The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice

Development

Volumn 122, Issue 5, 1996, Pages 1409-1416

  Ahlgren, U ^a   Jonsson, J ^a   Edlund, H ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

Apancreatic; Epitheliomesenchymal interactions; Epithelium; Homeodomain; ipf1 pdx1; Mesenchyme; Morphogenesis; Mouse; Pancreas

Indexed keywords

GLUCAGON; INSULIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; EMBRYO; EPITHELIUM; GENE MUTATION; GLUCAGON RELEASE; HOMEOBOX; INSULIN RELEASE; MESENCHYME; MORPHOGENESIS; MOUSE; NONHUMAN; PANCREAS; PANCREAS ISLET CELL; PRIORITY JOURNAL;

ANIMALS; BASE SEQUENCE; CELL COMMUNICATION; EPITHELIUM; GLUCAGON; HOMEODOMAIN PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INSULIN; ISLETS OF LANGERHANS; MESODERM; MICE; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; MORPHOGENESIS; PANCREAS; TRANS-ACTIVATORS;

ANIMALIA;

EID: 0029950724     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Alpert, S., Hanahan, D. and Teitelman, G. (1988). Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons. Cell 53, 295-308.
2. Ang, S.-L., Wierda, A., Wong, D., StevensK. A., Cascio, S., Rossant, J. and Zareth, K. S. (1993). The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins. Development 119, 1301-1315.
3. Echelard, V., Epstein, D., St-Jacques, B., Shen, L., Mohler, J. and McMahon, J. and McMahon, A. (1993). Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.
4. Gittes, G. K. and Rutter, W. J. (1992). Onset of cell-specific gene expression in the developing mouse pancreas. Proc. Natl. Acad. Sci. USA 89, 1128-1132.
5. Gittes, G. and Galante, P. E. (1993). A culture system for the study of pancreatic organogenesis. J. Tiss. Cult. Meth. 15, 23-28.
6. Golosow, N. and Grobstein, C. (1962). Epitheliomesenchymal interaction in pancreatic morphogenesis. Der. Biol. 4, 242-255.
7. Guz, Y., Montminy, M. R., Stein, R., Leonard, J., Gamer, L. W., Wright, C. V. E. and Teitelman, G. (1995). Expression of murine STF-1, a putative insulin gene transcription factor, in β-cells of pancreas, duodenal epithelium, and pancreatic exocrine and endocrine progenitors during ontogeny. Development 121, 11-18.
8. Herrera P.-L., Huarte, J., Sanvito, F., Meda, P., Orci, P. and Vassalli, J. D. (1991). Embryogenesis of the embryonic endocrine pancreas; early expression of pancreatic polypeptide gene. Development 113, 1257-1265.
9. Herrera P.-L., Huarte, J., Zuffery, R., Nichols, A., Mermillod, B., Philippe, J., Muniesa, P., Sanvito, F., Orci, P. and Vassalli, J. D. (1994). Ablation of islet endocrine cells by targeted expression of hormone promoter-driven toxigenes. Proc. Natl. Acad. Sci. USA 91, 12999-13003.
10. Jonsson, J., Carlsson, L., Edlund, T. and Edlund, H. (1994). Insulin promoter factor 1 is required for pancreas development in mice. Nature 371, 606-609.
11. Krauss, S., Concordet, J. P. and Ingham, P. W. (1993). A functionally conserved homologue of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos. Cell 75, 1431-1444.
12. Leonard, J., Peers, B., Johnson, T., Ferreri, K., Lee, S. and Montminy, M. R. (1993). Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol. Endocrin. 7, 1275-1283.
13. Levine, S., Pictet, R. and Rutter, W. J. (1973). Control of cell-proliferation and cytodifferentiation by a factor reacting with the cell surface. Nature New Biol. 246, 49-42.
14. Miller, C. P., McGehee Jr, R. E. and Habener, J. F. (1994). IDX-1 : a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene. EMBO J. 13, 1145-1158.
15. Monaghan, A. P., Kaestner, K. H., Grau, E. and Schutz, G. (1993). Postimplantation expression patterns indicate a role for the mouse fork head/HNF-3α, β and γ genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm. Development 119, 567-578.
16. Ohlsson, H., Karlsson, K. and Edlund, T. (1993). IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J. 12, 4251-4259.
17. Pictet, R. and Rutter, W. J. (1972). Development of the embryonic endocrine pancreas. In Handbook of Physiology, section 7, vol. 1, American Physiological Society (ed. Steiner. D. F. and Frenkel, N.), pp. 25-66. Washinton DC: Williams and Wilkins.
18. Riddle, R., Johnson, R., Laufer, E. and Tabin, C. (1993). Sonic hedgehog mediates the polarising activity of the ZPA. Cell 75, 1401-1416.
19. Roelink, H., Augsburger, A., Heemskerk, J., Korzh, V., Norlin, S., Ruiz I Altaba, A., Tanabe, Y., Placzek, M., Edlund, T., Jessell, T. and Dodd, J. (1994). Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord. Cell 76, 761-775.
20. Ruiz i Altaba, A., Prezioso, V. R., Darnell, J. E. and Jessell, T. M. (1993). Sequential expression of HNF-3β and HNF-3α by embryonic organizing centers: the dorsal lip/node, notochord and floor plate. Mech. Dev. 44, 91-108.
21. Sasaki, H. and Hogan, B. L. M. (1993). HNF-3β as a regulator of floor plate development. Cell 76, 103-115.
22. Serup, P., Petersen, H. V., Pedersen, E. E., Edlund, H., Leonard, J., Petersen, J. S., Larsson, L. I. and Madsen, O. D. (1995). The homeodomain protein IPF1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loophelix factor binding site. Biochem. J. 310, 997-1003.
23. Schaeren-Wiemers, N. and Gerfin-Moser, A. (1993). A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labeled cRNA probes. Histochemistry 100, 431-440.
24. Slack, J.W. Developmental biology of the pancreas. (1995). Development 121, 1569-1580.
25. Spooner, B. S., Walther, B. T. and Rutter, W. J. (1970). The development of the dorsal and ventral pancreas in vivo and in vitro. J. Cell. Biol. 47, 235-246.
26. Teitelman, G., Alpert, S., Polak, J. M., Mertinez, A. and Hanahan, D. (1993). Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon, and the neuronal proteins tyrosine hydroxylase and neuropeptide Y but not pancreatic polypepetide. Development 118, 1031-1039.
27. Tsuchida, T., Ensini, M., Morton, S. B., Baldassare, M., Edlund, T., Jessell, T. and Yamada, T. (1994). Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Cell 79, 957-970.
28. Wessells, N. K. and Cohen, J. H. (1967). Early pancreas organogenesis: morphogenesis, tissue interactions and mass effects. Dev. Biol. 15, 237-270.