-
1
-
-
0023755696
-
Oligodeoxynucleoside phosphoramidites and phosphorothioates as inhibitors of human immunodeficiency virus
-
Agrawal S, Goodchild J, Civeira MP, Thornton AT, Sarin PM, Zamecnik P C (1988) Oligodeoxynucleoside phosphoramidites and phosphorothioates as inhibitors of human immunodeficiency virus. Proc Nat Acad Sci USA 85: 7079-7083
-
(1988)
Proc Nat Acad Sci USA
, vol.85
, pp. 7079-7083
-
-
Agrawal, S.1
Goodchild, J.2
Civeira, M.P.3
Thornton, A.T.4
Sarin, P.M.5
Zamecnik, P.C.6
-
2
-
-
0025743216
-
Pharmacokinetics, biodistribution and stability of oligodeoxynucleotide phosphorothioates in mice
-
Agrawal S, Temsamani J, Tang JY (1991) Pharmacokinetics, biodistribution and stability of oligodeoxynucleotide phosphorothioates in mice. Proc Nat Acad Sci USA 88: 7595-7599
-
(1991)
Proc Nat Acad Sci USA
, vol.88
, pp. 7595-7599
-
-
Agrawal, S.1
Temsamani, J.2
Tang, J.Y.3
-
3
-
-
0028157404
-
Specific inhibition of endogenous neuropeptide Ysynthesis in arcuate nucleus by antisense oligonucleotides suppresses feeding behaviour and insulin secretion
-
Akabayashi A, Wahlestedt C, Alexander JT, Leibowitz SF (1994) Specific inhibition of endogenous neuropeptide Ysynthesis in arcuate nucleus by antisense oligonucleotides suppresses feeding behaviour and insulin secretion. Mol Brain Res 21: 55-61
-
(1994)
Mol Brain Res
, vol.21
, pp. 55-61
-
-
Akabayashi, A.1
Wahlestedt, C.2
Alexander, J.T.3
Leibowitz, S.F.4
-
4
-
-
0028785122
-
Inhibition of human immunodeficiency virus type 1 (HIV) gag gene expression by an antisense oligodeoxynucleotide phosphorothioate
-
Anazodo M I, Wainberg M A, Friesen A D, Wright J A (1995) Inhibition of human immunodeficiency virus type 1 (HIV) gag gene expression by an antisense oligodeoxynucleotide phosphorothioate. Leukaemia 9 (Suppl. 1): S86-S88
-
(1995)
Leukaemia
, vol.9
, Issue.1 SUPPL.
-
-
Anazodo, M.I.1
Wainberg, M.A.2
Friesen, A.D.3
Wright, J.A.4
-
5
-
-
0028220670
-
Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides
-
Bennett C F, CondonT P, Grimm S, Chan H, Chain M-Y (1994) Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides. J Immunol 152: 3530-3540
-
(1994)
J Immunol
, vol.152
, pp. 3530-3540
-
-
Bennett, C.F.1
Condont, P.2
Grimm, S.3
Chan, H.4
Chain, M.-Y.5
-
7
-
-
0028618619
-
Design and application of antisense oligonucleotides in cell culture, in vivo and as therapeutic agents
-
Brysch W, Schlingensiepen K-H (1994) Design and application of antisense oligonucleotides in cell culture, in vivo and as therapeutic agents. Cell Mol Neurobiol 14: 555-567
-
(1994)
Cell Mol Neurobiol
, vol.14
, pp. 555-567
-
-
Brysch, W.1
Schlingensiepen, K.-H.2
-
8
-
-
0025346998
-
Oligodeoxynucleoside phosphorothioate stability in subcellular extracts, culture media, sera and cerebrospinal fluid
-
Campbell JM, Bacon TA, Wickstrom E (1990) Oligodeoxynucleoside phosphorothioate stability in subcellular extracts, culture media, sera and cerebrospinal fluid. J Biochem Biophys Meth 20: 259-267
-
(1990)
J Biochem Biophys Meth
, vol.20
, pp. 259-267
-
-
Campbell, J.M.1
Bacon, T.A.2
Wickstrom, E.3
-
10
-
-
0028985401
-
An antisense oligodeoxynucleotide to μ-opioid receptors inhibit μ-opioid receptor agonist-induced analgesia in rats
-
Chen X-H, Adams J U, Geller E B, DeRiel J K, Adler M A, Liu-Chen L-Y (1995) An antisense oligodeoxynucleotide to μ-opioid receptors inhibit μ-opioid receptor agonist-induced analgesia in rats. Eur J Pharmac 275: 105-108
-
(1995)
Eur J Pharmac
, vol.275
, pp. 105-108
-
-
Chen, X.-H.1
Adams, J.U.2
Geller, E.B.3
DeRiel, J.K.4
Adler, M.A.5
Liu-Chen, L.-Y.6
-
12
-
-
0028609733
-
The application of antisense oligonucleotide technology to the brain: Some pitfalls
-
Chiasson B J, Armstrong J N, Hooper M L, Murphy P R, Robertson H A (1994) The application of antisense oligonucleotide technology to the brain: some pitfalls. Cell Mol Neurobiol 14:507-521
-
(1994)
Cell Mol Neurobiol
, vol.14
, pp. 507-521
-
-
Chiasson, B.J.1
Armstrong, J.N.2
Hooper, M.L.3
Murphy, P.R.4
Robertson, H.A.5
-
13
-
-
0026052924
-
Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms
-
Chiang M Y, Chan H, Zounes M A, Freier S M, Lima W F, Bennett C F (1991) Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms. J Biol Chem 266: 162-171
-
(1991)
J Biol Chem
, vol.266
