Pandol, S.J.7
Adler, G.8
-
97
-
-
0033011746
-
Induction of permeability transition in pancreatic mitochondria by cerulein in rats
-
Schild L, Matthias R, Stanarius A, Wolf G, Augustin W, Halangk W: Induction of permeability transition in pancreatic mitochondria by cerulein in rats. Mol Cell Biochem 1999;195:191-197.
-
(1999)
Mol Cell Biochem
, vol.195
, pp. 191-197
-
-
Schild, L.1
Matthias, R.2
Stanarius, A.3
Wolf, G.4
Augustin, W.5
Halangk, W.6
-
98
-
-
0028966972
-
Intrapancreatic zymogen activation and levels of ATP and glutathione during caerulein pancreatitis in rats
-
Luthen R, Niederau C, Grendell JH: Intrapancreatic zymogen activation and levels of ATP and glutathione during caerulein pancreatitis in rats. Am J Physiol 1995;268:G592-G604.
-
(1995)
Am J Physiol
, vol.268
-
-
Luthen, R.1
Niederau, C.2
Grendell, J.H.3
-
99
-
-
0029059511
-
Energy metabolism in mouse pancreas in response to different dosages of a CCK analogue
-
Luthen RE, Niederau C, Ferrell LD, Grendell JH: Energy metabolism in mouse pancreas in response to different dosages of a CCK analogue. Pancreas 1995;11:141-146.
-
(1995)
Pancreas
, vol.11
, pp. 141-146
-
-
Luthen, R.E.1
Niederau, C.2
Ferrell, L.D.3
Grendell, J.H.4
-
100
-
-
11844292359
-
Inhibition of poly(ADPribose) polymerase attenuates the severity of caerulein-induced pancreatitis and associated lung injury by inhibition of NF-kB activation
-
Ku Y, Sharif R, Dhaulakhandi D, Dawra R, Bhagat L, Saluja A: Inhibition of poly(ADPribose) polymerase attenuates the severity of caerulein-induced pancreatitis and associated lung injury by inhibition of NF-kB activation. Pancreas 2003;27:392.
-
(2003)
Pancreas
, vol.27
, pp. 392
-
-
Ku, Y.1
Sharif, R.2
Dhaulakhandi, D.3
Dawra, R.4
Bhagat, L.5
Saluja, A.6
-
101
-
-
0033795691
-
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis
-
Halangk W, Lerch MM, Brandt-Nedelev B, Roth W, Ruthenbuerger M, Reinheckel T, Domschke W, Lippert H, Peters C, Deussing J: Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis. J Clin Invest 2000;106:773-781.
-
(2000)
J Clin Invest
, vol.106
, pp. 773-781
-
-
Halangk, W.1
Lerch, M.M.2
Brandt-Nedelev, B.3
Roth, W.4
Ruthenbuerger, M.5
Reinheckel, T.6
Domschke, W.7
Lippert, H.8
Peters, C.9
Deussing, J.10
-
102
-
-
0036720909
-
Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity
-
Van Acker GJ, Saluja AK, Bhagat L, Singh VP, Song AM, Steer ML: Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity. Am J Physiol 2002;283:G794-G800.
-
(2002)
Am J Physiol
, vol.283
-
-
Van Acker, G.J.1
Saluja, A.K.2
Bhagat, L.3
Singh, V.P.4
Song, A.M.5
Steer, M.L.6
-
103
-
-
0032246276
-
Early NF-κB activation is associated with hormone-induced pancreatitis
-
Gukovsky I, Gukovskaya AS, Blinman TA, Zaninovic V, Pandol SJ: Early NF-κB activation is associated with hormone-induced pancreatitis. Am J Physiol 1998;275:G1402-G1414.
-
(1998)
Am J Physiol
, vol.275
-
-
Gukovsky, I.1
Gukovskaya, A.S.2
Blinman, T.A.3
Zaninovic, V.4
Pandol, S.J.5
-
104
-
-
0032590082
-
NF-κB/Rel activation in cerulein pancreatitis
-
Steinle AU, Weidenbach H, Wagner M, Adler G, Schmid RM: NF-κB/Rel activation in cerulein pancreatitis. Gastroenterology 1999;116:420-430.
-
(1999)
Gastroenterology
, vol.116
, pp. 420-430
-
-
Steinle, A.U.1
Weidenbach, H.2
Wagner, M.3
Adler, G.4
Schmid, R.M.5
-
105
-
-
0034974849
-
Localized pancreatic NF-κB activation and inflammatory response in taurocholate-induced pancreatitis
-
Vaquero E, Gukovsky I, Zaninovic V, Gukovskaya AS, Pandol SJ: Localized pancreatic NF-κB activation and inflammatory response in taurocholate-induced pancreatitis. Am J Physiol 2001;280:G1197-G1208.
-
(2001)
Am J Physiol
, vol.280
-
-
Vaquero, E.1
Gukovsky, I.2
Zaninovic, V.3
Gukovskaya, A.S.4
Pandol, S.J.5
-
106
-
-
0036007501
-
NF-κB activation in pancreas induces pancreatic and systemic inflammatory response
-
Chen X, Ji B, Han B, Ernst SA, Simeone D, Logsdon CD: NF-κB activation in pancreas induces pancreatic and systemic inflammatory response. Gastroenterology 2002;122:448-457.
-
(2002)
Gastroenterology
, vol.122
, pp. 448-457
-
-
Chen, X.1
Ji, B.2
Han, B.3
Ernst, S.A.4
Simeone, D.5
Logsdon, C.D.6
-
107
-
-
0035179805
-
Phosphatidylinositol 3-kinase-dependent activation of trypsinogen modulates the severity of acute pancreatitis
-
Singh VP, Saluja AK, Bhagat L, van Acker GJ, Song AM, Soltoff SP, Cantley LC, Steer ML: Phosphatidylinositol 3-kinase-dependent activation of trypsinogen modulates the severity of acute pancreatitis. J Clin Invest 2001;108:1387-1395.
-
(2001)
J Clin Invest
, vol.108
, pp. 1387-1395
-
-
Singh, V.P.1
Saluja, A.K.2
Bhagat, L.3
Van Acker, G.J.4
Song, A.M.5
Soltoff, S.P.6
Cantley, L.C.7
Steer, M.L.8
-
108
-
-
0842321784
-
Phosphatidylinositide 3-kinase γ regulates key pathologic responses to cholecystokinin in pancreatic acinar cells
-
Gukovsky I, Cheng J, Nam K, Lee O, Lugea A, Fischer L, Penninger J, Pandol S, Gukovskaya A: Phosphatidylinositide 3-kinase γ regulates key pathologic responses to cholecystokinin in pancreatic acinar cells. Gastroenterology 2004;126:554-566.
-
(2004)
Gastroenterology
, vol.126
, pp. 554-566
-
-
Gukovsky, I.1
Cheng, J.2
Nam, K.3
Lee, O.4
Lugea, A.5
Fischer, L.6
Penninger, J.7
Pandol, S.8
Gukovskaya, A.9
-
109
-
-
0036135383
-
Both thermal and non-thermal stress protect against caerulein-induced pancreatitis and prevent trypsinogen activation in the pancreas
-
Frossard JL, Bhagat L, Lee HS, Hietaranta AJ, Singh VP, Song AM, Steer ML, Saluja AK: Both thermal and non-thermal stress protect against caerulein-induced pancreatitis and prevent trypsinogen activation in the pancreas. Gut 2002;50:78-83.
