-
1
-
-
0029822464
-
Reverse piedpiperase: Is the knockout mouse leading neuroscientists to a watery end?
-
Routtenberg, A., Reverse piedpiperase: is the knockout mouse leading neuroscientists to a watery end? Trends Neurosci., 19(11), 471-472, 1996.
-
(1996)
Trends Neurosci.
, vol.19
, Issue.11
, pp. 471-472
-
-
Routtenberg, A.1
-
2
-
-
0028899476
-
Knockout mouse fault lines
-
Routtenberg, A., Knockout mouse fault lines, Nature, 374(6520), 314-315, 1995.
-
(1995)
Nature
, vol.374
, Issue.6520
, pp. 314-315
-
-
Routtenberg, A.1
-
3
-
-
0029940557
-
Gene-targeting studies of mammalian behavior: Is it the mutation or the background genotype?
-
Gerlai, R., Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Trends Neurosci., 19(5), 177-181, 1996.
-
(1996)
Trends Neurosci.
, vol.19
, Issue.5
, pp. 177-181
-
-
Gerlai, R.1
-
4
-
-
0029790007
-
A biochemist's view of long-term potentiation
-
Roberson, E. D., English, J. D., and Sweatt, J. D., A biochemist's view of long-term potentiation, Learning Memory, 3, 1-24, 1996.
-
(1996)
Learning Memory
, vol.3
, pp. 1-24
-
-
Roberson, E.D.1
English, J.D.2
Sweatt, J.D.3
-
5
-
-
0031055834
-
Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain
-
Chen, C. and Tonegawa, S., Molecular genetic analysis of synaptic plasticity, activity-dependent neural development, learning, and memory in the mammalian brain., Annu. Rev. Neurosci., 20, 157-184, 1997.
-
(1997)
Annu. Rev. Neurosci.
, vol.20
, pp. 157-184
-
-
Chen, C.1
Tonegawa, S.2
-
6
-
-
0029097465
-
Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors
-
Gunther, U., Benson, J., Benke, D., Fritschy, J. M., Reyes, G., Knoflach, F., Crestani, F., Agazzi, A., Arigoni, M., Lang, Y., Bluethmann, H., Mohler, H., and Luscher, B., Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors, Proc. Natl. Acad. Sci. U.S.A., 92(17), 7749-7753, 1995.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, Issue.17
, pp. 7749-7753
-
-
Gunther, U.1
Benson, J.2
Benke, D.3
Fritschy, J.M.4
Reyes, G.5
Knoflach, F.6
Crestani, F.7
Agazzi, A.8
Arigoni, M.9
Lang, Y.10
Bluethmann, H.11
Mohler, H.12
Luscher, B.13
-
7
-
-
0024477606
-
A receptor subunit for benzodiazepine pharmacology
-
A receptor subunit for benzodiazepine pharmacology, Nature, 338(6216), 582-585, 1989.
-
(1989)
Nature
, vol.338
, Issue.6216
, pp. 582-585
-
-
Pritchett, D.B.1
Sontheimer, H.2
Shivers, B.D.3
Ymer, S.4
Kettenmann, H.5
Schofield, P.R.6
Seeburg, P.H.7
-
8
-
-
0030754563
-
The role of dopamine in the behavioral effects of caffeine in animals and humans
-
Garrett, B. E. and Griffiths, R. R., The role of dopamine in the behavioral effects of caffeine in animals and humans, Pharmacol. Biochem. Behav., 57(3), 533-541, 1997.
-
(1997)
Pharmacol. Biochem. Behav.
, vol.57
, Issue.3
, pp. 533-541
-
-
Garrett, B.E.1
Griffiths, R.R.2
-
9
-
-
0030841177
-
Aggressiveness, hypoalgesia, and high blood pressure in mice lacking the adenosine A2a receptor
-
Ledent, C., Vaugeois, J. M., Schiffmann, S. N., Pedrazzini, T., El Yacoubi, M., Vanderhaeghen, J. J., Costentin, J., Heath, J. K., Vassart, G., and Parmentier, M., Aggressiveness, hypoalgesia, and high blood pressure in mice lacking the adenosine A2a receptor, Nature, 388(6643), 674-678. 1997.
-
(1997)
Nature
, vol.388
, Issue.6643
, pp. 674-678
-
-
Ledent, C.1
Vaugeois, J.M.2
Schiffmann, S.N.3
Pedrazzini, T.4
El Yacoubi, M.5
Vanderhaeghen, J.J.6
Costentin, J.7
Heath, J.K.8
Vassart, G.9
Parmentier, M.10
-
10
-
-
0029328327
-
Steps towards a mouse model of Alzheimer's disease
-
Crowther, R., Steps towards a mouse model of Alzheimer's disease, BioEssays, 17(7), 593-595, 1995.
-
(1995)
BioEssays
, vol.17
, Issue.7
, pp. 593-595
-
-
Crowther, R.1
-
11
-
-
0029932831
-
Transgenic and knockout mice in the study of neurodegenerative diseases
-
Aguzzi, A., Brandner, S., Marino, S., and Steinbach, J., Transgenic and knockout mice in the study of neurodegenerative diseases, J. Mol. Med., 74, 111-126, 1996.
-
(1996)
J. Mol. Med.
, vol.74
, pp. 111-126
-
-
Aguzzi, A.1
Brandner, S.2
Marino, S.3
Steinbach, J.4
-
12
-
-
0030273627
-
Transgenic models of neurodegenerative diseases
-
Lee, M., Borchelt, D., Wong, P., Sisodia, S., and Price, D., Transgenic models of neurodegenerative diseases, Curr. Opin. Neurobiol., 6, 651-660, 1996.
-
(1996)
Curr. Opin. Neurobiol.
, vol.6
, pp. 651-660
-
-
Lee, M.1
Borchelt, D.2
Wong, P.3
Sisodia, S.4
Price, D.5
-
13
-
-
0029731654
-
Animal models for motor neuron diseases: Research directions
-
Ludolph, A., Animal models for motor neuron diseases: research directions, Neurology, 47, S228-S232, 1996.
-
(1996)
Neurology
, vol.47
-
-
Ludolph, A.1
-
14
-
-
0029969678
-
Mechanisms of selective motor neuron death in ALS: Insights from transgenic mouse models of motor neuron disease
-
Bruijn, L. and Cleveland, D., Mechanisms of selective motor neuron death in ALS: insights from transgenic mouse models of motor neuron disease, Neuropath. Appl. Neurobiol., 22, 373-387, 1996.
-
(1996)
Neuropath. Appl. Neurobiol.
, vol.22
, pp. 373-387
-
-
Bruijn, L.1
Cleveland, D.2
-
15
-
-
0030822582
-
Prion diseases and the BSE crisis
-
Prusiner, S., Prion diseases and the BSE crisis, Science, 278, 245-251, 1997.
-
(1997)
Science
, vol.278
, pp. 245-251
-
-
Prusiner, S.1
-
16
-
-
0030174981
-
The gene defects responsible for familial Alzheimer's disease
-
Tanzi, R. E., Kovacs, D. M., Kim, T. W., Moir, R. D., Guenette, S. Y., and Wasco, W., The gene defects responsible for familial Alzheimer's disease, Neurobiol. Dis., 3(3), 159-168, 1996.
-
(1996)
Neurobiol. Dis.
, vol.3
, Issue.3
, pp. 159-168
-
-
Tanzi, R.E.1
Kovacs, D.M.2
Kim, T.W.3
Moir, R.D.4
Guenette, S.Y.5
Wasco, W.6
-
17
-
-
0028018919
-
Behavioral and anatomical defects in mice homozygous for a modified β-amyloid precursor protein gene
-
Muller, U., Cristina, N., Li, Z.-W., Wolfer, D., Lipp, H.-P., Rulicke, T., Brandner, S., Aguzzi, A., and Weissmann, C., Behavioral and anatomical defects in mice homozygous for a modified β-amyloid precursor protein gene, Cell, 79, 755-765, 1994.
-
(1994)
Cell
, vol.79
, pp. 755-765
-
-
Muller, U.1
Cristina, N.2
Li, Z.-W.3
Wolfer, D.4
Lipp, H.-P.5
Rulicke, T.6
Brandner, S.7
Aguzzi, A.8
Weissmann, C.9
-
18
-
-
0028988801
-
β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
-
Zheng, H., Jiang, M., Trumbauer, M., Sirinath-singhji, S., Hopkins, R., Smith, D., Heavens, R., Dawson, G., Boyce, S., Conner, M., Stevens, K., Slunt, H., Sisodia, S., Chen, H., and Van der Ploeg, L., β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity, Cell, 81, 525-531, 1995.
-
(1995)
Cell
, vol.81
, pp. 525-531
-
-
Zheng, H.1
Jiang, M.2
Trumbauer, M.3
Sirinath-singhji, S.4
Hopkins, R.5
Smith, D.6
Heavens, R.7
Dawson, G.8
Boyce, S.9
Conner, M.10
Stevens, K.11
Slunt, H.12
Sisodia, S.13
Chen, H.14
Van Der Ploeg, L.15
-
19
-
-
0031470093
-
Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice
-
Vonkoch, C. S., Zheng, H., Chen, H., Trumbauer, M., Thinakaran, G., Vanderploeg, L. H. T., Price, D. L., and Sisodia, S. S., Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice, Neurobiol. Aging, 18(6), 661-669, 1997.
-
(1997)
Neurobiol. Aging
, vol.18
, Issue.6
, pp. 661-669
-
-
Vonkoch, C.S.1
Zheng, H.2
Chen, H.3
Trumbauer, M.4
Thinakaran, G.5
Vanderploeg, L.H.T.6
Price, D.L.7
Sisodia, S.S.8
-
20
-
-
0029788661
-
Enhanced amyloidogenic processing of the β-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Aβ sequence
-
Reaume, A., Rowland, D., Trusko, S., Savage, M., Lang, D., Greenberg, B., Siman, R., and Scott, R., Enhanced amyloidogenic processing of the β-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Aβ sequence, J. Biol. Chem., 271(38), 23380-23388, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.38
, pp. 23380-23388
-
-
Reaume, A.1
Rowland, D.2
Trusko, S.3
Savage, M.4
Lang, D.5
Greenberg, B.6
Siman, R.7
Scott, R.8
-
21
-
-
0030922421
-
Presenilins: Genes for life and death
-
Haass, C., Presenilins: genes for life and death, Neuron, 18, 687-690, 1997.
-
(1997)
Neuron
, vol.18
, pp. 687-690
-
-
Haass, C.1
-
22
-
-
0029784838
-
Amyloid beta-protein and the genetics of Alzheimer's disease
-
Selkoe, D. J., Amyloid beta-protein and the genetics of Alzheimer's disease, J. Biol. Chem., 271(31), 18295-18298, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.31
, pp. 18295-18298
-
-
Selkoe, D.J.1
-
23
-
-
0032556859
-
Deficiency in presenilin-1 inhibits the normal cleavage of amyloid precursor protein
-
De Strooper, B., Saftig, P., Craessaerts, K., Vanderstichele, H., Guhde, G., Annaert, W., Von Figura, K., and Van Leuven, F., Deficiency in presenilin-1 inhibits the normal cleavage of amyloid precursor protein, Nature, 391, 387-390, 1998.
-
(1998)
Nature
, vol.391
, pp. 387-390
-
-
De Strooper, B.1
Saftig, P.2
Craessaerts, K.3
Vanderstichele, H.4
Guhde, G.5
Annaert, W.6
Von Figura, K.7
Van Leuven, F.8
-
24
-
-
16044366039
-
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1
-
Duff, K., Eckman, C., Zehr, C., Yu, X., Prada, C. M., Perez-tur, J., Hutton, M., Buee, L., Harigaya, Y., Yager, D., Morgan, D., Gordon, M. N., Holcomb, L., Refolo, L., Zenk, B., Hardy, J., and Younkin, S., Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1, Nature, 383(6602), 710-713, 1996.
-
(1996)
Nature
, vol.383
, Issue.6602
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.M.5
Perez-tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
25
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice
-
Citron, M., Westaway, D., Xia, W., Carlson, G., Diehl, T., Levesque, G., Johnson-Wood, K., Lee, M., Seubert, P., Davis, A., Kholodenko, D., Motter, R., Sherrington, R., Perry, B., Yao, H., Strome, R., Lieberburg, L, Rommens, J., Kim, S., Schenk, D., Fraser, P., St. George Hyslop, P., and Selkoe, D., Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice, Nature Med., 3, 67-72, 1997.
-
(1997)
Nature Med.
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenko, D.11
Motter, R.12
Sherrington, R.13
Perry, B.14
Yao, H.15
Strome, R.16
Lieberburg, L.17
Rommens, J.18
Kim, S.19
Schenk, D.20
Fraser, P.21
St. George Hyslop, P.22
Selkoe, D.23
more..
-
26
-
-
0029938431
-
Rational design of an animal model for Alzheimer's disease: Introduction of multiple human genomic transgenes to reproduce pathology in a rodent
-
Loring, J., Paszty, C., Rose, A., McIntosh, T., Murai, H., Pierce, J., Schramm, S., Wymore, K., Lee, V.-Y., Trojanowski, J., and Peterson, K., Rational design of an animal model for Alzheimer's disease: introduction of multiple human genomic transgenes to reproduce pathology in a rodent, Neurobiol. Aging, 17, 173-182, 1996.
-
(1996)
Neurobiol. Aging
, vol.17
, pp. 173-182
-
-
Loring, J.1
Paszty, C.2
Rose, A.3
McIntosh, T.4
Murai, H.5
Pierce, J.6
Schramm, S.7
Wymore, K.8
Lee, V.-Y.9
Trojanowski, J.10
Peterson, K.11
-
27
-
-
0028844138
-
Neurodegeneration in the central nervous system of apoE-deficient mice
-
Masliah, E., Mallory, M., Ge, N., Alford, M., Veinbergs, I., and Roses, A. D., Neurodegeneration in the central nervous system of apoE-deficient mice, Exp. Neurol., 136(2), 107-122, 1995.
-
(1995)
Exp. Neurol.
, vol.136
, Issue.2
, pp. 107-122
-
-
Masliah, E.1
Mallory, M.2
Ge, N.3
Alford, M.4
Veinbergs, I.5
Roses, A.D.6
-
28
-
-
0028793430
-
Phosphorylation of tau in apolipoprotein E-deficient mice
-
Genis, I., Gordon, I., Sehayck, E., and Michaelson, D. M., Phosphorylation of tau in apolipoprotein E-deficient mice, Neurosci. Lett., 199(1), 5-8, 1995.
-
(1995)
Neurosci. Lett.
, vol.199
, Issue.1
, pp. 5-8
-
-
Genis, I.1
Gordon, I.2
Sehayck, E.3
Michaelson, D.M.4
-
29
-
-
0030897921
-
Severe learning deficits in apolipoprotein E-knockout mice in a water maze task
-
Oitzl, M. S., Mulder, M., Lucassen, P. J., Havekes, L. M., Grootendorst, J., and de Kloet, E. R., Severe learning deficits in apolipoprotein E-knockout mice in a water maze task, Brain Res., 752(1-2), 189-196, 1997.
-
(1997)
Brain Res.
, vol.752
, Issue.1-2
, pp. 189-196
-
-
Oitzl, M.S.1
Mulder, M.2
Lucassen, P.J.3
Havekes, L.M.4
Grootendorst, J.5
De Kloet, E.R.6
-
30
-
-
0028790904
-
Memory deficits and cholinergic impairments in apolipoprotein E-deficient mice
-
Gordon, I., Grauer, E., Genis, I., Sehayek, E., and Michaelson, D. M., Memory deficits and cholinergic impairments in apolipoprotein E-deficient mice, Neurosci. Lett., 199(1), 1-4, 1995.
-
(1995)
Neurosci. Lett.
, vol.199
, Issue.1
, pp. 1-4
-
-
Gordon, I.1
Grauer, E.2
Genis, I.3
Sehayek, E.4
Michaelson, D.M.5
-
31
-
-
0028049335
-
Hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency: Identification of point mutations in Japanese patients with Lesch-Nyhan syndrome and hereditary gout and their permanent expression in an HPRT-deficient mouse cell line
-
Tohyama, J., Nanba, E., and Ohno, K., Hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency: identification of point mutations in Japanese patients with Lesch-Nyhan syndrome and hereditary gout and their permanent expression in an HPRT-deficient mouse cell line, Hum. Genet., 93(2), 175-181, 1994.
-
(1994)
Hum. Genet.
, vol.93
, Issue.2
, pp. 175-181
-
-
Tohyama, J.1
Nanba, E.2
Ohno, K.3
-
32
-
-
0027461605
-
Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice
-
Wu, C. L. and Melton, D. W., Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice, Nat. Genet., 3(3), 235-240, 1993.
-
(1993)
Nat. Genet.
, vol.3
, Issue.3
, pp. 235-240
-
-
Wu, C.L.1
Melton, D.W.2
-
33
-
-
0030222252
-
Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains
-
Stevens, K. E., Freedman, R., Collins, A. C., Hall, M., Leonard, S., Marks, M. J., and Rose, G. M., Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains, Neuropsychopharmacology, 15(2), 152-162, 1996.
-
(1996)
Neuropsychopharmacology
, vol.15
, Issue.2
, pp. 152-162
-
-
Stevens, K.E.1
Freedman, R.2
Collins, A.C.3
Hall, M.4
Leonard, S.5
Marks, M.J.6
Rose, G.M.7
-
34
-
-
0009703087
-
Behavioral phenotypes of inbred mouse strains: Implications and recommendations for molecular studies
-
Crawley, J. N., Belknap, J. K., Collins, A., Crabbe, J. C., Frankel, W., Henderson, N., Hitzemann, R. J., Maxson, S. C., Miner, L. L., Silva, A. J., Wehner, J. M., Wynshaw-Boris, A., and Paylor, R., Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies, Psychopharmacology, 132(2), 107-124, 1997.
-
(1997)
Psychopharmacology
, vol.132
, Issue.2
, pp. 107-124
-
-
Crawley, J.N.1
Belknap, J.K.2
Collins, A.3
Crabbe, J.C.4
Frankel, W.5
Henderson, N.6
Hitzemann, R.J.7
Maxson, S.C.8
Miner, L.L.9
Silva, A.J.10
Wehner, J.M.11
Wynshaw-Boris, A.12
Paylor, R.13
-
35
-
-
0027092647
-
Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice
-
Grant, S. G. N., O'Dell, T. J., Karl, K. A., Stein, P. L., Soriano, P., and Kandel, E. R., Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice, Science, 258, 1903-1910, 1992.
-
(1992)
Science
, vol.258
, pp. 1903-1910
-
-
Grant, S.G.N.1
O'Dell, T.J.2
Karl, K.A.3
Stein, P.L.4
Soriano, P.5
Kandel, E.R.6
-
36
-
-
0030970839
-
Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene
-
Kojima, N., Wang, J., Mansuy, I. M., Grant, S. G., Mayford, M., and Kandel, E. R., Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene, Proc. Natl. Acad. Sci. U.S.A., 94(9), 4761-4765, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.9
, pp. 4761-4765
-
-
Kojima, N.1
Wang, J.2
Mansuy, I.M.3
Grant, S.G.4
Mayford, M.5
Kandel, E.R.6
-
37
-
-
0027379724
-
Defects in mesoderm, neural tube, and vascular development in mouse embryos lacking fibronectin
-
George, E. L., Georges-Labouesse, E. N., Patel-King, R. S., Rayburn, H., and Hynes, R. O., Defects in mesoderm, neural tube, and vascular development in mouse embryos lacking fibronectin, Development, 119(4), 1079-1091, 1993.
-
(1993)
Development
, vol.119
, Issue.4
, pp. 1079-1091
-
-
George, E.L.1
Georges-Labouesse, E.N.2
Patel-King, R.S.3
Rayburn, H.4
Hynes, R.O.5
-
38
-
-
9044222485
-
Neuronal abnormalities in microtubule-associated protein 1B mutant mice
-
Edelmann, W., Zervas, M., Costello, P., Roback, L., Fischer, I., Hammarback, J. A., Cowan, N., Davies, P., Wainer, B., and Kucherlapati, R., Neuronal abnormalities in microtubule-associated protein 1B mutant mice, Proc. Natl. Acad. Sci U.S.A., 93(3), 1270-1275, 1996
-
(1996)
Proc. Natl. Acad. Sci U.S.A.
, vol.93
, Issue.3
, pp. 1270-1275
-
-
Edelmann, W.1
Zervas, M.2
Costello, P.3
Roback, L.4
Fischer, I.5
Hammarback, J.A.6
Cowan, N.7
Davies, P.8
Wainer, B.9
Kucherlapati, R.10
-
39
-
-
0031419532
-
Skin abnormality in aged fyn-/- fak+/- mice
-
Ilic, D., Kanazawa, S., Nishizumi, H., Aizawa, S., Kuroki, T., Mori, S., and Yamamoto, T., Skin abnormality in aged fyn-/-fak+/-mice, Carcinogenesis, 18(8), 1473-1476, 1997.
-
(1997)
Carcinogenesis
, vol.18
, Issue.8
, pp. 1473-1476
-
-
Ilic, D.1
Kanazawa, S.2
Nishizumi, H.3
Aizawa, S.4
Kuroki, T.5
Mori, S.6
Yamamoto, T.7
-
40
-
-
0029021176
-
Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase
-
Brandon, E. P., Zhuo, M., Huang, Y. Y., Qi, M., Gerhold, K. A., Burton, K. A., Kandel, E. R., McKnight, G. S., and Idzerda, R. L., Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase, Proc. Natl. Acad. Sci. U.S.A., 92(19), 8851-8855, 1995.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, Issue.19
, pp. 8851-8855
-
-
Brandon, E.P.1
Zhuo, M.2
Huang, Y.Y.3
Qi, M.4
Gerhold, K.A.5
Burton, K.A.6
Kandel, E.R.7
McKnight, G.S.8
Idzerda, R.L.9
-
41
-
-
0029980672
-
Targeting of the CREB gene leads to upregulation of a novel CREB mRNA isoform
-
Blendy, J. A., Kaestner, K. H., Schmid, W., Gass, P., and Schutz, G., Targeting of the CREB gene leads to upregulation of a novel CREB mRNA isoform, EMBO J., 15(5), 1098-1106, 1996.
-
(1996)
EMBO J.
, vol.15
, Issue.5
, pp. 1098-1106
-
-
Blendy, J.A.1
Kaestner, K.H.2
Schmid, W.3
Gass, P.4
Schutz, G.5
-
42
-
-
0028238472
-
Targeted mutation of the CREB gene: Compensation within the CREB/ATF family of transcription factors
-
Hummler, E., Cole, T. J., Blendy, J. A., Ganss, R., Agazzi, A., Schmid, W., Beermann, F., and Schutz, G., Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors, Proc. Natl. Acad. Sci. U.S.A., 91(12), 5647-5651, 1994.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, Issue.12
, pp. 5647-5651
-
-
Hummler, E.1
Cole, T.J.2
Blendy, J.A.3
Ganss, R.4
Agazzi, A.5
Schmid, W.6
Beermann, F.7
Schutz, G.8
-
43
-
-
0032516040
-
Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein
-
Rudolph, D., Tafuri, A., Gass, P., Hammerling, G. J., Arnold, B., and Schutz, G., Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein, Proc. Natl. Acad. Sci. U.S.A., 95, 4481-4486, 1998.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 4481-4486
-
-
Rudolph, D.1
Tafuri, A.2
Gass, P.3
Hammerling, G.J.4
Arnold, B.5
Schutz, G.6
-
44
-
-
0028059637
-
Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS
-
O'Dell, T. J., Huang, P. L., Dawson, T. M., Dinerman, J. L., Snyder, S. H., Kandel, E. R., and Fishman, M. C., Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS, Science, 265(5171), 542-546, 1994.
-
(1994)
Science
, vol.265
, Issue.5171
, pp. 542-546
-
-
O'Dell, T.J.1
Huang, P.L.2
Dawson, T.M.3
Dinerman, J.L.4
Snyder, S.H.5
Kandel, E.R.6
Fishman, M.C.7
-
45
-
-
0030582764
-
Long-term potentiation is reduced in mice that are doubly mutant in endothelial and neuronal nitric oxide synthase
-
Son, H., Hawkins, R. D., Martin, K., Kiebler, M., Huang, P. L., Fishman, M. C., and Kandel, E. R., Long-term potentiation is reduced in mice that are doubly mutant in endothelial and neuronal nitric oxide synthase, Cell, 87(6), 1015-1023, 1996.
