Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units

Biochemistry

Volumn 38, Issue 5, 1999, Pages 1643-1651

  Lau, Janice ^a   Fu, Hong ^b   Cane, David E ^c   Khosla, Chaitan ^a,d  

^a Stanford University   (United States)

^b KOSAN BIOSCIENCES INC   (United States)

^c BROWN UNIVERSITY   (United States)

^d STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; POLYKETIDE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHIRALITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBUNIT; ISOMERISM; MUTAGENESIS; POLYMERIZATION; PRIORITY JOURNAL; STEREOCHEMISTRY;

ACYL COENZYME A; ACYLTRANSFERASES; AMINO ACID SEQUENCE; ERYTHROMYCIN; ESCHERICHIA COLI; ISOENZYMES; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; PLASMIDS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SIROLIMUS; STEREOISOMERISM; STREPTOMYCES; SUBSTRATE SPECIFICITY; THIOLESTER HYDROLASES;

EID: 0033514424     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9820311     Document Type: Article

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