-
1
-
-
0030477686
-
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
-
Alcorta, D.A., Xiong, Y., Phelps, D., Hannon, G., Beach, D. and Barrett, J.C. (1996) Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proc. Natl Acad. Sci. USA, 93, 13742-13747.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13742-13747
-
-
Alcorta, D.A.1
Xiong, Y.2
Phelps, D.3
Hannon, G.4
Beach, D.5
Barrett, J.C.6
-
2
-
-
0029111404
-
Increased activity of p53 in senescing fibroblasts
-
Atadja, P., Wong, H., Garkavtsev, I., Veillette, C. and Riabowol, K. (1995) Increased activity of p53 in senescing fibroblasts. Proc. Natl Acad. Sci. USA, 92, 8348-8352.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8348-8352
-
-
Atadja, P.1
Wong, H.2
Garkavtsev, I.3
Veillette, C.4
Riabowol, K.5
-
3
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn, E.H. (2001) Switching and signaling at the telomere. Cell, 106, 661-673.
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
4
-
-
0010045614
-
Extension of life span by introduction of telomerase into normal human cells
-
Bodnar, A.G. et al. (1998) Extension of life span by introduction of telomerase into normal human cells. Science, 279, 349-352.
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
-
5
-
-
0032899038
-
Retinoblastoma protein meets chromatin
-
Brehm, A. and Kouzarides, T. (1999) Retinoblastoma protein meets chromatin. Trends Biochem. Sci., 24, 142-145.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 142-145
-
-
Brehm, A.1
Kouzarides, T.2
-
6
-
-
0027376309
-
A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells
-
Bukrinsky, M.I. et al. (1993) A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells. Nature, 365, 666-669.
-
(1993)
Nature
, vol.365
, pp. 666-669
-
-
Bukrinsky, M.I.1
-
7
-
-
0034774859
-
Cellular senescence, cancer and aging: The telomere connection
-
Campisi, J., Kim, S., Lim, C. and Rubio, M. (2001) Cellular senescence, cancer and aging: The telomere connection. Exp. Gerontol., 36, 1619-1637.
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 1619-1637
-
-
Campisi, J.1
Kim, S.2
Lim, C.3
Rubio, M.4
-
8
-
-
0032440891
-
Dissociation among in vitro telomerase activity, telomere maintenance and cellular immortalization
-
Counter, C.M., Hahn, W.C., Wei, W., Caddle, S.D., Beijersbergen, R.L., Lansdorp, P.M., Sedivy, J.M. and Weinberg, R.A. (1998) Dissociation among in vitro telomerase activity, telomere maintenance and cellular immortalization. Proc. Natl Acad. Sci. USA, 95, 14723-14728.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14723-14728
-
-
Counter, C.M.1
Hahn, W.C.2
Wei, W.3
Caddle, S.D.4
Beijersbergen, R.L.5
Lansdorp, P.M.6
Sedivy, J.M.7
Weinberg, R.A.8
-
9
-
-
0035843952
-
Telomere capping - One strand fits all
-
de Lange, T. (2001) Telomere capping - one strand fits all. Science, 292, 1075-1076.
-
(2001)
Science
, vol.292
, pp. 1075-1076
-
-
De Lange, T.1
-
10
-
-
0023731010
-
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
-
DeCaprio, J.A., Ludlow, J.W., Figge, J., Shew, J.Y., Huang, C.M., Lee, W.H., Marsilio, E., Paucha, E. and Livingston, D.M. (1988) SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell, 54, 275-283.