-
(1996)
Cell
, vol.87
, Issue.6
, pp. 1015-1023
-
-
Son, H.1
Hawkins, R.D.2
Martin, K.3
Kiebler, M.4
Huang, P.L.5
Fishman, M.C.6
Kandel, E.R.7
-
46
-
-
16944366300
-
A receptor alpha6 subunit gene inactivation inhibits delta subunit expression
-
A receptor alpha6 subunit gene inactivation inhibits delta subunit expression, J. Neurosci., 17(4), 1350-1362, 1997.
-
(1997)
J. Neurosci.
, vol.17
, Issue.4
, pp. 1350-1362
-
-
Jones, A.1
Korpi, E.R.2
McKernan, R.M.3
Pelz, R.4
Nusser, Z.5
Makela, R.6
Mellor, J.R.7
Pollard, S.8
Bahn, S.9
Stephenson, F.A.10
Randall, A.D.11
Sieghart, W.12
Somogyi, P.13
Smith, A.J.H.14
Wisden, W.15
-
47
-
-
0027945523
-
Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses
-
Xu, M., Moratalla, R., Gold, L. H., Hiroi, N., Koob, G. F., Graybiel, A. M., and Tonegawa, S., Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses, Cell, 79(4), 729-742, 1994.
-
(1994)
Cell
, vol.79
, Issue.4
, pp. 729-742
-
-
Xu, M.1
Moratalla, R.2
Gold, L.H.3
Hiroi, N.4
Koob, G.F.5
Graybiel, A.M.6
Tonegawa, S.7
-
48
-
-
0004027995
-
-
Oxford University Press, New York
-
Cooper, J. R., Bloom, F. E., and Roth, R. H., The Biochemical Basis of Neuropharmacology, Oxford University Press, New York, 1996.
-
(1996)
The Biochemical Basis of Neuropharmacology
-
-
Cooper, J.R.1
Bloom, F.E.2
Roth, R.H.3
-
49
-
-
0028912476
-
Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development
-
Zhou, Q. Y., Quaife, C. J., and Palmiter, R. D., Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development, Nature, 374(6523), 640-643, 1995.
-
(1995)
Nature
, vol.374
, Issue.6523
, pp. 640-643
-
-
Zhou, Q.Y.1
Quaife, C.J.2
Palmiter, R.D.3
-
50
-
-
0029588435
-
Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic
-
Zhou, Q. Y. and Palmiter, R. D., Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic, Cell, 83(7), 1197-1209, 1995.
-
(1995)
Cell
, vol.83
, Issue.7
, pp. 1197-1209
-
-
Zhou, Q.Y.1
Palmiter, R.D.2
-
51
-
-
0030460425
-
Subregion- and cell type-restricted gene knockout in mouse brain
-
Tsien, J. Z., Chen, D. F., Gerber, D., Tom, C., Mercer, E. H., Anderson, D. J., Mayford, M., Kandel, E. R., and Tonegawa, S., Subregion-and cell type-restricted gene knockout in mouse brain, Cell, 87, 1317-1326, 1996.
-
(1996)
Cell
, vol.87
, pp. 1317-1326
-
-
Tsien, J.Z.1
Chen, D.F.2
Gerber, D.3
Tom, C.4
Mercer, E.H.5
Anderson, D.J.6
Mayford, M.7
Kandel, E.R.8
Tonegawa, S.9
-
52
-
-
0030018512
-
The use of null mutant mice to study complex learning and memory processes
-
Wehner, J. M., Bowers, B. J., and Paylor, R., The use of null mutant mice to study complex learning and memory processes, Behav. Genet., 26(3), 301-312, 1996.
-
(1996)
Behav. Genet.
, vol.26
, Issue.3
, pp. 301-312
-
-
Wehner, J.M.1
Bowers, B.J.2
Paylor, R.3
-
53
-
-
0025744331
-
Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology
-
Gora-Maslak, G., McClearn, G. E., Crabbe, J. C., Phillips, T. J., Belknap, J. K., and Plomin, R., Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology, Psychopharmacology, 104(4), 413-424, 1991.
-
(1991)
Psychopharmacology
, vol.104
, Issue.4
, pp. 413-424
-
-
Gora-Maslak, G.1
McClearn, G.E.2
Crabbe, J.C.3
Phillips, T.J.4
Belknap, J.K.5
Plomin, R.6
-
54
-
-
0025909974
-
Use of recombinant inbred strains to detect quantitative trait loci associated with behavior
-
Plomin, R., McClearn, G. E., Gora-Maslak, G., and Neiderhiser, J. M., Use of recombinant inbred strains to detect quantitative trait loci associated with behavior, Behav. Genet., 21(2), 99-116, 1991.
-
(1991)
Behav. Genet.
, vol.21
, Issue.2
, pp. 99-116
-
-
Plomin, R.1
McClearn, G.E.2
Gora-Maslak, G.3
Neiderhiser, J.M.4
-
56
-
-
0029925695
-
Unusual behavioral phenotypes of inbred mouse strains
-
Crawley, J. N., Unusual behavioral phenotypes of inbred mouse strains, Trends Neurosci., 19(5), 181-182, 1996.
-
(1996)
Trends Neurosci.
, vol.19
, Issue.5
, pp. 181-182
-
-
Crawley, J.N.1
-
57
-
-
0030777698
-
Mutant mice and neuroscience - Recommendations concerning genetic background
-
Silva, A. J., Simpson, E. M., Takahashi, J. S., Lipp, H.-P., Nakanishi, S., Wehner, J. M., Giese, K. P., Tully, T., Abel, T., Chapman, P. F., Grant, S., Itohara, S., Lathe, R., Mayford, M., McNamara, J. O., Morris, R. J., Picciotto, M., Roder, J., Shin, H.-S., Slesinger, P. A., Storm, D. R., Stryker, M. P., Tonegawa, S., Wang, Y., and Wolfer, D. P., Mutant mice and neuroscience - recommendations concerning genetic background, Neuron, 19(4), 755-759, 1997.
-
(1997)
Neuron
, vol.19
, Issue.4
, pp. 755-759
-
-
Silva, A.J.1
Simpson, E.M.2
Takahashi, J.S.3
Lipp, H.-P.4
Nakanishi, S.5
Wehner, J.M.6
Giese, K.P.7
Tully, T.8
Abel, T.9
Chapman, P.F.10
Grant, S.11
Itohara, S.12
Lathe, R.13
Mayford, M.14
McNamara, J.O.15
Morris, R.J.16
Picciotto, M.17
Roder, J.18
Shin, H.-S.19
Slesinger, P.A.20
Storm, D.R.21
Stryker, M.P.22
Tonegawa, S.23
Wang, Y.24
Wolfer, D.P.25
more..
-
58
-
-
0022567742
-
Embryo-derived stem cells: A tool for elucidating the developmental genetics of the mouse
-
Bradley, A. and Robertson, E., Embryo-derived stem cells: a tool for elucidating the developmental genetics of the mouse, Curr. Top. Dev. Biol., 20, 357-371, 1986.
-
(1986)
Curr. Top. Dev. Biol.
, vol.20
, pp. 357-371
-
-
Bradley, A.1
Robertson, E.2
-
59
-
-
0030267396
-
Bypass of lethality with mosaic mice generated by Cre-loxP-mediated recombination
-
Betz, U. A., Vosshenrich, C. A., Rajewsky, K., and Muller, W., Bypass of lethality with mosaic mice generated by Cre-loxP-mediated recombination, Curr. Biol., 6(10), 1307-1316, 1996.
-
(1996)
Curr. Biol.
, vol.6
, Issue.10
, pp. 1307-1316
-
-
Betz, U.A.1
Vosshenrich, C.A.2
Rajewsky, K.3
Muller, W.4
-
60
-
-
0028675511
-
Cre-loxP-mediated gene replacement: A mouse strain producing humanized antibodies
-
Zou, Y. R., Muller, W., Gu, H., and Rajewsky, K., Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies, Curr. Biol., 4(12), 1099-1103, 1994.
-
(1994)
Curr. Biol.
, vol.4
, Issue.12
, pp. 1099-1103
-
-
Zou, Y.R.1
Muller, W.2
Gu, H.3
Rajewsky, K.4
-
61
-
-
0029586870
-
Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system
-
Hennighausen, L., Wall, R. J., Tillmann, U., Li, M., and Furth, P. A., Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system, J. Cell. Biochem., 59(4), 463-472, 1995.
-
(1995)
J. Cell. Biochem.
, vol.59
, Issue.4
, pp. 463-472
-
-
Hennighausen, L.1
Wall, R.J.2
Tillmann, U.3
Li, M.4
Furth, P.A.5
-
62
-
-
0024041732
-
Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1
-
Sauer, B. and Henderson, N., Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1, Proc. Natl. Acad. Sci. U.S.A., 85(14), 5166-5170, 1988.
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, Issue.14
, pp. 5166-5170
-
-
Sauer, B.1
Henderson, N.2
-
63
-
-
0030446363
-
The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory
-
Tsien, J. Z., Huerta, P. T., and Tonegawa, S., The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory, Cell, 87(7), 1327-1338, 1996.
-
(1996)
Cell
, vol.87
, Issue.7
, pp. 1327-1338
-
-
Tsien, J.Z.1
Huerta, P.T.2
Tonegawa, S.3
-
64
-
-
0029155706
-
Inducible gene targeting in mice
-
Kuhn, R., Schwenk, F., Aguet, M., and Rajewsky, K., Inducible gene targeting in mice, Science, 269(5229), 1427-1429, 1995.
-
(1995)
Science
, vol.269
, Issue.5229
, pp. 1427-1429
-
-
Kuhn, R.1
Schwenk, F.2
Aguet, M.3
Rajewsky, K.4
-
65
-
-
0029788269
-
Temporal control of the Cre recombinase in transgenic mice by a tetracycline responsive promoter
-
St-Onge, L., Furth, P. A., and Gruss, P., Temporal control of the Cre recombinase in transgenic mice by a tetracycline responsive promoter, Nucleic Acids Res., 24(19), 3875-3877, 1996.
-
(1996)
Nucleic Acids Res.
, vol.24
, Issue.19
, pp. 3875-3877
-
-
St-Onge, L.1
Furth, P.A.2
Gruss, P.3
-
66
-
-
0029767838
-
Ligand-activated site-specific recombination in mice
-
Feil, R., Brocard, J., Mascrez, B., LeMeur, M., Metzger, D., and Chambon, P., Ligand-activated site-specific recombination in mice, Proc. Natl. Acad. Sci. U.S.A., 93(20), 10887-10890, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.20
, pp. 10887-10890
-
-
Feil, R.1
Brocard, J.2
Mascrez, B.3
Lemeur, M.4
Metzger, D.5
Chambon, P.6
-
67
-
-
0028027484
-
Inducible gene expression systems for higher eukaryotic cells
-
Gossen, M., Bonin, A. L., Freundlieb, S., and Bujard, H., Inducible gene expression systems for higher eukaryotic cells, Curr. Opin. Biotechnol., 5(5), 516-520, 1994.
-
(1994)
Curr. Opin. Biotechnol.
, vol.5
, Issue.5
, pp. 516-520
-
-
Gossen, M.1
Bonin, A.L.2
Freundlieb, S.3
Bujard, H.4
-
68
-
-
0031667482
-
Transgenic animals with inducible, targeted gene expression in brain
-
Chen, J. S., Kelz, M. B., Zeng, G. Q., Sakai, N., Steffen, C., Shockett, P. E., Picciotto, M. R., Duman, R. S., and Nestler, E. J., Transgenic animals with inducible, targeted gene expression in brain, Mol. Pharmacol., 54(3), 495-503, 1998.
-
(1998)
Mol. Pharmacol.
, vol.54
, Issue.3
, pp. 495-503
-
-
Chen, J.S.1
Kelz, M.B.2
Zeng, G.Q.3
Sakai, N.4
Steffen, C.5
Shockett, P.E.6
Picciotto, M.R.7
Duman, R.S.8
Nestler, E.J.9
-
69
-
-
0032498227
-
Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory
-
Mansuy, I. M., Mayford, M., Jacob, B., Kandel, E. R., and Bach, M. E., Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory, Cell, 92, 39-49, 1998.
-
(1998)
Cell
, vol.92
, pp. 39-49
-
-
Mansuy, I.M.1
Mayford, M.2
Jacob, B.3
Kandel, E.R.4
Bach, M.E.5
-
70
-
-
0029807527
-
Control of memory formation through regulated expression of a CaMKII transgene
-
Mayford, M., Bach, M. E., Huang, Y. Y., Wang, L., Hawkins, R. D. and Kandel, E. R., Control of memory formation through regulated expression of a CaMKII transgene, Science, 274(5293), 1678-1683, 1996.
-
(1996)
Science
, vol.274
, Issue.5293
, pp. 1678-1683
-
-
Mayford, M.1
Bach, M.E.2
Huang, Y.Y.3
Wang, L.4
Hawkins, R.D.5
Kandel, E.R.6
-
71
-
-
0029086350
-
A mouse model for the cystic fibrosis delta F508 mutation
-
van Doorninck, J. H., French, P. J., Verbeek, E., Peters, R. H., Morreau, H., Bijman, J., and Scholte, B. J., A mouse model for the cystic fibrosis delta F508 mutation, EMBO J., 14(18), 4403-4411, 1995.
-
(1995)
EMBO J.
, vol.14
, Issue.18
, pp. 4403-4411
-
-
Van Doorninck, J.H.1
French, P.J.2
Verbeek, E.3
Peters, R.H.4
Morreau, H.5
Bijman, J.6
Scholte, B.J.7
-
72
-
-
0032488659
-
Autophosphorylation at Thr(286) of the alpha calcium-calmodulin kinase II in LTP and learning
-
Giese, K. P., Fedorov, N. B., Filipkowski, R. K., and Silva, A. J., Autophosphorylation at Thr(286) of the alpha calcium-calmodulin kinase II in LTP and learning, Science, 279(5352), 870-873, 1998.
-
(1998)
Science
, vol.279
, Issue.5352
, pp. 870-873
-
-
Giese, K.P.1
Fedorov, N.B.2
Filipkowski, R.K.3
Silva, A.J.4
-
73
-
-
0032489034
-
Abnormal hippocarnpal spatial representations in alpha-CaMKIIT286A and CREB-alpha-delta-mice
-
Cho, Y. H., Giese, K. P., Tanila, H., Silva, A. J., and Eichenbaum, H., Abnormal hippocarnpal spatial representations in alpha-CaMKIIT286A and CREB-alpha-delta-mice, Science, 279(5352), 867-869, 1998.
-
(1998)
Science
, vol.279
, Issue.5352
, pp. 867-869
-
-
Cho, Y.H.1
Giese, K.P.2
Tanila, H.3
Silva, A.J.4
Eichenbaum, H.5
-
74
-
-
0030846807
-
Antisense oligonucleotides in psychopharmacology and behaviour: Promises and pitfalls
-
Robinson, E. S., Nutt, D. J., Jackson, H. C., and Hudson, A. L., Antisense oligonucleotides in psychopharmacology and behaviour: promises and pitfalls, J. Psychopharmacol., 11(3), 259-269, 1997.
-
(1997)
J. Psychopharmacol.
, vol.11
, Issue.3
, pp. 259-269
-
-
Robinson, E.S.1
Nutt, D.J.2
Jackson, H.C.3
Hudson, A.L.4
-
75
-
-
0031912506
-
Antisense oligonucleotides: Is the glass half full or half empty?
-
Bennett, C. F., Antisense oligonucleotides: is the glass half full or half empty? Biochem. Pharmacol., 55(1), 9-19, 1998.
-
(1998)
Biochem. Pharmacol.
, vol.55
, Issue.1
, pp. 9-19
-
-
Bennett, C.F.1
-
76
-
-
0027249144
-
Induction of G alpha i2-specific antisense RNA in vivo inhibits neonatal growth
-
Moxham, C. M., Hod, Y., and Malbon, C. C., Induction of G alpha i2-specific antisense RNA in vivo inhibits neonatal growth, Science, 260(5110), 991-995, 1993.
-
(1993)
Science
, vol.260
, Issue.5110
, pp. 991-995
-
-
Moxham, C.M.1
Hod, Y.2
Malbon, C.C.3
-
77
-
-
0030945024
-
Downregulation of RAR alpha in mice by antisense transgene leads to a compensatory increase in RAR beta and RAR gamma and development of lymphoma
-
Manshouri, T., Yang, Y., Lin, H., Stass, S. A., Glassman, A. B., Keating, M. J., and Albitar, M., Downregulation of RAR alpha in mice by antisense transgene leads to a compensatory increase in RAR beta and RAR gamma and development of lymphoma, Blood, 89(7), 2507-2515, 1997.
-
(1997)
Blood
, vol.89
, Issue.7
, pp. 2507-2515
-
-
Manshouri, T.1
Yang, Y.2
Lin, H.3
Stass, S.A.4
Glassman, A.B.5
Keating, M.J.6
Albitar, M.7
-
78
-
-
0026543152
-
Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene
-
Pepin, M. C., Pothier, F., and Barden, N., Impaired type II glucocorticoid-receptor function in mice bearing antisense RNA transgene, Nature, 355(6362), 725-728, 1992.
-
(1992)
Nature
, vol.355
, Issue.6362
, pp. 725-728
-
-
Pepin, M.C.1
Pothier, F.2
Barden, N.3
-
79
-
-
0032557837
-
Age- and stimulus-dependent changes in anxiety-related behaviour of transgenic mice with GR dysfunction
-
Strohle, A., Poettig, M., Barden, N., Holsboer, F., and Montkowski, A., Age-and stimulus-dependent changes in anxiety-related behaviour of transgenic mice with GR dysfunction, Neuroreport, 9(9), 2099-2102, 1998.
-
(1998)
Neuroreport
, vol.9
, Issue.9
, pp. 2099-2102
-
-
Strohle, A.1
Poettig, M.2
Barden, N.3
Holsboer, F.4
Montkowski, A.5
-
80
-
-
0028894954
-
Long-term antidepressant treatment reduces behavioural deficits in transgenic mice with impaired glucocorticoid receptor function
-
Montkowski, A., Barden, N., Wotjak, C., Stec, I., Ganster, J., Meaney, M., Engelmann, M., Real, J. M., Landgraf, R., and Holsboer, F., Long-term antidepressant treatment reduces behavioural deficits in transgenic mice with impaired glucocorticoid receptor function, J. Neuroendocrinol., 7(11), 841-845, 1995.
-
(1995)
J. Neuroendocrinol.
, vol.7
, Issue.11
, pp. 841-845
-
-
Montkowski, A.1
Barden, N.2
Wotjak, C.3
Stec, I.4
Ganster, J.5
Meaney, M.6
Engelmann, M.7
Real, J.M.8
Landgraf, R.9
Holsboer, F.10
-
81
-
-
0029909474
-
Gene delivery to the central and peripheral nervous systems of mice using HSV1 ICP34.5 deletion mutant vectors
-
Coffin, R. S., MacLean, A. R., Latchman, D. S., and Brown, S. M., Gene delivery to the central and peripheral nervous systems of mice using HSV1 ICP34.5 deletion mutant vectors, Gene Ther., 3(10), 886-891, 1996.
-
(1996)
Gene Ther.
, vol.3
, Issue.10
, pp. 886-891
-
-
Coffin, R.S.1
MacLean, A.R.2
Latchman, D.S.3
Brown, S.M.4
-
82
-
-
0030868549
-
Versatile retrovirus vector systems for regulated gene expression in vitro and in vivo
-
Lindemann, D., Patriquin, E., Feng, S., and Mulligan, R. C., Versatile retrovirus vector systems for regulated gene expression in vitro and in vivo, Mol. Med., 3(7), 466-476, 1997.
-
(1997)
Mol. Med.
, vol.3
, Issue.7
, pp. 466-476
-
-
Lindemann, D.1
Patriquin, E.2
Feng, S.3
Mulligan, R.C.4
-
83
-
-
0031437964
-
Suppression of neuronal and cardiac transient outward currents by viral gene transfer of dominant-negative Kv4.2 constructs
-
Johns, D. C., Nuss, H. B., and Marban, E., Suppression of neuronal and cardiac transient outward currents by viral gene transfer of dominant-negative Kv4.2 constructs, J. Biol. Chem., 272(50), 31598-31603, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, Issue.50
, pp. 31598-31603
-
-
Johns, D.C.1
Nuss, H.B.2
Marban, E.3
-
84
-
-
0030461049
-
Reduction of type V collagen using a dominant-negative strategy alters the regulation of fibrillogenesis and results in the loss of corneal-specific fibril morphology
-
Marchant, J. K., Hahn, R. A., Linsenmayer, T. F., and Birk, D. E., Reduction of type V collagen using a dominant-negative strategy alters the regulation of fibrillogenesis and results in the loss of corneal-specific fibril morphology, J. Cell. Biol., 135(5), 1415-1426, 1996.
-
(1996)
J. Cell. Biol.
, vol.135
, Issue.5
, pp. 1415-1426
-
-
Marchant, J.K.1
Hahn, R.A.2
Linsenmayer, T.F.3
Birk, D.E.4
-
85
-
-
0029910815
-
Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice
-
Korte, M., Griesbeck, O., Gravel, C., Carroll, P., Staiger, V., Thoenen, H., and Bonhoeffer, T., Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice, Proc. Natl. Acad. Sci. U.S.A., 93(22), 12547-12552, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.22
, pp. 12547-12552
-
-
Korte, M.1
Griesbeck, O.2
Gravel, C.3
Carroll, P.4
Staiger, V.5
Thoenen, H.6
Bonhoeffer, T.7
-
86
-
-
0028241271
-
Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior
-
Vitaterna, M. H., King, D. P., Chang, A. M., Kernhauser, J. M., Lowrey, P. L., McDonald, J. D., Dove, W. F., Pinto, L. H., Turek, F. W., and Takahashi, J. S., Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior, Science, 264(5159), 719-725, 1994.
-
(1994)
Science
, vol.264
, Issue.5159
, pp. 719-725
-
-
Vitaterna, M.H.1
King, D.P.2
Chang, A.M.3
Kernhauser, J.M.4
Lowrey, P.L.5
McDonald, J.D.6
Dove, W.F.7
Pinto, L.H.8
Turek, F.W.9
Takahashi, J.S.10
-
87
-
-
20244377493
-
Positional cloning of the mouse circadian clock gene
-
King, D.P., Zhao, Y.,Sangoram, A.M., Wilsbacher, L. D., Tanaka, M., Antoch, M. P., Steeves, T. D., Vitaterna, M. H., Kornhauser, J. M., Lowrey, P. L., Turek, F. W., and Takahashi, J. S., Positional cloning of the mouse circadian clock gene, Cell, 89(4), 641-653, 1997.
-
(1997)
Cell
, vol.89
, Issue.4
, pp. 641-653
-
-
King, D.P.1
Zhao, Y.2
Sangoram, A.M.3
Wilsbacher, L.D.4
Tanaka, M.5
Antoch, M.P.6
Steeves, T.D.7
Vitaterna, M.H.8
Kornhauser, J.M.9
Lowrey, P.L.10
Turek, F.W.11
Takahashi, J.S.12
-
88
-
-
18844476167
-
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue
-
Antoch, M. P., Song, E. J., Chang, A. M., Vitaterna, M. H., Zhao, Y., Wilsbacher, L. D., Sangoram, A. M., King, D. P., Pinto, L. H., and Takahashi, J. S., Functional identification of the mouse circadian Clock gene by transgenic BAC rescue, Cell, 89(4), 655-667, 1997.
-
(1997)
Cell
, vol.89
, Issue.4
, pp. 655-667
-
-
Antoch, M.P.1
Song, E.J.2
Chang, A.M.3
Vitaterna, M.H.4
Zhao, Y.5
Wilsbacher, L.D.6
Sangoram, A.M.7
King, D.P.8
Pinto, L.H.9
Takahashi, J.S.10
-
89
-
-
0032531009
-
A clock polymorphism associated with human diurnal preference
-
Katzenberg, D., Young, T., Finn, L., Lin, L., King, D. P., Takahashi, J. S. and Mignot, E., A clock polymorphism associated with human diurnal preference, Sleep, 21(6), 569-576, 1998.
-
(1998)
Sleep
, vol.21
, Issue.6
, pp. 569-576
-
-
Katzenberg, D.1
Young, T.2
Finn, L.3
Lin, L.4
King, D.P.5
Takahashi, J.S.6
Mignot, E.7
-
90
-
-
0032486330
-
Role of the CLOCK protein in the mammalian circadian mechanism
-
Gekakis, N., Staknis, D., Nguyen, H. B., Davis, F. C., Wilsbacher, L. D., King, D. P., Takahashi, J. S., and Weitz, C. J., Role of the CLOCK protein in the mammalian circadian mechanism, Science, 280(5369), 1564-1569, 1998.
