Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: Analysis of the gene cluster and deduction of the biosynthetic pathway

Chemistry and Biology

Volumn 7, Issue 6, 2000, Pages 395-403

  Brautaset, Trygve ^a   Sekurova, Olga N ^a   Sletta, Håvard ^b   Ellingsen, Trond E ^b   Strøm, Arne R ^a   Valla, Svein ^a   Zotchev, Sergey B ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b SINTEF   (Norway)

Author keywords

Gene cluster; Polyene antibiotic; Polyketide synthase

Indexed keywords

ANTIBIOTIC PRODUCTION; ANTIFUNGAL AGENT; BACTERIAL GENOME; BIOCHEMICAL PATHWAY; BIOSYNTHESIS; DNA DETERMINATION; GENE CLUSTER; GENE DISRUPTION; GENE PRODUCT; GENETIC IMPROVEMENT; MOLECULAR CLONING; MYCOSAMINE; NUCLEOTIDE SEQUENCE; NYSTATIN; POLYKETIDE SYNTHASE; THIOL ESTER HYDROLASE;

BACTERIA (MICROORGANISMS); STREPTOMYCES NOURSEI;

EID: 0034047123     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(00)00120-4     Document Type: Article

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