Desoxyepothilone B is curative against human tumor xenografts that are refractory to paclitaxel

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 26, 1998, Pages 15798-15802

  Chou, Ting Chao ^a,b   Zhang, Xiu Guo ^a   Harris, Christina R ^a   Kuduk, Scott D ^a   Balog, Aaron ^a,c   Savin, Kenneth A ^a,d   Bertino, Joseph R ^a,b   Danishefsky, Samuel J ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

^c BRISTOL MYERS SQUIBB   (United States)

^d ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DESOXYEPOTHILONE B; DOXORUBICIN; EPOTHILONE B; EPOTHILONE D; ETOPOSIDE; MACROLIDE; PACLITAXEL; UNCLASSIFIED DRUG; VINBLASTINE;

ARTICLE; BREAST ADENOCARCINOMA; CANCER; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MICROTUBULE ASSEMBLY; MITOSIS INHIBITION; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL SURVIVAL; DRUG RESISTANCE, NEOPLASM; EPOTHILONES; FEMALE; HUMANS; LACTONES; LEUKEMIA P388; LEUKEMIA, T-CELL, ACUTE; MICE; MICE, NUDE; OVARIAN NEOPLASMS; PACLITAXEL; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0032416734     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.26.15798     Document Type: Article

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