-
(1998)
Science
, vol.280
, Issue.5369
, pp. 1564-1569
-
-
Gekakis, N.1
Staknis, D.2
Nguyen, H.B.3
Davis, F.C.4
Wilsbacher, L.D.5
King, D.P.6
Takahashi, J.S.7
Weitz, C.J.8
-
91
-
-
0032486432
-
Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim
-
Darlington, T. K., Wager-Smith, K., Ceriani, M. F., Staknis, D., Gekakis, N., Steeves, T. D. L., Weitz, C. J., Takahashi, J. S., and Kay, S. A., Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim, Science, 280(5369), 1599-1603, 1998.
-
(1998)
Science
, vol.280
, Issue.5369
, pp. 1599-1603
-
-
Darlington, T.K.1
Wager-Smith, K.2
Ceriani, M.F.3
Staknis, D.4
Gekakis, N.5
Steeves, T.D.L.6
Weitz, C.J.7
Takahashi, J.S.8
Kay, S.A.9
-
92
-
-
0030756508
-
Defective platelet activation in G alpha(q)-deficient mice
-
Offermanns, S., Toombs, C. F., Hu, Y. H., and Simon, M. I., Defective platelet activation in G alpha(q)-deficient mice, Nature, 389(6647), 183-186, 1997.
-
(1997)
Nature
, vol.389
, Issue.6647
, pp. 183-186
-
-
Offermanns, S.1
Toombs, C.F.2
Hu, Y.H.3
Simon, M.I.4
-
93
-
-
0028980983
-
Developmentally expressed Ca(2+)-sensitive adenylyl cyclase activity is disrupted in the brains of type I adenylyl cyclase mutant mice
-
Villacres, E. C., Wu, Z., Hua, W., Nielsen, M. D., Watters, J. J., Yan, C., Beavo, J., and Storm, D. R., Developmentally expressed Ca(2+)-sensitive adenylyl cyclase activity is disrupted in the brains of type I adenylyl cyclase mutant mice, J. Biol. Chem., 270(24), 14352-14357, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.24
, pp. 14352-14357
-
-
Villacres, E.C.1
Wu, Z.2
Hua, W.3
Nielsen, M.D.4
Watters, J.J.5
Yan, C.6
Beavo, J.7
Storm, D.R.8
-
94
-
-
0031581108
-
Mice lacking the guanylyl cyclase C receptor are resistant to STa-induced intestinal secretion
-
Mann, E. A., Jump, M. L., Wu, J., Yee, E., and Giannella, R. A., Mice lacking the guanylyl cyclase C receptor are resistant to STa-induced intestinal secretion, Biochem. Biophys. Res. Commun., 239(2), 463-466, 1997.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.239
, Issue.2
, pp. 463-466
-
-
Mann, E.A.1
Jump, M.L.2
Wu, J.3
Yee, E.4
Giannella, R.A.5
-
95
-
-
0030779011
-
Disruption of the guanylyl cyclase-C gene leads to a paradoxical phenotype of viable but heat-stable enterotoxin-resistant mice
-
Schulz, S., Lopez, M. J., Kuhn, M., and Garbers, D. L., Disruption of the guanylyl cyclase-C gene leads to a paradoxical phenotype of viable but heat-stable enterotoxin-resistant mice, J. Clin. Invest., 100(6), 1590-1595, 1997.
-
(1997)
J. Clin. Invest.
, vol.100
, Issue.6
, pp. 1590-1595
-
-
Schulz, S.1
Lopez, M.J.2
Kuhn, M.3
Garbers, D.L.4
-
96
-
-
0028090302
-
The Trk family of neurotrophin receptors
-
Barbacid, M., The Trk family of neurotrophin receptors, J. Neurobiol., 25(11), 1386-1403, 1994.
-
(1994)
J. Neurobiol.
, vol.25
, Issue.11
, pp. 1386-1403
-
-
Barbacid, M.1
-
97
-
-
10544242967
-
Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function
-
Jaber, M., Koch, W. J., Rockman, H., Smith, B., Bond, R. A., Sulik, K. K., Ross, J., Jr., Lefkowitz, R. J., Caron, M. G., and Giros, B., Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function, Proc. Natl. Acad. Sci. U.S.A., 93(23), 12974-12979, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.23
, pp. 12974-12979
-
-
Jaber, M.1
Koch, W.J.2
Rockman, H.3
Smith, B.4
Bond, R.A.5
Sulik, K.K.6
Ross Jr., J.7
Lefkowitz, R.J.8
Caron, M.G.9
Giros, B.10
-
98
-
-
0027176228
-
Constitutive activation of Src family kineses in mouse embryos that lack Csk
-
Nada, S., Yagi, T., Takeda, H., Tokunaga, T., Nakagawa, H., Ikawa, Y., Okada, M., and Aizawa, S., Constitutive activation of Src family kineses in mouse embryos that lack Csk, Cell, 73(6), 1125-1135, 1993.
-
(1993)
Cell
, vol.73
, Issue.6
, pp. 1125-1135
-
-
Nada, S.1
Yagi, T.2
Takeda, H.3
Tokunaga, T.4
Nakagawa, H.5
Ikawa, Y.6
Okada, M.7
Aizawa, S.8
-
99
-
-
0030452310
-
Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II
-
Pfeifer, A., Aszodi, A., Seidler, U., Ruth, P., Hofmann, F., and Fassler, R., Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II, Science, 274(5295), 2082-2086, 1996.
-
(1996)
Science
, vol.274
, Issue.5295
, pp. 2082-2086
-
-
Pfeifer, A.1
Aszodi, A.2
Seidler, U.3
Ruth, P.4
Hofmann, F.5
Fassler, R.6
-
100
-
-
9044233633
-
Impaired hippocampal plasticity in mice lacking the Cbetal catalytic subunit of cAMP-dependent protein kinase
-
Qi, M., Zhuo, M., Skalhegg, B. S., Brandon, E. P., Kandel, E. R., McKnight, G. S., and Idzerda, R. L., Impaired hippocampal plasticity in mice lacking the Cbetal catalytic subunit of cAMP-dependent protein kinase, Proc. Natl. Acad. Sci. U.S.A., 93(4), 1571-1576, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.4
, pp. 1571-1576
-
-
Qi, M.1
Zhuo, M.2
Skalhegg, B.S.3
Brandon, E.P.4
Kandel, E.R.5
McKnight, G.S.6
Idzerda, R.L.7
-
101
-
-
0026742451
-
Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice
-
Silva, A. J., Paylor, R., Wehner, J. M., and Tonegawa, S., Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice, Science, 257(5067), 206-211, 1992.
-
(1992)
Science
, vol.257
, Issue.5067
, pp. 206-211
-
-
Silva, A.J.1
Paylor, R.2
Wehner, J.M.3
Tonegawa, S.4
-
102
-
-
0029115393
-
Mice lacking tissue nonspecific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6
-
Waymire, K. G., Mahuren, J. D., Jaje, J. M., Guilarte, T. R., Coburn, S. P., and MacGregor, G. R., Mice lacking tissue nonspecific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6, Nat. Genet., 11(1), 45-51, 1995.
-
(1995)
Nat. Genet.
, vol.11
, Issue.1
, pp. 45-51
-
-
Waymire, K.G.1
Mahuren, J.D.2
Jaje, J.M.3
Guilarte, T.R.4
Coburn, S.P.5
MacGregor, G.R.6
-
103
-
-
0031031229
-
Deficient LAR expression decreases basal fore-brain cholinergic neuronal size and hippocampal cholinergic innervation
-
Yeo, T. T., Yang, T., Massa, S. M., Zhang, J. S., Honkaniemi, J., Butcher, L. L., and Longo, F. M., Deficient LAR expression decreases basal fore-brain cholinergic neuronal size and hippocampal cholinergic innervation, J. Neurosci. Res., 47(3), 348-360, 1997.
-
(1997)
J. Neurosci. Res.
, vol.47
, Issue.3
, pp. 348-360
-
-
Yeo, T.T.1
Yang, T.2
Massa, S.M.3
Zhang, J.S.4
Honkaniemi, J.5
Butcher, L.L.6
Longo, F.M.7
-
104
-
-
0030771361
-
Role of subunit diversity in signaling by heterotrimeric G proteins
-
Hildebrandt, J. D., Role of subunit diversity in signaling by heterotrimeric G proteins, Biochem. Pharmacol., 54(3), 325-339, 1997.
-
(1997)
Biochem. Pharmacol.
, vol.54
, Issue.3
, pp. 325-339
-
-
Hildebrandt, J.D.1
-
105
-
-
0025194361
-
GO is a major growth cone protein subject to regulation by GAP-43
-
Strittmatter, S. M., Valenzuela, D., Kennedy, T. E., Neer, E. J. and Fishman, M. C., GO is a major growth cone protein subject to regulation by GAP-43, Nature, 344(6269), 836-841, 1990.
-
(1990)
Nature
, vol.344
, Issue.6269
, pp. 836-841
-
-
Strittmatter, S.M.1
Valenzuela, D.2
Kennedy, T.E.3
Neer, E.J.4
Fishman, M.C.5
-
106
-
-
0031055325
-
G alpha(o) is necessary for muscarinic regulation of Ca2+ channels in mouse heart
-
Valenzuela, D., Han, X., Mende, U., Fankhauser, C., Mashimo, H., Huang, P., Pfeffer, J., Neer, E. J., and Fishman, M. C., G alpha(o) is necessary for muscarinic regulation of Ca2+ channels in mouse heart, Proc. Natl. Acad. Sci. U.S.A., 94(5), 1727-1732, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.5
, pp. 1727-1732
-
-
Valenzuela, D.1
Han, X.2
Mende, U.3
Fankhauser, C.4
Mashimo, H.5
Huang, P.6
Pfeffer, J.7
Neer, E.J.8
Fishman, M.C.9
-
107
-
-
11744265275
-
Multiple neurological abnormalities in mice deficient in the g protein G(0)
-
Jiang, M. S., Gold, M. S., Boulay, G., Spicher, K., Peyton, M., Brabet, P., Srinivasan, Y., Rudolph, U., Ellison, G., and Birnbaumer, L., Multiple neurological abnormalities in mice deficient in the g protein G(0), Proc. Natl. Acad. Sci. U.S.A., 95(6), 3269-3274 1998.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, Issue.6
, pp. 3269-3274
-
-
Jiang, M.S.1
Gold, M.S.2
Boulay, G.3
Spicher, K.4
Peyton, M.5
Brabet, P.6
Srinivasan, Y.7
Rudolph, U.8
Ellison, G.9
Birnbaumer, L.10
-
108
-
-
0028853240
-
Neuronal path-finding is abnormal in mice lacking the neuronal growth cone protein GAP-43
-
Strittmatter, S. M., Fankhauser, C., Huang, P. L., Mashimo, H., and Fishman, M. C., Neuronal path-finding is abnormal in mice lacking the neuronal growth cone protein GAP-43, Cell, 80(3), 445-452, 1995.
-
(1995)
Cell
, vol.80
, Issue.3
, pp. 445-452
-
-
Strittmatter, S.M.1
Fankhauser, C.2
Huang, P.L.3
Mashimo, H.4
Fishman, M.C.5
-
109
-
-
0031471709
-
Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A(2)
-
Bonventre, J. V., Huang, Z. H., Taheri, M. R., Oleary, E., Li, E., Moskowitz, M. A., and Sapirstein, A., Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A(2), Nature, 390(6660), 622-625, 1997.
-
(1997)
Nature
, vol.390
, Issue.6660
, pp. 622-625
-
-
Bonventre, J.V.1
Huang, Z.H.2
Taheri, M.R.3
Oleary, E.4
Li, E.5
Moskowitz, M.A.6
Sapirstein, A.7
-
110
-
-
0029740113
-
Retinal degeneration in mice lacking the gamma subunit of the rod cGMP phosphodiesterase
-
Tsang, S. H., Gouras, P., Yamashita, C. K., Kjeldbye, H., Fisher, J., Farber, D. B., and Goff, S. P., Retinal degeneration in mice lacking the gamma subunit of the rod cGMP phosphodiesterase, Science, 272(5264), 1026-1029, 1996.
-
(1996)
Science
, vol.272
, Issue.5264
, pp. 1026-1029
-
-
Tsang, S.H.1
Gouras, P.2
Yamashita, C.K.3
Kjeldbye, H.4
Fisher, J.5
Farber, D.B.6
Goff, S.P.7
-
112
-
-
0030273253
-
General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel
-
Brunet, L. J., Gold, G. H. and Ngai, J., General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel, Neuron, 17(4), 681-693, 1996.
-
(1996)
Neuron
, vol.17
, Issue.4
, pp. 681-693
-
-
Brunet, L.J.1
Gold, G.H.2
Ngai, J.3
-
113
-
-
0028171296
-
Alpha 9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells
-
Elgoyhen, A.B., Johnson, D.S., Boulter, J., Vetter, D. E., and Heinemann, S., Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells, Cell, 79 705-715, 1994.
-
(1994)
Cell
, vol.79
, pp. 705-715
-
-
Elgoyhen, A.B.1
Johnson, D.S.2
Boulter, J.3
Vetter, D.E.4
Heinemann, S.5
-
114
-
-
0343255649
-
Altered cochlear efferent fiber innervation and acoustic startle reflex in alpha9 nAChR subunit knockout mice
-
Vetter, D. E., Stitzel, J. A., Mann, J., Elgoyhen, A. B., Saffiote, J., Barhanin, J., Collins, A. C., and Heinemann, S. F., Altered cochlear efferent fiber innervation and acoustic startle reflex in alpha9 nAChR subunit knockout mice, Soc. Neurosci. Abstr., 23(1-2), 732, 1997.
-
(1997)
Soc. Neurosci. Abstr.
, vol.23
, Issue.1-2
, pp. 732
-
-
Vetter, D.E.1
Stitzel, J.A.2
Mann, J.3
Elgoyhen, A.B.4
Saffiote, J.5
Barhanin, J.6
Collins, A.C.7
Heinemann, S.F.8
-
115
-
-
13344250473
-
Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor
-
Matsumoto, M., Nakagawa, T., Inoue, T., Nagata, E., Tanaka, K., Takano, H., Minowa, O., Kuno, J., Sakakibara, S., Yamada, M., Yoneshima, H., Miyawaki, A., Fukuuchi, Y., Furuichi, T., Okano, H., Mikoshiba, K., and Noda, T., Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor, Nature, 379(6561), 168-171, 1996.
-
(1996)
Nature
, vol.379
, Issue.6561
, pp. 168-171
-
-
Matsumoto, M.1
Nakagawa, T.2
Inoue, T.3
Nagata, E.4
Tanaka, K.5
Takano, H.6
Minowa, O.7
Kuno, J.8
Sakakibara, S.9
Yamada, M.10
Yoneshima, H.11
Miyawaki, A.12
Fukuuchi, Y.13
Furuichi, T.14
Okano, H.15
Mikoshiba, K.16
Noda, T.17
-
116
-
-
0029935712
-
Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice
-
Hummler, E., Barker, P., Gatzy, J., Beermann, F., Verdumo, C., Schmidt, A., Boucher, R., and Rossier, B. C., Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice, Nat. Genet., 12(3),325-328, 1996.
-
(1996)
Nat. Genet.
, vol.12
, Issue.3
, pp. 325-328
-
-
Hummler, E.1
Barker, P.2
Gatzy, J.3
Beermann, F.4
Verdumo, C.5
Schmidt, A.6
Boucher, R.7
Rossier, B.C.8
-
117
-
-
0028934859
-
+ channel proteins
-
+ channel proteins, Nature, 374, 135-141, 1995.
-
(1995)
Nature
, vol.374
, pp. 135-141
-
-
Krapivinsky, G.1
Gordon, E.2
Wickman, K.3
Velimirovic, B.4
Krapivinsky, L.5
Clapham, D.6
-
120
-
-
0029015089
-
The inward rectifier potassium channel family
-
Doupnik, C., Davidson, N., and Lester, H., The inward rectifier potassium channel family, Curr. Opin. Neurobiol., 5, 268-277, 1995.
-
(1995)
Curr. Opin. Neurobiol.
, vol.5
, pp. 268-277
-
-
Doupnik, C.1
Davidson, N.2
Lester, H.3
-
121
-
-
0024730134
-
Drug receptors and the inhibition of nerve cells
-
North, R., Drug receptors and the inhibition of nerve cells, Br. J. Pharmacol., 98, 13-28, 1989.
-
(1989)
Br. J. Pharmacol.
, vol.98
, pp. 13-28
-
-
North, R.1
-
122
-
-
0029944453
-
+ channel mRNAs are differentially expressed in the adult rat brain
-
+ channel mRNAs are differentially expressed in the adult rat brain, J. Neurosci., 16, 3559-3570, 1996.
-
(1996)
J. Neurosci.
, vol.16
, pp. 3559-3570
-
-
Karschin, C.1
Dissmann, E.2
Stuhmer, W.3
Karschin, A.4
-
123
-
-
0030861479
-
An immunocytochemical study on the distribution of two G-protein-gated inward rectifier potassium channels (GIRK2 and GIRK4) in the adult rat brain
-
Murer, G., Adelbrecht, C., Lauritzen, I., Lesage, F., Lazdunski, M., Agid, Y., and Raisman-Vozari, R., An immunocytochemical study on the distribution of two G-protein-gated inward rectifier potassium channels (GIRK2 and GIRK4) in the adult rat brain, Neuroscience, 80, 345-357, 1997.
-
(1997)
Neuroscience
, vol.80
, pp. 345-357
-
-
Murer, G.1
Adelbrecht, C.2
Lauritzen, I.3
Lesage, F.4
Lazdunski, M.5
Agid, Y.6
Raisman-Vozari, R.7
-
124
-
-
0031909974
-
Abnormal heart rate regulation in GIRK4 knockout mice
-
Wickman, K., Nemec, J., Gendler, S. J., and Clapham, D. E., Abnormal heart rate regulation in GIRK4 knockout mice, Neuron, 20(1), 103-114, 1998.
-
(1998)
Neuron
, vol.20
, Issue.1
, pp. 103-114
-
-
Wickman, K.1
Nemec, J.2
Gendler, S.J.3
Clapham, D.E.4
-
125
-
-
0027368451
-
Modulation of synaptic transmission and long-term potentiation: Effects on paired-pulse facilitation and EPSC variance in the CA1 region of the hippocampus
-
Manabe, T., Wyllie, D., Perkel, D., and Nicoll, R., Modulation of synaptic transmission and long-term potentiation: effects on paired-pulse facilitation and EPSC variance in the CA1 region of the hippocampus, J. Neurophysiol., 70, 1451-1459, 1993.
-
(1993)
J. Neurophysiol.
, vol.70
, pp. 1451-1459
-
-
Manabe, T.1
Wyllie, D.2
Perkel, D.3
Nicoll, R.4
-
126
-
-
0024600340
-
Short-term synaptic plasticity
-
Zucker, R., Short-term synaptic plasticity, Annu. Rev. Neurosci., 12, 13-31, 1989.
-
(1989)
Annu. Rev. Neurosci.
, vol.12
, pp. 13-31
-
-
Zucker, R.1
-
127
-
-
0031016163
-
+ channel GIRK2
-
+ channel GIRK2, Proc. Natl. Acad. Sci. U.S.A., 94, 923-927, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 923-927
-
-
Signorini, S.1
Liao, Y.2
Duncan, S.3
Jan, L.4
Stoffel, M.5
-
128
-
-
0003982199
-
Pleiotropic effects of a disrupted K+ channel gene: Reduced body weight, impaired motor skill, and muscle contraction, but no seizures
-
Ho, C. S., Grange, R. W., and Joho, R. H., Pleiotropic effects of a disrupted K+ channel gene: reduced body weight, impaired motor skill, and muscle contraction, but no seizures, Proc. Natl. Acad. Sci.. U.S.A., 94(4), 1533-1538, 1997.
-
(1997)
Proc. Natl. Acad. Sci.. U.S.A.
, vol.94
, Issue.4
, pp. 1533-1538
-
-
Ho, C.S.1
Grange, R.W.2
Joho, R.H.3
-
129
-
-
0030870509
-
Deficient cation channel regulation in neurons from mice with targeted disruption of the extracellular Ca2+-sensing receptor gene
-
Ye, C. P., Hopao, C. L., Kanazirska, M., Quinn, S., Seidman, C. E., Seidman, G., Brown, E. M., and Vassilev, P. M., Deficient cation channel regulation in neurons from mice with targeted disruption of the extracellular Ca2+-sensing receptor gene, Brain Res. Bull., 44(1), 75-84, 1997.
-
(1997)
Brain Res. Bull.
, vol.44
, Issue.1
, pp. 75-84
-
-
Ye, C.P.1
Hopao, C.L.2
Kanazirska, M.3
Quinn, S.4
Seidman, C.E.5
Seidman, G.6
Brown, E.M.7
Vassilev, P.M.8
-
130
-
-
0029764770
-
Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB
-
Maldonado, R., Blendy, J. A., Tzavara, E., Gass, P., Roques, B. P., Hanoune, J., and Schutz, G., Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB, Science, 273(5275), 657-659, 1996.
-
(1996)
Science
, vol.273
, Issue.5275
, pp. 657-659
-
-
Maldonado, R.1
Blendy, J.A.2
Tzavara, E.3
Gass, P.4
Roques, B.P.5
Hanoune, J.6
Schutz, G.7
-
131
-
-
0028071507
-
Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein
-
Bourtchuladze, R., Frenguelli, B., Blendy, J., Cioffi, D., Schutz, G., and Silva, A. J., Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein, Cell, 79(1), 59-68, 1994.
-
(1994)
Cell
, vol.79
, Issue.1
, pp. 59-68
-
-
Bourtchuladze, R.1
Frenguelli, B.2
Blendy, J.3
Cioffi, D.4
Schutz, G.5
Silva, A.J.6
-
132
-
-
0031465159
-
Defective limbic system in mice lacking the tailless gene
-
Monaghan, A. P., Bock, D., Gass, P., Schwager, A., Wolfer, D. P., Lipp, H. P., and Schutz, G., Defective limbic system in mice lacking the tailless gene, Nature, 390(6659), 515-517, 1997.
-
(1997)
Nature
, vol.390
, Issue.6659
, pp. 515-517
-
-
Monaghan, A.P.1
Bock, D.2
Gass, P.3
Schwager, A.4
Wolfer, D.P.5
Lipp, H.P.6
Schutz, G.7
-
133
-
-
0029922536
-
Null mutation of c-fos impairs structural and functional plasticities in the kindling model of epilepsy
-
Watanabe, Y., Johnson, R. S., Butler, L. S., Binder, D. K., Spiegelman, B. M., Papaioannou, V. E., and McNamara, J. O., Null mutation of c-fos impairs structural and functional plasticities in the kindling model of epilepsy, J. Neurosci., 16(12), 3827-3836, 1996.
-
(1996)
J. Neurosci.
, vol.16
, Issue.12
, pp. 3827-3836
-
-
Watanabe, Y.1
Johnson, R.S.2
Butler, L.S.3
Binder, D.K.4
Spiegelman, B.M.5
Papaioannou, V.E.6
McNamara, J.O.7
-
134
-
-
0028302438
-
Behavioral assessment of c-fos mutant mice
-
Paylor, R., Johnson, R. S., Papaioannou, V., Spiegelman, B. M., and Wehner, J. M., Behavioral assessment of c-fos mutant mice, Brain Res., 651(1-2), 275-282, 1994.
-
(1994)
Brain Res.
, vol.651
, Issue.1-2
, pp. 275-282
-
-
Paylor, R.1
Johnson, R.S.2
Papaioannou, V.3
Spiegelman, B.M.4
Wehner, J.M.5
-
135
-
-
0030602817
-
A defect in nurturing in mice lacking the immediate early gene fosB
-
Brown, J. R., Ye, H., Bronson, R. T., Dikkes, P., and Greenberg, M. E., A defect in nurturing in mice lacking the immediate early gene fosB, Cell, 86(2), 297-309, 1996.
