Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

Nature

Volumn 424, Issue 6945, 2003, Pages 223-228

  Sage, Julien ^a   Miller, Abigail L ^a   Pérez Mancera, Pedro A ^c   Wysocki, Julianne M ^a   Jacks, Tyler ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; HUMAN ENGINEERING; ONCOLOGY; TUMORS;

GENE FUNCTION;

GENES;

PROTEIN P107; CDKN1A PROTEIN, HUMAN; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; NUCLEAR PROTEIN; PROTEIN P16INK4A; RBL1 PROTEIN, HUMAN; RBL1 PROTEIN, MOUSE;

CANCER; GENE;

ALLELE; ARTICLE; CELL ACTIVITY; CELL CYCLE; EMBRYO; GENE FUNCTION; GENE MUTATION; HUMAN; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RETINOBLASTOMA; TUMOR SUPPRESSOR GENE; ANIMAL; C57BL MOUSE; CELL AGING; CELL LINE; DISEASE MODEL; GENE DELETION; GENE TARGETING; GENETICS; MUTATION; PHYSIOLOGY;

ANIMALS; CELL AGING; CELL CYCLE; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DISEASE MODELS, ANIMAL; GENE DELETION; GENE TARGETING; GENES, RETINOBLASTOMA; GERM-LINE MUTATION; HUMANS; MICE; MICE, INBRED C57BL; NUCLEAR PROTEINS; RETINOBLASTOMA-LIKE PROTEIN P107;

EID: 0038342441     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01764     Document Type: Article

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