-
1
-
-
0027382486
-
Polyketide synthesis: Prospects for hybrid antibiotics
-
KATZ, L. & S. DONADIO: Polyketide synthesis: Prospects for hybrid antibiotics. Ann. Rev. Microbiol. 47: 875-912, 1993
-
(1993)
Ann. Rev. Microbiol.
, vol.47
, pp. 875-912
-
-
Katz, L.1
Donadio, S.2
-
2
-
-
0001747786
-
Genetic contributions to understanding polyketide synthases
-
HOPWOOD, D.: Genetic contributions to understanding polyketide synthases. Chem. Rev. 97: 2465-2497, 1997
-
(1997)
Chem. Rev.
, vol.97
, pp. 2465-2497
-
-
Hopwood, D.1
-
3
-
-
0028044628
-
Characterisation of a Streptomyces antibioticus gene encoding a type I polyketide synthase which has an unusual coding sequence
-
SWAN, D. G.; A. M. RODRIGUEZ, C. VILCHES, C. MENDEZ & J. A. SALAS: Characterisation of a Streptomyces antibioticus gene encoding a type I polyketide synthase which has an unusual coding sequence. Mol. Gen. Genet. 242: 358-362, 1994
-
(1994)
Mol. Gen. Genet.
, vol.242
, pp. 358-362
-
-
Swan, D.G.1
Rodriguez, A.M.2
Vilches, C.3
Mendez, C.4
Salas, J.A.5
-
4
-
-
0028910531
-
A cytochrome P450-like gene possibly involved in oleandomycin biosynthesis by Streptomyces antibioticus
-
RODRIGUEZ, A. M.; C. OLANO, C. MENDEZ & C. R. HUTCHINSON: A cytochrome P450-like gene possibly involved in oleandomycin biosynthesis by Streptomyces antibioticus. FEMS Microbiol. Lett. 127: 117-120, 1995
-
(1995)
FEMS Microbiol. Lett.
, vol.127
, pp. 117-120
-
-
Rodriguez, A.M.1
Olano, C.2
Mendez, C.3
Hutchinson, C.R.4
-
5
-
-
0031663470
-
Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring
-
OLANO, C.; A. M. RODRIGUEZ, J. M. MICHEL, C. MENDEZ, M. C. RAYNAL & J. A. SALAS: Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring. Mol. Gen. Genet. 259: 299-308, 1998
-
(1998)
Mol. Gen. Genet.
, vol.259
, pp. 299-308
-
-
Olano, C.1
Rodriguez, A.M.2
Michel, J.M.3
Mendez, C.4
Raynal, M.C.5
Salas, J.A.6
-
6
-
-
0031799094
-
Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus
-
QUIROS, L. M.; I. AGUIRREZABALAGA, C. OLANO, C. MENDEZ & J. A. SALAS: Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus. Mol. Microbiol. 28: 1177-1185, 1998
-
(1998)
Mol. Microbiol.
, vol.28
, pp. 1177-1185
-
-
Quiros, L.M.1
Aguirrezabalaga, I.2
Olano, C.3
Mendez, C.4
Salas, J.A.5
-
7
-
-
0034141564
-
Formation of functional heterologous complexes using subunits from the picromycin, erythromycin, and oleandomycin polyketide synthases
-
TANG, L.; H. FU & R. MCDANIEL: Formation of functional heterologous complexes using subunits from the picromycin, erythromycin, and oleandomycin polyketide synthases. Chem. & Biol. 7: 77-84, 2000
-
(2000)
Chem. & Biol.
