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Volumn 249, Issue 1-2, 2000, Pages 153-160

Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosum

Author keywords

Myxobacteria; Non ribosomal peptide synthetase; P450 enzyme; Polyketide; Polyketide synthase

Indexed keywords

CYTOCHROME P450; EPOTHILONE A; EPOTHILONE B; PEPTIDE SYNTHASE; POLYKETIDE SYNTHASE;

EID: 0034673927     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(00)00149-9     Document Type: Article
Times cited : (156)

References (29)
  • 3
    • 0027530376 scopus 로고
    • Determination of monensins A and B in the fermentation broth of Streptomyces cinnamonensis by high performance liquid chromotography
    • Beran M., Zima J. Determination of monensins A and B in the fermentation broth of Streptomyces cinnamonensis by high performance liquid chromotography. Chromatographia. 35:1993;206-208.
    • (1993) Chromatographia , vol.35 , pp. 206-208
    • Beran, M.1    Zima, J.2
  • 4
    • 0026645203 scopus 로고
    • Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp
    • Bierman M., Logan R., O'Brien K., Seno E.T., Rao R.N., Schoner B.E. Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp. Gene. 116:1992;43-49.
    • (1992) Gene , vol.116 , pp. 43-49
    • Bierman, M.1    Logan, R.2    O'Brien, K.3    Seno, E.T.4    Rao, R.N.5    Schoner, B.E.6
  • 7
    • 0040424324 scopus 로고
    • Overproduction of bacterial chaperones improves the solubility of recombinant protein tyrosine kinases in Escherichia coli
    • Caspers P., Stieger M., Burn P. Overproduction of bacterial chaperones improves the solubility of recombinant protein tyrosine kinases in Escherichia coli. Cell. Mol. Biol. 40:1994;635-644.
    • (1994) Cell. Mol. Biol. , vol.40 , pp. 635-644
    • Caspers, P.1    Stieger, M.2    Burn, P.3
  • 8
    • 0025081416 scopus 로고
    • An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea
    • Cortes J., Haydock S.F., Roberts G.A., Bevitt D.J., Leadlay P.F. An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea. Nature. 348:1990;176-178.
    • (1990) Nature , vol.348 , pp. 176-178
    • Cortes, J.1    Haydock, S.F.2    Roberts, G.A.3    Bevitt, D.J.4    Leadlay, P.F.5
  • 9
    • 0026415106 scopus 로고
    • Modular organization of genes required for complex polyketide biosynthesis
    • Donadio S., Staver M.J., McAlpine J.B., Swanson S.J., Katz L. Modular organization of genes required for complex polyketide biosynthesis. Science. 252:1991;675-679.
    • (1991) Science , vol.252 , pp. 675-679
    • Donadio, S.1    Staver, M.J.2    McAlpine, J.B.3    Swanson, S.J.4    Katz, L.5
  • 10
    • 0030018666 scopus 로고    scopus 로고
    • Epothilons A and B: Antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria). Production, physico-chemical and biological properties
    • Gerth K., Bedorf N., Höfle G., Irschik H., Reichenbach H. Epothilons A and B: antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria). Production, physico-chemical and biological properties. J. Antibiot. 49:1996;560-563.
    • (1996) J. Antibiot. , vol.49 , pp. 560-563
    • Gerth, K.1    Bedorf, N.2    Höfle, G.3    Irschik, H.4    Reichenbach, H.5
  • 11
    • 0014157762 scopus 로고
    • Monensin, a new biologically active compound. V. Compounds related to monensin
    • Gorman M., Chamberlin J.W., Hamill R.L. Monensin, a new biologically active compound. V. Compounds related to monensin. Antimicrob. Agents Chemother. 7:1967;363-367.