-
(1996)
Cell
, vol.86
, Issue.2
, pp. 297-309
-
-
Brown, J.R.1
Ye, H.2
Bronson, R.T.3
Dikkes, P.4
Greenberg, M.E.5
-
136
-
-
0030885427
-
FosB mutant mice: Loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects
-
Hiroi, N., Brown, J. R., Haile, C. N., Ye, H., Greenberg, M. E., and Nestler, E. J., FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects, Proc. Natl. Acad. Sci. U.S.A., 94(19), 10397-10402, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.19
, pp. 10397-10402
-
-
Hiroi, N.1
Brown, J.R.2
Haile, C.N.3
Ye, H.4
Greenberg, M.E.5
Nestler, E.J.6
-
137
-
-
0027404604
-
The molecular machinery for secretion is conserved from yeast to neurons
-
Bennett, M. K. and Scheller, R. H., The molecular machinery for secretion is conserved from yeast to neurons, Proc. Natl. Acad. Sci. U.S.A., 90(7), 2559-2563, 1993.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, Issue.7
, pp. 2559-2563
-
-
Bennett, M.K.1
Scheller, R.H.2
-
138
-
-
0030051050
-
Synaptic vesicle biogenesis, docking, and fusion: A molecular description
-
Calakos, N. and Scheller, R. H., Synaptic vesicle biogenesis, docking, and fusion: a molecular description, Physiol. Rev., 76(1), 1-29, 1996.
-
(1996)
Physiol. Rev.
, vol.76
, Issue.1
, pp. 1-29
-
-
Calakos, N.1
Scheller, R.H.2
-
139
-
-
0027402975
-
Synaptic vesicle phosphoproteins and regulation of synaptic function
-
Greengard, P., Valtorta, F., Czernik, A. J., and Benfenati, F., Synaptic vesicle phosphoproteins and regulation of synaptic function, Science, 259(5096), 780-785, 1993.
-
(1993)
Science
, vol.259
, Issue.5096
, pp. 780-785
-
-
Greengard, P.1
Valtorta, F.2
Czernik, A.J.3
Benfenati, F.4
-
140
-
-
0028216869
-
Synaptic vesicles and exocytosis
-
Jahn, R. and Sudhof, T. C., Synaptic vesicles and exocytosis, Annu. Rev. Neurosci., 17, 219-246, 1994.
-
(1994)
Annu. Rev. Neurosci.
, vol.17
, pp. 219-246
-
-
Jahn, R.1
Sudhof, T.C.2
-
141
-
-
0031050921
-
Multiple overlapping processes underlying short-term synaptic enhancement
-
Fisher, S. A., Fischer, T. M., and Carew, T. J., Multiple overlapping processes underlying short-term synaptic enhancement, Trends Neurosci., 20(4), 170-177, 1997.
-
(1997)
Trends Neurosci.
, vol.20
, Issue.4
, pp. 170-177
-
-
Fisher, S.A.1
Fischer, T.M.2
Carew, T.J.3
-
142
-
-
0032516032
-
A third member of the synapsin gene family
-
Kao, H. T., Porton, B., Czernik, A. J., Feng, J., Yiu, G., Haring, M., Benfenati, F., and Greengard, P., A third member of the synapsin gene family, Proc. Natl. Acad. Sci. U.S.A., 95(8), 4667-4672, 1998.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, Issue.8
, pp. 4667-4672
-
-
Kao, H.T.1
Porton, B.2
Czernik, A.J.3
Feng, J.4
Yiu, G.5
Haring, M.6
Benfenati, F.7
Greengard, P.8
-
143
-
-
0027482675
-
Short-term synaptic plasticity is altered in mice lacking synapsin I
-
Rosahl, T. W., Geppert, M., Spillane, D., Herz, J., Hammer, R. E., Malenka, R. C., and Sudhof, T. C., Short-term synaptic plasticity is altered in mice lacking synapsin I, Cell, 75(4), 661-670, 1993.
-
(1993)
Cell
, vol.75
, Issue.4
, pp. 661-670
-
-
Rosahl, T.W.1
Geppert, M.2
Spillane, D.3
Herz, J.4
Hammer, R.E.5
Malenka, R.C.6
Sudhof, T.C.7
-
144
-
-
0029024135
-
Essential functions of synapsins I and II in synaptic vesicle regulation
-
Rosahl, T. W., Spillane, D., Missler, M., Herz, J., Selig, D. K., Wolff, J. R., Hammer, R. E., Malenka, R. C., and Sudhof, T. C., Essential functions of synapsins I and II in synaptic vesicle regulation, Nature, 375(6531), 488-493, 1995.
-
(1995)
Nature
, vol.375
, Issue.6531
, pp. 488-493
-
-
Rosahl, T.W.1
Spillane, D.2
Missler, M.3
Herz, J.4
Selig, D.K.5
Wolff, J.R.6
Hammer, R.E.7
Malenka, R.C.8
Sudhof, T.C.9
-
145
-
-
0028788822
-
Long-term potentiation in mice lacking synapsins
-
Spillane, D. M., Rosahl, T. W., Sudhof, T. C., and Malenka, R. C., Long-term potentiation in mice lacking synapsins, Neuropharmacology, 34(11), 1573-1579, 1995.
-
(1995)
Neuropharmacology
, vol.34
, Issue.11
, pp. 1573-1579
-
-
Spillane, D.M.1
Rosahl, T.W.2
Sudhof, T.C.3
Malenka, R.C.4
-
146
-
-
12644312203
-
Impaired learning in mice with abnormal short-lived plasticity
-
Silva, A. J., Rosahl, T. W., Chapman, P. F., Marowitz, Z., Friedman, E., Frankland, P. W., Cestari, V., Cioffi, D., Sudhof, T. C., and Bourtchuladze, R., Impaired learning in mice with abnormal short-lived plasticity, Curr. Biol, 6(11), 1509-1518, 1996.
-
(1996)
Curr. Biol
, vol.6
, Issue.11
, pp. 1509-1518
-
-
Silva, A.J.1
Rosahl, T.W.2
Chapman, P.F.3
Marowitz, Z.4
Friedman, E.5
Frankland, P.W.6
Cestari, V.7
Cioffi, D.8
Sudhof, T.C.9
Bourtchuladze, R.10
-
147
-
-
0029022960
-
Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice
-
Chin, L. S., Li, L., Ferreira, A., Kosik, K. S., and Greengard, P., Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice, Proc. Natl. Acad. Sci. U.S.A., 92(20), 9230-9234, 1995.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, Issue.20
, pp. 9230-9234
-
-
Chin, L.S.1
Li, L.2
Ferreira, A.3
Kosik, K.S.4
Greengard, P.5
-
148
-
-
0031917238
-
Distinct roles of synapsin I and synapsin II during neuronal development
-
Ferreira, A., Chin, L. S., Li, L., Lanier, L. M., Kosik, K. S., and Greengard, P., Distinct roles of synapsin I and synapsin II during neuronal development, Mol. Med., 4(1), 22-28, 1998.
-
(1998)
Mol. Med.
, vol.4
, Issue.1
, pp. 22-28
-
-
Ferreira, A.1
Chin, L.S.2
Li, L.3
Lanier, L.M.4
Kosik, K.S.5
Greengard, P.6
-
149
-
-
0029781368
-
Synaptic vesicle recycling in synapsin I knock-out mice
-
Ryan, T. A., Li, L., Chin, L. S., Greengard, P., and Smith, S. J., Synaptic vesicle recycling in synapsin I knock-out mice, J. Cell. Biol., 134(5), 1219-1227, 1996.
-
(1996)
J. Cell. Biol.
, vol.134
, Issue.5
, pp. 1219-1227
-
-
Ryan, T.A.1
Li, L.2
Chin, L.S.3
Greengard, P.4
Smith, S.J.5
-
150
-
-
0028343430
-
The role of Rab3A in neurotransmitter release
-
Geppert, M., Bolshakov, V. Y., Siegelbaum, S. A., Takei, K., De Camilli, P., Hammer, R. E., and Sudhof, T. C., The role of Rab3A in neurotransmitter release, Nature, 369(6480), 493-497, 1994.
-
(1994)
Nature
, vol.369
, Issue.6480
, pp. 493-497
-
-
Geppert, M.1
Bolshakov, V.Y.2
Siegelbaum, A.S.3
Takei, K.4
De Camilli, P.5
Hammer, R.E.6
Sudhof, T.C.7
-
151
-
-
0030791511
-
Rab3A is essential for mossy fibre long-term potentiation in the hippocampus
-
Castillo, P. E., Janz, R., Sudhof, T. C., Tzounopoulos, T., Malenka, R. C., and Nicoll, R. A., Rab3A is essential for mossy fibre long-term potentiation in the hippocampus, Nature, 388(6642), 590-593, 1997.
-
(1997)
Nature
, vol.388
, Issue.6642
, pp. 590-593
-
-
Castillo, P.E.1
Janz, R.2
Sudhof, T.C.3
Tzounopoulos, T.4
Malenka, R.C.5
Nicoll, R.A.6
-
152
-
-
0030980279
-
The small GTP-binding protein Rab3a regulates a late step in synaptic vesicle fusion
-
Geppert, M., Goda, Y., Stevens, C. F., and Sudhof, T. C., The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion, Nature, 387(6635), 810-814, 1997.
-
(1997)
Nature
, vol.387
, Issue.6635
, pp. 810-814
-
-
Geppert, M.1
Goda, Y.2
Stevens, C.F.3
Sudhof, T.C.4
-
153
-
-
0028061861
-
Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse
-
Geppert, M., Goda, Y., Hammer, R. E., Li, C., Kosahl, T. W., Stevens, C. F., and Sudhof, T. C., Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse, Cell, 79(4), 717-727, 1994.
-
(1994)
Cell
, vol.79
, Issue.4
, pp. 717-727
-
-
Geppert, M.1
Goda, Y.2
Hammer, R.E.3
Li, C.4
Kosahl, T.W.5
Stevens, C.F.6
Sudhof, T.C.7
-
154
-
-
0028839811
-
Mice lacking synaptophysin reproduce and form typical synaptic vesicles
-
Eshkind, L. G. and Leube, R. E., Mice lacking synaptophysin reproduce and form typical synaptic vesicles, Cell. Tissue Res., 282(3), 423-433, 1995.
-
(1995)
Cell. Tissue Res.
, vol.282
, Issue.3
, pp. 423-433
-
-
Eshkind, L.G.1
Leube, R.E.2
-
155
-
-
0029899866
-
Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release
-
McMahon, H. T., Bolshakov, V. Y., Janz, R., Hammer, R. E., Siegelbaum, S. A., and Sudhof, T. C., Synaptophysin, a major synaptic vesicle protein, is not essential for neurotransmitter release, Proc. Natl. Acad. Sci. U.S.A., 93(10), 4760-4764, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.10
, pp. 4760-4764
-
-
McMahon, H.T.1
Bolshakov, V.Y.2
Janz, R.3
Hammer, R.E.4
Siegelbaum, S.A.5
Sudhof, T.C.6
-
156
-
-
0030976929
-
Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration
-
Peghini, P., Janzen, J., and Stoffel, W., Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration, EMBO J., 16(13), 3822-3832, 1997.
-
(1997)
EMBO J.
, vol.16
, Issue.13
, pp. 3822-3832
-
-
Peghini, P.1
Janzen, J.2
Stoffel, W.3
-
157
-
-
0030812843
-
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1
-
Tanaka, K., Watase, K., Manabe, T., Yamada, K., Watanabe, M., Takahashi, K., Iwama, H., Nishikawa, T., Ichihara, N., Kikuchi, T., Okuyama, S., Kawashima, N., Hori, S., Takimoto, M., and Wada, K., Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1, Science, 276(5319), 1699-1702, 1997.
-
(1997)
Science
, vol.276
, Issue.5319
, pp. 1699-1702
-
-
Tanaka, K.1
Watase, K.2
Manabe, T.3
Yamada, K.4
Watanabe, M.5
Takahashi, K.6
Iwama, H.7
Nishikawa, T.8
Ichihara, N.9
Kikuchi, T.10
Okuyama, S.11
Kawashima, N.12
Hori, S.13
Takimoto, M.14
Wada, K.15
-
158
-
-
13344286293
-
Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
-
Rothstein, J. D., Dykes-Hoberg, M., Pardo, C. A., Bristol, L. A., Jin, L., Kuncl, R. W., Kanal, Y., Hediger, M. A., Wang, Y., Schielke, J. P., and Welty, D. F., Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate, Neuron, 16(3), 675-686, 1996.
-
(1996)
Neuron
, vol.16
, Issue.3
, pp. 675-686
-
-
Rothstein, J.D.1
Dykes-Hoberg, M.2
Pardo, C.A.3
Bristol, L.A.4
Jin, L.5
Kuncl, R.W.6
Kanal, Y.7
Hediger, M.A.8
Wang, Y.9
Schielke, J.P.10
Welty, D.F.11
-
159
-
-
0028173680
-
Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice
-
Li, Y., Erzurumlu, R. S., Chen, C., Jhaveri, S., and Tonegawa, S., Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice, Cell, 76(3), 427-437, 1994.
-
(1994)
Cell
, vol.76
, Issue.3
, pp. 427-437
-
-
Li, Y.1
Erzurumlu, R.S.2
Chen, C.3
Jhaveri, S.4
Tonegawa, S.5
-
160
-
-
0028030468
-
Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death
-
Forrest, D., Yuzaki, M., Soares, H. D., Ng, L., Luk, D. C., Sheng, M.,
-
(1994)
Neuron
, vol.13
, Issue.2
, pp. 325-338
-
-
Forrest, D.1
Yuzaki, M.2
Soares, H.D.3
Ng, L.4
Luk, D.C.5
Sheng, M.6
Stewart, C.L.7
Morgan, J.I.8
Connor, J.A.9
Curran, T.10
-
161
-
-
0029812141
-
Motor discoordination results from combined gene disruption of the NMDA receptor NR2A and NR2C subunits, but not from single disruption of the NR2A or NR2C subunit
-
Kadotani, H., Hirano, T., Masugi, M., Nakamura, K., Nakao, K., Katsuki, M., and Nakanishi, S., Motor discoordination results from combined gene disruption of the NMDA receptor NR2A and NR2C subunits, but not from single disruption of the NR2A or NR2C subunit, J. Neurosci., 16(24), 7859-7867, 1996.
-
(1996)
J. Neurosci.
, vol.16
, Issue.24
, pp. 7859-7867
-
-
Kadotani, H.1
Hirano, T.2
Masugi, M.3
Nakamura, K.4
Nakao, K.5
Katsuki, M.6
Nakanishi, S.7
-
162
-
-
0030053773
-
Age-dependent reduction of hippocampal LTP in mice lacking N-methyl-D-aspartate receptor epsilon 1 subunit
-
Ito, I., Sakimura, K., Mishina, M., and Sugiyama, H., Age-dependent reduction of hippocampal LTP in mice lacking N-methyl-D-aspartate receptor epsilon 1 subunit, Neurosci. Lett., 203(1), 69-71, 1996.
-
(1996)
Neurosci. Lett.
, vol.203
, Issue.1
, pp. 69-71
-
-
Ito, I.1
Sakimura, K.2
Mishina, M.3
Sugiyama, H.4
-
163
-
-
0029143338
-
Reduced spontaneous activity of mice defective in the epsilon 4 subunit of the NMDA receptor channel
-
Ikeda, K., Araki, K., Takayama, C., Inoue, Y., Yagi, T., Aizawa, S., and Mishina, M., Reduced spontaneous activity of mice defective in the epsilon 4 subunit of the NMDA receptor channel, Brain Res. Mol. Brain Res., 33(1), 61-71, 1995.
-
(1995)
Brain Res. Mol. Brain Res.
, vol.33
, Issue.1
, pp. 61-71
-
-
Ikeda, K.1
Araki, K.2
Takayama, C.3
Inoue, Y.4
Yagi, T.5
Aizawa, S.6
Mishina, M.7
-
164
-
-
13344261412
-
Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice
-
Kutsuwada, T., Sakimura, K., Manabe, T., Takayama, C., Katakura, N., Kushiya, E., Natsume, R., Watanabe, M., Inoue, Y., Yagi, T., Aizawa, S., Arakawa, M., Takahashi, T., Nakamura, Y., Mori, H., and Mishina, M., Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice, Neuron, 16(2), 333-344 1996.
-
(1996)
Neuron
, vol.16
, Issue.2
, pp. 333-344
-
-
Kutsuwada, T.1
Sakimura, K.2
Manabe, T.3
Takayama, C.4
Katakura, N.5
Kushiya, E.6
Natsume, R.7
Watanabe, M.8
Inoue, Y.9
Yagi, T.10
Aizawa, S.11
Arakawa, M.12
Takahashi, T.13
Nakamura, Y.14
Mori, H.15
Mishina, M.16
-
165
-
-
0032536495
-
Attenuation of focal cerebral infarct in mice lacking NMDA receptor subunit NR2C
-
Kadotani, H., Namura, S., Katsuura, G., Terashima, T., and Kikuchi, H., Attenuation of focal cerebral infarct in mice lacking NMDA receptor subunit NR2C, Neuroreport, 9(3), 471-475 1998.
-
(1998)
Neuroreport
, vol.9
, Issue.3
, pp. 471-475
-
-
Kadotani, H.1
Namura, S.2
Katsuura, G.3
Terashima, T.4
Kikuchi, H.5
-
166
-
-
0032559283
-
Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo
-
Sprengel, R., Suchanek, B., Amico, C., Brusa, R., Burnashev, N., Rozov, A., Hvalby, O., Jensen, V., Paulsen, O., Andersen, P., Kim, J. J., Thompson, R. F., Sun, W., Webster, L. C., Grant, S. G., Eilers, J., Konnerth, A., Li, J., McNamara, J. O., and Seeburg, P. H., Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo, Cell, 92(2), 279-289, 1998.
-
(1998)
Cell
, vol.92
, Issue.2
, pp. 279-289
-
-
Sprengel, R.1
Suchanek, B.2
Amico, C.3
Brusa, R.4
Burnashev, N.5
Rozov, A.6
Hvalby, O.7
Jensen, V.8
Paulsen, O.9
Andersen, P.10
Kim, J.J.11
Thompson, R.F.12
Sun, W.13
Webster, L.C.14
Grant, S.G.15
Eilers, J.16
Konnerth, A.17
Li, J.18
McNamara, J.O.19
Seeburg, P.H.20
more..
-
167
-
-
0029610443
-
Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice
-
Brusa, R., Zimmermann, F., Koh, D. S., Feldmeyer, D., Gass, P., Seeburg, P. H., and Sprengel, R., Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice, Science, 270(5242) 1677-1680, 1995.
-
(1995)
Science
, vol.270
, Issue.5242
, pp. 1677-1680
-
-
Brusa, R.1
Zimmermann, F.2
Koh, D.S.3
Feldmeyer, D.4
Gass, P.5
Seeburg, P.H.6
Sprengel, R.7
-
168
-
-
0027997686
-
Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1
-
Conquet, F., Bashir, Z. I., Davies, C. H., Daniel, H., Ferraguti, F., Bordi, F., Franz-Bacon, K., Reggiani, A., Matarese, V., Conde, F., Collingridge, G. L., and Crepel, F., Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1, Nature, 372(6503), 237-243, 1994.
-
(1994)
Nature
, vol.372
, Issue.6503
, pp. 237-243
-
-
Conquet, F.1
Bashir, Z.I.2
Davies, C.H.3
Daniel, H.4
Ferraguti, F.5
Bordi, F.6
Franz-Bacon, K.7
Reggiani, A.8
Matarese, V.9
Conde, F.10
Collingridge, G.L.11
Crepel, F.12
-
169
-
-
0028149789
-
Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice
-
Aiba, A., Kano, M., Chen, C., Stanton, M. E., Fox, G. D., Herrup, K., Zwingman, T. A., and Tonegawa, S., Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice, Cell, 79(2) 377-388 1994.
-
(1994)
Cell
, vol.79
, Issue.2
, pp. 377-388
-
-
Aiba, A.1
Kano, M.2
Chen, C.3
Stanton, M.E.4
Fox, G.D.5
Herrup, K.6
Zwingman, T.A.7
Tonegawa, S.8
-
170
-
-
0029591742
-
Impaired synapse elimination during cerebellar development in PKC gamma mutant mice
-
Kano, M., Hashimoto, K., Chen, C., Abeliovich, A., Aiba, A., Kurihara, H., Watanabe, M., Inoue, Y., and Tonegawa, S., Impaired synapse elimination during cerebellar development in PKC gamma mutant mice, Cell, 83(7), 1223-1231, 1995.
-
(1995)
Cell
, vol.83
, Issue.7
, pp. 1223-1231
-
-
Kano, M.1
Hashimoto, K.2
Chen, C.3
Abeliovich, A.4
Aiba, A.5
Kurihara, H.6
Watanabe, M.7
Inoue, Y.8
Tonegawa, S.9
-
171
-
-
0031465157
-
Conditioned eyeblink response is impaired in mutant mice lacking NMDA receptor subunit NR2A
-
Kishimoto, Y., Kawahara, S., Kirino, Y., Kadotani, H., Nakamura, Y., Ikeda, M., and Yoshioka, T., Conditioned eyeblink response is impaired in mutant mice lacking NMDA receptor subunit NR2A, Neuroreport, 8(17), 3717-3721, 1997.
-
(1997)
Neuroreport
, vol.8
, Issue.17
, pp. 3717-3721
-
-
Kishimoto, Y.1
Kawahara, S.2
Kirino, Y.3
Kadotani, H.4
Nakamura, Y.5
Ikeda, M.6
Yoshioka, T.7
-
172
-
-
0029023325
-
Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice
-
Kashiwabuchi, N., Ikeda, K., Araki, K., Hirano, T., Shibuki, K., Takayama, C., Inoue, Y., Kutsuwada, T., Yagi, T., Kang, Y., Aizawa, S., and Mishina, M., Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice, Cell, 81(2), 245-252, 1995.
-
(1995)
Cell
, vol.81
, Issue.2
, pp. 245-252
-
-
Kashiwabuchi, N.1
Ikeda, K.2
Araki, K.3
Hirano, T.4
Shibuki, K.5
Takayama, C.6
Inoue, Y.7
Kutsuwada, T.8
Yagi, T.9
Kang, Y.10
Aizawa, S.11
Mishina, M.12
-
173
-
-
0029814483
-
Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor
-
Pekhletski, R., Gerlai, R., Overstreet, L.S., Huang, X.P., Agopyan, N., Slater, N.T., Abramow-Newerly, W., Roder, J. C., and Hampson, D. R., Impaired cerebellar synaptic plasticity and motor performance in mice lacking the mGluR4 subtype of metabotropic glutamate receptor, J. Neurosci., 16(20), 6364-6373, 1996.
-
(1996)
J. Neurosci.
, vol.16
, Issue.20
, pp. 6364-6373
-
-
Pekhletski, R.1
Gerlai, R.2
Overstreet, L.S.3
Huang, X.P.4
Agopyan, N.5
Slater, N.T.6
Abramow-Newerly, W.7
Roder, J.C.8
Hampson, D.R.9
-
174
-
-
0032499277
-
Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in Glur6-deficient mice
-
Mulle, C., Sailer, A., Perez-Otano, I., Dickinson-Anson, H., Castillo, P. E., Bureau, I., Maron, C., Gage, F. H., Mann, J. R., Bettler, B., and Heinemann, S. F., Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in Glur6-deficient mice, Nature, 392(6676), 601-605, 1998.
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 601-605
-
-
Mulle, C.1
Sailer, A.2
Perez-Otano, I.3
Dickinson-Anson, H.4
Castillo, P.E.5
Bureau, I.6
Maron, C.7
Gage, F.H.8
Mann, J.R.9
Bettler, B.10
Heinemann, S.F.11
-
175
-
-
0030600546
-
Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures
-
Asada, H., Kawamura, Y., Maruyama, K., Kume, H., Ding, R., Ji, F.Y., Kanbara, N., Kuzume, H., Sanbo, M., Yagi, T., and Obata, K., Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures, Biochem. Biophys. Res. Commun., 229(3), 891-895 1996.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.229
, Issue.3
, pp. 891-895
-
-
Asada, H.1
Kawamura, Y.2
Maruyama, K.3
Kume, H.4
Ding, R.5
Ji, F.Y.6
Kanbara, N.7
Kuzume, H.8
Sanbo, M.9
Yagi, T.10
Obata, K.11
-
176
-
-
12644290240
-
Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy cleft palate, and hypersensitive behavior
-
Romanics, G. E., DeLorey, T. M., Firestone, L. L., Quinlan, J. J., Handforth, A., Harrison, N. L., Krasowski, M. D., Rick, C. E., Korpi, E. R., Makela, R., Brilliant, M. H., Hagiwara, N., Ferguson, C., Snyder, K., and Olsen, R. W., Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy cleft palate, and hypersensitive behavior, Proc. Natl. Acad. Sci. U.S.A., 94(B) 4143-4148, 1997
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.B
, pp. 4143-4148
-
-
Romanics, G.E.1
DeLorey, T.M.2
Firestone, L.L.3
Quinlan, J.J.4
Handforth, A.5
Harrison, N.L.6
Krasowski, M.D.7
Rick, C.E.8
Korpi, E.R.9
Makela, R.10
Brilliant, M.H.11
Hagiwara, N.12
Ferguson, C.13
Snyder, K.14
Olsen, R.W.15
-
177
-
-
0028786947
-
Deficiency of the beta 3 subunit of the type A gamma-aminobutyric acid receptor causes cleft palate in mice
-
Culiat, C. T., Stubbs, L. J., Woychik, R. P., Russell, L. B., Johnson, D. K., and Rinchik, E. M., Deficiency of the beta 3 subunit of the type A gamma-aminobutyric acid receptor causes cleft palate in mice, Nat. Genet., 11(3), 344-346, 1995.
