-
1
-
-
0036157392
-
Cancer statistics, 2002
-
Jemal A, Thomas A, Murray T, et al: Cancer statistics, 2002. CA Cancer J Clin 52:23-47, 2002
-
(2002)
CA Cancer J Clin
, vol.52
, pp. 23-47
-
-
Jemal, A.1
Thomas, A.2
Murray, T.3
-
2
-
-
0034110011
-
Current approaches and future strategies for pancreatic carcinoma
-
Wolff R, Chiao P, Lenzi R. et al: Current approaches and future strategies for pancreatic carcinoma. Invest New Drugs 18:43-56, 2000
-
(2000)
Invest New Drugs
, vol.18
, pp. 43-56
-
-
Wolff, R.1
Chiao, P.2
Lenzi, R.3
-
3
-
-
0033988823
-
A multispecialty approach to the diagnosis and management of pancreatic cancer
-
Hawes RH, Xiong Q, Waxman I, et al: A multispecialty approach to the diagnosis and management of pancreatic cancer. Am J Gastroenterol 95:17-31, 2000
-
(2000)
Am J Gastroenterol
, vol.95
, pp. 17-31
-
-
Hawes, R.H.1
Xiong, Q.2
Waxman, I.3
-
4
-
-
8944261362
-
A phase II trial of gemcitabine in patients with 5-FU-refractory pancreatic cancer
-
Rothenberg ML, Moore MJ, Cripps MC, et al: A phase II trial of gemcitabine in patients with 5-FU-refractory pancreatic cancer. Ann Oncol 7:347-353, 1996
-
(1996)
Ann Oncol
, vol.7
, pp. 347-353
-
-
Rothenberg, M.L.1
Moore, M.J.2
Cripps, M.C.3
-
5
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
-
Burris HA 3rd, Moore MJ, Andersen J, et al: Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial. J Clin Oncol 15:2403-2413, 1997
-
(1997)
J Clin Oncol
, vol.15
, pp. 2403-2413
-
-
Burris III, H.A.1
Moore, M.J.2
Andersen, J.3
-
6
-
-
0037010091
-
Epidermal growth factor receptor-targeted therapy for pancreatic cancer
-
Xiong HQ, Abbruzzese JL: Epidermal growth factor receptor-targeted therapy for pancreatic cancer. Semin Oncol 29:31-37, 2002 (5 suppl 14)
-
(2002)
Semin Oncol
, vol.29
, Issue.5 SUPPL. 14
, pp. 31-37
-
-
Xiong, H.Q.1
Abbruzzese, J.L.2
-
7
-
-
0025343230
-
Signal transduction by receptors with tyrosine kinase activity
-
Ullrich A, Schlessinger J: Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212, 1960
-
(1960)
Cell
, vol.61
, pp. 203-212
-
-
Ullrich, A.1
Schlessinger, J.2
-
8
-
-
0034992521
-
The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification
-
Prenzel N, Fischer OM, Streit S, et al: The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr Relat Cancer 8:11-31, 2001
-
(2001)
Endocr Relat Cancer
, vol.8
, pp. 11-31
-
-
Prenzel, N.1
Fischer, O.M.2
Streit, S.3
-
9
-
-
0026595557
-
The epidermal growth factor receptor in human pancreatic cancer
-
Lemoine NR, Hughes CM, Barton CM, et al: The epidermal growth factor receptor in human pancreatic cancer. J Pathol 166:7-12, 1992
-
(1992)
J Pathol
, vol.166
, pp. 7-12
-
-
Lemoine, N.R.1
Hughes, C.M.2
Barton, C.M.3
-
10
-
-
0027293748
-
Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness
-
Yamanaka Y, Friess H, Kobrin MS, et al: Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness. Anticancer Res 13:565-569, 1993
-
(1993)
Anticancer Res
, vol.13
, pp. 565-569
-
-
Yamanaka, Y.1
Friess, H.2
Kobrin, M.S.3
-
11
-
-
0032423809
-
Epidermal growth factor and its receptor as prognostic indicators in Chinese patients with pancreatic cancer
-
Dong M, Nio Y, Quo KJ, et al: Epidermal growth factor and its receptor as prognostic indicators in Chinese patients with pancreatic cancer. Anticancer Res 18:4613-4620, 1998
-
(1998)
Anticancer Res
, vol.18
, pp. 4613-4620
-
-
Dong, M.1
Nio, Y.2
Quo, K.J.3
-
12
-
-
0027412319
-
Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: A model of glioblastoma multiforme pathophysiology
-
Goldman CK, Kim J, Wong WL, et al: Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: A model of glioblastoma multiforme pathophysiology. Mol Biol Cell 4:121-133, 1993
-
(1993)
Mol Biol Cell
, vol.4
, pp. 121-133
-
-
Goldman, C.K.1
Kim, J.2
Wong, W.L.3
-
13
-
-
0022501030
-
Transforming growth factor-α: A more potent angiogenic mediator than epidermal growth factor
-
Schreiber AB, Winkler ME, Derynck R: Transforming growth factor-α: A more potent angiogenic mediator than epidermal growth factor. Science 232:1250-1253, 1986