-
(1988)
Cell
, vol.54
, pp. 275-283
-
-
DeCaprio, J.A.1
Ludlow, J.W.2
Figge, J.3
Shew, J.Y.4
Huang, C.M.5
Lee, W.H.6
Marsilio, E.7
Paucha, E.8
Livingston, D.M.9
-
11
-
-
0023502878
-
Modulation of p53 protein expression during cellular transformation with simian virus 40
-
Deppert, W., Haug, M. and Steinmayer, T. (1987) Modulation of p53 protein expression during cellular transformation with simian virus 40. Mol. Cell. BioL, 7, 4453-4463.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 4453-4463
-
-
Deppert, W.1
Haug, M.2
Steinmayer, T.3
-
12
-
-
0029047362
-
A novel biomarker identifies senescent human cells in culture and in aging skin in vivo
-
Dimri, G.P. et al. (1995) A novel biomarker identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl Acad. Sci. USA, 92, 9363-9367.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
-
13
-
-
0033989829
-
Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14/ARF tumor suppressor
-
Dimri, G.P., Itahana, K., Acosta, M. and Campisi, J. (2000) Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14/ ARF tumor suppressor. Mol. Cell. Biol., 20, 273-285.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 273-285
-
-
Dimri, G.P.1
Itahana, K.2
Acosta, M.3
Campisi, J.4
-
14
-
-
0031710033
-
A third-generation lentivirus vector with a conditional packaging system
-
Dull, T., Zufferey, R., Kelly, M., Mandel, R.J., Nguyen, M., Trono, D. and Naldini, L. (1998) A third-generation lentivirus vector with a conditional packaging system. J. Virol., 72, 8463-8471.
-
(1998)
J. Virol.
, vol.72
, pp. 8463-8471
-
-
Dull, T.1
Zufferey, R.2
Kelly, M.3
Mandel, R.J.4
Nguyen, M.5
Trono, D.6
Naldini, L.7
-
15
-
-
0026724311
-
Structure and function of simian virus 40 large tumor antigen
-
Fanning, E. (1992) Structure and function of simian virus 40 large tumor antigen. Annu. Rev. Biochem., 61, 55-85.
-
(1992)
Annu. Rev. Biochem.
, vol.61
, pp. 55-85
-
-
Fanning, E.1
-
16
-
-
0031935827
-
Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies
-
Gire, V. and Wynford-Thomas, D. (1998) Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies. Mol. Cell. Biol., 18, 1611-1621.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1611-1621
-
-
Gire, V.1
Wynford-Thomas, D.2
-
17
-
-
0022257331
-
Reinitiation of cellular DNA synthesis in BrdU-selected nondividing senescent WI38 cells by simian virus 40 infection
-
Gorman, S.D. and Cristofalo, V.J. (1985) Reinitiation of cellular DNA synthesis in BrdU-selected nondividing senescent WI38 cells by simian virus 40 infection, J. Cell. Physiol., 125, 122-126.
-
(1985)
J. Cell. Physiol.
, vol.125
, pp. 122-126
-
-
Gorman, S.D.1
Cristofalo, V.J.2
-
18
-
-
0027506274
-
Isolation of genetic suppressor elements, inducing resistance to topoisomerase II-interactive cytotoxic drugs, from human topoisomerase II cDNA
-
Gudkov, A.V., Zelnick, C.R., Kazarov, A.R., Thimmapaya, R., Suttle, D.P., Beck, W.T. and Roninson, I.B. (1993) Isolation of genetic suppressor elements, inducing resistance to topoisomerase II-interactive cytotoxic drugs, from human topoisomerase II cDNA. Proc. Natl Acad. Sci. USA, 90, 3231-3235.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 3231-3235
-
-
Gudkov, A.V.1
Zelnick, C.R.2
Kazarov, A.R.3
Thimmapaya, R.4
Suttle, D.P.5
Beck, W.T.6
Roninson, I.B.7
-
19
-
-
0345178412
-
Serum-free growth of human mammary epithelial cells: Rapid clonal growth in defined medium and extended serial passage with pituitary extract
-
Hammond, S. L., Ham, R.G. and Stampfer, M.R. (1984) Serum-free growth of human mammary epithelial cells: rapid clonal growth in defined medium and extended serial passage with pituitary extract. Proc. Natl Acad. Sci. USA, 81, 5435-5439.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 5435-5439
