The barbamide biosynthetic gene cluster: A novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit

Gene

Volumn 296, Issue 1-2, 2002, Pages 235-247

  Chang, Zunxue ^a   Flatt, Patricia ^b   Gerwick, William H ^b   Nguyen, Viet Anh ^c   Willis, Christine L ^c   Sherman, David H ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b OREGON STATE UNIVERSITY   (United States)

^c UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Halogenase; Lyngbya majuscula; Modular polyketide synthase; Natural product biosynthesis; Non ribosomal peptide synthetase

Indexed keywords

ACETIC ACID; ADENOSINE TRIPHOSPHATE DERIVATIVE; AMINO ACID; BARBAMIDE; CYSTEINE; LEUCINE; LIPOPEPTIDE; NON RIBOSOMAL PEPTIDE SYNTHETASE; PEPTIDE SYNTHASE; PHENYLALANINE; POLYKETIDE SYNTHASE; THIAZOLE DERIVATIVE; TRICHLOROLEUCINE; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; BACTERIAL DNA; DRUG DERIVATIVE; MULTIENZYME COMPLEX;

ADENYLATION; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BIOSYNTHESIS; CHLORINATION; CONTROLLED STUDY; COSMID; DNA SEQUENCE; DRUG ISOLATION; GENE CLUSTER; GENETIC ANALYSIS; GENETIC VARIABILITY; LYNGBYA MAJUSCULA; MOLECULAR CLONING; NONHUMAN; OPEN READING FRAME; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; AMINO ACID SEQUENCE; BINDING SITE; CHEMISTRY; CYANOBACTERIUM; GENE LIBRARY; GENE ORDER; GENETICS; METABOLISM; MOLECULAR GENETICS; MULTIGENE FAMILY; SEQUENCE HOMOLOGY;

CYANOBACTERIA; LYNGBYA; LYNGBYA MAJUSCULA;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; BINDING SITES; CYANOBACTERIA; DNA, BACTERIAL; GENE ORDER; GENES, BACTERIAL; GENOMIC LIBRARY; LEUCINE; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MULTIGENE FAMILY; PEPTIDE SYNTHASES; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; THIAZOLES;

EID: 0037151788     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(02)00860-0     Document Type: Article

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