Impaired locomotion and dopamine signaling in retinoid receptor mutant mice

Science

Volumn 279, Issue 5352, 1998, Pages 863-867

  Krȩzel, Wojciech ^a   Ghyselinck, Norbert ^a   Samad, Tarek A ^a   Dupé, Valérie ^a   Kastner, Philippe ^a   Borrelli, Emiliana ^a   Chambon, Pierre ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; ENKEPHALIN; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; LOCOMOTION; MESOLIMBIC DOPAMINERGIC SYSTEM; MOUSE; NONHUMAN; NORTHERN BLOTTING; PARKINSON DISEASE; PRIORITY JOURNAL; SCHIZOPHRENIA;

ANIMALS; COCAINE; CORPUS STRIATUM; DIMERIZATION; DOPAMINE; LOCOMOTION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; MUSCLE, SKELETAL; PARKINSON DISEASE; PERIPHERAL NERVOUS SYSTEM; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0032488783     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.279.5352.863     Document Type: Article

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35. We thank M. Le Meur for her collaboration; P. Oberling for help in statistical calculations; B. Féret, B. Bondeau, and the staff of the animal facilities for technical assistance; and J. M. LaFontaine and C. Werlé for help in preparation of the manuscript. Supported by funds from CNRS, INSERM, the Collège de France, the Centre Hospitalier Universitaire Régional, the Association pour la Recherche sur la Cancer (ARC), the Human Frontier Science Program, and Bristol-Myers Squibb. W.K. was a recipient of a fellowship from the Ministère de la Recherche and ARC and T.A-S. was a recipient of a Bourse de Docteur Ingénieur from CNRS.