Inhibition of constitutive NF-κB activity by IκBαM suppresses tumorigenesis

Oncogene

Volumn 22, Issue 9, 2003, Pages 1365-1370

  Fujioka, Shuichi ^a   Sclabas, Guido M ^a   Schmidt, Christian ^a   Niu, Jiangong ^b   Frederick, Wayne A ^a   Dong, Qiang G ^a   Abbruzzese, James L ^c   Evans, Douglas B ^a   Baker, Cheryl ^a   Chiao, Paul J ^a,b,d  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Angiogenesis; I B ; NF B; Pancreatic cancer; Tumorigenesis

Indexed keywords

CYTOKINE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; PROTEIN BCL 2; PROTEIN BCL XL; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER MODEL; CARCINOGENESIS; CARCINOGENICITY; CELL LINE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; NUDE MOUSE; PANCREAS CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; ANIMALS; BCL-X PROTEIN; ENDOTHELIAL GROWTH FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BCL-2; GENES, REPORTER; HUMANS; I-KAPPA B PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-8; LUCIFERASES; LYMPHOKINES; MICE; MICE, NUDE; MUTATION; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; NF-KAPPA B; PANCREATIC NEOPLASMS; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

ANIMALIA; MUS MUSCULUS;

EID: 0037422205     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206323     Document Type: Article

References (52)