-
(2002)
Gut
, vol.50
, pp. 78-83
-
-
Frossard, J.L.1
Bhagat, L.2
Lee, H.S.3
Hietaranta, A.J.4
Singh, V.P.5
Song, A.M.6
Steer, M.L.7
Saluja, A.K.8
-
110
-
-
0033918085
-
Heat shock protein 70 prevents secretagogue-induced cell injury in the pancreas by preventing intracellular trypsinogen activation
-
Bhagat L, Singh VP, Hietaranta AJ, Agrawal S, Steer ML, Saluja AK: Heat shock protein 70 prevents secretagogue-induced cell injury in the pancreas by preventing intracellular trypsinogen activation. J Clin Invest 2000;106:81-89.
-
(2000)
J Clin Invest
, vol.106
, pp. 81-89
-
-
Bhagat, L.1
Singh, V.P.2
Hietaranta, A.J.3
Agrawal, S.4
Steer, M.L.5
Saluja, A.K.6
-
111
-
-
0036143683
-
Thermal stress-induced Hsp70 mediates protection against intrapancreatic trypsinogen activation and acute pancreatitis in rats
-
Bhagat L, Singh VP, Song AM, van Acker GJ, Agrawal S, Steer ML, Saluja AK: Thermal stress-induced Hsp70 mediates protection against intrapancreatic trypsinogen activation and acute pancreatitis in rats. Gastroenterology 2002;122:156-165.
-
(2002)
Gastroenterology
, vol.122
, pp. 156-165
-
-
Bhagat, L.1
Singh, V.P.2
Song, A.M.3
Van Acker, G.J.4
Agrawal, S.5
Steer, M.L.6
Saluja, A.K.7
-
112
-
-
0033984954
-
Stress kinases and heat shock proteins in the pancreas: Possible roles in normal function and disease
-
Schafer C, Williams JA: Stress kinases and heat shock proteins in the pancreas: Possible roles in normal function and disease. J Gastroenterol 2000;35:1-9.
-
(2000)
J Gastroenterol
, vol.35
, pp. 1-9
-
-
Schafer, C.1
Williams, J.A.2
-
113
-
-
0035374346
-
2+ changes
-
2+ changes. J Biol Chem 2001;276:18742-18747.
-
(2001)
J Biol Chem
, vol.276
, pp. 18742-18747
-
-
Hietaranta, A.J.1
Singh, V.P.2
Bhagat, L.3
Van Acker, G.J.4
Song, A.M.5
Mykoniatis, A.6
Steer, M.L.7
Saluja, A.K.8
-
115
-
-
0036797074
-
Suppression of cerulein-induced cytokine expression by antioxidants in pancreatic acinar cells
-
Yu JH, Lim JW, Namkung W, Kim H, Kim KH: Suppression of cerulein-induced cytokine expression by antioxidants in pancreatic acinar cells. Lab Invest 2002;82:1359-1368.
-
(2002)
Lab Invest
, vol.82
, pp. 1359-1368
-
-
Yu, J.H.1
Lim, J.W.2
Namkung, W.3
Kim, H.4
Kim, K.H.5
-
116
-
-
0032723773
-
Oxidative stress in acute pancreatitis
-
Schulz HU, Niederau C, Klonowski-Stumpe H, Halangk W, Luthen R, Lippert H: Oxidative stress in acute pancreatitis. Hepatogastroenterology 1999;46:2736-2750.
-
(1999)
Hepatogastroenterology
, vol.46
, pp. 2736-2750
-
-
Schulz, H.U.1
Niederau, C.2
Klonowski-Stumpe, H.3
Halangk, W.4
Luthen, R.5
Lippert, H.6
-
117
-
-
1342333658
-
Signal transduction, calcium and acute pancreatitis
-
Sutton R, Criddle D, Raraty MG, Tepikin A, Neoptolemos JP, Petersen OH: Signal transduction, calcium and acute pancreatitis. Pancreatology 2003;3:497-505.
-
(2003)
Pancreatology
, vol.3
, pp. 497-505
-
-
Sutton, R.1
Criddle, D.2
Raraty, M.G.3
Tepikin, A.4
Neoptolemos, J.P.5
Petersen, O.H.6
-
118
-
-
0036554826
-
Bile acids induce calcium signals in mouse pancreatic acinar cells: Implications for bile-induced pancreatic pathology
-
Voronina S, Longbottom R, Sutton R, Petersen OH, Tepikin A: Bile acids induce calcium signals in mouse pancreatic acinar cells: Implications for bile-induced pancreatic pathology. J Physiol 2002;540:49-55.
-
(2002)
J Physiol
, vol.540
, pp. 49-55
-
-
Voronina, S.1
Longbottom, R.2
Sutton, R.3
Petersen, O.H.4
Tepikin, A.5
-
119
-
-
0036402720
-
Calcium signal compartmentalization
-
Petersen OH: Calcium signal compartmentalization. Biol Res 2002;35:177-182.
-
(2002)
Biol Res
, vol.35
, pp. 177-182
-
-
Petersen, O.H.1
-
121
-
-
0038660678
-
Early changes in pancreatic acinar cell calcium signaling after pancreatic duct obstruction
-
Mooren FC, Hlouschek V, Finkes T, Turi S, Weber IA, Singh J, Domschke W, Schnekenburger J, Kruger B, Lerch MM: Early changes in pancreatic acinar cell calcium signaling after pancreatic duct obstruction. J Biol Chem 2003;278:9361-9369.
-
(2003)
J Biol Chem
, vol.278
, pp. 9361-9369
-
-
Mooren, F.C.1
Hlouschek, V.2
Finkes, T.3
Turi, S.4
Weber, I.A.5
Singh, J.6
Domschke, W.7
Schnekenburger, J.8
Kruger, B.9
Lerch, M.M.10
-
122
-
-
0029841658
-
The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis
-
Sandoval D, Gukovskaya A, Reavey P, Gukovsky S, Sisk A, Braquet P, Pandol SJ, Poucell-Hatton S: The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis. Gastroenterology 1996;111:1081-1091.
-
(1996)
Gastroenterology
, vol.111
, pp. 1081-1091
-
-
Sandoval, D.1
Gukovskaya, A.2
Reavey, P.3
Gukovsky, S.4
Sisk, A.5
Braquet, P.6
Pandol, S.J.7
Poucell-Hatton, S.8
-
123
-
-
0344605011
-
Role of transcription factor NF-kB in mediating hormone-induced pancreatitis
-
Gukovsky I, Blinman T, Zaninovic V, Jung Y, Gukovskaya A, Pandol S: Role of transcription factor NF-kB in mediating hormone-induced pancreatitis. Gastroenterology 1998;114:A465.
-
(1998)
Gastroenterology
, vol.114
-
-
Gukovsky, I.1
Blinman, T.2
Zaninovic, V.3
Jung, Y.4
Gukovskaya, A.5
Pandol, S.6
-
124
-
-
0033840023
-
Altered caspase expression results in delayed neutrophil apoptosis in acute pancreatitis
-
O'Neill S, O'Neill AJ, Conroy E, Brady HR, Fitzpatrick JM, Watson RW: Altered caspase expression results in delayed neutrophil apoptosis in acute pancreatitis. J Leukoc Biol 2000;68:15-20.
-
(2000)
J Leukoc Biol
, vol.68
, pp. 15-20
-
-
O'Neill, S.1
O'Neill, A.J.2
Conroy, E.3
Brady, H.R.4
Fitzpatrick, J.M.5
Watson, R.W.6
-
125
-
-
0036281903
-
Apoptosis in the peripheral blood mononuclear cells as a self-limitation process in human acute pancreatitis
-
Salomone T, Tosi P, Raiti C, Guariento A, Tomassetti P, Migliori M, Saieva C, Romboli M, Gullo L: Apoptosis in the peripheral blood mononuclear cells as a self-limitation process in human acute pancreatitis. Pancreatology 2002;2:204-210.