, pp. 162-171
-
-
Chiang, M.Y.1
Chan, H.2
Zounes, M.A.3
Freier, S.M.4
Lima, W.F.5
Bennett, C.F.6
-
14
-
-
0028207063
-
Blockade of U50, 488H analgesia by antisense oligodeoxynucleotides to a κ-opioid receptor
-
Chien C C, Brown G, Pan X-Y, Pasternak G W (1994) Blockade of U50, 488H analgesia by antisense oligodeoxynucleotides to a κ-opioid receptor. Eur J Pharmac 253: R7-8
-
(1994)
Eur J Pharmac
, vol.253
-
-
Chien, C.C.1
Brown, G.2
Pan, X.-Y.3
Pasternak, G.W.4
-
15
-
-
0026721173
-
Therapeutic applications of oligonucleotides
-
Cooke S T (1992) Therapeutic applications of oligonucleotides. Ann Rev Pharmac Toxicol 32: 329-376
-
(1992)
Ann Rev Pharmac Toxicol
, vol.32
, pp. 329-376
-
-
Cooke, S.T.1
-
16
-
-
0026535166
-
The role of the amygdala in fear and anxiety
-
Davis M (1992) The role of the amygdala in fear and anxiety. Ann Rev Neurosci 15: 353-375
-
(1992)
Ann Rev Neurosci
, vol.15
, pp. 353-375
-
-
Davis, M.1
-
18
-
-
0027788090
-
C-fos antisense generates apomorphine and amphetamine-induced rotation
-
Dragunow M, Lawlor P, Chaisson B, Robertson H (1993) C-fos antisense generates apomorphine and amphetamine-induced rotation. Neuroreport 5: 305-306
-
(1993)
Neuroreport
, vol.5
, pp. 305-306
-
-
Dragunow, M.1
Lawlor, P.2
Chaisson, B.3
Robertson, H.4
-
19
-
-
0025241288
-
Physiological and behavioural response to corticotropin-releasing factor administration: Is CRF a mediator of anxiety or stress response?
-
Dunn A J, Berridge C W (1990) Physiological and behavioural response to corticotropin-releasing factor administration: Is CRF a mediator of anxiety or stress response? Brain Res Rev 15: 71-100
-
(1990)
Brain Res Rev
, vol.15
, pp. 71-100
-
-
Dunn, A.J.1
Berridge, C.W.2
-
20
-
-
0004087819
-
Phosphorothioate analogues of nucleotides -tools for the investigation of biochemical processes
-
Eckstein F (1983) Phosphorothioate analogues of nucleotides -tools for the investigation of biochemical processes. Ang Chem 22: 423-506
-
(1983)
Ang Chem
, vol.22
, pp. 423-506
-
-
Eckstein, F.1
-
21
-
-
0027050144
-
Cloning of a delta opioid receptor by functional expression
-
Evans C J, Keith D E Jr, Morrison H, Magendzo K, Edwards R H (1992) Cloning of a delta opioid receptor by functional expression. Science 258: 1952-1955
-
(1992)
Science
, vol.258
, pp. 1952-1955
-
-
Evans, C.J.1
Keith Jr., D.E.2
Morrison, H.3
Magendzo, K.4
Edwards, R.H.5
-
22
-
-
0027275029
-
Primary structures and expression from cDNAs of rat opioid receptors from δ and μ -subtypes
-
Fukuda K, Katto S, Mori K, Nishi M, Takeshima H (1993) Primary structures and expression from cDNAs of rat opioid receptors from δ and μ -subtypes. FEBS Letts 327: 311-314
-
(1993)
FEBS Letts
, vol.327
, pp. 311-314
-
-
Fukuda, K.1
Katto, S.2
Mori, K.3
Nishi, M.4
Takeshima, H.5
-
23
-
-
0025155482
-
Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum
-
Graybiel A M, Moratalla R, Robertson H A (1990) Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matrix compartments and limbic subdivisions of the striatum. Proc Nat Acad Sci USA 87: 6912-6916
-
(1990)
Proc Nat Acad Sci USA
, vol.87
, pp. 6912-6916
-
-
Graybiel, A.M.1
Moratalla, R.2
Robertson, H.A.3
-
24
-
-
0026323898
-
Synthesis, biophysical and biological evaluation of 2′-modified antisense oligonucleotides
-
Guinosso C J, Hoke G J, Ecker D J, Mirabelli C K, Crooke S T, Cook P D (1991) Synthesis, biophysical and biological evaluation of 2′-modified antisense oligonucleotides. Nucleosides Nucleotides 10: 259-265
-
(1991)
Nucleosides Nucleotides
, vol.10
, pp. 259-265
-
-
Guinosso, C.J.1
Hoke, G.J.2
Ecker, D.J.3
Mirabelli, C.K.4
Crooke, S.T.5
Cook, P.D.6
-
25
-
-
0027310376
-
C-fos antisense in the nucleus accumbens blocks the locomotor stimulant action of cocaine
-
Heilig M, Engel J A, Söderpalm B (1993) C-fos antisense in the nucleus accumbens blocks the locomotor stimulant action of cocaine. Eur J Pharmac 236: 339-340
-
(1993)
Eur J Pharmac
, vol.236
, pp. 339-340
-
-
Heilig, M.1
Engel, J.A.2
Söderpalm, B.3
-
26
-
-
0000981276
-
Antisense technology. Prospects for treatment of neuropsychiatrie disorders
-
Heilig M (1994) Antisense technology. Prospects for treatment of neuropsychiatrie disorders. CNS Drugs 1: 405-409
-
(1994)
CNS Drugs
, vol.1
, pp. 405-409
-
-
Heilig, M.1
-
27
-