-
(1995)
Nat. Genet.
, vol.11
, Issue.3
, pp. 344-346
-
-
Culiat, C.T.1
Stubbs, L.J.2
Woychik, R.P.3
Russell, L.B.4
Johnson, D.K.5
Rinchik, E.M.6
-
178
-
-
0030615289
-
Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: Lack of effect on responses to ethanol, pentobarbital, and general anesthetics
-
Romanics, G. E., Ferguson, C., Quinlan, J. J., Daggett, J., Snyder, K., Lagenaur, C., Mi, Z. P., Wang, X. H., Grayson, D. R., and Firestone, L. L., Gene knockout of the alpha6 subunit of the gamma-aminobutyric acid type A receptor: lack of effect on responses to ethanol, pentobarbital, and general anesthetics, Mol. Pharmacol., 51(4), 588-596, 1997.
-
(1997)
Mol. Pharmacol.
, vol.51
, Issue.4
, pp. 588-596
-
-
Romanics, G.E.1
Ferguson, C.2
Quinlan, J.J.3
Daggett, J.4
Snyder, K.5
Lagenaur, C.6
Mi, Z.P.7
Wang, X.H.8
Grayson, D.R.9
Firestone, L.L.10
-
179
-
-
0030931721
-
VMAT2 knockout mice: Heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity
-
Takahashi, N., Miner, L. L., Sora, I., Ujike, H., Revay, R. S., Kostic, V., Jackson-Lewis, V., Przedborski, S., and Uhl, G. R., VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity, Proc. Natl. Acad. Sci. U.S.A., 94(18), 9938-9943, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.18
, pp. 9938-9943
-
-
Takahashi, N.1
Miner, L.L.2
Sora, I.3
Ujike, H.4
Revay, R.S.5
Kostic, V.6
Jackson-Lewis, V.7
Przedborski, S.8
Uhl, G.R.9
-
180
-
-
0031458923
-
Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine
-
Wang, Y. M., Gainetdinov, P. R., Fumagalli, F., Xu, F., Jones, S. R., Bock, C. B., Miller, G. W., Wightman, R. M., and Caron, M. G., Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine, Neuron, 19(6), 1285-1296, 1997.
-
(1997)
Neuron
, vol.19
, Issue.6
, pp. 1285-1296
-
-
Wang, Y.M.1
Gainetdinov, P.R.2
Fumagalli, F.3
Xu, F.4
Jones, S.R.5
Bock, C.B.6
Miller, G.W.7
Wightman, R.M.8
Caron, M.G.9
-
181
-
-
0029877297
-
A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice
-
Accili, D., Fishburn, C. S., Drago, J., Steiner, H., Lachowicz, J. E., Park, B. H., Gauda, E. B., Lee, E. J., Cool, M. H., Sibley, D. R., Gerfen, C. R., Westphal, H., and Fuchs, S., A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice, Proc. Natl. Acad. Sci. U.S.A., 93(5), 1945-1949, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.5
, pp. 1945-1949
-
-
Accili, D.1
Fishburn, C.S.2
Drago, J.3
Steiner, H.4
Lachowicz, J.E.5
Park, B.H.6
Gauda, E.B.7
Lee, E.J.8
Cool, M.H.9
Sibley, D.R.10
Gerfen, C.R.11
Westphal, H.12
Fuchs, S.13
-
182
-
-
0032520839
-
Alterations in dopamine release but not dopamine autoreceptor function in dopamine D-3 receptor mutant mice
-
Koeltzow, T. E., Xu, M., Cooper, D. C., Hu, X. T., Tonegawa, S., Wolf, M. E., and White, F. J., Alterations in dopamine release but not dopamine autoreceptor function in dopamine D-3 receptor mutant mice, J. Neurosci., 18(6), 2231-2238, 1998.
-
(1998)
J. Neurosci.
, vol.18
, Issue.6
, pp. 2231-2238
-
-
Koeltzow, T.E.1
Xu, M.2
Cooper, D.C.3
Hu, X.T.4
Tonegawa, S.5
Wolf, M.E.6
White, F.J.7
-
183
-
-
0029165456
-
Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors
-
Baik, J. H., Picetti, R., Saiardi, A., Thiriet, G., Dierich, A., Depaulis, A., Le Meur, M., and Borrelli, E., Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors, Nature, 377(6548), 424-428, 1995.
-
(1995)
Nature
, vol.377
, Issue.6548
, pp. 424-428
-
-
Baik, J.H.1
Picetti, R.2
Saiardi, A.3
Thiriet, G.4
Dierich, A.5
Depaulis, A.6
Le Meur, M.7
Borrelli, E.8
-
184
-
-
20244389989
-
Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage genetic background, and developmental adaptations
-
Kelly, M. A., Rubinstein, M., Phillips, T. J., Lessov, C. N., Burkhartkasch, S., Zhang, G., Bunzow, J. R., Fang, Y., Gerhardt, G. A., Grandy, D. K., and Low, M. J., Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage genetic background, and developmental adaptations, J. Neurosci., 18(9) 3470-3479, 1998.
-
(1998)
J. Neurosci.
, vol.18
, Issue.9
, pp. 3470-3479
-
-
Kelly, M.A.1
Rubinstein, M.2
Phillips, T.J.3
Lessov, C.N.4
Burkhartkasch, S.5
Zhang, G.6
Bunzow, J.R.7
Fang, Y.8
Gerhardt, G.A.9
Grandy, D.K.10
Low, M.J.11
-
185
-
-
0030955365
-
Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetarnine
-
Rubinstein, M., Phillips, T. J., Bunzow, J. R., Falzone, T. L., Dziewczapolski, G., Zhang, G., Fang, Y., Larson, J. L., McDougall, J. A., Chester, J. A., Saez, C., Pugsley, T. A., Gershanik, O., Low, M. J., and Grandy, D. K., Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetarnine, Cell, 90(6), 991-1001, 1997.
-
(1997)
Cell
, vol.90
, Issue.6
, pp. 991-1001
-
-
Rubinstein, M.1
Phillips, T.J.2
Bunzow, J.R.3
Falzone, T.L.4
Dziewczapolski, G.5
Zhang, G.6
Fang, Y.7
Larson, J.L.8
McDougall, J.A.9
Chester, J.A.10
Saez, C.11
Pugsley, T.A.12
Gershanik, O.13
Low, M.J.14
Grandy, D.K.15
-
186
-
-
0032488783
-
Impaired locomotion and dopamine signaling in retinoid receptor mutant mice
-
Krezel, W., Ghyselinck, N., Samad, T. A., Dupe, V., Kastner, P., Borrelli, E., and Chambon, P., Impaired locomotion and dopamine signaling in retinoid receptor mutant mice, Science, 279(5352), 863-867 1998.
-
(1998)
Science
, vol.279
, Issue.5352
, pp. 863-867
-
-
Krezel, W.1
Ghyselinck, N.2
Samad, T.A.3
Dupe, V.4
Kastner, P.5
Borrelli, E.6
Chambon, P.7
-
187
-
-
0030071106
-
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
-
Giros, B., Jaber, M., Jones, S. R., Wightman, R. M., and Caron, M. G., Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter, Nature, 379(6566), 606-612, 1996.
-
(1996)
Nature
, vol.379
, Issue.6566
, pp. 606-612
-
-
Giros, B.1
Jaber, M.2
Jones, S.R.3
Wightman, R.M.4
Caron, M.G.5
-
188
-
-
0029066498
-
Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA
-
Cases, O., Seif, I., Grimsby, J., Caspar, P., Chen, K., Pournin, S., Muller, U., Aguet, M., Babinet, C., Shih, J. C., and De Maeyer, E., Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA, Science, 268(5218), 1763-1766, 1995.
-
(1995)
Science
, vol.268
, Issue.5218
, pp. 1763-1766
-
-
Cases, O.1
Seif, I.2
Grimsby, J.3
Caspar, P.4
Chen, K.5
Pournin, S.6
Muller, U.7
Aguet, M.8
Babinet, C.9
Shih, J.C.10
De Maeyer, E.11
-
189
-
-
0030058732
-
Lack of barrels in the somatosensory cortex of monoamine oxidase A-deficient mice: Role of a serotonin excess during the critical period
-
Cases, O., Vitalis, T., Seif, I., De Maeyer, E., Sotelo, C., and Gaspar, P., Lack of barrels in the somatosensory cortex of monoamine oxidase A-deficient mice: role of a serotonin excess during the critical period, Neuron, 16(2), 297-307, 1996.
-
(1996)
Neuron
, vol.16
, Issue.2
, pp. 297-307
-
-
Cases, O.1
Vitalis, T.2
Seif, I.3
De Maeyer, E.4
Sotelo, C.5
Gaspar, P.6
-
190
-
-
12644279880
-
Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice
-
Kim, J. J., Shih, J. C., Chen, K., Chen, L., Bao, S., Maren, S., Anagnostaras, S. G., Fanselow, M. S., De Maeyer, E., Seif, I., and Thompson, R. F., Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice, Proc. Natl. Acad. Sci. U.S.A., 94(11) 5929-5933, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.11
, pp. 5929-5933
-
-
Kim, J.J.1
Shih, J.C.2
Chen, K.3
Chen, L.4
Bao, S.5
Maren, S.6
Anagnostaras, S.G.7
Fanselow, M.S.8
De Maeyer, E.9
Seif, I.10
Thompson, R.F.11
-
191
-
-
0028909857
-
Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors
-
Tecott, L. H., Sun, L. M., Akana, S. F., Strack, A. M., Lowenstein, D. H., Dallman, M. F., and Julius, D., Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors, Nature, 374(6522), 542-546, 1995.
-
(1995)
Nature
, vol.374
, Issue.6522
, pp. 542-546
-
-
Tecott, L.H.1
Sun, L.M.2
Akana, S.F.3
Strack, A.M.4
Lowenstein, D.H.5
Dallman, M.F.6
Julius, D.7
-
192
-
-
0028132273
-
Enhanced aggressive behavior in mice lacking 5-HT1B receptor
-
Saudou, F., Amara, D. A., Dierich, A., LeMeur, M., Ramboz, S., Segu, L., Buhot, M. C., and Hen, R., Enhanced aggressive behavior in mice lacking 5-HT1B receptor, Science, 265(5180), 1875-1878, 1994.
-
(1994)
Science
, vol.265
, Issue.5180
, pp. 1875-1878
-
-
Saudou, F.1
Amara, D.A.2
Dierich, A.3
LeMeur, M.4
Ramboz, S.5
Segu, L.6
Buhot, M.C.7
Hen, R.8
-
193
-
-
0029416835
-
Regulation of [3H]5-HT release in raphe, frontal cortex, and hippocampus of 5-HT1B knock-out mice
-
Pineyro, G., Castanon, N., Hen, R., and Blier, P., Regulation of [3H]5-HT release in raphe, frontal cortex, and hippocampus of 5-HT1B knock-out mice, Neuroreport, 7(1), 353-359, 1995.
-
(1995)
Neuroreport
, vol.7
, Issue.1
, pp. 353-359
-
-
Pineyro, G.1
Castanon, N.2
Hen, R.3
Blier, P.4
-
194
-
-
0030612227
-
1B knock-out mice
-
1B knock-out mice, Psychopharmacology, 132, 125-134, 1997.
-
(1997)
Psychopharmacology
, vol.132
, pp. 125-134
-
-
Dulawa, S.C.1
Hen, R.2
Scearce-Levie, K.3
Geyer, M.4
-
195
-
-
0028935117
-
Noradrenaline is essential for mouse fetal development
-
Thomas, S. A., Matsumoto, A. M., and Palmiter, R. D., Noradrenaline is essential for mouse fetal development, Nature, 374(6523), 643-646, 1995.
-
(1995)
Nature
, vol.374
, Issue.6523
, pp. 643-646
-
-
Thomas, S.A.1
Matsumoto, A.M.2
Palmiter, R.D.3
-
196
-
-
0030782406
-
Impaired maternal behavior in mice lacking norepinephrine and epinephrine
-
Thomas, S. A. and Palmiter, R. D., Impaired maternal behavior in mice lacking norepinephrine and epinephrine, Cell, 91(5), 583-592, 1997.
-
(1997)
Cell
, vol.91
, Issue.5
, pp. 583-592
-
-
Thomas, S.A.1
Palmiter, R.D.2
-
197
-
-
0030015497
-
Targeted disruption of the mouse beta 1-adrenergic receptor gene: Developmental and cardiovascular effects
-
Rohrer, D. K., Desai, K. H., Jasper, J. R., Stevens, M. E., Regula, D. P., Jr., Barsh, G. S., Bernstein, D., and Kobilka, B. K., Targeted disruption of the mouse beta 1-adrenergic receptor gene: developmental and cardiovascular effects, Proc. Natl. Acad. Sci. U.S.A., 93(14), 7375-7380, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.14
, pp. 7375-7380
-
-
Rohrer, D.K.1
Desai, K.H.2
Jasper, J.R.3
Stevens, M.E.4
Regula Jr., D.P.5
Barsh, G.S.6
Bernstein, D.7
Kobilka, B.K.8
-
198
-
-
0028838836
-
Targeted disruption of the beta 3-adrenergic receptor gene
-
Susulic, V. S., Frederich, R. C., Lawitts, J., Tozzo, E., Kahn, B. B., Harper, M. E., Himms-Hagen, J., Flier, J. S., and Lowell, B. B., Targeted disruption of the beta 3-adrenergic receptor gene, J. Biol. Chem., 270(49), 29483-29492, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.49
, pp. 29483-29492
-
-
Susulic, V.S.1
Frederich, R.C.2
Lawitts, J.3
Tozzo, E.4
Kahn, B.B.5
Harper, M.E.6
Himms-Hagen, J.7
Flier, J.S.8
Lowell, B.B.9
-
199
-
-
0029739504
-
Cardiovascular regulation in mice lacking alpha 2-adrenergic receptor subtypes b and c
-
Link, R. E., Desai, K., Hein, L., Stevens, M. E., Chruscinski, A., Bernstein, D., Barsh, G. S., and Kobilka, B. K., Cardiovascular regulation in mice lacking alpha 2-adrenergic receptor subtypes b and c, Science, 273(5276), 803-805, 1996.
-
(1996)
Science
, vol.273
, Issue.5276
, pp. 803-805
-
-
Link, R.E.1
Desai, K.2
Hein, L.3
Stevens, M.E.4
Chruscinski, A.5
Bernstein, D.6
Barsh, G.S.7
Kobilka, B.K.8
-
200
-
-
0029777474
-
Central hypotensive effects of the alpha 2a-adrenergic receptor subtype
-
MacMillan, L. B., Hein, L., Smith, M. S., Piascik, M. T., and Limbird, L. E., Central hypotensive effects of the alpha 2a-adrenergic receptor subtype, Science, 273(5276), 801-803, 1996.
-
(1996)
Science
, vol.273
, Issue.5276
, pp. 801-803
-
-
MacMillan, L.B.1
Hein, L.2
Smith, M.S.3
Piascik, M.T.4
Limbird, L.E.5
-
201
-
-
0032520845
-
A point mutation (d79n) of the alpha-2a adrenergic receptor abolishes the antiepileptogenic action of endogenous norepinephrine
-
Janumpalli, S., Butler, L. S., Macmillan, L. B., Limbird, L. E., and McNamara, J. O., A point mutation (d79n) of the alpha-2a adrenergic receptor abolishes the antiepileptogenic action of endogenous norepinephrine, J. Neurosci, 18(6), 2004-2008, 1998.
-
(1998)
J. Neurosci
, vol.18
, Issue.6
, pp. 2004-2008
-
-
Janumpalli, S.1
Butler, L.S.2
Macmillan, L.B.3
Limbird, L.E.4
McNamara, J.O.5
-
202
-
-
0032521675
-
Adrenergic alpha(2c)-receptors modulate the acoustic startle reflex, prepulse inhibition, and aggression in mice
-
Sallinen, J., Haapalinna, A., Viitamaa, T., Kobilka, B. K., and Scheinin, M., Adrenergic alpha(2c)-receptors modulate the acoustic startle reflex, prepulse inhibition, and aggression in mice, J. Neurosci., 18(8), 3035-3042, 1998.
-
(1998)
J. Neurosci.
, vol.18
, Issue.8
, pp. 3035-3042
-
-
Sallinen, J.1
Haapalinna, A.2
Viitamaa, T.3
Kobilka, B.K.4
Scheinin, M.5
-
203
-
-
0027524610
-
Brief presentation of the story and present status of studies of the vertebrate cholinergic system
-
Karczmar, A. G., Brief presentation of the story and present status of studies of the vertebrate cholinergic system, Neuropsychopharmacology, 9(3), 181-199, 1993.
-
(1993)
Neuropsychopharmacology
, vol.9
, Issue.3
, pp. 181-199
-
-
Karczmar, A.G.1
-
204
-
-
0025884565
-
Functional architecture of the nicotinic acetylcholine receptor: From electric organ to brain
-
Galzi, J.-L., Revah, F., Bessis, A., and Changeux, J.-P., Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain, Annu. Rev. Pharmacol., 31, 37-72, 1991.
-
(1991)
Annu. Rev. Pharmacol.
, vol.31
, pp. 37-72
-
-
Galzi, J.-L.1
Revah, F.2
Bessis, A.3
Changeux, J.-P.4
-
205
-
-
0029661887
-
Acetylcholine receptor epsilon-subunit deletion causes muscle weakness and atrophy in juvenile and adult mice
-
Witzemann, V., Schwarz, H., Koenen, M., Berberich, C., Villarroel, A., Wernig, A., Brenner, H. R., and Sakmann, B., Acetylcholine receptor epsilon-subunit deletion causes muscle weakness and atrophy in juvenile and adult mice, Proc. Natl. Acad. Sci. U.S.A., 93(23), 13286-13291, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.23
, pp. 13286-13291
-
-
Witzemann, V.1
Schwarz, H.2
Koenen, M.3
Berberich, C.4
Villarroel, A.5
Wernig, A.6
Brenner, H.R.7
Sakmann, B.8
-
206
-
-
0030708762
-
Disruption of the M1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice
-
Hamilton, S. E., Loose, M. D., Qi, M., Levey, A. I., Hille, B., McKnight, G. S., Idzerda, R. L., and Nathanson, N. M., Disruption of the M1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice, Proc. Natl. Acad. Sci U.S.A., 94(24), 13311-13316, 1997.
-
(1997)
Proc. Natl. Acad. Sci U.S.A.
, vol.94
, Issue.24
, pp. 13311-13316
-
-
Hamilton, S.E.1
Loose, M.D.2
Qi, M.3
Levey, A.I.4
Hille, B.5
McKnight, G.S.6
Idzerda, R.L.7
Nathanson, N.M.8
-
207
-
-
0030613669
-
Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents
-
Orr-Utreger, A., Goldner, F. M., Saeki, M., Lorenzo, I., Golberg, L., De Biasi, M., Dani, J. A., Patrick, J. W., and Beaudet, A. L., Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents, J. Neurosci., 17(23), 9165-9171, 1997.
-
(1997)
J. Neurosci.
, vol.17
, Issue.23
, pp. 9165-9171
-
-
Orr-Utreger, A.1
Goldner, F.M.2
Saeki, M.3
Lorenzo, I.4
Golberg, L.5
De Biasi, M.6
Dani, J.A.7
Patrick, J.W.8
Beaudet, A.L.9
-
208
-
-
17144413330
-
Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain
-
Picciotto, M. R., Zoli, M., Lena, C., Bessis, A., Lallemand, Y., LeNovere, N., Vincent, P., Pich, E. M., Brulet, P., and Changeux, J. P., Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain, Nature, 374(6517), 65-67, 1995.
-
(1995)
Nature
, vol.374
, Issue.6517
, pp. 65-67
-
-
Picciotto, M.R.1
Zoli, M.2
Lena, C.3
Bessis, A.4
Lallemand, Y.5
LeNovere, N.6
Vincent, P.7
Pich, E.M.8
Brulet, P.9
Changeux, J.P.10
-
209
-
-
0008711670
-
Gene targeting of the alpha7 and beta2 subunits and the beta4, alpha3, and alpha5 cluster of neuronal nicotinic acetylcholine receptors
-
Xu, W., Sutcliffe, C. B., Lorenzo, I., Goldberg, L., Dang, H., Patrick, J., Beaudet, A. L., and Orr-Utreger, A., Gene targeting of the alpha7 and beta2 subunits and the beta4, alpha3, and alpha5 cluster of neuronal nicotinic acetylcholine receptors, Soc. Neurosci. Abstr., 23, 391, 1997.
-
(1997)
Soc. Neurosci. Abstr.
, vol.23
, pp. 391
-
-
Xu, W.1
Sutcliffe, C.B.2
Lorenzo, I.3
Goldberg, L.4
Dang, H.5
Patrick, J.6
Beaudet, A.L.7
Orr-Utreger, A.8
-
210
-
-
0032495515
-
Acetylcholine receptors containing the β2-subunit are involved in the reinforcing properties of nicotine
-
Picciotto, M. R., Zoli, M., Rimondini, R., Léna, C., Marubio, L. M., Merlo Pich, E., Fuxe, K., and Changeux, J. P., Acetylcholine receptors containing the β2-subunit are involved in the reinforcing properties of nicotine, Nature, 391, 173-177, 1998.
-
(1998)
Nature
, vol.391
, pp. 173-177
-
-
Picciotto, M.R.1
Zoli, M.2
Rimondini, R.3
Léna, C.4
Marubio, L.M.5
Merlo Pich, E.6
Fuxe, K.7
Changeux, J.P.8
-
211
-
-
0029957953
-
Pain responses, anxiety, and aggression in mice deficient in pre-proenkephalin
-
Konig, M., Zimmer, A. M., Steiner, H., Holmes, P. V., Crawley, J. N., Brownstein, M. J., and Zimmer, A., Pain responses, anxiety, and aggression in mice deficient in pre-proenkephalin, Nature, 383(6600), 535-538, 1996.
-
(1996)
Nature
, vol.383
, Issue.6600
, pp. 535-538
-
-
Konig, M.1
Zimmer, A.M.2
Steiner, H.3
Holmes, P.V.4
Crawley, J.N.5
Brownstein, M.J.6
Zimmer, A.7
-
212
-
-
0029880457
-
Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis
-
Rubinstein, M., Mogil, J. S., Japon, M., Chan, E. C., Allen, R. G., and Low, M. J., Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis, Proc. Natl. Acad. Sci. U.S.A., 93(9), 3995-4000, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.9
, pp. 3995-4000
-
-
Rubinstein, M.1
Mogil, J.S.2
Japon, M.3
Chan, E.C.4
Allen, R.G.5
Low, M.J.6
-
213
-
-
0029852678
-
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene
-
Matthes, H. W., Maldonado, R., Simonin, F., Valverde, O., Slowe, S., Kitchen, I., Befort, K., Dierich, A., Le Meur, M., Dolle, P., Tzavara, E., Hanoune, J., Roques, B. P., and Kieffer, B. L., Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene, Nature, 383(6603), 819-823, 1996.
-
(1996)
Nature
, vol.383
, Issue.6603
, pp. 819-823
-
-
Matthes, H.W.1
Maldonado, R.2
Simonin, F.3
Valverde, O.4
Slowe, S.5
Kitchen, I.6
Befort, K.7
Dierich, A.8
Le Meur, M.9
Dolle, P.10
Tzavara, E.11
Hanoune, J.12
Roques, B.P.13
Kieffer, B.L.14
-
214
-
-
0031030042
-
Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia
-
Sora, I., Takahashi, N., Funada, M., Ujike, H., Revay, R. S., Donovan, D. M., Miner, L. L., and Uhl, G. R., Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia, Proc. Natl. Acad. Sci. U.S.A., 94(4), 1544-1549, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.4
, pp. 1544-1549
-
-
Sora, I.1
Takahashi, N.2
Funada, M.3
Ujike, H.4
Revay, R.S.5
Donovan, D.M.6
Miner, L.L.7
Uhl, G.R.8
-
215
-
-
0030756672
-
Opioid-related changes in nociceptive threshold and in tissue levels of enkephalins after target disruption of the gene for neutral endopeptidase (EC 3.4.24.11) in mice
-
Saria, A., Hauser, K. F., Traurig, H. H., Turbek, C. S., Hersh, L., and Gerard, C., Opioid-related changes in nociceptive threshold and in tissue levels of enkephalins after target disruption of the gene for neutral endopeptidase (EC 3.4.24.11) in mice, Neurosci. Lett., 234(1), 27-30, 1997.