-
(2002)
Pancreatology
, vol.2
, pp. 204-210
-
-
Salomone, T.1
Tosi, P.2
Raiti, C.3
Guariento, A.4
Tomassetti, P.5
Migliori, M.6
Saieva, C.7
Romboli, M.8
Gullo, L.9
-
126
-
-
12444339743
-
Nuclear factorκB expression in peripheral blood mononuclear cells of patients with acute pancreatitis
-
Satoh A, Masamune A, Kimura K, Kaneko K, Sakai Y, Yamagiwa T, Satoh M, Kikuta K, Asakura T, Shimosegawa T: Nuclear factorκB expression in peripheral blood mononuclear cells of patients with acute pancreatitis. Pancreas 2003;26:350-356.
-
(2003)
Pancreas
, vol.26
, pp. 350-356
-
-
Satoh, A.1
Masamune, A.2
Kimura, K.3
Kaneko, K.4
Sakai, Y.5
Yamagiwa, T.6
Satoh, M.7
Kikuta, K.8
Asakura, T.9
Shimosegawa, T.10
-
127
-
-
0031843518
-
TNF but not IL-1 decreases pancreatic acinar cell survival without affecting exocrine function: A study in the perfused human pancreas
-
Denham W, Yang J, Fink G, Denham D, Carter G, Bowers V, Norman J: TNF but not IL-1 decreases pancreatic acinar cell survival without affecting exocrine function: A study in the perfused human pancreas. J Surg Res 1998;74:3-7.
-
(1998)
J Surg Res
, vol.74
, pp. 3-7
-
-
Denham, W.1
Yang, J.2
Fink, G.3
Denham, D.4
Carter, G.5
Bowers, V.6
Norman, J.7
-
128
-
-
0029971046
-
Induction of apoptosis reduces the severity of caerulein-induced pancreatitis in mice
-
Saluja A, Hofbauer B, Yamaguchi Y, Yamanaka K, Steer M: Induction of apoptosis reduces the severity of caerulein-induced pancreatitis in mice. Biochem Biophys Res Commun 1996;220:875-878.
-
(1996)
Biochem Biophys Res Commun
, vol.220
, pp. 875-878
-
-
Saluja, A.1
Hofbauer, B.2
Yamaguchi, Y.3
Yamanaka, K.4
Steer, M.5
-
129
-
-
0032546484
-
Induction of apoptosis in pancreatic acinar cells reduces the severity of acute pancreatitis
-
Bhatia M, Wallig MA, Hofbauer B, Lee HS, Frossard JL, Steer ML, Saluja AK: Induction of apoptosis in pancreatic acinar cells reduces the severity of acute pancreatitis. Biochem Biophys Res Commun 1998;246:476-483.
-
(1998)
Biochem Biophys Res Commun
, vol.246
, pp. 476-483
-
-
Bhatia, M.1
Wallig, M.A.2
Hofbauer, B.3
Lee, H.S.4
Frossard, J.L.5
Steer, M.L.6
Saluja, A.K.7
-
130
-
-
0029836691
-
Effects of cycloheximide on pancreatic endonuclease activity, apoptosis, and severity of acute pancreatitis
-
Kaiser AM, Saluja AK, Lu L, Yamanaka K, Yamaguchi Y, Steer ML: Effects of cycloheximide on pancreatic endonuclease activity, apoptosis, and severity of acute pancreatitis. Am J Physiol 1996;271:C982-C993.
-
(1996)
Am J Physiol
, vol.271
-
-
Kaiser, A.M.1
Saluja, A.K.2
Lu, L.3
Yamanaka, K.4
Yamaguchi, Y.5
Steer, M.L.6
-
131
-
-
0007631596
-
-
Totowa, Humana Press
-
Reber H: Pancreatic Cancer, Pathogenesis, Diagnosis, and Treatment. Totowa, Humana Press, 1998.
-
(1998)
Pancreatic Cancer, Pathogenesis, Diagnosis, and Treatment
-
-
Reber, H.1
-
132
-
-
0035177036
-
Growth factors and their receptors in pancreatic cancer
-
Ozawa F, Friess H, Tempia-Caliera A, Kleeff J, Buchler MW: Growth factors and their receptors in pancreatic cancer. Teratog Carcinog Mutagen 2001;21:27-44.
-
(2001)
Teratog Carcinog Mutagen
, vol.21
, pp. 27-44
-
-
Ozawa, F.1
Friess, H.2
Tempia-Caliera, A.3
Kleeff, J.4
Buchler, M.W.5
-
133
-
-
0027131252
-
Enhanced expression of transforming growth factor β isoforms in pancreatic cancer correlates with decreased survival
-
Friess H, Yamanaka Y, Buchler M, Ebert M, Beger HG, Gold LI, Korc M: Enhanced expression of transforming growth factor β isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology 1993;105:1846-1856.
-
(1993)
Gastroenterology
, vol.105
, pp. 1846-1856
-
-
Friess, H.1
Yamanaka, Y.2
Buchler, M.3
Ebert, M.4
Beger, H.G.5
Gold, L.I.6
Korc, M.7
-
134
-
-
0027435936
-
Overexpression of acidic and basic fibroblast growth factors in human pancreatic cancer correlates with advanced tumor stage
-
Yamanaka Y, Friess H, Buchler M, Beger HG, Uchida E, Onda M, Kobrin MS, Korc M: Overexpression of acidic and basic fibroblast growth factors in human pancreatic cancer correlates with advanced tumor stage. Cancer Res 1993;53:5289-5296.
-
(1993)
Cancer Res
, vol.53
, pp. 5289-5296
-
-
Yamanaka, Y.1
Friess, H.2
Buchler, M.3
Beger, H.G.4
Uchida, E.5
Onda, M.6
Kobrin, M.S.7
Korc, M.8
-
135
-
-
0031934765
-
Role of growth factors in pancreatic cancer
-
Korc M: Role of growth factors in pancreatic cancer. Surg Oncol Clin N Am 1998;7:25-41.
-
(1998)
Surg Oncol Clin N Am
, vol.7
, pp. 25-41
-
-
Korc, M.1
-
136
-
-
0141988681
-
Genetic blockade of the insulin-like growth factor-1 receptor: A promising strategy for human pancreatic cancer
-
Min Y, Adachi Y, Yamamoto H, Ito H, Itoh F, Lee CT, Nadaf S, Carbone DP, Imai K: Genetic blockade of the insulin-like growth factor-1 receptor: A promising strategy for human pancreatic cancer. Cancer Res 2003;63:6432-6441.
-
(2003)
Cancer Res
, vol.63
, pp. 6432-6441
-
-
Min, Y.1
Adachi, Y.2
Yamamoto, H.3
Ito, H.4
Itoh, F.5
Lee, C.T.6
Nadaf, S.7
Carbone, D.P.8
Imai, K.9
-
137
-
-
0035341742
-
Acidic fibroblast growth factor (FGF-1) signaling inhibits peroxynitriteinduced cell death during pancreatic tumorigenesis
-
Vickers SM, MacMillan-Crow L, Huang Z, Thompson JA: Acidic fibroblast growth factor (FGF-1) signaling inhibits peroxynitriteinduced cell death during pancreatic tumorigenesis. Free Radic Biol Med 2001;30:957-966.
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 957-966
-
-
Vickers, S.M.1
MacMillan-Crow, L.2
Huang, Z.3
Thompson, J.A.4
-
138
-
-
0036186862
-
Myofibroblasts are responsible for the desmoplastic reaction surrounding human pancreatic carcinomas
-
Yen TW, Aardal NP, Bronner MP, Thorning DR, Savard CE, Lee SP, Bell RH Jr: Myofibroblasts are responsible for the desmoplastic reaction surrounding human pancreatic carcinomas. Surgery 2002;131:129-134.