-
0028062148
-
Control of oncogene expression by antisense nucleic acids
-
Helene C (1994) Control of oncogene expression by antisense nucleic acids. Eur J Cancer 11: 1721-1726
-
(1994)
Eur J Cancer
, vol.11
, pp. 1721-1726
-
-
Helene, C.1
-
28
-
-
0026621815
-
The role of corticotropin-releasing hormone in the pathogenesis of Cushing's disease, anorexia nervosa, alcoholism, affective disorder and dementia
-
Holsboer F, Spengler D, Heuser I (1992) The role of corticotropin-releasing hormone in the pathogenesis of Cushing's disease, anorexia nervosa, alcoholism, affective disorder and dementia. Prog Brain Res 93: 385-417
-
(1992)
Prog Brain Res
, vol.93
, pp. 385-417
-
-
Holsboer, F.1
Spengler, D.2
Heuser, I.3
-
29
-
-
0028150874
-
Infusion into the brain of an antisense oligonucleotide to the immediate-early gene c-fos suppresses production of fos and produces a behavioural effect
-
Hooper M L, Chaisson B J, Robertson H A (1994) Infusion into the brain of an antisense oligonucleotide to the immediate-early gene c-fos suppresses production of fos and produces a behavioural effect. Neuroscience 63: 917-924
-
(1994)
Neuroscience
, vol.63
, pp. 917-924
-
-
Hooper, M.L.1
Chaisson, B.J.2
Robertson, H.A.3
-
30
-
-
0028183017
-
VII International Union of Pharmacology classification of receptor for 5-hydroxytryptamine (serotonin)
-
Hoyer D, Clarke D E, Fozard J R, Hartig P R, Martin G R, Mylecharane E J, Saxena P R, Humphrey P P A (1994) VII International Union of Pharmacology classification of receptor for 5-hydroxytryptamine (serotonin). Pharmac Rev 46: 157-203
-
(1994)
Pharmac Rev
, vol.46
, pp. 157-203
-
-
Hoyer, D.1
Clarke, D.E.2
Fozard, J.R.3
Hartig, P.R.4
Martin, G.R.5
Mylecharane, E.J.6
Saxena, P.R.7
Humphrey, P.P.A.8
-
31
-
-
0026486816
-
Pleiotropic effects of a null mutation in the c-fos proto-oncogene
-
Johnson R S, Spiegelman B M, Papaioannou V (1992) Pleiotropic effects of a null mutation in the c-fos proto-oncogene. Cell 71: 577-586
-
(1992)
Cell
, vol.71
, pp. 577-586
-
-
Johnson, R.S.1
Spiegelman, B.M.2
Papaioannou, V.3
-
32
-
-
0026877363
-
Liposomes as a drug delivery system for antisense oligonucleotides
-
Juliano R L, Akhtar S (1992) Liposomes as a drug delivery system for antisense oligonucleotides. Antisense Res Dev 2:165-176
-
(1992)
Antisense Res Dev
, vol.2
, pp. 165-176
-
-
Juliano, R.L.1
Akhtar, S.2
-
33
-
-
0029417083
-
A gamma 2 subunit induces loss of neurones in rat hippocampus
-
A gamma 2 subunit induces loss of neurones in rat hippocampus. Neurosci Letts 202:97-100
-
(1995)
Neurosci Letts
, vol.202
, pp. 97-100
-
-
Karle, J.1
Witt, M.R.2
Neilsen, M.3
-
34
-
-
0028829799
-
Inhibition of herpes simplex virus replication by antisense oligo-2′-O-methylribonucleoside methylphosphonates
-
Kean J M, Kipp S A, Miller P S, Kulka M, Aurelian L (1995) Inhibition of herpes simplex virus replication by antisense oligo-2′-O-methylribonucleoside methylphosphonates. Biochemistry 34: 14617-14620
-
(1995)
Biochemistry
, vol.34
, pp. 14617-14620
-
-
Kean, J.M.1
Kipp, S.A.2
Miller, P.S.3
Kulka, M.4
Aurelian, L.5
-
35
-
-
0027052952
-
The δ-opioid receptor: Isolation of a cDNA by expression cloning and pharmacological characterisation
-
Kieffer B L, Befort K, Gaveriaux-Ruff C, Hirth C G (1992) The δ-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterisation. Proc Nat Acad Sci USA 89: 12048-12052
-
(1992)
Proc Nat Acad Sci USA
, vol.89
, pp. 12048-12052
-
-
Kieffer, B.L.1
Befort, K.2
Gaveriaux-Ruff, C.3
Hirth, C.G.4
-
36
-
-
0027203638
-
BCR-ABL antisense purging in chronic myeloid leukaemia (3)
-
Kirkland M A, O'Brian S G, McDonald C, Davidson R J, Cross N C R, Goldman J M (1993) BCR-ABL antisense purging in chronic myeloid leukaemia (3). Lancet 342: 614
-
(1993)
Lancet
, vol.342
, pp. 614
-
-
Kirkland, M.A.1
O'Brian, S.G.2
McDonald, C.3
Davidson, R.J.4
Cross, N.C.R.5
Goldman, J.M.6
-
37
-
-
0027058137
-
Ablation of transplanted HTLV-I tax-transformed tumors in mice by antisense inhibition of NF-Kappa B
-
Kitajama I, Shinohara T, Bilakovics J, Brown D A, Xu X, Nerenberg M (1993) Ablation of transplanted HTLV-I tax-transformed tumors in mice by antisense inhibition of NF-Kappa B. Science 258: 1792-1795
-
(1993)
Science
, vol.258
, pp. 1792-1795
-
-
Kitajama, I.1
Shinohara, T.2