-
-
Hammond, S.L.1
Ham, R.G.2
Stampfer, M.R.3
-
20
-
-
0026055983
-
Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of lifespan in human diploid fibroblasts, TIG-1
-
Hara, E., Tsuri, H., Shinozaki, S. and Oda, K. (1991) Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of lifespan in human diploid fibroblasts, TIG-1. Biochem. Biophys. Res. Commun., 179, 528-534.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.179
, pp. 528-534
-
-
Hara, E.1
Tsuri, H.2
Shinozaki, S.3
Oda, K.4
-
21
-
-
0029670840
-
Regulation of p16/CDKN2 expression and its implications for cell immortalization and senescence
-
Hara, E., Smith, R., Parry, D., Tahara, H., Stone, S. and Peters, G. (1996a) Regulation of p16/CDKN2 expression and its implications for cell immortalization and senescence. Mol. Cell. Biol., 16, 859-867.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 859-867
-
-
Hara, E.1
Smith, R.2
Parry, D.3
Tahara, H.4
Stone, S.5
Peters, G.6
-
22
-
-
0029917511
-
The helix-loop-helix protein 1d-1 and a retinoblastoma protein binding mutant of SV40 T antigen synergize to reactivate DNA synthesis in senescent human fibroblasts
-
Hara, E., Uzman, J.A., Dimri, G.P., Nehlin, J.O., Testori, A. and Campisi, J. (1996b) The helix-loop-helix protein 1d-1 and a retinoblastoma protein binding mutant of SV40 T antigen synergize to reactivate DNA synthesis in senescent human fibroblasts. Dev. Genet., 18, 161-172.
-
(1996)
Dev. Genet.
, vol.18
, pp. 161-172
-
-
Hara, E.1
Uzman, J.A.2
Dimri, G.P.3
Nehlin, J.O.4
Testori, A.5
Campisi, J.6
-
23
-
-
0025279931
-
Telomeres shorten during aging of human fibroblasts
-
Harley, C.B., Futcher, A.B. and Greider, C.W. (1990) Telomeres shorten during aging of human fibroblasts. Nature, 345, 458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
24
-
-
0035870124
-
Effects of simian virus 40 T-antigens on normal human mammary epithelial cells reveal evidence for spontaneous alterations in addition to loss of p16(INK4a) expression
-
Huschtscha, L.I., Neumann, A.A., Noble, J.R. and Reddel, R.R. (2001) Effects of simian virus 40 T-antigens on normal human mammary epithelial cells reveal evidence for spontaneous alterations in addition to loss of p16(INK4a) expression. Exp. Cell Res., 265, 125-134.
-
(2001)
Exp. Cell Res.
, vol.265
, pp. 125-134
-
-
Huschtscha, L.I.1
Neumann, A.A.2
Noble, J.R.3
Reddel, R.R.4
-
25
-
-
0020581752
-
Reinitiation of host DNA synthesis in senescent human diploid cells by infection with simian virus 40
-
Ide, T., Tsuji, Y., Ishibashi, S. and Mitsui, Y. (1983) Reinitiation of host DNA synthesis in senescent human diploid cells by infection with simian virus 40. Exp. Cell Res., 143, 343-349.
-
(1983)
Exp. Cell Res.
, vol.143
, pp. 343-349
-
-
Ide, T.1
Tsuji, Y.2
Ishibashi, S.3
Mitsui, Y.4
-
26
-
-
0034832956
-
Regulation of cellular senescence by p53
-
Itahana, K., Dimri, G. and Campisi, J. (2001) Regulation of cellular senescence by p53. Eur. J. Biochem., 268, 2784-2791.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 2784-2791
-
-
Itahana, K.1
Dimri, G.2
Campisi, J.3
-
27
-
-
0037214382
-
Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1
-
Itahana, K. et al. (2003) Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1. Mol. Cell. Biol., 23, 389-401.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 389-401
-
-
Itahana, K.1
-
28
-
-
0032727616
-
TIN2, a new regulator of telomere length in human cells
-
Kim, S.H., Kaminker, P. and Campisi, J. (1999) TIN2, a new regulator of telomere length in human cells. Nat. Genet., 23, 405-412.
-
(1999)
Nat. Genet.