-
(2002)
Surgery
, vol.131
, pp. 129-134
-
-
Yen, T.W.1
Aardal, N.P.2
Bronner, M.P.3
Thorning, D.R.4
Savard, C.E.5
Lee, S.P.6
Bell Jr., R.H.7
-
139
-
-
0028157921
-
Human ductal adenocarcinomas of the pancreas express extracellular matrix proteins
-
Lohr M, Trautmann B, Gottler M, Peters S, Zauner I, Maillet B, Kloppel G: Human ductal adenocarcinomas of the pancreas express extracellular matrix proteins. Br J Cancer 1994;69:144-151.
-
(1994)
Br J Cancer
, vol.69
, pp. 144-151
-
-
Lohr, M.1
Trautmann, B.2
Gottler, M.3
Peters, S.4
Zauner, I.5
Maillet, B.6
Kloppel, G.7
-
140
-
-
0029940924
-
Expression and function of receptors for extracellular matrix proteins in human ductal adenocarcinomas of the pancreas
-
Lohr M, Trautmann B, Gottler M, Peters S, Zauner I, Maier A, Kloppel G, Liebe S, Kreuser ED: Expression and function of receptors for extracellular matrix proteins in human ductal adenocarcinomas of the pancreas. Pancreas 1996;12:248-259.
-
(1996)
Pancreas
, vol.12
, pp. 248-259
-
-
Lohr, M.1
Trautmann, B.2
Gottler, M.3
Peters, S.4
Zauner, I.5
Maier, A.6
Kloppel, G.7
Liebe, S.8
Kreuser, E.D.9
-
141
-
-
0141706392
-
Extracellular matrix proteins protect pancreatic cancer cells from death via mitochondrial and nonmitochondrial pathways
-
Vaquero EC, Edderkaoui M, Nam KJ, Gukovsky I, Pandol SJ, Gukovskaya AS: Extracellular matrix proteins protect pancreatic cancer cells from death via mitochondrial and nonmitochondrial pathways. Gastroenterology 2003;125:1188-1202.
-
(2003)
Gastroenterology
, vol.125
, pp. 1188-1202
-
-
Vaquero, E.C.1
Edderkaoui, M.2
Nam, K.J.3
Gukovsky, I.4
Pandol, S.J.5
Gukovskaya, A.S.6
-
142
-
-
4544250814
-
Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells
-
Vaquero E, Edderkaoui M, Gukovsky I, Pandol S, Gukovskaya A: Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells. J Biol Chem 2004;279:34643-34654.
-
(2004)
J Biol Chem
, vol.279
, pp. 34643-34654
-
-
Vaquero, E.1
Edderkaoui, M.2
Gukovsky, I.3
Pandol, S.4
Gukovskaya, A.5
-
143
-
-
11844289959
-
Extracellular matrix proteins stimulate reactive oxygen species production in human pancreatic cancer cells through non-mitochondrial NAD(P)H oxidase
-
Edderkaoui M, Vaquero E, Pandol S, Gukovskaya A: Extracellular matrix proteins stimulate reactive oxygen species production in human pancreatic cancer cells through non-mitochondrial NAD(P)H oxidase. Pancreas 2003;27:379.
-
(2003)
Pancreas
, vol.27
, pp. 379
-
-
Edderkaoui, M.1
Vaquero, E.2
Pandol, S.3
Gukovskaya, A.4
-
144
-
-
11844254188
-
Non-mitochondrial NAD(P)H oxidase mediates growth factorinduced ROS production and suppression of apoptosis in pancreatic cancer cells
-
Vaquero E, Nam K, Gukovsky I, Pandol S, Gukovskaya A: Non-mitochondrial NAD(P)H oxidase mediates growth factorinduced ROS production and suppression of apoptosis in pancreatic cancer cells. Gastroenterology 2003;124:A290.
-
(2003)
Gastroenterology
, vol.124
-
-
Vaquero, E.1
Nam, K.2
Gukovsky, I.3
Pandol, S.4
Gukovskaya, A.5
-
145
-
-
0034012799
-
Fas and Fas-ligand expression in human pancreatic cancer
-
Kornmann M, Ishiwata T, Kleeff J, Beger HG, Korc M: Fas and Fas-ligand expression in human pancreatic cancer. Ann Surg 2000;231:368-379.
-
(2000)
Ann Surg
, vol.231
, pp. 368-379
-
-
Kornmann, M.1
Ishiwata, T.2
Kleeff, J.3
Beger, H.G.4
Korc, M.5
-
146
-
-
0034956807
-
Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death
-
Ibrahim SM, Ringel J, Schmidt C, Ringel B, Muller P, Koczan D, Thiesen HJ, Lohr M: Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death. Pancreas 2001;23:72-79.
-
(2001)
Pancreas
, vol.23
, pp. 72-79
-
-
Ibrahim, S.M.1
Ringel, J.2
Schmidt, C.3
Ringel, B.4
Muller, P.5
Koczan, D.6
Thiesen, H.J.7
Lohr, M.8
-
147
-
-
0036672868
-
Selective targeting of the nuclear factor-κB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death
-
Thomas RP, Farrow BJ, Kim S, May MJ, Hellmich MR, Evers BM: Selective targeting of the nuclear factor-κB pathway enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated pancreatic cancer cell death. Surgery 2002;132:127-134.
-
(2002)
Surgery
, vol.132
, pp. 127-134
-
-
Thomas, R.P.1
Farrow, B.J.2
Kim, S.3
May, M.J.4
Hellmich, M.R.5
Evers, B.M.6
-
148
-
-
17944379442
-
CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-κB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells
-
Trauzold A, Wermann H, Arlt A, Schutze S, Schafer H, Oestern S, Roder C, Ungefroren H, Lampe E, Heinrich M, Walczak H, Kalthoff H: CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-κB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells. Oncogene 2001;20:4258-4269.
-
(2001)
Oncogene
, vol.20
, pp. 4258-4269
-
-
Trauzold, A.1
Wermann, H.2
Arlt, A.3
Schutze, S.4
Schafer, H.5
Oestern, S.6
Roder, C.7
Ungefroren, H.8
Lampe, E.9
Heinrich, M.10
Walczak, H.11
Kalthoff, H.12
-
149
-
-
0036134173
-
Molecular mechanism(s) of actinomycin-D induced sensitization of pancreatic cancer cells to CD95 mediated apoptosis
-
Glazyrin AL, Chinni S, Alhasan S, Adsay VN, Vaitkevicius VK, Sarkar FH: Molecular mechanism(s) of actinomycin-D induced sensitization of pancreatic cancer cells to CD95 mediated apoptosis. Int J Oncol 2002;20:201-205.
-
(2002)
Int J Oncol
, vol.20
, pp. 201-205
-
-
Glazyrin, A.L.1
Chinni, S.2
Alhasan, S.3
Adsay, V.N.4
Vaitkevicius, V.K.5
Sarkar, F.H.6
-
150
-
-
0038545700
-
Endogenous decoy receptor 3 blocks the growth inhibition signals mediated by Fas ligand in human pancreatic adenocarcinoma
-
Tsuji S, Hosotani R, Yonehara S, Masui T, Tulachan SS, Nakajima S, Kobayashi H, Koizumi M, Toyoda E, Ito D, Kami K, Mori T, Fujimoto K, Doi R, Imamura M: Endogenous decoy receptor 3 blocks the growth inhibition signals mediated by Fas ligand in human pancreatic adenocarcinoma. Int J Cancer 2003;106:17-25.
-
(2003)
Int J Cancer
, vol.106
, pp. 17-25
-
-
Tsuji, S.1
Hosotani, R.2
Yonehara, S.3
Masui, T.4
Tulachan, S.S.5
Nakajima, S.6
Kobayashi, H.7
Koizumi, M.8
Toyoda, E.9
Ito, D.10
Kami, K.11
Mori, T.12
Fujimoto, K.13
Doi, R.14
Imamura, M.15
-
151
-
-
0037128667
-
Analysis of the cytochrome c-dependent apoptosis apparatus in cells from human pancreatic carcinoma
-
Gerhard MC, Schmid RM, Hacker G: Analysis of the cytochrome c-dependent apoptosis apparatus in cells from human pancreatic carcinoma. Br J Cancer 2002;86:893-898.