    • (1967) Antimicrob. Agents Chemother. , vol.7 , pp. 363-367
    • Gorman, M.1    Chamberlin, J.W.2    Hamill, R.L.3
  • 12
    • 0028841535 scopus 로고
    • Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases
    • Haydock S.F., Aparicio J.F., Molnar I., Schwecke T., Khaw L.E., Konig A., Marsden A.F., Galloway I.S., Staunton J., Leadlay P.F. Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases. FEBS Lett. 374:1995;246-248.
    • (1995) FEBS Lett. , vol.374 , pp. 246-248
    • Haydock, S.F.1    Aparicio, J.F.2    Molnar, I.3    Schwecke, T.4    Khaw, L.E.5    Konig, A.6    Marsden, A.F.7    Galloway, I.S.8    Staunton, J.9    Leadlay, P.F.10
  • 13
    • 0025606149 scopus 로고
    • Molecular genetics of polyketides and its comparison to fatty acid biosynthesis
    • Hopwood D.A., Sherman D.H. Molecular genetics of polyketides and its comparison to fatty acid biosynthesis. Annu. Rev. Genet. 24:1990;37-66.
    • (1990) Annu. Rev. Genet. , vol.24 , pp. 37-66
    • Hopwood, D.A.1    Sherman, D.H.2
  • 14
    • 0033578297 scopus 로고    scopus 로고
    • Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis
    • Ikeda H., Nonomiya T., Usami M., Ohta T., Omura S. Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis. Proc. Natl. Acad. Sci. USA. 96:1999;9509-9514.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9509-9514
    • Ikeda, H.1    Nonomiya, T.2    Usami, M.3    Ohta, T.4    Omura, S.5
  • 15
    • 0032942468 scopus 로고    scopus 로고
    • FramePlot: A new implementation of the frame analysis for predicting protein-coding regions in bacterial DNA with a high G+C content
    • Ishikawa J., Hotta K. FramePlot: a new implementation of the frame analysis for predicting protein-coding regions in bacterial DNA with a high G+C content. FEMS Microbiol. Lett. 174:1999;251-253.
    • (1999) FEMS Microbiol. Lett. , vol.174 , pp. 251-253
    • Ishikawa, J.1    Hotta, K.2
  • 16
    • 0026742789 scopus 로고
    • Transfer of mobilizable plasmids to Sorangium cellulosum and evidence for their integration into the chromosome
    • Jaoua S., Neff S., Schupp T. Transfer of mobilizable plasmids to Sorangium cellulosum and evidence for their integration into the chromosome. Plasmid. 28:1992;157-165.
    • (1992) Plasmid , vol.28 , pp. 157-165
    • Jaoua, S.1    Neff, S.2    Schupp, T.3
  • 17
    • 0030693291 scopus 로고    scopus 로고
    • Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis
    • Kakavas S.J., Katz L., Stassi D. Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis. J. Bacteriol. 179:1997;7515-7522.
    • (1997) J. Bacteriol. , vol.179 , pp. 7515-7522
    • Kakavas, S.J.1    Katz, L.2    Stassi, D.3
  • 18
    • 0033080078 scopus 로고    scopus 로고
    • How do peptide synthetases generate structural diversity?
    • Konz D., Marahiel M.A. How do peptide synthetases generate structural diversity? Chem. Biol. 6:1999;R39-R48.
    • (1999) Chem. Biol. , vol.6 , pp. 39-R48
    • Konz, D.1    Marahiel, M.A.2
  • 19
    • 0031027531 scopus 로고    scopus 로고
    • Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R))
    • Kowalski R.J., Giannakakou P., Hamel E. Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)). J. Biol. Chem. 272:1997;2534-2541.
    • (1997) J. Biol. Chem. , vol.272 , pp. 2534-2541
    • Kowalski, R.J.1    Giannakakou, P.2    Hamel, E.3
  • 20
    • 0030445331 scopus 로고    scopus 로고
    • Production of a novel polyketide through the construction of a hybrid polyketide synthase