Bilakovics, J.3
Brown, D.A.4
Xu, X.5
Nerenberg, M.6
-
38
-
-
0001314180
-
Dopamine addiction and reward
-
Koob G F (1992) Dopamine addiction and reward. Semin Neurosci 4: 139-148
-
(1992)
Semin Neurosci
, vol.4
, pp. 139-148
-
-
Koob, G.F.1
-
39
-
-
0028840837
-
Antisense oligonucleotides are effective inhibitors of hepatitis B replication in vitro
-
Korba B E, Gerin J L (1995) Antisense oligonucleotides are effective inhibitors of hepatitis B replication in vitro. Antiviral Res 28: 225-242
-
(1995)
Antiviral Res
, vol.28
, pp. 225-242
-
-
Korba, B.E.1
Gerin, J.L.2
-
40
-
-
0028919360
-
Measles virus antisense sequences specifically cure cells persistently infected with measles virus
-
Koschel K, Brinckmann U, Hoyningen-Huene V V (1995) Measles virus antisense sequences specifically cure cells persistently infected with measles virus. Virology 207: 168-178
-
(1995)
Virology
, vol.207
, pp. 168-178
-
-
Koschel, K.1
Brinckmann, U.2
Hoyningen-Huene, V.V.3
-
41
-
-
0027512851
-
Uptake and efficacy of phosphodiester and modified antisense oligonucleotides in primary cell cultures
-
Krieg A M (1993) Uptake and efficacy of phosphodiester and modified antisense oligonucleotides in primary cell cultures. Clin Chem 39: 710-712
-
(1993)
Clin Chem
, vol.39
, pp. 710-712
-
-
Krieg, A.M.1
-
42
-
-
0027473513
-
Modification of a phosphodiester oligodeoxyribonucleotide by a 5′-cholesteryl moiety increases cellular association and improves efficacy
-
Krieg A M, Tonkinson J, Matson S, Zhao Q, Saxon M, Zhang L-M, Bhanja U, Yakubov L, Stein C A (1993) Modification of a phosphodiester oligodeoxyribonucleotide by a 5′-cholesteryl moiety increases cellular association and improves efficacy. Proc Nat Acad Sci USA 90:1048-1052
-
(1993)
Proc Nat Acad Sci USA
, vol.90
, pp. 1048-1052
-
-
Krieg, A.M.1
Tonkinson, J.2
Matson, S.3
Zhao, Q.4
Saxon, M.5
Zhang, L.-M.6
Bhanja, U.7
Yakubov, L.8
Stein, C.A.9
-
43
-
-
0028951984
-
Treatment with antisense oligodeoxynucleotide to a conserved sequence of opioid receptors inhibits antinociceptive effects of delta subtype selective ligands
-
Lai J, Bilsky E J, Porreca F (1995) Treatment with antisense oligodeoxynucleotide to a conserved sequence of opioid receptors inhibits antinociceptive effects of delta subtype selective ligands. J Recept Sig Transd Res 15: 643-650
-
(1995)
J Recept Sig Transd Res
, vol.15
, pp. 643-650
-
-
Lai, J.1
Bilsky, E.J.2
Porreca, F.3
-
44
-
-
0028981589
-
1 vasopressin receptor antisense oligodeoxynucleotide into septum reduces vasopressin binding, social discrimination abilities, and anxiety-related behaviour in rats
-
1 vasopressin receptor antisense oligodeoxynucleotide into septum reduces vasopressin binding, social discrimination abilities, and anxiety-related behaviour in rats. J Neurosci 15: 4250-4258
-
(1995)
J Neurosci
, vol.15
, pp. 4250-4258
-
-
Landgraf, R.1
Gerstberger, R.2
Montkowski, A.3
Probst, J.C.4
Wotjak, C.T.5
Holsboer, F.6
Engelmann, M.7
-
45
-
-
0026847155
-
Brain mechanisms of emotion and emotional learning
-
LeDoux J E (1992) Brain mechanisms of emotion and emotional learning. Curr Opin Neurobiol 2: 191-197
-
(1992)
Curr Opin Neurobiol
, vol.2
, pp. 191-197
-
-
LeDoux, J.E.1
-
46
-
-
0002447036
-
Antisense technology in behavioural neuroscience
-
McCarthy M M, Brooks B J, Pfaus J, Brown H E, Flanagan L M, Schwartz-Giblin S, Pfaff D N (1993) Antisense technology in behavioural neuroscience. Neuroprotocols 2:67-74
-
(1993)
Neuroprotocols
, vol.2
, pp. 67-74
-
-
McCarthy, M.M.1
Brooks, B.J.2
Pfaus, J.3
Brown, H.E.4
Flanagan, L.M.5
Schwartz-Giblin, S.6
Pfaff, D.N.7
-
47
-
-
0028136392
-
Inhibition of rat sexual behaviour by antisense oligonucleotides in the progesterone receptor
-
Mani S K, Blaustein J D, Allen J M C, Law S W, O'Malley B W, Clark J H (1994a) Inhibition of rat sexual behaviour by antisense oligonucleotides in the progesterone receptor. Endocrinology 135: 1409-1414
-
(1994)
Endocrinology
, vol.135
, pp. 1409-1414
-
-
Mani, S.K.1
Blaustein, J.D.2
Allen, J.M.C.3
Law, S.W.4
O'Malley, B.W.5
Clark, J.H.6
-
48
-
-
0028037785
-
Convergent pathways for steroid hormone and neurotransmitter-induced rat sexual behaviour
-
Mani S K, Allen J M C, Clark J H, Blaustein J D, O'Malley B W (1994b) Convergent pathways for steroid hormone and neurotransmitter-induced rat sexual behaviour. Science 265: 1246-1249