-
(2002)
Br J Cancer
, vol.86
, pp. 893-898
-
-
Gerhard, M.C.1
Schmid, R.M.2
Hacker, G.3
-
152
-
-
0035823503
-
Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity
-
Wolf BB, Schuler M, Li W, Eggers-Sedlet B, Lee W, Tailor P, Fitzgerald P, Mills GB, Green DR: Defective cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity. J Biol Chem 2001;276:34244-34251.
-
(2001)
J Biol Chem
, vol.276
, pp. 34244-34251
-
-
Wolf, B.B.1
Schuler, M.2
Li, W.3
Eggers-Sedlet, B.4
Lee, W.5
Tailor, P.6
Fitzgerald, P.7
Mills, G.B.8
Green, D.R.9
-
153
-
-
0031715838
-
Bax, but not bcl-2, influences the prognosis of human pancreatic cancer
-
Friess H, Lu Z, Graber HU, Zimmermann A, Adler G, Korc M, Schmid RM, Buchler MW: Bax, but not bcl-2, influences the prognosis of human pancreatic cancer. Gut 1998;43:414-421.
-
(1998)
Gut
, vol.43
, pp. 414-421
-
-
Friess, H.1
Lu, Z.2
Graber, H.U.3
Zimmermann, A.4
Adler, G.5
Korc, M.6
Schmid, R.M.7
Buchler, M.W.8
-
154
-
-
0032600214
-
Bak expression and cell death occur in peritumorous tissue but not in pancreatic cancer cells
-
Graber HU, Friess H, Zimmermann A, Korc M, Adler G, Schmid R, Buchler MW: Bak expression and cell death occur in peritumorous tissue but not in pancreatic cancer cells. J Gastrointest Surg 1999;3:74-80.
-
(1999)
J Gastrointest Surg
, vol.3
, pp. 74-80
-
-
Graber, H.U.1
Friess, H.2
Zimmermann, A.3
Korc, M.4
Adler, G.5
Schmid, R.6
Buchler, M.W.7
-
155
-
-
0344440978
-
Multiple and synergistic deregulations of apoptosis-controlling genes in pancreatic carcinoma cells
-
Trauzold A, Schmiedel S, Roder C, Tams C, Christgen M, Oestern S, Arlt A, Westphal S, Kapischke M, Ungefroren H, Kalthoff H: Multiple and synergistic deregulations of apoptosis-controlling genes in pancreatic carcinoma cells. Br J Cancer 2003;89:1714-1721.
-
(2003)
Br J Cancer
, vol.89
, pp. 1714-1721
-
-
Trauzold, A.1
Schmiedel, S.2
Roder, C.3
Tams, C.4
Christgen, M.5
Oestern, S.6
Arlt, A.7
Westphal, S.8
Kapischke, M.9
Ungefroren, H.10
Kalthoff, H.11
-
156
-
-
0033741010
-
Bcl-2/Bax protein ratio predicts 5-fluorouracil sensitivity independently of p53 status
-
Mirjolet JF, Barberi-Heyob M, Didelot C, Peyrat JP, Abecassis J, Millon R, Merlin JL: Bcl-2/Bax protein ratio predicts 5-fluorouracil sensitivity independently of p53 status. Br J Cancer 2000;83:1380-1386.
-
(2000)
Br J Cancer
, vol.83
, pp. 1380-1386
-
-
Mirjolet, J.F.1
Barberi-Heyob, M.2
Didelot, C.3
Peyrat, J.P.4
Abecassis, J.5
Millon, R.6
Merlin, J.L.7
-
157
-
-
0035447423
-
Bcl-2 expression correlates with metastatic potential in pancreatic cancer cell lines
-
Bold RJ, Virudachalam S, McConkey DJ: Bcl-2 expression correlates with metastatic potential in pancreatic cancer cell lines. Cancer 2001;92:1122-1129.
-
(2001)
Cancer
, vol.92
, pp. 1122-1129
-
-
Bold, R.J.1
Virudachalam, S.2
McConkey, D.J.3
-
158
-
-
0032943591
-
The nuclear factor-κB/RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells
-
Wang W, Abbruzzese JL, Evans DB, Larry L, Cleary KR, Chiao PJ: The nuclear factor-κB/RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Clin Cancer Res 1999;5:119-127.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 119-127
-
-
Wang, W.1
Abbruzzese, J.L.2
Evans, D.B.3
Larry, L.4
Cleary, K.R.5
Chiao, P.J.6
-
159
-
-
0036884187
-
Stat3 and NF-κB activation prevents apoptosis in pancreatic carcinogenesis
-
Greten FR, Weber CK, Greten TF, Schneider G, Wagner M, Adler G, Schmid RM: Stat3 and NF-κB activation prevents apoptosis in pancreatic carcinogenesis. Gastroenterology 2002;123:2052-2063.
-
(2002)
Gastroenterology
, vol.123
, pp. 2052-2063
-
-
Greten, F.R.1
Weber, C.K.2
Greten, T.F.3
Schneider, G.4
Wagner, M.5
Adler, G.6
Schmid, R.M.7
-
160
-
-
0037780982
-
Mitogenic and antiapoptotic role of constitutive NF-κB/Rel activity in pancreatic cancer
-
Liptay S, Weber CK, Ludwig L, Wagner M, Adler G, Schmid RM: Mitogenic and antiapoptotic role of constitutive NF-κB/Rel activity in pancreatic cancer. Int J Cancer 2003;105:735-746.
-
(2003)
Int J Cancer
, vol.105
, pp. 735-746
-
-
Liptay, S.1
Weber, C.K.2
Ludwig, L.3
Wagner, M.4
Adler, G.5
Schmid, R.M.6
-
161
-
-
0037422205
-
Inhibition of constitutive NF-κB activity by IκBa M suppresses tumorigenesis
-
Fujioka S, Sclabas GM, Schmidt C, Niu J, Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C, Chiao PJ: Inhibition of constitutive NF-κB activity by IκBa M suppresses tumorigenesis. Oncogene 2003;22:1365-1370.
-
(2003)
Oncogene
, vol.22
, pp. 1365-1370
-
-
Fujioka, S.1
Sclabas, G.M.2
Schmidt, C.3
Niu, J.4
Frederick, W.A.5
Dong, Q.G.6
Abbruzzese, J.L.7
Evans, D.B.8
Baker, C.9
Chiao, P.J.10
-
162
-
-
0034981649
-
26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer
-
Shah SA, Potter MW, McDade TP, Ricciardi R, Perugini RA, Elliott PJ, Adams J, Callery MP: 26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer. J Cell Biochem 2001;82:110-122.
-
(2001)
J Cell Biochem
, vol.82
, pp. 110-122
-
-
Shah, S.A.1
Potter, M.W.2
McDade, T.P.3
Ricciardi, R.4
Perugini, R.A.5
Elliott, P.J.6
Adams, J.7
Callery, M.P.8
-
163
-
-
0012433771
-
Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts
-
Nawrocki ST, Bruns CJ, Harbison MT, Bold RJ, Gotsch BS, Abbruzzese JL, Elliott P, Adams J, McConkey DJ: Effects of the proteasome inhibitor PS-341 on apoptosis and angiogenesis in orthotopic human pancreatic tumor xenografts. Mol Cancer Ther 2002;1:1243-1253.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 1243-1253
-
-
Nawrocki, S.T.1
Bruns, C.J.2
Harbison, M.T.3
Bold, R.J.4
Gotsch, B.S.5
Abbruzzese, J.L.6
Elliott, P.7
Adams, J.8
McConkey, D.J.9
-
164
-
-
0038324141
-
Leucine-zipper protein, LDOC1, inhibits NF-κB activation and sensitizes pancreatic cancer cells to apoptosis
-
Nagasaki K, Schem C, von Kaisenberg C, Biallek M, Rosel F, Jonat W, Maass N: Leucine-zipper protein, LDOC1, inhibits NF-κB activation and sensitizes pancreatic cancer cells to apoptosis. Int J Cancer 2003;105:454-458.
