The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer

Genes and Development

Volumn 17, Issue 24, 2003, Pages 3127-3138

  Lewis, Brian C ^a,b   Klimstra, David S ^a   Varmus, Harold E ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

c Myc; Pancreatic cancer; Progenitor cell; PyMT; RCAS; Transdifferentiation

Indexed keywords

RETROVIRUS VECTOR; VIRUS MIDDLE T ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVIAN LEUKOSIS ONCOVIRUS; CANCER CYTODIAGNOSIS; CELL LINEAGE; CONTROLLED STUDY; DISEASE MARKER; HISTOPATHOLOGY; MOUSE; MULTIPOTENT STEM CELL; NONHUMAN; ONCOGENE C MYC; PANCREAS CARCINOMA; PRIORITY JOURNAL; PROMOTER REGION; RETROVIRUS; SIGNAL TRANSDUCTION; STEM CELL; TARGET CELL; TISSUE SECTION; TRANSGENIC MOUSE; VIRUS CARCINOGENESIS; VIRUS MUTATION; VIRUS ONCOGENE;

ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; AVIAN LEUKOSIS VIRUS; AVIAN PROTEINS; CARCINOMA IN SITU; CARCINOMA, ACINAR CELL; CARCINOMA, PANCREATIC DUCTAL; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYSTADENOCARCINOMA; DNA-BINDING PROTEINS; GENETIC VECTORS; HUMANS; INSULINOMA; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PAIRED BOX TRANSCRIPTION FACTORS; PANCREAS; PANCREATIC ELASTASE; PANCREATIC NEOPLASMS; PLASMIDS; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, VIRUS; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P14ARF;

ANIMALIA; AVES; AVIAN LEUKOSIS VIRUS; AVIAN RETROVIRUSES; MUS MUSCULUS; ONCOVIRINAE; POLYOMAVIRUS; SUBGROUP A; UNIDENTIFIED RETROVIRUS;

EID: 0346731132     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1140403     Document Type: Article

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