, vol.7
, pp. 77-84
-
-
Tang, L.1
Fu, H.2
Mcdaniel, R.3
-
8
-
-
0032921036
-
Recombinant polyketide synthesis in Streptomyces: Engineering of improved host strains
-
ZIERMANN, R. & M. C. BETLACH: Recombinant polyketide synthesis in Streptomyces: Engineering of improved host strains. Biotechniques 26: 106-110, 1999
-
(1999)
Biotechniques
, vol.26
, pp. 106-110
-
-
Ziermann, R.1
Betlach, M.C.2
-
9
-
-
0003728297
-
-
The John Innes Foundation, Norwich, UK
-
HOPWOOD, D. A.; M. J. BIBB, K. F. CHATER, T. KIESER, C. J. BRUTON, H. M. KIESER, D. J. LYDIATE, C. P. SMITH, J. M. WARD & H. SCHREMPF: Genetic Manipulation of Streptomyces: A Laboratory Manual. The John Innes Foundation, Norwich, UK, 1985
-
(1985)
Genetic Manipulation of Streptomyces: A Laboratory Manual
-
-
Hopwood, D.A.1
Bibb, M.J.2
Chater, K.F.3
Kieser, T.4
Bruton, C.J.5
Kieser, H.M.6
Lydiate, D.J.7
Smith, C.P.8
Ward, J.M.9
Schrempf, H.10
-
11
-
-
0033515090
-
Multiple genetic modifications of the erythromycin gene cluster to produce a library of novel "unnatural" natural products
-
MCDANIEL, R.; A. THAMCHAIPENET, C. GUSTAFSSON, H. FU, M. BETLACH, M. BETLACH & G. ASHLEY: Multiple genetic modifications of the erythromycin gene cluster to produce a library of novel "unnatural" natural products. Proc. Natl. Acad. Sci. USA 96: 1846-1851, 1999
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1846-1851
-
-
Mcdaniel, R.1
Thamchaipenet, A.2
Gustafsson, C.3
Fu, H.4
Betlach, M.5
Betlach, M.6
Ashley, G.7
-
12
-
-
0033533388
-
Conversion of a β-ketoacyl synthase to a malonyl decarboxylase by replacement of the active-site cysteine with glutamine
-
WITKOWSKI, A.; A. K. JOSHI, Y. LINDQVIST & S. SMITH: Conversion of a β-ketoacyl synthase to a malonyl decarboxylase by replacement of the active-site cysteine with glutamine. Biochemistry 38: 11643-11650, 1999
-
(1999)
Biochemistry
, vol.38
, pp. 11643-11650
-
-
Witkowski, A.1
Joshi, A.K.2
Lindqvist, Y.3
Smith, S.4
-
13
-
-
0033619244
-
A chain initiation factor common to both modular and aromatic polyketide synthases
-
BISANG, C.; P. F. LONG, J. CORTÉS, J. WESTCOTT, J. CROSBY, A.-L. MATHARU, R. J. COX, T. J. SIMPSON, J. STAUNTON & P. F. LEADLAY: A chain initiation factor common to both modular and aromatic polyketide synthases. Nature 401: 502-505, 1999
-
(1999)
Nature
, vol.401
, pp. 502-505
-
-
Bisang, C.1
Long, P.F.2
Cortés, J.3
Westcott, J.4
Crosby, J.5
Matharu, A.-L.6
Cox, R.J.7
Simpson, T.J.8
Staunton, J.9
Leadlay, P.F.10
-
14
-
-
0027932534
-
Engineered biosynthesis of a complete macrolactone in a heterologous host
-
KAO, C. M.; L. KATZ & C. KHOSLA: Engineered biosynthesis of a complete macrolactone in a heterologous host. Science 265: 509-512, 1994
-
(1994)
Science
, vol.265
, pp. 509-512
-
-
Kao, C.M.1
Katz, L.2
Khosla, C.3
-
15
-
-
0033178656
-
Elucidating the mechanism of chain termination switching in the picromycin/methymycin polyketide synthase
-
TANG, L.; H. FU, M. C. BETLACH & R. MCDANIEL: Elucidating the mechanism of chain termination switching in the picromycin/methymycin polyketide synthase. Chem. & Biol. 6: 553-558, 1999
-
(1999)
Chem. & Biol.
, vol.6
, pp. 553-558
-
-
Tang, L.1
Fu, H.2
Betlach, M.C.3
Mcdaniel, R.4
-
16
-
-
0025859219
-
An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraea
-
WEBER, J. M.; J. O. LEUNG, S. J. SWANSON, K. B. IDLER & J. B. MCALPINE: An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraea. Science 252: 114-117, 1991
-
(1991)
Science
, vol.252
, pp. 114-117
-
-
Weber, J.M.1
Leung, J.O.2
Swanson, S.J.3
Idler, K.B.4
Mcalpine, J.B.5
-
17
-
-
0025999536
-
Cloning and sequence analysis of the genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea; sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases
-
HAYDOCK, S. F.; J. A. DOWSON, N. DHILLON, G. A. ROBERTS, J. CORTES & P. F. LEADLAY: Cloning and sequence analysis of the genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea; sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases. Mol. Gen. Genet. 230: 120-128, 1991
-
(1991)
Mol. Gen. Genet.