-
(1994)
Science
, vol.265
, pp. 1246-1249
-
-
Mani, S.K.1
Allen, J.M.C.2
Clark, J.H.3
Blaustein, J.D.4
O'Malley, B.W.5
-
49
-
-
0029150233
-
Antisense vasopressin oligonucleotides: Uptake, turnover, distribution, toxicity and behavioural effects
-
Meeker R, LeGrand G, Ramirez J, Smith T, Shih Y-H (1995) Antisense vasopressin oligonucleotides: Uptake, turnover, distribution, toxicity and behavioural effects. J Neuroendocrinol 7: 419-428
-
(1995)
J Neuroendocrinol
, vol.7
, pp. 419-428
-
-
Meeker, R.1
LeGrand, G.2
Ramirez, J.3
Smith, T.4
Shih, Y.-H.5
-
50
-
-
0026644603
-
Excitatory amino acids in epilepsy and potential novel therapies
-
Meldrum B S (1992) Excitatory amino acids in epilepsy and potential novel therapies. Epilepsy Res 12: 189-196
-
(1992)
Epilepsy Res
, vol.12
, pp. 189-196
-
-
Meldrum, B.S.1
-
51
-
-
0025063609
-
Excitatory amino acid neurotoxicity and neurodegenerative disease
-
Meldrum B, Garthwaite J (1990) Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmac Sci 11: 379-387
-
(1990)
Trends Pharmac Sci
, vol.11
, pp. 379-387
-
-
Meldrum, B.1
Garthwaite, J.2
-
52
-
-
0027381434
-
Cloning and pharmacological characterisation of a rat kappa-opioid receptor
-
Meng F, Xie G-X, Thompson R C, Mansour A, Goldstein A, Watson S J, Akil H (1993) Cloning and pharmacological characterisation of a rat kappa-opioid receptor. Proc Nat Acad Sci USA 90: 9954-9958
-
(1993)
Proc Nat Acad Sci USA
, vol.90
, pp. 9954-9958
-
-
Meng, F.1
Xie, G.-X.2
Thompson, R.C.3
Mansour, A.4
Goldstein, A.5
Watson, S.J.6
Akil, H.7
-
53
-
-
0019891872
-
Biochemical and biological effects of non-ionic nucleic acid methylphosphonates
-
Miller P S, McFarland K B, Jayaraman K, Ts'o POP (1981) Biochemical and biological effects of non-ionic nucleic acid methylphosphonates. Biochemistry 20: 1874-1880
-
(1981)
Biochemistry
, vol.20
, pp. 1874-1880
-
-
Miller, P.S.1
McFarland, K.B.2
Jayaraman, K.3
Ts'o, P.O.P.4
-
54
-
-
0028644159
-
C-fos expression in the amygdala: In vivo antisense modulation and role in anxiety
-
Möller C, Bing O, Heilig M (1994) C-fos expression in the amygdala: in vivo antisense modulation and role in anxiety. Cell Mol Neurobiol 14: 415-423
-
(1994)
Cell Mol Neurobiol
, vol.14
, pp. 415-423
-
-
Möller, C.1
Bing, O.2
Heilig, M.3
-
55
-
-
0028981854
-
Stimulation of spinal δ-opioid receptors in mice selectively enhances the attenuation of δ-opioid receptor-mediated antinociception by antisense oligodeoxynucleotide
-
Narita M, Tseng L F (1995) Stimulation of spinal δ-opioid receptors in mice selectively enhances the attenuation of δ-opioid receptor-mediated antinociception by antisense oligodeoxynucleotide. Eur J Pharmac 284: 185-189
-
(1995)
Eur J Pharmac
, vol.284
, pp. 185-189
-
-
Narita, M.1
Tseng, L.F.2
-
57
-
-
0028989836
-
2-adrenoceptors and blood pressure regulation in the rat
-
2-adrenoceptors and blood pressure regulation in the rat. Eur J Pharmac 278: 183-185
-
(1995)
Eur J Pharmac
, vol.278
, pp. 183-185
-
-
Nunes, J.P.1
-
58
-
-
0028810121
-
Cellular uptake of intracerebrally administered oligodeoxynucleotides in mouse brain
-
Ogawa S, Brown H E, Okano H J, Pfaff D N (1995) Cellular uptake of intracerebrally administered oligodeoxynucleotides in mouse brain. Reg Pep 59:143-149
-
(1995)
Reg Pep
, vol.59
, pp. 143-149
-
-
Ogawa, S.1
Brown, H.E.2
Okano, H.J.3
Pfaff, D.N.4
-
59
-
-
0024446199
-
Acute effects of alprazolam and adinazolam on the concentrations of corticotropin-releasing factor in the rat brain
-
Owens M J, Bissette G, Nemeroff C B (1989) Acute effects of alprazolam and adinazolam on the concentrations of corticotropin-releasing factor in the rat brain. Synapse 4: 196-202
-
(1989)
Synapse
, vol.4
, pp. 196-202
-
-
Owens, M.J.1
Bissette, G.2
Nemeroff, C.B.3
-
60
-
-
0026332080
-
The physiology and pharmacology of corticotropin-releasing factor
-
Owens M J, Nemeroff C B (1991) The physiology and pharmacology of corticotropin-releasing factor. Pharmac Rev 43: 425-473
-
(1991)
Pharmac Rev
, vol.43
, pp. 425-473
-
-
Owens, M.J.1
Nemeroff, C.B.2
-
61
-
-
0029065852
-
3-related opioid receptor
-
3-related opioid receptor. Mol Pharmac 47: 1180-1188
-
(1995)
Mol Pharmac
, vol.47
, pp. 1180-1188
-
-
Pan, Y.-X.1