-
(1986)
Science
, vol.232
, pp. 1250-1253
-
-
Schreiber, A.B.1
Winkler, M.E.2
Derynck, R.3
-
14
-
-
0020933452
-
Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors
-
Sato JD, Kawamoto T, Le AD, et al: Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors. Mol Biol Med 1:511-529, 1983
-
(1983)
Mol Biol Med
, vol.1
, pp. 511-529
-
-
Sato, J.D.1
Kawamoto, T.2
Le, A.D.3
-
15
-
-
0021254542
-
Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity
-
Gill GN, Kawamoto T, Cochet C, et al: Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase activity. J Biol Chem 259:7755-7760, 1984
-
(1984)
J Biol Chem
, vol.259
, pp. 7755-7760
-
-
Gill, G.N.1
Kawamoto, T.2
Cochet, C.3
-
16
-
-
0028819660
-
Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model
-
Goldstein NI, Prewett M, Zuklys K, et al: Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model. Clin Cancer Res 1:1311-1318, 1995
-
(1995)
Clin Cancer Res
, vol.1
, pp. 1311-1318
-
-
Goldstein, N.I.1
Prewett, M.2
Zuklys, K.3
-
17
-
-
0034779291
-
The EGFR as a target for anticancer therapy-focus on cetuximab
-
Baselga J: The EGFR as a target for anticancer therapy-focus on cetuximab. Eur J Cancer 37:S16-S22, 2001 (suppl 4)
-
(2001)
Eur J Cancer
, vol.37
, Issue.SUPPL. 4
-
-
Baselga, J.1
-
18
-
-
0034235955
-
Epidermal growth factor receptor blockade by antibody IMC-C225 inhibits growth of a human pancreatic carcinoma xenograft in nude mice
-
Overholser JP, Prewett MC, Hooper AT, et al: Epidermal growth factor receptor blockade by antibody IMC-C225 inhibits growth of a human pancreatic carcinoma xenograft in nude mice. Cancer 89:74-82, 2000
-
(2000)
Cancer
, vol.89
, pp. 74-82
-
-
Overholser, J.P.1
Prewett, M.C.2
Hooper, A.T.3
-
19
-
-
18844473781
-
Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms
-
Bruns CJ, Harbison MT, Davis DW, et al: Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms. Clin Cancer Res 6:1936-1948, 2000
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1936-1948
-
-
Bruns, C.J.1
Harbison, M.T.2
Davis, D.W.3
-
20
-
-
19244366949
-
Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin
-
Baselga J, Pfister D, Cooper MR, et al: Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin. J Clin Oncol 18:904-914, 2000
-
(2000)
J Clin Oncol
, vol.18
, pp. 904-914
-
-
Baselga, J.1
Pfister, D.2
Cooper, M.R.3
-
21
-
-
0021363327
-
Growth inhibition of human tumor cells in athymic mice by anti-epidermal growth factor receptor monoclonal antibodies
-
Masui H, Kawamoto T, Sato JD, et al: Growth inhibition of human tumor cells in athymic mice by anti-epidermal growth factor receptor monoclonal antibodies. Cancer Res 44:1002-1007, 1984
-
(1984)
Cancer Res
, vol.44
, pp. 1002-1007
-
-
Masui, H.1
Kawamoto, T.2
Sato, J.D.3
-
23
-
-
0031409362
-
Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy
-
Mendelsohn J: Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy. Clin Cancer Res 3:2703-2707, 1997
-
(1997)
Clin Cancer Res
, vol.3
, pp. 2703-2707
-
-
Mendelsohn, J.1
-
24
-
-
0028969852
-
Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin
-
Wu X, Fan Z, Masui H, Rosen N, et al: Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin. J Clin Invest 95:1897-1905, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 1897-1905
-
-
Wu, X.1
Fan, Z.2
Masui, H.3
Rosen, N.4
-
25
-
-
0035927546
-
The monoclonal antibody 225 activates caspase-8 and induces apoptosis through a tumor necrosis factor receptor family-independent pathway
-
Liu B, Fan Z: The monoclonal antibody 225 activates caspase-8 and induces apoptosis through a tumor necrosis factor receptor family-independent pathway. Oncogene 20:3726-3734, 2001
-
(2001)
Oncogene
, vol.20
, pp. 3726-3734
-
-
Liu, B.1
Fan, Z.2
-
26
-
-
0037106273
-
Targeting the epidermal growth factor receptor for cancer therapy
-
Mendelsohn J: Targeting the epidermal growth factor receptor for cancer therapy. J Clin Oncol 20:1S-13S, 2002 (suppl 18)
