Autophosphorylation at Thr286 of the α calcium-calmodulin kinase II in LTP and learning

Science

Volumn 279, Issue 5352, 1998, Pages 870-873

  Giese, Karl Peter ^a   Fedorov, Nikolai B ^a   Filipkowski, Robert K ^b   Silva, Alcino J ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN KINASE (CALCIUM,CALMODULIN) II; SYNAPTOPHYSIN; THREONINE; 2 AMINO 5 PHOSPHONOVALERIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; CALMODULIN; CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN-DEPENDENT PROTEIN KINASE II; PHOSPHOTHREONINE; PICROTOXIN; PROTEIN KINASE (CALCIUM,CALMODULIN);

ANIMAL EXPERIMENT; ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; LEARNING; LONG TERM POTENTIATION; MAZE TEST; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; SPATIAL ORIENTATION; ANIMAL; C57BL MOUSE; DRUG EFFECT; GENE TARGETING; GENETICS; METABOLISM; MOUSE MUTANT; PATCH CLAMP; PHOSPHORYLATION; PHYSIOLOGY; PYRAMIDAL NERVE CELL; SYNAPTIC TRANSMISSION;

2-AMINO-5-PHOSPHONOVALERATE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALMODULIN; GENE TARGETING; HIPPOCAMPUS; LONG-TERM POTENTIATION; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; PHOSPHOTHREONINE; PICROTOXIN; POINT MUTATION; PYRAMIDAL CELLS; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTIC TRANSMISSION;

EID: 0032488659     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.279.5352.870     Document Type: Article

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52. We thank P. Chen, K. Fox, P. W. Frankland, J. H. Kogan, J. E. Lisman, R. Malinow, K. Mizuno, A. Nagy, M. N. Waxham, and D.-J. Zuo for helpful discussions and materials. K.P.G. was supported by a European Molecular Biology Organization and Deutsche Forschungsgemeinschaft fellowship. R.K.F. was supported by the Foundation for Experimental and Clinical Oncology, Poland. A.J.S. was supported by grants from the Whitehall, Beckman, Klingenstein, and McKnight Foundations and NIH (AG13622).