, vol.23
, pp. 405-412
-
-
Kim, S.H.1
Kaminker, P.2
Campisi, J.3
-
29
-
-
0037148342
-
Telomeres, cancer and aging: In search of a happy ending
-
Kim, S.H., Kaminker, P.G. and Campisi, J. (2002) Telomeres, cancer and aging: in search of a happy ending. Oncogene, 21, 503-511.
-
(2002)
Oncogene
, vol.21
, pp. 503-511
-
-
Kim, S.H.1
Kaminker, P.G.2
Campisi, J.3
-
30
-
-
0032487675
-
Both Rb/p16LNK4a inactivation and telomerase activity are required to immortalize human epithelial cells
-
Kiyono, T., Foster, S.A., Koop, J.I., McDougall, J.K., Galloway, D.A. and Klingelhutz, A.J. (1998) Both Rb/p16LNK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature, 396, 84-88.
-
(1998)
Nature
, vol.396
, pp. 84-88
-
-
Kiyono, T.1
Foster, S.A.2
Koop, J.I.3
McDougall, J.K.4
Galloway, D.A.5
Klingelhutz, A.J.6
-
31
-
-
0020520516
-
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
-
Land, H., Parada, L.F. and Weinberg, R.A. (1983) Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature, 304, 596-602.
-
(1983)
Nature
, vol.304
, pp. 596-602
-
-
Land, H.1
Parada, L.F.2
Weinberg, R.A.3
-
32
-
-
0022765867
-
Mitogenic effects of the proto-oncogene and oncogene forms of c-H-ras DNA in human diploid fibroblasts
-
Lumpkin, C.K., Knepper, J.E., Butel, J.S., Smith, J.R. and Pereira-Smith, O.M. (1986) Mitogenic effects of the proto-oncogene and oncogene forms of c-H-ras DNA in human diploid fibroblasts. Mol. Cell. Biol., 6, 2990-2993.
-
(1986)
Mol. Cell. Biol.
, vol.6
, pp. 2990-2993
-
-
Lumpkin, C.K.1
Knepper, J.E.2
Butel, J.S.3
Smith, J.R.4
Pereira-Smith, O.M.5
-
33
-
-
0032510327
-
Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts
-
McConnell, B.B., Starborg, M., Brookes, S. and Peters, G. (1998) Inhibitors of cyclin- dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts. Curr. Biol., 8, 351-354.
-
(1998)
Curr. Biol.
, vol.8
, pp. 351-354
-
-
McConnell, B.B.1
Starborg, M.2
Brookes, S.3
Peters, G.4
-
34
-
-
0029993858
-
Efficient transfer, integration and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
-
Naldini, L., Blomer, U., Gage, F.H., Trono, D. and Verma, I.M. (1996) Efficient transfer, integration and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc. Natl Acad. Sci. USA, 93, 11382-11388.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11382-11388
-
-
Naldini, L.1
Blomer, U.2
Gage, F.H.3
Trono, D.4
Verma, I.M.5
-
35
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita, M., Nunez, S., Heard, E., Narita, M., Lin, A.W., Hearn, S.A., Spector, D.L., Hannon, G.J. and Lowe, S.W. (2003) Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell, 113, 703-716.
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
Narita, M.4
Lin, A.W.5
Hearn, S.A.6
Spector, D.L.7
Hannon, G.J.8
Lowe, S.W.9
-
36
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
Paddison, P.J., Caudy, A.A., Bernstein, E., Hannon, G.J. and Conklin, D.S. (2002) Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells, Genes Dev., 16, 948-958.
-
(2002)
Genes Dev.
, vol.16
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
Hannon, G.J.4
Conklin, D.S.5
-
37
-
-
0035114576
-
Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions
-
Ramirez, R.D., Morales, C.P., Herbert, B.S., Rohde, J.M., Passons, C., Shay, J.W. and Wright, W.E. (2001) Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions. Genes Dev., 15, 398-403.
-
(2001)
Genes Dev.
