Opioid-related changes in nociceptive threshold and in tissue levels of enkephalins after target disruption of the gene for neutral endopeptidase (EC 3.4.24.11) in mice

Neuroscience Letters

Volumn 234, Issue 1, 1997, Pages 27-30

  Saria, A ^a,b   Hauser, K F ^b   Traurig, H H ^b   Turbek, C S ^b   Hersh, L ^c   Gerard, C ^d  

^a Clinic of Psychiatry   (Austria)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Enkephalin levels; Enkephalinase; Hot plate test; Knockout mice; Neutral endopeptidase; Thermonociceptive threshold

Indexed keywords

ENKEPHALIN; PROTEINASE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME LOCALIZATION; HEAT SENSITIVITY; MOUSE; NOCICEPTION; NONHUMAN; PAIN; PAIN THRESHOLD; PRIORITY JOURNAL; TISSUE LEVEL;

ANALGESICS, OPIOID; ANIMALS; ENKEPHALIN, LEUCINE; ENKEPHALIN, METHIONINE; MICE; MICE, KNOCKOUT; MORPHINE; NEPRILYSIN; PAIN THRESHOLD; PHENOTYPE; TEMPERATURE;

EID: 0030756672     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(97)00660-5     Document Type: Article

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