Cheng, J.2
Xu, J.3
Rossi, G.4
Jacobson, E.5
Ryan-Moro, J.6
Brooks, A.I.7
Dean, G.E.8
Standifer, K.M.9
Pasternak, G.W.10
-
62
-
-
0029097278
-
Mapping of opioid receptors using antisense oligodeoxynucleotides: Correlating their molecular biology and pharmacology
-
Pasternak G W, Standifer K M (1995) Mapping of opioid receptors using antisense oligodeoxynucleotides: correlating their molecular biology and pharmacology.Trends Pharmac Sci 16: 344-350
-
(1995)
Trends Pharmac Sci
, vol.16
, pp. 344-350
-
-
Pasternak, G.W.1
Standifer, K.M.2
-
63
-
-
0027209290
-
Antagonism of cocaine self-administration by preferential dopamine autoreceptor antagonist, (+)-AJ 76
-
Richardson N R, Piercy M F, Svensson K, Collins R J, Myers J E, Roberts D C (1993) Antagonism of cocaine self-administration by preferential dopamine autoreceptor antagonist, (+)-AJ 76. Brain Res 619: 15-23
-
(1993)
Brain Res
, vol.619
, pp. 15-23
-
-
Richardson, N.R.1
Piercy, M.F.2
Svensson, K.3
Collins, R.J.4
Myers, J.E.5
Roberts, D.C.6
-
64
-
-
0028261434
-
Binding of typical and atypical antipsychotic agents of 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors
-
Roth B L, Craigo S C, Choudhary M S, Uluer A, Monsma F J, Shen Y, Meltzer H Y, Sibley D R (1994) Binding of typical and atypical antipsychotic agents of 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmac Exp Ther 268: 1403-1410
-
(1994)
J Pharmac Exp Ther
, vol.268
, pp. 1403-1410
-
-
Roth, B.L.1
Craigo, S.C.2
Choudhary, M.S.3
Uluer, A.4
Monsma, F.J.5
Shen, Y.6
Meltzer, H.Y.7
Sibley, D.R.8
-
65
-
-
0027212940
-
6) receptor: Molecular cloning, localisation and stimulation of cAMP accumulation
-
6) receptor: molecular cloning, localisation and stimulation of cAMP accumulation. Biochem Biophys Res Commun 193: 269-276
-
(1993)
Biochem Biophys Res Commun
, vol.193
, pp. 269-276
-
-
Ruat, M.1
Traiffort, E.2
Arrang, J.M.3
Tardivel-Lacombe, J.4
Diaz, J.5
Leurs, R.6
Schwartz, J.C.7
-
66
-
-
0017068246
-
Antipsychotic drug doses and neuroleptic/dopamine receptors
-
Seeman P, Lee T, Chau-Wang M, Wang K (1976) Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature 261: 717-719
-
(1976)
Nature
, vol.261
, pp. 717-719
-
-
Seeman, P.1
Lee, T.2
Chau-Wang, M.3
Wang, K.4
-
67
-
-
0019054016
-
Brain DA receptors
-
Seeman P (1980) Brain DA receptors. Pharmac Rev 32: 229-313
-
(1980)
Pharmac Rev
, vol.32
, pp. 229-313
-
-
Seeman, P.1
-
68
-
-
0028167698
-
2 dopamine receptor antisense oligodeoxynucleotides establishes a role for nigrostriatal D2 autoreceptors in the motor actions of cocaine
-
2 dopamine receptor antisense oligodeoxynucleotides establishes a role for nigrostriatal D2 autoreceptors in the motor actions of cocaine. Mol Pharmac 46: 51-57
-
(1994)
Mol Pharmac
, vol.46
, pp. 51-57
-
-
Silvia, C.P.1
King, G.R.2
Lee, T.H.3
Xue, Z.-Y.4
Caron, M.G.5
Ellinwood, E.H.6
-
69
-
-
0026641052
-
Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo
-
Simons M, Edelman E R, DeKeyser J-L, Langer R, Rosenberg R D (1992) Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo. Nature 359: 67-70
-
(1992)
Nature
, vol.359
, pp. 67-70
-
-
Simons, M.1
Edelman, E.R.2
DeKeyser, J.-L.3
Langer, R.4
Rosenberg, R.D.5
-
70
-
-
0028625387
-
Corticotrophin-releasing hormone (CRH) antisense oligodeoxynucleotide treatment attenuates social defeat-induced anxiety in rats
-
Skutella T, Montkowski A, Stöhr T, Probst J C, Landgraf R, Holsboer F, Jirikowski G F (1994a) Corticotrophin-releasing hormone (CRH) antisense oligodeoxynucleotide treatment attenuates social defeat-induced anxiety in rats. Cell Mol Neurobiol 14: 579-588
-
(1994)
Cell Mol Neurobiol
, vol.14
, pp. 579-588
-
-
Skutella, T.1
Montkowski, A.2
Stöhr, T.3
Probst, J.C.4
Landgraf, R.5
Holsboer, F.6
Jirikowski, G.F.7
-
71
-
-
0028267577
-
Ventral tegmental area (VTA) injections of tyrosine hydroxylase phosphorothioate antisense oligonucleotide suppress operant behaviour in rats
-
Skutella T, Probst J C, Jirikowski G F, Holsboer F, Spangel R (1994b) Ventral tegmental area (VTA) injections of tyrosine hydroxylase phosphorothioate antisense oligonucleotide suppress operant behaviour in rats. Neurosci Letts 167: 55-58
-
(1994)
Neurosci Letts
, vol.167
, pp. 55-58
-
-
Skutella, T.1
Probst, J.C.2
Jirikowski, G.F.3
Holsboer, F.4
Spangel, R.5
-