    • Kuhstoss S., Huber M., Turner J.R., Paschal J.W., Rao R.N. Production of a novel polyketide through the construction of a hybrid polyketide synthase. Gene. 183:1996;231-236.
    • (1996) Gene , vol.183 , pp. 231-236
    • Kuhstoss, S.1    Huber, M.2    Turner, J.R.3    Paschal, J.W.4    Rao, R.N.5
  • 22
    • 0025873287 scopus 로고
    • Biosynthesis of the immunosuppressant immunomycin: The enzymology of pipecolate incorporation
    • Nielsen J.B., Hsu M.J., Byrne K.M., Kaplan L. Biosynthesis of the immunosuppressant immunomycin: the enzymology of pipecolate incorporation. Biochemistry. 30:1991;5789-5796.
    • (1991) Biochemistry , vol.30 , pp. 5789-5796
    • Nielsen, J.B.1    Hsu, M.J.2    Byrne, K.M.3    Kaplan, L.4
  • 23
    • 0033582596 scopus 로고    scopus 로고
    • The first gene in the biosynthesis of the polyketide antibiotic TA of Myxococcus xanthui codes for a unique PKS module coupled to a peptide synthetase
    • Paitan Y., Alon G., Orr E., Ron E.Z., Rosenberg E. The first gene in the biosynthesis of the polyketide antibiotic TA of Myxococcus xanthui codes for a unique PKS module coupled to a peptide synthetase. J. Mol. Biol. 286:1999;465-474.
    • (1999) J. Mol. Biol. , vol.286 , pp. 465-474
    • Paitan, Y.1    Alon, G.2    Orr, E.3    Ron, E.Z.4    Rosenberg, E.5
  • 24
    • 0029006483 scopus 로고
    • A Sorangium cellulosum (Myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: Cloning, characterization and homology to polyketide synthase genes from actinomycetes
    • Schupp T., Toupet C., Cluzel B., Neff S., Hill S., Beck J., Ligon J.M. A Sorangium cellulosum (Myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization and homology to polyketide synthase genes from actinomycetes. J. Bacteriol. 177:1995;3673-3679.
    • (1995) J. Bacteriol. , vol.177 , pp. 3673-3679
    • Schupp, T.1    Toupet, C.2    Cluzel, B.3    Neff, S.4    Hill, S.5    Beck, J.6    Ligon, J.M.7
  • 26
    • 0033179468 scopus 로고    scopus 로고
    • The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases
    • Stachelhaus T., Mootz H.D., Marahiel M.A. The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases. Chem. Biol. 6:1999;493-505.
    • (1999) Chem. Biol. , vol.6 , pp. 493-505
    • Stachelhaus, T.1    Mootz, H.D.2    Marahiel, M.A.3
  • 27
    • 0034723333 scopus 로고    scopus 로고
    • Cloning and heterologous expression of the epothilone gene cluster
    • Tang L., Shah S., Chung L., Carney J., Katz L., Khosla C., Julien B. Cloning and heterologous expression of the epothilone gene cluster. Science. 287:2000;640-642.
    • (2000) Science , vol.287 , pp. 640-642
    • Tang, L.1    Shah, S.2    Chung, L.3    Carney, J.4    Katz, L.5    Khosla, C.6    Julien, B.7
  • 28
    • 0023634094 scopus 로고
    • Production of single-stranded plasmid DNA
    • Vieira J., Messing J. Production of single-stranded plasmid DNA. Methods Enzymol. 153:1987;3-11.
    • (1987) Methods Enzymol. , vol.153 , pp. 3-11
    • Vieira, J.1    Messing, J.2
  • 29
    • 0032514668 scopus 로고    scopus 로고
    • A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: Architecture of metabolic diversity
    • Xue Y., Zhao L., Liu H.W., Sherman D.H. A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity. Proc. Natl. Acad. Sci. USA. 95:1998;12111-12116.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12111-12116
    • Xue, Y.1    Zhao, L.2    Liu, H.W.3    Sherman, D.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.