-
(2003)
Int J Cancer
, vol.105
, pp. 454-458
-
-
Nagasaki, K.1
Schem, C.2
Von Kaisenberg, C.3
Biallek, M.4
Rosel, F.5
Jonat, W.6
Maass, N.7
-
165
-
-
0041338049
-
Inhibition of the phosphatidylinositol 3-kinase-AKT pathway induces apoptosis in pancreatic carcinoma cells in vitro and in vivo
-
Bondar VM, Sweeney-Gotsch B, Andreeff M, Mills GB, McConkey DJ: Inhibition of the phosphatidylinositol 3)-kinase-AKT pathway induces apoptosis in pancreatic carcinoma cells in vitro and in vivo. Mol Cancer Ther 2002;1:989-997.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 989-997
-
-
Bondar, V.M.1
Sweeney-Gotsch, B.2
Andreeff, M.3
Mills, G.B.4
McConkey, D.J.5
-
166
-
-
0036949812
-
Differential mechanisms of constitutive Akt/PKB activation and its influence on gene expression in pancreatic cancer cells
-
Matsumoto J, Kaneda M, Tada M, Hamada J, Okushiba S, Kondo S, Katoh H, Moriuchi T: Differential mechanisms of constitutive Akt/PKB activation and its influence on gene expression in pancreatic cancer cells. Jpn J Cancer Res 2002;93:1317-1326.
-
(2002)
Jpn J Cancer Res
, vol.93
, pp. 1317-1326
-
-
Matsumoto, J.1
Kaneda, M.2
Tada, M.3
Hamada, J.4
Okushiba, S.5
Kondo, S.6
Katoh, H.7
Moriuchi, T.8
-
167
-
-
0038621384
-
Role of NF-κB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death
-
Arlt A, Gehrz A, Muerkoster S, Vorndamm J, Kruse ML, Folsch UR, Schafer H: Role of NF-κB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death. Oncogene 2003;22:3243-3251.
-
(2003)
Oncogene
, vol.22
, pp. 3243-3251
-
-
Arlt, A.1
Gehrz, A.2
Muerkoster, S.3
Vorndamm, J.4
Kruse, M.L.5
Folsch, U.R.6
Schafer, H.7
-
168
-
-
0043122940
-
AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2
-
Fahy BN, Schlieman M, Virudachalam S, Bold RJ: AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2. Br J Cancer 2003;89:391-397.
-
(2003)
Br J Cancer
, vol.89
, pp. 391-397
-
-
Fahy, B.N.1
Schlieman, M.2
Virudachalam, S.3
Bold, R.J.4
-
169
-
-
0042807689
-
Growth-inhibitory effect of phosphatidylinositol 3-kinase inhibitor on human pancreatic cancer cells and expression of Bcl-2 family
-
Katayose K, Seki T, Ohba N, Funatomi H, Goto N, Mitamura K: Growth-inhibitory effect of phosphatidylinositol 3-kinase inhibitor on human pancreatic cancer cells and expression of Bcl-2 family. Anticancer Res 2003;23:2383-2387.
-
(2003)
Anticancer Res
, vol.23
, pp. 2383-2387
-
-
Katayose, K.1
Seki, T.2
Ohba, N.3
Funatomi, H.4
Goto, N.5
Mitamura, K.6
-
170
-
-
0024292722
-
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
-
Almoguera C, Shibata D, Forrester K, Martin J, Arnheim N, Perucho M: Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell 1988;53:549-554.
-
(1988)
Cell
, vol.53
, pp. 549-554
-
-
Almoguera, C.1
Shibata, D.2
Forrester, K.3
Martin, J.4
Arnheim, N.5
Perucho, M.6
-
172
-
-
0033624988
-
Adenovirus-mediated anti-K-ras ribozyme induces apoptosis and growth suppression of human pancreatic carcinoma
-
Tsuchida T, Kijima H, Hori S, Oshika Y, Tokunaga T, Kawai K, Yamazaki H, Ueyama Y, Scanlon KJ, Tamaoki N, Nakamura M: Adenovirus-mediated anti-K-ras ribozyme induces apoptosis and growth suppression of human pancreatic carcinoma. Cancer Gene Ther 2000;7:373-383.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 373-383
-
-
Tsuchida, T.1
Kijima, H.2
Hori, S.3
Oshika, Y.4
Tokunaga, T.5
Kawai, K.6
Yamazaki, H.7
Ueyama, Y.8
Scanlon, K.J.9
Tamaoki, N.10
Nakamura, M.11
-
173
-
-
0036728051
-
Lipoxygenase inhibitors attenuate growth of human pancreatic cancer xenografts and induce apoptosis through the mitochondrial pathway
-
Tong WG, Ding XZ, Witt RC, Adrian TE: Lipoxygenase inhibitors attenuate growth of human pancreatic cancer xenografts and induce apoptosis through the mitochondrial pathway. Mol Cancer Ther 2002;1:929-935.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 929-935
-
-
Tong, W.G.1
Ding, X.Z.2
Witt, R.C.3
Adrian, T.E.4
-
174
-
-
1342315146
-
Lipoxygenase and cyclooxygenase metabolism: New insights in treatment and chemoprevention of pancreatic cancer
-
Ding XZ, Hennig R, Adrian TE: Lipoxygenase and cyclooxygenase metabolism: New insights in treatment and chemoprevention of pancreatic cancer. Mol Cancer 2003;2:10.
-
(2003)
Mol Cancer
, vol.2
, pp. 10
-
-
Ding, X.Z.1
Hennig, R.2
Adrian, T.E.3
-
175
-
-
0035545994
-
12-Lipoxygenase metabolite 12(S)-HETE stimulates human pancreatic cancer cell proliferation via protein tyrosine phosphorylation and ERK activation
-
Ding XZ, Tong WG, Adrian TE: 12-Lipoxygenase metabolite 12(S)-HETE stimulates human pancreatic cancer cell proliferation via protein tyrosine phosphorylation and ERK activation. Int J Cancer 2001;94:630-636.
-
(2001)
Int J Cancer
, vol.94
, pp. 630-636
-
-
Ding, X.Z.1
Tong, W.G.2
Adrian, T.E.3
-
176
-
-
0033590192
-
Lipoxygenase inhibition induced apoptosis, morphological changes, and carbonic anhydrase expression in human pancreatic cancer cells
-
Ding XZ, Kuszynski CA, El Metwally TH, Adrian TE: Lipoxygenase inhibition induced apoptosis, morphological changes, and carbonic anhydrase expression in human pancreatic cancer cells. Biochem Biophys Res Commun 1999;266:392-399.
-
(1999)
Biochem Biophys Res Commun
, vol.266
, pp. 392-399
-
-
Ding, X.Z.1
Kuszynski, C.A.2
El Metwally, T.H.3
Adrian, T.E.4
-
177
-
-
0035458615
-
Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions
-
Avis I, Hong SH, Martinez A, Moody T, Choidy T, Choi YH, Trepel J, Das R, Jett M, Mulshine JL: Five-lipoxygenase inhibitors can mediate apoptosis in human breast cancer cell lines through complex eicosanoid interactions. FASEB J 2001;15:2007-2009.