73
-
-
0010454141
-
G protein-coupled serotonin receptors - Multiple subtypes, multiple opportunities
-
Smith D W, Parker E M (1995) G protein-coupled serotonin receptors - multiple subtypes, multiple opportunities. Curr Pharmaceut Des: 1:363-372
-
(1995)
Curr Pharmaceut des
, vol.1
, pp. 363-372
-
-
Smith, D.W.1
Parker, E.M.2
-
75
-
-
0027724885
-
Antisense oligonucleotide to c-fos induces ipsilateral rotational behaviour to d-amphetamine
-
Sommer W, Bjelke B, Ganten D, Fuxe K (1993) Antisense oligonucleotide to c-fos induces ipsilateral rotational behaviour to d-amphetamine. Neuroreport 5: 277-280
-
(1993)
Neuroreport
, vol.5
, pp. 277-280
-
-
Sommer, W.1
Bjelke, B.2
Ganten, D.3
Fuxe, K.4
-
76
-
-
0028327150
-
Selective loss of δ opioid analgesia and binding by a δ opioid receptor
-
Standifer K M, Chien C-C, Wahlestedt C, Brown G P, Pasternak G W (1994) Selective loss of δ opioid analgesia and binding by a δ opioid receptor. Neuron 12: 805-810
-
(1994)
Neuron
, vol.12
, pp. 805-810
-
-
Standifer, K.M.1
Chien, C.-C.2
Wahlestedt, C.3
Brown, G.P.4
Pasternak, G.W.5
-
77
-
-
0026737456
-
Antisense oligonucleotides - Promises and pitfalls
-
Stein C A (1992) Antisense oligonucleotides - promises and pitfalls. Leukemia 6: 967-974
-
(1992)
Leukemia
, vol.6
, pp. 967-974
-
-
Stein, C.A.1
-
78
-
-
0027376439
-
Antisense oligonucleotides as therapeutic agents - Is the bullet really magical?
-
Stein C A, Cheng Y-C (1993) Antisense oligonucleotides as therapeutic agents - Is the bullet really magical? Science 261: 1004-1012
-
(1993)
Science
, vol.261
, pp. 1004-1012
-
-
Stein, C.A.1
Cheng, Y.-C.2
-
79
-
-
0041582974
-
Inhibition of rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
-
Stephenson M L, Zamecnik P C (1978) Inhibition of rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc Nat Acad Sci USA 75: 285-288
-
(1978)
Proc Nat Acad Sci USA
, vol.75
, pp. 285-288
-
-
Stephenson, M.L.1
Zamecnik, P.C.2
-
80
-
-
0026511674
-
Stimulation of cell division and fibroblast focus formation by antisense repression of retinaoblastoma protein synthesis
-
Strauss M, Hering S, Lieber A, Herrmann G, Griffin B E, Arnold W (1992) Stimulation of cell division and fibroblast focus formation by antisense repression of retinaoblastoma protein synthesis. Oncogene 7: 769-773
-
(1992)
Oncogene
, vol.7
, pp. 769-773
-
-
Strauss, M.1
Hering, S.2
Lieber, A.3
Herrmann, G.4
Griffin, B.E.5
Arnold, W.6
-
81
-
-
0029155480
-
Pretreatment with antisense oligodeoxy-nucleotides directed against the NMDA-R1 receptor enhances survival and behavioural recovery following traumatic brain injury in rats
-
Sun F-S, Faden A I (1995) Pretreatment with antisense oligodeoxy-nucleotides directed against the NMDA-R1 receptor enhances survival and behavioural recovery following traumatic brain injury in rats. Brain Res 693: 163-168
-
(1995)
Brain Res
, vol.693
, pp. 163-168
-
-
Sun, F.-S.1
Faden, A.I.2
-
82
-
-
0025992317
-
The effect of a competitive NMDA receptor antagonist (CGS-19755) on cerebral blood flow and pH in focal ischaemia
-
Takizawa S, Hogan M, Hakim AM (1991) The effect of a competitive NMDA receptor antagonist (CGS-19755) on cerebral blood flow and pH in focal ischaemia. J Cereb Blood Flow Metab 11: 786-793
-
(1991)
J Cereb Blood Flow Metab
, vol.11
, pp. 786-793
-
-
Takizawa, S.1
Hogan, M.2
Hakim, A.M.3
-
83
-
-
0001818226
-
Forebrain mechanisms in the relief of fear: The role of the lateral septum
-
Thomas E (1988) Forebrain mechanisms in the relief of fear: The role of the lateral septum. Psychobiology 16: 36-44
-
(1988)
Psychobiology
, vol.16
, pp. 36-44
-
-
Thomas, E.1
-
84
-
-
0002656848
-
Artificial regulation of gene expression by complementary oligonucleotides - An overview
-
Wiley-Liss, New York
-
Toulme JJ (1992) Artificial regulation of gene expression by complementary oligonucleotides - an overview. In Antisense RNA and DNA. Wiley-Liss, New York, pp. 175-194
-
(1992)
Antisense RNA and DNA
, pp. 175-194
-
-
Toulme, J.J.1
-
85
-
-
0015004136
-
A simple and reliable conflict procedure for testing anti-anxiety agents
-
Vogel J R, Beer R, Clodt D E (1971) A simple and reliable conflict procedure for testing anti-anxiety agents. Psychopharmacologia 21: 1-7
-
(1971)
Psychopharmacologia
, vol.21
, pp. 1-7
-
-
Vogel, J.R.1