-
(2002)
J Clin Oncol
, vol.20
, Issue.SUPPL. 18
-
-
Mendelsohn, J.1
-
27
-
-
0037111274
-
Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation
-
Buchsbaum DJ, Bonner JA, Grizzle WE, et al: Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation. Int J Radiat Oncol Biol Phys 54:1180-1193, 2002
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 1180-1193
-
-
Buchsbaum, D.J.1
Bonner, J.A.2
Grizzle, W.E.3
-
28
-
-
0038717931
-
Restoring apoptosis in pancreatic cancer cells by targeting the nuclear factor-kappaB signaling pathway with the anti-epidermal growth factor antibody IMC-C225
-
Sclabas GM, Fujioka S, Schmidt C, et al: Restoring apoptosis in pancreatic cancer cells by targeting the nuclear factor-kappaB signaling pathway with the anti-epidermal growth factor antibody IMC-C225. J Gastrointest Surg 7:37-43, 2003
-
(2003)
J Gastrointest Surg
, vol.7
, pp. 37-43
-
-
Sclabas, G.M.1
Fujioka, S.2
Schmidt, C.3
-
29
-
-
0036096775
-
Inhibition of angiogenesis by the antiepidermal growth factor receptor antibody ImClone C225 in androgen-independent prostate cancer growing orthotopically in nude mice
-
Karashima T, Sweeney P, Slaton JW, et al: Inhibition of angiogenesis by the antiepidermal growth factor receptor antibody ImClone C225 in androgen-independent prostate cancer growing orthotopically in nude mice. Clin Cancer Res 8:1253-1264, 2002
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1253-1264
-
-
Karashima, T.1
Sweeney, P.2
Slaton, J.W.3
-
30
-
-
0035398631
-
Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies
-
Hidalgo M, Siu LL, Nemunaitis J, et al: Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies. J Clin Oncol 19:3267-3279, 2001
-
(2001)
J Clin Oncol
, vol.19
, pp. 3267-3279
-
-
Hidalgo, M.1
Siu, L.L.2
Nemunaitis, J.3
-
31
-
-
0037106377
-
Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: Results of a phase I trial
-
Herbst RS, Maddox AM, Rothenberg ML, et al: Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: Results of a phase I trial. J Clin Oncol 20:3815-3825, 2002
-
(2002)
J Clin Oncol
, vol.20
, pp. 3815-3825
-
-
Herbst, R.S.1
Maddox, A.M.2
Rothenberg, M.L.3
-
32
-
-
0035724536
-
Cutaneous side-effects in cancer patients treated with the antiepidermal growth factor receptor antibody C225
-
Busam KJ, Capodieci P, Motzer R, et al: Cutaneous side-effects in cancer patients treated with the antiepidermal growth factor receptor antibody C225. Br J Dermatol 144:1169-1176, 2001
-
(2001)
Br J Dermatol
, vol.144
, pp. 1169-1176
-
-
Busam, K.J.1
Capodieci, P.2
Motzer, R.3
-
33
-
-
0037674062
-
Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck
-
Cohen EE, Rosen F, Stadler WM, et al: Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol 21:1980-1987, 2003
-
(2003)
J Clin Oncol
, vol.21
, pp. 1980-1987
-
-
Cohen, E.E.1
Rosen, F.2
Stadler, W.M.3
-
34
-
-
0002823211
-
Cetuximab (IMC-C225) plus irinotecan (CPT-11) is active in CPT-11-refractory colorectal cancer (CRC) that expresses epidermal growth factor receptor (EGFR)
-
abstr 7
-
Saltz L, Rubin M, Hochster H, et al: Cetuximab (IMC-C225) plus irinotecan (CPT-11) is active in CPT-11-refractory colorectal cancer (CRC) that expresses epidermal growth factor receptor (EGFR). Proc Am Soc Clin Oncol 20:3a, 2001 (abstr 7)
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
-
-
Saltz, L.1
Rubin, M.2
Hochster, H.3
-
35
-
-
0027290650
-
Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies
-
Baselga J, Norton L, Masui H, et al: Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies. J Natl Cancer Inst 85:1327-1333, 1993
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1327-1333
-
-
Baselga, J.1
Norton, L.2
Masui, H.3
-
36
-
-
0036094194
-
Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts
-
Prewett MC, Hooper AT, Bassi R, et al: Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts. Clin Cancer Res 8:994-1003, 2002
-
(2002)
Clin Cancer Res
, vol.8
, pp. 994-1003
-
-
Prewett, M.C.1
Hooper, A.T.2
Bassi, R.3
|