Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 3, 1997, Pages 923-927

  Signorini, Stefano ^a   Liao, Y Joyce ^b   Duncan, Stephen A ^a   Jan, Lily Y ^b   Stoffel, Markus ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b UNIVERSITY OF SAN FRANCISCO   (United States)

Author keywords

cerebellum; embryonic stem cells; genetics; GIRK1; weaver

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; GUANINE NUCLEOTIDE BINDING PROTEIN; POTASSIUM CHANNEL; POTASSIUM ION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CEREBELLUM; CHANNEL GATING; CONTROLLED STUDY; EMBRYO; GENE DOSAGE; MALE; MOUSE; NERVE CELL EXCITABILITY; NONHUMAN; PHENOTYPE; POINT MUTATION; POTASSIUM CURRENT; PRIORITY JOURNAL; SEIZURE SUSCEPTIBILITY;

ANIMALS; BRAIN CHEMISTRY; CEREBELLUM; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GABA ANTAGONISTS; GENE DOSAGE; GENOTYPE; GTP-BINDING PROTEINS; MALE; MICE; MICE, KNOCKOUT; MICE, NEUROLOGIC MUTANTS; PENTYLENETETRAZOLE; PHENOTYPE; POINT MUTATION; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RNA, MESSENGER; SEIZURES;

EID: 0031016163     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.3.923     Document Type: Article

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