1. Baldwin Jr AS. (1996). Annu. Rev. Immunol., 14, 649-683.
2. Bramhall SR, Allum WH, Jones AG, Allwood A, Cummins C and Neoptolemos JP. (1995). Br. J. Surg., 82, 111-115.
3. Breslin TM, Hess KR, Harbison DB, Jean ME, Cleary KR, Dackiw AP, Wolff RA, Abbruzzese JL, Janjan NA, Crane CH, Vauthey JN, Lee JE, Pisters PW and Evans DB. (2001). Ann. Surg. Oncol., 8, 123-132.
4. Chang TC, Hung MW, Jiang SY, Chu JT, Chu LL and Tsai LC. (1997). FEBS Lett., 415, 11-15.
5. Chiao PJ, Miyamoto S and Verma IM. (1994). Proc. Natl Acad. Sci. USA, 91, 28-32.
6. Dejardin E, Bonizzi G, Bellahcene A, Castronovo V, Merville MP and Bours V. (1995). Oncogene, 11, 1835-1841.
7. Dong QG, Sclabas GM, Fujioka S, Schmidt C, Peng B, Wu T, Tsao MS, Evans DB, Abbruzzese JL, McDonnell TJ and Chiao PJ. (2002). Oncogene, 21, 6510-6519.
8. Ferrara N. (1995). Breast Cancer Res. Treat., 36, 127-137.
9. Folkman J. (1990). J. Natl. Cancer Inst., 82, 4-6.
10. Folkman J. (1992). Semin. Cancer Biol., 3, 65-71.
11. Folkman J, Watson K, Ingber D and Hanahan D. (1989). Nature, 339, 58-61.
12. Fujioka S, Sclabas GM, Schmidt C, Frederick WA, Dong QG, Abbruzzese JL, Evans DB, Baker C and Chiao PJ. (2003). Clin. Cancer Res., 9, 346-354.
13. Fukumura D, Xavier R, Sugiura T, Chen Y, Park EC, Lu N, Selig M, Nielsen G, Taksir T, Jain RK and Seed B. (1998). Cell, 94, 715-725.
14. Gilmore TD, Koedood M, Piffat KA and White DW. (1996). Oncogene, 13, 1367-1378.
15. Grau AM, Zhang L, Wang W, Ruan S, Evans DB, Abbruzzese JL, Zhang W and Chiao PJ. (1997). Cancer Res., 57, 3929-3934.
16. Grisham MB, Palombella VJ, Elliott PJ, Conner EM, Brand S, Wong HL, Pien C, Mazzola LM, Destree A, Parent L and Adams J. (1999). Methods Enzymol, 300, 345-363.
17. Hu DE, Hori Y and Fan TP. (1993). Inflammation, 17, 135-143.
18. Huang S, Pettaway CA, Uehara H, Bucana CD and Fidler IJ. (2001). Oncogene, 20, 4188-4197.
19. Huang S, Robinson JB, Deguzman A, Bucana CD and Fidler IJ. (2000). Cancer Res., 60, 5334-5339.
20. Jemal A, Thomas A, Murray T and Thun M. (2002). CA Cancer J. Clin., 52, 23-47.
21. Kitajima I, Shinohara T, Bilakovics J, Brown DA, Xu X and Nerenberg M. (1992). Science, 258, 1792-1795.
22. Klingler K, Tchou-Wong KM, Brandli O, Aston C, Kim R, Chi C and Rom WN. (1997). Infect. Immun., 65, 5272-5278.
23. Koch AE, Polverini PJ, Kunkel SL, Harlow LA, DiPietro LA, Elner VM, Elner SG and Strieter RM. (1992). Science, 258, 1798-1801.
24. Lee TH, Avraham H, Lee SH and Avraham S. (2002). J. Biol. Chem., 277, 10445-10451.
25. Leek RD, Lewis CE, Whitehouse R, Greenall M, Clarke J and Harris AL. (1996). Cancer Res., 56, 4625-4629.
26. Leibovich SJ, Polverini PJ, Shepard HM, Wiseman DM, Shively V and Nuseir N. (1987). Nature, 329, 630-632.
27. Liotta LA, Steeg PS and Stetler-Stevenson WG. (1991). Cell, 64, 327-336.
28. Lu D, Thompson JD, Gorski GK, Rice NR, Mayer MG and Yunis JJ. (1991). Oncogene, 6, 1235-1241.
29. Millauer B, Wizigmann-Voos S, Schnurch H, Martinez R, Moller NP, Risau W and Ullrich A. (1993). Cell, 72, 835-846.
30. Mohammad RM, Adsay NV, Philip PA, Pettit GR, Vaitkevicius VK and Sarkar FH. (2001). Anticancer Drugs, 12, 735-740.
31. Moore BE and Bose Jr HR. (1988). Virology, 162, 377-387.
32. Mukaida N, Mahe Y and Matsushima K. (1990). J. Biol. Chem., 265, 21128-21133.
33. Naviaux RK, Costanzi E, Haas M and Verma IM. (1996). J. Virol., 70, 5701-5705.
34. Neri A, Chang CC, Lombardi L, Salina M, Corradini P, Maiolo AT, Chaganti RS and Dalla-Favera R. (1991). Cell, 67, 1075-1087.
35. Ohno H, Takimoto G and McKeithan TW. (1990). Cell, 60, 991-997.
36. Parborell F, Pecci A, Gonzalez O, Vitale A and Tesone M. (2002). Biol. Reprod., 67, 481-486.
37. Passaniti A, Taylor RM, Pili R, Guo Y, Long PV, Haney JA, Pauly RR, Grant DS and Martin GR. (1992). Lab. Invest., 67, 519-528.
38. Sawai H, Yamamoto M, Okada Y, Sato M, Akamo Y, Takeyama H and Manabe T. (2001). Pancreas, 23, 399-405.
39. Schwarte-Waldhoff I, Volpert OV, Bouck NP, Sipos B, Hahn SA, Klein-Scory S, Luttges J, Kloppel G, Graeven U, Eilert-Micus C, Hintelmann A and Schmiegel W. (2000). Proc. Natl. Acad. Sci. USA, 97, 9624-9629.
40. Shono T, Ono M, Izumi H, Jimi SI, Matsushima K, Okamoto T, Kohno K and Kuwano M. (1996). Mol. Cell Biol., 16, 4231-4239.
41. Strieter RM, Kunkel SL, Elner VM, Martonyi CL, Koch AE, Polverini PJ and Elner SG. (1992). Am. J. Pathol., 141, 1279-1284.
42. Sylla BS and Temin HM. (1986). Mol. Cell Biol., 6, 4709-4716.
43. Teraoka H, Sawada T, Nishihara T, Yashiro M, Ohira M, Ishikawa T, Nishino H and Hirakawa K. (2001). Br. J. Cancer, 85, 612-617.
44. Tsai LC, Hung MW, Chang GG and Chang TC. (2000). Anticancer Res., 20, 2441-2448.
45. Tsuzuki Y, Mouta Carreira C, Bockhorn M, Xu L, Jain RK and Fukumura D. (2001). Lab. Invest., 81, 1439-1451.
46. Verma IM, Stevenson JK, Schwarz EM, Van Antwerp D and Miyamoto S. (1995). Genes Dev., 9, 2723-2735.
47. Wang W, Abbruzzese JL, Evans DB and Chiao PJ. (1999a). Oncogene, 18, 4554-4563.
48. Wang W, Abbruzzese JL, Evans DB, Larry L, Cleary KR and Chiao PJ. (1999b). Clin. Cancer Res., 5, 119-127.
49. Xu Z, Friess H, Solioz M, Aebi S, Korc M, Kleeff J and Buchler MW. (2001). Int. J. Cancer, 94, 268-274.
50. Yancopoulos GD, Davis S, Gale NW, Rudge JS, Wiegand SJ and Holash J. (2000). Nature, 407, 242-248.
51. Yoshida A, Yoshida S, Ishibashi T, Kuwano M and Inomata H. (1999). Invest. Ophthalmol. Vis. Sci., 40, 1624-1629.
52. Yoshimura T, Matsushima K, Oppenheim JJ and Leonard EJ. (1987). J. Immunol., 139, 788-793.