Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 24, 1996, Pages 13742-13747

  Alcorta, David A ^a   Xiong, Yue ^b   Phelps, Dawn ^b   Hannon, Greg ^c   Beach, David ^c   Barrett, J Carl ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; ENZYME INHIBITOR; GENE PRODUCT; MESSENGER RNA; RETINOBLASTOMA PROTEIN;

CELL AGING; CELL IMMORTALIZATION; CELL PROLIFERATION; CONFERENCE PAPER; DIPLOIDY; EMBRYO; ENZYME INHIBITION; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; MESSENGER RNA SYNTHESIS; NEWBORN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SENESCENCE;

EID: 0030477686     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.24.13742     Document Type: Article

References (37)

1. Hayflick, L. (1965) Exp. Cell Res. 37, 614-636.
2. Shay, J. W., Pereira-Smith, O. M. & Wright, W. E. (1991) Exp. Cell Res. 196, 33-39.
3. Hara, E., Tsurui, H., Shinozaki, A., Nakada, S. & Oda, K. (1991) Biochem. Biophys. Res. Commun. 179, 528-534.
4. Stein, G. H., Beeson, M. & Gordon, L. (1990) Science 249, 666-669.
5. Weinberg, R. A. (1995) Cell 81, 323-330.
6. Cristofalo, V. J., Pignolo, R. J., Cianciarulo, F. L., DiPaolo, B. R. & Rotenberg, M. O. (1992) Exp. Gerontol. 27, 429-432.
7. Dulic, V., Drullinger, L. F., Lees, E., Reed, S. I. & Stein, G. H. (1993) Proc. Natl. Acad. Sci. USA 90, 11034-11038.
8. Lucibello, F. C., Sewing, A., Brusselbach, S., Burger, C. & Muller, R. (1993) J. Cell. Sci. 105, 123-133.
9. Noda, A., Ning, Y., Venable, S. F., Pereira-Smith, O. M. & Smith, J. R. (1994) Exp. Cell Res. 211, 90-98.
10. Sherr, C. J. & Roberts, J. M. (1995) Genes Dev. 9, 1149-1163.
11. Serrano, M., Hannon, G. J. & Beach, D. (1993) Nature (London) 366, 704-707.
12. Kamb, A., Gruis, N. A., Weaver-Feldhaus, J., Liu, Q., Harshman, K., Tavtigian, S. V., Stockert, E., Day, R. R., Johnson, B. E. & Skolnick, M. H. (1994) Science 264, 436-440.
13. Serrano, M., Lee, H.-W., Chin, L., Cordon-Cardo, C., Beach, D. & DePinho, R. A. (1996) Cell 85, 27-37.
14. Brugarolas, J., Chandrasekaran, C., Gordon, J. I., Beach, D., Jacks, T. & Hannon, G. J. (1995) Nature (London) 377, 552-557.
15. Nakayama, K., Ishida, N., Shirane, M., Inomata, A., Inoue, T., Shishido, N., Horii, I., Loh, D. Y. & Nakayama, K.-I. (1996) Cell 86, 707-720.
16. Fero, M. L., Rivkin, M., Tasch, T., Porter, P., Carow, C. E., Firpo, E., Polyak, K., Tsai, L.-H., Broudy, V., Perlmutter, R. M., Kaushansky, K. & Roberts, J. M. (1996) Cell 86, 733-744.
17. Kiyokawa, H., Kineman, R. D., Manova-Todorova, K. O., Soares, V. C., Hoffman, E. S., Ono, M., Khanam, D., Hayday, A. C., Frohman, L. A. & Koff, A. (1996) Cell 86, 721-732.
18. Hara, E., Smith, R., Parry, D., Tahara, H., Stone, S. & Peters, G. (1996) Mol. Cell Biol. 16, 859-867.
19. Wong, H. & Riahowol, K. (1996) Exp. Gerontol. 31, 311-325.
20. Jenkins, C. W. & Xiong, Y. (1995) in Cell Cycle: Material and Methods, ed. Pagano, M. (Springer, New York), pp. 250-263.
21. Cristofalo, V. J. & Pignolo, R. J. (1993) Physiol. Rev. 73, 617-638.
22. Bond, J. A., Blaydes, J. P., Rowson, J., Haughton, M. F., Smith, J. R., Wynford Thomas, D. & Wyllie, F. S. (1995) Cancer Res, 55, 2404-2409.
23. Lukas, J., Parry, D., Aagaard, L., Mann, D. J., Bartkova, J., Strauss, M., Peters, G. & Bartek, J. (1995) Nature (London) 375, 503-506.
24. Stone, S., Jiang, P., Dayananth, P., Tavtigian, S. V., Katcher, H., Parry, D., Peters, G. & Kamh, A. (1995) Cancer Res. 55, 2988-2994.
25. Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R. & Beach, D. (1993) Nature (London) 366, 701-704.
26. Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K. & Elledge, S. J. (1993) Cell 75, 805-816.
27. el-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W. & Vogelstein, B. (1993) Cell 75, 817-825.
28. Li, Y., Nichols, M. A., Shay, J. W. & Xiong, Y. (1994) Cancer Res. 54, 6078-6082.
29. Tam, S. W., Shay, J. W. & Pagano, M. (1994) Cancer Res. 54, 5816-5820.
30. Soucek, T., Pusch, O., Hengstschlager-Ottnad, E., Wawra, E., Bernaschek, G. & Hengstschlager, M. (1995) FEBS Lett. 373, 164-169.
31. Afshari, C. A., Nichols, M. A., Xiong, Y. & Mudryj, M. (1996) Cell. Growth Differ. 7, 979-988.
32. Dimri, G. P., Hara, E. & Campisi, J. (1994) J. Biol. Chem. 269, 16180-16186.
33. Nobori, T., Miura, K., Wu, D. J., Lois, A., Takabayashi, K. & Carson, D. A. (1994) Nature (London) 368, 753-756.
34. Hirama, T. & Koeffler, H. P. (1995) Blood 86, 841-854.
35. Marchetti, A., Buttitta, F., Pellegrini, S., Bertacca, G., Lori, A. & Bevilacqua, G. (1995) Int. J. Oncol. 6, 187-189.
36. Terry, L., Boyd, J., Alcorta, D., Lyon, T., Solomon, G., Hannon, G., Berchuk, A., Beach, D. & Barrett, J. C. (1996) Mol. Carcinogen. 16, 221-228.
37. Quelle, D. E., Zindy, F., Ashmun, R. A. & Sherr, C. J. (1995) Cell 83, 993-1000.