Beer, R.2
Clodt, D.E.3
-
87
-
-
0027246678
-
Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimadines
-
Wagner R W, Matteucci M D, Lewis J G, Gutierrez A Z, Moulds S C, Fruehler B C (1993) Antisense gene inhibition by oligonucleotides containing C-5 propyne pyrimadines. Science 260: 1510-1513
-
(1993)
Science
, vol.260
, pp. 1510-1513
-
-
Wagner, R.W.1
Matteucci, M.D.2
Lewis, J.G.3
Gutierrez, A.Z.4
Moulds, S.C.5
Fruehler, B.C.6
-
88
-
-
0028019410
-
Gene inhibition using antisense oligodeoxynucleotides
-
Wagner R W (1994) Gene inhibition using antisense oligodeoxynucleotides. Nature 372: 333-335
-
(1994)
Nature
, vol.372
, pp. 333-335
-
-
Wagner, R.W.1
-
89
-
-
0027207494
-
Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurones from excitotoxicity and reduce focal ischaemic infarctions
-
Wahlestedt C, Golanov E, Yamamoto S, Yee F, Ericson H, Yoo H, Inturrisi C E, Reis D J (1993a) Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurones from excitotoxicity and reduce focal ischaemic infarctions. Nature 363: 260-263
-
(1993)
Nature
, vol.363
, pp. 260-263
-
-
Wahlestedt, C.1
Golanov, E.2
Yamamoto, S.3
Yee, F.4
Ericson, H.5
Yoo, H.6
Inturrisi, C.E.7
Reis, D.J.8
-
90
-
-
0027450169
-
Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides
-
Wahlestedt C, Merlo-Pich E, Koob G F, Yee F, Heilig M (1993b) Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides. Science 259: 528-531
-
(1993)
Science
, vol.259
, pp. 528-531
-
-
Wahlestedt, C.1
Merlo-Pich, E.2
Koob, G.F.3
Yee, F.4
Heilig, M.5
-
91
-
-
0028180462
-
Antisense oligonucleotide strategies in neuropharmacology
-
Wahlestedt C (1994) Antisense oligonucleotide strategies in neuropharmacology. Trends Pharmac Sci 15: 42-46
-
(1994)
Trends Pharmac Sci
, vol.15
, pp. 42-46
-
-
Wahlestedt, C.1
-
92
-
-
0024041180
-
Role of RNaseH in hybrid-arrested translation by antisense oligonucleotides
-
Walder R Y, Walder J A (1988) Role of RNaseH in hybrid-arrested translation by antisense oligonucleotides. Proc Nat Acad Sci 85: 5011-5015
-
(1988)
Proc Nat Acad Sci
, vol.85
, pp. 5011-5015
-
-
Walder, R.Y.1
Walder, J.A.2
-
93
-
-
0027070472
-
Bone and haematopoietic defects in mice lacking c-fos
-
Wang Z Q, Ovitt C, Grigoriadis A E, Mohle-Steinlein U, Ruther U, Wagner E F (1992) Bone and haematopoietic defects in mice lacking c-fos. Nature 360: 741-745
-
(1992)
Nature
, vol.360
, pp. 741-745
-
-
Wang, Z.Q.1
Ovitt, C.2
Grigoriadis, A.E.3
Mohle-Steinlein, U.4
Ruther, U.5
Wagner, E.F.6
-
95
-
-
0027298897
-
Stability, clearance and deposition of intraventricularly administered oligodeoxynucleotides: Implications for therapeutic application within the central nervous system
-
Whitesell L, Geselowitz D, Chavany C, Fahmy B, Walbridge S, Alger J R, Neckers L M (1993) Stability, clearance and deposition of intraventricularly administered oligodeoxynucleotides: implications for therapeutic application within the central nervous system. Proc Nat Acad Sci USA 90: 4665-4669
-
(1993)
Proc Nat Acad Sci USA
, vol.90
, pp. 4665-4669
-
-
Whitesell, L.1
Geselowitz, D.2
Chavany, C.3
Fahmy, B.4
Walbridge, S.5
Alger, J.R.6
Neckers, L.M.7
-
96
-
-
0022780091
-
Oligonucleotide stability in subcellular extracts and culture media
-
Wickstrom E (1986) Oligonucleotide stability in subcellular extracts and culture media. J Biochem Biophys Meth 13: 97-102
-
(1986)
J Biochem Biophys Meth
, vol.13
, pp. 97-102
-
-
Wickstrom, E.1
-
98
-
-
0027490804
-
2 receptors: Behaviour correlates
-
2 receptors: behaviour correlates. Neurosci Letts 161: 223-226
-
(1993)
Neurosci Letts
, vol.161
, pp. 223-226
-
-
Zhang, M.1
Creese, I.2
-
99
-
-
0028170936
-
1 dopamine receptor-mediated behaviours in normal mice and in mice lesioned with 6-hydroxydopamine
-
1 dopamine receptor-mediated behaviours in normal mice and in mice lesioned with 6-hydroxydopamine. J Pharmac Exp Ther 271: 1462-1470
-
(1994)
J Pharmac Exp Ther
, vol.271
, pp. 1462-1470
-
-
Zhang, S.1
Zhou, L.2
Weiss, B.3
-
100
-
-
0042082583
-
2 receptor subtypes in locomotor activity and stereotypy: Antisense knockout studies
-
2 receptor subtypes in locomotor activity and stereotypy: Antisense knockout studies. Soc Neurosci Abstr 21: 364
-
(1995)
Soc Neurosci Abstr
, vol.21
, pp. 364
-
-
Zhang, M.1
Quagazzal, A.2
Creese, I.3
|