-
(1997)
Neurosci. Lett.
, vol.234
, Issue.1
, pp. 27-30
-
-
Saria, A.1
Hauser, K.F.2
Traurig, H.H.3
Turbek, C.S.4
Hersh, L.5
Gerard, C.6
-
216
-
-
0032568417
-
Primary afferent tachykinins are required to experience moderate to intense pain
-
Cao, Y. Q., Mantyh, P. W., Carlson, E. J., Gillespie, A. M., Epstein, C. J., and Basbaum, A. I., Primary afferent tachykinins are required to experience moderate to intense pain, Nature, 392(6674), 390-394, 1998.
-
(1998)
Nature
, vol.392
, Issue.6674
, pp. 390-394
-
-
Cao, Y.Q.1
Mantyh, P.W.2
Carlson, E.J.3
Gillespie, A.M.4
Epstein, C.J.5
Basbaum, A.I.6
-
217
-
-
0032478311
-
Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene
-
Zimmer, A., Zimmer, A. M., Baffi, J., Usdin, T., Reynolds, K., Konig, M., Palkovits, M., and Mezey, E., Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene, Proc. Natl. Acad. Sci. U.S.A., 95(5), 2630-2635, 1998.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, Issue.5
, pp. 2630-2635
-
-
Zimmer, A.1
Zimmer, A.M.2
Baffi, J.3
Usdin, T.4
Reynolds, K.5
Konig, M.6
Palkovits, M.7
Mezey, E.8
-
218
-
-
0032568444
-
Altered nociception, analgesia and aggression in mice lacking the receptor for substance P
-
De Felipe, C., Herrero, J. F., O'Brien, J. A., Palmer, J. A., Doyle, C. A., Smith, A. J., Laird, J. M., Belmonte, C., Cervero, F., and Hunt, S. P., Altered nociception, analgesia and aggression in mice lacking the receptor for substance P, Nature, 392(6674), 394-397, 1998.
-
(1998)
Nature
, vol.392
, Issue.6674
, pp. 394-397
-
-
De Felipe, C.1
Herrero, J.F.2
O'Brien, J.A.3
Palmer, J.A.4
Doyle, C.A.5
Smith, A.J.6
Laird, J.M.7
Belmonte, C.8
Cervero, F.9
Hunt, S.P.10
-
219
-
-
0030906860
-
Peppers and pain. The promise of capsaicin
-
Fusco, B. M. and Giacovazzo, M., Peppers and pain. The promise of capsaicin., Drugs, 53(6), 909-914, 1997.
-
(1997)
Drugs
, vol.53
, Issue.6
, pp. 909-914
-
-
Fusco, B.M.1
Giacovazzo, M.2
-
220
-
-
0031137336
-
Mechanisms of actions of opioids and nonsteroidal anti-inflammatory drugs
-
Bovill, J. G., Mechanisms of actions of opioids and nonsteroidal anti-inflammatory drugs, Eur. J. Anaesthesiol. Suppl., 15, 9-15, 1997.
-
(1997)
Eur. J. Anaesthesiol. Suppl.
, vol.15
, pp. 9-15
-
-
Bovill, J.G.1
-
221
-
-
0020803854
-
Ca2+ in the control of active intestinal Na and Cl transport: Involvement in neurohumoral action
-
Donowitz, M., Ca2+ in the control of active intestinal Na and Cl transport: involvement in neurohumoral action, Am. J. Physiol., 245(2), G165-G177, 1983.
-
(1983)
Am. J. Physiol.
, vol.245
, Issue.2
-
-
Donowitz, M.1
-
222
-
-
0030881680
-
Preserved acute pain and reduced neuropathic pain in mice lacking PKCgamma
-
Malmberg, A. B., Chen, C., Tonegawa, S., and Basbaum, A. I., Preserved acute pain and reduced neuropathic pain in mice lacking PKCgamma, Science, 278(5336), 279-283, 1997.
-
(1997)
Science
, vol.278
, Issue.5336
, pp. 279-283
-
-
Malmberg, A.B.1
Chen, C.2
Tonegawa, S.3
Basbaum, A.I.4
-
223
-
-
0030841539
-
Diminished inflammation and nociceptive pain with preservation of neuropathic pain in mice with a targeted mutation of the type I regulatory subunit of cAMP-dependent protein kinase
-
Malmberg, A. B., Brandon, E. P., Idzerda, R. L., Liu, H., McKnight, G. S. and Basbaum, A. I., Diminished inflammation and nociceptive pain with preservation of neuropathic pain in mice with a targeted mutation of the type I regulatory subunit of cAMP-dependent protein kinase, J. Neurosci., 17(19), 7462-7470, 1997.
-
(1997)
J. Neurosci.
, vol.17
, Issue.19
, pp. 7462-7470
-
-
Malmberg, A.B.1
Brandon, E.P.2
Idzerda, R.L.3
Liu, H.4
McKnight, G.S.5
Basbaum, A.I.6
-
224
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., and Friedman, J. M., Positional cloning of the mouse obese gene and its human homologue, Nature, 372(6505), 425-432 1994.
-
(1994)
Nature
, vol.372
, Issue.6505
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
225
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia, L. A., Dembski, M., Weng, X., Deng, N., Culpepper, J., Devos, R., Richards, G. J., Campfield, L. A., Clark, F. T., Deeds, J., Muir, C., Sanker, D, Moriarty, A., Woolf, E. A., and Monroe, C. A., Identification and expression cloning of a leptin receptor, OB-R, Cell, 83(7) 1263-1271 1995.
-
(1995)
Cell
, vol.83
, Issue.7
, pp. 1263-1271
-
-
Tartaglia, L.A.1
Dembski, M.2
Weng, X.3
Deng, N.4
Culpepper, J.5
Devos, R.6
Richards, G.J.7
Campfield, L.A.8
Clark, F.T.9
Deeds, J.10
Muir, C.11
Sanker, D.12
Moriarty, A.13
Woolf, E.A.14
Monroe, C.A.15
-
226
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/ db mice
-
Chen, H., Charlat, O., Tartaglia, L. A., Woolf, E. A., Weng, X., Ellis, S. J., Lakey, N. D., Culpepper, J., Moore, K. J., Breitbart, R. E., Duyk, G. M., Tepper, R. I., and Morgenstern, J. P., Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/ db mice, Cell, 84(3), 491-495, 1996.
-
(1996)
Cell
, vol.84
, Issue.3
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
Moore, K.J.9
Breitbart, R.E.10
Duyk, G.M.11
Tepper, R.I.12
Morgenstern, J.P.13
-
227
-
-
0029946644
-
Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
-
Erickson, J. C., Clegg, K. E., and Palmiter, R. D., Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y,Nature, 381(6581), 415-421, 1996.
-
(1996)
Nature
, vol.381
, Issue.6581
, pp. 415-421
-
-
Erickson, J.C.1
Clegg, K.E.2
Palmiter, R.D.3
-
228
-
-
0029804743
-
Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y
-
Erickson, J. C., Hollopeter, G., and Palmiter, R. D., Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y, Science, 274(5293), 1704-1707, 1996.
-
(1996)
Science
, vol.274
, Issue.5293
, pp. 1704-1707
-
-
Erickson, J.C.1
Hollopeter, G.2
Palmiter, R.D.3
-
229
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar, D., Lynch, C. A., Fairchild-Huntress, V., Dunmore, J. H., Fang, Q., Berkemeier, L. R., Gu, W., Kesterson, R. A., Boston, B. A., Cone, R. D., Smith, F. J., Campfield, L. A., Burn, P., and Lee, F., Targeted disruption of the melanocortin-4 receptor results in obesity in mice, Cell, 88, 131-141, 1997.
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
Smith, F.J.11
Campfield, L.A.12
Burn, P.13
Lee, F.14
-
230
-
-
0030764741
-
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
-
Ollmann, M. M., Wilson, B. D., Yang, Y. K., Kerns, J. A., Chen, Y., Gantz, I., and Barsh, G. S., Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein, Science, 278(5335), 135-138, 1997.
-
(1997)
Science
, vol.278
, Issue.5335
, pp. 135-138
-
-
Ollmann, M.M.1
Wilson, B.D.2
Yang, Y.K.3
Kerns, J.A.4
Chen, Y.5
Gantz, I.6
Barsh, G.S.7
-
231
-
-
13144279323
-
Loss of bombesin-induced feeding suppression in gastrin-releasing peptide receptor-deficient mice
-
Hampton, L. L., Ladenheim, E. E., Akeson, M., Way, J. M., Weber, H. C., Sutliff, V. E., Jensen, R. T., Wine, L. J., Arnheiter, H., and Battey, J. F., Loss of bombesin-induced feeding suppression in gastrin-releasing peptide receptor-deficient mice, Proc. Natl. Acad. Sci. U.S.A., 95(6), 3188-3192, 1998.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, Issue.6
, pp. 3188-3192
-
-
Hampton, L.L.1
Ladenheim, E.E.2
Akeson, M.3
Way, J.M.4
Weber, H.C.5
Sutliff, V.E.6
Jensen, R.T.7
Wine, L.J.8
Arnheiter, H.9
Battey, J.F.10
-
232
-
-
0028936097
-
Transgenic approaches to cognition
-
Mayford, M., Abel, T., and Kandel, E. R., Transgenic approaches to cognition, Curr. Opin. Neurobiol, 5(2), 141-148, 1995.
-
(1995)
Curr. Opin. Neurobiol
, vol.5
, Issue.2
, pp. 141-148
-
-
Mayford, M.1
Abel, T.2
Kandel, E.R.3
-
233
-
-
0024455878
-
Synaptic plasticity and learning: Selective impairment of learning in rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5
-
Morris, R. G. M., Synaptic plasticity and learning: selective impairment of learning in rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5, J. Neurosci., 9(9), 3040-3057, 1989.
-
(1989)
J. Neurosci.
, vol.9
, Issue.9
, pp. 3040-3057
-
-
Morris, R.G.M.1
-
234
-
-
0018344553
-
Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat
-
Barnes, C. A., Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat, J. Comp. Physiol. Psychol., 93(1), 74-104, 1979.
-
(1979)
J. Comp. Physiol. Psychol.
, vol.93
, Issue.1
, pp. 74-104
-
-
Barnes, C.A.1
-
235
-
-
0031027229
-
Hippocampal lesions cause learning deficits in inbred mice in the Morris water maze and conditioned-fear task
-
Logue, S. F., Paylor, R., and Wehner, J. M., Hippocampal lesions cause learning deficits in inbred mice in the Morris water maze and conditioned-fear task, Behav. Neurosci., 111(1), 104-113, 1997.
-
(1997)
Behav. Neurosci.
, vol.111
, Issue.1
, pp. 104-113
-
-
Logue, S.F.1
Paylor, R.2
Wehner, J.M.3
-
236
-
-
0027476024
-
A synaptic model of memory: Long-term potentiation in the hippocampus
-
Bliss, T. V. and Collingridge, G. L., A synaptic model of memory: long-term potentiation in the hippocampus, Nature, 361(6407), 31-39, 1993.
-
(1993)
Nature
, vol.361
, Issue.6407
, pp. 31-39
-
-
Bliss, T.V.1
Collingridge, G.L.2
-
237
-
-
0030475008
-
Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice
-
McHugh, T. J., Blum, K. I., Tsien, J. Z., Tonegawa, S., and Wilson, M. A., Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice, Cell, 87, 1339-1349, 1996.
-
(1996)
Cell
, vol.87
, pp. 1339-1349
-
-
McHugh, T.J.1
Blum, K.I.2
Tsien, J.Z.3
Tonegawa, S.4
Wilson, M.A.5
-
238
-
-
0028813106
-
Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit
-
Sakimura, K., Kutsawada, T., Ito, I., Manabe, T., Takayama, C., Kushiya, E., Yagi, T., Aizawa, S., Inoue, Y., Sugiyama, H., and Mishina, M., Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit, Nature, 373(6510), 151-155, 1995.
-
(1995)
Nature
, vol.373
, Issue.6510
, pp. 151-155
-
-
Sakimura, K.1
Kutsawada, T.2
Ito, I.3
Manabe, T.4
Takayama, C.5
Kushiya, E.6
Yagi, T.7
Aizawa, S.8
Inoue, Y.9
Sugiyama, H.10
Mishina, M.11
-
239
-
-
0027941257
-
Synaptic plasticity in the hippocampus: LTP and LTD
-
Malenka, R., Synaptic plasticity in the hippocampus: LTP and LTD, Cell, 78, 535-538, 1994.
-
(1994)
Cell
, vol.78
, pp. 535-538
-
-
Malenka, R.1
-
240
-
-
0028139045
-
Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice
-
Aiba, A., Chen, C., Herrup, K., Rosenmund, C., Stevens, C. F., and Tonegawa, S., Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice, Cell, 79(2), 365-375, 1994.
-
(1994)
Cell
, vol.79
, Issue.2
, pp. 365-375
-
-
Aiba, A.1
Chen, C.2
Herrup, K.3
Rosenmund, C.4
Stevens, C.F.5
Tonegawa, S.6
-
241
-
-
0030004765
-
Reduced long-term potentiation in the dentate gyrus of mGlu1 receptor-mutant mice in vivo
-
Bordi, F., Reduced long-term potentiation in the dentate gyrus of mGlu1 receptor-mutant mice in vivo, Eur. J. Pharmacol., 301(1-3), R15-R16, 1996.
-
(1996)
Eur. J. Pharmacol.
, vol.301
, Issue.1-3
-
-
Bordi, F.1
-
242
-
-
0028829134
-
Evidence against a role for metabotropic glutamate receptors in mossy fiber LTP: The use of mutant mice and pharmacological antagonists
-
Hsia, A. Y., Salin, P. A., Castillo, P. E., Aiba, A., Abeliovich, A., Tonegawa, S., and Nicoll, R. A., Evidence against a role for metabotropic glutamate receptors in mossy fiber LTP: the use of mutant mice and pharmacological antagonists, Neuropharmacology, 34(11), 1567-1572, 1995.
-
(1995)
Neuropharmacology
, vol.34
, Issue.11
, pp. 1567-1572
-
-
Hsia, A.Y.1
Salin, P.A.2
Castillo, P.E.3
Aiba, A.4
Abeliovich, A.5
Tonegawa, S.6
Nicoll, R.A.7
-
243
-
-
9344255435
-
Impairment of hippocarnpal mossy fiber LTD in mice lacking mGluR2
-
Yokoi, M., Kobayashi, K., Manabe, T., Takahashi, T., Sakaguchi, I., Katsuura, G., Shigemoto, R., Ohishi, H., Nomura, S., Nakamura, K., Nakao, K., Katsuki, M., and Nakanishi, S., Impairment of hippocarnpal mossy fiber LTD in mice lacking mGluR2, Science, 273(5275), 645-647, 1996.
-
(1996)
Science
, vol.273
, Issue.5275
, pp. 645-647
-
-
Yokoi, M.1
Kobayashi, K.2
Manabe, T.3
Takahashi, T.4
Sakaguchi, I.5
Katsuura, G.6
Shigemoto, R.7
Ohishi, H.8
Nomura, S.9
Nakamura, K.10
Nakao, K.11
Katsuki, M.12
Nakanishi, S.13
-
244
-
-
0028269289
-
Involvement of postsynaptic G-proteins in hippocampal long-term potentiation
-
Satoh, M. and Kaneko, S., Involvement of postsynaptic G-proteins in hippocampal long-term potentiation, Rev. Neurosci., 5(1), 1-9, 1994.
-
(1994)
Rev. Neurosci.
, vol.5
, Issue.1
, pp. 1-9
-
-
Satoh, M.1
Kaneko, S.2
-
245
-
-
0030294789
-
Enhanced LTP in mice deficient in the AMPA receptor GluR2
-
Jia, Z., Agopyan, N., Miu, P., Xiong, Z., Henderson, J., Gerlai, R., Taverna, F. A., Velumian, A., MacDonald, J., Carlen, P., Abramow-Newerly, W., and Roder, J., Enhanced LTP in mice deficient in the AMPA receptor GluR2, Neuron, 17(5), 945-956, 1996.
-
(1996)
Neuron
, vol.17
, Issue.5
, pp. 945-956
-
-
Jia, Z.1
Agopyan, N.2
Miu, P.3
Xiong, Z.4
Henderson, J.5
Gerlai, R.6
Taverna, F.A.7
Velumian, A.8
MacDonald, J.9
Carlen, P.10
Abramow-Newerly, W.11
Roder, J.12
-
246
-
-
0026637195
-
Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice
-
Silva, A. J., Stevens, C., Tonegawa, S., and Wang, Y., Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice, Science, 257(5067), 201-206, 1992.
-
(1992)
Science
, vol.257
, Issue.5067
, pp. 201-206
-
-
Silva, A.J.1
Stevens, C.2
Tonegawa, S.3
Wang, Y.4
-
247
-
-
0027745596
-
Modified hippocampal long-term potentiation in PKC gamma-mutant mice
-
Abeliovich, A., Chen, C., Goda, Y., Silva, A. J., Stevens, C. F., and Tonegawa, S., Modified hippocampal long-term potentiation in PKC gamma-mutant mice, Cell, 75(7), 1253-1262, 1993.
-
(1993)
Cell
, vol.75
, Issue.7
, pp. 1253-1262
-
-
Abeliovich, A.1
Chen, C.2
Goda, Y.3
Silva, A.J.4
Stevens, C.F.5
Tonegawa, S.6
-
248
-
-
0027787664
-
PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning
-
Abeliovich, A., Paylor, R., Chen, C., Kim, J. J., Wehner, J. M., and Tonegawa, S., PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning, Cell, 75(7), 1263-1271, 1993.
-
(1993)
Cell
, vol.75
, Issue.7
, pp. 1263-1271
-
-
Abeliovich, A.1
Paylor, R.2
Chen, C.3
Kim, J.J.4
Wehner, J.M.5
Tonegawa, S.6
-
249
-
-
13344279399
-
A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning
-
Huang, Y. Y., Kandel, E. R., Varshavsky, L., Brandon, E. P., Qi, M., Idzerda, R. L., McKnight, G. S., and Bourtchouladze, R., A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning, Cell, 83(7), 1211-1222, 1995.
-
(1995)
Cell
, vol.83
, Issue.7
, pp. 1211-1222
-
-
Huang, Y.Y.1
Kandel, E.R.2
Varshavsky, L.3
Brandon, E.P.4
Qi, M.5
Idzerda, R.L.6
McKnight, G.S.7
Bourtchouladze, R.8
-
250
-
-
0029744011
-
Preservation of spatial learning in fyn tyrosine kinase knockout mice
-
Huerta, P. T., Scearce, K. A., Farris, S. M., Empson, R. M., and Prusky, G. T., Preservation of spatial learning in fyn tyrosine kinase knockout mice, Neuroreport, 7(10), 1685-1689, 1996.
-
(1996)
Neuroreport
, vol.7
, Issue.10
, pp. 1685-1689
-
-
Huerta, P.T.1
Scearce, K.A.2
Farris, S.M.3
Empson, R.M.4
Prusky, G.T.5
-
251
-
-
0027976632
-
Initial events of myelination involve Fyn tyrosine kinase signaling
-
Umemori, H., Sato, S., Yagi, T., Aizawa, S., and Yamamoto, T., Initial events of myelination involve Fyn tyrosine kinase signaling, Nature, 367(6463), 572-576, 1994.
-
(1994)
Nature
, vol.367
, Issue.6463
, pp. 572-576
-
-
Umemori, H.1
Sato, S.2
Yagi, T.3
Aizawa, S.4
Yamamoto, T.5
-
252
-
-
0029842659
-
Susceptibility to drug-induced seizures of Fyn tyrosine kinase-deficient mice
-
Miyakawa, T., Yagi, T., Tateishi, K., and Niki, H., Susceptibility to drug-induced seizures of Fyn tyrosine kinase-deficient mice, Neuroreport, 7(15-17), 2723-2726, 1996.
-
(1996)
Neuroreport
, vol.7
, Issue.15-17
, pp. 2723-2726
-
-
Miyakawa, T.1
Yagi, T.2
Tateishi, K.3
Niki, H.4
-
253
-
-
0028895999
-
Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice
-
Miyakawa, T., Yagi, T., Taniguchi, M., Matsuura, H., Tateishi, K., and Niki, H., Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice, Brain Res. Mol. Brain Res., 28(2), 349-352, 1995.
-
(1995)
Brain Res. Mol. Brain Res.
, vol.28
, Issue.2
, pp. 349-352
-
-
Miyakawa, T.1
Yagi, T.2
Taniguchi, M.3
Matsuura, H.4
Tateishi, K.5
Niki, H.6
-
254
-
-
0028113050
-
Increased tearfulness of Fyn tyrosine kinase deficient mice
-
Miyakawa, T., Yagi, T., Watanabe, S., and Niki, H., Increased tearfulness of Fyn tyrosine kinase deficient mice, Brain Res. Mol. Brain Res., 27(1), 179-182, 1994.
-
(1994)
Brain Res. Mol. Brain Res.
, vol.27
, Issue.1
, pp. 179-182
-
-
Miyakawa, T.1
Yagi, T.2
Watanabe, S.3
Niki, H.4
-
255
-
-
0029887733
-
Radial maze performance, open-field and elevated plus-maze behaviors in Fyn-kinase deficient mice: Further evidence for increased fearfulness
-
Miyakawa, T., Yagi, T., Kagiyama, A, and Niki, H., Radial maze performance, open-field and elevated plus-maze behaviors in Fyn-kinase deficient mice: further evidence for increased fearfulness, Brain Res. Mol. Brain Res., 37(1-2), 145-150, 1996.
-
(1996)
Brain Res. Mol. Brain Res.
, vol.37
, Issue.1-2
, pp. 145-150
-
-
Miyakawa, T.1
Yagi, T.2
Kagiyama, A.3
Niki, H.4
-
256
-
-
0027753184
-
A role for Fyn tyrosine kinase in the suckling behavior of neonatal mice
-
Yagi, T., Aizawa, S., Tokunaga, T., Shigetani, Y., Takeda, N., and Ikawa, Y., A role for Fyn tyrosine kinase in the suckling behavior of neonatal mice, Nature, 366(6457), 742-745, 1993.
-
(1993)
Nature
, vol.366
, Issue.6457
, pp. 742-745
-
-
Yagi, T.1
Aizawa, S.2
Tokunaga, T.3
Shigetani, Y.4
Takeda, N.5
Ikawa, Y.6
-
257
-
-
0028108923
-
CREB: A mediator of long-term memory from mollusks to mammals
-
Frank, D. A. and Greenberg, M. E., CREB: a mediator of long-term memory from mollusks to mammals, Cell, 79(1), 5-8, 1994.
-
(1994)
Cell
, vol.79
, Issue.1
, pp. 5-8
-
-
Frank, D.A.1
Greenberg, M.E.2
-
258
-
-
0028899577
-
Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice
-
Wu, Z. L., Thomas, S. A., Villacres, E. C., Xia, Z., Simmons, M. L., Chavkin, C., Palmiter, R. D., and Storm, D. R., Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice, Proc. Natl. Acad. Sci. U.S.A., 92(1), 220-224, 1995.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, Issue.1
, pp. 220-224
-
-
Wu, Z.L.1
Thomas, S.A.2
Villacres, E.C.3
Xia, Z.4
Simmons, M.L.5
Chavkin, C.6
Palmiter, R.D.7
Storm, D.R.8
-
259
-
-
0029915492
-
Hippocampal cell responses in mice with a targeted glucocorticoid receptor gene disruption
-
Hesen, W., Karst, H., Meijer, O., Cole, T. J., Schmid, W., de Kloet, E. R., Schutz, G., and Joels, M., Hippocampal cell responses in mice with a targeted glucocorticoid receptor gene disruption, J. Neurosci, 16(21), 6766-6774, 1996.