, vol.230
, pp. 120-128
-
-
Haydock, S.F.1
Dowson, J.A.2
Dhillon, N.3
Roberts, G.A.4
Cortes, J.5
Leadlay, P.F.6
-
18
-
-
0027455631
-
Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis
-
STASSI, D.; S. DONADIO, M. J. STAVER & L. KATZ: Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis. J. Bacteriol. 175: 182-189, 1993
-
(1993)
J. Bacteriol.
, vol.175
, pp. 182-189
-
-
Stassi, D.1
Donadio, S.2
Staver, M.J.3
Katz, L.4
-
19
-
-
0032552963
-
Characterization of the macrolide P-450 hydroxylase from Streptomyces venezuelae which converts narbomycin to picromycin
-
BETLACH, M. C.; J. T. KEALEY, M. C. BETLACH, G. A. ASHLEY & R. MCDANIEL: Characterization of the macrolide P-450 hydroxylase from Streptomyces venezuelae which converts narbomycin to picromycin. Biochemistry 37: 14937-14942, 1998
-
(1998)
Biochemistry
, vol.37
, pp. 14937-14942
-
-
Betlach, M.C.1
Kealey, J.T.2
Betlach, M.C.3
Ashley, G.A.4
Mcdaniel, R.5
-
20
-
-
0032213230
-
Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae
-
XUE, Y.; D. WILSON, L. ZHAO, H.-W. LIU & D. H. SHERMAN: Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae. Chem. & Biol. 5: 661-667, 1998
-
(1998)
Chem. & Biol.
, vol.5
, pp. 661-667
-
-
Xue, Y.1
Wilson, D.2
Zhao, L.3
Liu, H.-W.4
Sherman, D.H.5
-
21
-
-
0028236752
-
Analysis of five tylosin biosynthetic genes from the tylIBA region of the Streptomyces fradiae genome
-
MERSON-DAVIES, L. A. & E. CUNDLIFFE: Analysis of five tylosin biosynthetic genes from the tylIBA region of the Streptomyces fradiae genome. Mol. Microbiol. 13: 349-355, 1994
-
(1994)
Mol. Microbiol.
, vol.13
, pp. 349-355
-
-
Merson-Davies, L.A.1
Cundliffe, E.2
-
22
-
-
0020574429
-
Biological conversion of erythronolide B, an intermediate of erythromycin biogenesis, into new "hybrid" macrolide antibiotics
-
SPAGNOLI, R. & L. CAPPELLETTI: Biological conversion of erythronolide B, an intermediate of erythromycin biogenesis, into new "hybrid" macrolide antibiotics. J. Antibiotics 36: 365-375, 1983
-
(1983)
J. Antibiotics
, vol.36
, pp. 365-375
-
-
Spagnoli, R.1
Cappelletti, L.2
-
23
-
-
0025346054
-
Biosynthetic studies on oleandomycin by incorporation of the chemically synthesized aglycones
-
TATSUTA, K.; H. GUNJI, S. TAJIMA, T. ISHIYAMA, S. IMAI, S. OKUYAMA & S. FUKATSU: Biosynthetic studies on oleandomycin by incorporation of the chemically synthesized aglycones. J. Antibiotics 43: 909-911, 1990
-
(1990)
J. Antibiotics
, vol.43
, pp. 909-911
-
-
Tatsuta, K.1
Gunji, H.2
Tajima, S.3
Ishiyama, T.4
Imai, S.5
Okuyama, S.6
Fukatsu, S.7
-
24
-
-
0028072875
-
Characterization and expression of a P450-like mycinamicin biosynthesis gene using a novel Micromonospora-Escherichia coli shuttle cosmid vector
-
INOUYE, M.; Y. TAKADA, N. MUTO, T. BEPPU & S. HORINOUCHI: Characterization and expression of a P450-like mycinamicin biosynthesis gene using a novel Micromonospora-Escherichia coli shuttle cosmid vector. Mol. Gen. Genet. 245: 456-464, 1994
-
(1994)
Mol. Gen. Genet.
, vol.245
, pp. 456-464
-
-
Inouye, M.1
Takada, Y.2
Muto, N.3
Beppu, T.4
Horinouchi, S.5
-
25
-
-
0027248795
-
Two-step epoxidation of hyoscyamine to scopolamine is catalyzed by bifunctional hyoscyamine 6 beta-hydroxylase
-
HASHIMOTO, T.; J. MATSUDA & Y. YAMADA: Two-step epoxidation of hyoscyamine to scopolamine is catalyzed by bifunctional hyoscyamine 6 beta-hydroxylase. FEBS Lett. 329: 35-39, 1993
-
(1993)
FEBS Lett.
, vol.329
, pp. 35-39
-
-
Hashimoto, T.1
Matsuda, J.2
Yamada, Y.3
-
26
-
-
0023654599
-
Purification and characterization of hyoscyamine 6 beta-hydroxylase from root cultures of Hyoscyamine niger L. Hydroxylase and epoxidase activities in the enzyme preparation
-
HASHIMOTO, T. & Y. YAMADA: Purification and characterization of hyoscyamine 6 beta-hydroxylase from root cultures of Hyoscyamine niger L. Hydroxylase and epoxidase activities in the enzyme preparation. Eur. J. Biochem. 164: 277-285, 1987
-
(1987)
Eur. J. Biochem.
, vol.164
, pp. 277-285
-
-
Hashimoto, T.1
Yamada, Y.2
|