, vol.15
, pp. 398-403
-
-
Ramirez, R.D.1
Morales, C.P.2
Herbert, B.S.3
Rohde, J.M.4
Passons, C.5
Shay, J.W.6
Wright, W.E.7
-
38
-
-
0034012226
-
The role of senescence and immortalization in carcinogenesis
-
Reddel, R.R. (2000) The role of senescence and immortalization in carcinogenesis. Carcinogen, 21, 477-484.
-
(2000)
Carcinogen
, vol.21
, pp. 477-484
-
-
Reddel, R.R.1
-
39
-
-
0036288508
-
A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status
-
Rheinwald, J.G. et al. (2002) A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status. Mol. Cell. Biol., 22, 5157-5172.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5157-5172
-
-
Rheinwald, J.G.1
-
40
-
-
0035252089
-
Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
-
Romanov, S.R., Kozakiewicz, B.K., Holst, C.R., Stampfer, M.R., Haupt, L.M. and Tlsty, T.D. (2001) Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature, 409, 633-637.
-
(2001)
Nature
, vol.409
, pp. 633-637
-
-
Romanov, S.R.1
Kozakiewicz, B.K.2
Holst, C.R.3
Stampfer, M.R.4
Haupt, L.M.5
Tlsty, T.D.6
-
41
-
-
0027249703
-
Relative mitogenic activities of wild-type and retinoblastoma binding defective SV40 T antigens in serum deprived and senescent human fibroblasts
-
Sakamoto, K., Howard, T., Ogryzko, V., Xu, N.Z., Corsico, C.C., Jones, D.H. and Howard, B. (1993) Relative mitogenic activities of wild-type and retinoblastoma binding defective SV40 T antigens in serum deprived and senescent human fibroblasts. Oncogene, 8, 1887-1893.
-
(1993)
Oncogene
, vol.8
, pp. 1887-1893
-
-
Sakamoto, K.1
Howard, T.2
Ogryzko, V.3
Xu, N.Z.4
Corsico, C.C.5
Jones, D.H.6
Howard, B.7
-
42
-
-
0037013154
-
A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy
-
Schmitt, C.A., Fridman, J.S., Yang, M., Lee, S., Baranov, E., Hoffman, R.M. and Lowe, S.W. (2002) A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy. Cell, 109, 335-346.
-
(2002)
Cell
, vol.109
, pp. 335-346
-
-
Schmitt, C.A.1
Fridman, J.S.2
Yang, M.3
Lee, S.4
Baranov, E.5
Hoffman, R.M.6
Lowe, S.W.7
-
44
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano, M., Lin, A.W., McCurrach, M.E., Beach, D. and Lowe, S.W. (1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell, 88, 593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
45
-
-
0035221480
-
Aging and cancer: The telomere and telomerase connection
-
Shay, J.W. and Wright, W.E. (2001) Aging and cancer: the telomere and telomerase connection. Novartis Found. Symp., 235, 116-125.
-
(2001)
Novartis Found. Symp.
, vol.235
, pp. 116-125
-
-
Shay, J.W.1
Wright, W.E.2
-
46
-
-
0026054961
-
A role for both Rb and p53 in the regulation of human cellular senescence
-
Shay, J.W., Pereira-Smith, O.M. and Wright, W.E. (1991) A role for both Rb and p53 in the regulation of human cellular senescence. Exp. Cell Res., 196, 33-39.
-
(1991)
Exp. Cell Res.
, vol.196
, pp. 33-39
-
-
Shay, J.W.1
Pereira-Smith, O.M.2
Wright, W.E.3
-
47
-
-
0027496456
-
The frequency of immortalization of human fibroblasts and mammary epithelial cells transfected with SV40 large T-antigen
-
Shay, J.W., Van Der Haegen, B.A., Ying, Y. and Wright, W.E. (1993) The frequency of immortalization of human fibroblasts and mammary epithelial cells transfected with SV40 large T-antigen. Exp. Cell Res., 209, 45-52.
-
(1993)
Exp. Cell Res.
