Lovastatin biosynthesis in Aspergillus terreus: Characterization of blocked mutants, enzyme activities and a multifunctional polyketide synthase gene

Chemistry and Biology

Volumn 6, Issue 7, 1999, Pages 429-439

  Hendrickson, Lee ^a   Davis, C Ray ^b   Roach, Claudia ^c   Nguyen, Di Kim ^c   Aldrich, Teri ^b   McAda, Phyllis C ^d   Reeves, Christopher D ^e  

^a ELI LILLY AND COMPANY   (United States)

^b AMGEN INC   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d MDS Inc   (Canada)

^e KOSAN BIOSCIENCES INC   (United States)

Author keywords

C methylation; Fatty acid synthase; Multifunctional enzyme; Peptide synthetase; Polyketide synthase

Indexed keywords

BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CERULENIN; CYCLIZATION; ENZYME ACTIVITY; ENZYME INHIBITOR; ENZYME STRUCTURE; FUNGAL MUTANT; GENE ISOLATION; GENE MUTATION; HEXAHYDRONAPHTHALENE; METHYLTRANSFERASE; MEVINOLIN; POLYKETIDE SYNTHASE;

ASPERGILLUS TERREUS;

EID: 0033168682     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(99)80061-1     Document Type: Article

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