-
(1996)
J. Neurosci
, vol.16
, Issue.21
, pp. 6766-6774
-
-
Hesen, W.1
Karst, H.2
Meijer, O.3
Cole, T.J.4
Schmid, W.5
De Kloet, E.R.6
Schutz, G.7
Joels, M.8
-
260
-
-
0029962224
-
Steel mutant mice are deficient in hippocampal learning but not long-term potentiation
-
Motro, B., Wojtowicz, J. M., Bernstein, A., and van der Kooy, D., Steel mutant mice are deficient in hippocampal learning but not long-term potentiation, Proc. Natl. Acad. Sci. U.S.A., 93(5), 1808-1813, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.5
, pp. 1808-1813
-
-
Motro, B.1
Wojtowicz, J.M.2
Bernstein, A.3
Van Der Kooy, D.4
-
261
-
-
13344282736
-
Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1
-
Nosten-Bertrand, M., Errington, M. L., Murphy, K. P., Tokugawa, Y., Barboni, E., Kozlova, E., Michalovich, D., Morris, R. G., Silver, J., Stewart, C. L., Bliss, T. V., and Morris, R. J., Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1, Nature, 379(6568), 826-829, 1996.
-
(1996)
Nature
, vol.379
, Issue.6568
, pp. 826-829
-
-
Nosten-Bertrand, M.1
Errington, M.L.2
Murphy, K.P.3
Tokugawa, Y.4
Barboni, E.5
Kozlova, E.6
Michalovich, D.7
Morris, R.G.8
Silver, J.9
Stewart, C.L.10
Bliss, T.V.11
Morris, R.J.12
-
262
-
-
0030925219
-
Long-term potentiation in awake mutant mice
-
Errington, M. L., Bliss, T. V., Morris, R. J., Laroche, S., and Davis, S., Long-term potentiation in awake mutant mice, Nature, 387(6634), 666-667, 1997.
-
(1997)
Nature
, vol.387
, Issue.6634
, pp. 666-667
-
-
Errington, M.L.1
Bliss, T.V.2
Morris, R.J.3
Laroche, S.4
Davis, S.5
-
263
-
-
0029021177
-
Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor
-
Korte, M., Carroll, P., Wolf, E., Brem, G., Thoenen, H., and Bonhoeffer, T., Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor, Proc. Natl. Acad. Sci. U.S.A., 92(19), 8856-8860, 1995.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, Issue.19
, pp. 8856-8860
-
-
Korte, M.1
Carroll, P.2
Wolf, E.3
Brem, G.4
Thoenen, H.5
Bonhoeffer, T.6
-
264
-
-
0030176079
-
Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice
-
Patterson, S. L., Abel, T., Deuel, T. A., Martin, K. C., Rose, J. C., and Kandel, E. R., Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice, Neuron, 16(6), 1137-1145, 1996.
-
(1996)
Neuron
, vol.16
, Issue.6
, pp. 1137-1145
-
-
Patterson, S.L.1
Abel, T.2
Deuel, T.A.3
Martin, K.C.4
Rose, J.C.5
Kandel, E.R.6
-
265
-
-
0030991457
-
Intact spatial learning and memory in transgenic mice with reduced BDNF
-
Montkowski, A. and Holsboer, F., Intact spatial learning and memory in transgenic mice with reduced BDNF, Neuroreport, 8(3), 779-782, 1997.
-
(1997)
Neuroreport
, vol.8
, Issue.3
, pp. 779-782
-
-
Montkowski, A.1
Holsboer, F.2
-
266
-
-
0030474255
-
Involvement of the amygdala in memory storage: Interaction with other brain systems
-
McGaugh, J. L., Cahill, L., and Roozendaal, B., Involvement of the amygdala in memory storage: interaction with other brain systems, Proc. Natl. Acad. Sci. U.S.A., 93(24), 13508-13514, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.24
, pp. 13508-13514
-
-
McGaugh, J.L.1
Cahill, L.2
Roozendaal, B.3
-
267
-
-
0031581209
-
A role for the ras signaling pathway in synaptic transmission and long-term memory
-
Brambilla, R., Gnesutta, N., Minichiello, L., White, G., Roylance, A. J., Herron, C. E., Ramsey, M., Wolfer, D. P., Cestari, V., Rossiarnaud, C., Grant, S. G. N., Chapman, P. F., Lipp, H. P., Sturani, E., and Klein, R., A role for the ras signaling pathway in synaptic transmission and long-term memory, Nature, 390(6657), 281-286, 1997.
-
(1997)
Nature
, vol.390
, Issue.6657
, pp. 281-286
-
-
Brambilla, R.1
Gnesutta, N.2
Minichiello, L.3
White, G.4
Roylance, A.J.5
Herron, C.E.6
Ramsey, M.7
Wolfer, D.P.8
Cestari, V.9
Rossiarnaud, C.10
Grant, S.G.N.11
Chapman, P.F.12
Lipp, H.P.13
Sturani, E.14
Klein, R.15
-
268
-
-
0026507628
-
Drugs of abuse: Anatomy, pharmacology, and function of reward pathways
-
Koob, G. F., Drugs of abuse: anatomy, pharmacology, and function of reward pathways, Trends Pharmacol. Sci., 13(5), 177-184, 1992.
-
(1992)
Trends Pharmacol. Sci.
, vol.13
, Issue.5
, pp. 177-184
-
-
Koob, G.F.1
-
269
-
-
0030951587
-
Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice
-
Tian, M., Broxmeyer, H. E., Fan, Y., Lai, Z., Zhang, S., Aronica, S., Cooper, S., Bigsby, R. M., Steinmetz, R., Engle, S. J., Mestek, A., Pollock, J. D., Lehman, M. N., Jansen, H. T., Ying, M., Stambrook, P. J., Tischfield, J. A., and Yu, L., Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice, J. Exp. Med., 185(8), 1517-1522, 1997.
-
(1997)
J. Exp. Med.
, vol.185
, Issue.8
, pp. 1517-1522
-
-
Tian, M.1
Broxmeyer, H.E.2
Fan, Y.3
Lai, Z.4
Zhang, S.5
Aronica, S.6
Cooper, S.7
Bigsby, R.M.8
Steinmetz, R.9
Engle, S.J.10
Mestek, A.11
Pollock, J.D.12
Lehman, M.N.13
Jansen, H.T.14
Ying, M.15
Stambrook, P.J.16
Tischfield, J.A.17
Yu, L.18
-
270
-
-
0025760593
-
A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function
-
Terwilliger, R. Z., Beitner-Johnson, D., Sevarino, K. A., Crain, S. M., and Nestler, E. J., A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function, Brain Res., 548(1-2), 100-110, 1991.
-
(1991)
Brain Res.
, vol.548
, Issue.1-2
, pp. 100-110
-
-
Terwilliger, R.Z.1
Beitner-Johnson, D.2
Sevarino, K.A.3
Crain, S.M.4
Nestler, E.J.5
-
271
-
-
0030680941
-
Fyn-kinase as a determinant of ethanol sensitivity: Relation to NMDA-receptor function
-
Miyakawa, T., Yagi, T., Kitazawa, H., Yasuda, M., Kawai, N., Tsuboi, K., and Niki, H., Fyn-kinase as a determinant of ethanol sensitivity: relation to NMDA-receptor function, Science, 278, 698-701, 1997.
-
(1997)
Science
, vol.278
, pp. 698-701
-
-
Miyakawa, T.1
Yagi, T.2
Kitazawa, H.3
Yasuda, M.4
Kawai, N.5
Tsuboi, K.6
Niki, H.7
-
272
-
-
0028999763
-
Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors
-
Harris, R. A., McQuilkin, S. J., Paylor, R., Abeliovich, A., Tonegawa, S., and Wehner, J. M., Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors, Proc. Natl. Acad. Sci. U.S.A., 92(9), 365g-62, 1995.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, Issue.9
-
-
Harris, R.A.1
McQuilkin, S.J.2
Paylor, R.3
Abeliovich, A.4
Tonegawa, S.5
Wehner, J.M.6
-
273
-
-
0029776391
-
Elevated alcohol consumption in null mutant mice lacking 5-HT1B serotonin receptors
-
Crabbe, J. C., Phillips, T. J., Feller, D. J., Hen, R., Wenger, C. D., Lessov, C. N., and Schafer, G. L., Elevated alcohol consumption in null mutant mice lacking 5-HT1B serotonin receptors, Nat. Genet., 14(1), 98-101, 1996.
-
(1996)
Nat. Genet.
, vol.14
, Issue.1
, pp. 98-101
-
-
Crabbe, J.C.1
Phillips, T.J.2
Feller, D.J.3
Hen, R.4
Wenger, C.D.5
Lessov, C.N.6
Schafer, G.L.7
-
274
-
-
0031825997
-
Neurobiology of stress and cocaine addiction. Studies on corticotropin-releasing factor in rats, monkeys, and humans
-
Sarnyai, Z., Neurobiology of stress and cocaine addiction. Studies on corticotropin-releasing factor in rats, monkeys, and humans, Ann. N. Y. Acad. Sci., 851, 371-387, 1998.
-
(1998)
Ann. N. Y. Acad. Sci.
, vol.851
, pp. 371-387
-
-
Sarnyai, Z.1
-
275
-
-
0032004331
-
Endocrine effects of nicotine administration, tobacco, and other drug withdrawal in humans
-
Pickworth, W. B. and Fant, R. V., Endocrine effects of nicotine administration, tobacco, and other drug withdrawal in humans, Psychoneuroendocrinology, 23(2), 131-141, 1998.
-
(1998)
Psychoneuroendocrinology
, vol.23
, Issue.2
, pp. 131-141
-
-
Pickworth, W.B.1
Fant, R.V.2
-
276
-
-
0029890381
-
Pathophysiological basis of vulnerability to drug abuse: Role of an interaction between stress, glucocorticoids, and dopaminergic neurons
-
Piazza, P. V. and Le Moal, M. L., Pathophysiological basis of vulnerability to drug abuse: role of an interaction between stress, glucocorticoids, and dopaminergic neurons,Annu. Rev. Pharmacol. Toxicol., 36, 359-378, 1996.
-
(1996)
Annu. Rev. Pharmacol. Toxicol.
, vol.36
, pp. 359-378
-
-
Piazza, P.V.1
Le Moal, M.L.2
-
277
-
-
17344362093
-
Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor
-
Timpl, P., Spanagel, R., Sillaber, I., Kresse, A., Reul, J. M., Stalla, G. K., Blanquet, V., Steckler, T., Holsboer, F., and Wurst, W., Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor, Nat. Genet., 19(2), 162-166, 1998.
-
(1998)
Nat. Genet.
, vol.19
, Issue.2
, pp. 162-166
-
-
Timpl, P.1
Spanagel, R.2
Sillaber, I.3
Kresse, A.4
Reul, J.M.5
Stalla, G.K.6
Blanquet, V.7
Steckler, T.8
Holsboer, F.9
Wurst, W.10
-
278
-
-
0029856343
-
Cellular responses to psychomotor stimulant and neuroleptic drugs are abnormal in mice lacking the D1 dopamine receptor
-
Moratalla, R., Xu, M., Tonegawa, S., and Graybiel, A. M., Cellular responses to psychomotor stimulant and neuroleptic drugs are abnormal in mice lacking the D1 dopamine receptor, Proc. Natl. Acad. Sci. U.S.A., 93(25), 14928-14933, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.25
, pp. 14928-14933
-
-
Moratalla, R.1
Xu, M.2
Tonegawa, S.3
Graybiel, A.M.4
-
279
-
-
0029622329
-
Retained cocaine conditioned place preference in D1 receptor deficient mice
-
Miner, L. L., Drago, J., Chamberlain, P. M., Donovan, D., and Uhl, G. R., Retained cocaine conditioned place preference in D1 receptor deficient mice, Neuroreport, 6(17), 2314-2316, 1995.
-
(1995)
Neuroreport
, vol.6
, Issue.17
, pp. 2314-2316
-
-
Miner, L.L.1
Drago, J.2
Chamberlain, P.M.3
Donovan, D.4
Uhl, G.R.5
-
280
-
-
0030843574
-
Absence of opiate rewarding effects in mice lacking dopamine D2 receptors
-
Maldonado, R., Saiardi, A., Valverde, O., Samad, T. A., Roques, B. P., and Borrelli, E., Absence of opiate rewarding effects in mice lacking dopamine D2 receptors, Nature, 388(6642), 586-589, 1997.
-
(1997)
Nature
, vol.388
, Issue.6642
, pp. 586-589
-
-
Maldonado, R.1
Saiardi, A.2
Valverde, O.3
Samad, T.A.4
Roques, B.P.5
Borrelli, E.6
-
281
-
-
85069130593
-
Cocaine and amphetamine reward in VMAT2 and DAT knockout mice: Evidence for transporter-selective effects
-
Sora, I., Takahashi, N., Funada, M., Li, X., Kinsey, S., Lin, Z., Donovan, D., Miner, L., and Uhl, G. R., Cocaine and amphetamine reward in VMAT2 and DAT knockout mice: evidence for transporter-selective effects, Soc. Neurosci. Abstr., 23, 524, 1997.
-
(1997)
Soc. Neurosci. Abstr.
, vol.23
, pp. 524
-
-
Sora, I.1
Takahashi, N.2
Funada, M.3
Li, X.4
Kinsey, S.5
Lin, Z.6
Donovan, D.7
Miner, L.8
Uhl, G.R.9
-
282
-
-
0032082917
-
Cocaine self-administration in dopamine-transporter knockout mice
-
Rocha, B. A., Fumagalli, F. R., Gainetdinov, R., Jones, S. R., Ator, R., Giros, B., Miller, G. W., and Caron, M. G., Cocaine self-administration in dopamine-transporter knockout mice, Nat. Neurosci., 1(2), 132-137, 1998.
-
(1998)
Nat. Neurosci.
, vol.1
, Issue.2
, pp. 132-137
-
-
Rocha, B.A.1
Fumagalli, F.R.2
Gainetdinov, R.3
Jones, S.R.4
Ator, R.5
Giros, B.6
Miller, G.W.7
Caron, M.G.8
-
283
-
-
0030609867
-
5-Hydroxytryptamine1B receptors modulate the effect of cocaine on c-fos expression: Converging evidence using 5-hydroxytryptamine1B knockout mice and the 5-hydroxytryptamine1B/1D antagonist GR127935
-
Lucas, J. J., Segu, L., and Hen, R., 5-Hydroxytryptamine1B receptors modulate the effect of cocaine on c-fos expression: converging evidence using 5-hydroxytryptamine1B knockout mice and the 5-hydroxytryptamine1B/1D antagonist GR127935, Mol. Pharmacol., 51(5), 755-763, 1997.
-
(1997)
Mol. Pharmacol.
, vol.51
, Issue.5
, pp. 755-763
-
-
Lucas, J.J.1
Segu, L.2
Hen, R.3
-
284
-
-
0032080002
-
Type I adenylyl cyclase mutant mice have impaired mossy fiber long-term potentiation
-
Villacres, E. C., Wong, S. T., Chavkin, C., and Storm, D. R., Type I adenylyl cyclase mutant mice have impaired mossy fiber long-term potentiation, J. Neurosci., 18(9), 3186-3194, 1998.
-
(1998)
J. Neurosci.
, vol.18
, Issue.9
, pp. 3186-3194
-
-
Villacres, E.C.1
Wong, S.T.2
Chavkin, C.3
Storm, D.R.4
-
285
-
-
0029047077
-
Effects of kainic acid induced seizures on immediate early gene expression in mice with a targeted mutation of the CREB gene
-
Blendy, J. A., Schmid, W., Kiessling, M., Schutz, G., and Gass, P., Effects of kainic acid induced seizures on immediate early gene expression in mice with a targeted mutation of the CREB gene, Brain Res., 681(1-2), 8-14, 1995.
-
(1995)
Brain Res.
, vol.681
, Issue.1-2
, pp. 8-14
-
-
Blendy, J.A.1
Schmid, W.2
Kiessling, M.3
Schutz, G.4
Gass, P.5
-
286
-
-
0030067803
-
Programmed cell death in the absence of c-Fos and c-Jun
-
Roffler-Tarlov, S., Brown, J. J., Tarlov, E., Stolarov, J., Chapman, D. L., Alexiou, M., and Papaioannou, V. E., Programmed cell death in the absence of c-Fos and c-Jun, Development, 122(1), 1-9, 1996.
-
(1996)
Development
, vol.122
, Issue.1
, pp. 1-9
-
-
Roffler-Tarlov, S.1
Brown, J.J.2
Tarlov, E.3
Stolarov, J.4
Chapman, D.L.5
Alexiou, M.6
Papaioannou, V.E.7
-
287
-
-
0030014237
-
Expression of FosB during mouse development: Normal development of FosB knockout mice
-
Gruda, M. C., van Amsterdam, J., Rizzo, C. A., Durham, S. K., Lira, S., and Bravo, R., Expression of FosB during mouse development: normal development of FosB knockout mice, Oncogene, 12(10), 2177-2185, 1996.
-
(1996)
Oncogene
, vol.12
, Issue.10
, pp. 2177-2185
-
-
Gruda, M.C.1
Van Amsterdam, J.2
Rizzo, C.A.3
Durham, S.K.4
Lira, S.5
Bravo, R.6
-
288
-
-
0029013598
-
Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency
-
Bach, M. E., Hawkins, R. D., Osman, M., Kandel, E. R., and Mayford, M., Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency, Cell, 81(6), 905-915, 1995.
-
(1995)
Cell
, vol.81
, Issue.6
, pp. 905-915
-
-
Bach, M.E.1
Hawkins, R.D.2
Osman, M.3
Kandel, E.R.4
Mayford, M.5
-
289
-
-
0029127955
-
Limbic epilepsy in transgenic mice carrying a Ca2+/ calmodulin-dependent kinase II alpha-subunit mutation
-
Butler, L. S., Silva, A. J., Abeliovich, A., Watanabe, Y., Tonegawa, S., and McNamara, J. O., Limbic epilepsy in transgenic mice carrying a Ca2+/ calmodulin-dependent kinase II alpha-subunit mutation, Proc. Natl. Acad. Sci. U.S.A., 92(15), 6852-6855, 1995.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, Issue.15
, pp. 6852-6855
-
-
Butler, L.S.1
Silva, A.J.2
Abeliovich, A.3
Watanabe, Y.4
Tonegawa, S.5
McNamara, J.O.6
-
290
-
-
0029871928
-
Requirement for alpha-CaMKII in experience-dependent plasticity of the barrel cortex
-
Glazewski, S., Chen, C. M., Silva, A., and Fox, K., Requirement for alpha-CaMKII in experience-dependent plasticity of the barrel cortex, Science, 272(5260), 421-423, 1996.
-
(1996)
Science
, vol.272
, Issue.5260
, pp. 421-423
-
-
Glazewski, S.1
Chen, C.M.2
Silva, A.3
Fox, K.4
-
291
-
-
0030247009
-
Deficient plasticity in the primary visual cortex of alpha-calcium/calmodulin-dependent protein kinase II mutant mice
-
Gordon, J. A., Cioffi, D., Silva, A. J., and Stryker, M. P., Deficient plasticity in the primary visual cortex of alpha-calcium/calmodulin-dependent protein kinase II mutant mice, Neuron, 17(3), 491-499, 1996.
-
(1996)
Neuron
, vol.17
, Issue.3
, pp. 491-499
-
-
Gordon, J.A.1
Cioffi, D.2
Silva, A.J.3
Stryker, M.P.4
-
292
-
-
0030953063
-
Age-dependent decrease of synaptic plasticity in the neocortex of alphaCaMKII mutant mice
-
Kirkwood, A., Silva, A., and Bear, M. F., Age-dependent decrease of synaptic plasticity in the neocortex of alphaCaMKII mutant mice, Proc. Natl. Acad. Sci. U.S.A., 94(7), 3380-3383, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.7
, pp. 3380-3383
-
-
Kirkwood, A.1
Silva, A.2
Bear, M.F.3
-
293
-
-
0028114735
-
Abnormal fear response and aggressive behavior in mutant mice deficient for alpha-calcium-calmodulin kinase II
-
Chen, C., Rainnie, D. G., Greene, R. W., and Tonegawa, S., Abnormal fear response and aggressive behavior in mutant mice deficient for alpha-calcium-calmodulin kinase II, Science, 266(5183), 291-294, 1994.
-
(1994)
Science
, vol.266
, Issue.5183
, pp. 291-294
-
-
Chen, C.1
Rainnie, D.G.2
Greene, R.W.3
Tonegawa, S.4
-
294
-
-
0030066622
-
Ischemia-induced neuronal damage: A role for calcium/calmodulin-dependent protein kinase II
-
Waxham, M. N., Grotta, J. C., Silva, A. J., Strong, R., and Aronowski, J., Ischemia-induced neuronal damage: a role for calcium/calmodulin-dependent protein kinase II, J. Cereb. Blood Flow Metab., 16(1), 1-6, 1996.
-
(1996)
J. Cereb. Blood Flow Metab.
, vol.16
, Issue.1
, pp. 1-6
-
-
Waxham, M.N.1
Grotta, J.C.2
Silva, A.J.3
Strong, R.4
Aronowski, J.5
-
295
-
-
0029620817
-
Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice
-
Chen, C., Kano, M., Abeliovich, A., Chen, L., Bao, S., Kim, J. J., Hashimoto, K., Thompson, R. F., and Tonegawa, S., Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice, Cell, 83(7), 1233-1242, 1995.
-
(1995)
Cell
, vol.83
, Issue.7
, pp. 1233-1242
-
-
Chen, C.1
Kano, M.2
Abeliovich, A.3
Chen, L.4
Bao, S.5
Kim, J.J.6
Hashimoto, K.7
Thompson, R.F.8
Tonegawa, S.9
-
296
-
-
0030930754
-
Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase
-
Burton, K. A., Johnson, B. D., Hausken, Z. E., Westenbroek, R. E., Idzerda, R. L., Scheuer, T., Scott, J. D., Catterall, W. A., and McKnight, G. S., Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase, Proc. Natl. Acad. Sci. U.S.A., 94(20), 11067-11072, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.20
, pp. 11067-11072
-
-
Burton, K.A.1
Johnson, B.D.2
Hausken, Z.E.3
Westenbroek, R.E.4
Idzerda, R.L.5
Scheuer, T.6
Scott, J.D.7
Catterall, W.A.8
McKnight, G.S.9
-
297
-
-
0030717501
-
Loss of haloperidol induced gene expression and catalepsy in protein kinase A-deficient mice
-
Adams, M. R., Brandon, E. P., Chartoff, E. H., Idzerda, R. L., Dorsa, D. M., and McKnight, G. S., Loss of haloperidol induced gene expression and catalepsy in protein kinase A-deficient mice, Proc. Natl. Acad. Sci. U.S.A., 94(22), 12157-12161, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.22
, pp. 12157-12161
-
-
Adams, M.R.1
Brandon, E.P.2
Chartoff, E.H.3
Idzerda, R.L.4
Dorsa, D.M.5
McKnight, G.S.6
-
298
-
-
0032525114
-
Defective motor behavior and neural gene expression in RIIbeta-protein kinase A mutant mice
-
Brandon, E. P., Logue, S. F., Adams, M. R., Qi, M., Sullivan, S. P., Matsumoto, A. M., Dorsa, D. M., Wehner, J. M., McKnight, G. S., and Idzerda, R. L., Defective motor behavior and neural gene expression in RIIbeta-protein kinase A mutant mice, J. Neurosci., 18(10), 3639-3649 1998.
-
(1998)
J. Neurosci.
, vol.18
, Issue.10
, pp. 3639-3649
-
-
Brandon, E.P.1
Logue, S.F.2
Adams, M.R.3
Qi, M.4
Sullivan, S.P.5
Matsumoto, A.M.6
Dorsa, D.M.7
Wehner, J.M.8
McKnight, G.S.9
Idzerda, R.L.10
-
299
-
-
0029737861
-
Genetically lean mice result from targeted disruption of the RII beta subunit of protein kinase A
-
Cummings, D. E., Brandon, E. P., Planas, J. V., Motamed, K., Idzerda, R. L., and McKnight, G. S., Genetically lean mice result from targeted disruption of the RII beta subunit of protein kinase A, Nature, 382(6592), 622-626, 1996.
-
(1996)
Nature
, vol.382
, Issue.6592
, pp. 622-626
-
-
Cummings, D.E.1
Brandon, E.P.2
Planas, J.V.3
Motamed, K.4
Idzerda, R.L.5
McKnight, G.S.6
-
300
-
-
0029773649
-
Taste aversion learning in fyn mutant mice
-
Schafe, G. E., Stein, P. L., Park, C. R., and Bernstein, I. L., Taste aversion learning in fyn mutant mice, Behav. Neurosci., 110(4), 845-848, 1996.
-
(1996)
Behav. Neurosci.