-
(2001)
FASEB J
, vol.15
, pp. 2007-2009
-
-
Avis, I.1
Hong, S.H.2
Martinez, A.3
Moody, T.4
Choidy, T.5
Choi, Y.H.6
Trepel, J.7
Das, R.8
Jett, M.9
Mulshine, J.L.10
-
178
-
-
0038013796
-
Inhibition of arachidonate 5-lipoxygenase triggers prostate cancer cell death through rapid activation of c-Jun N-terminal kinase
-
Ghosh J: Inhibition of arachidonate 5-lipoxygenase triggers prostate cancer cell death through rapid activation of c-Jun N-terminal kinase. Biochem Biophys Res Commun 2003;307:342-349.
-
(2003)
Biochem Biophys Res Commun
, vol.307
, pp. 342-349
-
-
Ghosh, J.1
-
179
-
-
0034624064
-
Eicosanoid activation of extracellular signalregulated kinase1/2 in human epidermoid carcinoma cells
-
Szekeres CK, Tang K, Trikha M, Honn KV: Eicosanoid activation of extracellular signalregulated kinase1/2 in human epidermoid carcinoma cells. J Biol Chem 2000;275:38831-38841.
-
(2000)
J Biol Chem
, vol.275
, pp. 38831-38841
-
-
Szekeres, C.K.1
Tang, K.2
Trikha, M.3
Honn, K.V.4
-
180
-
-
0033990344
-
Cell type-specific role for reactive oxygen species in nuclear factor-κB activation by interleukin-1
-
Bonizzi G, Piette J, Merville MP, Bours V: Cell type-specific role for reactive oxygen species in nuclear factor-κB activation by interleukin-1. Biochem Pharmacol 2000;59:7-11.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 7-11
-
-
Bonizzi, G.1
Piette, J.2
Merville, M.P.3
Bours, V.4
-
181
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden KH, Lu X: Live or let die: The cell's response to p53. Nat Rev Cancer 2002;2:594-604.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
182
-
-
0034683576
-
1 fibronectin receptor
-
1 fibronectin receptor. J Cell Biol 2000;150:1467-1478.
-
(2000)
J Cell Biol
, vol.150
, pp. 1467-1478
-
-
Plath, T.1
Detjen, K.2
Welzel, M.3
Von Marschall, Z.4
Murphy, D.5
Schirner, M.6
Wiedenmann, B.7
Rosewicz, S.8
-
183
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernandez-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M: Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 2003;425:851-856.
-
(2003)
Nature
, vol.425
, pp. 851-856
-
-
Thayer, S.P.1
Di Magliano, M.P.2
Heiser, P.W.3
Nielsen, C.M.4
Roberts, D.J.5
Lauwers, G.Y.6
Qi, Y.P.7
Gysin, S.8
Fernandez-del Castillo, C.9
Yajnik, V.10
Antoniu, B.11
McMahon, M.12
Warshaw, A.L.13
Hebrok, M.14
-
184
-
-
0033032317
-
Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo
-
Sethi T, Rintoul RC, Moore SM, MacKinnon AC, Salter D, Choo C, Chilvers ER, Dransfield I, Donnelly SC, Strieter R, Haslett C: Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo. Nat Med 1999;5:662-668.
-
(1999)
Nat Med
, vol.5
, pp. 662-668
-
-
Sethi, T.1
Rintoul, R.C.2
Moore, S.M.3
MacKinnon, A.C.4
Salter, D.5
Choo, C.6
Chilvers, E.R.7
Dransfield, I.8
Donnelly, S.C.9
Strieter, R.10
Haslett, C.11
-
185
-
-
0034618369
-
MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells
-
Boucher MJ, Morisset J, Vachon PH, Reed JC, Laine J, Rivard N: MEK/ERK signaling pathway regulates the expression of Bcl-2, Bcl-X(L), and Mcl-1 and promotes survival of human pancreatic cancer cells. J Cell Biochem 2000;79:355-369.
-
(2000)
J Cell Biochem
, vol.79
, pp. 355-369
-
-
Boucher, M.J.1
Morisset, J.2
Vachon, P.H.3
Reed, J.C.4
Laine, J.5
Rivard, N.6
-
186
-
-
0037051715
-
Foodderived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome C release and apoptosis
-
Mouria M, Gukovskaya AS, Jung Y, Buechler P, Hines OJ, Reber HA, Pandol SJ: Foodderived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome C release and apoptosis. Int J Cancer 2002;98:761-769.
-
(2002)
Int J Cancer
, vol.98
, pp. 761-769
-
-
Mouria, M.1
Gukovskaya, A.S.2
Jung, Y.3
Buechler, P.4
Hines, O.J.5
Reber, H.A.6
Pandol, S.J.7
-
187
-
-
12244306910
-
Prevention of metastatic pancreatic cancer growth in vivo by induction of apoptosis with genistein, a naturally occurring isoflavonoid
-
Buchler P, Gukovskaya AS, Mouria M, Buchler MC, Buchler MW, Friess H, Pandol SJ, Reber HA, Hines OJ: Prevention of metastatic pancreatic cancer growth in vivo by induction of apoptosis with genistein, a naturally occurring isoflavonoid. Pancreas 2003;26:264-273.
-
(2003)
Pancreas
, vol.26
, pp. 264-273
-
-
Buchler, P.1
Gukovskaya, A.S.2
Mouria, M.3
Buchler, M.C.4
Buchler, M.W.5
Friess, H.6
Pandol, S.J.7
Reber, H.A.8
Hines, O.J.9
-
188
-
-
0035888180
-
Bcl-x(L) antisense oligonucleotides induce apoptosis and increase sensitivity of pancreatic cancer cells to gemcitabine
-
Xu Z, Friess H, Solioz M, Aebi S, Korc M, Kleeff J, Buchler MW: Bcl-x(L) antisense oligonucleotides induce apoptosis and increase sensitivity of pancreatic cancer cells to gemcitabine. Int J Cancer 2001;94:268-274.
-
(2001)
Int J Cancer
, vol.94
, pp. 268-274
-
-
Xu, Z.1
Friess, H.2
Solioz, M.3
Aebi, S.4
Korc, M.5
Kleeff, J.6
Buchler, M.W.7
-
189
-
-
0037743875
-
Chemosensitivity of human pancreatic carcinoma cells is enhanced by IκBa super-repressor
-
Sato T, Odagiri H, Ikenaga SK, Maruyama M, Sasaki M: Chemosensitivity of human pancreatic carcinoma cells is enhanced by IκBa super-repressor. Cancer Sci 2003;94:467-472.
-
(2003)
Cancer Sci
, vol.94
, pp. 467-472
-
-
Sato, T.1
Odagiri, H.2
Ikenaga, S.K.3
Maruyama, M.4
Sasaki, M.5
-
190
-
-
0033134106
-
Salicylates inhibit NF-κB activation and enhance TNF-α-induced apoptosis in human pancreatic cancer cells
-
McDade TP, Perugini RA, Vittimberga FJ Jr, Carrigan RC, Callery MP: Salicylates inhibit NF-κB activation and enhance TNF-α-induced apoptosis in human pancreatic cancer cells. J Surg Res 1999;83:56-61.
-
(1999)
J Surg Res
, vol.83
, pp. 56-61
-
-
McDade, T.P.1
Perugini, R.A.2
Vittimberga Jr., F.J.3
Carrigan, R.C.4
Callery, M.P.5
-
191
-
-
0035929351
-
Peroxisome proliferator-activated receptor γ induces pancreatic cancer cell apoptosis
-
Eibl G, Wente MN, Reber HA, Hines OJ: Peroxisome proliferator-activated receptor γ induces pancreatic cancer cell apoptosis. Biochem Biophys Res Commun 2001;287:522-529.
