Biosynthetic engineering of polyketide synthases

Expert Opinion on Therapeutic Patents

Volumn 13, Issue 10, 2003, Pages 1579-1606

  Wilkinson, Barrie ^a   Kendrew, Steven G ^a   Sheridan, Rose M ^a   Leadlay, Peter F ^a  

^a BIOTICA TECHNOLOGY LTD   (United Kingdom)

Author keywords

Biosynthetic engineering; Combinatorial biosynthesis; Macrolide; Polyketide; Polyketide synthase (PKS)

Indexed keywords

AMPHOTERICIN; ANSAMITOCIN; ASCOMYCIN; AVERMECTIN DERIVATIVE; BLEOMYCIN; EPOTHILONE DERIVATIVE; ERYTHROMYCIN; ERYTHROMYCIN DERIVATIVE; GELDANAMYCIN; LANKAMYCIN; LEINAMYCIN; MEGALOMICIN; METHYMYCIN; MIDECAMYCIN; MONENSIN; MYCINAMICIN; NATAMYCIN; NIDDAMYCIN; NYSTATIN; OLEANDOMYCIN; PIKROMYCIN; POLYKETIDE; POLYKETIDE SYNTHASE; RAPAMYCIN; RAPAMYCIN DERIVATIVE; RIFAMYCIN; SPIRAMYCIN; TACROLIMUS; TYLOSIN; UNINDEXED DRUG;

ACYLATION; ALKYLATION; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; BIOTECHNOLOGY; DRUG SPECIFICITY; DRUG SYNTHESIS; ESCHERICHIA COLI; GENETIC CODE; GLYCOSYLATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; ONCHOCERCA VOLVULUS; OXIDATION REDUCTION REACTION; PATENT; PHARMACEUTICAL ENGINEERING; PSEUDOMONAS; REVIEW; SACCHAROPOLYSPORA; STAPHYLOCOCCUS AUREUS; STREPTOMYCES COELICOLOR; STREPTOMYCES HYGROSCOPICUS;

EID: 0242551258     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.13.10.1579     Document Type: Review

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