, vol.209
, pp. 45-52
-
-
Shay, J.W.1
Van Der Haegen, B.A.2
Ying, Y.3
Wright, W.E.4
-
48
-
-
0034682721
-
Cellular senescence: Mitotic clock or culture shock?
-
Sherr, C.J. and DePinho, R.A. (2000) Cellular senescence: Mitotic clock or culture shock? Cell, 102, 407-410.
-
(2000)
Cell
, vol.102
, pp. 407-410
-
-
Sherr, C.J.1
DePinho, R.A.2
-
50
-
-
0020132123
-
Isolation of a transforming sequence from a human bladder carcinoma cell line
-
Shih, C. and Weinberg, R.A. (1982) Isolation of a transforming sequence from a human bladder carcinoma cell line. Cell, 29, 161-169.
-
(1982)
Cell
, vol.29
, pp. 161-169
-
-
Shih, C.1
Weinberg, R.A.2
-
51
-
-
0006312841
-
Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene
-
Stampfer, M.R. and Bartley, J.C. (1985) Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene. Proc. Natl Acad. Sci. USA, 82, 2394-2398.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 2394-2398
-
-
Stampfer, M.R.1
Bartley, J.C.2
-
52
-
-
0033013980
-
Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts
-
Stein, G. H., Drullinger, L.F., Soulard, A. and Dulic, V. (1999) Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts. Mol. Cell. Biol., 19, 2109-2117.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2109-2117
-
-
Stein, G.H.1
Drullinger, L.F.2
Soulard, A.3
Dulic, V.4
-
53
-
-
0037086268
-
DNA damage is able to induce senescence in tumor cells in vitro and in vivo
-
te Poele, R.H., Okorokov, A.L., Jardine, L., Cummings, J. and Joel, S.P. (2002) DNA damage is able to induce senescence in tumor cells in vitro and in vivo. Cancer Res., 62, 1876-1883.
-
(2002)
Cancer Res.
, vol.62
, pp. 1876-1883
-
-
Te Poele, R.H.1
Okorokov, A.L.2
Jardine, L.3
Cummings, J.4
Joel, S.P.5
-
54
-
-
0032567967
-
Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
-
Vaziri, H. and Benchimol, S. (1998) Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span. Curr. Biol., 8, 279-282.
-
(1998)
Curr. Biol.
, vol.8
, pp. 279-282
-
-
Vaziri, H.1
Benchimol, S.2
-
55
-
-
0033572894
-
Differentiation between senescence (MI) and crisis (M2) in human fibroblast cultures
-
Wei, W. and Sedivy, J. M. (1999) Differentiation between senescence (MI) and crisis (M2) in human fibroblast cultures. Exp. Cell Res., 253, 519-522.
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 519-522
-
-
Wei, W.1
Sedivy, J.M.2
-
56
-
-
0027509950
-
Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase
-
Wellinger, R.J., Wolf, A.J. and Zakian, V.A. (1993) Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase. Cell, 72, 51-60.
-
(1993)
Cell
, vol.72
, pp. 51-60
-
-
Wellinger, R.J.1
Wolf, A.J.2
Zakian, V.A.3
-
57
-
-
0028978274
-
A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma
-
Wolfel, T. et al, (1995) A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma. Science, 269, 1281-1284.
-
(1995)
Science
, vol.269
, pp. 1281-1284
-
-
Wolfel, T.1
-
58
-
-
0033834247
-
Telomere dynamics in cancer progression and prevention: Fundamental differences in human and mouse telomere biology
-
Wright, W.E. and Shay, J.W. (2000) Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology. Nat. Med., 6, 849-851.
-
(2000)
Nat. Med.
, vol.6
, pp. 849-851
-
-
Wright, W.E.1
Shay, J.W.2
-
59
-
-
0035253719
-
Cellular senescence as a tumor-protection mechanism: The essential role of counting
-
Wright, W.E. and Shay, J.W. (2001) Cellular senescence as a tumor-protection mechanism: The essential role of counting. Curr. Opin. Genet. Dev., 11, 98-103.
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 98-103
-
-
Wright, W.E.1
Shay, J.W.2
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