, vol.110
, Issue.4
, pp. 845-848
-
-
Schafe, G.E.1
Stein, P.L.2
Park, C.R.3
Bernstein, I.L.4
-
301
-
-
0028804107
-
Fyn tyrosine kinase is required for normal amygdala kindling
-
Cain, D. P., Grant, S. G., Saucier, D., Hargreaves, E. L., and Kandel, E. R., Fyn tyrosine kinase is required for normal amygdala kindling, Epilepsy Res., 22(2) 107-114, 1995.
-
(1995)
Epilepsy Res.
, vol.22
, Issue.2
, pp. 107-114
-
-
Cain, D.P.1
Grant, S.G.2
Saucier, D.3
Hargreaves, E.L.4
Kandel, E.R.5
-
302
-
-
0029768093
-
Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology, and perinatal death
-
Ohshima, T., Ward, J. M., Huh, C. G., Longenecker, G., Veeranna, Pant, H. C., Brady, R. O., Martin, L. J., and Kulkarni, A. B., Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology, and perinatal death, Proc. Natl. Acad. Sci. U.S.A., 93(20), 11173-11178, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.20
, pp. 11173-11178
-
-
Ohshima, T.1
Ward, J.M.2
Huh, C.G.3
Longenecker, G.4
Veeranna5
Pant, H.C.6
Brady, R.O.7
Martin, L.J.8
Kulkarni, A.B.9
-
303
-
-
0030845179
-
G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization
-
Peppel, K., Boekhoff, I., McDonald, P., Breer, H., Caron, M. G., and Lefkowitz, R. J., G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization, J. Biol. Chem., 272(41), 25425-25428, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, Issue.41
, pp. 25425-25428
-
-
Peppel, K.1
Boekhoff, I.2
McDonald, P.3
Breer, H.4
Caron, M.G.5
Lefkowitz, R.J.6
-
304
-
-
0030780804
-
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the jnk3 gene
-
Yang, D. D., Kuan, C. Y., Whitmarsh, A. J., Rincon, M., Zheng, T. S., Davis, R. J., Rakic, P., and Flavell, R. A., Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the jnk3 gene, Nature, 389(6653), 865-870, 1997.
-
(1997)
Nature
, vol.389
, Issue.6653
, pp. 865-870
-
-
Yang, D.D.1
Kuan, C.Y.2
Whitmarsh, A.J.3
Rincon, M.4
Zheng, T.S.5
Davis, R.J.6
Rakic, P.7
Flavell, R.A.8
-
305
-
-
0028075683
-
Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C
-
Li, C., Takei, K., Geppert, M., Daniell, L., Stenius, K., Chapman, E. R.,
-
(1994)
Neuron
, vol.13
, Issue.4
, pp. 885-898
-
-
Li, C.1
Takei, K.2
Geppert, M.3
Daniell, L.4
Stenius, K.5
Chapman, E.R.6
Jahn, R.7
De Camilli, P.8
Sudhof, T.C.9
-
306
-
-
0031035031
-
Persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking mGluR1
-
Kano, M., Hashimoto, K., Kurihara, H., Watanabe, M., Inoue, Y., Aiba, A., and Tonegawa, S., Persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking mGluR1, Neuron, 18(1), 71-79, 1997.
-
(1997)
Neuron
, vol.18
, Issue.1
, pp. 71-79
-
-
Kano, M.1
Hashimoto, K.2
Kurihara, H.3
Watanabe, M.4
Inoue, Y.5
Aiba, A.6
Tonegawa, S.7
-
307
-
-
0029121640
-
Inactivation in vivo of metabotropic glutamate receptor 1 by specific chromosomal insertion of reporter gene lacZ
-
Conquet, F., Inactivation in vivo of metabotropic glutamate receptor 1 by specific chromosomal insertion of reporter gene lacZ, Neuropharmacology, 34(8), 865-870, 1995.
-
(1995)
Neuropharmacology
, vol.34
, Issue.8
, pp. 865-870
-
-
Conquet, F.1
-
308
-
-
0028937683
-
Specific deficit of the on response in visual transmission by targeted disruption of the mGluR6 gene
-
Masu, M., Iwakabe, H., Tagawa, Y., Miyoshi, T., Yamashita, M., Fukuda, Y., Sasaki, H., Hiroi, K., Nakamura, Y., Shigemoto, R., Takada, M., Nakamura, K., Nakao, K., Katsuki, M., and Nakanishi, S., Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene, Cell, 80(5), 757-765, 1995.
-
(1995)
Cell
, vol.80
, Issue.5
, pp. 757-765
-
-
Masu, M.1
Iwakabe, H.2
Tagawa, Y.3
Miyoshi, T.4
Yamashita, M.5
Fukuda, Y.6
Sasaki, H.7
Hiroi, K.8
Nakamura, Y.9
Shigemoto, R.10
Takada, M.11
Nakamura, K.12
Nakao, K.13
Katsuki, M.14
Nakanishi, S.15
-
309
-
-
0030439806
-
Hippocampal CA1-region-restricted knockout of NMDAR1 gene disrupts synaptic plasticity, place fields, and spatial learning
-
Tonegawa, S., Tsien, J. Z., McHugh, T. J., Huerta, P., Blum, K. I., and Wilson, M. A., Hippocampal CA1-region-restricted knockout of NMDAR1 gene disrupts synaptic plasticity, place fields, and spatial learning, Cold Spring Harbor Symp. Quant. Biol., 61, 225-238, 1996.
-
(1996)
Cold Spring Harbor Symp. Quant. Biol.
, vol.61
, pp. 225-238
-
-
Tonegawa, S.1
Tsien, J.Z.2
McHugh, T.J.3
Huerta, P.4
Blum, K.I.5
Wilson, M.A.6
-
310
-
-
13344269673
-
Deficient cerebellar long-term depression, impaired eyeblink conditioning, and normal motor coordination in GFAP mutant mice
-
Shibuki, K., Gomi, H., Chen, L., Bao, S., Kim, J. J., Wakatsuki, H., Fujisaki, T., Fujimoto, K., Katoh, A., Ikeda, T., Chen, C., Thompson, R. F., and Itohara, S., Deficient cerebellar long-term depression, impaired eyeblink conditioning, and normal motor coordination in GFAP mutant mice, Neuron, 16(3), 587-599, 1996.
-
(1996)
Neuron
, vol.16
, Issue.3
, pp. 587-599
-
-
Shibuki, K.1
Gomi, H.2
Chen, L.3
Bao, S.4
Kim, J.J.5
Wakatsuki, H.6
Fujisaki, T.7
Fujimoto, K.8
Katoh, A.9
Ikeda, T.10
Chen, C.11
Thompson, R.F.12
Itohara, S.13
-
311
-
-
0030867989
-
Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning
-
Schwartz, P. M., Borghesani, P. R., Levy, R. L., Pomeroy, S. L., and Segal, R. A., Abnormal cerebellar development and foliation in BDNF-/-mice reveals a role for neurotrophins in CNS patterning, Neuron, 19(2), 269-281, 1997.
-
(1997)
Neuron
, vol.19
, Issue.2
, pp. 269-281
-
-
Schwartz, P.M.1
Borghesani, P.R.2
Levy, R.L.3
Pomeroy, S.L.4
Segal, R.A.5
-
312
-
-
9044254932
-
Impaired motor learning performance in cerebellar En-2 mutant mice
-
Gerlai, R., Millen, K. J., Herrup, K., Fabien, K., Joyner, A. L., and Roder, J., Impaired motor learning performance in cerebellar En-2 mutant mice, Behav. Neurosci., 110(1), 126-133, 1996.
-
(1996)
Behav. Neurosci.
, vol.110
, Issue.1
, pp. 126-133
-
-
Gerlai, R.1
Millen, K.J.2
Herrup, K.3
Fabien, K.4
Joyner, A.L.5
Roder, J.6
-
313
-
-
0031019589
-
Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene
-
Airaksinen, M. S., Eilers, J., Garaschuk, O., Thoenen, H., Konnerth, A., and Meyer, M., Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene, Proc. Natl. Acad. Sci. U.S.A., 94(4), 1488-1493, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.4
, pp. 1488-1493
-
-
Airaksinen, M.S.1
Eilers, J.2
Garaschuk, O.3
Thoenen, H.4
Konnerth, A.5
Meyer, M.6
-
314
-
-
13344282734
-
Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene
-
Sakaguchi, S., Katamine, S., Nishida, N., Moriuchi, R., Shigematsu, K., Sugimoto, T., Nakatani, A., Kataoka, Y., Houtani, T., Shirabe, S., Okada, H., Hasegawa, S., Miyamoto, T., and Noda, T., Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene, Nature, 380(6574), 528-531, 1996.
-
(1996)
Nature
, vol.380
, Issue.6574
, pp. 528-531
-
-
Sakaguchi, S.1
Katamine, S.2
Nishida, N.3
Moriuchi, R.4
Shigematsu, K.5
Sugimoto, T.6
Nakatani, A.7
Kataoka, Y.8
Houtani, T.9
Shirabe, S.10
Okada, H.11
Hasegawa, S.12
Miyamoto, T.13
Noda, T.14
-
315
-
-
0029664444
-
Role of the D1A dopamine receptor in the pathogenesis of genetic hypertension
-
Albrecht, F. E., Drago, J., Felder, R. A., Printz, M. P., Eisner, G. M., Robillard, J. E., Sibley, D. R., Westphal, H. J., and Jose, P. A., Role of the D1A dopamine receptor in the pathogenesis of genetic hypertension, J. Clin. Invest., 97(10), 2283-2288, 1996.
-
(1996)
J. Clin. Invest.
, vol.97
, Issue.10
, pp. 2283-2288
-
-
Albrecht, F.E.1
Drago, J.2
Felder, R.A.3
Printz, M.P.4
Eisner, G.M.5
Robillard, J.E.6
Sibley, D.R.7
Westphal, H.J.8
Jose, P.A.9
-
316
-
-
0028589325
-
Altered striatal function in a mutant mouse lacking D1a dopamine receptors
-
Drago, J., Gerfen, C. R., Lachowicz, J. E., Steiner, H., Hollon, T. R., Love, P. E., Ooi, G. T., Grinberg, A., Lee, E. J., Huang, S. P., Bartlett, P. F., Jose, P. A., Sibley, D. R., and Westphal, H., Altered striatal function in a mutant mouse lacking D1A dopamine receptors, Proc. Natl. Acad. Sci. U.S.A., 91(26), 12564-12568, 1994.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, Issue.26
, pp. 12564-12568
-
-
Drago, J.1
Gerfen, C.R.2
Lachowicz, J.E.3
Steiner, H.4
Hollon, T.R.5
Love, P.E.6
Ooi, G.T.7
Grinberg, A.8
Lee, E.J.9
Huang, S.P.10
Bartlett, P.F.11
Jose, P.A.12
Sibley, D.R.13
Westphal, H.14
-
317
-
-
0029811947
-
Modulatory actions of dopamine on NMDA receptor-mediated responses are reduced in D1A-deficient mutant mice
-
Levine, M. S., Altemus, K. L., Cepeda, C., Cromwell, H. C., Crawford, C., Ariano, M. A., Drago, J., Sibley, D. R., and Westphal, H., Modulatory actions of dopamine on NMDA receptor-mediated responses are reduced in D1A-deficient mutant mice, J. Neurosci., 16(18), 5870-5882, 1996
-
(1996)
J. Neurosci.
, vol.16
, Issue.18
, pp. 5870-5882
-
-
Levine, M.S.1
Altemus, K.L.2
Cepeda, C.3
Cromwell, H.C.4
Crawford, C.5
Ariano, M.A.6
Drago, J.7
Sibley, D.R.8
Westphal, H.9
-
318
-
-
0028605680
-
Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice
-
Xu, M., Hu, X. T., Cooper, D. C., Moratalla, R., Graybiel, A. M., White, F. J., and Tonegawa, S., Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice, Cell, 79(6), 945-955, 1994.
-
(1994)
Cell
, vol.79
, Issue.6
, pp. 945-955
-
-
Xu, M.1
Hu, X.T.2
Cooper, D.C.3
Moratalla, R.4
Graybiel, A.M.5
White, F.J.6
Tonegawa, S.7
-
319
-
-
0030614860
-
D1-like dopaminergic activation of phosphoinositide hydrolysis is independent of D1A dopamine receptors: Evidence from D1A knockout mice
-
Friedman, E., Jin, L. Q., Cai, G. P., Hollon, T. R., Drago, J., Sibley, D. R., and Wang, H. Y., D1-like dopaminergic activation of phosphoinositide hydrolysis is independent of D1A dopamine receptors: evidence from D1A knockout mice, Mol. Pharmacol., 51(1), 6-11, 1997.
-
(1997)
Mol. Pharmacol.
, vol.51
, Issue.1
, pp. 6-11
-
-
Friedman, E.1
Jin, L.Q.2
Cai, G.P.3
Hollon, T.R.4
Drago, J.5
Sibley, D.R.6
Wang, H.Y.7
-
320
-
-
0030780877
-
Dopamine D3 receptor mutant mice exhibit increased behavioral sensitivity to concurrent stimulation of D1 and D2 receptors
-
Xu, M., Koeltzow, T. E., Santiago, G. T., Moratalla, R., Cooper, D. C., Hu, X. T., White, N. M., Graybiel, A. M., White, F. J., and Tonegawa, S., Dopamine D3 receptor mutant mice exhibit increased behavioral sensitivity to concurrent stimulation of D1 and D2 receptors, Neuron, 19(4), 837-848, 1997.
-
(1997)
Neuron
, vol.19
, Issue.4
, pp. 837-848
-
-
Xu, M.1
Koeltzow, T.E.2
Santiago, G.T.3
Moratalla, R.4
Cooper, D.C.5
Hu, X.T.6
White, N.M.7
Graybiel, A.M.8
White, F.J.9
Tonegawa, S.10
-
321
-
-
0030877835
-
Dopamine transporter is required for in vivo MPTP neurotoxicity: Evidence from mice lacking the transporter
-
Gainetdinov, R. R., Fumagalli, F., Jones, S. R., and Caron, M. G., Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter, J. Neurochem., 69(3), 1322-1325, 1997.
-
(1997)
J. Neurochem.
, vol.69
, Issue.3
, pp. 1322-1325
-
-
Gainetdinov, R.R.1
Fumagalli, F.2
Jones, S.R.3
Caron, M.G.4
-
322
-
-
0031016163
-
+ channel GIRK2
-
+ channel GIRK2, Proc. Natl. Acad. Sci. U.S.A., 94(3), 923-927, 1997.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, Issue.3
, pp. 923-927
-
-
Signorini, S.1
Liso, Y.J.2
Duncan, S.A.3
Jan, L.Y.4
Stoffel, M.5
-
323
-
-
0029820548
-
Epilepsy and brain abnormalities in mice lacking the Otx1 gene
-
Acampora, D., Mazan, S., Avantaggiato, V., Barone, P., Tuorto, F., Lallemand, Y., Brulet, P., and Simeone, A., Epilepsy and brain abnormalities in mice lacking the Otx1 gene, Nat. Genet, 14(2), 218-222, 1996.
-
(1996)
Nat. Genet
, vol.14
, Issue.2
, pp. 218-222
-
-
Acampora, D.1
Mazan, S.2
Avantaggiato, V.3
Barone, P.4
Tuorto, F.5
Lallemand, Y.6
Brulet, P.7
Simeone, A.8
-
324
-
-
0031018336
-
Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality
-
Chae, T., Kwon, Y. T., Bronson, R., Dikkes, P., Li, E., and Tsai, L. H., Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality, Neuron, 18(1), 29-42, 1997.
-
(1997)
Neuron
, vol.18
, Issue.1
, pp. 29-42
-
-
Chae, T.1
Kwon, Y.T.2
Bronson, R.3
Dikkes, P.4
Li, E.5
Tsai, L.H.6
-
325
-
-
0031016825
-
Disruption of the metallothionein-III gene in mice: Analysis of brain zinc, behavior, and neuron vulnerability to metals, aging, and seizures
-
Erickson, J. C., Hollopeter, G., Thomas, S. A., Froelick, G. J., and Palmiter, R. D., Disruption of the metallothionein-III gene in mice: analysis of brain zinc, behavior, and neuron vulnerability to metals, aging, and seizures, J. Neurosci., 17(4), 1271-1281, 1997.
-
(1997)
J. Neurosci.
, vol.17
, Issue.4
, pp. 1271-1281
-
-
Erickson, J.C.1
Hollopeter, G.2
Thomas, S.A.3
Froelick, G.J.4
Palmiter, R.D.5
-
326
-
-
0029899586
-
Altered neuronal and microglial responses to excitotoxic and ischemie brain injury in mice lacking TNF receptors
-
Bruce, A. J., Boling, W., Kindy, M. S., Peschon, J., Kraemer, P. J., Carpenter, M. K., Holtsberg, F. W., and Mattson, M. P., Altered neuronal and microglial responses to excitotoxic and ischemie brain injury in mice lacking TNF receptors, Nat. Med., 2(7), 788-794, 1996.
-
(1996)
Nat. Med.
, vol.2
, Issue.7
, pp. 788-794
-
-
Bruce, A.J.1
Boling, W.2
Kindy, M.S.3
Peschon, J.4
Kraemer, P.J.5
Carpenter, M.K.6
Holtsberg, F.W.7
Mattson, M.P.8
-
327
-
-
0029915857
-
Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death
-
Morrison, R.S., Wenzel, H.J., Kinoshita, Y., Robbins, C. A., Donehower, L. A., and Schwartzkroin, P. A., Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death, J. Neurosci., 16(4), 1337-1345, 1996.
-
(1996)
J. Neurosci.
, vol.16
, Issue.4
, pp. 1337-1345
-
-
Morrison, R.S.1
Wenzel, H.J.2
Kinoshita, Y.3
Robbins, C.A.4
Donehower, L.A.5
Schwartzkroin, P.A.6
-
328
-
-
0030816051
-
Altered pain perception and inflammatory response in mice lacking prostacyclin receptor
-
Murata, T., Ushikubi, F., Matsuoka, T., Hirata, M., Yamasaki, A., Sugimoto, Y., Ichikawa, A., Aze, Y., Tanaka, T., Yoshida, N., Ueno, A., Ohishi, S., and Narumiya, S., Altered pain perception and inflammatory response in mice lacking prostacyclin receptor, Nature, 388(6643), 678-682, 1997.
-
(1997)
Nature
, vol.388
, Issue.6643
, pp. 678-682
-
-
Murata, T.1
Ushikubi, F.2
Matsuoka, T.3
Hirata, M.4
Yamasaki, A.5
Sugimoto, Y.6
Ichikawa, A.7
Aze, Y.8
Tanaka, T.9
Yoshida, N.10
Ueno, A.11
Ohishi, S.12
Narumiya, S.13
-
329
-
-
0031441582
-
Nociceptive responses in interleukin-6-deficient mice to peripheral inflammation and peripheral nerve section
-
Xu, X. J., Hao, J. X., Andell-Jonsson, S., Poll, V., Bartfai, T., and Wiesenfeld-Hallin, Z., Nociceptive responses in interleukin-6-deficient mice to peripheral inflammation and peripheral nerve section, Cytokine, 9(12), 1028-1033, 1997.
-
(1997)
Cytokine
, vol.9
, Issue.12
, pp. 1028-1033
-
-
Xu, X.J.1
Hao, J.X.2
Andell-Jonsson, S.3
Poll, V.4
Bartfai, T.5
Wiesenfeld-Hallin, Z.6
-
330
-
-
0030175399
-
Nociception and inflammatory hyperalgesia in B2 bradykinin receptor knockout mice
-
Boyce, S., Rupniak, N. M., Carlson, E. J., Webb, J., Borkowski, J. A., Hess, J. F., Strader, C. D., and Hill, R. G., Nociception and inflammatory hyperalgesia in B2 bradykinin receptor knockout mice, Immunopharmacology, 33(1-3), 333-335, 1996.
-
(1996)
Immunopharmacology
, vol.33
, Issue.1-3
, pp. 333-335
-
-
Boyce, S.1
Rupniak, N.M.2
Carlson, E.J.3
Webb, J.4
Borkowski, J.A.5
Hess, J.F.6
Strader, C.D.7
Hill, R.G.8
-
331
-
-
0030611506
-
Effects of the bradykinin B1 receptor antagonist des-Arg9[Leu8]bradykinin and genetic disruption of the B2 receptor on nociception in rats and mice
-
Rupniak, N. M., Boyce, S., Webb, J. K., Williams, A. R., Carlson, E. J., Hill, R. G., Borkowski, J. A., and Hess, J. F., Effects of the bradykinin B1 receptor antagonist des-Arg9[Leu8]bradykinin and genetic disruption of the B2 receptor on nociception in rats and mice, Pain, 71(1), 89-97, 1997.
-
(1997)
Pain
, vol.71
, Issue.1
, pp. 89-97
-
-
Rupniak, N.M.1
Boyce, S.2
Webb, J.K.3
Williams, A.R.4
Carlson, E.J.5
Hill, R.G.6
Borkowski, J.A.7
Hess, J.F.8
-
332
-
-
0030479642
-
The involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experiments
-
Korte, M., Staiger, V., Griesbeck, O., Thoenen, H., and Bonhoeffer, T., The involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experiments, J. Physiol Paris, 90(3-4), 157-164, 1996.
-
(1996)
J. Physiol Paris
, vol.90
, Issue.3-4
, pp. 157-164
-
-
Korte, M.1
Staiger, V.2
Griesbeck, O.3
Thoenen, H.4
Bonhoeffer, T.5
-
333
-
-
0027955570
-
Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning
-
Cremer, H., Lange, R., Christoph, A., Plomann, M., Vopper, G., Roes, J., Brown, R., Baldwin, S., Kraemer, P., Scheff, S., Barthels, D., Rajewsky, K., and Wille, W., Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning, Nature, 367(6462), 455-459, 1994.
-
(1994)
Nature
, vol.367
, Issue.6462
, pp. 455-459
-
-
Cremer, H.1
Lange, R.2
Christoph, A.3
Plomann, M.4
Vopper, G.5
Roes, J.6
Brown, R.7
Baldwin, S.8
Kraemer, P.9
Scheff, S.10
Barthels, D.11
Rajewsky, K.12
Wille, W.13
-
334
-
-
0030432491
-
NCAM is essential for axonal growth and fasciculation in the hippocampus
-
Cremer, H., Chazal, G., Goridis, C., and Represa, A., NCAM is essential for axonal growth and fasciculation in the hippocampus, Mol. Cell. Neurosci., 8(5), 323-335, 1997.
-
(1997)
Mol. Cell. Neurosci.
, vol.8
, Issue.5
, pp. 323-335
-
-
Cremer, H.1
Chazal, G.2
Goridis, C.3
Represa, A.4
-
335
-
-
0030245812
-
PSA-NCAM is required for activity-induced synaptic plasticity
-
Muller, D., Wang, C., Skibo, G., Toni, N., Cremer, H., Calaora, V., Rougon, G., and Kiss, J. Z., PSA-NCAM is required for activity-induced synaptic plasticity, Neuron, 17(3), 413-422, 1996.
-
(1996)
Neuron
, vol.17
, Issue.3
, pp. 413-422
-
-
Muller, D.1
Wang, C.2
Skibo, G.3
Toni, N.4
Cremer, H.5
Calaora, V.6
Rougon, G.7
Kiss, J.Z.8
-
336
-
-
9444240943
-
Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber path ways
-
Huang, Y. Y., Bach, M. E., Lipp, H. P., Zhuo, M., Wolfer, D. P., Hawkins, R. D., Schoonjans, L., Kandel, E. R., Godfraind, J. M., Mulligan, R., Collen, D., and Carmeliet, P., Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber path ways, Proc. Natl. Acad. Sci. U.S.A., 93(16), 8699-8704, 1996.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, Issue.16
, pp. 8699-8704
-
-
Huang, Y.Y.1
Bach, M.E.2
Lipp, H.P.3
Zhuo, M.4
Wolfer, D.P.5
Hawkins, R.D.6
Schoonjans, L.7
Kandel, E.R.8
Godfraind, J.M.9
Mulligan, R.10
Collen, D.11
Carmeliet, P.12
-
337
-
-
0029924091
-
A different form of long-lasting potentiation revealed in tissue plasminogen activator mutant mice
-
Frey, U., Muller, M., and Kuhl, D., A different form of long-lasting potentiation revealed in tissue plasminogen activator mutant mice, J. Neurosci., 16(6), 2057-2063, 1996.
-
(1996)
J. Neurosci.
, vol.16
, Issue.6
, pp. 2057-2063
-
-
Frey, U.1
Muller, M.2
Kuhl, D.3
|