-
(2001)
Biochem Biophys Res Commun
, vol.287
, pp. 522-529
-
-
Eibl, G.1
Wente, M.N.2
Reber, H.A.3
Hines, O.J.4
-
192
-
-
0037457422
-
Usage of the NF-κB inhibitor sulfasalazine as sensitizing agent in combined chemotherapy of pancreatic cancer
-
Muerkoster S, Arlt A, Witt M, Gehrz A, Haye S, March C, Grohmann F, Wegehenkel K, Kalthoff H, Folsch UR, Schafer H: Usage of the NF-κB inhibitor sulfasalazine as sensitizing agent in combined chemotherapy of pancreatic cancer. Int J Cancer 2003;104:469-476.
-
(2003)
Int J Cancer
, vol.104
, pp. 469-476
-
-
Muerkoster, S.1
Arlt, A.2
Witt, M.3
Gehrz, A.4
Haye, S.5
March, C.6
Grohmann, F.7
Wegehenkel, K.8
Kalthoff, H.9
Folsch, U.R.10
Schafer, H.11
-
193
-
-
0034307305
-
Inhibition of phosphatidylinositide 3-kinase enhances gemcitabine-induced apoptosis in human pancreatic cancer cells
-
Ng SSW, Tsao MS, Chow S, Hedley DW: Inhibition of phosphatidylinositide 3-kinase enhances gemcitabine-induced apoptosis in human pancreatic cancer cells. Cancer Res 2000;60:5451-5455.
-
(2000)
Cancer Res
, vol.60
, pp. 5451-5455
-
-
Ng, S.S.W.1
Tsao, M.S.2
Chow, S.3
Hedley, D.W.4
-
194
-
-
0142137239
-
Pharmacologic inactivation of kinase suppressor of ras-1 abrogates Ras-mediated pancreatic cancer
-
Xing HR, Cordon-Cardo C, Deng X, Tong W, Campodonico L, Fuks Z, Kolesnick R: Pharmacologic inactivation of kinase suppressor of ras-1 abrogates Ras-mediated pancreatic cancer. Nat Med 2003;9:1266-1268.
-
(2003)
Nat Med
, vol.9
, pp. 1266-1268
-
-
Xing, H.R.1
Cordon-Cardo, C.2
Deng, X.3
Tong, W.4
Campodonico, L.5
Fuks, Z.6
Kolesnick, R.7
-
195
-
-
0035893740
-
Evaluation of farnesyl:Protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models
-
Lobell RB, Omer CA, Abrams MT, Bhimnathwala HG, Brucker MJ, Buser CA, Davide JP, deSolms SJ, Dinsmore CJ, Ellis-Hutchings MS, Kral AM, Liu D, Lumma WC, Machotka SV, Rands E, Williams TM, Graham SL, Hartman GD, Oliff AI, Heimbrook DC, Kohl NE: Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models. Cancer Res 2001;61:8758-8768.
-
(2001)
Cancer Res
, vol.61
, pp. 8758-8768
-
-
Lobell, R.B.1
Omer, C.A.2
Abrams, M.T.3
Bhimnathwala, H.G.4
Brucker, M.J.5
Buser, C.A.6
Davide, J.P.7
Desolms, S.J.8
Dinsmore, C.J.9
Ellis-Hutchings, M.S.10
Kral, A.M.11
Liu, D.12
Lumma, W.C.13
Machotka, S.V.14
Rands, E.15
Williams, T.M.16
Graham, S.L.17
Hartman, G.D.18
Oliff, A.I.19
Heimbrook, D.C.20
Kohl, N.E.21
more..
-
196
-
-
0038538402
-
Farnesyl transferase inhibitors - A novel approach in the treatment of advanced pancreatic carcinomas
-
Dempke WC: Farnesyl transferase inhibitors - A novel approach in the treatment of advanced pancreatic carcinomas. Anticancer Res 2003;23:813-818.
-
(2003)
Anticancer Res
, vol.23
, pp. 813-818
-
-
Dempke, W.C.1
-
198
-
-
0035211278
-
Antioxidants inhibit cytokine production and suppress NF-κB activation in CAPAN-1 and CAPAN-2 cell lines
-
Blanchard JA, Barve S, Joshi-Barve S, Talwalker R, Gates LK Jr: Antioxidants inhibit cytokine production and suppress NF-κB activation in CAPAN-1 and CAPAN-2 cell lines. Dig Dis Sci 2001;46:2768-2772.
-
(2001)
Dig Dis Sci
, vol.46
, pp. 2768-2772
-
-
Blanchard, J.A.1
Barve, S.2
Joshi-Barve, S.3
Talwalker, R.4
Gates Jr., L.K.5
-
199
-
-
0037444154
-
The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma
-
Cullen JJ, Weydert C, Hinkhouse MM, Ritchie J, Domann FE, Spitz D, Oberley LW: The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma. Cancer Res 2003;63:1297-1303.
-
(2003)
Cancer Res
, vol.63
, pp. 1297-1303
-
-
Cullen, J.J.1
Weydert, C.2
Hinkhouse, M.M.3
Ritchie, J.4
Domann, F.E.5
Spitz, D.6
Oberley, L.W.7
-
200
-
-
0035114253
-
Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo
-
Ghaneh P, Greenhalf W, Humphreys M, Wilson D, Zumstein L, Lemoine NR, Neoptolemos JP: Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo. Gene Ther 2001;8:199-208.
-
(2001)
Gene Ther
, vol.8
, pp. 199-208
-
-
Ghaneh, P.1
Greenhalf, W.2
Humphreys, M.3
Wilson, D.4
Zumstein, L.5
Lemoine, N.R.6
Neoptolemos, J.P.7
-
201
-
-
0036249661
-
Influence of p53 status on radiation and 5-fluorouracil synergy in pancreatic cancer cells
-
Mohiuddin M, Chendil D, Dey S, Alcock RA, Regine W, Mohiuddin M, Ahmed MM: Influence of p53 status on radiation and 5-fluorouracil synergy in pancreatic cancer cells. Anticancer Res 2002;22:825-830.
-
(2002)
Anticancer Res
, vol.22
, pp. 825-830
-
-
Mohiuddin, M.1
Chendil, D.2
Dey, S.3
Alcock, R.A.4
Regine, W.5
Mohiuddin, M.6
Ahmed, M.M.7
-
202
-
-
0034067359
-
Differential expression of transforming growth factor-β receptors in human pancreatic adenocarcinoma
-
Venkatasubbarao K, Ahmed MM, Mohiuddin M, Swiderski C, Lee E, Gower WR Jr, Salhab KF, McGrath P, Strodel W, Freeman JW: Differential expression of transforming growth factor-β receptors in human pancreatic adenocarcinoma. Anticancer Res 2000;20:43-51.
-
(2000)
Anticancer Res
, vol.20
, pp. 43-51
-
-
Venkatasubbarao, K.1
Ahmed, M.M.2
Mohiuddin, M.3
Swiderski, C.4
Lee, E.5
Gower Jr., W.R.6
Salhab, K.F.7
McGrath, P.8
Strodel, W.9
Freeman, J.W.10
-
203
-
-
0037127220
-
Restoration of transforming growth factor-β signaling enhances radiosensitivity by altering the Bcl-2/Bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2
-
Ahmed MM, Alcock RA, Chendil D, Dey S, Das A, Venkatasubbarao K, Mohiuddin M, Sun L, Strodel WE, Freeman JW: Restoration of transforming growth factor-β signaling enhances radiosensitivity by altering the Bcl-2/Bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2. J Biol Chem 2002;277:2234-2246.
-
(2002)
J Biol Chem
, vol.277
, pp. 2234-2246
-
-
Ahmed, M.M.1
Alcock, R.A.2
Chendil, D.3
Dey, S.4
Das, A.5
Venkatasubbarao, K.6
Mohiuddin, M.7
Sun, L.8
Strodel, W.E.9
Freeman, J.W.10
|